BIOJECT INC. Patent applications |
Patent application number | Title | Published |
20140171918 | USE OF A NOVEL SUBCUTANEOUS NEEDLE-FREE TECHNIQUE TO DELIVER TESTOSTERONE IN HYPOGONADAL MEN - Embodiments herein are directed to methods for increasing testosterone levels in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of testosterone by needle-free injection to an injection site. Some embodiments are further directed to a method of increasing testosterone levels in a subject in need thereof, by administering to the subject a pharmaceutical composition comprising a therapeutically effective amount of testosterone and a pharmaceutically acceptable carrier by needle-free injection. Some embodiments are directed to a method of minimizing fluctuations in testosterone levels in a subject diagnosed with hypogonadism, comprising serially administering to the subject a therapeutically effective amount of testosterone by needle-free injection to an injection site. | 06-19-2014 |
20130304017 | PEFORMANCE OF NEEDLE-FREE INJECTION ACCORDING TO KNOWN RELATIONSHIPS - In various embodiments, an injector control system may be configured to control a needle-free injector to inject fluid injectate to a desired penetration depth. The injection control system may also be configured to receive injection performance data and use the injection performance data to make further adjustments to the needle-free injector. In various embodiments, the needle-free injector may be configured to be adjustable according to either an injection pressure and/or a nozzle orifice diameter in order to achieve injection at the desired penetration depth. In various embodiments, the needle-free injector may be configured to inject the fluid injectate according to a combined injection relationship that is both substantially linear between the adjusted pressure and the desired penetration depth and between the nozzle orifice diameter and the desired penetration depth. Other embodiments may be described and claimed. | 11-14-2013 |
20110319860 | INTRADERMAL INJECTION DEVICE - Embodiments herein relate to the field of injections, for instance needle-free injections, and more specifically, to methods and apparatus for spring-driven intramuscular and intradermal injections. Provided in some embodiments are needle-free injectors adapted to deliver intradermal injections, as well as vial adaptors that are adapted to function as spacers when used with a needle-free injection device. | 12-29-2011 |
20110315269 | HIGH WORKLOAD INJECTION SYSTEM - A filling device for a needle-free injector system is provided that is adapted to sterilely deliver a predetermined amount of an injectate from a vial to a plurality of cartridges. The filling device normally includes a single-use fluid path disposed between the vial and a receiving cartridge. The fluid path may include a vial connector adapted to couple to a vial, a filler head, and a conduit connecting the vial connector and filler head. The filling device typically further includes a pump coupled to the fluid path and adapted to propel the injectate from the vial to the receiving cartridge, and a cartridge-advancing element. Activation of the cartridge-advancing element is adapted to sequentially advance empty cartridges into a position opposite the filler head. Also provided are disposable fluid path kits and methods of using the filling device. | 12-29-2011 |
20100076374 | INJECTION DEVICE PLUNGER AUTO-DISABLE - A nozzle assembly for a needle-free injection device. The nozzle assembly includes a nozzle body including an injectate chamber and one or more outlet orifices and a plunger configured to move through the injectate chamber toward the one or more outlet orifices. In some embodiments, the plunger includes a first portion and a second portion removably joined by a frangible region. In some embodiments, the plunger includes extensions configured to couple the plunger to a drive assembly of a needle-free injection device. | 03-25-2010 |
20100069831 | NEEDLE-FREE INJECTION SYSTEM - A needle-free injection device in which a gas cartridge or other source of pressurized gas is used to advance a piston and forcibly expel injectable fluid out through an injection orifice. When a gas cartridge is used, the gas cartridge may be moveable from an initial position to an actuating position in which gas is released to drive the injection, and a recoil inhibitor may be employed to prevent the gas cartridge from moving back to the initial position. A gas cartridge seal may be disposed on the gas cartridge and moveable with the gas cartridge to seal the gas cartridge against an interior wall of a gas cartridge housing. The needle-free injection device may also be configured so that sealing is compromised upon full advancement of the piston, so as to de-pressurize the device after delivery of an injection. | 03-18-2010 |
20100025503 | NEEDLE-FREE INJECTION DEVICE WITH NOZZLE AUTO-DISABLE - A nozzle assembly for a needle-free injection device. The nozzle assembly includes a nozzle body including an injectate chamber and one or more outlet orifices and a plunger configured to move through the injectate chamber toward the one or more outlet orifices. In some embodiments, the plunger includes a first portion and a second portion removably joined by a frangible region. In some embodiments, the plunger includes extensions configured to couple the plunger to a drive assembly of a needle-free injection device. | 02-04-2010 |
20090247940 | TRIGGERING MECHANISM FOR A NEEDLE-FREE INJECTOR - Needle-free hypodermic jet injection devices having an actuation system to effect an injection from a drug delivery system. The actuation system includes an injection force assembly adapted to transmit a driving force to the drug delivery system. The actuation system further includes a trigger assembly adapted to alter the actuation system between a plurality of configurations including a fired configuration in which the injection force assembly transmits a driving force to the drug delivery system. In some embodiments, the device has a recoil restriction system including a restriction member adapted to couple the recoil restriction system to the trigger assembly and a recoil member coupled to the injection force assembly and movable relative to the restriction member. The restriction member limits movement of the recoil member once the recoil member moves a predetermined distance relative to the restriction member. | 10-01-2009 |
20090156992 | NEEDLE-FREE INJECTION DEVICE AND PRIMING SYSTEM - Needle-free injection devices having a delivery system to effect an injection and a body configured to house the delivery system. The delivery system includes an injectate assembly adapted to house a volume of liquid and a drive assembly adapted to expel the volume of liquid from the injectate assembly. In some embodiments, the drive assembly includes a pair of parallel springs. The device further includes a priming system adapted to prepare the device for delivery of an injection. The priming system includes a force-preparation assembly adapted to selectively arrange the drive assembly to provide the drive force to the injectate assembly. In some embodiments, the priming system includes a locking assembly adapted to releasably retain the injectate assembly relative to the body. In some embodiments, the priming system includes a dosing assembly adapted to selectively draw a volume of liquid into the injectate assembly. | 06-18-2009 |
20090137949 | NEEDLE-FREE INJECTION DEVICE WITH NOZZLE AUTO-DISABLE - A nozzle assembly for a needle-free injection device. The nozzle assembly includes a nozzle body including an injectate chamber and one or more outlet orifices and a plunger configured to move through the injectate chamber toward the one or more outlet orifices. In some embodiments, the plunger includes a first portion and a second portion removably joined by a frangible region. In some embodiments, the plunger includes extensions configured to couple the plunger to a drive assembly of a needle-free injection device. | 05-28-2009 |
20090137948 | NEEDLE-FREE INJECTION DEVICE WITH AUTO-DISABLE - Needle-free injection devices having a body, an actuation system, and a delivery system including a drive assembly and configured to receive a nozzle assembly. In some embodiments, the drive assembly includes a spring and a support member configured to restrict movement of the spring in a direction non-parallel to a central axis of the spring. In some embodiments, the drive assembly includes a transmission assembly configured to couple a drive source with the actuation system upon engagement of a nozzle assembly with the drive assembly. In some embodiments, the body is configured to acoustically seal an interface between the delivery system and the actuation system. In some embodiments, the body includes a gripping member selectively extendable from the body. | 05-28-2009 |