Bayer Intellectual Property GmbH Patent applications |
Patent application number | Title | Published |
20160130230 | SUBSTITUTED DICYANOPYRIDINES AND USE THEREOF - The present application relates to novel substituted dicyanopyridines, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, preferably for the treatment and/or prophylaxis of cardiovascular disorders. | 05-12-2016 |
20160051518 | BISARYL-BONDED ARYLTRIAZOLONES AND USE THEREOF - The present application relates to novel bisaryl-linked 5-aryl-1,2,4-triazolone derivatives, to processes for preparing them, to their use alone or in combinations for the treatment and/or prevention of diseases and also to their use for the production of medicaments for the treatment and/or prevention of diseases, more particularly for the treatment and/or prevention of cardiovascular disorders. | 02-25-2016 |
20150368250 | IMIDAZOPYRIDAZINES AS AKT KINASE INHIBITORS - Imidazopyridazines of formula (I) | 12-24-2015 |
20150344370 | MATTE FLAME-RETARDANT ARTICLE WITH HIGH TRANSMISSION - The invention relates to a coated article containing a) a substrate (S) with a transmission of at least 88% (measured according to ASTM E 1348 with 3 mm layer thickness and a wavelength of 550 nm), comprising a substrate layer consisting of a thermoplastic polymer containing a flame-retardant agent, and b) a scratch-resistant coating (K) containing silica micro-particles on the substrate, said coating (K) containing 0.2 to 1.8 wt. %. silica micro-particles relative to the solids content thereof. The invention further relates to the production of such coated articles and the use thereof, especially for producing flat screens. | 12-03-2015 |
20150335658 | UV STABLE TRANSDERMAL PLASTER - The invention relates to a UV stable transdermal therapeutic system (TTS) consisting of a back layer, at least one matrix containing an active substance and optionally, a withdrawal film and an UV-radiation absorber. An adhesive layer containing said UV-radiation absorber is arranged between the back layer and the matrix containing an active substance which is distant as much as possible from a surface, a separation layer is arranged between the adhesive layer containing said UV-radiation absorber and the matrix containing an active substance, which is as remote as possible from the surface which is impermeable to the active substance and UV-radiation absorber. The inventive transdermal therapeutic system exhibits a high stability and is devoid of inconveniences of existing TTS containing a light-sensitive substance. | 11-26-2015 |
20150328318 | Stabilization of Vitamin B12 - The invention relates to preparations comprising vitamin B | 11-19-2015 |
20150306102 | SUBSTITUTED PYRAZOLOPYRIMIDINES AS AKT KINASE INHIBITORS - Compounds of formula (I) which are effective inhibitors of the Pi3K/Akt pathway, processes for their production and their use as pharmaceuticals. | 10-29-2015 |
20150299428 | POLYCARBONATE COMPOSITION WITH IMPROVED OPTICAL PROPERTIES - The invention relates to a polycarbonate composition and copolycarbonate composition ((co)polycarbonates) with improved optical properties of the mouldings produced therefrom. | 10-22-2015 |
20150292167 | METHOD FOR COVERING A BALLAST BED WITH FOAM IN A RAILWAY TRACK SYSTEM - A method is provided for foaming a ballast bed of a railway track wherein the railway track comprises sleepers positioned on the ballast bed and rails positioned on the sleepers, wherein the rails are covered at least in a partial area along a region of the ballast bed to be foamed, and a foaming agent is introduced into the ballast bed whilst the rails are covered, wherein the ballast bed has in a sleeper bay defined by two successive sleepers an upper side facing against the gravitational direction, and the ballast bed is heaped up so that the upper side of the ballast bed reaches at least up to an underneath side of the sleeper facing in the gravitational direction. | 10-15-2015 |
20150291512 | METHOD FOR PRODUCING ISOCYANATES - The invention relates to a method for preparing isocyanates by phosgenating the corresponding amines, wherein low-boiling secondary components, excess phosgene, and the co-product hydrogen chloride are separated from the crude liquid isocyanate stream, which is obtained after the phosgenation has occurred, within a maximum of 60 minutes, and wherein the crude liquid isocyanate stream is not exposed to temperatures above 250° C. until said separation. | 10-15-2015 |
20150274754 | SUBSTITUTED ANNULATED TRIAZINES AND USE THEREOF - The present application relates to novel substituted fused pyrimidines and triazines, to processes for their preparation, to their use alone or in combinations for the treatment and/or prophylaxis of diseases, and to their use for producing medicaments for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of cardiovascular disorders. | 10-01-2015 |
20150210683 | SUBSTITUTED TRIAZOLOPYRIDINES AND THEIR USE AS TTK INHIBITORS - The present invention relates to substituted triazolopyridine compounds of general formula (I): | 07-30-2015 |
20150189882 | ACTIVE INGREDIENT COMBINATIONS HAVING INSECTICIDAL AND ACARICIDAL PROPERTIES - The novel active ingredient combinations which comprise a compound of the formula (I) in combination with further active insecticidal ingredients or biological control agents are very suitable for control of animal pests such as insects and/or unwanted acarids and indirectly improve plant health. The compound of the formula (I) in combination with further active insecticidal ingredients or biological control agents can be used for reducing overall damage of plants and plant parts as well as losses in harvested fruits or vegetables caused by insects, nematodes and phytopathogens. | 07-09-2015 |
20150182540 | DROSPIRENONE FOR HORMONE REPLACEMENT THERAPY - A pharmaceutical composition comprising as a first active ingredient an estrogen, such as estradiol or estradiol valerate, in sufficient amounts to treat disorders and symptoms associated with deficient endogenous levels of estrogen in women, and as a second active ingredient 6β,7β;15β;16β-dimethylene-3-oxo-17α-preg-4-ene-21,17-carbolactone (drospirenone, DRSP) in sufficient amounts to protect the endometrium from the adverse effects of estrogen is useful for, amongst others, treating peri-menopausal, menopausal and post-menopausal women. This composition may be used for hormone replacement therapy and may be administered as a multi-phased pharmaceutical preparation. This combination therapy may comprise continuous, sequential or interrupted administration, or combinations thereof, of DRSP and estrogen, each optionally in micronized form. | 07-02-2015 |
20150150827 | MULTI-LAYERED TRANSDERMAL SYSTEM WITH TRIAZINE UV ABSORBER - The UV-stable solid transdermal therapeutic system (TTS) with UV absorber for photosensitive active pharmaceutical ingredients has a backing layer ( | 06-04-2015 |
20150125703 | FIBER-REINFORCED POLYISOCYANURATE COMPONENT AND A METHOD FOR PRODUCTION THEREOF - The present invention relates to fibre-composite components that are produced by impregnating fibres with a reaction resin mixture of polyisocyanates, polyols, trimersation catalysts and optionally additives, and to a method for production thereof. | 05-07-2015 |
20150101518 | SEEDING MACHINE AND SEEDING METHOD - The invention relates to a seeding machine ( | 04-16-2015 |
20150094308 | SUBSTITUTED TRIAZINE DERIVATIVES AND USE THEREOF AS STIMULATORS OF SOLUBLE GUANYLATE CYCLASE - The present application relates to novel substituted fused pyrimidines, to processes for their preparation, to their use alone or in combinations for the treatment and/or prophylaxis of diseases, and to their use for producing medicaments for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of cardiovascular disorders. | 04-02-2015 |
20150094205 | 5-AMINOPYRIMIDINE DERIVATIVES AND USE THEREOF FOR COMBATING UNDESIRED PLANT GROWTH - What is described are compounds of the general formula (I) and agrochemically acceptable salts thereof | 04-02-2015 |
20150087631 | AMINO-SUBSTITUTED IMIDAZOPYRIDAZINES - The present invention relates to amino-substituted imidazopyridazine compounds of general formula (I), in which A, R1, R2, R3, R4, R5 and n are as defined in the claims, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyper-proliferative and/or angiogenesis disorder, as a sole agent or in combination with other active ingredients. | 03-26-2015 |
20150082495 | RNAi FOR THE CONTROL OF FUNGI AND OOMYCETES BY INHIBITING SACCHAROPINE DEHYDROGENASE GENE - The present invention relates to control of plant pathogens, particularly fungi or oomycetes, by inhibiting one or more biological functions, particularly by inhibiting saccharopine dehydrogenase gene(s) using RNA interference. The invention provides methods and compositions using RNA interference of plant pathogens target genes for such control. The invention is also directed to methods for making transgenic plants tolerant to said plant pathogens, and to transgenic plants and seeds generated thereof. | 03-19-2015 |
20150080438 | 6,7-Dihydro-5H-benzo[7]annulene derivatives, processes for their preparation, pharmaceutical products comprising them and their use for preparing medicaments - The invention relates to selective oestrogen receptor modulators (SERMs) and to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular of bleeding disorders, osteoporosis, endometriosis, myomata, hormone-dependent tumours, for hormone replacement therapy and for contraception. | 03-19-2015 |
20150080414 | SUBSTITUTED 5-FLUORO-1H-PYRAZOLOPYRIDINES AND THEIR USE - The present application relates to novel substituted 5-fluoro-1H-pyrazolopyridines, to processes for their preparation, to their use alone or in combinations for the treatment and/or prophylaxis of diseases, and to their use for producing medicaments for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of cardiovascular disorders. | 03-19-2015 |
20150080352 | AQUEOUS POLYURETHANE DISPERSION IN THE TREATMENT OF ACNE - The present invention describes a surprising effect of an aqueous polyurethane dispersion on the efficacy of active ingredients in the anti-acne treatment. The aqueous polyurethane dispersion was able to reduce irritation and substantially enhance efficacy of the salicylic acid and/or salicylic acid derivative in the topical anti-acne serum. | 03-19-2015 |
20150073180 | METHOD FOR CONTINUOUS PRODUCTION OF NITROBENZENE - The invention relates to a method for producing nitrobenzene, in which crude nitrobenzene is first produced by nitrating benzene and said crude nitrobenzene is then washed in succession in at least one acid wash, in at least one alkaline wash and in at least one neutral wash, at least one additional wash with an aqueous solution of a potassium salt being interposed between the last alkaline wash and the first neutral wash. | 03-12-2015 |
20150065533 | Benzyl-substituted carbamates and use thereof - The present application relates to novel benzyl-substituted carbamates, to processes for their preparation, to their use, alone or in combinations, for the treatment and/or prophylaxis of diseases and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, especially for the treatment and/or prophylaxis of cardiovascular disorders. | 03-05-2015 |
20150057318 | USE OF SUCCINATE DEHYDROGENASE INHIBITORS (SDHIS) FOR CONTROLLING WOOD DISEASES IN GRAPE - The invention relates to the use of succinate dehydrogenase SDH inhibitors (SDHIs), in particular bixafen, penflufen or fluopyram for controlling wood diseases in grape, to a method for treating plants or plant parts for controlling wood diseases in grape and to a method for controlling wood diseases in grape plants and plant parts, and in plants which grow from the seedlings, grafts and cuttings, by treating them with SDHIs. | 02-26-2015 |
20150051407 | PROCESS FOR PREPARING CIS-ALKOXY-SUBSTITUTED SPIROCYCLIC PHENYLACETYLAMINO ACID ESTERS AND CIS- ALKOXY-SUBSTITUTED SPIROCYCLIC 1H- PYRROLIDINE-2,4-DIONE DERIVATIVES - The present invention relates to a novel process for preparing cis-alkoxy-substituted spirocyclic phenylacetylamino acid esters and cis-alkoxy-substituted spirocyclic 1H-pyrrolidine-2,4-dione derivatives, and also to novel intermediates and starting materials which are produced and/or used in the process according to the invention. | 02-19-2015 |
20150051301 | METHOD FOR PRODUCING A HARD POLYURETHANE-POLYISOCYANURATE FOAMED MATERIAL - The present invention relates to a process for producing a rigid polyurethane-polyisocyanurate foam C, comprising the step of reacting (i) an isocyanate-terminated prepolymer B with (ii) an activator component A comprising at least one trimerisation catalyst A1 and at least one blowing agent A3 in a reaction mixture to form a foam, characterised in that—there is used an isocyanate-terminated prepolymer B obtained from a reaction of an isocyanate B1 having a mean isocyanate functionality of from ≧2.3 to ≦2.9 with a polyol component B2, and—the activator component A comprises water as the blowing agent A3 in an amount of from ≧5 wt. % to ≦50 wt. %,—the isocyanate index in the reaction mixture is in a range of from ≧400 to ≦500, and—the isocyanate content of the prepolymer B is in a range of from ≧21 wt. % to ≦30 wt. %, based on the total mass of the prepolymer B, and—wherein in the reaction of the prepolymer B and the activator component A a conversion contribution to polyisocyanurate of ≦75% is achieved. Rigid foams C so produced have good flame retarding properties while at the same time having good insulating properties and stability properties. The present invention relates further to a rigid polyisocyanurate foam C produced by the process according to the invention, to the use of such a rigid polyisocyanurate foam C in the production of heat-insulating structural components, and to a heat-insulating structural component comprising such a rigid polyurethane-polyisocyanurate foam. | 02-19-2015 |
20150051160 | TYROSINE BASED LINKERS FOR THE RELEASABLE CONNECTION OF PEPTIDES - The invention relates to novel tyrosine based linkers that allow the releasable connection of peptides or proteins with other molecular entities, e.g. polyethylene glycol, to processes for their preparation and their use for preparing medicaments for the treatment and/or prophylaxis of diseases. | 02-19-2015 |
20150050503 | STORAGE STABLE RESIN FILMS AND FIBRE COMPOSITE COMPONENTS PRODUCED THEREFROM - The invention relates to a storage-stable resin film based on polyurethane systems having a very high characteristic number and fibre-composite components (composite components, moulded bodies) produced therefrom by compressing the resin film, in combination with fibre-reinforced materials such as woven fabrics and fleece, at high temperatures and under pressure, and to a method for the production thereof. | 02-19-2015 |
20150047705 | USE OF UV-RADIATION-HARDENABLE POLYURETHANE RESINS FOR PRODUCING SOLAR LAMINATES - The present invention relates to the use of a radiation-hardenable resin composition for producing solar laminates, a method for creating a solar laminate using the resin composition according to the invention, and a solar laminate that can be produced using this method. | 02-19-2015 |
20150038485 | HETEROCYCLYL AMINOIMIDAZOPYRIDAZINES - The present invention relates to heterocyclyl aminoimidazopyridazine compounds of general formula (I): in which A, R1, R2, R3 and R4 are as defined in the claims, to methods of preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyper-proliferative and/or angiogenesis disorder, as a sole agent or in combination with other active ingredients. | 02-05-2015 |
20150037415 | PROCESS FOR THE PREPARATION OF A SOLID, ORALLY ADMINISTRABLE PHARMACEUTICAL COMPOSITION - The present invention relates to a process for the preparation of a solid, orally administrable pharmaceutical composition, comprising 5-chloro-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl}-methyl)-2-thiophenecarboxamide in hydrophilized form, and its use for the prophylaxis and/or treatment of diseases. | 02-05-2015 |
20150031676 | SUBSTITUTED BENZOTHIENYL-PYRROLOTRIAZINES AND USES THEREOF - This invention relates to novel substituted 5-(1-benzothiophen-2-yl)pyrrolo[2,1-f][1,2,4]triazin-4-amine derivatives having protein tyrosine kinase inhibitory activities, to processes for the preparation of such compounds, to pharmaceutical compositions containing such compounds, and to the use of such compounds or compositions for treating proliferative disorders, in particular cancer and tumor diseases. | 01-29-2015 |
20150025253 | PESTICIDAL ARYLPYRROLIDINES - Arylpyrrolidines of formula (I): | 01-22-2015 |
20150024935 | HETEROARYLPIPERIDINE AND PIPERAZINE DERIVATIVES AS FUNGICIDES - Heteroarylpiperidine and -piperazine derivatives of the formula (I) | 01-22-2015 |
20150018561 | CF3O-CONTAINING ENAMINOKETONES AND THEIR UTILIZATION FOR THE PREPARATION OF CF3O-CONTAINING PYRAZOLES - The present invention pertains to novel enaminoketones containing a CF | 01-15-2015 |
20150011689 | UV-STABILIZED, GLASS-FIBER REINFORCED, FLAME-RETARDANT POLYCARBONATES FOR THE EE AND IT SECTOR - The present invention relates to glass fibre-reinforced polycarbonate compositions of high rigidity and improved thermal and rheological properties in combination with improved flameproofing properties and a significantly increased Vicat temperature. The present invention furthermore relates to the use of the compositions according to the invention for the production of thin-walled housing parts or switch boxes in the EE (electrical/electronics) and IT (information technology) sector. | 01-08-2015 |
20150011394 | USE OF HOST DEFENSE INDUCERS FOR CONTROLLING BACTERIAL HARMFUL ORGANISMS IN USEFUL PLANTS - The present invention relates to the use of host defense inducers for controlling selected bacterial harmful organisms in useful plants, wherein the bacterial harmful organisms are selected from the group consisting of | 01-08-2015 |
20150009009 | CONDUCTIVE POLYMER FUSE - The present invention provides a conductive polymer fuse comprising a substrate having printed thereon poly(3,4-ethylenedioxythiophene)/poly(styrene-sulfonate) and one or more high conductivity connections, wherein the conductive fuse is encapsulated with an encapsulant. Methods for producing the inventive conductive polymer fuses are also provided. Such conductive polymer fuses may find use in improving printed electronic devices by protecting those devices against short circuits. | 01-08-2015 |
20140378514 | FUNGICIDE COMPOSITIONS COMPRISING FLUOPYRAM, AT LEAST ONE SUCCINATE DEHYDROGENASE (SDH) INHIBITOR AND OPTIONALLY AT LEAST ONE TRIAZOLE FUNGICIDE - The present invention relates to novel fungicide compositions comprising (A) fluopyram, (B) at least one further succinate dehydrogenase (SDH) inhibitor and optionally further (C) at least one triazole fungicide, whereas the invention especially comprises such novel fungicide compositions of (A) fluopyram, (B) bixafen and (C) at least one triazole fungicide, which is preferably prothioconazole. The present invention also relates to the use of such novel fungicide compositions for improving growth in crops, comprising preventively and/or curatively controlling pathogenic fungi and/or nematodes, resistance management, and improving plant physiology effects by enhancing root growth, improving greening, improving water use efficiency, improving nitrogen-use efficacy, delaying senescence and enhancing yield. | 12-25-2014 |
20140378306 | USE OF 5-PHENYL- OR 5-BENZYL-2 ISOXAZOLINE-3 CARBOXYLATES FOR IMPROVING PLANT YIELD - Compound (A) can be used for increasing the yield of useful plants or crop plants with respect to their harvested plant organs, wherein the Compound (A) is selected from compounds of the formula (I) or salts thereof, | 12-25-2014 |
20140375170 | ELECTROMECHANICAL TRANSDUCER DEVICE - The invention relates to an electromechanical transducer device ( | 12-25-2014 |
20140370770 | PROCESS FOR THE COATING OF TEXTILES - The present invention relates to a process for the production of coated textiles in which a textile substrate is firstly brought into contact with an aqueous dispersion comprising at least one inorganic salt and at least one modified cellulose. | 12-18-2014 |
20140370267 | COMPOSITE ELEMENTS WITH IMPROVED DIMENSIONAL STABILITY - The present invention relates to a polyurethane/polyisocyanurate foam with improved dimensional stability. It relates further to the use thereof in the production of metal composite elements, to metal composite elements produced therewith, and to a method for producing metal composite elements. | 12-18-2014 |
20140364456 | HETEROCYCLYLPYRI(MI)DINYLPYRAZOLE - Heterocyclylpyri(mi)dinylpyrazole of the formula (I), in which R | 12-11-2014 |
20140357767 | POLYCARBONATE COMPOSITIONS WITH IMPROVED MELT STABILITY - The invention relates to polycarbonate compositions and copolycarbonate compositions with improved melt stability, the preparation thereof and the use thereof for the production of mouldings and mouldings obtainable therefrom, wherein the compositions contain a polycarbonate or copolycarbonate containing bisphenol A, and at least one phosphorus compound of the formulae (1) and (2), wherein R1 and R2 independently of each other and among one another are chosen from the group which includes branched alkyl radicals, aryl radicals and substituted aryl radicals. | 12-04-2014 |
20140350206 | THERMOPLASTIC POLYURETHANE FOR PRODUCING HYDROPHILIC FIBERS - The invention relates to a thermoplastic polyurethane that can be obtained by reacting at least the following components: an isocyanate having two isocyanate groups, a first poly(ethylene glycol)polyether diol of the structure (HO—(CH2-CH2-O)x-H) having two isocyanate-reactive groups and a number-average molecular weight Mn>=6000 and <=16000 g/mol, a second poly(ethylene glycol)polyether diol of the structure (HO—(CH2-CH2-O)x-H) having two isocyanate-reactive groups and a number-average molecular weight Mn that corresponds to up to 80% of the number-average molecular weight Mn of the first poly(ethylene glycol)polyether diol B1), a chain extender having two isocyanate-reactive groups and a number-average molecular weight Mn>=60 and <600 g/mol, optionally a catalyst, and optionally auxiliary agents and additives, wherein the equivalent ratio of isocyanate A); to poly(ethylene glycol)polyether diols B1) and B2) lies between 1.5:1.0 and 10.0:1.0 and the NCO index, calculated from the quotient of the equivalent ratios of the isocyanate groups multiplied by 100 and the total of the isocyanate-reactive groups, is 90 to 105. The invention further relates to a method for producing the thermoplastic polyurethane according to the invention and to a thermoplastic polyurethane that can be obtained as per the method according to the invention. | 11-27-2014 |
20140350020 | RING-FUSED PYRIMIDINES AND TRIAZINES AND USE THEREOF FOR THE TREATMENT AND/OR PROPHYLAXIS OF CARDIOVASCULAR DISEASES - The present application relates to novel fused pyrimidines and triazines, to processes for their preparation, to their use alone or in combinations for the treatment and/or prophylaxis of diseases and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of cardiovascular disorders. | 11-27-2014 |
20140350008 | 2-HETEROARYL CARBOXAMIDES - The invention relates to novel 2-heteroaryl carboxamides and to the use thereof for producing medicaments for the treatment and/or prophylaxis of diseases and for improving perception, concentration, learning and/or memory. | 11-27-2014 |
20140349346 | NEW ACTINOMYCETE INTEGRATIVE AND CONJUGATIVE ELEMENT FROM ACTINOPLANES SP. SE50/110 AS PLASMID FOR GENETIC TRANSFORMATION OF RELATED ACTINOBACTERIA - The present invention is directed to an innate DNA sequence within the complete genome sequence of | 11-27-2014 |
20140336233 | USE OF TETRAMIC ACID DERIVATIVES FOR CONTROLLING PATHOGENS BY FOLIAR APPLICATION - Compounds of the formulae (I) and (II) for controlling pathogens by foliar application. | 11-13-2014 |
20140330051 | CATALYTIC GAS PHASE FLUORINATION OF 1,1,2-TRICHLOROETHANE AND/OR 1,2-DICHLOROETHENE TO PRODUCE 1-CHLORO-2,2-DIFLUOROETHANE - The invention is directed to a catalyst for the gas phase fluorination of 1,1,2-trichloroethane and/or 1,2-dichloroethene with HF to give 1-chloro-2,2-difluoroethane which catalyst is prepared by co-depositing FeCl | 11-06-2014 |
20140329965 | PROCESS FOR PREPARING PLASTICS WITH IMPROVED HYDROLYSIS STABILITY, THE PLASTICS PREPARED FROM THE SAME AND USES THEREOF - The present invention relates to a process for preparing plastics with improved hydrolysis stability, comprising a step of adding 0.05-5 wt. % perchlorate salt which is based on 100 wt. % of the plastics, as a raw material to prepare the plastics. The present invention also relates to the plastics prepared from the process and use thereof. | 11-06-2014 |
20140329797 | SUBSTITUTED OXADIAZOLYL PYRIDINONES AND OXADIAZOLYL PYRIDAZINONES AS HIF INHIBITORS - The present application relates to novel substituted 5-(1,2,4-oxadiazol-5-yl)pyridin-2-ones and 6-(1,2,4-oxadiazol-5-yl)pyridazin-3-ones, to processes for their preparation, to their use for the treatment and/or prevention of diseases and to their use for producing medicaments for treatment and/or prevention of diseases, in particular for treatment and/or prevention of hyperproliferative and angiogenic diseases and those diseases which arise from metabolic adaptation to hypoxic states. Such treatments can be effected in the form of monotherapy or else in combination with other medicaments or further therapeutic measures. | 11-06-2014 |
20140323670 | METHOD FOR PRODUCING POLYETHER CARBONATE POLYOLS - The present invention relates to a method for producing polyether carbonate polyols by way of the catalytic addition of carbon dioxide and alkylene oxides to H-functional starter compounds in the presence of double metal cyanide (DMC) catalyser that was activated in the presence of cyclic anhydride. | 10-30-2014 |
20140323605 | STABLE EMULSIONS AND THEIR USE IN THE PRODUCTION OF FOAMS BASED ON ISOCYANATE - The invention relates to stable emulsions for the production of foams based on isocyanate, at least comprising three polyols A1a, A1b and A1c as well as at least one physical blowing agent T, wherein A1a is a polyether polyol obtained by addition of epoxides to starter compounds selected from carbohydrates and di- or higher-functional alcohols, A1b is a polyether polyol started on an aromatic amine, and A1c is a polyester polyol obtained by esterification of a polycarboxylic acid component and a polyalcohol component, wherein the total amount of aromatic dicarboxylic acid derivatives used in the esterification, calculated on the basis of the free aromatic dicarboxylic acids and based on the total mass of polyalcohol component and polycarboxylic acid component, is less than or equal to 48.5% by mass. | 10-30-2014 |
20140323540 | USE OF A DITHIINO-TETRACARBOXAMIDE FOR THE PROTECTION OF HARVESTED PRODUCTS AGAINST PHYTOPATHOGENIC FUNGI - The present invention relates to methods for the protection of harvested fruits, cutflowers or vegetables against decay caused by certain storage diseases or disorders expressed in storage conditions, which fruits, cutflowers or vegetables have been treated pre-harvest with dithiino-tetracarboximides for formula (I). In particular the invention relates to the application of dithiino-tetracarboximides of formula (I) before harvest to protect harvested fruit, cutflowers or vegetables against phytopathogenic fungi. | 10-30-2014 |
20140323525 | Fungicidal Active Substance Combinations Containing Trifloxystrobin - What are described are novel active compound combinations comprising a known oxime ether derivative (trifloxystrobin) and imidacloprid, which combinations are highly suitable for controlling phytopathogenic fungi and insects. | 10-30-2014 |
20140322544 | COMPOSITE ELEMENTS COMPOSED FROM THERMOPLASTIC POLYMERS AND POLYURETHANES, AND PROCESS FOR PRODUCTION THEREOF - The invention relates to composite elements comprising a thermoplastic polymer and an adjacent polyurethane bonded thereto, to a process for production thereof and to the use thereof. | 10-30-2014 |
20140322509 | MULTI-LAYER BODIES MADE OF POLYCARBONATE WITH A DEEP GLOSS EFFECT - The present invention relates to dark multilayer bodies made from polycarbonate, which are characterised by a glass-like deep-gloss effect on the surface. The invention also relates to a method for producing these multilayer bodies. The multilayer bodies are preferably synthesised from polycarbonate or polycarbonate blends. The polycarbonate blends can contain further polymers such as for example elastomers or graft polymers, or further thermoplastics such as polyesters for example. The invention also relates to the use of the multilayer bodies according to the invention as panels for vehicle parts or as frame parts for multimedia housings. | 10-30-2014 |
20140322220 | Anti-FGFR2 Antibodies and Uses Thereof - The present invention provides antibodies, or antigen-binding antibody fragments thereof, or variants thereof which reduce the cell surface expression of FGFR2 after binding to FGFR2 in both cells overexpressing FGFR2 and cells expressing mutated FGFR2. Also provided are antibody-based therapies for FGFR2-related diseases or conditions such as cancer. Antibodies of the invention also can be used in the diagnostics field. The invention also provides nucleic acid sequences encoding the foregoing antibodies, vectors containing the same, pharmaceutical compositions and kits with instructions for use. | 10-30-2014 |
20140319431 | ELECTRICALLY CONDUCTIVE PRINTABLE COMPOSITION - An electrically conductive printable composition comprises silver particles, a dispersing agent, a solvent, a first surfactant, comprising a hydrocarbon based surfactant, and a second surfactant, comprising a fluoro-based surfactant. | 10-30-2014 |
20140318395 | SCREEN PRINTING METHOD USING PRINTING INK WHICH REACTS TO FORM A POLYURETHANE POLYMER - The invention relates to a method for printing objects, comprising the step of application of a printing ink by means of screen printing, wherein the printing ink comprises a polyisocyanate A) and/or a polyisocyanate prepolymer B), an at least difunctional compound C) which is reactive towards isocyanate groups and furthermore a catalyst D) which cap be activated by increasing the temperature. It also relates to the use of a corresponding reaction, mixture as a printing ink in screen printing processes and to an electromechanical converter having a polymer layer produced, by a method according to the invention. | 10-30-2014 |
20140317951 | DEVICE FOR FILTRATION, DRYING AND STORAGE - The invention relates to a device for filtration, drying and storage of solids from a suspension (FDS unit) and a method carried out in this system for the downstream processing of a solids suspension, in particular of crystallizable therapeutic proteins or active ingredients. The FDS unit, designed for use as a disposable system, is a device with which active ingredient crystals can be gently and safely filtered, dried, stored and reconstituted in a closed process procedure, i.e. without intermediate opening or transfer. | 10-30-2014 |
20140316157 | ETHERIFIED LACTATE ESTERS, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF FOR ENHANCING THE EFFECT OF PLANT PROTECTING AGENTS - The invention relates to etherified lactate esters of formula (I), in which R represents alkyl and RI an alkoxylated alkyl radical and to the use thereof for enhancing the effect of plant protecting agents. | 10-23-2014 |
20140316051 | AQUEOUS POLYACRYLATE COPOLYMER DISPERSIONS WITH HIGH OH GROUP CONTENT - The present invention relates to aqueous secondary copolymer dispersion comprising a copolymer (P) synthesized from a mixture of free-radically polymerizable monomers (M) comprising: (M1) cycloaliphatic esters of acrylic and/or methylacrylic acid; (M3) hydroxy-functional, free-radically polymerizable monomers; (M4) carboxyl-functional, free-radically polymerizable monomers and (M5) hydroxyl- and carboxyl-free (meth)acrylic esters having C1 to C12 hydrocarbon radicals in the alcohol moiety and/or vinylaromatics, wherein the mixture further comprises polyols (PO) selected from the group of polyester polyols and/or polycarbonate polyols, the polyols having an average hydroxyl group functionality of at least 2. The invention also relates to a method for the production of such a dispersion, to the use of the dispersion as a coating and as a binder in 2K polyurethane coatings. | 10-23-2014 |
20140316050 | LOW-SOLVENT POLYACRYLATE COPOLYMER DISPERSIONS - The present invention relates to an aqueous secondary copolymer dispersion comprising a copolymer (P) synthesized from a mixture of free-radically polymerizable monomers (M) comprising (M1) cycloaliphatic esters of acrylic and/or methylacrylic acid; (M2) vinyl esters of aliphatic carboxylic acids; (M3) hydroxy-functional, free-radically polymerizable monomers; (M4) carboxyl-functional, free-radically polymerizable monomers and (M5) hydroxyl- and carboxyl-free (meth)acrylic esters having C1 to C12 hydrocarbon radicals in the alcohol moiety and/or vinylaromatics. The mixture further comprises glycidyl esters of aliphatic carboxylic acids. The invention also relates to a method for the production of such a dispersion, to the use of the dispersion as a coating and as a binder in 2K polyurethane coatings. | 10-23-2014 |
20140315958 | 4-[4-(AMINO)-3-FLUOROPHENOXY]-N-METHYLPYRIDINE-2-CARBOXAMIDE MONOHYDRATE - The present invention relates to 4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)-3-fluorophenoxy]-N-methylpyridine-2-carboxamide monohydrate, to processes for its preparation, to pharmaceutical compositions comprising it and to its use in the control of disorders. | 10-23-2014 |
20140315906 | 4-ARYL-N-PHENYL-1,3,5-TRIAZIN-2-AMINES CONTAINING A SULFOXIMINE GROUP - The present invention relates to 4-aryl-N-phenyl-1,3,5-triazin-2-amines containing a sulfoximine group of general formula (I) or (Ia) as described and defined herein, and methods for their preparation, their use for the treatment and/or prophylaxis of disorders, in particular of hyper-proliferative disorders and/or virally induced infectious diseases and/or of cardiovascular diseases. The invention further relates to intermediate compounds useful in the preparation of said compounds of general formula (I) or (Ia). | 10-23-2014 |
20140312737 | LAYER COMPOSITE COMPRISING ELECTROACTIVE LAYERS - The invention relates to a multi-layer composite ( | 10-23-2014 |
20140309457 | CATALYST AND METHOD FOR PRODUCING AROMATIC AMINES IN THE GAS PHASE - The present invention relates to a catalyst comprising a ceramic support with a BET surface area of less than 40 m | 10-16-2014 |
20140308492 | SOUND-ABSORBING COMPOSITE AND ITS USE - The present invention relates to composite elements comprising a layer of open-cell, hard, isocyanate-based foam and at least one further layer of isocyanate-based foam, and to their use for sound absorption. | 10-16-2014 |
20140305036 | FUNCTIONAL POLYTUNNELS, IN PARTICULAR SELF-ERECTING STRUCTURES AND PROGRAMMING METHODS THEREFOR - A device comprising a planar material and at least one support element which is connected to the planar material, wherein the at least one support element comprises at least one shape memory polymer, such that the device has a substantially flat shape in a first configuration of the at least one shape-memory polymer and a substantially domed shape in a second configuration of the shape-memory polymer. | 10-16-2014 |
20140302991 | USE OF PHENYLPYRAZOLIN-3-CARBOXYLATES FOR IMPROVING PLANT YIELD - Compounds (A) can be used for increasing the yield of useful plants or crop plants with respect to their harvested plant organs, wherein the Compound (A) is selected from compounds of the formula (I) or salts thereof, | 10-09-2014 |
20140302988 | 1,2,4-Triazolyl-Substituted Ketoenols - The invention relates to novel compounds of the formula (I) | 10-09-2014 |
20140302987 | USE OF SUBSTITUTED ISOQUINOLINONES, ISOQUINOLINDIONES, ISOQUINOLINTRIONES AND DIHYDROISOQUINOLINONES OR IN EACH CASE SALTS THEREOF AS ACTIVE AGENTS AGAINST ABIOTIC STRESS IN PLANTS - Use of substituted isoquinolinones, isoquinolinediones, isoquinolinetriones and dihydroisoquinolinones of the general formula (I) or their respective salts | 10-09-2014 |
20140302426 | METHOD FOR PRODUCING A HOLOGRAPHIC FILM - The invention relates to a method for producing holographic films, in which a photopolymer formulation is provided which comprises as constituents matrix polymers, writing monomers, a photoinitiator system, optionally a non-photopolymerizable component and optionally catalysts, radical stabilizers, solvents, additives and other auxiliaries and/or additives. The photopolymer formulation is applied in a planar manner and in the form of a film on a support film and the photopolymer formulation is dried on the support film at a temperature 60100 DEG C. and are above the temperature T by at least 30 DEG C., and a photopolymer formulation having a plateau module of =0.030 MPa is used. | 10-09-2014 |
20140302425 | METHOD FOR PRODUCING HOLOGRAPHIC MEDIA - The invention relates to a method for producing holographic media, wherein a photopolymer formulation comprising matrix polymers, writing monomers, a photoinitiator system, and optionally auxiliary materials and additives as components is provided, the photopolymer formulation is applied as a coating on the surface of a carrier film and the photopolymer formulation is dried on the carrier film at a temperature XXYY DEG C., wherein only those compounds having TGA 95 values >100 DEG C. and at least 30 DEG C. above the temperature T are selected as components for the photopolymer formulation. The invention further relates to a holographic medium that can be obtained by means of the method according to the invention. | 10-09-2014 |
20140302010 | SUBSTITUTED BENZIMIDAZOLES - The present invention relates to substituted benzimidazole compounds of general formula (I) in which R | 10-09-2014 |
20140300015 | METHOD FOR PRODUCING BALLAST BODIES - The invention relates to a method for producing load transferring regions in a ballast body of a track superstructure by introducing curable liquid plastics or reactive plastic mixtures from a mixing unit by means of at least two distributor pipes with outlets into the load transferring regions and allowing the plastic or the reactive plastic mixture to cure in said load transferring regions. The two distributor pipes with outlets are positioned on the left or on the right from the outside of the rails into the region between the two rails such that the outlets are located adjacent to each other and are laterally spaced from the front face ( | 10-09-2014 |
20140299821 | METHOD FOR PRODUCING A METAL NANOPARTICLE DISPERSION, METAL NANOPARTICLE DISPERSION, AND USE OF SAID METAL NANOPARTICLE DISPERSION - The invention relates to a method for producing a metal nanoparticle dispersion, in particular a silver nanoparticle dispersion, wherein after the production of nanoscale metal particles, stabilized by means of at least one auxiliary dispersing agent containing at least one free carboxylic acid group or salt thereof as a functional group, in at least one liquid dispersant (solvent), flocculation of the metal nanoparticles is deliberately caused, the formed metal nanoparticle flocculation is dispersed again in at least one liquid dispersant, optionally by adding a base, and the metal nanoparticle dispersion is set to a desired metal nanoparticle concentration. The invention further relates to a metal nanoparticle dispersion, in particular a silver nanoparticle dispersion, in particular produced by means of the method according to the invention, and to the use of said metal nanoparticle dispersion. | 10-09-2014 |
20140296304 | Pharmaceutically Active Disubstituted Pyridine Derivatives - The present invention relates to disubstituted pyridine derivatives and/or pharmaceutically acceptable salts thereof, the use of these derivatives as pharmaceutically active agents, especially for the prophylaxis and/or treatment of infectious diseases, including opportunistic diseases, immunological diseases, autoimmune diseases, cardiovascular diseases, cell proliferative diseases, inflammation, erectile dysfunction and stroke, and pharmaceutical compositions containing at least one of said disubstituted pyridine derivatives and/or pharmaceutically acceptable salts thereof. Furthermore, the present invention relates to the use of said disubstituted pyridine derivatives as inhibitors for a protein kinase. | 10-02-2014 |
20140296301 | TOPICAL OPHTHALMOLOGICAL PHARMACEUTICAL COMPOSITION CONTAINING REGORAGENIB - The present invention relates to topical ophthalmological pharmaceutical compositions containing regorafenib, a hydrate, solvate or pharmaceutically acceptable salt thereof or a polymorph thereof and its process of preparation and its use for treating ophthalmological disorders. | 10-02-2014 |
20140296231 | AMINO-SUBSTITUTED IMIDAZOPYRIDAZINES - The present invention relates to amino-substituted imidazopyridazine compounds of general formula (I): in which A, R1, R3 and n are as defined in the claims, to methods of preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyper-proliferative and/or angiogenesis disorder, as a sole agent or in combination with other active ingredients. | 10-02-2014 |
20140295329 | HOLOGRAPHIC MEDIUM HAVING A PROTECTIVE LAYER - This invention relates to a holographic medium comprising a protective layer and a photopolymer film which is bonded to the protective layer and contains polyurethane matrix polymers, acrylate writing monomers and photoinitiators, wherein the protective layer is impermeable to the constituents of the photopolymer film, is optically clear and is transparent to electromagnetic radiation having a wavelength in the range of from 350 to 800 nm. The invention further provides the use of a holographic medium according to the invention in the production of holograms, and a process for the production of a holographic medium according to the invention. | 10-02-2014 |
20140295328 | CHAIN TRANSFER REAGENTS IN POLYURETHANE-BASED PHOTOPOLYMER FORMULATIONS - The present invention relates to photopolymer formulations comprising: matrix polymers (A), obtainable by reacting at least one polyisocyanate component (a) and one isocyanate-reactive component (b); a writing monomer (B); a photoinitiator (C); a catalyst (D); and a chain transfer reagent (E). A holographic medium that contains a photopolymer formulation according to the invention or can be obtained by using it, the use of a photopolymer formulation according to the invention for manufacturing holographic media, and a method for producing a holographic medium by using a photopolymer formulation according to the invention are also subject matter of the invention. | 10-02-2014 |
20140294968 | POLYACRYLATE-BASED ACTIVE COMPOUND-COMPRISING PARTICLES - The invention relates to novel polyacrylate-based active compound-comprising particles which bind to hair, and to the use of these particles for preparing medicaments, in particular for veterinary medicine. The particles comprise uncharged and cationic polyacrylate and are at most 10 um big. | 10-02-2014 |
20140290834 | AUTOMATED MANUFACTURING PROCESSES FOR PRODUCING DEFORMABLE POLYMER DEVICES AND FILMS - A process for producing a patterned deformable polymer film for use in a deformable polymer device is disclosed. The process includes positioning an intermediary layer between a deformable film and a process tooling and printing at least one electrode on the deformable film by depositing an ink to form the at least one electrode on a first surface of the deformable film, wherein the intermediary layer permits release of the deformable film from the process tooling subsequent to the printing process. Films produced by the inventive processes may find use in electroactive polymer devices. | 10-02-2014 |
20140288303 | PROCESS FOR PREPARING METHYL METHYLCARBAMATE AND ITS PURIFICATION FOR USE AS PHARMACEUTICALLY ACTIVE COMPOUND - The present invention relates to a process for preparing methyl {4,6-diamino-2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-yl}methylcarbamate of the formula (I) | 09-25-2014 |
20140288204 | RIGID POLYURETHANE FOAMS WITH UNIFORM CELL SIZE DISTRIBUTION AND HOMOGENEOUS OPEN-CELL CONTENT - The present invention relates to predominantly open-cell, cold-deformable, rigid polyurethane foams which possess a uniform cell structure with similar cell sizes and similar physical properties, more particularly a similar open-cell content. These foams are suitable for producing automotive interior trim, more particularly roof linings and pillar trim. | 09-25-2014 |
20140288118 | N-BIARYLAMIDES - The invention relates to N-biarylamides, methods for production and use thereof for the production of medicaments for the treatment and/or prophylaxis of diseases and for improvement in cognition, concentration power, learning power and/or memory. | 09-25-2014 |
20140288069 | AMINO-SUBSTITUTED IMIDAZOPYRIDAZINES AS MKNK1 KINASE INHIBITORS - The present invention relates to amino imidazopyridazine compounds of general formula (I): in which A, R1, R2, R3 and R4 are as defined in the claims, to methods of preparing said compounds, to pharmaceutical compositions and combinations comprising said 10 compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyper-proliferative and/or angiogenesis disorder, as a sole agent or in combination with other active ingredients. | 09-25-2014 |
20140288035 | 18-METHYL-6,7-METHYLENE-3-OXO-17-PREGN-4-ENE-21,17B-CARBOLACTONES, PHARMACEUTICAL PREPARATIONS COMPRISING SAID COMPOUNDS AND USE THEREOF IN THE TREATMENT OF ENDOMETRIOSIS - The present invention relates to 18-methyl-6,7-methylene-17-pregn-4-ene-21,17β-carbolactones of general formula I | 09-25-2014 |
20140287984 | POLYETHYLENE GLYCOL BASED PRODRUG OF ADRENOMEDULLIN AND USE THEREOF - The invention relates to novel polyethylene glycol (PEG) based prodrug of Adrenomedullin, to processes for preparation thereof, to the use thereof for treatment and/or prevention of diseases, and to the use thereof for producing medicaments for treatment and/or prevention of diseases, especially of cardiovascular, edematous and/or inflammatory disorders. | 09-25-2014 |
20140275525 | METHOD FOR PRODUCING POLYISOCYANATES AND USE THEREOF - The invention relates to a method for modifying isocyanates using catalysts having a water content not exceeding 1,000 ppm. | 09-18-2014 |
20140275475 | SEMIBATCHWISE PROCESS FOR PREPARING OLEFIN-CO COPOLYMERS - A process for preparing olefin-CO copolymers with the steps of:
| 09-18-2014 |
20140275371 | PROCESS FOR PREPARING OLEFIN-CO TERPOLYMERS - The present invention relates to a process for preparing olefin-CO terpolymers with the steps of:
| 09-18-2014 |
20140275199 | SUBSTITUTED 3-(BIPHENYL-3-YL)-4-HYDROXY-8-METHOXY-1-AZASPIRO[4.5]DEC-3-EN-2-ONE - The invention relates to substituted 3-(biphenyl-3-yl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]dec-3-en-2-ones, in particular for therapeutic purposes, to pharmaceutical compositions and to their use in therapy, in particular for the prophylaxis and therapy of neoplastic disorders. | 09-18-2014 |
20140256956 | METHOD FOR PRODUCING DITHINE TETRACARBOXIMIDES - The present invention relates to a new process for preparing dithiine-tetracarboximides. | 09-11-2014 |
20140256908 | PROCESS FOR THE PRODUCTION OF POLYETHER CARBONATE POLYOLS - The present invention relates to a method for producing polyether carbonate polyols from one or more H-functional starter substances, one or more alkylene oxides and carbon dioxide, in the presence of at least one double metal cyanide (DMC) catalyst, wherein the double metal cyanide catalyst comprises a complex-forming component selected from the group consisting of polycarbonate diol, polyether carbonate polyol, polyethylene glycol diol and poly(tetramethylene ether diol). | 09-11-2014 |
20140256902 | HOMOGENEOUS EXTRUDED ARTICLES MADE FROM THERMOPLASTICALLY PROCESSABLE POLYURETHANES BASED ON POLYESTER DIOLS FORMED FROM SUCCINIC ACID AND 1,3-PROPANEDIOL - The present invention relates to homogeneous extruded articles made from thermoplastically processable polyurethanes based on polyester diols formed from succinic acid and 1,3-propanediol. | 09-11-2014 |
20140256728 | COMPOUNDS WITH NEMATICIDAL ACTIVITY - The present invention relates to the use of predominantly known pyridyl carboxamide derivatives as nematicides, compositions containing such compounds and methods for the control of nematodes. | 09-11-2014 |
20140256718 | HYDROXYMETHYLARYL-SUBSTITUTED PYRROLOTRIAZINES AS ALK1 INHIBITORS - This invention relates to novel 5-[(hydroxymethyl)aryl]-substituted pyrrolo[2,1-f][1,2,4]triazin-4-amines of formula (I), to processes for the preparation of such compounds, to pharmaceutical compositions containing such compounds, and to the use of such compounds or compositions for treating angiogenesis-related disorders, in particular angiogenesis-related ocular disorders. | 09-11-2014 |
20140256716 | USE AND AGROCHEMICAL COMPOSITION OF CARBOXYLIC ACID DIBUTYLAMIDES - The invention relates to the use of C | 09-11-2014 |
20140255824 | SULPHUR-CONTAINING CHAIN TRANSFER REAGENTS IN POLYURETHANE-BASED PHOTOPOLYMER FORMULATIONS - The present invention relates to photopolymer formulations comprising: matrix polymers (A), obtainable by reacting at least one polyisocyanate component (a) and one isocyanate-reactive component (b); a writing monomer (B); a photoinitiator (C) a catalyst (D); and a sulphur-containing chain transfer reagent (E). A holographic medium that contains a photopolymer formulation according to the invention or can be obtained by using it, the use of a photopolymer formulation according to the invention for manufacturing holographic media, and a method for producing a holographic medium by using a photopolymer formulation according to the invention are also subject matter of the invention. | 09-11-2014 |
20140255392 | SUBSTITUTED IMIDAZOPYRIDINES AND INTERMEDIATES THEREOF - The present invention relates to substituted imidazopyridine compounds of general formula (I) in which R | 09-11-2014 |
20140255373 | ALPHA-ALKOXYSILANE-TERMINATED PREPOLYMER FOR FAST-CURING SPRAY FOAMS WITH IMPROVED PROPELLANT GAS SOLUBILITY - The present invention relates to an alpha-alkoxysilane-terminated prepolymer preparable by reaction of at least one polyether polyol, of a polyisocyanate and of an alpha-alkoxysilane having at least one isocyanate-reactive group, said polyether polyol having a weight average of 500 to 7000 g/mol and having ethylene oxide and propylene oxide units, the proportion of ethylene oxide units being up to 50% by weight based on the polyether polyol. The invention further provides a process for preparing an inventive alpha-alkoxysilane-terminated prepolymer, a composition, a multicomponent system and a spray can comprising an inventive alpha-alkoxysilane-terminated prepolymer, and also a moulding obtainable by polymerization from an inventive alpha-alkoxysilane-terminated prepolymer. | 09-11-2014 |
20140249289 | METHOD FOR PRODUCING LIGHT-COLOURED POLYISOCYANATES - The invention relates to a method for producing light-coloured polyisocyanates by phosgenation of mixtures comprising MDA and polycyclic aromatic polyamines that have o-phenylenediamine units incorporated via methylene bridges. The invention further relates to the polyisocyanate mixtures obtainable by this method. | 09-04-2014 |
20140249267 | COLD CONTACT ADHESIVES - An aqueous dispersion comprising at least one polyurethane polymer with a melting temperature in the range of 30° C. to 50° C. and (cold contact) adhesives comprising such a polyurethane dispersion, a method for creating an adhesive bonding and the use of such (cold contact) adhesives for creating an adhesive bonding. | 09-04-2014 |
20140249266 | POLYURETHANE UREA DISPERSIONS - The present invention relates to aqueous polyurethane urea dispersions based on polyester polyols, which dispersions result in low emissions and are used as coating compositions. | 09-04-2014 |
20140249149 | Compounds with Nematicidal Activity - The present invention relates to the use of known pyridyl carboxamide derivatives and novel pyridyl carboxamide derivatives as nematicides, compositions containing such compounds and methods for the control of nematodes. | 09-04-2014 |
20140248349 | PROCESS FOR THE PREPARATION OF A SOLID, ORALLY ADMINISTRABLE PHARMACEUTICAL COMPOSITION - The present invention relates to a process for the preparation of a solid, orally administrable pharmaceutical composition, comprising 5-chloro-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl}-methyl)-2-thiophenecarboxamide in hydrophilized form, and its use for the prophylaxis and/or treatment of diseases. | 09-04-2014 |
20140248208 | CATALYST AND METHOD FOR PRODUCING CHLORINE BY MEANS OF A GAS-PHASE OXIDATION - A catalyst material for producing chlorine by the catalytic gas-phase oxidation of hydrogen chloride, wherein the catalyst comprises oxide compounds of cerium as active component components and zirconium dioxide as supporting component and the catalyst h as a particularly high space-time yield with respect to the reactor volume | 09-04-2014 |
20140243561 | PROCESS FOR PREPARING 2,2-DIFLUOROETHANOL - Process for preparing 2,2-difluoroethanol, comprising the following steps: reacting 1-chloro-2,2-difluoroethane with an alkali metal salt of formic acid or acetic acid in a suitable solvent to give the corresponding 2,2-difluoroethyl formate or 2,2-difluoroethyl acetate, and transesterifying the 2,2-difluoroethyl formate or 2,2-difluoroethyl acetate from step (i) in the presence of an alcohol and optionally of a base. | 08-28-2014 |
20140243467 | POLYCARBONATE COMPRISING GLASS FIBRES - The present invention relates to a thermoplastic moulding composition composed of polycarbonate and inorganic fillers which comprises from 0.01 to 0.5 part by weight of at least one anhydride-modified alpha-olefin terpolymer and which has a high degree of rigidity and nevertheless exhibits good strength, as well as stress-strain characteristics corresponding to those of an unreinforced polycarbonate. Surprisingly, the moulding composition additionally exhibits an improvement in flame retardancy. The invention relates in particular to flame-retardant, thermoplastic moulding compositions filled with glass fibres, and to the production and use thereof. The property profile is, surprisingly, independent of the degree of interaction of the filler with the polycarbonate matrix. | 08-28-2014 |
20140243295 | USE OF SUBSTITUTED 2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLINES - The present invention relates to: —use of a 2,3-dihydroimidazo[1,2-c]quinazoline compound, or of a pharmaceutical composition containing same, as a sole active agent, or of a combination of a) said compound or a pharmaceutical composition containing said compound and b) one or more further active agents, for the preparation of a medicament for the treatment or prophylaxis of cancer; —combinations of a) said compound and b) one or more further active agents; —a pharmaceutical composition comprising said compound as a sole active agent for the treatment of breast cancer; —a pharmaceutical composition comprising a combination of a) said compound and b) one or more further active agents; —use of biomarkers involved in the modification of Bel expression, HER family expression and/or activation, PIK3CA signaling and/or loss of PTEN for predicting the sensitivity and/or resistance of a cancer patient to said compound and providing a rationale-based synergistic combination as defined herein to increase sensitivity and/or to overcome resistance; and —a method of determining the level of a component of one or more of Bcl expression, HER family expression and/or activation, PIK3CA signaling and/or loss of PTEN. | 08-28-2014 |
20140235865 | METHOD FOR PRODUCING TETRAZOLE-SUBSTITUTED ANTHRANILIC ACID DIAMIDE DERIVATIVES BY REACTING PYRAZOLIC ACIDS WITH ANTHRANILIC ACID ESTERS - The present invention relates to a process for preparing tetrazole-substituted anthranilic acid diamide derivatives of the formula (1) | 08-21-2014 |
20140235446 | 2,3-DIPHENYL-VALERONITRILE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS - The compounds of the formula (I) | 08-21-2014 |
20140234613 | PROCESS FOR PRODUCING A RIGID POLYURETHANE-ISOCYANURATE FOAM - The invention provides a process for producing rigid polyurethane-polyisocyanurate foams using polyols having a high proportion of secondary hydroxyl end groups. The invention further relates to the rigid polyurethane-polyisocyanurate foams thus obtainable and to the use thereof in the production of composite elements from rigid polyurethane-polyisocyanurate foams and suitable outer layers. The invention further provides the composite elements thus obtainable. | 08-21-2014 |
20140234601 | PROCESS FOR PRODUCING METALLIZED MULTI-LAYER BODIES FROM SPECIAL POLYCARBONATES - The invention relates to a process for producing multi-layer bodies which carry at least one metal layer. The invention further relates to multi-layer products having at least three layers, comprising a substrate layer made of a substrate and containing special copolycarbonates, a metal layer and at least one additional layer. | 08-21-2014 |
20140234284 | FAST-SETTING ALKOXYSILANE SPRAY FOAMS - The present invention relates to an isocyanate-free multi-component system, in particular for medical uses such as foamable wound coverings, with at least two separate components, wherein the first component comprises at least one alkoxysilane-terminated prepolymer and the second component comprises an aqueous component, wherein the aqueous component is a polyurethane dispersion. | 08-21-2014 |
20140234283 | FAST-CURING ALKOXYSILANE SPRAY FOAMS - The present invention relates to an isocyanate-free multicomponent system, especially for production of foams for medical products such as wound dressings, comprising at least two separate components, the first component comprising at least one alkoxysilane-terminated prepolymer and the second component an aqueous component, and the aqueous component having a pH of 4.0 to 9.5 at 20 DEG C. | 08-21-2014 |
20140233243 | USE OF A LIGHT-DIFFUSING POLYCARBONATE SHEET AS A LIGHT COVER - The present invention therefore provides for the use of a light-diffusing polycarbonate sheet based on a composition comprising A) 99.9 to 80% by weight of polycarbonate and B) 0.1 to 20% by weight of diffusing pigment selected from at least one from the group of the silicone resins and the acrylate resins as a light cover, preferably in LED light applications. | 08-21-2014 |
20140232240 | ELECTROACTIVE POLYMER ENERGY CONVERTER - A balanced multi-phase energy conversion apparatus configured to convert energy from a mechanical energy source into electrical energy is disclosed. The energy conversion apparatus may comprise a plurality of transducers. Each of the plurality of transducers comprises a dielectric elastomer module comprising at least one dielectric elastomer film layer disposed between at least first and second electrodes. A transmission coupling mechanism is coupled to the mechanical energy source and operatively attached to the plurality of transducers. The transmission coupling cyclically strains and relaxes the plurality of transducers in response to the mechanical energy acting on the transmission coupling mechanism. The transmission coupling mechanism comprises a work cycle. The plurality of transducers are at evenly distributed points in the work cycle such that a total passive strain energy is constant. | 08-21-2014 |
20140221661 | PROCESS FOR THE PREPARATION OF 4-CARBONYL)AMINO]-3-FLUOROPHENOXY}-N-ETHYLPYRIDINE-2-CARBOXAMIDE, ITS SALTS AND MONOHYDRATE - The present invention relates to a process for preparing 4-(4-[({[4-chloro-3-(trifluoromethyl)-phenyl]amino}carbonyl)amino]-3-fluorophenoxy)-N-methylpyridine-2-carboxamide, its salts and monohydrate. | 08-07-2014 |
20140221602 | METHOD FOR ACTIVATING DOUBLE METAL CYANIDE CATALYSTS FOR THE PRODUCTION OF POLYETHER CARBONATE POLYOLS - The present invention relates to a process for the activation of double metal cyanide (DMC) catalysts with heterocumulenes for the preparation of polyether carbonate polyols by catalytic copolymerization of carbon dioxide (CO | 08-07-2014 |
20140221243 | USE OF CCNE2 AS A STRATIFICATION MARKER IN THE TREATMENT OF BREAST TUMOURS WITH NOVEL PAN-CDK INHIBITORS - The invention relates to the use of CCNE2 as stratification marker in the treatment of breast tumours with novel pan-CDK inhibitors of the formula (I). | 08-07-2014 |
20140220273 | POLYMER COMPOSITION HAVING A FILLER CONTENT AND COEXTRUDED SHEET OBTAINABLE THEREFROM - The present invention relates to a polymer composition containing polycarbonate with a weight-average molecular weight Mw of from 24,000 to 33,000 and 5.0 wt. % to 20.0 wt. % (based on the total amount of the composition) of glass hollow spheres with an alkalinity of less than 1.0 meq/g. The present invention furthermore provides coextruded sheets in which the coextruded layer contains this polymer composition, and shaped articles produced therefrom, in particular containers and pieces of luggage, very particularly suitcases. Sheets which are obtainable with the polymer composition according to the invention have a high mechanical stability, a high scratch resistance, pleasant haptic properties and an excellent homogeneous external visual impression. The present invention furthermore relates to a process for the preparation of these polymer compositions and a process for production of the sheets according to the invention. | 08-07-2014 |
20140215948 | METHOD FOR REINFORCING A BUILDING COMPONENT - A method for reinforcing a part of a building comprises the step of adhesively bonding a textile to the surface of the part of a building by means of an adhesive. The invention relates further to such a reinforced part of a building and to the use of a textile in combination with an adhesive for reinforcing a part of a building, wherein the textile is adhesively bonded to the surface of the part of a building by means of an adhesive. | 08-07-2014 |
20140213813 | Haloalkylmethyleneoxyphenyl-Substituted Ketoenols - The invention relates to novel compounds of the formula (I), | 07-31-2014 |
20140213795 | GERMINAL ALKOXY/ALKYLSPIROCYCLIC SUBSTITUTED TETRAMATE DERIVATIVES - The invention relates to novel compounds of the formula (I) | 07-31-2014 |
20140213679 | EMULSIONS AND THEIR USE IN THE PRODUCTION OF FOAMS BASED ON ISOCYANATES - The invention relates to stable emulsions for the production of foams based on isocyanates, comprising at least three polyols A1a, A1b and A1c and at least one physical blowing agent T, wherein A1a is a polyether polyol, obtained by the addition of epoxies to starter compounds selected from carbohydrates and difunctional or higher-functional alcohols, A1b is a polyether polyol started on an aromatic amine and A1c is a polyester polyether polyol, obtained by the addition of epoxies to the esterification product of an aromatic dicarboxylic acid derivative and a difunctional or higher-functional alcohol. The invention further relates to a method for producing foams by reactions of such emulsions with isocyanates and to the foams obtainable in this way and their use for insulating purposes. | 07-31-2014 |
20140213575 | 6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepines - The invention relates to 6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepines, in particular for therapeutic purposes, pharmaceutical agents and use thereof in therapy, in particular for the prevention and treatment of tumour diseases. | 07-31-2014 |
20140209171 | SOLAR MODULE AND PROCESS FOR PRODUCTION THEREOF - The present invention relates to a solar module comprising a first layer, a solar cell arranged above the first layer and a second layer arranged above the solar cell. The first and/or the second layer comprise a fibre composite material which comprises a preferably aliphatic polyurethane polymer “dual cure” system) crosslinked thermally and by means of electromagnetic radiation. The material of the fibres of the fibre composite material is transparent at least in the region of visible light. The invention further relates to the use of this type of solar module and to a process for production thereof. | 07-31-2014 |
20140206879 | DIPEPTOID PRODRUGS AND THEIR USE - The present application relates to prodrug derivatives of 2-amino-6-({[2-(4-chlorophenyl)-1,3-thiazol-4-yl]methyl}thio)-4-[4-(2-hydroxyethoxy)phenyl]pyridine-3,5-dicarbonitrile, processes for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, especially of cardiovascular disorders. | 07-24-2014 |
20140205533 | PROCESS FOR THE PRODUCTION OF CHLORINE USING A CERIUM OXIDE CATALYST IN AN ADIABATIC REACTION CASCADE - A process for the production of chlorine by thermo-catalytic gas phase oxidation of hydrogen chloride and oxygen is described, the process comprising at least (1) a cerium oxide catalyst and (2) an adiabatic reaction cascade, containing at least two adiabatic stages connected in series with intermediate cooling, wherein the molar O | 07-24-2014 |
20140200233 | USE OF MAD2L2 AS A STRATIFICATION MARKER IN THE TREATMENT OF BREAST TUMOURS WITH NOVEL PAN-CDK INHIBITORS - The invention relates to the use of MAD2L2 as stratification marker in the treatment of breast tumours with novel pan-CDK inhibitors of the formula (I). | 07-17-2014 |
20140194623 | PROCESS FOR PREPARING TETRAZOLE-SUBSTITUTED ANTHRANILIC ACID DIAMIDE DERIVATIVES BY REACTING BENZOXAZINONES WITH AMINES - The present invention relates to a process for preparing tetrazole-substituted anthranilic acid diamide derivatives of the formula (I) | 07-10-2014 |
20140194430 | SUBSTITUTED AMINOIMIDAZOPYRIDAZINES - The present invention relates to substituted aminoimidazopyridazine compounds of general formula (I): in which A, R1, R2, R3 and R4 are as defined in the claims, to methods of preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyper-proliferative and/or angiogenesis disorder, as a sole agent or in combination with other active ingredients. | 07-10-2014 |
20140194318 | BIOMARKERS FOR DIAGNOSING ALZHEIMER'S DISEASE - A method for assessing the state of Alzheimer's disease in patients is disclosed. A method for monitoring the progression of Alzheimer's disease in patients is also disclosed. The method applies detection of specific peptide markers, e.g., using mass spectrometric analysis. | 07-10-2014 |
20140190369 | POLYURETHANE POLYMERS - The present invention relates to polyurethane polymers, a process for their preparation and their use as binders for adhesives, coatings or foams. | 07-10-2014 |
20140187705 | ADHESIVES - The present invention relates to adhesives based on silane-modified polymers and to substrates coated therewith and connected thereto. | 07-03-2014 |
20140187548 | 6 SUBSTITUTED IMIDAZOPYRAZINES FOR USE AS MPS-1 AND TKK INHIBITORS IN THE TREATMENT OF HYPERPROLIFERATIVE DISORDERS - The present invention relates to substituted imidazopyrazine compounds of general formula (I) in which R | 07-03-2014 |
20140187491 | RELAXIN FUSION POLYPEPTIDES AND USES THEREOF - The present invention provides Relaxin fusion polypeptides A-L-B with a non-wild type array of the Relaxin A-chain and Relaxin B-chain, wherein the A- and B-chains are connected by a linker peptide. The invention further provides Relaxin fusion polypeptides with extended half-life. Furthermore, the invention provides nucleic acid sequences encoding the foregoing fusion polypeptides, vectors containing the same, pharmaceutical compositions and medical use of such fusion polypeptides. | 07-03-2014 |
20140187420 | ACTIVE COMPOUND COMBINATIONS - The present invention relates to active compound combinations, in particular within a fungicide composition, which comprises (A) Prothioconazole and (B) Iprodione. Moreover, the invention relates to a method for curatively or preventively controlling the phytopathogenic fungi of plants or crops, to the use of a combination according to the invention for the treatment of seed, to a method for protecting a seed and not at least to the treated seed. | 07-03-2014 |
20140186444 | DRUG FORMULATIONS HAVING IMPROVED PHARMACOKINETIC PROPERTIES - The present application relates to novel drug formulations of vardenafil which dissolve rapidly in the mouth and lead to increased bioavailability and to a plateau-like plasma concentration profile, and to processes for their preparation. | 07-03-2014 |
20140179662 | PHARMACEUTICALLY ACTIVE DISUBSTITUTED TRIAZINE DERIVATIVES - The present invention relates to disubstituted triazine derivatives and/or pharmaceutically acceptable salts thereof, the use of these derivatives as pharmaceutically active agents, especially for the prophylaxis and/or treatment of infectious diseases, including opportunistic diseases, immunological diseases, autoimmune diseases, cardiovascular diseases, cell proliferative diseases, inflammation, erectile dysfunction and stroke, and pharmaceutical compositions containing at least one of said disubstituted triazine derivatives and/or pharmaceutically acceptable salts thereof. Furthermore, the present invention relates to the use of said disubstituted triazine derivatives as inhibitors for a protein kinase. | 06-26-2014 |
20140179623 | ECTOPARASITICIDAL ACTIVE SUBSTANCE COMBINATIONS - The present application relates to active compound combinations of pyrazin-2-ylpyrazoles (component A) with at least one further ectoparasiticide or synergists (component B), and to products comprising such active compound combinations. These active compound combinations are suitable for controlling animal pests in the field of veterinary medicine. | 06-26-2014 |
20140179527 | N-(TETRAZOL-5-YL)- AND N-(TRIAZOL-5-YL)ARYLCARBOXAMIDES AND USE THEREOF AS HERBICIDES - N-(Tetrazol-5-yl)- and N-(triazol-5-yl)arylcarboxamides of the general formula (I) are described as herbicides. | 06-26-2014 |
20140171474 | FUNGICIDE N-CYCLOALKYL-N-BIPHENYLMETHYL-CARBOXAMIDE DERIVATIVES - The present invention relates to N-cycloalkyl-N-biphenylmethyl-carboxamide derivatives of formula (I) | 06-19-2014 |
20140171434 | SUBSTITUTED IMIDAZOPYRIDINES AND IMIDAZOPYRIDAZINES AND THE USE THEREOF - The present application relates to novel substituted imidazopyridines and imidazopyridazines, to processes for their preparation, to their use, alone or in combinations, for the treatment and/or prophylaxis of diseases and to their use for the production of medicaments for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of cardiovascular disorders. | 06-19-2014 |
20140162981 | SUBSTITUTED ARYLOXAZOLES AND THEIR USE - The present application relates to novel substituted aryloxazole derivatives, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, preferably for the treatment and/or prevention of cardiovascular and metabolic disorders. | 06-12-2014 |
20140162006 | WATER-BLOWN PUR/PIR RIGID FOAM MATERIAL THAT CAN BE SPRAYED - The invention relates to a method for producing a water-blown polyurethane/polyisocyanurate rigid foam material that can be sprayed, by reacting a mixture comprising an aromatic polyester polyol, a first, comparatively short-chain aliphatic polyether polyol, a second, comparatively long-chain aliphatic polyether polyol, an isocyanate component, a blowing agent having water at least as a main component, and a catalyst component. The invention further relates to a rigid foam produced according to the method according to the invention, a composite material composed of said rigid foam and a pipe, and to the use of such a composite material for transporting liquid or gaseous media. | 06-12-2014 |
20140161526 | PROCESS FOR THE PRODUCTION OF BALLAST - A process for the production of ballast for railway track laying, road construction, dam construction and bank protection, wherein ballast stones are spread out to form ballast and a reaction mixture for the preparation of a polyurethane foam, produced from components by a low-pressure process, is applied between the spread ballast stones. | 06-12-2014 |
20140155637 | CHIRAL SYNTHESIS OF N--1-[2,3-DIHYDROXY-PROPYL]CYCLOPROPANESULFONAMIDES - The present invention relates to a novel enantioselective method of preparing (S)- and (R)-enantiomers of N-{3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]-6-5 methoxyphenyl}-1-[2,3-dihydroxy-propyl]cyclopropanesulfonamide, to novel intermediate compounds, and to the use of said novel intermediate compounds for the preparation of said (S)- and (R)-enantiomers of N-{3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]-6-methoxyphenyl}-1-[2,3-dihydroxy-propyl]cyclopropanesulfonamide. | 06-05-2014 |
20140155401 | NOVEL SUBSTITUTED BIPYRIDINE DERIVATIVES AND THEIR USE AS ADENOSINE RECEPTOR LIGANDS - The present invention relates to novel substituted 2,4′- and 3,4′-bipyridine derivatives, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, preferably for the treatment and/or prevention of hypertension and other cardiovascular disorders. | 06-05-2014 |
20140155383 | USE OF CATHEPSIN K INHIBITION FOR THE TREATMENT AND/OR PROPHYLAXIS OF PULMONARY HYPERTENSION AND/OR HEART FAILURE - The present invention relates to the use of cathepsin K and/or cathepsin S inhibitors in a method for the treatment and/or prophylaxis of pulmonary hypertension and/or heart failure. | 06-05-2014 |
20140148611 | METHOD FOR THE PRODUCTION OF 2-AMINO-5-CYANO-N,3-DIMETHYLBENZAMIDE - The present invention relates to a process for preparing 2-amino-5-cyano-N,3-dimethylbenzamide of formula (1) | 05-29-2014 |
20140148604 | PROCESS FOR PREPARING SODIUM SALTS OR POTASSIUM SALTS OF 4-HYDROXY-2-OXO-2,5-DIHYDROFURAN-3-CARBOXYLATE - Process for preparing sodium or potassium salts of 4-hydroxy-2-oxo-2,5-dihydrofuran-3-carboxylic esters, comprising the reaction of a malonic ester with potassium hydroxide to give the corresponding malonic ester potassium salt of the formula (III) | 05-29-2014 |
20140148433 | BICYCLIC AZA HETEROCYCLES, AND USE THEREOF - The present application relates to novel bicyclic azaheterocycles, to processes for preparation thereof, to the use thereof, alone or in combinations, for treatment and/or prophylaxis of diseases and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially for treatment and/or prophylaxis of cardiovascular disorders. | 05-29-2014 |
20140148390 | FUSION PROTEINS RELEASING RELAXIN AND USES THEREOF - The present invention provides Relaxin fusion proteins, wherein a linker connects the carboxy-terminus of Relaxin with a proteinaceous half-life extending moiety and the linker comprises a protease cleavage site. Therefore, the invention provides Relaxin fusion polypeptides with extended half-life whereby the fusion protein by itself serves as a depot for release of the biologically active Relaxin. Furthermore, the invention provides nucleic acid sequences encoding the foregoing fusion polypeptides, vectors containing the same, cells expressing the Relaxin fusion polypeptides, pharmaceutical compositions and medical use of such fusion polypeptides. | 05-29-2014 |
20140148338 | ACTIVE COMPOUND COMBINATIONS - The present invention relates to active compound combinations, in particular within a fungicide composition, which comprises (A) a thiazolylisoxazoline of formula (I) and a further fungicidally active compound (B). Moreover, the invention relates to a method for curatively or preventively controlling the phytopathogenic fungi of plants or crops, to the use of a combination according to the invention for the treatment of seed, to a method for protecting a seed and not at least to the treated seed. | 05-29-2014 |
20140142244 | AQUEOUS RESIN COMPOSITION COMPRISING A POLYESTER-POLYURETHANE RESIN INCLUDING A DENDRITIC POLYOL - An aqueous resin composition comprises a polyester-polyurethane resin which is obtained by reacting, in a one-stage process or multi-stage process, a reaction mixture comprising a polyester polyol with a number-average molecular weight M | 05-22-2014 |
20140142069 | SUBSTITUTED 3-PHENYLPROPIONIC ACIDS AND THE USE THEREOF - The present application relates to novel 3-phenylpropionic acid derivatives, to processes for their preparation, to their use for the treatment and/or prevention of diseases and to their use for preparing medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of cardiovascular disorders. | 05-22-2014 |
20140141003 | NEUTRALIZING PROLACTIN RECEPTOR ANTIBODY MAT3 AND ITS THERAPEUTIC USE - The neutralizing prolactin receptor antibody Mat3, and antigen binding fragments, pharmaceutical compositions containing them and their use in the treatment or prevention of benign disorders and indications mediated by the prolactin receptor such as endometriosis, adenomyosis, non-hormonal female contraception, benign breast disease and mastalgia, lactation inhibition, benign prostate hyperplasia, fibroids, hyper- and normoprolactinemic hair loss, and cotreatment in combined hormone therapy to inhibit mammary epithelial cell proliferation and for the treatment and prevention of antiestrogen-resistant breast cancer. The antibody blocks prolactin receptor-mediated signalling. | 05-22-2014 |
20140135323 | OXO-SUBSTITUTED IMIDAZO[1,2B]PYRIDAZINES, THEIR PREPARATION AND USE AS PHARMACEUTICALS - The invention relates to novel inhibitors of kinases of the general formula (I): | 05-15-2014 |
20140135319 | 6-SUBSTITUTED IMIDAZOPYRAZINES FOR USE AS MPS-1 AND TKK INHIBITORS IN THE TREATMENT OF HYPERPROLIFERATIVE DISORDERS - The present invention relates to substituted imidazopyrazine compounds of general formula (I): in which R | 05-15-2014 |
20140135219 | USE OF ALS INHIBITOR HERBICIDES FOR CONTROL OF UNWANTED VEGETATION IN ALS INHIBITOR HERBICIDE TOLERANT BRASSICA, SUCH AS B. NAPUS, PLANTS - The present invention relates to the use of the ALS inhibitor herbicides for controlling unwanted vegetation in ALS inhibitor herbicide tolerant | 05-15-2014 |
20140131275 | PROCESS FOR PHASE SEPARATION OR EXTRACTION AND DEVICE SUITABLE THEREFOR - The present invention relates to a device for separating two immiscible phases and/or for extracting one phase with another phase (phase separation or extraction device), comprising at least one vessel for receiving the at least two phases, at least one pipe for supplying a fluid to the vessel, at least one pipe for discharging a fluid from the vessel, and at least one arrangement comprising a transparent disk for observing the separation operation or the extraction operation, wherein at least the side of the transparent disk that faces the phases to be separated or extracted consists of sapphire (sapphire glass) or mica ( mica disk), and to the use of such a device in the preparation of di- and polyamines of the diphenylmethane series. | 05-15-2014 |
20140128638 | PROCESS FOR PREPARING AROMATIC AMINES - The invention relates to a process for the continuous preparation of aromatic amines by hydrogenation of the corresponding nitroaromatics in the presence of catalysts arranged in reaction spaces, in which an adiabatically operated reaction space RA is connected downstream of an isothermally operated reaction space RI and RA additionally also has a separate feed for the nitroaromatic to be hydrogenated, RI is fed with the nitroaromatic to be hydrogenated from the start to the end of the hydrogenation, and the product mixture emerging from RI is fed into RA from the start to the end of the hydrogenation, wherein RA can additionally be fed via the separate feed with the nitroaromatic to be hydrogenated. | 05-08-2014 |
20140128614 | PESTICIDAL DIARYL - HETEROCYCLYL DERIVATIVES - To provide pesticidal allylAryl heterocycle derivatives that are useful as a pesticidal compound. | 05-08-2014 |
20140127240 | Novel Binder-Drug Conjugates (ADCs) and Use of Same - The present patent application relates to novel binder-drug conjugates (ADCs) of N,N-dialkylauristatins directed against the target epidermal growth factor receptor (EGFR, gene ID 1956), effective metabolites of these ADCs, methods for producing these ADCs, use of these ADCs for treatment and or prevention of diseases as well as the use of these ADCs to produce pharmaceutical drugs for treatment and/or prevention of diseases, in particular hyperproliferative and/or angiogenic diseases such as cancer, for example. Such treatments may be administered as monotherapy or in combination with other pharmaceutical drugs or other therapeutic measures. | 05-08-2014 |
20140121285 | Low-Foam Preparations for Crop Protection - Alkyl ether sulfates having 1 to 9 carbon atoms in the alkyl chain and 1 to 20 alkyleneoxy units in the ether moiety are suitable for use as low-foam additives for enhancing the activity of water-soluble or partially water-soluble agrochemicals. They can be used to produce low-foam preparations for crop protection. | 05-01-2014 |
20140121107 | HERBICIDAL COMPOSITIONS FOR TOLERANT OR RESISTANT RICE CROPS - Herbicide combinations with an effective content of:
| 05-01-2014 |
20140121104 | HERBICIDE SAFENER COMPOSITIONS - Herbicide-safener compositions are described, comprising active ingredients from the group of the N-(1,2,5-oxadiazol-3-yl)benzamides and safeners. These herbicidal compositions are particularly suitable for use against harmful plants in crops of useful plants. | 05-01-2014 |
20140121101 | TERNARY FUNGICIDAL COMPOSITIONS COMPRISING A DITHIINO-TETRACARBOXAMIDE FUNGICIDE - The present invention relates to active compound combinations, in particular within a fungicide composition, which comprises (A) a dithiino-tetracarboximide of formula (I), (B) an inhibitor of the ergosterol biosynthesis, in particular an azole compound, and (C) an inhibitor of the respiratory chain at complex III, in particular a strobilurin compound. Moreover, the invention relates to a method for curatively or preventively controlling the phytopathogenic fungi of plants or crops, to the use of a combination according to the invention for the treatment of seed, to a method for protecting a seed and not at least to the treated seed. | 05-01-2014 |
20140120354 | POLYURETHANE POLYMERS - The present invention relates to polyurethane polymers, a process for their preparation and their use as binders for adhesives, coatings or foams. | 05-01-2014 |
20140120087 | TRIAZOLOPYRIDINES - The present invention relates to triazolopyridine compounds of general formula (I): in which R | 05-01-2014 |
20140113901 | IMIDAZOPYRIDAZINES AS AKT KINASE INHIBITORS - Imidazopyridazines of formula (I) a process for their production and the use thereof. | 04-24-2014 |
20140113900 | SUBSTITUTED IMIDAZOPYRIDINES AND THE USE THEREOF - The present application relates to novel substituted imidazopyridazines, to processes for their preparation, to their use, alone or in combinations, for the treatment and/or prophylaxis of diseases and to their use for production of medicaments for the treatment and/or prophylaxis of diseases, especially for the treatment and/or prophylaxis of cardiovascular disorders. | 04-24-2014 |
20140113896 | ARYLAMINOALCOHOL-SUBSTITUTED 2,3-DIHYDROIMIDAZO[1,2-C]QUINOLINES - The present invention relates to substituted phenoxypyridine compounds of general formula (I); in which R | 04-24-2014 |
20140110622 | POLYMER MATERIAL CONTAINING ORGANICALLY MODIFIED LAYERED SILICATES - The present invention relates to a polymer material comprising a polymer and an organically modified layered silicate dispersed in the polymer. The total content of alkali and/or alkaline earth metal cations in the polymer material is ≦1 ppm. It relates further to the use of the polymer material as an electret material, and to an electromechanical converter comprising such a polymer material. | 04-24-2014 |
20140109916 | Transdermal Delivery of Hormones without the Need of Penetration Enhancers - The present invention relates to a patch comprising a drug-containing layer with low content of hormones, such as gestodene, and optionally an estrogen (e.g. ethinyl estradiol). Upon administering the patch to a woman, plasma levels of at least 1.0 ng/ml of Gestodene is achieved at steady state conditions without the need of incorporating penetration enhancers or permeation enhancers in the drug-containing layer. Satisfactorily plasma levels of the hormones is also achieved throughout a period of at least 1 week, making the patch applicable for being used in female contraception with the concept of administering the patch ones weekly. | 04-24-2014 |
20140107367 | METHOD FOR PRODUCING 2-CHLOROALLYL THIOCYANATE AND 2-CHLOROALLYL ISOTHIOCYANATE - A process is described for producing 2-chloroallyl isothiocyanate from 2,3-dichloro-1-propene by reacting the 2,3-dichloro-1-propene with a thiocyanate in the presence of a phase transfer catalyst, without diluent or in the presence of up to 15 percent by weight based on 2,3-dichloropropene and simultaneously in the presence of an excess of from 10 to 200 mol percent of 2,3-dichloro-1-propene based on the thiocyanate. A process starting from 1,2,3-trichloropropane is also described. | 04-17-2014 |
20140107325 | PREPARATION OF HIGH-PURITY GADOBUTROL - What is described is a process for producing high-purity gadobutrol in a purity (according to HPLC) of more than 99.7 or 99.8 or 99.9% and the use for preparing a pharmaceutical formulation for parenteral administration. The process is carried out using specifically controlled crystallization conditions. The more recent developments in the field of the gadolinium-containing MR contrast agents (EP 0448191 B1, CA Patent 1341176, EP 0643705 B1, EP 0986548 B1, EP 0596586 B1) include the MRT contrast agent gadobutrol (Gadovist® 1.0) which has been approved for a relatively long time in Europe and more recently also in the USA under the name Gadavist®. | 04-17-2014 |
20140107291 | MOULDED PARTS CONSISTING OF REINFORCED POLYURETHANE UREA ELASTOMERS AND USE THEREOF - The invention relates to moulded parts provided with reinforcing materials and consisting of polyurethane urea elastomers having defined urea and urethane contents, and to the use thereof. | 04-17-2014 |
20140107245 | PROCESS FOR THE PREPARATION OF POLYETHER POLYOLS - The invention relates to a method for producing polyether carbonate polyols, wherein (i) in a first step a polyether carbonate polyol is produced from one or more H-functional starter substances, one or more alkylene oxides, and carbon dioxide in the presence of at least one DMC catalyst, and (ii) in a second step the polyether carbonate polyol is chain-extended with a mixture of at least two different alkylene oxides in the presence of at least one DMC catalyst. The invention further relates to polyether carbonate polyols that contain a terminal mixed block of at least two alkylene oxides and to a method for producing soft polyurethane foams, wherein a polyol component containing a polyether carbonate polyol according to the invention is used. | 04-17-2014 |
20140107243 | HYDROPHILIC POLYURETHANE FOAM WITH LOW VOLUME SWELLING - The invention relates to a specific composition comprising A) isocyanate-functional prepolymers obtainable by reaction of A1) aliphatic diisocyanates with A2) di- to hexa-functional polyalkylene oxides having an ethylene oxide content of 50 to 100 mol %, based on the total amount of the oxyalkylene groups present, B) an aqueous polyurethane suspension, an aqueous polyacrylate suspension or aqueous silica sols, especially for production of hydrophilic, aliphatic polyurethane foams. The invention further provides a process for producing a hydrophilic, aliphatic polyurethane foam, based on the inventive composition, a polyurethane foam obtainable by the process and a wound dressing comprising the polyurethane foam. | 04-17-2014 |
20140107112 | Agents for Combating Plant Pests - The present invention relates to compositions for controlling plant pests, which contain the compound of the formula (I) | 04-17-2014 |
20140106969 | N-(1,2,5-OXADIAZOL-3-YL)-, N-(TETRAZOL-5-YL)- AND N-(TRIAZOL-5-YL)BICYCLOARYLCARBOXAMIDES AND THEIR USE AS HERBICIDES - N-(1,2,5-Oxadiazol-3-yl)-, N-(tetrazol-5-yl)- and N-(triazol-5-yl)bicycloarylcarboxamides of the general formula (I) are described as herbicides. | 04-17-2014 |
20140105846 | COSMETIC POLYURETHANEUREA COPOLYMER COMPOSITION - The present invention relates to a cosmetic polyurethaneurea copolymer composition comprising a solvent, a polyurethaneurea and a copolymer, said polyurethaneurea being obtainable by reacting a single polyisocyanate component containing at least 75 mol % of IPDI, at least one polymeric polyol component, at least one hydrophilizing component and a single diamine component containing at least 75 mol % of IPDA, and said copolymer being obtainable by reaction of at least one monomer including acrylate groups with at least one further monomer. The invention further provides for the use of the cosmetic composition in cosmetics and a method for shaping hairstyles using the cosmetic composition. | 04-17-2014 |
20140100243 | SUBSTITUTED 4-ARYL-1,4-DIHYDRO-1,6-NAPHTHYRIDINE AMIDES AND THEIR USE - The present application relates to novel substituted 4-aryl-1,4-dihydro-1,6-naphthyridine-3-carboxamides, a process for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, especially cardiovascular disorders. | 04-10-2014 |
20140100229 | FLUOROALKYL-SUBSTITUTED PYRAZOLOPYRIDINES AND USE THEREOF - The present application relates to novel fluoroalkyl-substituted pyrazolopyridines, to processes for their preparation, to their use, alone or in combinations, for the treatment and/or prophylaxis of diseases and to their use for production of medicaments for the treatment and/or prophylaxis of diseases, especially for the treatment and/or prophylaxis of cardiovascular disorders. | 04-10-2014 |
20140100108 | HERBICIDALLY AND FUNGICIDALLY ACTIVE 3-PHENYLISOXAZOLINE-5-CARBOXAMIDES AND 3-PHENYLISOXAZOLINE-5-THIOAMIDES - 3-Phenylisoxazoline-5-carboxamides and 3-phenylisoxazoline-5-thioamides of the formula (I) and their use as herbicides and fungicides are described. | 04-10-2014 |
20140100107 | TERNARY FUNGICIDAL COMPOSITIONS COMPRISING A DITHIINO-TETRACARBOXAMIDE FUNGICIDE - The present invention relates to active compound combinations, in particular within a fungicide composition, which comprises (A) a dithiino-tetracarboximide of formula (I), (B) an inhibitor of the respiratory chain at complex I or II and (C1) an inhibitor of the ergosterol biosynthesis, in particular an azole compound, or (C2) an inhibitor of the respiratory chain at complex III, in particular a strobilurin compound. Moreover, the invention relates to a method for curatively or preventively controlling the phytopathogenic fungi of plants or crops, to the use of a combination according to the invention for the treatment of seed, to a method for protecting a seed and not at least to the treated seed. | 04-10-2014 |
20140094363 | Active Substance for Increasing Pathogenic Defense in Plants and Methods for the Defection Thereof - The invention relates to a method for finding compounds which induce plant pathogen defense, the enhanced expression of individual, or a plurality of, endogenous plant genes from the group consisting of jasmonic acid biosynthesis, plant proteinase inhibitors, plant xylanase inhibitors, plant PR proteins (pathogen-related proteins) and plant chitinases being regarded as a sign that induction has taken place, and to the use of these compounds alone or in combination with known compounds which act specifically and directly against phytopathogens, it being possible to carry out the application either simultaneously or staggered. | 04-03-2014 |
20140093721 | HIGH-TEMPERATURE-RESISTANT FOAMS HAVING LOW THERMAL CONDUCTIVITY - The invention relates to high-temperature-resistant foams having low thermal conductivity, to the production thereof from organic polyisocyanates and polyepoxides, and to the use of the foams. | 04-03-2014 |
20140090094 | MODULATORS OF SLC22A7 - The present invention is directed to the identification of modulators for SLC22A7 transporter and therapeutic uses thereof. Hence, in one embodiment the present invention relates to a method for identifying and/or obtaining a compound capable of modulating glutamate transport, comprising contacting a test compound with a system for measuring those transport activity, which system comprises an SLC22A7 polypeptide or a functional fragment thereof, and a substrate for measuring glutamate transport by the system; and detecting an altered level of the those transport activity of the SLC22A7 polypeptide or functional fragment in the presence of the test compound compared to the described transport activity in the absence of the test compound and/or presence of a control. | 03-27-2014 |