| ABBOTT CARDIOVASCULAR SYSTEMS INC. Patent applications |
| Patent application number | Title | Published |
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| 20160128856 | METHODS AND SYSTEMS FOR DELIVERING AN IMPLANT USING A PLANETARY GEAR ACTUATION ASSEMBLY - A system for delivering an implant including a handle, a trigger, and an actuation assembly. The actuation assembly can include a planet carrier, at least one planet gear operatively coupled to the planet carrier, a sun gear shaft operatively engaged with the planet gear, a ring gear operatively engaged with the planet gear, a first clutch driver, and a second clutch driver. The actuation assembly can be configured to displace the outer tubular member in the proximal direction a distance (d) relative to the handle and to separately move the inner shaft member distally a distance (x) relative to the handle upon deployment of the trigger from a first position to a second position, and move the inner shaft member proximally a distance (y) relative to the handle with no displacement of the outer tubular member upon return of the trigger from the second position to the first position. | 05-12-2016 |
| 20160123443 | METHODS AND SYSTEMS FOR DELIVERING AN IMPLANT USING A PLANETARY GEAR ACTUATION ASSEMBLY - A system for delivering an implant including a handle, a trigger, and an actuation assembly. The actuation assembly can include a planet carrier, at least one planet gear operatively coupled to the planet carrier, a sun gear shaft operatively engaged with the planet gear, a ring gear operatively engaged with the planet gear, a first clutch driver, and a second clutch driver. The actuation assembly can be configured to displace the outer tubular member in the proximal direction a distance (d) relative to the handle and to separately move the inner shaft member distally a distance (x) relative to the handle upon deployment of the trigger from a first position to a second position, and move the inner shaft member proximally a distance (y) relative to the handle with no displacement of the outer tubular member upon return of the trigger from the second position to the first position. | 05-05-2016 |
| 20160123442 | METHODS AND SYSTEMS FOR DELIVERING AN IMPLANT USING A PLANETARY GEAR ACTUATION ASSEMBLY - A system for delivering an implant including a handle, a trigger, and an actuation assembly. The actuation assembly can include a planet carrier, at least one planet gear operatively coupled to the planet carrier, a sun gear shaft operatively engaged with the planet gear, a ring gear operatively engaged with the planet gear, a first clutch driver, and a second clutch driver. The actuation assembly can be configured to displace the outer tubular member in the proximal direction a distance (d) relative to the handle and to separately move the inner shaft member distally a distance (x) relative to the handle upon deployment of the trigger from a first position to a second position, and move the inner shaft member proximally a distance (y) relative to the handle with no displacement of the outer tubular member upon return of the trigger from the second position to the first position. | 05-05-2016 |
| 20160123441 | METHODS AND SYSTEMS FOR DELIVERING AN IMPLANT USING A PLANETARY GEAR ACTUATION ASSEMBLY - A system for delivering an implant including a handle, a trigger, and an actuation assembly. The actuation assembly can include a planet carrier, at least one planet gear operatively coupled to the planet carrier, a sun gear shaft operatively engaged with the planet gear, a ring gear operatively engaged with the planet gear, a first clutch driver, and a second clutch driver. The actuation assembly can be configured to displace the outer tubular member in the proximal direction a distance (d) relative to the handle and to separately move the inner shaft member distally a distance (x) relative to the handle upon deployment of the trigger from a first position to a second position, and move the inner shaft member proximally a distance (y) relative to the handle with no displacement of the outer tubular member upon return of the trigger from the second position to the first position. | 05-05-2016 |
| 20160123440 | METHODS AND SYSTEMS FOR DELIVERING AN IMPLANT USING A PLANETARY GEAR ACTUATION ASSEMBLY - A system for delivering an implant including a handle, a trigger, and an actuation assembly. The actuation assembly can include a planet carrier, at least one planet gear operatively coupled to the planet carrier, a sun gear shaft operatively engaged with the planet gear, a ring gear operatively engaged with the planet gear, a first clutch driver, and a second clutch driver. The actuation assembly can be configured to displace the outer tubular member in the proximal direction a distance (d) relative to the handle and to separately move the inner shaft member distally a distance (x) relative to the handle upon deployment of the trigger from a first position to a second position, and move the inner shaft member proximally a distance (y) relative to the handle with no displacement of the outer tubular member upon return of the trigger from the second position to the first position. | 05-05-2016 |
| 20160120680 | METHODS AND SYSTEMS FOR DELIVERING AN IMPLANT - A system for delivering an implant including a handle, a trigger, and an actuation assembly. The actuation assembly can be configured to displace the outer tubular member in the proximal direction a distance (d) relative to the handle and to separately move the inner shaft member distally a distance (x) relative to the handle upon deployment of the trigger from a first position to a second position, and move the inner shaft member proximally a distance (y) relative to the handle with no displacement of the outer tubular member upon return of the trigger from the second position to the first position. | 05-05-2016 |
| 20160120679 | METHODS AND SYSTEMS FOR DELIVERING AN IMPLANT - A system for delivering an implant including a handle, a trigger, and an actuation assembly. The actuation assembly can be configured to displace the outer tubular member in the proximal direction a distance (d) relative to the handle and to separately move the inner shaft member distally a distance (x) relative to the handle upon deployment of the trigger from a first position to a second position, and move the inner shaft member proximally a distance (y) relative to the handle with no displacement of the outer tubular member upon return of the trigger from the second position to the first position. | 05-05-2016 |
| 20160120678 | METHODS AND SYSTEMS FOR DELIVERING AN IMPLANT - A system for delivering an implant including a handle, a trigger, and an actuation assembly. The actuation assembly can be configured to displace the outer tubular member in the proximal direction a distance (d) relative to the handle and to separately move the inner shaft member distally a distance (x) relative to the handle upon deployment of the trigger from a first position to a second position, and move the inner shaft member proximally a distance (y) relative to the handle with no displacement of the outer tubular member upon return of the trigger from the second position to the first position. | 05-05-2016 |
| 20160120669 | OPTIMAL RATIO OF POLAR AND BENDING MOMENT OF INERTIA FOR STENT STRUT DESIGN - An intravascular stent is provided to be implanted in coronary arteries and other body lumens. The transverse cross-section of at least some of the stent struts have a ratio of polar and bending moments of inertia, which results in optimal resistance to stent twisting. This resistance to twisting ratio for the stent struts minimizes out of plane twisting of the struts or projecting edges of the struts when the stent is expanded from a compressed diameter to an expanded diameter in a coronary artery. | 05-05-2016 |
| 20160120415 | SYSTEM AND METHOD FOR FFR GUIDEWIRE RECOVERY - A kit for coronary treatment comprising a pressure sensing guidewire that includes a pressure sensor for measuring pressure within a patient's vasculature. A sheath comprising a tube having a proximal end and a distal end and defining an internal lumen sized for receiving the pressure sensing guidewire; a hemostasis valve positioned over the proximal end of the tube; a cylindrical element attached to the distal end of the tube, the cylindrical element having an internal lumen sized for receiving a conventional guidewire; wherein the pressure sensing guidewire is configured to be slideably insertable into the tube from the proximal end of the tube; and further wherein, the tube is configured to permit the pressure sensing guidewire, including the pressure sensor, to freely slide distally and proximally within the tube at the election of a user. | 05-05-2016 |
| 20160067459 | BALLOON CATHETER - Balloon catheter includes an outer shaft having a hypotube and a monolithic single-layer distal outer member, a balloon in fluid communication with an inflation lumen, and a monolithic inner tubular member having a guidewire lumen defined therethrough. The outer shaft has the inflation lumen defined therethrough. The monolithic single-layer distal outer member is necked to a reduced diameter along an entire length thereof. A proximal end of the monolithic single-layer distal outer member is coupled to the hypotube. A distal section of the hypotube comprises a skive defined by a first angled cut, an axial cut, and a second angled cut. The balloon has a proximal balloon shaft coupled to a distal end of the monolithic single-layer distal outer member. The monolithic inner tubular member extends distally from a proximal port in the monolithic single-layer distal outer member through the balloon to form a tip. | 03-10-2016 |
| 20160067458 | BALLOON CATHETER - Catheter includes an outer shaft member having a proximal section and a distal outer member. The outer shaft has an inflation lumen defined therethrough. A balloon is in fluid communication with the inflation lumen and has a proximal balloon shaft, a proximal cone portion, a working length, a distal cone portion, and a distal balloon shaft. Catheter also includes a monolithic inner tubular member extending from the outer shaft proximal section through the distal outer member and through the balloon to form a tip. The distal balloon shaft has an inner diameter and comprises a distal seal portion coupled to the inner tubular member and a proximal portion free of attachment to the inner tubular member. The length of the proximal portion of the distal balloon shaft is at least about two times the inner diameter of the distal balloon shaft. Methods of making a catheter are also provided. | 03-10-2016 |
| 20160067384 | CATHETER SHAFT HAVING HIGH STRENGTH AND FLEXIBILITY - Elongated shaft for a catheter including a single layer biaxially oriented nonporous thermoplastic polymer tubular member having a Shore durometer hardness of less than about 75D is provided. Elongated shaft for a catheter prepared by a process is also provided. | 03-10-2016 |
| 20160058981 | NON-COMPLIANT MULTILAYERED BALLOON FOR A CATHETER - Multilayer balloon for a catheter includes at least a first layer, a second layer, and a third layer having a combined wall thickness. The first layer is made of a first polymer material having a first maximum blow-up-ratio. The second layer made of a second polymer material having a second maximum blow-up-ratio greater than the first maximum blow-up-ratio, and the second layer is an inner layer relative to the first layer. The third layer is made of a third polymer material having a third maximum blow-up-ratio greater than the second maximum blow-up-ratio, and the third layer is an inner layer relative to the second layer. The at least first, second, and third layers define a compliance less than that of a single layer balloon made of the first polymer material with a wall thickness equal to the combined wall thickness. Method of making of multilayer balloon is also provided. | 03-03-2016 |
| 20160051386 | Balloon Catheter Having Hydraulic Actuator - Catheter including an inner tubular member, an outer tubular member movable relative to the inner tubular member, and an expandable member coupled to the distal end portion of the inner tubular member. The expandable member having an inner chamber and transitionable between a deflated configuration and an inflated configuration. A pressure chamber is defined by the proximal seal, the distal seal, the exterior surface of the inner tubular member and interior surface of the outer tubular member, with the pressure chamber in fluid communication with a fluid flow port, wherein fluid introduced through the fluid flow port and into the pressure chamber applies a force on the proximal seal to urge the outer tubular member in a proximal direction. | 02-25-2016 |
| 20160038321 | Catheter Having Movable Tubular Structure And Proximal Stopper - Catheter including an inner tubular member, an outer tubular member movable relative to the inner tubular member, and a movable tubular structure coupled to the outer tubular member. A medical device disposed about a distal end portion of the inner tubular member. A proximal stopper is provided having a distal end and disposed proximal to a proximal end of the movable tubular structure. The distal end of the proximal stopper is spaced from the proximal end of the movable tubular structure at least a longitudinal length dimension of the medical device, wherein the outer tubular member and the movable tubular structure are movable in a proximal direction up to engagement of the proximal stopper to deploy the medical device from the inner tubular member. | 02-11-2016 |
| 20150343180 | MULTILAYER BALLOON FOR A CATHETER - Balloon catheter comprises an elongate catheter shaft having a proximal section, a distal section, and an inflation lumen defined therein and a multilayer balloon on the distal section of the shaft comprising a first layer made of a first polymer material having a first Shore durometer hardness, a second layer made of a second polymer material having a second Shore durometer hardness greater than the first Shore durometer hardness, wherein the second layer is an inner layer relative to the first layer, and a third layer made of a third polymer material having a third Shore durometer hardness less the first Shore durometer hardness, wherein the third layer is an inner layer relative to the second layer. Method of making a balloon catheter is also provided. | 12-03-2015 |
| 20150327871 | METHODS, SYSTEMS, AND DEVICES FOR TARGETING A RADIAL ACCESS PUNCTURE SITE - Methods, systems, and devices for applying targeted force to a radial access puncture site to aid in arresting bleeding at the puncture site. Such a device may include a cuff (e.g., band) for placement over a wrist of a patient, and an inflatable balloon attached to the cuff and disposed over the puncture site during use, such that the inflatable balloon applies pressure to the site during use. The device includes targeting indicia disposed on (i) the inflatable balloon, and/or (ii) an optional rigid or semi-rigid member (e.g., as a backing layer for the balloon). The targeting indicia identifies that portion of the balloon to be positioned on the puncture site so that the inflated balloon applies pressure to the site during use. An associated system may include a cuff device, and a fluid source from which an inflation fluid may be delivered into the inflatable balloon during use. | 11-19-2015 |
| 20150327870 | METHODS, SYSTEMS, AND DEVICES FOR APPLYING TARGET FORCE TO A RADIAL ACCESS PUNCTURE SITE - Systems and methods for applying targeted force to a radial access puncture site to provide hemostasis and close the puncture site. The system may include a cuff for placement over a wrist, a fluid source from which an inflation fluid may be delivered into an inflatable balloon associated with the cuff during use, and an inflatable balloon attached to the cuff. The balloon is disposed over the puncture site and inflated during use. The system may include one or more features configured to focus or target the applied force to the puncture site. For example, the balloon may include varying wall thickness, with a thinner-walled portion that applies a focused pressure to the puncture site, two balloons where one applies focused force, or an outer sheath with a hole placed over the balloon so that a portion of the balloon protrudes through the hole and applies focused force. | 11-19-2015 |
| 20150305899 | BRANCHED POLYHYDROXYALKANOATE SYSTEMS FOR BIORESORBABLE VASCULAR SCAFFOLD APPLICATIONS - An implantable medical devices such as a stent that includes sparse comb polyhydroxyalkanoate (PHA) systems is disclosed. The stent includes a stent body, scaffold, or substrate made partially or completely of polymer material including PHA. | 10-29-2015 |
| 20150297379 | SYSTEM FOR CONTINUOUS STENT ADVANCEMENT - A system for advancing a stent comprising a first stent-engaging member and a second stent-engaging member. The first stent-engaging member and the second stent-engaging member are each operably connected to a double crank, whereby, upon rotation of the double crank, the first stent-engaging member and the second stent-engaging member oscillate distally and proximally out of phase with each other. | 10-22-2015 |
| 20150297372 | RADIALLY EXPANDABLE POLYMER PROSTHESIS AND METHOD OF MAKING SAME - Polymeric stents having fracture toughness and resistance to recoil after deployment are disclosed along with methods of manufacturing such stents. Improvements to mechanical characteristics and other improvements may be achieved by having polymer chains within individual stent struts oriented in a direction that is closer to or in line with the axis of the individual stent struts. The struts are connected to each other by hinge elements that are configured to bend during crimping and deployment of the stent. Ring struts form ring structures. A ring structure can have an overall curvilinear length from about 12 mm to about 15 mm. | 10-22-2015 |
| 20150290435 | NON-COMPLIANT MULTILAYERED BALLOON FOR A CATHETER - Balloon catheter comprises an elongate catheter shaft having a proximal section, a distal section, and an inflation lumen, and a multilayer balloon on the distal section of the shaft. The multilayer balloon comprises a first layer made of a first polymer material having a first Shore durometer hardness, a second layer made of a second polymer material having a second Shore durometer hardness lower than the first shore durometer hardness, wherein the second layer is an inner layer relative to the first layer, and an outer-most layer made of a third polymer material having a third Shore durometer hardness lower than the second Shore durometer hardness. | 10-15-2015 |
| 20150289875 | INTRAVASCULAR DEVICES SUPPORTING AN ARTERIOVENOUS FISTULA - Medical devices and methods for forming an arteriovenous (AV) fistula include a stent having an arterial tubular portion and vein supporting tongue connected by a pre-shaped connector and a venous frustoconical stent having a distal end for maintaining a take-off angle for the venous portion of the AV fistula. Also disclosed is an angled balloon for assisting with the formation of the AV fistula. The medical devices disclosed herein support an AV fistula formation having a desired take off angle of about 30 degrees, or between about 15 and 45 degrees. | 10-15-2015 |
| 20150257910 | STRIPED SHEATHS FOR MEDICAL DEVICES - A sheath used to protect a medical device has one or more strips formed over a portion thereof. The medical device is a scaffold crimped to a balloon and mounted to a catheter. The sheath is two-piece, including a protecting and constraining sheath part. The strips facilitate removal of the constraining sheath from the scaffold in manner that reduces instances of damage caused by improper removal of the sheath from the medical device. | 09-17-2015 |
| 20150246203 | PROTECTIVE SHEATHS FOR MEDICAL DEVICES - A process for making a sheath used to protect a medical device. The medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. A sheath is placed over the crimped scaffold after crimping to reduce recoil of the crimped polymer scaffold and maintain scaffold-balloon engagement relied on to hold the scaffold to the balloon when the scaffold is being delivered to a target in a body. The sheath is removed by a health professional either by removing the sheath directly or using a tube containing the catheter. | 09-03-2015 |
| 20150245937 | CATHETER HAVING HYDRAULIC ACTUATOR - Catheter for delivery of a medical device such as a stent or filter includes an inner tubular member and an outer tubular member movable relative to the inner tubular member. The outer tubular member is disposed at the distal end of the inner tubular member. The inner tubular member includes a fluid lumen defined therein, the fluid lumen having a fluid flow port directed to the exterior surface of the inner tubular member. A pressure chamber is defined by the inner tubular member, the outer tubular member, a proximal seal and a distal seal, and is in fluid communication with the fluid flow port, wherein fluid introduced through the fluid flow port and into the pressure chamber applies a force on the proximal seal to move the outer tubular member in a proximal direction allowing the medical device constrained by the outer tubular member to be released. | 09-03-2015 |
| 20150238737 | BALLOON CATHETER SHAFT HAVING HIGH STRENGTH AND FLEXIBILITY - Method of making a balloon catheter includes melt-extruding a thermoplastic polymeric material into a tube, cooling the extruded tube, placing the extruded tube within a capture member and biaxially orienting the polymeric material of the extruded tube while simultaneously tapering at least a section of the extruded tube by radially expanding the extruded tube with pressurized media in the tube lumen and axially expanding the extruded tube with an external load applied on at least one end of the tube as an external heat supply traverses longitudinally from a first end to a second end of the extruded tube in the capture member, wherein an overall axial load on the tubing is varied as at least a section of the tube is heated. The method includes cooling the expanded tube to form a tapered biaxially oriented nonporous thermoplastic polymer tubular member and sealingly securing a balloon proximate a distal end of the tubular member. | 08-27-2015 |
| 20150196690 | COATINGS WITH TUNABLE MOLECULAR ARCHITECTURE FOR DRUG-COATED BALLOON - A drug delivery balloon is provided, the a balloon having an outer surface, and a tunable coating disposed on at least a length of the balloon surface. The tunable coating includes a first therapeutic agent and a first excipient, wherein the cytostatic therapeutic agent and the at least one excipient have a weight ratio of about 20:1 to about 1:20, and further wherein the coating provides increased efficiency of therapeutic transfer to a body lumen. | 07-16-2015 |
| 20150182223 | INDEPENDENT GRIPPER - The invention provides devices, systems and methods for tissue approximation and repair at treatment sites. The devices, systems and methods of the invention will find use in a variety of therapeutic procedures, including endovascular, minimally-invasive, and open surgical procedures, and can be used in various anatomical regions, including the abdomen, thorax, cardiovascular system, heart, intestinal tract, stomach, urinary tract, bladder, lung, and other organs, vessels, and tissues. The invention is particularly useful in those procedures requiring minimally-invasive or endovascular access to remote tissue locations, where the instruments utilized must negotiate long, narrow, and tortuous pathways to the treatment site. In addition, many of the devices and systems of the invention are adapted to be reversible and removable from the patient at any point without interference with or trauma to internal tissues. | 07-02-2015 |
| 20150157475 | DEFLECTOR FOR INCREASED WALL SHEAR STRESS ADJACENT AN ARTERIOVENOUS FISTULA - A medical device includes an elongate body having a distal and proximal end, a pair of anchors at the distal end and spacers extending along its length. The body is delivered to an AV fistula using a catheter connected to the proximal end by a tether. The body when deployed at the fistula is suspended within the flow stream and spaced from walls of a blood vessel. The body deflects blood flow to cause an increase in vascular wall shear stress, which has been found to induce a positive vascular remodeling. | 06-11-2015 |
| 20150119976 | EXTRAVASCULAR DEVICE FOR LIMITING BLOOD FLOW ADJACENT AN ARTERIOVENOUS FISTULA - A medical device that can be wrapped around a segment of an artery downstream of an arteriovenous fistula. The wrap, when used in this manner, creates a stenosis for reducing retrograde flow at the fistula. Sutures are positioned in holes present in the upper and lower halves or connecting ends of the wrap, after which the sutures are pulled to oppose the two sides in order to create a stenosis. When the surgeon is satisfied that the stenosis is appropriate, the sutures are tied in place. | 04-30-2015 |
| 20150119908 | EXTRAVASCULAR DEVICES SUPPORTING AN ARTERIOVENOUS FISTULA - A medical device includes a curved tubular body configured for being used as an extravascular device to support vein maturation following the formation of an arteriovenous fistula. The tubular body is curved. The tubular body has an entrance angle of less than about 40 degrees to improve blood flow from the artery into the vein. And the tubular body includes a cuff or edge at the proximal end to stabilize the tubular body at the fistula. | 04-30-2015 |
| 20150112210 | LUMEN BASED PRESSURE MEASUREMENT GUIDE WIRE SYSTEM FOR MEASURING PRESSURE IN A BODY LUMEN - A medical system utilizes a guide wire with a fluid filled internal lumen and a pressure measurement system to measure blood pressure in a body vessel. The guide wire includes an internal lumen with a distal opening for admitting fluid flow. The internal lumen is filled with a fluid or other media which can transmit pressure along the guide wire. The pressure measurement system includes a pressure transducer in fluid communication with the internal lumen of the guide wire. Pressure waveform in the body vessel are transmitted through the fluid or media from the distal opening of the internal lumen to the pressure transducer. The pressure transducer is in communication with a processor (with display) for determining the pressure acting on the pressure transducer. A pump with a fluid reservoir in fluid communication with the internal lumen of the guide wire is controlled by the processor. The pump introduces additional fluid into the guide wire lumen. | 04-23-2015 |
| 20150105805 | SUTURE-BASED CLOSURE WITH HEMOSTATIC TRACT PLUG - Devices for closing a passage through tissue communicating with a body lumen. The device may include an elongate body, a sheath disposed at the distal end of the device for disposition within a body lumen, a hollow needle disposed within a needle lumen of the body, the needle being selectively advancable through the needle lumen, a suture-anchor ejection mandrel disposed within the hollow needle that is also selectively advancable through the hollow needle, a suture-anchor and suture disposed within the hollow needle, a distal end of the suture attached to the suture anchor for ejection out the hollow needle by the mandrel. A needle guide disposed between the sheath and proximal end of the body may include a needle port through which the needle can exit. A hemostatic plug is disposed over the needle port so as to be penetrated by the needle upon exiting the port. | 04-16-2015 |
| 20150105804 | GRIPPER PUSHER MECHANISM FOR TISSUE APPOSITION SYSTEMS - The invention provides devices, systems and methods for tissue approximation and repair at treatment sites. The devices, systems and methods of the invention will find use in a variety of therapeutic procedures, including endovascular, minimally-invasive, and open surgical procedures, and can be used in various anatomical regions, including the abdomen, thorax, cardiovascular system, heart, intestinal tract, stomach, urinary tract, bladder, lung, and other organs, vessels, and tissues. The invention is particularly useful in those procedures requiring minimally-invasive or endovascular access to remote tissue locations, where the instruments utilized must negotiate long, narrow, and tortuous pathways to the treatment site. In addition, many of the devices and systems of the invention are adapted to be reversible and removable from the patient at any point without interference with or trauma to internal tissues. | 04-16-2015 |
| 20150096491 | MAINTAINING A FIXED DISTANCE DURING COATING OF DRUG COATED BALLOON - A system and method for coating an expandable member of a medical device comprising a support structure to support the expandable member and a dispenser positioned with at least one outlet proximate a surface of an expandable member. A drive assembly establishes relative movement between the at least one outlet and the surface of the expandable member to apply fluid on the surface of the expandable member along a coating path. A guide maintains a substantially fixed distance between the at least one outlet and the surface of the expandable member during relative movement therebetween by displacing the expandable member relative to the at least one outlet. | 04-09-2015 |
| 20150088240 | CLIP SHEATH FOR A POLYMER SCAFFOLD - A sheath is placed over a crimped scaffold to reduce recoil of the crimped polymer scaffold and maintain scaffold-balloon engagement relied on to hold the scaffold to the balloon when the scaffold is being delivered to a target in a body. The sheath has an opening spanning the length of the sheath. The opening spans an arc length of about 90 degrees with respect to the circumference of the scaffold or balloon. The sheath may be removed from the scaffold by pinching the sheath between a thumb and forefinger, or bending or peeling back the sheath from the edges of the opening using fingertips. | 03-26-2015 |
| 20150045877 | REGIONAL DELIVERY OF THERAPEUTIC AGENTS FOR THE TREATMENT OF VASCULAR DISEASES - The present invention relates to the regional delivery of therapeutic agents for the treatment of vascular diseases wherein regional delivery refers to delivery of a therapeutically effective amount of the therapeutic agent to an area of the vessel that includes not only afflicted tissue but non-afflicted tissue at the periphery of the afflicted tissue as well. | 02-12-2015 |
| 20150039075 | VARIABLE STIFFNESS STENT - A stent has one or more redundant crests for a ring. The redundant crest is located at a Y-crown for a peak-to-valley type stent pattern in one example. The stent may also have frangible bridges for connecting links. The stent's radial stiffness decreases when a redundant crest fractures and its axial and bending stiffness decreases when a frangible bridge breaks. | 02-05-2015 |
| 20140348800 | MODIFIED TWO-COMPONENT GELATION SYSTEMS, METHODS OF USE AND METHODS OF MANUFACTURE - A bioscaffolding can be formed from a mixture of gel components of different gelation systems. For example, a bioscaffolding can be formed by mixing at least two different components of at least two different two-component gelation systems to form a first mixture and by mixing at least two different components (other than the components that make up the first mixture) of the at least two different two-component gelation systems to form a second mixture. A treatment agent, such as a cell type or a growth factor, can be added to either the first mixture or the second mixture. In some embodiments, the treatment agent is not added to either mixture. The first mixture can be co-injected with the second mixture to form a bioscaffolding in an infarct region for treatment thereof. | 11-27-2014 |
| 20140336619 | OPHTHALMIC SHUNT AND METHOD - An ophthalmic shunt includes a seal or septum through which multiple injections of the therapeutic agent can be made as needed, thereby avoiding repeated injury to the sclera. The therapeutic agent is temporarily carried in a tube connected to the septum. The therapeutic agent release may be rapid or sustained over a period of time. | 11-13-2014 |
| 20140335143 | Polymer Blends For Drug Delivery Stent Matrix With Improved Thermal Stability - Various embodiments of the present invention generally relate to a polymer blend composition used for coating a medical device that exhibits improved thermal stability. The invention also encompasses implantable medical devices coated the aforementioned coating. | 11-13-2014 |
| 20140323965 | MEDICAL DEVICE SYSTEM AND METHOD FOR PUSHABILITY - Medical device system comprising a catheter including an elongate tubular member having an inner wall surface defining a lumen extending longitudinally through at least a portion of the tubular member. The medical device also includes an inner stop extending inwardly from the inner wall surface of the tubular member at a distal end section of the catheter and a pusher device insertable into the lumen. The pusher device has a contact surface to abut the inner stop of the tubular member. | 10-30-2014 |
| 20140319724 | BIOABSORBABLE SCAFFOLD WITH PARTICLES PROVIDING DELAYED ACCELERATION OF DEGRADATION - Methods of controlling the degradation profile of a biodegradable stent scaffolding are disclosed. A bioabsorbable scaffold having a plurality of particles incorporated into the scaffolding that accelerate the absorption of the scaffolding after an induction time during degradation is disclosed. | 10-30-2014 |
| 20140288628 | METHOD TO MINIMIZE CHAIN SCISSION AND MONOMER GENERATION IN PROCESSING OF POLY(L-LACTIDE) STENT - Methods of fabricating an implantable medical devices such as stents made from biodegradable polymers are disclosed that reduce or minimize chain scission and monomer generation during processing steps. The method includes processing a poly(L-lactide) resin having an number average molecular weight between 150 to 200 kD in an extruder in a molten state. A poly(L-lactide) tube is formed from the processed resin and a stent is fabricated from the tube. The number average molecular weight of the poly(L-lactide) of the stent after sterilization is 70 to 100 kD. | 09-25-2014 |
| 20140277398 | DRUG DELIVERY DEVICE FOR PERIPHERAL ARTERY DISEASE - A medical device implantable within a peripheral vessel of the body composed of a bioresorbable polymer is disclosed. The device has a high resistance to fracture, is very flexible, and has a high crush recovery when subjected to crushing, axial, or torsional forces. | 09-18-2014 |
| 20140277392 | ELECTROPOLISHING OF ALLOYS CONTAINING PLATINUM AND OTHER PRECIOUS METALS - Radiopaque cobalt-based alloys having a smooth electropolished surface with rounded edges and methods for electropolishing such alloys. A cobalt-based alloy includes cobalt, chromium, and one or more radiopaque elements. In one embodiment, examples of radiopaque elements include so-called platinum group metals (i.e., platinum, palladium, ruthenium, rhodium, osmium, or iridium). Group 10 elements (i.e., platinum or palladium) are particularly preferred. Because of the presence of the platinum group metal(s), such alloys are generally difficult to electropolish. Electrolyte formulations and methods for electropolishing such alloys are also disclosed. | 09-18-2014 |
| 20140277372 | Polymer Scaffolds Having Enhanced Axial Fatigue Properties - A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. The scaffold has a morphology resulting from a biaxially expanded tube arranged to provide a more balanced, or less anisotropic axial and radial mechanical properties. The scaffold has improved mechanical properties suited for use as a balloon expandable scaffold implanted in a peripheral vessel of the body. | 09-18-2014 |
| 20140277356 | CATHETER HAVING HYDRAULIC ACTUATOR AND LOCKING SYSTEM - Catheter including a pressure chamber defined by proximal and distal seals and inner and outer tubular members. An actuator member, moveable between first and second positions, is disposed within the pressure chamber. Fluid introduced into the pressure chamber applies a force on the actuator member to move the actuator member toward the second position. A lock mechanism, disposed between inner and outer tubular members, includes a latch having an engaged condition preventing movement of the outer tubular member relative the inner member and a disengaged condition allowing movement the outer member. The latch is shifted to the disengaged condition when the actuator member is moved to the second position. With the actuator member in the second position and the latch in the disengaged condition, fluid introduced through the fluid flow port and into the pressure chamber applies a force on the proximal seal to urge the outer tubular member proximally. | 09-18-2014 |
| 20140277343 | DRUG DELIVERY DEVICE, METHOD, AND SYSTEM FOR ADMINISTRATION OF DUAL ANTIPLATELET THERAPY - A drug delivery device for reducing the likelihood of stent thrombosis following implantation in a subject is provided. A stent is provided including a body having a plurality of struts and one or more coatings applied to the body including at least one polymer, a therapeutic agent for inhibiting restenosis, a loading dose of a first antiplatelet agent and a maintenance dose of the first antiplatelet agent, and a loading dose of a second antiplatelet agent and a maintenance dose of the second antiplatelet agent. | 09-18-2014 |
| 20140277331 | Reducing Recoil in Peripherally-Implanted Scaffolds - A peripherally implanted polymer scaffold having a high degree of recoil is worked to reduce recoil in the scaffold when initially deployed at a target lesion in the body. The scaffold is plastically deformed from a crimped state to an expanded state by a balloon catheter. The scaffold is contained within a sheath to prevent recoil up until the point of use. Before the scaffold is introduced to the body, the restraining sheath is removed from the scaffold. | 09-18-2014 |
| 20140277077 | FILTER WITH DEPLOYABLE ANCHORS - An implantable and removable filter that may be implanted in and/or removed from a body lumen, such as the Vena Cava. The filter including tissue anchors on expandable anchoring legs, which can be selectively moved between a non-anchoring or pre-deployed configuration into an anchoring or deployed configuration by obturators that are movable inside the anchoring legs. | 09-18-2014 |
| 20140276608 | BALLOON SCLEROTHERAPY - Disclosed are methods, devices, and systems for treating a body lumen with a sclerothepeutic agent. The method includes the steps of positioning a porous balloon assembly at a site in the lumen to be treated, inflating the assembly to establish a close approximation to the lumen wall, forcing the sclerotherapeutic agent to exit the pores and come in contact with the lumen wall, and to deflate and retrieve the balloon assembly. The methods, devices and systems disclosed herein are especially useful for the treatment of incompetent veins and their contributory branches. | 09-18-2014 |
| 20140276585 | LENGTH ADJUSTABLE BALLOON CATHETER FOR MULTIPLE INDICATIONS - Adjustable balloon catheter including an inner tubular member that has an inflation lumen. An expandable member is coupled to the distal end portion of the inner tubular member and has an inner chamber in fluid communication with the inflation lumen. The expandable member is transitionable between a deflated and an inflated configuration. The expandable member defines has a non-cylindrical shape including a first section having a first diameter in the inflated configuration and a second section having a second diameter when in the inflated configuration. The first diameter is different than the second diameter. An outer tubular member is movable relative to the inner tubular member. The outer tubular member is moveable between an extended position disposed over the expandable member and a fully retracted position proximal to the extended position. The outer tubular member is selectively positioned between the extended position and the fully retracted position. | 09-18-2014 |
| 20140276401 | Catheter Shaft and Method of Forming Same - Elongate, flexible catheter includes an elongated shaft having a proximal end, a distal end, and a lumen defined therein. The shaft includes a tubular member having an outer layer and an inner layer. The outer layer includes a first polymer selected from the group consisting of nylon 12, polyether block amide, and combinations thereof. The inner layer includes a second polymer having a heat deflection temperature greater than about 53° C. selected from the group consisting of nylon 11, nylon 6, nylon 6,6, nylon 6,12, polyamide-imide, polyetherimide, polypropylene, polyethylene terephthalate, polybutylene terephthalate, polyethereetherketone, and combinations thereof. Method of making an elongate, flexible catheter is also provided. | 09-18-2014 |
| 20140276400 | Reduced Material Tip for Catheter and Method of Forming Same - Method for fabricating a catheter including providing an inner tubular member formed from a first polymeric material, the inner tubular member having a distal section, a distal end, and a lumen defined therein by a first inner diameter; necking down at least a portion of the distal section of the inner tubular member to form a necked tip having a second inner diameter; and removing a portion of polymeric material from an inner surface along the necked tip to define a third inner diameter for the necked tip. The method can include positioning the distal section of the inner tubular member in a balloon having a working length, a distal neck, and a distal leg, with the distal end of the inner tubular member extending distally beyond a distal end of the distal leg, and coupling the distal leg of the balloon to at least a portion of the distal section of the inner tubular member. | 09-18-2014 |
| 20140265060 | DEFORMATION OF A POLYMER TUBE IN THE FABRICATION OF A MEDICAL ARTICLE - Methods of manufacturing a medical article that include radial deformation of a polymer tube are disclosed. A medical article, such as an implantable medical device or an inflatable member, may be fabricated from a deformed tube. | 09-18-2014 |
| 20140263220 | LASER CUTTING PROCESS MONITORING AND CONTROL - A laser system including various optical components providing for beam alignment and process monitoring of a stent cutting process is described. The various aspects of the invention provide for monitoring of a beam of laser light reflected from the surface of a stent tube so as monitor the properties of the cutting beam, location of the beam, system cleanliness, optical defects in the system, and cutting efficiency of the laser. | 09-18-2014 |
| 20140263219 | LASER OPTICS WITH LATERAL AND ANGULAR SHIFT COMPENSATION - A telecentric F-theta lens is added to the optical chain of a laser used to cut stent patterns into a stent tube to facilitate positioning and alignment of the laser beam and to compensate for lateral and angular shift of the beam spot. | 09-18-2014 |
| 20140263217 | SHORT PULSE LASER MACHINING OF POLYMERS ENHANCED WITH LIGHT ABSORBERS FOR FABRICATING MEDICAL DEVICES - A method of laser machining a polymer construct to form a stent that includes a bioresorbable polymer and an absorber that increases absorption of laser energy during laser machining. The laser cuts the tubing at least in part by a multiphoton absorption mechanism and the polymer and absorber have a very low absorbance or are transparent to light at the laser wavelength. | 09-18-2014 |
| 20140255451 | Implantable Medical Device Comprising A Macrocyclic Triene Lactone Drug And Minimal Antioxidant Stabilizer And Method Of Fabrication - The present invention relates to an oxygen-sensitive macrocyclic triene lactone that is protected by addition of an appropriate amount of an antioxidant stabilizer during fabrication of an implantable medical device comprising the macrocyclic triene lactone, wherein the amount of the antioxidant stabilizer has been reduced to a minimal, preferably, non-detect, level in the final packaged product. | 09-11-2014 |
| 20140252683 | SURFACE TREATMENT OF A POLYMERIC STENT - Methods of treating the polymeric surfaces of a stent with a fluid including a solvent for the surface polymer are disclosed. | 09-11-2014 |
| 20140252675 | MEDICAL DEVICE FABRICATION PROCESS INCLUDING STRAIN INDUCED CRYSTALLIZATION WITH ENHANCED CRYSTALLIZATION - Methods of fabricating a polymeric implantable device, such as a stent, with improved fracture toughness through annealing a polymer construct below the glass transition temperature of the polymer of the construct prior to a deformation step are disclosed herein. The deformation of the construct induces crystallization in the polymer construct through strain-induced crystallization. The annealing of the polymer construct accelerates the crystallization induced during the deformation and results in an increase in crystallite density with smaller crystallites as compared to deformation of a tube that has not been annealed. A stent scaffolding is then made from the deformed tube. | 09-11-2014 |
| 20140251536 | METHODS FOR MANUFACTURING A CATHETER USING AN ALUMINUM NITRIDE BONDING APPARATUS - Apparatuses and methods for joining one or more tubing sections together to form a tubular catheter device, for shaping one or more tubular sections of a catheter device, and/or for fusing elements (e.g., a radiopaque marker) onto a portion of the catheter. Each section of the catheter is typically fabricated independently from the other sections. Subsequently, the separate sections are fused together to form the catheter. The methods described herein allow the various sections of the catheter to be fitted together for fabrication without the use of heat-shrink tubing. The fitted parts are clamped in a die or mold at a temperature at or near room temperature; the die is then rapidly heated to fuse the parts, rapidly cooled back down to a temperature at or about room temperature, and removed from the die. | 09-11-2014 |
| 20140250836 | Method Of Fabricating An Implantable Medical Device Comprising A Rapamycin Derivative - This invention relates to an method of manufacture of an implantable medical device comprising an oxygen-sensitive rapamycin derivative that is protected by addition of an antioxidant during the manufacturing process where the amount of antioxidant added at the outset of the processing is such that when the device is fully fabricated, sterilized and packaged the amount of antioxidant has reduced to a minimal, preferably non-detect, amount. | 09-11-2014 |
| 20140250667 | METHODS FOR CRIMPING A POLYMERIC STENT SCAFFOLD ONTO A DELIVERY BALLOON - A medical device includes a polymer stent scaffold crimped to a catheter having an expansion balloon. A process for forming the medical device includes placing the scaffold on a support supported by an alignment carriage, and deionizing the scaffold to remove any static charge buildup on the scaffold before placing the scaffold within a crimper to reduce the scaffold's diameter. The polymer scaffold is heated to a temperature below the polymer's glass transition temperature to improve scaffold retention without adversely affecting the mechanical characteristics of the scaffold when deployed to support a body lumen. | 09-11-2014 |
| 20140249475 | APPARATUS FOR TREATING VULNERABLE PLAQUE - Embodiments include a medical device having a balloon portion with a first end, a second end, and a variable balloon mass to inflate the balloon portion non-uniformly from the first end to the second end. In one embodiment, the balloon portion inflates in a controlled manner to rupture a vulnerable plaque near the second end. | 09-04-2014 |
| 20140246407 | GUIDE WIRE WITH CORE HAVING WELDED WIRE SEGMENTS - An intravascular guide wire having two core materials joined together without the use of a connector tube or sleeve, the core materials being stainless steel and psuedoelastic metal alloy, nitinol. The core materials are joined to each other through an intermediate transition piece made essentially of nickel, which is welded on either side to the two core materials. In a multi-segment intravascular guide wire, discrete, high modulus and medium modulus core portions of different materials are welded to a shapeable, low modulus distal core portion made of a third material having a flattened, shapeable section at a most distal end that is not welded to but made from the distal core portion, so the flattened, shapeable section can be deformed to create a steerable tip. Processes such as simultaneous resistance and friction welding can be used to join the core portions. | 09-04-2014 |
| 20140246120 | SUCTION PUMP AND APPARATUS FOR LOADING MATERIAL INTO A STENT STRUT - An apparatus for loading material into a stent strut can comprise a suction pump connected to an opening to a lumen within the stent strut. The stent strut is immersed in the material. As the suction pump draws gas out of the lumen, the material is drawn into side openings to the lumen. | 09-04-2014 |
| 20140243947 | THERMOELASTIC AND SUPERELASTIC NI-TI-W ALLOY - A radiopaque nitinol stent for implantation in a body lumen is disclosed. The stent is made from a superelastic alloy such as nickel-titanium or nitinol, and includes a ternary element including tungsten. The added tungsten in specified amounts improve the radiopacity of the nitinol stent comparable to that of a stainless steel stent of the same strut pattern coated with a thin layer of gold. Furthermore, the nitinol stent has improved radiopacity yet retains its superelastic and shape memory behavior and further maintains a thin strut/wall thickness for high flexibility. | 08-28-2014 |
| 20140242257 | FIBER REINFORCED COMPOSITE STENTS - Polymeric composite stents reinforced with fibers for implantation into a bodily lumen are disclosed. | 08-28-2014 |
| 20140242165 | Biocompatible Carrier Containing A Bioadhesive Material - A biocompatible carrier for delivery of a therapeutic substance or an active agent is disclosed. The carrier contains a bioadhesive material allowing for increased residence time of the active agent at the treatment site. | 08-28-2014 |
| 20140242144 | DRUG ELUTING SCAFFOLD FOR KIDNEY-RELATED DISEASE - Methods of treating renal cancers and other kidney-related inflammatory disorders with a bioabsorbable polymer scaffold (such as a stent) are described. The treatments are provided as alternative to complete or partial surgical removal of a diseased kidney. | 08-28-2014 |
| 20140239558 | SYSTEM FOR MANUFACTURING A POLYMER ENDOPROSTHESIS BY INJECTION MOLDING AND BLOW MOLDING - A polymer endoprosthesis is fabricated by a combination of injection molding and blow molding which form a tubular substrate of polymer material, followed by laser cutting, crimping and sterilization. After the injection and blow molding processes, a subtractive process is performed on the tubular substrate to transform it into a stent having a network of stent struts. The tubular substrate can be made in an injection mold and blow mold which are attached to each other. The transition from injection molding and blow molding can be performed while the injection molded substrate remains at a temperature at or above Tg of the polymer material. | 08-28-2014 |
| 20140238535 | COVER SLEEVE AND APPARATUS FOR LOADING MATERIAL INTO A STENT STRUT - An apparatus for loading material into a stent strut can comprise a cover sleeve. The cover sleeve is elastic so that it can reduce in diameter so as to press against the stent strut, and expand in diameter so as to be spaced apart from the stent strut. The stent strut can include a lumen into which material is injected. When pressed against the stent strut, the cover sleeve seals side openings to the lumen and prevents injected material from leaking out of the side openings during the injection process. | 08-28-2014 |
| 20140238293 | Crimping Apparatus - An apparatus is disclosed including a workspace for receiving a stent and a delivery device for the stent; a source for exposing the stent in the workspace to a plasticizing agent, vapor, or moisture, wherein the stent can be reduced in diameter in the workspace while under exposure of the plasticizing agent, vapor or moisture; and a device for reducing the diameter of the stent in the workspace to position the stent on or within the delivery device. | 08-28-2014 |
| 20140237801 | STENT WITH RADIOPAQUE MARKERS - Various embodiments of stents with radiopaque markers arranged in patterns are described herein. | 08-28-2014 |
| 20140236188 | INTRODUCER SHEATH WITH KNOT PUSHER AND SUTURE TRIMMER - A device configured as a knot pusher and/or a suture trimmer is provided. The device can deliver and secure a suture knot. The apparatus can also trim the suture after the suture knot is secured. | 08-21-2014 |
| 20140236082 | Biocompatible Carrier Containing A Bioadhesive Material - A biocompatible carrier for delivery of a therapeutic substance or an active agent is disclosed. The carrier contains a bioadhesive material allowing for increased residence time of the active agent at the treatment site. | 08-21-2014 |
| 20140234164 | POST ELECTRON BEAM STABILIZATION OF POLYMERIC MEDICAL DEVICES - Methods are disclosed for chemically stabilizing a polymer stent after sterilization. The stent is exposed to a temperature above ambient for a period of time after radiation sterilization. The exposure reduces the concentration of free radicals generated by the radiation. | 08-21-2014 |
| 20140230373 | REDUCED TEMPERATURE STERILIZATION OF STENTS - Methods and systems for reduced temperature radiation sterilization of stents are disclosed. | 08-21-2014 |
| 20140230227 | METHODS FOR CRIMPING A POLYMERIC SCAFFOLD TO A DELIVERY BALLOON AND ACHIEVING STABLE MECHANICAL PROPERTIES IN THE SCAFFOLD AFTER CRIMPING - A medical device-includes a polymer scaffold crimped to a catheter having an expansion balloon. The scaffold is crimped to the balloon by a process that includes inflating the delivery balloon during a diameter reduction to improve scaffold retention. A crimping temperature is maintained at about the onset of glass transition of the polymer material to facilitate more rapid stabilization of mechanical properties in the scaffold following crimping. | 08-21-2014 |
| 20140230225 | MOUNTING STENTS ON STENT DELIVERY SYSTEMS - A system for mounting a stent on a balloon catheter includes two positioning and alignment stations, which are used to prepare a stent and catheter for crimping using the same crimping head. The system is configured for automated assembly of the stent and catheter prior to crimping. A catheter and stent are placed on a computer-controlled carriage that delivers the stent and catheter to the crimper head. Before placing the stent and catheter into the crimper head, an automated alignment system locates the stent between balloon markers. | 08-21-2014 |
| 20140221418 | HYALURONIC ACID BASED COPOLYMERS - Hyaluronic acid (HA) conjugates or crosslinked HAs compositions for coating an implantable device are provided. The implantable device can be used for treating a disorder such as atherosclerosis, thrombosis, restenosis, high cholesterol, hemorrhage, vascular dissection or perforation, vascular aneurysm, vulnerable plaque, chronic total occlusion, claudication, anastomotic proliferation for vein and artificial grafts, bile duct obstruction, ureter obstruction, tumor obstruction, and combinations thereof. | 08-07-2014 |
| 20140219863 | SYSTEM FOR RADIATION STERILIZATION OF MEDICAL DEVICES - A method for medical device sterilization comprises staggering a stack of packages so that a back surface of each package partially overlaps a front surface of another of the packages. Each package contains a medical device. The stack of packages are positioned so that the front surfaces of the packages face toward a radiation source. The packages are then exposed to radiation. | 08-07-2014 |
| 20140213967 | Balloon Catheter Shaft Having High Strength and Flexibility - Balloon catheter comprises an elongated shaft having a proximal end and a distal end, the elongated shaft including a biaxially oriented nonporous thermoplastic polymer tubular member having a Shore durometer hardness of less than about 75D with an inflation lumen defined therein. The balloon catheter also comprises a balloon sealing secured proximate the distal end of the shaft and having an interior in fluid communication with the inflation lumen. | 07-31-2014 |
| 20140212476 | Method of Targeting Hydrophobic Drugs to Vascular Lesions - This invention relates to the targeted delivery of hydrophobic drugs or combinations of hydrophobic drugs with photodynamic therapy agents to vascular lesions by complexation of the drugs to blood serum lipoproteins, which have an affinity for and accumulate in such vascular lesions. | 07-31-2014 |
| 20140212355 | TRANS-ARTERIAL DRUG DELIVERY - It is provided herein methods, devices, and compositions for trans-arterial local delivery of therapeutic agent for the treatment of liver cancers. | 07-31-2014 |
| 20140207161 | GRIPPER PUSHER MECHANISM FOR TISSUE APPOSITION SYSTEMS - The invention provides devices, systems and methods for tissue approximation and repair at treatment sites. The devices, systems and methods of the invention will find use in a variety of therapeutic procedures, including endovascular, minimally-invasive, and open surgical procedures, and can be used in various anatomical regions, including the abdomen, thorax, cardiovascular system, heart, intestinal tract, stomach, urinary tract, bladder, lung, and other organs, vessels, and tissues. The invention is particularly useful in those procedures requiring minimally-invasive or endovascular access to remote tissue locations, where the instruments utilized must negotiate long, narrow, and tortuous pathways to the treatment site. In addition, many of the devices and systems of the invention are adapted to be reversible and removable from the patient at any point without interference with or trauma to internal tissues. | 07-24-2014 |
| 20140206614 | Compositions for Achieving a Therapeutic Effect in an Anatomical Structure - Compositions and methods of using the compositions are provided for forming an embolus within a region of an anatomical lumen for a transitory period in order to achieve a therapeutic effect. | 07-24-2014 |
| 20140205740 | Coated Stent and Method of Making the Same - A coated implantable medical device and a method of coating an implantable medical device is disclosed, the method includes applying a composition onto the device and drying the composition at elevated temperature in an environment having increased relative humidity. A pre-screening method for a manufacturing lot of coated stents to determine the number of drug coating layers for a desired drug release rate is disclosed. The method including coating and testing small groups of stents, and applying the results of the tests to determine the number of drug coating layers to apply to the manufacturing lot of stents. | 07-24-2014 |
| 20140201973 | METHODS FOR UNIFORM CRIMPING AND DEPLOYMENT OF A POLYMER SCAFFOLD - A medical device-includes a scaffold crimped to a catheter having an expansion balloon. The scaffold is crimped to the balloon by a process that includes one or more balloon pressurization steps. The balloon pressurization steps are selected to enhance scaffold retention to the balloon while retaining, at least partially, the original balloon folds as the balloon is pressurized and de-pressurized within a crimper head. By at least partially retaining the original balloon folds, a uniformity of scaffold expansion by the balloon is improved. | 07-24-2014 |
| 20140200655 | INTRAVASCULAR CARDIAC RESTRAINING IMPLANTS AND METHODS FOR TREATING HEART FAILURE - Intravascular cardiac restraining implants designed for treatment of heart disease and heart failure and methods for their use. The disclosed implants can be used to reshape or reinforce a diseased, weakened or distended portion of a patient's heart to counteract heart disease and heart damage. An intravascular cardiac restraining implant may include a first tissue anchor configured for implantation in a first region of a coronary vein, a second tissue anchor configured for implantation in a second region of the coronary vein, and at least one elongate member coupled to the first tissue anchor and the second tissue anchor. In one embodiment, the at least one elongate member may be a spring or a similar device configured for biasing the first and second tissue anchors toward one another, thus reshaping or reinforcing a diseased, weakened or distended portion of a patient's heart. | 07-17-2014 |
| 20140200647 | STENT WITH ENHANCED PROFILE - A stent for implantation in a body lumen, comprising a plurality of rings, each ring being connected to an adjacent ring by at least one link, each ring including a plurality of peaks and valleys, wherein each peak is connected to an adjacent valley by a strut to provide an undulating pattern within each ring. Further, wherein each of a plurality of the struts comprise a first portion and a second portion; each portion has a thickness that is substantially constant throughout both first and second portions; and each portion has a width that is substantially constant throughout both first and second portions. The first portion is connected to the second portion through a reduced zone positioned at a mid-point of the strut, wherein the reduced zone has a minimum thickness between 30% and 80% of the thickness of the first and second portions. | 07-17-2014 |
| 20140200555 | METHODS FOR COUNTERACTING REBOUNDING EFFECTS DURING SOLID STATE RESISTANCE WELDING OF DISSIMILAR MATERIALS - The present disclosure is directed to methods for joining initially separate members of different metallic materials, e.g., as in joining segments of a multi-segment intravascular guide wire, as well as multi-segment intravascular guide wires so formed. Initially separate members are provided, which members comprise different metallic materials relative to one another (e.g., stainless steel and nitinol). The members are aligned with one another, and a first force is applied to the members while delivering electrical current through the members to solid state weld the separate members to one another. A follow up force that is greater than the first force is applied as solid-state deformation occurs and a weld nugget forms between the members. The weld nugget so formed is thinner and of a larger transverse cross-sectional area than would be produced without application of the follow up force. | 07-17-2014 |
| 20140200409 | ACCESS DEVICE FOR ACCESSING TISSUE - A clip is provided for managing access through tissue. The clip is placed around an opening in tissue, although the opening may alternatively be formed after the clip is deployed. The clip can expand when medical devices are introduced through the clip and through the opening. When the medical devices are removed, the clip closed automatically to substantially close the opening. | 07-17-2014 |
| 20140199377 | MULTIPLE GROWTH FACTOR COMPOSITIONS, METHODS OF FABRICATION, AND METHODS OF TREATMENT - Disclosed are compositions with sustained-release carriers associated with at least two different types of growth factors and methods of fabrication and treatments thereof. In some embodiments, simultaneous release of the growth factors may be preferred while in other embodiments, sequential release of the growth factors may be preferred. Application of at least two growth factors to an injury site, e.g., compromised cardiac tissue caused by, for example, myocardial infarction or ischemic heart failure, may better mimic and induce the complex growth factor signaling pathways necessary to improve cardiac function. When applied to a patient after a myocardial infarction or ischemic heart failure, multiple growth factors within a sustained-release carrier platform or platforms may cause a synergistic effect on injected cells intending to alleviate left ventricle remodeling. Methods of treatment include percutaneous, sub-xiphoid, and open chest methods using catheters and/or syringes. | 07-17-2014 |
| 20140193569 | STENT WITH PREFERENTIAL COATING - This invention relates to stents, a type of implantable medical device, with an antiproliferative coating and a prohealing luminal coating and methods of fabricating stents with an antiproliferative coating and a prohealing luminal coating. | 07-10-2014 |
| 20140193475 | POLYMERS COMPRISING AMORPHOUS TERPOLYMERS AND SEMICRYSTALLINE BLOCKS - The present invention provides an implantable article comprising an amorphous terpolymer and a semi-crystalline polymer. The amorphous terpolymer can be admixed with the semi-crystalline polymer or form a block copolymer with the semi-crystalline polymer. | 07-10-2014 |
| 20140190630 | Method for Forming Catheter Balloon - Method of making a balloon catheter includes providing an elongated shaft having a proximal end and a distal end and an inflation lumen extending therein, providing a multilayer tube, forming a multilayer balloon by blow-molding the multilayer tube such that the multilayer balloon is blown, in at least a first stage, to a final working radial dimension, and securing the multilayer balloon on a distal section of the shaft with an interior of the multilayer balloon in fluid communication with the inflation lumen. The ADDR of the multilayer balloon after formation is approximately 2.0. | 07-10-2014 |
| 20140190230 | NICKEL-TITANIUM CORE GUIDE WIRE - A guide wire for use in a medical procedure having a shapeable tip integral with and made from the distal end of a superelastic nitinol distal section of the guide wire, wherein the shapeable tip can be finger kinked. Such a guide wire includes an elongated core made from a superelastic nitinol alloy at the distal end, the distal end of the elongated core having a tapered section leading to a shapeable distal tip. The shapeable tip is an extension of the distal end of the nitinol distal section, and includes permanent strain hardening from at least two different radial directions imparting crystallographic texture in the radial directions that eliminate superelasticity so that permanent deformation can be achieved with finger pressure. | 07-10-2014 |
| 20140189994 | Post-Crimping Inspection of Scaffolds Mounted on Scaffold Delivery Systems - A system for mounting a scaffold on a balloon catheter includes two positioning and alignment stations, which are used to prepare a scaffold and catheter for crimping using the same crimping head. The system is configured for automated assembly of the scaffold and catheter prior to crimping and performing post-crimping inspection for the crimped scaffold and prior to placing a restraining sheath over the crimped scaffold. | 07-10-2014 |
| 20140188035 | METHODS AND DEVICES FOR IN VIVO TARGETED LIGHT THERAPY - Catheter-based systems for in-vivo targeted light therapy include a first type of catheter configured for photo-activating photosensitive substances in tissue, and a second type of catheter configured for photo-degrading photosensitive substances in tissue. The catheters may be configured to produce light using a variety of light sources, such as light emitting diodes (LEDs) and fiber optics. The light transmission is directed to tissue in such a way that only portions of tissue in a treatment area are exposed to light, depending upon whether the tissue is diseased or healthy. | 07-03-2014 |
| 20140186417 | Tailored Aliphatic Polyesters for Stent Coatings - An aliphatic polyester polymer for stent coating is described. | 07-03-2014 |
| 20140180396 | HINGE FOR MEDICAL DEVICE - A device is provided that provides flexibility to an assembly. The device includes a loop hinge that hinges by twisting a body of the loop hinge. | 06-26-2014 |
| 20140180311 | ARTICULATING SUTURING DEVICE - An apparatus for closing an opening in a body tissue. The apparatus includes a shaft, a plurality of arms, and an expander. The arms each extend between a proximal end and a distal end. The distal end of each arm is hingedly attached to or integrally formed with the shaft. The arms are laterally spaced apart from each other. The arms are movable between a retracted configuration, in which the arms are each aligned along the shaft, and a deployed configuration, in which the proximal end of each arm pivots respectively about the distal end of the arm so as to extend laterally away from the shaft. The expander is positioned within the shaft, and movement of the expander causes the arms to move between the retracted and deployed configurations. Methods of using the apparatus are also included. | 06-26-2014 |
| 20140178452 | Anti-Proliferative and Anti-Inflammatory Agent Combination for Treatment of Vascular Disorders with an Implantable Medical Device - Drug-delivery systems such as drug-delivery stents having an anti-proliferative agent such as everolimus and an anti-flammatory agent such as clobetasol are provided. Also disclosed are methods of treating a vascular impairment such as restenosis or vulnerable plaque. | 06-26-2014 |
| 20140172063 | DRUG-ELUTING STENT AND DELIVERY SYSTEM WITH TAPERED STENT IN SHOULDER REGION - A drug-eluting stent delivery system for the treatment of edge restenosis in a blood vessel. The drug-eluting stent delivery system has a balloon disposed about at least a portion of a catheter, the balloon having a first end and a second end and a working length therebetween, the first end and the second end each including a tapered portion, each tapered portion being attached to the catheter, the balloon being inflatable from a collapsed configuration to an inflated configuration. A drug-eluting stent contacts a wall of the blood vessel to maintain the patency of the vessel. The drug-eluting stent has a first end and a second end, the first end and the second end each including a tapered portion, wherein the drug-eluting stent is disposed over the balloon such that at least a portion of the first end and the second end of the balloon are covered by the tapered drug-eluting stent. A method for making the same is also disclosed herein. | 06-19-2014 |
| 20140163666 | INTRAVASCULAR STENT - An expandable stent for implantation in a body lumen, such as an artery, is disclosed. The stent consists of a plurality of radially expandable cylindrical rings generally aligned on a common longitudinal stent axis and interconnected by one or more interconnecting links placed so that the stent is flexible in the longitudinal direction. The link pattern is optimized to reduce strain on the links and enhance longitudinal flexibility and security of the stent. The stent includes a distal end ring and a proximal end ring that have a length that is shorter than the length of the body rings. | 06-12-2014 |
| 20140163601 | E-SPUN MEDICAL BALLOON HAVING VARIED THICKNESS AND METHODS FOR FORMING SAME - The disclosed subject matter describes systems and methods of electrospinning a fiber for a variety of applications. An exemplary embodiment includes a medical device application for delivering a therapeutic agent, such as a sclerosing agent, to the walls of a blood vessel to perform sclerotherapy. A method of fabricating a medical balloon comprises charging a polymer material with an electric voltage, dispensing the charged polymeric material through a nozzle, collecting the charged polymeric material on a grounded mandrel, wherein the mandrel includes a tubular body having a plurality of openings extending through the tubular body, and forming an electrospun medical balloon defined by a body having a varied thickness. | 06-12-2014 |
| 20140163525 | Balloon With Fibers for Treatment of Blood Vessels - The disclosed subject matter describes systems and methods of delivering a therapeutic agent, such as a sclerosing agent, to the walls of a blood vessel to perform sclerotherapy. In an exemplary embodiment a catheter includes a balloon having an inner and outer surface defining a wall, and an interior volume with an unexpanded and expanded configuration and a plurality of fibers extending from the outer surface of the balloon wall. In another exemplary embodiment, a balloon catheter comprises a catheter having a balloon with an unexpanded and an expanded configuration, and a retractable sheath disposed on the exterior surface of the balloon, wherein the sheath has an inner surface and an outer surface, and further wherein a plurality of fibers outwardly extend from the outer surface of the sheath. | 06-12-2014 |
| 20140163466 | CATHETER HAVING TRANSITIONING SHAFT SEGMENTS - Balloon catheter includes an elongate tubular shaft having an outer tubular member having proximal and distal portions, and an inner tubular member having a distal length extending distally from the distal portion of the outer tubular member. The elongate tubular shaft has an inflation lumen and a guidewire lumen defined therein. The guidewire lumen extends along at least the distal length of inner tubular member. The balloon catheter also includes a distal end section coupled to a distal end of the inner tubular member and having a proximal end and a distal end. The balloon catheter also includes a balloon having a proximal portion sealingly coupled to the distal portion of the outer tubular member, a distal portion sealingly coupled to the distal end section, and a working length therebetween. The balloon defines an inner chamber. The proximal end of the distal end section is disposed within the inner chamber. | 06-12-2014 |
| 20140161862 | ABSORBABLE COATING FOR IMPLANTABLE DEVICE - The present invention provides an absorbable coating for an implantable device and the methods of making and using the same. | 06-12-2014 |
| 20140157567 | Sheaths Reducing Recoil and Loss of Retention for Polymer Scaffolds Crimped to Balloons - A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. A single piece sheath is placed over the scaffold immediately following crimping of the scaffold to the balloon. The single piece sheath is replaced by a two-piece sheath, which is removed prior to performing a medical procedure using the medical device. | 06-12-2014 |
| 20140155986 | INTRAVASCULAR STENT - The invention is directed to an expandable stent for implanting in a body lumen, such as a coronary artery, peripheral artery, or other body lumen. The invention provides for a an intravascular stent having a plurality of cylindrical rings connected by undulating links. The stent has a high degree of flexibility in the longitudinal direction, yet has adequate vessel wall coverage and radial strength sufficient to hold open an artery or other body lumen. | 06-05-2014 |
| 20140155824 | Drug Delivery Medical Devices - Medical devices for delivering a bioactive agent and methods of use thereof are provided. The device includes a balloon having micro-needles for delivery of the bioactive agent. | 06-05-2014 |
| 20140155823 | CATHETER WITH A DUAL LUMEN MONOLITHIC SHAFT - Multi-lumen catheter having a monolithic elongate tubular shaft member having a proximal end, a distal end and a longitudinal length therebetween. The tubular shaft member has an outer cross-sectional dimension that varies along the length of the tubular shaft member. The tubular shaft member has an inner core made of a first material and an outer layer made of a second material. The inner core has a first lumen and a second lumen defined therein, the first lumen having a first lumen cross-section and a length extending at least along a portion of the length of the tubular shaft member. The first lumen cross-section is substantially uniform along the length of the first lumen. The second lumen has a second lumen cross-section and a length extending along the length of tubular shaft member. The second lumen cross-section is substantially uniform along the length of the second lumen. | 06-05-2014 |
| 20140155684 | METHOD FOR INCREASED UPTAKE OF BENEFICIAL AGENT AND EJECTION FRACTION BY POSTCONDITIONING PROCEDURES - A method for improving tissue uptake of beneficial agent and ejection fraction. | 06-05-2014 |
| 20140154400 | METHOD OF DRYING BIOABSORBABLE COATING OVER STENTS - Various embodiments of methods for coating stents are described herein. Applying a composition including polymer component and solvent to a stent substrate followed by exposing the polymer component to a temperature equal to or greater than a Tg of the polymer component is disclosed. Repeating the applying and exposing one or more times to form a coating with the result that the solvent content of the coating after the final exposing step is at a level suitable for a finished stent is further disclosed. | 06-05-2014 |
| 20140154300 | METHODS AND COMPOSITIONS FOR TREATMENT OF LESIONED SITES OF BODY VESSELS - Methods and compositions for inducing apoptosis of cells, such as macrophages, at a lesioned site of a body vessel are disclosed herein. Nitric oxide can be directly or indirectly delivered to a treatment site to increase macrophage apoptosis. Delivery can include site specific delivery of nitric oxide gas, nitric oxide in aqueous solution or a substance(s) which releases nitric oxide or causes nitric oxide to be generated from an endogenous source. Delivery can be achieved by a delivery system such as a catheter assembly, stent or other suitable device. | 06-05-2014 |
| 20140150282 | Device for Drying Coated Stents - Various embodiments of methods and devices for drying coated stents in an oven are described herein. | 06-05-2014 |
| 20140147687 | BIOLOGICALLY ABSORBABLE COATING FOR IMPLANTABLE DEVICES BASED ON COPOLYMERS HAVING ESTER BONDS AND METHODS OF FABRICATING THE SAME - Coatings for an implantable medical device and a method of fabricating thereof are disclosed, and the coatings comprise biologically absorbable poly(ester amides). | 05-29-2014 |
| 20140147686 | BIOLOGICALLY ABSORBABLE COATING FOR IMPLANTABLE DEVICES BASED ON COPOLYMERS HAVING ESTER BONDS AND METHODS OF FABRICATING THE SAME - Coatings for an implantable medical device and a method of fabricating thereof are disclosed, and the coatings comprise biologically absorbable poly(ester amides). | 05-29-2014 |
| 20140147485 | POLYMER FOR CREATING HEMOCOMPATIBLE SURFACE - A polymer comprising a phosphoryl choline moiety(ies), a composition comprising the polymer and optionally a bioactive agent, an implantable device such as a DES or a non-implantable device such as an angioplasty balloon comprising thereon a coating comprising the polymer and optionally a bioactive agent, and a method of using the device for the treatment of a disorder in a human being are provided. | 05-29-2014 |
| 20140142505 | MULTILAYER BALLOON FOR A CATHETER - Multilayer balloon for a catheter comprises a first layer made of a first polymer material having a first Shore durometer hardness, a second layer made of a second polymer material having a second Shore durometer hardness greater than the first Shore durometer hardness, wherein the second layer is an inner layer relative to the first layer, and a third layer made of a third polymer material having a third Shore durometer hardness less the first Shore durometer hardness, wherein the third layer is an inner layer relative to the second layer. Method of making a multilayer balloon for a catheter and a balloon catheter are also provided. | 05-22-2014 |
| 20140135685 | STEERABLE ASSEMBLY FOR SURGICAL CATHETER - A catheter configured for intraluminal delivery to a location in the body of a patient, the catheter comprising a steerable assembly comprising a first segment connected to a second segment; the first segment comprises first and second cylindrical elements connected to each other by a first revolute joint in a first single plane; the second segment comprises third and fourth cylindrical elements connected to each other by a second revolute joint in a second single plane, wherein the first single plane and the second single plane are offset by an angle from each other. | 05-15-2014 |
| 20140134323 | METHODS OF MANUFACTURE OF BIORESORBABLE AND DURABLE STENTS WITH GROOVED LUMENAL SURFACES FOR ENHANCED RE-ENDOTHELIALIZATION - Methods of making bioabsorbable stents with grooved lumenal surfaces for enhanced re-endothelialization are disclosed. Methods include molding grooves on the lumenal surface of coated bioresorbable and durable stents. Methods further include molding grooves on lumenal surfaces of a bioresorbable tube and forming a scaffold from the tube. | 05-15-2014 |
| 20140128959 | Biodegradable stent with enhanced fracture toughness - Stents and methods of manufacturing a stents with enhanced fracture toughness are disclosed. | 05-08-2014 |
| 20140127279 | Implantable Device Having a Slow Dissolving Polymer - The present invention provides an implantable device having a coating including a slow dissolving polymer or material and the methods of making and using the same. | 05-08-2014 |
| 20140127278 | Method Of Treating Vascular Disease In Diabetic Patients - The present invention relates to the treatment of vascular disease in a diabetic patient using a drug-eluting implantable medical device that releases everolimus from three distinctly loaded drug reservoir layers wherein at least one of the layers comprises at least 200 μg/cm | 05-08-2014 |
| 20140123602 | Sterilization Methods for Medical Devices - Methods of sterilizing medical devices, including implantable medical devices like stents, chemically and with radiation are disclosed. Methods of preparing a sterile, packaged medical device, including a sterile, packaged implantable medical device or stent are disclosed. | 05-08-2014 |
| 20140123463 | CATHETER WITH RADIOPAQUE COIL - A balloon catheter having a radiopaque coil embedded in the catheter's body corresponding to a landmark of the balloon or other location on the catheter body. The radiopaque coil can be viewed under fluoroscopy to located the balloon or other structure of the catheter. The coil can be readily inserted in the manufacturing process by inserting it between two layers that form the catheter body, and then sealing the coil inside the catheter at the desired location. This facilitates both the manufacturing process and prevents the marker from being dislodged during the manufacturing, navigation, or inflation process. | 05-08-2014 |
| 20140121603 | AGENT DELIVERY CATHETER HAVING RADIALLY EXPANDABLE CENTERING SUPPORT MEMBER - A catheter for delivering an agent to an injection site in a wall of a patient's body lumen, with an elongated shaft having a needle-through lumen slidably containing a needle therein, and an expandable member on the distal shaft section which has a collapsed configuration and a radially expanded configuration. In the radially expanded configuration, the expandable member supports the shaft in a position spaced away from the body lumen wall, and the needle slidably exits the needle-through lumen in the extended configuration through the port spaced away from the body lumen wall as a portion of the expandable member maintains the position of the port section of the shaft in the body lumen. The expandable member typically has an open-walled, helical, or lobed configuration providing a perfusion path along the expandable member. | 05-01-2014 |
| 20140121294 | METHODS FOR FABRICATING POLYMER-BIOCERAMIC COMPOSITE IMPLANTABLE MEDICAL DEVICES - Methods relating to polymer-bioceramic composite implantable medical devices are disclosed. | 05-01-2014 |
| 20140120053 | POLYESTERAMIDE PLATFORM FOR SITE SPECIFIC DRUG DELIVERY - A therapeutic agent delivery system formed of a specific type of poly(ester amide) (PEA), a therapeutic agent, and a water miscible solvent is described herein. A method of delivering the therapeutic agent delivery system by delivering the therapeutic agent delivery system formed of a PEA polymer, a therapeutic agent, and a water miscible solvent to a physiological environment and separating the phase of the therapeutic agent delivery system to form a membrane from the polymer to contain the therapeutic agent within the physiological environment is also described. Additionally disclosed is a kit including a syringe and a therapeutic agent delivery system within the syringe. | 05-01-2014 |
| 20140114401 | Method Of Reducing MACE In Diabetic Patients Subsequent To Stent Placement - This invention relates to the use of dual variable domain antibodies to locate naturally-occurring beneficial agents or therapeutic agents at a region of stent implantation in diabetic patients who have undergone stent implantation. | 04-24-2014 |
| 20140114399 | METHODS FOR VASCULAR RESTORATION THERAPY - A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. The scaffold has a structure that produces a low late lumen loss when implanted within a peripheral vessel and also exhibits a high axial fatigue life. In a preferred embodiment the scaffold forms ring structures interconnected by links, where a ring has 12 crowns and at most two links connecting adjacent rings. | 04-24-2014 |
| 20140114398 | TIME-DEPENDENT POLYMER SCAFFOLDS - A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. The scaffold has a structure that produces a low late lumen loss when implanted within a peripheral vessel and also exhibits a high axial fatigue life. In a preferred embodiment the scaffold forms ring structures interconnected by links, where a ring has 12 crowns and at most two links connecting adjacent rings. | 04-24-2014 |
| 20140114394 | Biodegradable stent with enhanced fracture toughness - Stents and methods of manufacturing a stents with enhanced fracture toughness are disclosed. | 04-24-2014 |
| 20140113059 | MAINTAINING A FIXED DISTANCE BY PROVIDING AN AIR CUSHION DURING COATING OF A MEDICAL DEVICE - System and method for coating an expandable member of a medical device comprising a support structure to support the expandable member and an applicator positioned with at least one outlet proximate a surface of an expandable member. A drive assembly establishes relative movement between the at least one outlet and the surface of the expandable member to apply fluid on the surface of the expandable member along a coating path. A positioning device maintains a substantially fixed distance between the at least one outlet and the surface of the expandable member during relative movement therebetween by ejecting a pressurized medium against the surface of the expandable member. | 04-24-2014 |
| 20140110885 | POST ELECTRON BEAM CONDITIONING OF POLYMERIC MEDICAL DEVICES - Methods are disclosed for conditioning a polymeric stent after sterilization, and/or after crimping and before packaging, such that the properties of the polymeric stent fall within a narrower range of values. The stent is exposed to a controlled temperature at or above ambient for a period of time after radiation sterilization and/or after crimping and before sterilization. As a result, the polymeric stent properties, particularly radial strength and number-average molecular weight of the polymer of the polymeric stent, fall within a narrower range. | 04-24-2014 |
| 20140107762 | Biodegradable stent with enhanced fracture toughness - Stents and methods of manufacturing a stents with enhanced fracture toughness are disclosed. | 04-17-2014 |
| 20140107761 | Biodegradable stent with enhanced fracture toughness - Stents and methods of manufacturing a stents with enhanced fracture toughness are disclosed. | 04-17-2014 |
| 20140107759 | STENT LOCKING ELEMENT AND A METHOD OF SECURING A STENT ON A DELIVERY SYSTEM - A stent with a stent locking element and a method of securing a stent on a delivery implement, such as a catheter are disclosed. The locking element can include coupling elements capable of being releasably coupled to one another. The coupling elements may be adapted to inhibit shifting of the stent on the delivery implement. In some embodiments, the releasably coupled elements may secure the stent on the delivery implement. | 04-17-2014 |
| 20140107592 | COATING COMPRISING A TERPOLYMER COMPRISING CAPROLACTONE AND GLYCOLIDE - The present invention provides a coating comprising a reservoir layer comprising a terpolymer comprising caprolactone and glycolide and a primer layer comprising an amorphous polymer on an implantable device and methods of making and using the same. | 04-17-2014 |
| 20140102049 | Method Of Fabrication Of Implantable Medical Device Comprising Macrocyclic Triene Active Agent And Antioxidant - This invention relates to methods of including an oxygen-sensitive macrocyclic triene on an implantable medical device wherein the device includes separate antioxidant-containing layers above, below or both above and below the drug reservoir layer containing the macrocyclic triene. | 04-17-2014 |
| 20140100649 | METHOD OF FABRICATING A LOW CRYSTALLINITY POLY(L-LACTIDE) TUBE - Methods of fabricating a low crystallinity polymer tube for polymers subject to strain-induced crystallization. The low crystallinity tube may be further processed to make an implantable medical device. | 04-10-2014 |
| 20140100447 | POLYMERIC MARKER WITH HIGH RADIOPACITY FOR USE IN MEDICAL DEVICES - High radiopacity is achieved in a polymeric marker by combining a polymeric resin, a powdered radiopaque agent having uniformly shaped particles of a specific particle size distribution and a wetting agent. The method to produce the marker calls for the blending and pelletization of these materials followed by extrusion onto support beading. The resulting supported tubing is subsequently cut to length with the beading still in place. After ejection of the beading remnant the marker is slipped into place on the device to be marked and attached by melt bonding. Marking of a guidewire allows lesions to be measured while the marking of balloon catheters allow the balloon to be properly positioned relative to a lesion. | 04-10-2014 |
| 20140100302 | COATINGS FOR IMPLANTABLE DEVICES COMPRISING POLY(HYDROXY-ALKANOATES) AND DIACID LINKAGES - Coatings for an implantable medical device and a method of fabricating thereof are disclosed, the coatings including block-polymers comprising at least one poly(hydroxyacid) or poly(hydroxy-alkanoate) block, at least one block of a biologically compatible polymer and at least one type of linking moiety. | 04-10-2014 |
| 20140096357 | Method of Uniform Crimping and Expansion of Medical Devices - A medical device-includes a scaffold crimped to a catheter having an expansion balloon. The scaffold is crimped to the balloon by a process that includes one or more balloon pressurization steps. The balloon pressurization steps are selected to enhance scaffold retention to the balloon, maintain a relatively uniform arrangement of balloon folds about the inner surface of the crimped scaffold so that the scaffold expands in a uniform manner when the balloon is inflated, and to avoid any possible over-stretching of balloon material. | 04-10-2014 |
| 20140094899 | METHODS OF FABRICATING STENTS WITH ENHANCED FRACTURE TOUGHNESS - Stents and methods of manufacturing a stents with enhanced fracture toughness are disclosed. | 04-03-2014 |
| 20140090231 | Crush Recoverable Polymer Scaffolds - A method of manufacturing a stent is disclosed. The stent includes a minimum crimped diameter such that in the minimum crimped diameter, a pair of stent rings, between which marker support structures reside, do not make contact with the marker support structures. The crimped profile of the stent of the present invention can be as small as the crimped profile of a same stent but without the marker support structures. | 04-03-2014 |
| 20140084515 | IMPLANTABLE MEDICAL DEVICE MADE FROM AN AMORPHOUS OR VERY LOW CRYSTALLINITY POLYMER CONSTRUCT - Methods of fabricating a polymeric implantable device with improved fracture toughness through annealing, nucleating agents, or both are disclosed herein. A polymeric construct that is completely amorphous or that has a very low crystallinity is annealed with no or substantially no crystal growth to increase nucleation density. Alternatively, the polymer construct includes nucleating agent. The crystallinity of the polymer construct is increased with a high nucleation density through an increase in temperature, deformation, or both. An implantable medical device, such as a stent, can be fabricated from the polymer construct after the increase in crystallinity. | 03-27-2014 |
| 20140081417 | IMPLANTABLE MEDICAL DEVICES FABRICATED FROM BRANCHED POLYMERS - Stent scaffolds comprising branched biocompatible polymers are disclosed. | 03-20-2014 |
| 20140081379 | METHODS OF FABRICATING STENTS WITH ENHANCED FRACTURE TOUGHNESS - Stents and methods of manufacturing a stents with enhanced fracture toughness are disclosed. | 03-20-2014 |
| 20140081378 | METHODS OF FABRICATING STENTS WITH ENHANCED FRACTURE TOUGHNESS - Stents and methods of manufacturing a stents with enhanced fracture toughness are disclosed. | 03-20-2014 |
| 20140081377 | STENT WITH RETENTION PROTRUSIONS FORMED DURING CRIMPING - Stents that forms protrusions in a crimped state and methods of crimping the stent are disclosed. | 03-20-2014 |
| 20140081373 | STENT WITH RETENTION PROTRUSIONS FORMED DURING CRIMPING - Stents that forms protrusions in a crimped state and methods of crimping the stent are disclosed. | 03-20-2014 |
| 20140081372 | STENT WITH RETENTION PROTRUSIONS FORMED DURING CRIMPING - Stents that forms protrusions in a crimped state and methods of crimping the stent are disclosed. | 03-20-2014 |
| 20140081310 | ROBUST MULTI-LAYER BALLOON - A multilayer balloon catheter is formed to have an inner layer and an outer layer, where the outer layer is adapted to resist shredding and premature rupture. The outer layer is formed of a material having a glass transition temperature that is lower than the transition or melting temperature of the inner layer. By forming the balloon on a mold at a temperature between the glass transition temperature of the outer layer and the glass transition or melting temperature of the inner layer, the outer layer will undergo a thermal relaxation that will alleviate some of the axial orientation of the polymer chains that develop during the formation of the multilayer balloon. This relaxation leads to a resistance to shredding when the balloon is expanded during operation. | 03-20-2014 |
| 20140079743 | COATINGS OF ACRYLAMIDE-BASED COPOLYMERS - An implantable device including a conjugate formed of an acrylamide-based copolymer and a bioactive agent is provided. | 03-20-2014 |
| 20140079742 | COATING OF FAST ABSORPTION OR DISSOLUTION - A coating of fast absorption or fast dissolution on an implantable device and methods of making and using of the coating are provided. | 03-20-2014 |
| 20140076739 | ELECTROPOLISHING DEVICE AND METHOD - A device for repositioning a device during an electropolishing process. A fixture is disclosed that is configured to reposition the device during the electropolishing process in order to more evenly electropolish a surface of the device. | 03-20-2014 |
| 20140076737 | ELECTROPOLISHING FIXTURE WITH PLUNGER MECHANISM - An electropolishing fixture with a plunger mechanism. The plunger mechanism can establish contact between a device and an anode mandrel during an electropolishing process while the device is immersed in an electrolytic bath. | 03-20-2014 |
| 20140076720 | ELECTROPOLISHING FIXTURE WITH LEVER ARM - An electropolishing system that includes electropolishing fixtures. The electropolishing fixtures include pendulum assemblies configured to establish electrical contact between a device being electropolished and an anode and to reposition the device during the electropolishing process. | 03-20-2014 |
| 20140076719 | ELECTROPOLISHING METHOD INCLUDING MULTI-FINGER CONTACTS - Systems and methods for electropolishing devices are disclosed. The electropolishing system includes electropolishing fixtures configured to reposition the devices during the electropolishing process. | 03-20-2014 |
| 20140075735 | Crush Recoverable Polymer Scaffolds - A method of crimping a stent is disclosed. The stent includes a minimum crimped diameter such that in the minimum crimped diameter, a pair of stent rings, between which marker support structures reside, do not make contact with the marker support structures. The crimped profile of the stent of the present invention can be as small as the crimped profile of a same stent but without the maker support structures. | 03-20-2014 |
| 20140074224 | COATING OF FAST ABSORPTION OR DISSOLUTION - A coating of fast absorption or fast dissolution on an implantable device and methods of making and using of the coating are provided. | 03-13-2014 |
| 20140074216 | STENT WITH RETENTION PROTRUSIONS FORMED DURING CRIMPING - Stents that forms protrusions in a crimped state and methods of crimping the stent are disclosed. | 03-13-2014 |
| 20140074126 | REMOVING NEEDLES FROM A SUTURING DEVICE - Suturing systems and needle removal devices for more efficiently removing needles from suturing systems are provide. In some embodiments, a suturing system guide body includes one or more needle lumens that transfer corresponding needles circumferentially around the guide body. Thus, when the needles exit the needle lumens at the proximal end of the guide body, the needles are in closer proximity to one another for removal. Other embodiments include various needle capture devices tools used for removing needles from a suturing system. Needle capture devices and tools can include needle receptacles positioned and configured to generally correspond to the needle lumens of the suturing system. The needle receptacles may be further configured to selectively receive and grasp onto one or more needles extending proximally from the needle lumens of the suturing system. | 03-13-2014 |
| 20140074124 | NEEDLE HARVESTING DEVICES, SYSTEMS AND METHODS - A needle removal device is provided for removing needles from suturing devices and/or systems. In an embodiment, the needle removal device may be intended for use with a suturing device having one or more needle lumens. The needle removal device may include a first member having a first plurality of needle receptacles extending therethrough. The first needle receptacles may be configured and positioned to correspond to one or more of the one or more needle lumens of the suturing device. The needle removal device may also include a second member having a second plurality of needle receptacles extending therethrough. At least one of the first member or the second member may be moveable between a first position, wherein the first needle receptacles and the second needle receptacles are substantially aligned, and a second position, wherein the first needle receptacles and the second needle receptacles substantially unaligned. | 03-13-2014 |
| 20140074123 | NEEDLE REMOVAL DEVICES, SYSTEMS, AND METHODS - A needle removal device is provided for removing needles from suturing systems. In an embodiment, the needle removal device may include a base member configured to be selectively positioned substantially adjacent a proximal portion of a suturing system. The proximal portion of the suturing system may include a plurality of needle lumens. The needle removal device may also include a plurality of needle receptacles at least partially defined by the base member. The needle receptacles may be positioned and configured to generally correspond to the needle lumens of the suturing system. The needle receptacles may be further configured to selectively receive and grasp onto one or more needles extending proximally from the needle lumens of the suturing system. | 03-13-2014 |
| 20140072695 | DIRECT FLUID COATING OF DRUG ELUTING BALLOON - A system and method for coating an expandable member of a medical device comprises providing a dispenser in fluid communication with a fluid source with the dispenser having at least one outlet to dispense fluid of the fluid source therefrom. The outlet(s) of the dispenser is positioned proximate a surface of an expandable member, with relative movement between the outlet(s) and the surface of the expandable member established along a coating path, and fluid is dispensed from the dispenser to form a substantially continuous bead of fluid between the at least one outlet and the surface of the expandable member along the coating path, and simultaneously drying the fluid while dispensing the fluid from the dispenser to control flow of fluid on the surface of the expandable member. The fluid source can include a variety of therapeutic agents. | 03-13-2014 |
| 20140072609 | BIODEGRADABLE TRIBLOCK COPOLYMERS FOR IMPLANTABLE DEVICES - The present invention is directed to polymeric materials made of biodegradable, bioabsorbable triblock copolymers and implantable devices (e.g., drug-delivery stents) containing such polymeric materials. The polymeric materials may also contain at least one therapeutic substance. The polymeric materials are formulated so as to improve the mechanical and adhesion properties, degradation, biocompatibility and drug permeability of such materials and, thus, implantable devices formed of such materials. | 03-13-2014 |
| 20140067044 | Crush Recoverable Polymer Scaffolds - A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. The scaffold, after being deployed by the balloon, provides a crush recovery of about 90% after the diameter of the scaffold has been pinched or crushed by 50%. The scaffold has a pattern including an asymmetric closed cell connecting links connecting the closed cells. | 03-06-2014 |
| 20140065093 | Compositions For Achieving A Therapeutic Effect In An Anatomical Structure - Compositions and methods of using the compositions are provided for forming an embolus within a region of an anatomical lumen for a transitory period in order to achieve a therapeutic effect. | 03-06-2014 |
| 20140065012 | METHOD FOR RADIATION STERILIZATION OF MEDICAL DEVICES - Methods and systems for selection radiation exposure in sterilization of medical devices are disclosed. | 03-06-2014 |
| 20140058499 | Crush Recoverable Polymer Scaffolds - A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. The scaffold, after being deployed by the balloon, provides a crush recovery of about 90% after the diameter of the scaffold has been pinched or crushed by 50%. The scaffold has a pattern including an asymmetric closed cell connecting links connecting the closed cells. | 02-27-2014 |
| 20140057042 | Method for Coating and Drying Multiple Stents - A coating and drying apparatus for the application of a coating substance to a stent and drying the stent is provided. | 02-27-2014 |
| 20140052235 | STENT RETAINED ON A BALLOON CATHETER - A balloon is inflated from a collapsed configuration, then deflated. A polymeric stem is then disposed over the deflated balloon and the stent crimped to the balloon. | 02-20-2014 |
| 20140052052 | NEEDLE CATHETER FOR DELIVERY OF AGENTS DIRECTLY INTO VESSEL WALL - A system and method for treating a patient including advancing a catheter into the vasculature of the patient, forcing the catheter to adopt a position in contact with a vessel wall, and causing a needle tip to advance into the wall from a lumen in the catheter external surface that is in contact with the wall. | 02-20-2014 |
| 20140046431 | SEGMENTED SCAFFOLD DESIGNS - Segmented scaffolds composed of disconnected scaffold segments with overlapping end rings are disclosed. Scaffolds with at least one discontinuous link are also disclosed. | 02-13-2014 |
| 20140046300 | LOW PROFILE AGENT DELIVERY PERFUSION CATHETER HAVING A FUNNEL-SHAPED MEMBRANE - An agent delivery catheter and method configured to deliver an agent to an inner surface of a patient's body lumen wall by forming a funnel shaped agent containment chamber around at least one portion of the inner surface of the body lumen wall, while minimizing ischemic conditions during the procedure. | 02-13-2014 |
| 20140046254 | DRUG COATED BALLOON CATHETER AND PHARMACOKINETIC PROFILE - A drug delivery balloon is provided comprising a balloon having a surface, and a coating disposed on at least a portion of the balloon surface, the coating including an cytostatic therapeutic agent, an excipient, and a plasticizer. In accordance with the present subject matter, at least 30% of the coating transfers from the balloon surface within two minutes after inflation of the balloon. Alternatively, at least 30% of the coating transfers from the balloon surface within one minute after inflation. The coating results in an effective pharmacokinetic profile of an cytostatic therapeutic agent in a vasculature or target tissue. | 02-13-2014 |
| 20140046253 | Methods and Devices for Eluting Agents to a Vessel - Systems, devices and methods for eluting an agent at a treatment site are disclosed. The devices include an expandable frame and at least one membrane. The membrane may carry an agent to elute at the treatment site. The membrane may allow blood flow at the treatment site during agent delivery. | 02-13-2014 |
| 20140046006 | IMPLANTABLE MEDICAL DEVICES FABRICATED FROM BRANCHED POLYMERS - Implantable medical devices fabricated from branched polymers are disclosed. | 02-13-2014 |
| 20140044860 | METHODS TO INCREASE FRACTURE RESISTANCE OF A DRUG-ELUTING MEDICAL DEVICE - Methods for increasing the fracture resistance of a polymer stent's drug-polymer coating and scaffolding including applying a coating and crimping using techniques that increase the resistance to fracture in the coating layer and scaffolding and scaffolding. | 02-13-2014 |
| 20140041580 | SYSTEM FOR COATING A STENT - A systems and method for reducing coating defects on a stent may involve a support apparatus comprising wire cage for carrying a stent. The support apparatus may have no structure that extends inside the stent. A support apparatus may include a plurality of wires that pass through the stent but do not pass through the midplane of the stent. A support apparatus may contact only the proximal ends of the stent. The method may involve keeping the stent in motion during a spray coating process to prevent the stent from having a point remain in continuous contact with a support apparatus. | 02-13-2014 |
| 20140039604 | CRUSH RECOVERABLE POLYMER SCAFFOLDS - A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. The scaffold, after being deployed by the balloon, provides a crush recovery of about 90% after the diameter of the scaffold has been pinched or crushed by 50%. The scaffold has a pattern including an asymmetric closed cell connecting links connecting the closed cells. | 02-06-2014 |
| 20140039603 | BIOABSORBABLE SCAFFOLDS MADE FROM COMPOSITES - Bioabsorbable scaffolds made at least in part of a poly(L-lactide)-based composite are disclosed. The composite includes poly(4-hydroxybutyrate) or poly(L-lactide)-b-polycaprolactone block copolymer, which increases the fracture toughness or fracture resistance of the scaffold. The composite can further include bioceramic particles, L-lactide monomer, or both dispersed throughout the composite. The bioceramic particles improve the radial strength and stiffness of the scaffold. The L-lactide monomer is used to control the absorption rate of the scaffold. | 02-06-2014 |
| 20140039271 | HINGED TISSUE SUPPORT DEVICE - A tissue support device is provided for managing access through tissue. The tissue support device engages the tissue proximate an opening in the tissue and biases the tissue support device to bring the engaged tissue together. | 02-06-2014 |
| 20140038907 | Coatings For Implantable Medical Devices - The present application teaches a coating having a biologically compatible compound conjugated to, or blended with, a polymer, wherein the polymer includes at least one olefin-derived unit and at least one unit derived from a vinyl alcohol, an allyl alcohol, or derivatives thereof. | 02-06-2014 |
| 20140037833 | METHOD FOR COATING A STENT - A systems and method for reducing coating defects on a stent may involve a support apparatus comprising wire cage for carrying a stent. The support apparatus may have no structure that extends inside the stent. A support apparatus may include a plurality of wires that pass through the stent but do not pass through the midplane of the stent. A support apparatus may contact only the proximal ends of the stent. The method may involve keeping the stent in motion during a spray coating process to prevent the stent from having a point remain in continuous contact with a support apparatus. | 02-06-2014 |
| 20140037832 | Coating Layers For Medical Devices And Method Of Making The Same - Methods are disclosed for controlling the morphology and the release-rate of active agent from coating layers for medical devices comprising a polymer matrix and one or more active agents. The methods comprise fixing the morphology or phase distribution of the active agent prior to removing solvent from the coating composition. The coating layers can be used for controlled the delivery of an active agent or a combination of active agents. | 02-06-2014 |
| 20140037831 | Coating Layers For Medical Devices And Method Of Making The Same - Methods are disclosed for controlling the morphology and the release-rate of active agent from coating layers for medical devices comprising a polymer matrix and one or more active agents. The methods comprise fixing the morphology or phase distribution of the active agent prior to removing solvent from the coating composition. The coating layers can be used for controlled the delivery of an active agent or a combination of active agents. | 02-06-2014 |
| 20140033506 | METHODS FOR CRIMPING A POLYMERIC STENT ONTO A DELIVERY BALLOON - A medical device—includes a polymer stent crimped to a catheter having an expansion balloon. The stent is crimped to the balloon by a process that includes heating the stent to a temperature below the polymer's glass transition temperature to improve stent retention without adversely affecting the mechanical characteristics of the stent when later deployed to support a body lumen. | 02-06-2014 |
| 20140033504 | Method of Making Implantable Prosthesis with Depot Retention Feature - A prosthesis for intraluminal drug delivery can comprise a plurality of interconnected struts that form a tubular scaffold structure. The struts include through-holes with an inner surface configured to retain a bioabsorbable depot. The bioabsorbable depot includes a drug-polymer composition that hydrolytically degrades upon implantation. The inner surface of the through-hole can be an entirely smooth and continuous area that is concave or convex, with no geometric discontinuities. The inner surface of the through-hole can include any number of constricted and distended regions to form grooves of a size and shape carefully selected to engage a corresponding geometric feature of the bioabsorbable depot. | 02-06-2014 |
| 20140031921 | CRUSH RECOVERABLE POLYMER SCAFFOLDS - A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. The scaffold, after being deployed by the balloon, provides a crush recovery of about 90% after the diameter of the scaffold has been pinched or crushed by 50%. The scaffold has a pattern including an asymmetric closed cell connecting links connecting the closed cells. | 01-30-2014 |
| 20140031919 | Drug Eluting Implantable Medical Device With Hemocompatible And/Or Prohealing Topcoat - The present invention relates to implantable medical devices coated with polymer having hemocompatible and/or prohealing moieties appended thereto and to their use in the treatment of vascular diseases. | 01-30-2014 |
