METHODS AND COMPOSITIONS FOR INHIBITING THE GROWTH AND/OR PROLIFERATION OF MYC-DRIVEN TUMOR CELLS

Abstract

The invention generally relates to methods for identifying and using anticancer therapeutic agents and, more particularly, to methods for identifying and using inhibitors of genes for inhibiting the growth and/or proliferation of MYC-driven tumor cells relative to normal cells.

Description

CROSS-REFERENCE TO RELATED APPLICATIONS

[0001] This application is continuation of U.S. patent application Ser. No. 14/237,838, filed Aug. 9, 2012, which is now issued U.S. Pat. No. 9,273,317, granted Mar. 1, 2016; which is a U.S. national phase of International Patent Application No. PCT/US2012/050186, filed Aug. 9, 2012; which claims benefit under 35 U.S.C. .sctn.119(e) of U.S. Provisional Application No. 61/521,715, filed on Aug. 9, 2011, which is incorporated by reference in its entirety.

STATEMENT REGARDING THE SEQUENCE LISTING

[0003] The Sequence Listing associated with this application is provided in text format in lieu of a paper copy, and is hereby incorporated by reference into the specification. The name of the text file containing the Sequence Listing is FHCR_014_02US_SEQ_LIST.txt. The text file is about 509 KB, was created on Jan. 19, 2016, and is being submitted electronically via EFS-Web.

FIELD OF THE INVENTION

[0004] The invention relates generally to methods for identifying and using anticancer therapeutic agents and, more particularly, to methods for identifying and using inhibitors of genes for inhibiting the growth and/or proliferation of MYC-driven tumor cells relative to normal cells.

BRIEF SUMMARY

[0005] Embodiments of the present invention include methods for inhibiting the growth and/or proliferation of a myc-driven cancer or tumor cell comprising the step of contacting the cancer or tumor cell with at least one inhibitor that inhibits the gene function of at least one of the genes listed in Table 1 or 2.

[0006] In certain embodiments, the myc-driven cancer cell is derived from one of the following: a neuroblastoma tumor, a metastatic neuroblastoma tumor, a medulloblastoma, a lymphoma, a rhabdomyosarcoma, a melanoma, a lung cancer, a liver cancer, a breast cancer, a colon cancer, a prostate cancer, an ovarian cancer, or Burkitt's lymphoma.

[0007] In particular embodiments, the tumor cell is contacted in vitro. In specific embodiments, the cancer cell is contacted in vivo in a mammalian subject, optionally a human patient diagnosed with a MYC-driven cancer, such as any of the aforementioned cancers/tumors.

[0008] In some embodiments, the inhibitor is a small molecule inhibitor that inhibits the function of the gene product. In certain embodiments, the inhibitor interferes with the transcription of mRNA from the gene. In particular embodiments, the inhibitor interferes with production/expression of functional gene product of the gene.

[0009] In certain embodiments, the gene is selected from the genes listed in Table 1. In specific embodiments, the gene is selected from the group consisting of ALDOA, CECR2, IGF2R, PAK6, PES1, RAD21, REV1L, SUV39H1, TIE1.

[0010] Also included are methods of treating a subject suffering from a tumor comprising myc-driven tumor cells, comprising administering to the subject an amount of a composition comprising an inhibitor that inhibits the gene function, transcription, production/expression, or activity of the gene product of at least one of the genes listed in Table 1 or 2, and is effective to inhibit the growth and/or proliferation of the tumor cells.

BRIEF DESCRIPTION OF THE DRAWINGS

[0011] FIGS. 1A-1G. Identification of synthetic lethal genes with c-MYC overexpression by high throughput siRNA screening. a, Graphical schematic of the siRNA screen. HFF expressing either c-MYC or transduced with an empty retroviral vector, pB, were plated in 384 well plates. 24 hr later they were transfected with siRNA pools (3 siRNAs/pool) targeting a total of .about.3,311 genes, with one gene targeted per well. At day 5, the viability was quantified utilizing an Alamar Blue staining assay and an EnVision plate reader. b, Graphical representation of cell viability as affected by each siRNA pool in both HFF-pB or HFF-c-MYC and quantified as % relative to mock (on a log 10 scale). Values represent the average viability of 3 replicates. A set of siRNAs (targeting 102 genes labeled as light shaded +) caused differential loss of viability (Z score>2) in the HFF-MYC versus control pB. An additional set of siRNAs targeting 20 genes caused selective growth advantage to HFF-MYC. c, CSNK1e, PES1 and CECR2 mRNA levels following lentiviral-mediated shRNA knock-down. Relative levels of each gene were calculated using the .DELTA..DELTA.CT method and using GAPDH to normalize mRNA levels within each sample. d, Viability of HFF-pBabe and HFF-Myc following stable, lentiviral based knock-down of MYC-SL genes CSNK1e, PES1 and CECR2. Values represent mean viability from 3 independent assays. e, -.gamma.-H2AX staining following transduction of HFF-pBabe and HFF-MYC with siRNAs pools corresponding to 40 MYC-SL genes and a previously identified MYC transcriptional target, DDX18. Representative images of anti-.gamma.-H2AX staining from the INCell automated scope (20.times. magnification) are shown. f, Graphical representation of the .gamma.-H2AX staining shown in (e). Y-axis indicates the % of cells stained with anti-.gamma.-H2AX that scored for nuclear fluorescence levels above a negative control established threshold. Quantitation was obtained by automated microscopy in 96 well format, from triplicate samples. g, Quantitative assessment of Caspase-3 and -7 cleavage following transfection of the same siRNA pools as above (measured by the CaspaseGlo kit, Promega). Horizontal dark bold line indicates the background levels in HFF c-Myc cells. Results were normalized for cell number by the Alamar Blue assay.

[0012] FIGS. 2A-D. The knockdown of CSNK1e in neuroblastoma cell lines impairs growth of neuroblastoma with MYCN amplification in vitro and in vivo. a, Relative levels of CSNK1e mRNA following doxycycline or DMSO treatment of neuroblastoma cells harboring shCSNK1e #1, #2 and sh control expressing lentivirus. Relative levels of each gene were calculated using the .DELTA..DELTA.CT method and using GAPDH to normalize mRNA levels within each sample. b, Viability assessment following growth under doxycycline containing medium for 4 days as measured by CellTiter Glo (Promega). Values represent mean viability normalized to mock treated cells. c, Representative western blot showing levels of CSNK1e protein in neuroblastoma cells transduced with doxycycline inducible shRNA lentivirus (two different sh: #1 and #2) targeting CSNK1e and non-target sequence (shControl) used in FIG. 2a. Cells were cultured in the presence or absence of doxycycline for 4 days. Actin is shown as a loading control. d, Xenograft tumor growth of SK-N-BE2 neuroblastoma cells transduced with doxycycline inducible shRNA for CSNK1e or shControl in NOD/SCID mice. Doxycycline exposure was started when tumors reached a size of about 100 mm.sup.3. Knockdown of CSNK1e inhibited growth of established xenograft in 3 out of 4 mice compared to no doxycycline treated control (arrows).

[0013] FIGS. 3A-3D. 1C261 treatment blocks MYCN amplified neuroblastoma tumor growth in vivo. a, Representative images of MYCN amplified neuroblastoma xenograft in NOD/SCID mice before and after treatment with either DMSO or IC261. Tumors were engrafted, and allowed to reach a size of about 100 mm.sup.3, then IC261 (21.5 mg/kg) or DMSO was injected subcutaneously daily for 8 days. b, Quantitation of tumor size over the 8-day treatment regimen with either IC261 or DMSO control. Values represent mean tumor volume at each time point (n=5 for each group, error bars indicate SD). c, Immunohistochemical analysis of tumor sections from IC261 and DMSO treatment groups described in a and b. Representative images of H-E, TUNEL and BrdU staining for each group are shown. BrdU was administered 2 h before collection. d. Quantification of TUNEL positive cells and BrdU positive cells per field in DMSO or IC-261 treated xenograft tumors. Error bars indicate SD of means.

[0014] FIGS. 4A-4F. CSNK1e expression correlates with poor prognosis and MYCN amplification in neuroblastoma. a, Kaplan-Meier survival curves of neuroblastoma patients divided on the basis of CSNK1e expression; lower solid line indicates high and upper solid line indicates low CSNK1e mRNA expression based on microarray data accessible at the Oncogenomics neuroblastoma prognosis database. b, Graphical representation of expression intensities for CSNK1e mRNA derived from microarray data of neuroblastoma tumor samples. Each bar represents one sample. The shaded horizontal line (-MYCN ampl.) indicates samples derived from MYCN amplified neuroblastoma c. Representative western blot of CSNK1e, MYCN and .beta.-actin (loading control) protein levels in SN-N-AS (MYCN not amplified), SK-N-BE2 and IMR-32 (MYCN amplified) neuroblastoma cells. d, Representative western blot of CSNK1e, MYCN and .beta.-actin (loading control) protein levels in HFF pB and HFF c-Myc cells. e, Representative western blot of CSNK1e, MYCN and .beta.-actin (loading control) protein levels in Tet21N (MYCN Tet-Off) cells. f, Real time RT-PCR quantification of the relative levels of each casein kinase I isoforms normalized to glyceraldehydes-3-phosphate dehydrogenase (GAPDH) mRNA levels in neuroblastoma cell lines with or without MYCN amplification. The bars for each isoform, from left to right, refer to SK-N-AS, SH-SY-SY, LAN-5, IMR-32, KCN, KCNR, SK-N-BE2 neuroblastoma cell lines.

[0015] FIG. 5. Network analysis of MYC-SL "Hits" (dashed) and their connection with a pre-assembled MYC "core" pathway (dark shading). The network was built to visualize known literature connections between the "Hits" (dashed) and a pre-assembled MYC core pathway (solid). All connections were drawn based on Ingenuity curated database. Only the MYC-SL with known direct connections with the MYC core components are here visualized. Each line represents a single reference and the connecting lines indicate the interaction. Arrows mark genes referred to in the text.

[0016] FIG. 6. Conditional knock-down of CSNK1e with lentiviral expressed short hairpins does not affect expression of other CSNK1e isoforms.

[0017] Relative mRNA expression of CSNK1 A (.alpha.), G1 (.gamma.1), G2 (.gamma.2), G3 (.gamma.3) and D (.delta.) in SKNBE2 cells were transduced with lentiviral vectors expressing shCSNK1e#1 and #2 (see FIG. 2) and either treated or untreated with Doxycycline for 48 hrs. Relative levels of each gene were calculated using the .DELTA..DELTA.CT method and using GAPDH to normalize mRNA levels within each sample.

[0018] FIGS. 7A-7D. Chemical inhibition of CSNK1e kinase activity shows selective toxicity to MYC overexpressing cells.

[0019] a. HFF cell lines with or without c-Myc over-expression were treated with 0-10 uM IC261 for 48 hrs. The cells were exposed to CellTiter-Glo reagent and viability was assessed by ATP-induced chemiluminescence. Values indicate mean.+-.SD. b. Tet21N cells with or without doxycyclin treatment and IMR-32 cells (MYCN+) were treated with 0-30 uM IC261 for 48 hrs. The cells were exposed to CellTiter-Glo reagent and the viability was assessed by ATP-induced chemiluminescence. Values indicate mean.+-.SD. c. Cell growth curves for HFF-pBabe incubated with different concentrations of IC261. d. Cell growth curves for HFF-MYC incubated with different concentrations of IC261.

[0020] FIG. 8. The CSNK1e gene contains MYC-MAX consensus sites. The DNA sequence surrounding the transcription start site as well as the first and second intron of CSNK1e contains several MYC-MAX potential binding sites.sup.41 both upstream and downstream from the transcription start site.

DETAILED DESCRIPTION

[0021] Embodiments of the present invention relate to the discovery of druggable gene targets in MYC-driven cancers, and related methods of inhibiting the growth and/or proliferation of myc-driven cancer cells by targeting one or more of these genes or their encoded protein(s) with inhibitory agent(s), including small molecule inhibitors of the protein(s). Also included are methods using such inhibitors to treat a subject having a MYC-driven cancer. In particular aspects, the cancer is a c-MYC-driven or a MYCN-driven cancer, such as a c-MYC-amplified or a MYCN-amplified cancer, and the gene (or its encoded protein) targeted for inhibition is described in Table 1 or 2.

DEFINITIONS

[0022] Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by those of ordinary skill in the art to which the invention belongs. Although any methods and materials similar or equivalent to those described herein can be used in the practice or testing of the present invention, preferred methods and materials are described. For the purposes of the present invention, the following terms are defined below.

[0023] The articles "a" and "an" are used herein to refer to one or to more than one (i.e., to at least one) of the grammatical object of the article. By way of example, "an element" means one element or more than one element.

[0024] By "about" is meant a quantity, level, value, number, frequency, percentage, dimension, size, amount, weight or length that varies by as much as 30, 25, 20, 15, 10, 9, 8, 7, 6, 5, 4, 3, 2 or 1% to a reference quantity, level, value, number, frequency, percentage, dimension, size, amount, weight or length.

[0025] Throughout this specification, unless the context requires otherwise, the words "comprise," "comprises," and "comprising" will be understood to imply the inclusion of a stated step or element or group of steps or elements but not the exclusion of any other step or element or group of steps or elements. By "consisting of" is meant including, and limited to, whatever follows the phrase "consisting of" Thus, the phrase "consisting of" indicates that the listed elements are required or mandatory, and that no other elements may be present. By "consisting essentially of" is meant including any elements listed after the phrase, and limited to other elements that do not interfere with or contribute to the activity or action specified in the disclosure for the listed elements. Thus, the phrase "consisting essentially of" indicates that the listed elements are required or mandatory, but that other elements are optional and may or may not be present depending upon whether or not they materially affect the activity or action of the listed elements.

[0026] "Cancer" relates generally to a class of diseases or conditions in which a group of cells display one or more of uncontrolled growth (i.e., division beyond normal limits), invasion (i.e., intrusion on and destruction of adjacent tissues), and/or metastasis (i.e., spread to other locations in the body via lymph or blood). These malignant properties of cancers differentiate them from benign cancers, which are self-limited, and typically do not invade or metastasize.

[0027] A "cancer cell" or "tumor cell" refers to an individual cell of a cancerous growth or tissue. A tumor refers generally to a swelling or lesion formed by an abnormal growth of cells, which may be benign, pre-malignant, or malignant. Most cancers form solid tumors, but some, e.g., leukemia, do not necessarily form tumors. For those cancers that form tumors, the terms cancer (cell) and tumor (cell) are used interchangeably.

[0028] As used herein, the terms "function" and "functional" and the like refer to a biological, enzymatic, or therapeutic function.

[0029] The term "gene" refers to a locatable region of genomic sequence, corresponding to a unit of inheritance, which is associated with regulatory regions, transcribed regions, and or other functional sequence regions. A gene optionally encodes for a protein or polypeptide that has at least one function in an organism.

[0030] The terms "modulating" and "altering" include "increasing," "enhancing" or "stimulating," as well as "inhibiting," "decreasing" or "reducing," typically in a statistically significant or a physiologically significant amount or degree relative to a control. An "increased," "stimulated" or "enhanced" amount is typically a "statistically significant" amount, and may include an increase that is 1.1, 1.2, 2, 3, 4, 5, 6, 7, 8, 9, 10, 15, 20, 30 or more times (e.g., 500, 1000 times) (including all integers and decimal points in between and above 1, e.g., 1.5, 1.6, 1.7, 1.8, etc.) the amount produced by no composition (e.g., the absence of polypeptide of conjugate of the invention) or a control composition, sample or test subject. A "decreased" or "reduced" amount is typically a "statistically significant" amount, and may include a 1%, 2%, 3%, 4%, 5%, 6%, 7%, 8%, 9%, 10%, 11%, 12%, 13%, 14%, 15%, 16%, 17%, 18%, 19%, 20%, 25%, 30%, 35%, 40%, 45%, 50%, 55%, 60%, 65%, 70%, 75%, 80%, 85%, 90%, 95%, or 100% decrease in the amount produced by no composition or a control composition, including all integers in between. As one non-limiting example, a control could compare the growth and/or proliferation of a MYC-driven tumor cell after being contacted with an inhibitor that inhibits the gene function of a gene listed in Table 1 or 2, relative to the growth and/or proliferation of a normal/healthy of the same or similar type, or relative to the growth and/or proliferation of a non-MYC-driven tumor of the same or similar type, after being contacted with that same inhibitor. Other examples of comparisons and "statistically significant" amounts will be apparent to persons skilled in the art from the description provided herein.

[0031] The term "MYC" refers to the Myc family of transcription factors, including c-MYC (encoded by the MYC gene) and N-MYC (or MYCN; encoded by the MYCN gene). A "MYC-driven" cancer cell or cancer cell derived therefrom includes a cancer cell that has increased expression and/or activity of at least one Myc transcription factor such as c-MYC and/or MYCN, relative to a control cell such as a normal (e.g., non-cancerous) cell of the same or corresponding cell type. As one example, a "MYC-driven" cancer cell includes a "MYC-amplified" or "MYCN-amplified" cancer cell, such as a cell that has an increase (1.5.times., 2.times., 3.times., 4.times., etc.) in the number of copies (e.g., 1, 2, 3, 4, 5, 6 copies) of a MYC and/or a MYCN gene, optionally without a proportional increase in other genes.

[0032] By "statistically significant," it is meant that the result was unlikely to have occurred by chance Statistical significance can be determined by any method known in the art. Commonly used measures of significance include the p-value, which is the frequency or probability with which the observed event would occur, if the null hypothesis were true. If the obtained p-value is smaller than the significance level, then the null hypothesis is rejected. In simple cases, the significance level is defined at a p-value of 0.05 or less.

[0033] A "subject," as used herein, includes any animal that has a cancer or exhibits a symptom or cancer, or is at risk for having a cancer or exhibiting a symptom of cancer, which can be treated by inhibiting the function of a gene described herein (see Table 1 and Table 2). Suitable subjects (patients) include laboratory animals (such as mouse, rat, rabbit, or guinea pig), farm animals, and domestic animals or pets (such as a cat or dog). Non-human primates and, preferably, human patients, are included. In certain aspects, prior to treatment with an inhibitor described herein, a subject is first identified as having a MYC-driven cancer or tumor, for instance, by measuring the expression levels and/or number of gene copies of a Myc transcription factor, such as MYC and/or MYCN. In some aspects, the subject is monitored before, during, and/or after treatment for the presence of a MYC-driven cancer or tumor, and the treatment is adapted accordingly.

[0034] "Substantially" or "essentially" means nearly totally or completely, for instance, 95%, 96%, 97%, 98%, 99% or greater of some given quantity.

[0035] "Treatment" or "treating," as used herein, includes any desirable effect on the symptoms or pathology of a disease or condition such as a MYC-driven cancer, and may include even minimal changes or improvements in one or more measurable markers of the disease or condition being treated. "Treatment" or "treating" does not necessarily indicate complete eradication or cure of the disease or condition, or associated symptoms thereof. The subject receiving this treatment is any subject in need thereof. Exemplary markers of clinical improvement will be apparent to persons skilled in the art.

[0036] The term "wild-type" refers to a gene or gene product that has the characteristics of that gene or gene product when isolated from a naturally-occurring source. A wild type gene or gene product (e.g., a polypeptide) is that which is most frequently observed in a population and is thus arbitrarily designed the "normal" or "wild-type" form of the gene.

Inhibition and Treatment of MYC-Driven Cancers

[0037] Drugs directed toward oncoproteins have demonstrated therapeutic efficacy while avoiding systemic toxicities associated with standard chemotherapeutics. However, the MYC family of oncoproteins, which are broadly implicated in many human cancers, are difficult to inhibit with small molecules or antibody based therapies. To target MYC-driven cancers, we have taken the approach of identifying druggable genes that exhibit a synthetic lethal relationship with aberrant MYC expression. Using an isogenic cell model system, we identified, via high throughput siRNA screening, more than 100 druggable genes that exhibit a synthetic lethal interaction with MYC (referred to as MYC-synthetic lethal genes, MYC-SL). Among the MYC-SL genes, we focused on casein kinase 1 epsilon (CSNK1e), whose relevance in MYC-driven human cancer was demonstrated by correlation between high levels of CSNK1e expression, MYCN amplification, and poor clinical prognosis in neuroblastoma cases. The requirement of CSNK1e for growth of neuroblastomas with MYCN amplification was validated in vivo by conditional knock-down and via a small molecule inhibitor of its activity. Thus, our studies show how high throughput siRNA screening can be used to identify a network of synthetic lethal genes and potential new therapeutic targets functionally linked to a previously un-druggable oncogene.

[0038] The MYC oncogene is a central driver in many human cancers, and its amplification is associated with poor prognosis in breasts.sup.1 2 prostate .sup.3 4, colon and pediatric cancers such as neuroblastoma (for review see .sup.6). In addition, c-MYC overexpression, together with gene amplification has been reported in over 50% of ovarian cancers .sup.7, in .about.30% of hepatocellular carcinoma .sup.8, and in a high percentage of small-cell and non-small-cell lung cancer .sup.9. Such a high frequency of MYC family deregulation in human cancers suggests that a strategy to target MYC-driven cancers may be relevant for the treatment of a broad population of patients. Recently, systemic inhibition of MYC utilizing a transgenic mouse model has demonstrated the efficacy of a dominant negative MYC in mediating tumor regression .sup.10. However, MYC family members encode for transcription factors without obvious druggable domains .sup.11 rendering the identification of small molecule inhibitors a challenge .sup.12. In addition, as MYC oncoproteins carry out essential functions in proliferative tissues .sup.13, prolonged inhibition of MYC function could cause severe side effects. Rather than targeting MYC itself, we elected to apply a functional genomic screen to identify druggable genes that are preferentially required for survival of MYC overexpressing cells. To avoid the genetic noise inherent in cancer cells, we chose to screen an isogenic pair of primary cells, where the only perturbation was overexpression of c-MYC through a retroviral vector .sup.14. Human foreskin fibroblasts (HFFs) are unique in that they do not senesce in response to MYC overexpression .sup.14 or activated Ras .sup.15, a property that has been attributed to lack of culture stress. Furthermore, c-MYC overexpression in HFFs recapitulates both the gene expression signature and cellular phenotypes of MYC-driven cancers (.sup.14 16 17 and CG unpublished observations).

[0039] siRNA Screening to Identify a Network of Genes Required for Survival of c-MYC Overexpressing Cells

[0040] We employed a high throughput robotics-based approach for massive parallel testing of an arrayed siRNA library to accurately quantify the effects of siRNAs against .about.3,300 druggable genes and 200 microRNAs on the viability of HFF-MYC (stably transduced with a retroviral vector expressing c-MYC), or a control empty vector, HFF-pB .sup.14, see FIG. 1a for schematic of the experimental set-up). The siRNA library collection was selected so as to target all known human kinases, ubiquitin ligases, DNA repair proteins and a custom collection of genes involved in cancer pathways, with each target gene being interrogated by a pool of three unique siRNAs (SIGMA and Rosetta-Merck custom collection). Three technical replicates and the one gene/well approach enabled derivation of hits with statistical significance for each gene tested, similarly to what has been shown for other biological systems .sup.18 19. Cell viability was assessed using Alamar Blue staining, and quantified using an EnVision plate reader (Perkin-Elmer). The results of the screen revealed 148 hits comprised of 140 genes and 8 microRNAs, defined according to a Z score .gtoreq.2.sup.20 (FIG. 1b). Here, we will only focus on gene hits, referred to as MYC synthetic lethal (MYC-SL) genes. To eliminate siRNAs that despite their differential toxicity exhibited substantial growth inhibition properties in normal cells, siRNAs with >50% reduced viability in HFF-pB were eliminated. This process left 102 MYC-SL gene hits for follow up (Table 2).

[0041] Network analysis identified known literature connections (based on Ingenuity curated database) between the "Hits" (light shading) and a pre-assembled MYC core pathway (dark shading) as shown in FIG. 5. About 50% of the MYC-SL hits had known functional connections with MYC and functionally related genes. For example TRRAP is a direct MYC binding partner that mediates recruitment of histone acetylase to selective MYC bound promoters .sup.21 22. Several MYC-SL hits were linked to the basic transcriptional machinery (see TBP node in FIG. 5) including POLR2E, POLR2I, and GTF2H4. CDK2, was also identified as MYC-SL, a finding consistent with its essential role in limiting MYC-induced senescence in a mouse model of tumorigenesis .sup.23. Additionally, the identification of PES1 (a gene involved in ribosomal biogenesis) among MYC-SL, is consistent with the direct stimulation of ribosomal RNA synthesis by c-MYC .sup.16 24 and by the "addiction" to elevated ribosomal function demonstrated by the suppression of MYC oncogenicity through ribosomal protein haploinsufficiency in mice .sup.25. The broad spectrum of potential MYC-SL genes thus reflects known MYC functions linked to not only to chromatin modification (TRRAP, BRD4, CECR2,) and to ribosomal biogenesis (PES1), but also metabolism (AldoA, PDK1), DNA repair (DDB2, GTF2H4, NEIL1, POLH, RAD21), apoptosis (BNIP2, BOK, MCL1), and mitotic control (WEE1, NEK2) (see FIG. 5 and Table 2).

[0042] We selected 49 MYC-SL genes based upon best predicted druggability, their potential involvement in cancer pathways and their ranking in the screen in terms of differential toxicity, for follow up Impressively, 48 out of the 49 tested genes were confirmed with more than one siRNA and in an additional matched pairs of HFFs (98% confirmation rate, see Table 1 for the list of validated and selected MYC-SL), thus highlighting the robustness of our initial screening process. Twelve MYC-SL hits, PES1, CECR2, CSNK1e, MYLK, TXK, TIE1, CDK2, PRKCL1, TRRAP, MAP3K13, NEK2 and WEE1 were assessed via stable, lentiviral-mediated shRNA knock-down, confirming their differential growth inhibition in HFF-MYC versus HFF-pB control (FIG. 1 c-d, and data not shown). Examination of selective toxicity in HFF-MYC cells was carried out for 38 genes by assessing levels DNA damage and apoptosis. siRNA-mediated knock-down of twelve (25%) of the hits resulted in elevated .gamma.-H2AX foci only in HFF-MYC but not HFF cells. This indicates that induction of DNA damage is a significant consequence of the MYC-synthetic lethal interaction (FIG. 1e for representative images and if for quantitation; summarized in Table 1). This finding is consistent with the role of MYC in promoting genomic instability .sup.26 and replication associated damage due to an acceleration of S-phase .sup.17 27. Additionally, 34 of the 48 MYC-SL genes (>70%) induced caspase-3 and 7 cleavage in HFF-MYC but not in HFF-pB upon siRNA transfection (FIG. 2g, Table 1) Importantly, our ability to recapitulate the results from the original high-throughput screen using a combination of three knockdown protocols (siRNA pools, deconvoluted siRNA pools, and lentiviral shRNAs) as well as independent assays suggests that our screening protocol was not only comprehensive but also robust and accurate in predicting MYC-SL genes.

[0043] Casein Kinase 1 Epsilon is a MYC-SL Gene in Preclinical Models of Neuroblastoma

[0044] We next wished to validate the MYC-SL genes in neuroblastoma cell lines with or without MYCN amplification, as a model of MYC-driven cancer .sup.28. In humans, amplification of MYCN in neuroblastoma is the strongest molecular marker of poor prognosis and is utilized for treatment stratification .sup.29. The potential conservation of synthetic lethal interactions with both c-MYC and MYCN is supported by the fact that MYCN and c-MYC control a similar set of target genes and cellular phenotypes .sup.30 31, and that c-MYC can replace MYCN during murine development .sup.32. We screened neuroblastoma cell lines with (IMR-32) or without (SK-N-AS) MYCN amplification with siRNAs targeting the selected 48 MYC-SL genes. 11 MYC-SL genes exhibited selective lethality in MYCN amplified neuroblastomas (indicated with shading in the first column of Table 1), indicating conserved synthetic lethal interaction with both MYC family members and in a cancer cell setting. We chose to focus on one of these genes, Casein kinase 1 epsilon (CSNK1e) for preclinical validation because siRNAs and stable knock-down had showed minimal toxicity to normal HFFs (FIG. 1), suggesting the possibility of a good therapeutic window. Moreover, pharmacologic inhibitors were readily available, enabling us to verify that blocking its enzymatic activity would mimic the effect of gene knock-down .sup.33. We first tested the differential growth inhibition in MYCN amplified neuroblastoma cells in vitro, using conditional lentiviral vectors targeting CSNK1e with two different short hairpins (sh#1, and sh#2, FIGS. 2a, b and c). As there are six isoforms of CSNK1, the specificity of the lentiviral-expressed short hairpins was examined by assessing the relative levels of mRNA expression of the other isotypes. CSNK1e-specific short hairpins reproducibly lowered the expression of the epsilon isoform, but had no effect on the mRNA expression of the other isoforms (FIG. 6). As a pre-clinical validation model, neuroblastoma cells were transduced in vitro with either a control sh expressing lentiviral vector or shCSNK1e #1 and injected into the flanks of immunodeficient mice. Once tumors became engrafted and had reached a minimal size of .about.>100 mm.sup.3, mice were exposed to doxycycline and tumor growth was measured over time. As shown in FIG. 2d, neuroblastoma growth was significantly impaired in 3 out of 4 treated mice, validating the MYC-synthetic lethal relationship of CSNK1e knock-down in vivo.

[0045] As there is strong selection to escape lentiviral-mediated silencing of genes that are necessary for cell growth, we proceeded to evaluate a small molecule inhibitor of CSNK1e enzymatic activity, IC261 .sup.33. In vitro experiments had indicated that MYC overexpressing cells were indeed more sensitive to IC261 relative to normal or low MYC expressing cells, with >100 fold differences in IC50 (FIGS. 7a and 7b). IMR32 (MYCN+) cells were utilized as a therapeutic xenograft model as they were established in culture prior to patient chemotherapy and were highly sensitive to IC261 in vitro (FIG. 7b). A cohort of ten xenograft bearing mice was randomized into two groups with approximate equal tumor burden; one group was treated with daily subcutaneous injection of IC261 for 8 consecutive days, while the control group was treated with DMSO vehicle only. A photograph of a representative mouse from each group before and after treatment is shown in FIG. 3a Importantly, IC261 was effective in halting tumor growth in all treated mice (FIG. 3b). Histopathological examination of the tumor tissue remaining after IC261 treatments, indicated a pronounced proliferative defect as indicated by the marked decrease in BrdU labeling, while very little apoptosis was detected via TUNEL staining (FIGS. 3c and d). This result is consistent with the observation that CSNK1e knock-down did not induce prominent caspase-3 or 7 cleavage in HFFs (FIG. 1g). Taken together, the results obtained by genetic knock-down as well as via small molecule inhibitor validate CSNK1e as a potential therapeutic target for MYCN-driven neuroblastoma.

[0046] Importantly, CSNK1e expression correlates with both MYCN amplification and poor prognosis in primary neuroblastomas (FIGS. 4a and b). The correlation of high CSNK1e expression in MYCN+ neuroblastoma at the protein level was confirmed in three representative cell lines (FIG. 4c) and at the RNA level in these and additional cell lines (FIG. 4f). Among the six CSNK1 isoforms, tested, epsilon, was predominantly expressed in lines with MYCN amplification .sup.34 (FIG. 4f). These findings, as well as the presence of potential MYC-MAX binding sites in the promoter region of CSNK1e (FIG. 8) suggest a direct regulation of CSNK1e mRNA by c-MYC/MYCN. Consistent with this, CSNK1e is upregulated in both HFF-MYC (FIG. 4d) and upon induced MYCN expression in the neuroblastoma cell line Tet21N .sup.35 (FIG. 4e). Together, these data support the model where MYC overexpression stimulates expression of CSNK1e, which is in turn required for its survival. In this scenario, CSNK1e represents an "induced dependency" of MYC overexpressing cells. This finding is reminiscent of a previously identified functional dependency of MYC overexpressing cell upon one of its direct transcriptional targets, the Werner syndrome gene (WRN).sup.36.

[0047] Identifying a means to target oncogenic transcription factors as a cancer treatment remains a challenging goal, due to the non-druggability of these proteins, and their essential cellular functions in non-cancerous tissue. Here, we have identified druggable genes that are synthetically lethal in the context of high MYC expression. These genes include those known to be involved in MYC-dependent processes, as well as genes not previously identified as part of the MYC pathway. We focused on CSNK1e, a gene with no previous functional links with MYC, which we validated as a candidate therapeutic target in neuroblastoma with MYCN amplification. The potential that CSNK1e could represent a therapeutic target in other MYC-driven cancers is likely, as its expression is not restricted to HFFs or neuroblastoma, and unpublished results indicate its synthetic lethal interaction with MYC overexpression/amplification is observed in other cancer contexts.

[0048] CSNK1e has been previously implicated in the regulation of WNT and SHH signaling. Consistent with the potential for CSNK1e to affect WNT signaling, meta-analysis of gene expression in neuroblastoma tumors indicated that both Frizzeld (FZL) and its the ligand WNT10 were found elevated in MYCN+ stage 4 neuroblastoma versus stage 4 MYCN- tumors, while DKK3, a WNT inhibitor, was found to be repressed (CG, unpublished observations). This finding supports the conclusion from studies in breast cancer where WNT signaling has been shown to be stimulated by MYC overexpression .sup.37. Moreover, GLI1, the well-studied mediator of SHH signaling, was among the hits in the HFF screen, while the receptor for SHH, smoothened (SMO), was also found elevated in MYCN+ neuroblastoma by meta-analysis. Thus, it is possible that CSNK1e activity might be essential for survival of cells with MYCN amplification through its activity on both developmental pathways. During the course of this work, two publications involving functional screens also identified CSNK1e as a target to block proliferation of colon cancer and breast cancer with WNT-deregulation .sup.38 39. In addition, a functional genomic screen carried out in human fibrosarcoma lines identified CSNK1e as a "hit" that differentially affected viability of transformed fibroblasts .sup.40. Together, these findings indicate the relevance of CSNK1e in other cancer contexts and it reinforces the value of functional genomics to reveal cancer therapeutic targets, which might be missed by sequencing approaches.

[0049] In summary, here we have demonstrated an efficient pipeline, which combines the power of a robust high throughput functional genomics approach with a biological controlled cell systems, to reveal candidates for therapeutic development toward un-druggable oncogenic targets. This approach can be supplemented through the use of arrayed lentiviral libraries to enable long-term knock-down. For example, the screen did not detect the dependency of MYC upon expression of the WRN gene, likely due to the high stability of the WRN protein and mRNA and the need for HFFs to undergo several cell divisions under WRN depletion prior entering cellular senescence .sup.36. Our study utilizing siRNAs has uncovered several genes that represent critical survival pathways for cancers with MYC overexpression/gene amplification. Many of these genes were not previously known to have an interaction with the MYC oncoprotein. Targeting these genes provides novel therapeutic opportunities for proliferative tissues. Inhibitors of the genes have valuable potential as cancer therapeutics. Additionally, the genes identified herein constitute biomarkers for MYC-driven cancers that can guide therapeutic choices or suggest drug combinations for maximum therapeutic effect.

Tables

TABLE-US-00001

[0050] TABLE 1 List of MYC-synthetic lethal genes. The effect of siRNAs pools targeting these genes was confirmed through pool deconvolution and testing in independent HFF cell pairs. 48 out of 49 gene hits tested, which confirmed selective growth inhibition in an additional pair of matched HFF-c-MYC and control HFF-pB and with more than one siRNA upon deconvolution of the siRNA pool used in the screen. % % % Gene Viability Viability Viability Apoptosis H2AX Symbol HFF-pB HFF-MYC PB/MYC positive positive Functional Annotations ##STR00001## 59.31 13.85 4.28 yes yes Aldolase A cleaves fructose- 1,6-bisphosphate, glycolysis ARFGEF2 54.66 3.29 16.62 no no ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A- inhibited) BOK 74.57 18.12 4.12 yes no BCL2-related ovarian killer, apoptosis in response to DNA damage via TP53 pathway BTK 57.41 8.38 6.85 NT NT Bruton agammaglobulinemia tyrosine kinase pre-B cell receptor signaling and B cell development CAMK1G 64.77 24.63 2.63 yes no Calcium/calmodulin- dependent protein kinase IG, highly expressed in brain CAMK2D 62.00 17.64 3.51 NT NT Calcium-calmodulin- dependent protein kinase (CaM kinase) II delta CDK2 54.01 19.41 2.78 yes no Cyclin-dependent protein kinase 2 ##STR00002## 80.97 28.42 2.85 yes no Cat eye syndrome chromosome region candidate 2, an ATPase that interacts with SNF2L (SMARCA1) CRKRS 59.16 16.71 3.54 yes no Cdc2-related kinase arginine- serine-rich, an SR domain- and proline-rich region- kinase, t phosphorylates the C-terminal domain of RNA polymerase II ##STR00003## 76.69 28.59 2.68 yes no Casein kinase 1 epsilon, regulates Wnt receptor signaling and circadian clock CTPS 70.57 19.44 3.63 yes no CTP synthetase, inhibited by cyclopentenyl cytosine, increased expression in T- ALL FBXO5 70.44 25.28 2.79 yes yes F-box containing proteins, subunit of the SCF ubiquitin lipase complex GLI1 58.54 25.07 2.33 yes yes Glioma-associated oncogene homolog 1, member of the GLI-Kruppel transcriptional activators of the SHH GTF2H4 73.10 18.01 4.06 NT NT General transcription factor IIH polypeptide 4 52kDa, functions in transcription and nucleotide excision repair HCK 67.95 16.98 4.00 yes no Hematopoietic cell kinase, a Src family tyrosine kinase involved in signaling, phagocytosis and cell shape changes HECTD3 62.93 28.52 2.21 NT NT HECT domain containing protein with similarity to human HERC1, which acts as a guanine-nucleotide exchange factor for ARF1 and Rab related proteins HSD17B4 70.05 21.83 3.21 NT NT Type IV 17 beta- hydroxysteroid dehydrogenase, a peroxisomal multifunctional enzyme involved in steroid and bile acid metabolism ##STR00004## 58.76 15.43 3.81 yes no Insulin-like growth factor II receptor, a receptor tyrosine- kinase IRS2 72.71 28.46 2.55 yes no Insulin receptor substrate 2, mediates signal transduction for insulin, integrin, and cytokines, may be associated with type 2 diabetes and carcinoma cell invasion MAP2K3 56.31 16.88 3.34 yes no Mitogen activated protein kinase kinase 3, phosphorylates MAP kinase p38, involved in stress and inflammatory responses, senescence, apoptosis MAP2K7 98.97 43.13 2.29 NT NT Mitogen-activated protein kinase kinase 7,c-Jun N- terminal kinase kinase 2 MYLK 89.77 13.70 6.55 no no Myosin light polypeptide kinase, calcium and calmodulin-dependent kinase, lamellipodia protrusion/retractions NEIL1 77.77 28.16 2.76 yes no Nei endonuclease VIII-like 1, an endonuclease with DNA glycosylase and lyase activities toward mismatched or oxidized nucleotides, S phase-specific activation NEK2 62.97 27.57 2.28 yes no NIMA-related kinase 2, involved in centrosome cycle during mitosis, inhibits protein phosphatase 1 ##STR00005## 64.80 20.78 3.12 NT NT p21(CDKN1A)-activated kinase 6, activated by MAP kinases, interacts with steroid hormone receptors and suppresses receptor-mediated transcriptional activation PCBD1 64.08 23.88 2.68 yes no Pterin 4 alpha carbinolamine dehydratasc, co-activator for TCF1, altered expression is associated with hyperphenylalaninemia, vitiligo, and colorectal ca. ##STR00006## 51.38 14.28 3.60 yes no Pescadillo homolog containing BRCT domain 1, role in transformation, rRNA synthesis, neural crest migration PIK4CB 58.97 25.54 2.31 yes no Phosphatidylinositol 4-kinase catalytic beta polypeptide, a wortmannin-sensitive lipid kinase PKN1 86.39 32.82 2.63 yes no Protein kinase, activated by Rac, Rho and fatty acids, stimulates phospholipase D1 and PLC activity, regulates G2-M and cytoskeletal function POLH 84.32 28.71 2.94 yes no DNA polymerase eta, acts in DNA damage checkpoint by regulating p53(TP53) activation; gene is mutated in xeroderma pigmentosum POLR2E 77.27 31.46 2.46 yes no RNA Polymerase II DNA directed polypeptide E 25kD, subunit of RNA polymerases I, II, III, involved in transcriptional activation PRC1 60.94 15.68 3.89 yes yes Regulator of cytokinesis 1, associates with the mitotic spindle, required for cytokinesis but not nuclear division, microtubule bundling ##STR00007## 62.63 16.73 3.74 yes yes RAD21 homolog, sister chromatid separation, chromatid cohesion, G2-M cell cycle arrest, and cytokinesis, upregulated in prostrate cancer, and breast ca. RAGSRF1 97.27 42.12 2.31 no no Ras protein specific guanine nucleotide releasing factor 1, similar to the Saccharomyces cerevisiae CDC25 RASSF7 109.39 17.15 6.38 yes no helix-loop-helix motif, and a leucine zipper dimerization motif with four heptad repeats ##STR00008## 76.20 13.26 5.75 yes no REV1-like (yeast), a DNA template-dependent dCMP transferase, extends primer strand in mutagenic translesion DNA synthesis SDC4 70.19 21.12 3.32 NT NT Syndecan 4, regulates inositol phospholipid binding and signaling, protein kinase C activation SULT1A2 70.56 22.63 3.12 yes yes Sulfotransferase cytosolic 1A phenol-preferring member 2, sultanates para-nitrophenol; polymorphism associated with early onset breast cancer risk ##STR00009## 67.94 3100 2.19 yes yes Suppressor variegation 3-9 homolog 1, histone methyltransferase that of histone H3 on lysine 9, represses transcription by interaction with RB1 ##STR00010## 74.99 23.57 3.18 yes yes Tyrosine kinase with immunoglobulin-like and EGF-like domains 1, a putative tyrosine kinase receptor, angiopoietin R, upregulated in invasive cancers TRIB1 57.34 17.24 3.33 yes yes Phosphoprotein regulated by mitogenic pathways, a putative kinase that interacts with and may regulate 12- lipoxygenase (ALOX12) TRRAP 81.13 31.33 2.59 yes no ATM-related protein, a component of a multiprotein historic acetyltransferase complex essential for MYC and E2F transcription factor pathways TXK 96.42 15.71 6.14 no no Tec-Src kinases that lack the pleckstrin domain, activates MAPK, positively regulate interferon gamma (IFNG) transcription, binds PARP1 UBE2I 52.17 15.08 3.46 yes yes Ubiquitin-conjugating enzyme E2I UBC9 homolog yeast, SUMO-1 (UBL1) conjugating enzyme WEE1 62.12 28.85 2.15 yes yes WEE1 homolog, a tyrosine kinase that regulates the G2 mitotic checkpoint and nucleocytoplasmic transport WEE2 84.88 29.99 2.83 yes yes homologue of WEE1 YES1 68.36 22.16 3.08 NT NT Yamaguchi sarcoma viral oncogene homolog 1, a nonreceptor protein tyrosine kinase of the Src family, functions downstream of GM-CSF (CSF2) Shaded in "Gene Symbol" column: confirmed selective lethality in MYCN+ versus MYCN- neuroblastoma secondary screen "no" in "Apoptosis positive" and "H2AX positive" columns: scored negative for either apoptosis or y-H2AX staining "yes" in "Apoptosis positive" and "H2AX positive" columns: scored positive for either apoptosis or y-H2AX staining *only 1 siRNA of the original pool was active, but confirmed by stable knock-down

TABLE-US-00002 TABLE 2 List of all gene hits here referred to as MYC-SL. 102 genes out of 148 hits remained after siRNAs with percent viability of less then <50% in control HFF-pB were eliminated. microRNAs are also not listed here. The indicated % viability is the average of 3 replicates and is expressed as percent viability relative to the median value of wells transfected with an siRNA to luciferase. Hits were determined by Z score =>2, calculated as described .sup.20 The last column refers to the ratio of percent viability of a given siRNA pool in HFF-pB/HFF-MYC. The nucleotide sequence for each gene is hereby incorporated by reference to the Genbank accession number, as accessed on Aug. 9, 2011 (listed in the second column). Accession Z score % Viability % Viability Ratio SEQ ID Gene Symbol number (>than) HFF-pB HFF-MYC pBabe/Mye NO: ADRBK2 NM_005160 2 66.14 30.55 2.17 1 ALDOA NM_000034 2.5 59.31 13.85 4.28 2 ALPK1 NM_025144 2.5 59.67 21.80 2.74 3 AMID NM_032797 2 93.61 47.65 1.96 4 APBA2BP NM_031231 2.5 74.31 25.88 2.87 5 APEG1 NM_005876 2.5 67.41 20.36 3.31 6 ARFGEF2 NM_006420 2.5 54.66 3.29 16.62 7 ASCC3L1 NM_014014 2.5 55.94 18.89 2.96 8 ATP5D NM_001687 2 83.38 35.32 2.36 9 BMPR1A NM_004329 2 61.70 30.02 2.06 10 BNIP2 NM_004330 2 56.13 26.07 2.15 11 BOK NM_032515 2.5 74.57 18.12 4.11 12 BRD4 NM_014299 2 60.05 28.99 2.07 13 BTK NM_000061 2.5 57.41 8.38 6.85 14 C17orf49 BC040036 2.5 83.05 26.24 3.17 15 C1orf117 NM_182623 2.5 75.21 15.91 4.73 16 CAMK1G NM_020439 2.5 64.77 24.63 2.63 17 CAMK2D NM_001221 2.5 62.00 17.64 3.51 18 CAMK2G NM_172171 2 99.46 38.96 2.55 19 CCNK BC015935 2 51.64 21.59 2.39 20 CDH5 NM_001795 2.5 60.30 24.99 2.41 21 CDK2 NM_001798 2.5 54.01 19.41 2.78 22 CECR2 AB051527 2 80.97 28.42 2.85 23 CPS1 NM_001875 2 58.12 25.10 2.32 24 CRADD NM_003805 2.5 49.68 21.30 2.33 25 CRKRS NM_016507 2.5 59.16 16.71 3.54 26 CSNK1E NM_001894 2 76.69 28.59 2.68 27 CTPS NM_001905 2.5 70.57 19.44 3.63 28 CTSD NM_001909 2 66.42 36.06 1.84 29 CXXC1 NM_014593 2.5 49.66 18.00 2.76 30 DDB2 NM_000107 2 69.50 27.21 2.55 31 EFNA5 NM_001962 2 65.45 27.30 2.40 32 FBXO5 NM_012177 2.5 70.44 25.28 2.79 33 GLI1 NM_005269 2.5 58.54 25.07 2.33 34 GNRHR NM_000406 2 66.69 31.96 2.09 35 GRK1 NM_002929 2 59.11 29.62 2.00 36 GSG2 NM_031965 2 60.67 28.26 2.15 37 GTF2H4 BC004935 2.5 73.10 18.01 4.06 38 HCK NM_002110 2.5 67.95 16.98 4.00 39 HECTD3 NM_024602 2.5 62.93 28.52 2.21 40 HPS1 NM_000195 2 66.79 28.63 2.33 41 HSD17B4 NM_000414 2.5 70.05 21.83 3.21 42 ICT1 NM_001545 2.5 50.08 18.64 2.69 43 IGF2R NM_000876 2.5 58.76 15.43 3.81 44 IRS2 NM_003749 2.5 72.71 28.46 2.55 45 ITGB5 NM_002213 2 53.73 23.28 2.31 46 KIF18A NM_031217 2 50.87 21.92 2.32 47 LATS1 NM_004690 2 81.03 40.38 2.01 48 LIMK2 NM_005569 2 75.57 41.03 1.84 49 MAP2K3 NM_145110 2.5 56.31 16.88 3.34 50 MAP2K7 NM_145185 2.5 98.97 43.13 2.29 51 MAP3K13 NM_004721 2 74.85 29.33 2.55 52 MATK NM_139355 2 90.87 45.88 1.98 53 MCL1 NM_021960 2 94.93 52.15 1.82 54 MGC11266 NM_024322 2 56.20 23.98 2.34 55 MLCK NM_182493 2.5 52.37 13.23 3.96 56 MYLK NM_053025 2.5 89.77 13.70 6.55 57 MYO3B NM_138995 2.5 59.84 15.87 3.77 58 NEIL1 NM_024608 2 77.77 28.16 2.76 59 NEK2 NM_002497 2.5 62.97 27.57 2.28 60 NQO2 NM_000904 2 69.74 28.61 2.44 61 NR1H3 NM_005693 2 67.14 30.84 2.18 62 NTRK1 NM_002529 2 58.10 27.85 2.09 63 PAK6 NM_020168 2.5 64.80 20.78 3.12 64 PBK NM_018492 2 77.68 33.01 2.35 65 PCBD1 NM_000281 2.5 64.08 23.88 2.68 66 PDK1 NM_002610 2 69.99 29.57 2.37 67 PES1 NM_014303 2.5 51.38 14.28 3.60 68 P1K4CB NM_002651 2.5 58.97 25.54 2.31 69 PKN1 NM_002741 2 86.39 32.82 2.63 70 POLA NM_016937 2 61.21 23.89 2.56 71 POLH NM_006502 2.5 84.32 28.71 2.94 72 POLR2E NM_002695 2.5 77.27 31.46 2.46 73 POLR2I NM_006233 2 54.05 26.32 2.05 74 PRC1 NM_003981 2.5 60.94 15.68 3.89 75 PSMC2 NM_002803 2 60.43 27.13 2.23 76 PTP4A2 NM_003479 2 54.60 29.73 1.84 77 PTPN9 NM_002833 2 80.76 40.14 2.01 78 RAD21 NM_006265 2.5 62.63 16.73 3.74 79 RASGRF1 NM_002891 2.5 97.27 42.12 2.31 80 RASSF7 NM_003475 2.5 109.39 17.15 6.38 81 REV1L NM_016316 2.5 76.20 13.26 5.75 82 SCYL1 NM_020680 2 64.55 29.37 2.20 83 SDC4 NM_002999 2.5 70.19 21.12 3.32 84 SH3KBP1 NM_031892 2 61.19 27.82 2.20 85 SLC1A4 NM_003038 2 83.39 36.38 2.29 86 SLC25A26 NM_173471 2 62.05 34.62 1.79 87 SULF2 NM_018837 2.5 69.11 24.20 2.86 88 SULT1A2 NM_001054 2.5 70.56 22.63 3.12 89 SUV39H1 NM_003173 2.5 67.94 31.00 2.19 90 TIE1 NM_005424 2.5 74.99 23.57 3.18 91 TRIB1 NM_025195 2.5 57.34 17.24 3.33 92 TRIP13 NM_004237 2 71.01 40.01 1.77 93 TRRAP NM_003496 2.5 81.13 31.33 2.59 94 TXK NM_003328 2.5 96.42 15.71 6.14 95 UBE2I NM_003345 2.5 52.17 15.08 3.46 96 UIP1 NM_017518 2 66.20 24.65 2.69 97 WEE1 NM_003390 2 62.12 28.85 2.15 98 WEE2 AK131218 2 84.88 29.99 2.83 99 WNKI NM_018979 2 53.61 26.65 2.01 100 YES1 AF119914 2.5 68.36 22.16 3.08 101

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[0085] .sup.35 Lutz, W. et al., Conditional expression of N-myc in human neuroblastoma cells increases expression of alpha-prothymosin and ornithine decarboxy lase and accelerates progression into S-phase early after mitogenic stimulation of quiescent cells. Oncogene 13 (4), 803-812 (1996).

[0086] .sup.36 Grandori, C. el al., Werner syndrome protein limits MYC-induced cellular senescence. Genes Dev 17 (13), 1569-1574 (2003).

[0087] .sup.37 Cowling, V. H. & Cole, M. D., Turning the tables: Myc activates Wnt in breast cancer. Cell Cycle 6 (21), 2625-2627 (2007).

[0088] .sup.38 Kim, S. Y. et al., CKlepsilon is required for breast cancers dependent on beta-catenin activity. PLoS One 5 (2), e8979.

[0089] .sup.39 Firestein, R. et al., CDK8 is a colorectal cancer oncogene that regulates beta-catenin activity. Nature 455 (7212), 547-551 (2008).

[0090] .sup.40 Yang, W. S. & Stockwell, B. R., Inhibition of casein kinase 1-epsilon induces cancer-cell selective, PERIOD2-dependent growth arrest. Genome Biol 9 (6), R92 (2008).

[0091] .sup.41 Grandori, C., Mac, J., Siebelt, F., Ayer, D. E., & Eisenman, R. N., Myc-Max heterodimers activate a DEAD box gene and interact with multiple E box-related sites in vivo. EMBO Journal 15 (16), 4344-4357 (1996).

[0092] While certain embodiments of the invention have been illustrated and described, it will be appreciated that various changes can be made therein without departing from the spirit and scope of the invention.

Sequence CWU 1

1

10119068DNAHomo sapiens 1cggcgcgcgc gcggggcggg ggcgcgcgga ggggggggct gccccggggc ggccccccca 60ggtcggggcg cggcgggcgg cggcggcggg cgcgcgtccc gtccaggtcc ggagtaaccg 120ccgccgccgc cgccaaagct cgccaacatg gcggacctgg aggctgtgct ggccgatgtc 180agttacctga tggccatgga gaagagcaag gcgaccccgg ccgcccgcgc cagcaagagg 240atcgtcctgc cggagcccag tatccggagt gtgatgcaga agtaccttgc agagagaaat 300gaaataacct ttgacaagat tttcaatcag aaaattggtt tcttgctatt taaagatttt 360tgtttgaatg aaattaatga agctgtacct caggtgaagt tttatgaaga gataaaggaa 420tatgaaaaac ttgataatga ggaagaccgc ctttgcagaa gtcgacaaat ttatgatgcc 480tacatcatga aggaacttct ttcctgttca catcctttct caaagcaagc tgtagaacac 540gtacaaagtc atttatccaa gaaacaagtg acatcaactc tttttcagcc atacatagaa 600gaaatttgtg aaagccttcg aggtgacatt tttcaaaaat ttatggaaag tgacaagttc 660actagatttt gtcagtggaa aaacgttgaa ttaaatatcc atttgaccat gaatgagttc 720agtgtgcata ggattattgg acgaggagga ttcggggaag tttatggttg caggaaagca 780gacactggaa aaatgtatgc aatgaaatgc ttagataaga agaggatcaa aatgaaacaa 840ggagaaacat tagccttaaa tgaaagaatc atgttgtctc ttgtcagcac aggagactgt 900cctttcattg tatgtatgac ctatgccttc cataccccag ataaactctg cttcatcctg 960gatctgatga acgggggcga tttgcactac cacctttcac aacacggtgt gttctctgag 1020aaggagatgc ggttttatgc cactgaaatc attctgggtc tggaacacat gcacaatcgg 1080tttgttgtct acagagattt gaagccagca aatattctct tggatgaaca tggacacgca 1140agaatatcag atcttggtct tgcctgcgat ttttccaaaa agaagcctca tgcgagtgtt 1200ggcacccatg ggtacatggc tcccgaggtg ctgcagaagg ggacggccta tgacagcagt 1260gccgactggt tctccctggg ctgcatgctt ttcaaacttc tgagaggtca cagccctttc 1320agacaacata aaaccaaaga caagcatgaa attgaccgaa tgacactcac cgtgaatgtg 1380gaacttccag acaccttctc tcctgaactg aagtcccttt tggagggctt gcttcagcga 1440gacgttagca agcggctggg ctgtcacgga ggcggctcac aggaagtaaa agagcacagc 1500tttttcaaag gtgttgactg gcagcatgtc tacttacaaa agtacccacc acccttgatt 1560cctccccggg gagaagtcaa tgctgctgat gcctttgata ttggctcatt tgatgaagag 1620gataccaaag ggattaagct acttgattgc gaccaagaac tctacaagaa cttccctttg 1680gtcatctctg aacgctggca gcaagaagta acggaaacag tttatgaagc agtaaatgca 1740gacacagata aaatcgaggc caggaagaga gctaaaaata agcaacttgg ccacgaagaa 1800gattacgctc tggggaagga ctgtattatg cacgggtaca tgctgaaact gggaaaccca 1860tttctgactc agtggcagcg tcgctatttt tacctctttc caaatagact tgaatggaga 1920ggagagggag agtcccggca aaatttactg acaatggaac agattctctc tgtggaagaa 1980actcaaatta aagacaaaaa atgcattttg ttcagaataa aaggagggaa acaatttgtc 2040ttgcaatgtg agagtgatcc agagtttgtg cagtggaaga aagagttgaa cgaaaccttc 2100aaggaggccc agcggctatt gcgtcgtgcc ccgaagttcc tcaacaaacc tcggtcaggt 2160actgtggagc tcccaaagcc atccctctgt cacagaaaca gcaacggcct ctagcaccca 2220gaaacaggga gggtcctcga ggaggacaca ccagggtctc agccttttgg ggtgaacgag 2280gatgaggcat ctgatctatt cgctaccggg actcctccag gctcccgaga ggagtcggga 2340cccttcggct tggggtcagc tcagctccct gccttgtcac atttgtctgc attagaaact 2400actgaagaaa taaaagttct ttttctttgc tacacacttt ggtacctatg aacctagaac 2460ttgaagtgac tcctacttat cacgtaaatt tttatgtctg atatcaaaca catcttagac 2520tccccagaat ggaatttaaa gatgttcagt gttgggtaac agattgccct aagcattgcc 2580acatattctg tctagtcact gctgattttc tatgtctttg ctccatactg ctgggggatg 2640ggagagccac agtgtgtttc ttttgtgcac ttcgcaactg acttcttgtc ctggggttaa 2700aagttgaaga tattttctga tgatattaaa agttgaagat atttctgcac ttgggccctc 2760ctctgggagc cgcacccaca tgactgccct gcctctgacc agtctgttcc ggggccccct 2820cagccaggtg ggaatgacgg acacgtacta tccaagtgta tgggattaac taatcattga 2880aggcattcat ccgtccatca ttggaaagat ttacagtgat tctgaaggac aggccgtgga 2940gttttaggtt tcaggggcaa gagcagtttt caaaagtctt tgagtccagt gtgcacgagt 3000cgacaagcag tacctggcat gcaggagcac tcatgggtga gtccgtctca ggtctcgaca 3060attagcagtt gtgtgacagt cattctggtt ccttctgcct gaccctggga gacatatcag 3120taatggatgt acaaaagcag gtctgtttta tgtcttagta taatttcaga tgaattgtat 3180tgaaaaaatg ctgaggaatg aatgtgtcaa aatgggttaa ctgtgtatat tgactttcat 3240gtcgtcatgc atctgtcatg aatgaatgat actttgcact gggctgtacg acagtgagga 3300ccttagggca tgaagccttt ttcctggtcc cagcagcatc tgccctgtga agtttgtttt 3360ctcccactgc ctccaggccc cactgatacc cccaaataga tgctgggtta tgagaaccag 3420cgaaatcccc catgtcatca gtcttaaaaa aaaaatttta caaatccacg tatttgtccc 3480attcttggag tagttttagt gtatgtcttt acattaacta ctaacagtat aaataacttg 3540acatcgtaat tgtctgcatc ctgtccttga tatttttagc agttccaaat ctttgttttt 3600gtatttgttt gctgtgttca tgggcaaagt aagtactttt taatgcagtt attttgagag 3660tttggaagat aattaccaaa agggtccatt atttcataag agttactttg caaaaaaaaa 3720aatgtgggtt tttttttttg tctatctcaa ctactagttg gggtttaaat taacatacat 3780tttctactat ctgttatttc cagtgtggga ggagggatgt actacttaca tgcattctcc 3840ttatttaaaa aggaagaata gtattcaaat tctgttgaaa cacacacaca cacacacaca 3900cacacacaca cacactccag aagcagaaaa gccattgttc ttaaagagtg aatgtcttcc 3960cagccctggt taattatagc tgtgactgat gccgttcccg tctgcatctc aagctcatag 4020gttctcagca tgtgcagttg aggatgcgct gggcctcatg cctgttctag atctccagga 4080taaagggcct gctgttgact ccaccagggt ctgggcttag cgtctaatat ctcgtaccta 4140gggcgtgagc tgcacaaacg tgttcagaaa gattattcaa ctttcccata cttgttctaa 4200aattgagctg atccgcatct ctttcaaaaa ctagaatttc tgctctaaga atagaacata 4260aggctccact cccttttaga aaagatatat gaattggaaa atgctctgaa agtccttttg 4320cttcaaacaa aagtgtaaac ttttacactt ccccaactca catttgattt gtaatgatat 4380ggttgagaag tacatctaga tgtcatttat taaaagtgct ttgtaagact agattgagct 4440gtttctgagg gcggtcacca gttgtgttgg ggtctggttt gagtgccttc tgccaaaatg 4500ttgtgatgga ggtgtttctg cgaccagaca caggataccg ctgtgtctgc acccggttgc 4560ctgcatggcc agaggaaaag tcagttggat taaacatcat ggtatacttg gctgttgttt 4620ttttttaatt ttttaatttt ttgggatagg gcctcgctct gtcacccagg ctggagaaca 4680gtgggatgat catggctcac tgcagccttg aattcctagg ttcaagcaat cctcccacgt 4740cagcctcctg agtagctagg actacaggtg catgccacct ttcctggcta atttattttt 4800tgggtagaga tggggtcttg aactcttagg ctcaagtgat cctccttcct tggcctccca 4860aaatgctgga attagagatg taagccacca tgcccagcca tagtacttgg atgttttaga 4920aggttttcca agtattacat aattcctaga tgttcaccct tattacactc caactattaa 4980aaaggtcaaa attcagccta ttttttttca ttattttaga ttcctgtggt tgggatattt 5040taacattgat gagaaaaata attgaggttg atatttttac aaaatcatgc ggtaataagt 5100cttgatttca tgattcaaaa gaatcaataa agcctaaaaa taatagatta ctttaagctg 5160ctatgtaaga tatatatgga ataaattaaa aacctttgtg aattcaggtt tattattttt 5220aacctaaaac attctctttg gttcattcat cccctcatgt catgggggct cattggtttt 5280ccttctttgt catatttaag tatgattttt caacaaaact tctagaagtc agcttattat 5340gtcaccattc atgcaaagtg ctcatgcctc tgattggtcc attcactgac gtgacaattt 5400caggtcctat gtttaaaaag aaggggctgg ccgggcacga tggctcacgc ctataatccc 5460agcactttgg gaggccgaga ggggcggttc acgaggtcag gagattgaga ccatcctggt 5520tagcagagtg aaaccccgtc tctactaaaa atacaaataa aaattagccg ggcgtggtgg 5580cgggcgcctg tagtcccagc tacttgggag gctgaggcag gagaatggca tgaacccggg 5640aggcagagct tgcagtgagc cgagattgcg ccactgcact ccagcctggg cgacagagcg 5700agactctgtc tcaaaaaaaa aaaggagggg ggctaaatat ccagtgagat gcactgagga 5760aaggaagcat tttgctgaag acagcagcag caacaaacaa tggtctgttt gttgcaaaca 5820agatgtagct tgatttctgg tctgacatat gccatataca gatattagaa acgactgttt 5880gaaggccaca ctggtcatct acaaagtaat gtttaccaat tgacgacagg gatttaacta 5940gattaaaaag atcaaagtgt ggtttttctc tgctttttaa aatttcactc ggaatttgta 6000gctgggccaa ttcaacacat tttacttttc agtggaattg atttttctaa tgtttcagaa 6060ttttaacata tcaagaagaa aacaacgttc tcaaagtctg gcctctttag catgatgtaa 6120acctatagaa atgctttgaa atgtgctggt gtaagataag agttatcttg tatgatttaa 6180tcatatgcag tgttgtctca gttacgttca gggaaatgtt tctgtgtcat tcagagatgc 6240ttgatgaatt aacacctccc accctgagtg aggggttgac ttgttgggag atgatttggg 6300cttcactggg atctgtgaca ggtgggggct gggctgggtg tcacaaagag aatagtggta 6360gaaatcgggc gaaggaagaa agaagttact ggtaaaaatc attacaccat aaagcaccaa 6420ggaaataact gagttaaaat aggtgaagtt tcttttttcc cccctgtaac aggagagttt 6480tccttatgat aattattctg agacttggtc actttgtttt tgaatgtgga gctgctgaac 6540tcattcagaa gccatttgct gcctatcagg actttctgaa gaagttcttt tgcctctgcc 6600taccctctgg caccctccca tggaggcaca ggggacccag agctaaagca ttaccaggcc 6660atctccaaaa caccccgtgt gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt 6720gcactttgca gcccccgagg tggagaggca gtgtctggat cactgtgaat gcattgcccc 6780attggtcagt tggggacact gttacaaatc cactgaagtc ctggtaaaac tgtcaagagt 6840aacaggcctc ttctgttcta ccctgctcac ttccacggtg agttaccagc ctgggcaaca 6900cagcaagacc ccatctctac aaaaaaaatt tttttaagta attaaccgtt taaatttttt 6960cctaaagatt taacatgatt tttccctcct atgtaaagtt tactggagag acttgaatta 7020cttaaattca tgttaatatg attttttttt aatccaggtc acattttaac aaagtttatt 7080atgaaacaaa tgaaatttga actctaaaat ggtactcctt ggcttcctca agtcacaatg 7140aactttatat tttctttgtc cttaaggact aagatagttg ttttatttca gccgaatcac 7200agagataacc actcctgcag gcccccacag ctggcccaaa ggggctgtct ttctgacctg 7260gctgtgttag cactgattga gaaacgcagg ctcccaaatt ttaaattgcc tttattaaaa 7320acacaaacta cagaaaatgg gttaagagta tacgcatttc atcaaacaca tataggggaa 7380aaaatccttc aatttagagt taaataactc agctttgtat agtagagtta gcgctccagt 7440atctaacaat ctcagaatca tctctgaaaa ctggtaacta tgcttccatt tttaattttg 7500tcctaaatat cagatgtctt tgatgtaagg gtagggaatg gagaaatatt ttcaattgtg 7560tatttgtatt acaaagaact tgaaatttac tttcttagtt gattatatta aatgatgtat 7620atattatatg tggtttataa gctcaacact ggccattttt ttagttttat tgttaaatgg 7680tatttttcta tgtttaatta taatagatct ggctttttct ggatagcata aagatcactg 7740aactatatat atataagaaa caagagttct attttagcac aaaggcattt tatattattt 7800attgaatcca taagtttgtt ttcgtcaaaa acattccata ttatttctgc tcctttttat 7860ttgtatagtt tgttatttaa agaaatggca gtccttcctg ttcttaatac aataaaattg 7920aaataatgca cctagtaatg tggccgacat ctcttctcac caccatggac tgttttcaac 7980aacagttgat cttctggtct gtgctgagag gcgcatgcat gtctttcgtc acgtcgggca 8040gcacacctgc tgtgaaatac tgctttcatc tacctcttca gaaggcttct tgcttgttga 8100caagtaccgc aaaggcttta ttctggactg gctatctcat aaaaggattt ctgtaagact 8160ttgcagtgtc attccctcag aacctaggtt tgtttctaaa gccacggtat tgtccaggag 8220cccctgtgtg tggggcaggt agctatccct cccatgtcat tagtaatcct ttaggattta 8280aggtacaact ggacagcatc attccttccc cttattgtgc caaatcccca ccatcagcct 8340tgccattgcc ttaagatttg attattgcac ccaattacct aaccactaaa cagaaaggcc 8400accttcactc tttgaaaaag gcaagctgtg cttagaaaca ctgcttttaa gagtagcaca 8460tttgagtgtg actttttccc cccttcacta tttcaaaatg gttttgaaat ggggtcttaa 8520aggtaagcgc cctcatacat gactgaaact ttgtgagagg tcttatattt gaatggaccc 8580ttaatgattt atgtgaaata gaatgaagtc ctgtctctgt gagagaacgt gcctcctcac 8640tcatttgtct ctgtctgttt tcatagccat caatatagta acatatttac tatattcttg 8700aatacccttg aagaaagaaa tccgttttct attgtgcatt gctatacgaa gtgaagccag 8760taaactagat actgtaaatc tagatattgt acctagacaa aatatcattg gttctatctc 8820tttttgtatc tgttgtgcca gggaaggttt ataatccctt ctcagtatac actcactagt 8880gcacgtctga aatagtatcc cacgggagat gctgctccac gtctgaggtc acctgccctg 8940tgtggggcac accaccgtca gcaccaccgt ttttacagtt actttggagc tgctagactg 9000gttttctgtg ttggtaaatt gcctatataa atctgaataa aaaggatctg tacaaaaaaa 9060aaaaaaaa 906822408DNAHomo sapiens 2aaacaccgct ctggtcacca tggcaacagc gggatgccgc gaacggcttc tgggcggggc 60cggtccctcg gacgattgga cctagcttgg cgcggaatcc gtgaattgcc cgcggcccga 120gggtgcagct cccggactga ctggctctgc ccttccccat ggacgcctcc tctagcccgt 180ggaatccaac cccggctcct gtcagcagcc ctcccctgct gctccccatc cctgccatcg 240tcttcatcgc tgtgggcatc tatttgttgc tgctgggtct agtcctgctg actaggaact 300gcctgctggc ccagggctgc tgcgcggacg gtagctcccc ctgcaggaag caaggttcct 360ccgggccccc agactgctgc tggacctgtg cagaagcctg caactttcct ctgcctagcc 420cggcccactt cctggatgct tgctgccccc agcccaccag agctgactgg gcacctcgct 480gcccccgctg ctgcccactc tgcgactgtg cctgtacgtg ccagctcccc gactgccaga 540gcctcaactg tctctgcttc gagatcaagc tccgatgagg acccagggcc cctgccctct 600ggggagcggc cagcccccag ggcccatgtg ccctcctccc tgaagagcct ttccccacgc 660cactggaacc acagatggcc tgccgagcac ccaggcctgg gaactggaag tggcagcgca 720gggcctggct ccctgcaggg caggactctt ggccggctgg acggcagctc ctctggaggg 780ccagaaaaga gaggggctag tgctcgggca ggtgccctgg cttcccttcc cctccacacg 840tcaacgattc tatttgaagt tgggcagggg ggtggcgctg ctcaccacac acaagtgtta 900taggaggagt ctggcccttg agtaccgggt acgcaggggt gcctcaacca cactccgtcc 960acggactctc cgttatttta ggaggtccct ggccaaagat ttatttctct tgacaaccaa 1020gggcctccgt ctggatttcc aaggaagaat ttcctctgaa gcaccggaac ttgctactac 1080cagcaccatg ccctaccaat atccagcact gaccccggag cagaagaagg agctgtctga 1140catcgctcac cgcatcgtgg cacctggcaa gggcatcctg gctgcagatg agtccactgg 1200gagcattgcc aagcggctgc agtccattgg caccgagaac accgaggaga accggcgctt 1260ctaccgccag ctgctgctga cagctgacga ccgcgtgaac ccctgcattg ggggtgtcat 1320cctcttccat gagacactct accagaaggc ggatgatggg cgtcccttcc cccaagttat 1380caaatccaag ggcggtgttg tgggcatcaa ggtagacaag ggcgtggtcc ccctggcagg 1440gacaaatggc gagactacca cccaagggtt ggatgggctg tctgagcgct gtgcccagta 1500caagaaggac ggagctgact tcgccaagtg gcgttgtgtg ctgaagattg gggaacacac 1560cccctcagcc ctcgccatca tggaaaatgc caatgttctg gcccgttatg ccagtatctg 1620ccagcagaat ggcattgtgc ccatcgtgga gcctgagatc ctccctgatg gggaccatga 1680cttgaagcgc tgccagtatg tgaccgagaa ggtgctggct gctgtctaca aggctctgag 1740tgaccaccac atctacctgg aaggcacctt gctgaagccc aacatggtca ccccaggcca 1800tgcttgcact cagaagtttt ctcatgagga gattgccatg gcgaccgtca cagcgctgcg 1860ccgcacagtg ccccccgctg tcactgggat caccttcctg tctggaggcc agagtgagga 1920ggaggcgtcc atcaacctca atgccattaa caagtgcccc ctgctgaagc cctgggccct 1980gaccttctcc tacggccgag ccctgcaggc ctctgccctg aaggcctggg gcgggaagaa 2040ggagaacctg aaggctgcgc aggaggagta tgtcaagcga gccctggcca acagccttgc 2100ctgtcaagga aagtacactc cgagcggtca ggctggggct gctgccagcg agtccctctt 2160cgtctctaac cacgcctatt aagcggaggt gttcccaggc tgcccccaac actccaggcc 2220ctgccccctc ccactcttga agaggaggcc gcctcctcgg ggctccaggc tggcttgccc 2280gcgctctttc ttccctcgtg acagtggtgt gtggtgtcgt ctgtgaatgc taagtccatc 2340accctttccg gcacactgcc aaataaacag ctatttaagg gggagtcggc aaaaaaaaaa 2400aaaaaaaa 240835441DNAHomo sapiens 3aattcctact tcctgaaact gaagccgttt atgagaaaca gtgtgtttca gagaggctgt 60accagaatta actctgctca gagttagatt tgctggtctt aaagtacttt tcctctttaa 120gataaaagaa gttcttctaa atcaggaatg gattgaaatc taatgaaccg aaactttggg 180tacttcggcc ttcaaggggc tcctttattg agaatcaatg tcttctccta ggtaattgat 240caccctagac ccagggacac ccaattcatc gtaatcatca tgaataatca aaaagtggta 300gctgtgctac tgcaagagtg caagcaagtg ctggatcagc tcttgttgga agcgccagat 360gtgtcggaag aggacaagag cgaggaccag cgctgcagag ctttactccc cagcgagtta 420aggaccctga tccaggaggc aaaggaaatg aagtggccct tcgtgcctga aaagtggcag 480tacaaacaag ccgtgggccc agaggacaaa acaaacctga aggatgtgat tggcgccggg 540ttgcagcagt tactggcgtc cctgagggcc tccatcctcg ctcgggactg tgcggctgcg 600gcggctattg tgttcttggt ggaccggttc ctgtatgggc tcgacgtctc tggaaaactt 660ctgcaggtcg ccaaaggtct ccacaagttg cagccagcca cgccaattgc cccgcaggtg 720gttattcgcc aagcccgaat ctccgtgaac tcaggaaaac ttttaaaagc agagtatatt 780ctgagcagtc taataagcaa caatggagca acgggtacct ggctgtacag aaatgaaagt 840gacaaggtcc tggtgcagtc ggtctgtata cagatcagag ggcagattct gcaaaagctg 900gggatgtggt acgaagcagc agagttaata tgggcctcca ttgtaggata tttggcactt 960cctcagccgg ataaaaaggg cctctccacg tcgctaggta tactggcaga catctttgtt 1020tccatgagca agaacgatta tgaaaagttt aaaaacaatc cacaaattaa tttgagcctg 1080ctgaaggagt ttgaccacca tttgctgtcc gctgcagaag cctgcaagct ggcagctgcc 1140ttcagtgcct atacgccgct cttcgtgctc acagctgtga atatccgtgg cacgtgttta 1200ttgtcctaca gtagttcaaa tgactgtcct ccagaattga aaaacttaca tctgtgtgaa 1260gccaaagagg cctttgagat tggcctcctc accaagagag atgatgagcc tgttactgga 1320aaacaggagc ttcacagctt tgtcaaagct gctttcggtc tcaccacagt gcacagaagg 1380ctccatgggg agacagggac ggtccatgca gcaagtcagc tctgtaagga agcaatgggg 1440aagctgtaca atttcagcac ttcctccaga agtcaggaca gagaagctct gtctcaagaa 1500gttatgtctg tgattgccca ggtgaaggaa catttacaag ttcaaagctt ctcaaatgta 1560gatgacagat cttatgttcc cgagagtttc gagtgcaggt tggataaact tatcttgcat 1620gggcaagggg atttccaaaa aatccttgac acctattcac agcaccatac ttcggtgtgt 1680gaagtatttg aaagtgattg tggaaacaac aaaaatgaac agaaagatgc aaaaacagga 1740gtctgcatca ctgctctaaa aacagaaata aaaaacatag atactgtgag tactactcaa 1800gaaaagccac attgtcaaag agacacagga atatcttcct ccctaatggg taagaatgtt 1860cagagggaac tcagaagggg aggaaggaga aactggaccc attctgatgc atttcgagtc 1920tccttggatc aagatgtgga gactgagact gagccatcgg actacagcaa tggtgaggga 1980gctgttttca acaagtctct gagtggcagc cagacttcca gtgcttggag caacttatca 2040gggtttagtt cctctgcaag ctgggaggaa gtgaattatc acgttgacga caggtcagcc 2100agaaaagagc ctggcaaaga acatctggtg gacactcagt gttccactgc cttgtctgag 2160gagctagaga atgacaggga aggcagagct atgcattcat tgcattcaca gcttcatgat 2220ctctctcttc aggaacccaa caatgacaat ttggagcctt ctcaaaatca gccacagcaa 2280cagatgccct tgacaccctt ctcgcctcat aataccccag gcattttctt ggcccctggt 2340gcagggcttc tagaaggagc tccagaaggt atccaggaag tcagaaatat gggacccaga 2400aatacttctg ctcactccag accctcatat cgttctgctt cttggtcttc tgattctggt 2460aggcccaaga atatgggcac acatccttca gtccaaaaag aagaagcctt tgaaataatt 2520gttgagtttc cagaaaccaa ctgcgatgtc aaagacaggc aggggaaaga gcagggagaa 2580gaaattagtg aaagaggcgc aggccctaca tttaaagcta gtccctcctg ggttgaccca 2640gaaggagaaa cagcagaaag cactgaagat gcacccttag actttcacag ggtcctgcac 2700aattctctgg gaaacatttc catgctgcca tgtagctcct tcacccctaa ttggcctgtt 2760caaaatcctg actccagaaa aagtggtggc ccagtcgcag agcagggcat cgaccctgat 2820gcctccacag tggatgagga ggggcaactg ctcgacagca tggatgttcc ctgcacaaat 2880gggcacggct ctcatagact gtgcattctg agacagccgc ctggtcagag ggcggagacc 2940cccaattcct ctgtaagcgg taacatcctc ttccctgtcc tcagcgagga ctgcactacc 3000acagaggaag gaaatcagcc tggaaacatg ctaaactgca gccagaactc cagctcatcc 3060tcagtgtggt ggctgaaatc acctgcattt tccagtggtt cttctgaggg ggacagccct 3120tggtcctatc tgaattccag tgggagttct tgggtttcat tgccgggaaa gatgaggaaa 3180gagatccttg aggctcgcac cttgcaacct gatgactttg aaaagctgtt ggcaggagtg 3240aggcatgatt ggctgtttca gagactagag aatacggggg tttttaagcc cagtcaactc 3300caccgagcac atagtgctct tttgttaaaa tattcaaaaa aatctgaact gtggacggcc 3360caggaaacta ttgtctattt gggggactac ttgactgtga agaaaaaagg cagacaaaga

3420aatgcttttt gggttcatca tcttcatcaa gaagaaattc tggggaggta tgttgggaaa 3480gactataagg agcagaaggg gctctggcac cacttcactg atgtggagcg acagatgacc 3540gcacagcact atgtgacaga atttaacaag agactctatg aacaaaacat tcccacccag 3600atattctaca tcccatccac aatactactg attttagagg acaagacaat aaagggatgt 3660atcagtgtgg agccttacat actgggagaa tttgtaaaat tgtcaaataa cacgaaagtg 3720gtgaaaacag aatacaaagc cacagaatat ggcttggcct atggccattt ttcttatgag 3780ttttctaatc atagagatgt tgtggtcgat ttacaaggtt gggtaaccgg taatggaaaa 3840ggactcatct acctcacaga tccccagatt cactccgttg atcagaaagt tttcactacc 3900aattttggaa agagaggaat tttttacttc tttaataacc agcatgtgga atgtaatgaa 3960atctgccatc gtctttcttt gactagacct tcaatggaga aaccatgcac atagaatacg 4020gcacagtctg gtcctttggg gcttgggcag ggccgtgaca caggttctgg ccaatgattt 4080gcaagaggaa ttgatcagta tcactttaag tcctgcattt aattggcagc acaagatcct 4140gcagagcctc tttccctctg ccacagttat caagaatggg tcaggagacc gctgcttctg 4200ggcataagtc ctgcaaggaa agcaacatgg aaaacagccc caactcaccc atgagggatg 4260aaaagcactc ttgagaaagg catgtgttgt ttaagccatt gagattttag agctttttgt 4320cactatctgt caagactgat actactgggg cttttcctat tgatttggga gttctttaca 4380tattaaaaaa atgtgagcct ttgtgatacg aattcaattt gttttcctgt cttttgacat 4440ttgactttgc ataaaagttt atctgtgcat aattttatat gtagttgaat tcatcaatct 4500tttattttgt atggcttttt ggttatgtat aatacttaga tcctccttat actctgagtt 4560tctttctttt taattctcct gtatttcctt ctagtataat taaatctgta aaaagtaaga 4620tggaagagtg gtacagtttt ctttatccag tctgtccttg atgggcattt aggtagactg 4680gataaagaaa atgtggtaca tatacaccat ggaacactat gtgtattaat ccactctcac 4740actgctatga agagatacct gagactgggt aatttagaaa gaaaagaggt ttaattaact 4800cacagttcca catggctggg gagacctcag gaaacttaca atcatggcag aaggcacctc 4860ttcatagggt agcaggagag agaatgagtg ccagcagggg aaatgccaga tgcttataaa 4920gccatcagat cttgtgagaa ttcattcact ctcacgagaa cagcatggga aaaactgcct 4980caattacctc ctaccaggtc cttcccatga cacatgggaa ttatgggact acaattcgag 5040atgagatttg ggtggggaca caaagccaaa ccatatcaca atgtaaccat aaaaaagaat 5100gagatcatgt cctttgcagg gacatggata gagctggagg ccattatttt tagcaaacta 5160atgcaagaac agaaaactaa ataccacttg ttctcactta taggtgagag ctaagtgatg 5220agagtaggtg gacacataga gggaacaaca cacaccaggg cttatcagag ggtggacagt 5280gggaggaggg agaggatcag gaaaaataac taatgggtac taggctgaat acctgggtga 5340tgaagtaatt cgcacaacaa acccccatga cacaaacctg cacatgtacc cctgaactta 5400aaataaaagt aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa a 544143253DNAHomo sapiens 4ggccgttcgg agaccagccc cagcgtgcca ggaccgtttc cggggcctgg ccggggcgtt 60gccgcggggt cggggaccag cacgagtgct gagtcacgcc ccgcccggga gcgcctcggg 120tcagtaactc gggaagacga ccaagcggga gcgggagcgg gagcgggagc cggagcgaga 180gcgcgcgggc gcggccgaca gtgcctgatt tgagatgggg tcccaggtct cggtggaatc 240gggagctctg cacgtggtga ttgtgggtgg gggctttggc gggatcgcag cagccagcca 300gctgcaggcc ctgaacgtcc ccttcatgct ggtggacatg aaggactcct tccaccacaa 360tgtggctgct ctccgagcct ccgtggagac agggttcgcc aaaaagacat tcatttctta 420ctcggtgact ttcaaggaca acttccggca ggggctagta gtggggatag acctgaagaa 480ccagatggtg ctgctgcagg gtggcgaggc cctgcccttc tctcatctta tcctggccac 540gggcagcact gggcccttcc cgggcaagtt taatgaggtt tccagccagc aggccgctat 600ccaggcctat gaggacatgg tgaggcaggt ccagcgctca cggttcatcg tggtggtggg 660aggaggctcg gctggagtgg agatggcagc agagattaaa acagaatatc ctgagaaaga 720ggtcactctc attcactccc aagtggccct ggctgacaag gagctcctgc cctccgtccg 780gcaggaagtg aaggagatcc tcctccggaa gggcgtgcag ctgctgctga gtgagcgggt 840gagcaatctg gaggagctgc ctctcaatga gtatcgagag tacatcaaag tgcagacgga 900caaaggcaca gaggtggcca ccaacctggt gattctctgc accggcatca agatcaacag 960ctccgcctac cgcaaagcgt ttgagagcag actagccagc agtggtgctc tgagagtgaa 1020cgagcacctc caggtggagg gccacagcaa cgtctacgcc attggtgact gtgccgacgt 1080gaggacgccc aagatggcct atcttgccgg cctccacgcc aacatcgccg tggccaacat 1140cgtcaactct gtgaagcagc ggcctctcca ggcctacaag ccgggtgcac tgacgttcct 1200cctgtccatg gggagaaatg acggtgtggg ccaaatcagt ggcttctatg tgggccggct 1260catggttcgg ctgaccaaga gccgggacct gttcgtctct acgagctgga aaaccatgag 1320gcagtctcca ccttgatgga gaggccaggc gggagaacta ccgcagcagg tgggcgtacg 1380gactgcttgg cgcatggcac ccgcctggca agtgctagaa ctaatgctat tcttctggaa 1440taagatgcca atgatgtggt ggctagaaat gcaacttgta taaaacaaaa atgggagaga 1500gagaggtatt aaacaaatac cccccttaga ggatactttc tgggtttgga aggtgtgctt 1560gctgtggtac tgggtgagcg gctcatgtgt gctggctgca tggtgctggg gaggccacag 1620ccagcccttc ctctgcacct gcctcctctg ggatgtgcat gtgtgtgtac gtgcttgtgg 1680tcatgacgcg tgccatttag agctctcaga gcagggcaga ttgctgggct ctggtggcca 1740gtgtctgtct gtgagggcag gaaggagagc tgcacattga gaacaaagga gggacctgag 1800gtggagagag gcccagcacc ccaaatctct gccatcacac ggtcggggag cccatacatt 1860ctgcaacaac cagggacttc acaggagcct tgttttcaat ttgctaacag gtgcataatc 1920cctgtgctcc ttaagcctca tggccttcct acatttccac tttatttgtt tgtttgttta 1980tttatttttg agacagtctc gccctgtcac ccaggctgga gtgcagtggc acgatctcag 2040ctcactgcaa cctacgcctt ctgggttcac gtgattctct tgccttagcc tcccaagtag 2100ctgggactac aggcacgtgc caccatgcct ggctaatttt tgtatttttt aaatagagac 2160ggggtttcac tgtgttggcc aggctggtct cgaacacctg acctcaggtg atccattcgt 2220cttggcctct cgaagtgctg ggattccagg cgtgagccac tgcggccagc acatttccac 2280ttttagatcc tactccatac cacaggtttc atttaagaag aaagagctag ataaatgtgc 2340tcttctggtt accccaccct gacagagtgc atttttacac ggctagcagg ggttgagact 2400gcagcctggc ctgccagcca ttggaggtgt ttaaggaagg gcagataatg tgactctttg 2460cggggtgcca tctgcttacc cattagcgag cagagggggt ttctgcgggt gacccccagc 2520atatttctag gttacttatg ggcagatttg taagtgacaa aactccagct gatgctggga 2580atggggagag ggcccttgag ggactttgtg gttttgtgct tctggtttcc tggccaaccc 2640cagggtcact tgtctggagg cccagctggg cactaatgtc tgccaccgac tatgttacag 2700tgtataaatg attcctctat ttgggagaga tcttccaatc cagaggagcc cctcttggac 2760tgcctgggtt aaatctgcat agcagaagtg gttgatgagt tcatctgaag aaattcaggc 2820cccacctccc caccctgccc ctccctgctc ccttttgatg gtggcctctg ggtactcggg 2880cagagtcctt gggacaccag cctctctggg gttctcaggc catcccgttg gggctgtcgc 2940ccaggcctaa gtgagtcgtg tgcctctatt ggaggatggc tgttcccctg gtggttgcat 3000ccaagtatct gtctttcttt atggaccacg aagggaagcc caccttcctg gaggcaggac 3060cttcggccta agaaacacag gccctggtgc tatctgacct ggggtccagc gaggtgggaa 3120tcccagtgtg tgagcgacag gccttcttct attgacttac aatattctag aaggacctac 3180gtgtggggac acagttttcc aaactgagga aaatgttgca ataaaagaat atgttgtaag 3240aaagacaaaa aaa 325351961DNAHomo sapiens 5cgcgcgtcgg cgccggcgcc aaggggcggc ctctagccac accgagtccg ccgcggcgtc 60cagggtcggc agcaaccgca gccgagcccg agcgggtggc ggcgccatgg cgtgcgcggg 120gctgctcacc gtgtgcctgc tccggccgcc cgcgccccag ccccagcccc agaccccgcg 180gcacccccag ctcgcgcccg acccggggcc cgccggacac acgctcttcc aggacgtttt 240ccgcagagca gacaagaatg atgatgggaa gctctcattt gaggaattcc agaattactt 300tgccgatggg gttctcagcc tgggggagct gcaggaactg ttcagcggca ttgatgggca 360tctcaccgac aatttagaaa cagaaaaact gtgtgactac ttctcagagc acctgggtgt 420ctaccggccg gtgctggctg cattggaatc gctgaaccgt gcagtgctcg ctgccatgga 480tgccaccaag ctggagtacg agagggcctc caaagtggac cagtttgtga cgcgcttcct 540gctgcgggag acggtgagcc agctgcaagc ccttcagagc tcgctggagg gggcgtcaga 600taccctggag gcccaggccc atggctggcg gtcagatgca gagagcgtgg aggcgcagag 660caggctctgc ggcagccggc gggcaggacg ccgagccctg aggagtgtca gccggtcatc 720cacctggtcc cccggctctt ctgacacagg gcgcagctca gaggccgaga tgcagtggcg 780gctccaggtg aaccgcctcc aggagctcat cgaccagctc gagtgcaagg ccccccggct 840ggaacccctg cgtgaagagg acctggccaa ggggcctgac ttgcacatcc tcatggccca 900gaggcaggtc caggtggcag aggaaggcct gcaggacttc caccgagccc tgcgctgcta 960tgtggacttc acaggggccc agagccattg tctgcatgtg tccgcccaga agatgctgga 1020cggtgcctcc ttcaccctgt atgagttctg gcaggatgag gcctcctgga gaaggcacca 1080gcagtcgcct ggcagcaagg ccttccagcg catcctcatc gaccacctgc gggccccgga 1140caccctcacc actgtgttct tcccagcctc ctggtggata atgaataaca actgagccag 1200acctgcacac gccgagggcc ccgggaccct gcctgcctcc ctctggagcc ttctggactg 1260gccagcccag cgcaaagacc agggcttgtc tcctcctgga cttgggcctg gtggaagggc 1320tctcagccca gggatcaggg actgggctgc ttgctttcta tttattattg atttatttat 1380ccctgtattt tattgtttgt cacttcagcc tccaagctac tttggcttct gcctggctca 1440ggagacctgg attctggtcc ctgctgtccc tgcctggctg agcgacccag ggcaggtccc 1500gtccctgtct gggtgggcct caggccatct ggccgcctag cgagggtcct gctttcttcc 1560tgctgtcttg ggaccaggct tctgctcctc ctcagccagc ggcagaagca gggctgatgc 1620tcagggaccc cccaaccctc aaaccttgcc tccgaggctg ggcctgagct gggtgccccg 1680tcgccctccc aggccactag gctctgactc ttccagcacc catggatgtg ccagaggcct 1740ctgggttggt ttgcatgtca tttgcatatc gtttgcatgc cctcatccca cccattctca 1800gggcagtatg ggaagcccca aggtgacctg gccaagtagc aataatttgg gtccagggtc 1860acctattgcc cccagaggcc tctgaacccc aggctgggac cccagcacag aggcaataaa 1920ggcagtggtc ccttccaaaa aaaaaaaaaa aaaaaaaaaa a 1961610650DNAHomo sapiens 6atgcagaaag cccggggcac gcgaggcgag gatgcgggca cgagggcacc ccccagcccc 60ggagtgcccc cgaaaagggc caaggtgggg gccggcggcg gggctcctgt ggccgtggcc 120ggggcgccag tcttcctgcg gcccctgaag aacgcggcgg tgtgcgcggg cagcgacgtg 180cggctgcggg tggtggtgag cgggacgccc cagcccagcc tccgctggtt ccgggatggg 240cagctcctgc ccgcgccggc ccccgagccc agctgcctgt ggctgcggcg ctgcggggcg 300caggacgccg gcgtgtacag ctgcatggcc cagaacgagc ggggccgggc ctcctgcgag 360gcggtgctca cagtgctgga ggtcggagac tcagagacgg ctgaggatga catcagcgat 420gtgcagggaa cccagcgcct ggagcttcgg gatgacgggg ccttcagcac ccccacgggg 480ggttctgaca ccctggtggg cacctccctg gacacacccc cgacctccgt gacaggcacc 540tcagaggagc aagtgagctg gtggggcagc gggcagacgg tcctggagca ggaagcgggc 600agtgggggtg gcacccgccg cctcccgggc agcccaaggc aagcacaggc aaccggggcc 660gggccacggc acctgggggt ggagccgctg gtgcgggcat ctcgagctaa tctggtgggc 720gcaagctggg ggtcagagga tagcctttcc gtggccagtg acctgtacgg cagcgcattc 780agcctgtaca gaggacgggc gctctctatc cacgtcagcg tccctcagag cgggttgcgc 840agggaggagc ccgaccttca gcctcaactg gccagcgaag ccccacgccg ccctgcccag 900ccgcctcctt ccaaatccgc gctgctcccc ccaccgtccc ctcgggtcgg gaagcggtcc 960ccgccgggac ccccggccca gcccgcggcc acccccacgt cgccccaccg tcgcactcag 1020gagcctgtgc tgcccgagga caccaccacc gaagagaagc gagggaagaa gtccaagtcg 1080tccgggccct ccctggcggg caccgcggaa tcccgacccc agacgccact gagcgaggcc 1140tcaggccgcc tgtcggcgtt gggccgatcg cctaggctgg tgcgcgccgg ctcccgcatc 1200ctggacaagc tgcagttctt cgaggagcga cggcgcagcc tggagcgcag cgactcgccg 1260ccggcgcccc tgcggccctg ggtgcccctg cgcaaggccc gctctctgga gcagcccaag 1320tcggagcgcg gcgcaccgtg gggcaccccc ggggcctcgc aggaagaact gcgggcgcca 1380ggcagcgtgg ccgagcggcg ccgcctgttc cagcagaaag cggcctcgct ggacgagcgc 1440acgcgtcagc gcagcccggc ctcagacctc gagctgcgct tcgcccagga gctgggccgc 1500atccgccgct ccacgtcgcg ggaggagctg gtgcgctcgc acgagtccct gcgcgccacg 1560ctgcagcgtg ccccatcccc tcgagagccc ggcgagcccc cgctcttctc tcggccctcc 1620acccccaaga catcgcgggc cgtgagcccc gccgccgccc agccgccctc tccgagcagc 1680gcggagaagc cgggggacga gcctgggagg cccaggagcc gcgggccggc gggcaggaca 1740gagccggggg aaggcccgca gcaggaggtt aggcgtcggg accaattccc gctgacccgg 1800agcagagcca tccaggagtg caggagccct gtgccgcccc ccgccgccga tcccccagag 1860gccaggacga aagcaccccc cggtcggaag cgggagcccc cggcgcaggc cgtgcgcttc 1920ctgccctggg ccacgccggg cctggagggc gctgctgtac cccagacctt ggagaagaac 1980agggcggggc ctgaggcaga gaagaggctt cgcagagggc cggaggagga cggtccctgg 2040gggccctggg accgccgagg ggcccgcagc cagggcaaag gtcgccgggc ccggcccacc 2100tcccctgagc tcgagtcttc ggatgactcc tacgtgtccg ctggagaaga gcccctagag 2160gcccctgtgt ttgagatccc cctgcagaat gtggtggtgg caccaggggc agatgtgctg 2220ctcaagtgta tcatcactgc caaccccccg ccccaagtgt cctggcacaa ggatgggtca 2280gcgctgcgca gcgagggccg cctcctcctc cgggctgagg gtgagcggca caccctgctg 2340ctcagggagg ccagggcagc agatgccggg agctatatgg ccaccgccac caacgagctg 2400ggccaggcca cctgtgccgc ctcactgacc gtgagacccg gtgggtctac atcccctttc 2460agcagcccca tcacctccga cgaggaatac ctgagccccc cagaggagtt cccagagcct 2520ggggagacct ggccgcgaac ccccaccatg aagcccagtc ccagccagaa ccgccgttct 2580tctgacactg gctccaaggc accccccacc ttcaaggtct cacttatgga ccagtcagta 2640agagaaggcc aagatgtcat catgagcatc cgcgtgcagg gggagcccaa gcctgtggtc 2700tcctggctga gaaaccgcca gcccgtgcgc ccagaccagc ggcgctttgc ggaggaggct 2760gagggtgggc tgtgccggct gcggatcctg gctgcagagc gtggcgatgc tggtttctac 2820acttgcaaag cggtcaatga gtatggtgct cggcagtgcg aggcccgctt ggaggtccga 2880gcacaccctg aaagccggtc cctggccgtg ctggcccccc tgcaggacgt ggacgtgggg 2940gccggggaga tggcgctgtt tgagtgcctg gtggcggggc ccactgacgt ggaggtggat 3000tggctgtgcc gtggccgcct gctgcagcct gcactgctca aatgcaagat gcatttcgat 3060ggccgcaaat gcaagctgct acttacatct gtacatgagg acgacagtgg cgtctacacc 3120tgcaagctca gcacggccaa agatgagctg acctgcagtg cccggctgac cgtgcggccc 3180tcgttggcac ccctgttcac acggctgctg gaagatgtgg aggtgttgga gggccgagct 3240gcccgtttcg actgcaagat cagtggcacc ccgccccctg ttgttacctg gactcatttt 3300ggctgcccca tggaggagag tgagaacttg cggctgcggc aggacggggg tctgcactca 3360ctgcacattg cccatgtggg cagcgaggac gaggggctct atgcggtcag tgctgttaac 3420acccatggcc aggcccactg ctcagcccag ctgtatgtag aagagccccg gacagccgcc 3480tcaggcccca gctcgaagct ggagaagatg ccatccattc ccgaggagcc agagcagggt 3540gagctggagc ggctgtccat tcctgacttc ctgcggccac tgcaggacct ggaggtggga 3600ctggccaagg aggccatgct agagtgccag gtgaccggcc tgccctaccc caccatcagc 3660tggttccaca atggccaccg catccagagc agcgacgacc ggcgcatgac acagtacagg 3720gatgtccatc gcttggtgtt ccctgccgtg gggcctcagc acgccggtgt ctacaagagc 3780gtcattgcca acaagctggg caaagctgcc tgctatgccc acctgtatgt cacagatgtg 3840gtcccaggcc ctccagatgg cgccccgcag gtggtggctg tgacggggag gatggtcaca 3900ctcacatgga acccccccag gagtctggac atggccatcg acccggactc cctgacgtac 3960acagtgcagc accaggtgct gggctcggac cagtggacgg cactggtcac aggcctgcgg 4020gagccagggt gggcagccac agggctgcgt aagggggtcc agcacatctt ccgggtcctc 4080agcaccactg tcaagagcag cagcaagccc tcaccccctt ctgagcctgt gcagctgctg 4140gagcacggcc caaccctgga ggaggcccct gccatgctgg acaaaccaga catcgtgtat 4200gtggtggagg gacagcctgc cagcgtcacc gtcacattca accatgtgga ggcccaggtc 4260gtctggagga gctgccgagg ggccctccta gaggcacggg ccggtgtgta cgagctgagc 4320cagccagatg atgaccagta ctgtcttcgg atctgccggg tgagccgccg ggacatgggg 4380gccctcacct gcaccgcccg aaaccgtcac ggcacacaga cctgctcggt cacattggag 4440ctggcagagg cccctcggtt tgagtccatc atggaggacg tggaggtggg ggctggggaa 4500actgctcgct ttgcggtggt ggtcgaggga aaaccactgc cggacatcat gtggtacaag 4560gacgaggtgc tgctgaccga gagcagccat gtgagcttcg tgtacgagga gaatgagtgc 4620tccctggtgg tgctcagcac gggggcccag gatggaggcg tctacacctg caccgcccag 4680aacctggcgg gtgaggtctc ctgcaaagca gagttggctg tgcattcagc tcagacagct 4740atggaggtcg agggggtcgg ggaggatgag gaccatcgag gaaggagact cagcgacttt 4800tatgacatcc accaggagat cggcaggggt gctttctcct acttgcggcg catagtggag 4860cgtagctccg gcctggagtt tgcggccaag ttcatcccca gccaggccaa gccaaaggca 4920tcagcgcgtc gggaggcccg gctgctggcc aggctccagc acgactgtgt cctctacttc 4980catgaggcct tcgagaggcg ccggggactg gtcattgtca ccgagctctg cacagaggag 5040ctgctggagc gaatcgccag gaaacccacc gtgtgtgagt ctgagatccg ggcctatatg 5100cggcaggtgc tagagggaat acactacctg caccagagcc acgtgctgca cctcgatgtc 5160aagcctgaga acctgctggt gtgggatggt gctgcgggcg agcagcaggt gcggatctgt 5220gactttggga atgcccagga gctgactcca ggagagcccc agtactgcca gtatggcaca 5280cctgagtttg tagcacccga gattgtcaat cagagccccg tgtctggagt cactgacatc 5340tggcctgtgg gtgttgttgc cttcctctgt ctgacaggaa tctccccgtt tgttggggaa 5400aatgaccgga caacattgat gaacatccga aactacaacg tggccttcga ggagaccaca 5460ttcctgagcc tgagcaggga ggcccggggc ttcctcatca aagtgttggt gcaggaccgg 5520ctgagaccta ccgcagaaga gaccctagaa catccttggt tcaaaactca ggcaaagggc 5580gcagaggtga gcacggatca cctgaagcta ttcctctccc ggcggaggtg gcagcgctcc 5640cagatcagct acaaatgcca cctggtgctg cgccccatcc ccgagctgct gcgggccccc 5700ccagagcggg tgtgggtgac catgcccaga aggccacccc ccagtggggg gctctcatcc 5760tcctcggatt ctgaagagga agagctggaa gagctgccct cagtgccccg cccactgcag 5820cccgagttct ctggctcccg ggtgtccctc acagacattc ccactgagga tgaggccctg 5880gggaccccag agactggggc tgccaccccc atggactggc aggagcaggg aagggctccc 5940tctcaggacc aggaggctcc cagcccagag gccctcccct ccccaggcca ggagcccgca 6000gctggggcta gccccaggcg gggagagctc cgcaggggca gctcggctga gagcgccctg 6060ccccgggccg ggccgcggga gctgggccgg ggcctgcaca aggcggcgtc tgtggagctg 6120ccgcagcgcc ggagccccag cccgggagcc acccgcctgg cccggggagg cctgggtgag 6180ggcgagtatg cccagaggct gcaggccctg cgccagcggc tgctgcgggg aggccccgag 6240gatggcaagg tcagcggcct caggggtccc ctgctggaga gcctgggggg ccgtgctcgg 6300gacccccgga tggcacgagc tgcctccagc gaggcagcgc cccaccacca gcccccactc 6360gagaaccggg gcctgcaaaa gagcagcagc ttctcccagg gtgaggcgga gccccggggc 6420cggcaccgcc gagcgggggc gcccctcgag atccccgtgg ccaggcttgg ggcccgtagg 6480ctacaggagt ctccttccct gtctgccctc agcgaggccc agccatccag ccctgcacgg 6540cccagcgccc ccaaacccag tacccctaag tctgcagaac cttctgccac cacacctagt 6600gatgctccgc agccccccgc accccagcct gcccaagaca aggctccaga gcccaggcca 6660gaaccagtcc gagcctccaa gcctgcacca cccccccagg ccctgcaaac cctagcgctg 6720cccctcacac cctatgctca gatcattcag tccctccagc tgtcaggcca cgcccagggc 6780ccctcgcagg gccctgccgc gccgccttca gagcccaagc cccacgctgc tgtctttgcc 6840agggtggcct ccccacctcc gggagccccc gagaagcgcg tgccctcagc cgggggtccc 6900ccggtgctag ccgagaaagc ccgagttccc acggtgcccc ccaggccagg cagcagtctc 6960agtagcagca tcgaaaactt ggagtcggag gccgtgttcg aggccaagtt caagcgcagc 7020cgcgagtcgc ccctgtcgct ggggctgcgg ctgctgagcc gttcgcgctc ggaggagcgc 7080ggccccttcc gtggggccga ggaggaggat ggcatatacc ggcccagccc ggcggggacc 7140ccgctggagc tggtgcgacg gcctgagcgc tcacgctcgg tgcaggacct cagggctgtc 7200ggagagcctg gcctcgtccg ccgcctctcg ctgtcactgt cccagcggct gcggcggacc 7260cctcccgcgc agcgccaccc ggcctgggag gcccgcggcg gggacggaga gagctcggag 7320ggcgggagct cggcgcgggg ctccccggtg ctggcgatgc gcaggcggct gagcttcacc 7380ctggagcggc tgtccagccg attgcagcgc agtggcagca gcgaggactc ggggggcgcg 7440tcgggccgca gcacgccgct gttcggacgg cttcgcaggg ccacgtccga gggcgagagt 7500ctgcggcgcc ttggccttcc gcacaaccag ttggccgccc aggccggcgc caccacgcct 7560tccgccgagt ccctgggctc cgaggccagc gccacgtcgg gctcctcagc cccaggggaa 7620agccgaagcc ggctccgctg gggcttctct cggccgcgga aggacaaggg gttatcgcca

7680ccaaacctct ctgccagcgt ccaggaggag ttgggtcacc agtacgtgcg cagtgagtca 7740gacttccccc cagtcttcca catcaaactc aaggaccagg tgctgctgga gggggaggca 7800gccaccctgc tctgcctgcc agcggcctgc cctgcaccgc acatctcctg gatgaaagac 7860aagaagtcct tgaggtcaga gccctcagtg atcatcgtgt cctgcaaaga tgggcggcag 7920ctgctcagca tcccccgggc gggcaagcgg cacgccggtc tctatgagtg ctcggccacc 7980aacgtactgg gcagcatcac cagctcctgt accgtggctg tggcccgagt cccaggaaag 8040ctagctcctc cagaggtacc ccagacctac caggacacgg cgctggtgct gtggaagccg 8100ggagacagcc gggcaccttg cacgtatacg ctggagcggc gagtggatgg ggagtctgtg 8160tggcaccctg tgagctcagg catccccgac tgttactaca acgtgaccca cctgccagtt 8220ggcgtgactg tgaggttccg tgtggcctgt gccaaccgtg ctgggcaggg gcccttcagc 8280aactcttctg agaaggtctt tgtcaggggt actcaagatt cttcagctgt gccatctgct 8340gcccaccaag aggcccctgt cacctcaagg ccagccaggg cccggcctcc tgactctcct 8400acctcactgg ccccacccct agctcctgct gcccccacac ccccgtcagt cactgtcagc 8460ccctcatctc cccccacacc tcctagccag gccttgtcct cgctcaaggc tgtgggtcca 8520ccaccccaaa cccctccacg aagacacagg ggcctgcagg ctgcccggcc agcggagccc 8580accctaccca gtacccacgt caccccaagt gagcccaagc ctttcgtcct tgacactggg 8640accccgatcc cagcctccac tcctcaaggg gttaaaccag tgtcttcctc tactcctgtg 8700tatgtggtga cttcctttgt gtctgcacca ccagcccctg agcccccagc ccctgagccc 8760cctcctgagc ctaccaaggt gactgtgcag agcctcagcc cggccaagga ggtggtcagc 8820tcccctggga gcagtccccg aagctctccc aggcctgagg gtaccactct tcgacagggt 8880ccccctcaga aaccctacac cttcctggag gagaaagcca ggggccgctt tggtgttgtg 8940cgagcgtgcc gggagaatgc cacggggcga acgttcgtgg ccaagatcgt gccctatgct 9000gccgagggca agcggcgggt cctgcaggag tacgaggtgc tgcggaccct gcaccacgag 9060cggatcatgt ccctgcacga ggcctacatc acccctcggt acctcgtgct cattgctgag 9120agctgtggca accgggaact cctctgtggg ctcagtgaca ggttccggta ttctgaggat 9180gacgtggcca cttacatggt gcagctgcta caaggcctgg actacctcca cggccaccac 9240gtgctccacc tagacatcaa gccagacaac ctgctgctgg cccctgacaa tgccctcaag 9300attgtggact ttggcagtgc ccagccctac aacccccagg cccttaggcc ccttggccac 9360cgcacgggca cgctggagtt catggctccg gagatggtga agggagaacc catcggctct 9420gccacggaca tctggggagc gggtgtgctc acttacatta tgctcagtgg acgctccccg 9480ttctatgagc cagaccccca ggaaacggag gctcggattg tggggggccg ctttgatgcc 9540ttccagctgt accccaatac atcccagagc gccaccctct tcttgcgaaa ggttctctct 9600gtacatccct ggagccggcc ctccctgcag gactgcctgg cccacccatg gttgcaggac 9660gcctacctga tgaagctgcg ccgccagacg ctcaccttca ccaccaaccg gctcaaggag 9720ttcctgggcg agcagcggcg gcgccgggct gaggctgcca cccgccacaa ggtgctgctg 9780cgctcctacc ctggcggccc ctagaggcac ggaccacagc caggcctcgg gcttcaactg 9840gggttcccac caatgccacg ggacattcca gggcccacgc tgagccaggc gggcctgggg 9900cttcggttac caccagcagc aacatctggc tgggctctta cctcatagac cttcaaggac 9960agagacccca gggcctggac ctgatgccac cccaggccaa agccagagtg ggagacccat 10020tggtcaggct cagcagggtg ggaacaggca gagggacaag aggggaatgg agaagtggag 10080aggaaaagga atcgagggac aggaaggggg aggctctagg aaggttctgg gttgggggtc 10140agtgcatctc agggagaacc aaggaaggtg ggcatggctg gagaggagga aaaggaagga 10200gccccaggtg tcagggcagt aggctgggag tcagtgtggc aaagcggggg caggacacag 10260atacagtggc aggggcccag ggctgggaca tgagagaagg cagcgaggcg gcagagggag 10320aagagaggac tcaggtggag gtggggtggg tcagctgtca gcatccctca gaggagaaat 10380gtggagagct ggaggccagc agtcactcac actcgctctg tcctcctgtc cagtggatac 10440agccctgggc gctctgctgg cccaaggatg tccccactgc ccctccatgg cctctggcct 10500tcttcccatt catatttatt tatttattga cttttatgaa gtttcccctt ccatccgatc 10560cctactgccc atgttgtcct gaccatccct cccagccatc cagctgtctg tctgtctgcc 10620acaaggaaat aaaaatggca agcagcataa 1065079004DNAHomo sapiens 7ggcggcgccg tggggccgag gtgtcgcttc ctgacggggc ggcgcggacg gacgcggccg 60gtgccggccg ggacgccggg cccgcagcct agctcgccat ctcgctcacg ccgcccgccc 120gcggggccgt cagcccccgc cgggccgggg ccatgcagga gagccagacc aagagcatgt 180tcgtgtcccg ggccctggag aagatcctag ccgacaagga ggtgaagcgg ccccagcact 240cccagctgcg cagggcctgc caggtggcgc tcgatgaaat taaagcagaa atagaaaagc 300agaggcttgg cactgctgca ccaccaaagg caaacttcat tgaagctgac aagtattttc 360ttccattcga gctagcttgc cagtccaagt ccccaagggt agtcagcaca tcccttgact 420gcttgcagaa actcatcgca tacgggcaca tcactggcaa cgcccctgac agtggagccc 480ctgggaagcg gctgatcgac agaattgttg aaaccatttg cagttgtttt cagggccctc 540agactgatga aggggttcag ttacaaataa ttaaggctct tctgactgca gtgacttccc 600cacacattga aattcatgag ggtactatcc tgcagacagt gagaacatgt tacaatatct 660atttggccag caaaaatctc atcaatcaaa ccactgccaa ggctaccctt actcagatgc 720tgaacgtcat tttcacccgc atggaaaacc aagtgttgca ggaggccaga gaactggaaa 780aaccaatcca gtcaaaaccc cagtcccctg tgatccaagc tgcagcagta tccccaaagt 840tcgttcgttt gaagcacagt caggcacaaa gcaaaccaac aactcccgaa aaaacagatt 900taaccaacgg tgaacatgcc aggagtgatt ctggaaaagt aagcacagaa aatggagacg 960cacccagaga aagaggctca tcactgtcag ggactgatga cggagcccag gaggtggtga 1020aggacatctt ggaagatgta gtcacatctg ccattaaaga agcagcggaa aagcatggtc 1080tgacagaacc tgagagagtt ctaggtgaac tggagtgcca ggaatgtgct attcccccag 1140gagttgatga aaactcacag accaacggga tagccgatga caggcagtcc ttgtcgtcag 1200cagataatct ggaatcggat gcacaaggac atcaagtggc tgccaggttc tcccacgttc 1260tgcagaagga tgccttcctt gtgttccgct ccctgtgcaa gctgtccatg aaaccccttg 1320gtgaaggccc tccagaccca aaatcccatg agctgcgttc caaggtggtt tccctgcagc 1380tgctcctctc tgtgttgcaa aatgctggcc ccgtattcag gactcacgag atgttcatca 1440atgcaatcaa gcaatatctc tgtgtggcct tgtccaaaaa cggcgtctct tcagtgcctg 1500atgtctttga gctctctctt gccatttttc ttactcttct ttcaaacttt aaaatgcact 1560tgaaaatgca gatagaggtc tttttcaaag agattttcct gaacatttta gaaacatcaa 1620caagttcttt tgagcacagg tggatggtca ttcagactct gacgaggatc tgtgcagatg 1680cccagtgtgt tgtggatatt tatgtcaact acgactgtga tttaaatgct gctaacattt 1740ttgagcgcct tgtaaatgat ttatccaaaa ttgctcaggg aagaagtgga catgagctgg 1800gaatgacacc tctgcaggag ctcagcctga ggaagaaagg cctggagtgc ctcgtgtcca 1860ttctcaagtg catggtggag tggagcaaag acctgtatgt gaatcccaac caccagacca 1920gcctcggtca ggagaggctc acggatcagg aaatagggga tgggaaaggc cttgacatgg 1980caagacggtg tagtgtgacg tccatggagt ccacagtgtc ctcggggacc cagacaactg 2040ttcaggatga ccctgagcaa tttgaggtca tcaagcaaca aaaagaaatc attgaacacg 2100gcatcgagct gttcaacaag aaacccaaga gggggatcca gtttctccag gagcagggca 2160tgctgggaac gtcagttgaa gacatagccc aattcctgca ccaggaggag cgcctggatt 2220ccacccaagt aggcgatttt ctgggagata gcgcaaggtt caacaaggag gtgatgtatg 2280cctacgtgga ccaacttgac ttctgtgaaa aagaatttgt ctcagccctg cggacattcc 2340tagaaggttt ccgcctacct ggagaagccc aaaagattga ccgattaatg gagaagtttg 2400ccgcaagata catagaatgc aaccaagggc aaactctgtt tgctagtgct gacactgctt 2460atgtcctagc gtattcaatt attatgctga ctacagactt gcacagtcct caggtaaaaa 2520ataaaatgac gaaagagcag tatattaaaa tgaatcgggg tatcaatgat agtaaagatc 2580tgccagaaga gtatctctca agcatctatg aagagataga aggcaagaaa attgcaatga 2640aagaaacaaa agagctaacg attgcaacca aatctactaa gcagaatgta gctagtgaaa 2700agcagcggcg gctgctgtac aacttagaga tggagcaaat ggctaaaaca gccaaagctc 2760tgatggaggc tgtgagccat gccaaagccc cgtttaccag tgccactcac ctggaccatg 2820tccggccaat gttcaaactg gtgtggacgc cactattggc agcctacagc atcggactcc 2880agaactgtga tgacactgaa gtggcctcct tgtgtttgga aggcatccga tgtgcaatcc 2940gaatcgcctg catctttgga atgcagctgg aacgagatgc ctatgttcag gctcttgctc 3000gcttctccct actcacagcc agctccagca tcacagaaat gaagcagaaa aacatcgaca 3060ccattaagac gcttatcaca gtggctcaca ccgatggcaa ctaccttggg aattcctggc 3120atgagatctt gaaatgcatc agccagctgg agctcgctca gctgatagga accggtgtga 3180agacgcgcta cctgtctgga tctgggcgtg aaagagaagg gagcctgaag ggccacacat 3240tggcaggaga agagttcatg ggccttggcc tcggtaattt ggtgagtggc ggagtggata 3300aaagacagat ggccagcttc caagaatcgg ttggtgagac cagctcgcag agtgtggttg 3360tagctgtgga caggattttt actgggtcta ccagactgga tggaaatgca atagttgact 3420ttgtccgctg gctgtgtgct gtgtccatgg atgaactggc ttccccccac catcctcgca 3480tgttcagctt gcagaagatt gtggagatat catactacaa catgaatcgg atccgactac 3540agtggtctcg aatatggcat gtgattggag atcacttcaa taaggttggc tgcaacccta 3600atgaagatgt ggctatcttt gctgttgact cattaaggca actctccatg aagtttcttg 3660agaagggtga attagccaac ttccgtttcc agaaagattt tctgaggccc tttgagcata 3720ttatgaagaa aaacaggtct cccaccatcc gggacatggc gatccgctgc attgcccaga 3780tggtgaactc ccaggcggcc aacatccgct caggttggaa gaacatcttt gccgtgttcc 3840accaggcagc ctctgatcat gatgggaaca ttgtggagct ggccttccag accacttgcc 3900acattgtcac aactattttc cagcaccatt ttcctgcagc catcgattcc tttcaggatg 3960ctgtgaagtg cttatcagag ttcgcctgca acgccgcttt ccctgacacg agcatggaag 4020cgattcggct catccgcttc tgtggcaaat acgtctctga gaggcctcgg gtgctacaag 4080aatacacaag tgatgacatg aatgtagctc ctggtgacag agtctgggtc cgaggctggt 4140tccccatctt attcgaactc tcctgcatca ttaatagatg caagttagat gtacgaacaa 4200ggggactcac agtcatgttt gagatcatga agagctatgg ccacaccttt gaaaagcact 4260ggtggcagga cctgttcaga atcgtgtttc ggatttttga caatatgaaa ctccctgagc 4320aactgtcaga gaaatctgag tggatgacaa caacctgcaa tcacgcactt tatgctattt 4380gtgatgtttt tacccagttt tatgaagctt tgaatgaagt tcttctttct gatgtatttg 4440cacaattgca gtggtgtgtc aaacaagata atgaacagtt ggcgcgatca ggtacaaatt 4500gcttagaaaa cttagtaata tccaatggag agaaattcag tcctgaagtc tgggatgaaa 4560cctgcaactg tatgttggat attttcaaaa caaccatccc acatgttttg ctgacatgga 4620gacctgtagg aatggaggaa gattcatcag aaaagcattt ggatgtggat ctggaccgcc 4680agtctttaag cagcatagat aaaaatccct ctgagagggg acagagccag ctctctaacc 4740caacagatga cagctggaag ggtagaccat acgcaaatca gaaactgttt gccagcctcc 4800tcatcaagtg tgtggtccag ttggaattga tacagaccat tgacaacatt gtgttctacc 4860ctgcgacgag caaaaaggag gatgcagagc acatggttgc cgcccagcaa gacacgctgg 4920atgcagatat ccacatagag acggaggatc agggcatgta taagtacatg tcttcccagc 4980acctcttcaa gctgttggac tgtttgcagg aatcccattc attctcaaag gccttcaact 5040ccaattacga gcagcggact gtcctgtggc gagcaggttt taagggcaag tctaaaccca 5100atcttctaaa acaagaaacc agcagcctgg cctgttgttt gaggatcctg tttcgaatgt 5160atgttgatga gaaccgcagg gattcctggg aagaaataca gcagagactt ttaactgttt 5220gcagtgaagc tcttgcctat ttcatcactg tgaattctga gagccatcgg gaggcctgga 5280caagtctctt gttgttactt ctaactaaaa ccctcaaaat aaatgatgaa aagttcaaag 5340cacatgcttc aatgtactac ccctacttgt gtgaaattat gcagtttgac ctgatccctg 5400agctccgagc agttctgcgg aagttcttcc tacggatagg tgttgtgtat aagatatgga 5460taccagaaga gccatcacag gtaccagcag cactgtcacc agtgtggtag ccctggctgc 5520ccaggccagt gctgcagctc tgcagaatgt tcagcatgcc atttctgact ggcacatctc 5580gtgaagtttc atagaaacaa ggagttggca tcttggatct cagaatggcc tggaaacgga 5640tggcctctac gctgttccat cacagtctcc aactaaggct tatggtattt cattaaactg 5700ttgcataccc agttagcaca gtaggtgggg agtctgcttc atttctatca ttccattttt 5760ctgattaaac tgtcaaatct gtcattgcat atgccatcgt tttctagcaa aatcccatga 5820ttggctataa acgttttgta agaagtcact ctccttgaaa atactgaaca tagctgtata 5880ggtttgtgat tattagagaa tatgttaata aaacttcttg taacggctaa ctgccaccta 5940aaatatgctg ggttttctgt tgtttgagtg tgttagagaa atttgaatgt ttttgtcagt 6000tacgagtcag ccgtaattag attagtttaa ggacaggtca ggattagaga agagttgttt 6060ttgtgttttg ttaatgtctg agtgattttt aaagtatttt acaaaaagat attgaaaatt 6120tggttgaagg cagagtttag taattaagtt agaattaaga gttttgcgag gttaaaaaaa 6180tgtgcctcgt ggatctccct gttttagtaa catggagaga aaaagtctac acgaaaaagt 6240gaacaattta atgaagatga ttagccttcc ttgaaataag tatttgtgga tgggtgttaa 6300attaaaattt ccagaataca ctgtccatct cacacactct gaaatctaat atatgaagta 6360gtaatgaaaa tgaagtagta atttaaccag agttcattta tccttgaata aaccttttta 6420ttttcacctc agaaaagtga gtgtactggc agttagtgtc actgctttgc acagtcccca 6480ttaaaggacc ctccagagag ggacagtaac tgtgcatgag aagccgctcc cataagcctc 6540ctcagccaga tgtcatgggt ggaactggag ctgtgtcggg gccagcacag ctgaactgtg 6600acaatggcag gaggtggcat gtgcccagca cttccattaa tctgagccta ggagttgaat 6660tctttggcaa ggttggattc tgaggtcctt attatgttaa tgatggtgca atactctcac 6720ctgcagtaga actgagttct gctgcagctt gtgtaaaagt gggcagtaca caagtacgtc 6780ccaaagcctg tgagcagtat acgtggatgc tcacccatga gaaggagcac acacgcctca 6840ttctctgccc tcacccactg ctcacctaga gcatcgctga gcgttagaca aagtgttaca 6900cagaatgatt aaaactttca gacttctacc tatgctcttt agtcctgtaa attgggttgt 6960attgatgtca actctggtgc cttagaagtt agtagtttgg gaacctatct gtaaaatcag 7020atgttttttc tttgtagaga aggatttctg gtgcttttgc ttactaagag accgatattc 7080ttaagttgtt ttcttgtttt aacagccttg agaaatgttt ggttttggcc agcagaattc 7140ttgtctactt ttttctttcc caaaaagtgt tttttaattt ctctaccaaa gaaaaaatga 7200gcaggtttag gtttttacat gacttatata cattagataa aaggagctgt ataatttagc 7260aggaagggac tatgggagaa tactttactg tgagtggaaa atgttagcac atttgactgg 7320tttgccctgg aatccactgc acctttacac tgcaccatga aacctacact ccctggtatc 7380atagcgcgtc atcacctcaa caagtcagtc gtctccattg atatttgtac aaaaggtata 7440catggggaac acgtgttcat tcattaagtc catcttgcgt gcagctatat ccctgattgg 7500ttatttttcc tttccttctg aggttctcat gtcattttct tcatcggatg tgactaaaat 7560ttttctggtg tcttctgccc tctctttaat tttgcctctt gaggggtagc agatgtgtca 7620gtgcatttta ttacttgctg aaacattcag gcttacattt cttattagtt tagtatttta 7680aaagatttaa ttttctgaat gaggcatttg aattgtacca gcaatggact tttaaaaaat 7740tggatgtaaa accattcagg gtgatttttc ttgtcagtgg acagtgacga acagagattt 7800gaaatccctt acctccaata ataagccatt cagcctaaat tcatttttat gaataaatct 7860cttctttctc atggtaaatg tggcttgtgc cactcaaaca ctagtgaaag ggtatgtaca 7920accgcaacat caggccagga caccatttat ttaaccaagt aatggaggag agtgaaacat 7980tttccaaggc cttatttctt tttcagaatg ctttaagtgt tgattatatg tgctgggtct 8040ctagagaagt ttttatttgt tacaatactg ctgctttgag caattttgtt tctcttcatt 8100gtctgttagg gaaatcacca gctttggcat cttaacaaca aacagtggat gggtaatttt 8160tatttctgat acgcatcttt agagtcaaat atatcttttc cctgtactcc tcatgtacaa 8220ccaaagaaca tacattatga aaattgtatt ataatatctg gaaacacaac attttcctct 8280ggcaggtgac ttttgtacga aatgaaaaaa aaaaaacctg tatttttttt gttgttcttt 8340tgtgattaag gatatacatt tagtagtctt tgttattaaa ggaacctgct gataagtaca 8400agtgtgacca tctcattcaa atgtttgttg ttatgatgca aatggatatt ggtttcaata 8460gaagctggat ccttaatact gcattttctg aattctgttt taatatttgt gttaaagtag 8520acatagctga actcacatgg aatcctggag ttttgttatc agcagctttg cagtttggga 8580aacaaagaaa ccaaagctga gtgttttaaa gaatgaacat atctggaaat ccttgctctc 8640aaaacaaaac aatataatct atcaaaggtg ttttactcag tgttctaatt tttaaaaaat 8700tttatctgca tatttgcatc aaatatttat gtgtaaaatg tatgttttac ctccttaaaa 8760tgcctaaaag ttagttaata gttactttgg tttaacctat acacaatgat taagtgcatt 8820taatattggt aatttaatga aaaccattcc ttgcccaatg gatgtataaa tttttgaaag 8880aataagcaga attatataat atgaaatgct atgtaaagtt ttctatgtaa aaatattatg 8940tataatacta ttaaaatatc ccatgctttg atcaggtggt acatcaataa aattttaaaa 9000agta 900487230DNAHomo sapiens 8gaacccgttt cttttccttc cccagtgcgt ctttcctgcg tcgttccggc gcggcgggag 60cagagatctg cggccgtttg cagcttgcgg tagggaggcg tggtggtctg aagcctccga 120gcagccgcgg ccatggcgga tgtaaccgcc cgtagtctgc aatacgagta caaggcgaac 180tcgaatcttg tgctccaagc tgaccgttct ctcattgacc ggacccgccg ggatgaaccc 240acaggagagg tgctgtccct tgttgggaag ctggagggca cccgtatggg agacaaggct 300caacggacca aaccgcagat gcaggaggaa agaagagcca agcgaagaaa gcgtgatgag 360gaccggcatg acatcaacaa gatgaagggt tatactctgc tgtcggaggg cattgatgag 420atggtgggca tcatctacaa gcccaaaact aaagagactc gggagaccta tgaggtgcta 480ctcagcttca tccaggctgc tcttggggac cagccacgtg atatcctttg tggggcagct 540gatgaagttc tagctgttct aaagaatgaa aagctgcggg acaaggaaag gcgaaaggag 600attgacctgc tgctgggtca aacagatgat accagatacc atgtgctagt gaacctgggc 660aaaaagatca cagactatgg tggagataag gaaatccaaa atatggatga caacattgat 720gagacatacg gtgtgaatgt gcagtttgag tctgatgagg aggaaggtga tgaagacgta 780tacggggagg ttcgagaaga ggcatctgat gatgacatgg aaggggacga ggctgtcgtg 840cgctgcaccc tctcggctaa tctcgtagcc tcaggtgaac tgatgagttc caagaagaag 900gatttgcacc ctcgggatat tgatgcattt tggctgcagc ggcagctcag tcgtttctat 960gatgatgcca tcgtgtcgca gaagaaggca gatgaagtat tggagatttt gaagacggcc 1020agtgatgatc gggaatgtga aaatcagctg gttctgctgc ttggtttcaa cacctttgat 1080ttcattaaag tgttgcggca gcacaggatg atgattttat actgtacctt gctggccagt 1140gcacaaagtg aagctgaaaa ggaaaggatt atgggaaaga tggaagctga cccagagcta 1200tccaagttcc tctaccagct tcatgaaacc gagaaggagg atctgatccg agaggaaagg 1260tcccggagag agcgagtgcg tcagtctcga atggacacag atctggaaac catggatctc 1320gaccagggtg gagaggcact ggctccacgg caggttctgg acttggagga cctggttttt 1380acccaaggga gccactttat ggccaataaa cgctgtcagc ttcctgatgg atccttccgt 1440cgccagcgta agggctatga agaggtgcat gtgcctgctc tgaagcccaa gccctttggc 1500tcagaagaac aactgcttcc agtggaaaag ctgccaaagt atgcccaggc tgggtttgag 1560ggcttcaaaa cactgaatcg gatccagagt aagctctacc gtgctgccct tgagacggat 1620gagaatctgc tgctgtgtgc tcctactggt gctgggaaga ccaacgtggc cctgatgtgc 1680atgctccgag agattgggaa acacataaac atggacggca ccatcaatgt ggatgacttc 1740aagattatct acattgcccc catgcgctcc ttggtgcagg agatggtggg cagctttgga 1800aagcgcctgg ccacttatgg catcactgtt gctgaactga ctggggacca ccagctgtgc 1860aaagaagaga tcagtgccac tcagatcatc gtctgcaccc ccgagaagtg ggacatcatc 1920acccgcaagg gtggtgagcg cacctacacc cagctggtgc ggctcatcat tctggatgag 1980attcatcttc tccacgatga cagaggtcct gtcttagaag ctttagtggc cagggccatc 2040cgaaacattg agatgaccca agaggatgtc cgactcattg gtctcagtgc caccctaccc 2100aactatgaag atgtagccac ctttctacgt gttgaccctg ccaagggtct cttttacttt 2160gacaacagct tccgtccagt gcctctggaa cagacatatg tgggtatcac agagaaaaaa 2220gctatcaagc gtttccagat catgaatgaa atcgtctatg aaaaaatcat ggaacatgct 2280ggaaaaaatc aggtgctggt gtttgtccac tcccggaagg agactggaaa gacagccagg 2340gccatccggg acatgtgcct agaaaaggac actctgggtc tgtttctgag ggagggctca 2400gcctccacag aagtcctgcg aacagaagct gagcagtgca agaacctaga gctgaaggat 2460cttctgcctt atggctttgc tattcatcac gcaggcatga ccagggttga ccgaacactc 2520gtggaggatc tttttgctga taaacatatt caggttttag tttccacagc aactctagct 2580tggggtgtga atctccctgc acatacagtc atcatcaaag gcacccaggt gtacagtcca 2640gagaaggggc gttggacaga actgggagca ctggacattc tgcagatgct gggacgtgcc 2700ggaagacccc agtatgacac caagggtgaa ggcatactca tcacatctca tggggagcta 2760cagtactacc tgtccctcct caatcaacaa cttcctattg aaagccagat ggtttcaaag 2820cttcctgaca tgctcaatgc agaaatcgtg ctaggaaatg tccagaatgc caaggatgcg 2880gtgaactggc tgggctatgc ctacctctat atccgaatgc tgcgatcccc aaccctctat 2940ggcatctctc atgatgacct

caagggagat cccctgctgg accagcgccg actagatctg 3000gttcatacag ctgccctgat gctggacaag aacaatctgg tcaagtacga caagaagacg 3060ggcaacttcc aggtgacaga actgggccgt atagccagcc actactacat caccaatgat 3120acagtgcaga cttacaacca gctgctgaag cccaccctga gtgagattga gcttttcagg 3180gtcttctcat tgtcctctga gttcaagaac atcacagtga gagaggagga gaagctggag 3240ctgcagaagt tgctggagag ggtgcctatc cctgtaaagg agagcattga ggaacccagt 3300gctaagatca acgttcttct gcaagccttc atctcacagc tgaaattgga gggctttgca 3360ctgatggctg acatggtgta tgtcacacag tcggctggcc ggttgatgcg agcgatattt 3420gaaattgtcc tgaaccgagg ttgggcacag cttacagaca agaccctgaa cctctgcaag 3480atgatcgaca aacgcatgtg gcagtccatg tgtcctctgc gccagttccg gaaactccct 3540gaggaagtag tgaagaagat tgagaagaag aatttcccct ttgagcgtct gtacgacctg 3600aatcataatg agattgggga gcttatccgc atgccaaaga tggggaagac catccacaaa 3660tatgtccatc tgtttcccaa gttggagttg tcagtgcacc tgcagcctat cacacgctcc 3720accctgaagg tggagctgac catcacgcca gacttccagt gggatgaaaa ggtgcatggt 3780tcatccgagg ctttttggat tctggtggag gatgtggaca gcgaggtgat tctgcaccat 3840gagtattttc tcctcaaggc caagtacgcc caggacgagc acctcattac attcttcgtg 3900cctgtctttg aaccgctgcc ccctcagtac ttcatccgag tggtgtctga ccgctggctc 3960tcttgtgaga cccagctgcc tgtctccttc cggcacctga tcttgccgga gaagtacccc 4020cctccaaccg aacttttgga cctgcagccc ttgcccgtgt ctgctctgag aaacagtgcc 4080tttgagagtc tttaccaaga taaatttcct ttcttcaatc ccatccagac ccaggtgttt 4140aacactgtat acaacagtga cgacaacgtg tttgtggggg cccccacggg cagcgggaag 4200actatttgtg cagagtttgc catcctgcga atgctgctgc agagctcgga ggggcgctgt 4260gtgtacatca cccccatgga ggccctggca gagcaggtat acatggactg gtacgagaag 4320ttccaggaca ggctcaacaa gaaggtggta ctcctgacag gcgagaccag cacagacctg 4380aagctgctgg gcaaagggaa cattatcatc agcacccctg agaagtggga catactttcc 4440cggcgatgga agcagcgcaa gaacgtgcag aacatcaacc tcttcgtggt ggatgaggtc 4500caccttatcg ggggcgagaa tgggcctgtc ttagaagtga tctgctcccg aatgcgctac 4560atctcctccc agattgagcg gcccattcgc attgtggcac tcagctcttc gctctccaat 4620gccaaggatg tggcccactg gctgggctgc agtgccacct ccaccttcaa cttccatccc 4680aatgtgcgtc ccgtcccctt ggagctgcac atccagggct tcaacatcag ccatacacaa 4740acccgcctgc tctccatggc caagcctgtg taccatgcta tcaccaagca ctcgcccaag 4800aagcctgtca ttgtctttgt gccgtctcgc aagcagaccc gcctcactgc cattgacatc 4860ctcaccacct gtgcagcaga catccaacgg cagaggttct tgcactgcac cgagaaggat 4920ctgattccgt acctggagaa gctaagtgac agcacgctca aggaaacgct gctaaatggg 4980gtgggctacc tgcatgaggg gctcagcccc atggagcgac gcctggtgga gcagctcttc 5040agctcagggg ctatccaggt ggtggtggct tctcggagtc tctgctgggg catgaacgtg 5100gctgcccacc tggtaatcat catggatacc cagtactaca atggcaagat ccacgcctat 5160gtggattacc ccatctatga cgtgcttcag atggtgggcc acgccaaccg ccctttgcag 5220gacgatgagg ggcgctgtgt catcatgtgt cagggctcca agaaggattt cttcaagaag 5280ttcttatatg agccattgcc agtagaatct cacctggacc actgtatgca tgaccacttc 5340aatgctgaga tcgtcaccaa gaccattgag aacaagcagg atgctgtgga ctacctcacc 5400tggacctttc tgtaccgccg catgacacag aaccccaatt actacaacct gcagggcatc 5460tcccatcgtc acttgtcgga ccacttgtca gagctggtgg agcagaccct gagtgacctg 5520gagcagtcca agtgcatcag catcgaggac gagatggacg tggcgcctct gaacctaggc 5580atgatcgccg cctactatta catcaactac accaccattg agctcttcag catgtccctc 5640aatgccaaga ccaaggtgcg agggcttatc gagatcatct ccaatgcagc agagtatgag 5700aacattccca tccggcacca tgaagacaat ctcctgaggc agttggctca gaaggtcccc 5760cacaagctga ataaccctaa gttcaatgat ccgcacgtca agaccaacct gctcctgcag 5820gctcacttgt ctcgcatgca gctgagtgct gagttgcagt cagatacgga ggaaatcctt 5880agtaaggcaa tccggctcat ccaggcctgc gtggatgtcc tttccagcaa tgggtggctc 5940agccctgctc tggcagctat ggaactggcc cagatggtca cccaagccat gtggtccaag 6000gactcatacc tgaagcagct gccacacttc acctctgagc atatcaaacg ttgcacagac 6060aagggagtgg agagtgtttt cgacatcatg gagatggagg atgaagaacg gaacgcgttg 6120cttcagctga ctgacagcca gattgcagat gtggctcgct tttgtaaccg ctaccctaat 6180atcgaactat cttatgaggt ggtagataag gacagcatcc gcagtggcgg gccagttgtg 6240gtgctggtgc agctggagcg agaggaggaa gtcacaggcc ctgtcattgc gcctctcttc 6300ccgcagaaac gtgaagaggg ctggtgggtg gtgattggag atgccaagtc caatagcctc 6360atctccatca agaggctgac cttgcagcag aaggccaagg tgaagttgga ctttgtggcc 6420ccagccactg gtgcccacaa ctacactctg tacttcatga gtgacgctta catgggatgt 6480gaccaggagt acaaattcag cgtggatgtg aaagaagctg agacagacag tgattcagat 6540tgagtcctga ggcatttact tttgggtaaa ggagagttga gcctgaatta ggaatgtgta 6600cattgtagga atcctggttg tggggaccag gtctgtgggc ctcaggtctg gccagccagg 6660gctggtgctg tccccgccta cctccacttc ctttcccttg ctcactctgg atccagtgac 6720agcaggtgtc atgggtcaag cataaatcat atatagcatt ttcaggcatg ttcctggtag 6780ttcttttgag tctgacattc taataaaata atttgtagaa accatttgtc tttgtagtga 6840ttccaaatta aaagttttct ttctccaacc tgagggcacg gccaaaaaga tctggttatt 6900ttttagccag gaacgtgctt gttaatgagt atgtctggag gacagacctg ctcattaggt 6960gtgctgtccc ctgtagcctc gtgagtcagc ccagaggagg gtacatgcga ctgtggcctg 7020gcctcagtgg tacccacaca tcagcactac cacaagaacc aacactgagc ctcggaagct 7080agatcacagg ttaggggttt ctctagatgg gggttctgaa atttgcagtg tctgctcctg 7140ggaggcagca ccagaaaggg cactgaaatg tactagctgg atgtgaccca gtcttaataa 7200acaggttttc taatccagaa aaaaaaaaaa 723091005DNAHomo sapiens 9cagacgtccc tgcgcgtcgt cctcctcgcc ctccaggccg cccgcgccgc gccggagtcc 60gctgtccgcc agctacccgc ttcctgccgc ccgccgctgc catgctgccc gccgcgctgc 120tccgccgccc gggacttggc cgcctcgtcc gccacgcccg tgcctatgcc gaggccgccg 180ccgccccggc tgccgcctct ggccccaacc agatgtcctt caccttcgcc tctcccacgc 240aggtgttctt caacggtgcc aacgtccggc aggtggacgt gcccacgctg accggagcct 300tcggcatcct ggcggcccac gtgcccacgc tgcaggtcct gcggccgggg ctggtcgtgg 360tgcatgcaga ggacggcacc acctccaaat actttgtgag cagcggttcc atcgcagtga 420acgccgactc ttcggtgcag ttgttggccg aagaggccgt gacgctggac atgttggacc 480tgggggcagc caaggcaaac ttggagaagg cccaggcgga gctggtgggg acagctgacg 540aggccacgcg ggcagagatc cagatccgaa tcgaggccaa cgaggccctg gtgaaggccc 600tggagtaggc ggtgcgtacc cggtgtcccg aggcccggcc aggggctggg cagggatgcc 660aggtgggccc agccagctcc tggggtcccg gccacctggg gaagccgcgc ctgccaagga 720ggccaccaga gggcagtgca ggcttctgcc tgggccccag gccctgcctg tgttgaaagc 780tctggggact gggccaggga agctcctcct cagctttgag ctgtggctgc cacccatggg 840gctctccttc cgcctctcaa gatcccccca gcctgacggg ccgcttacca tcccctctgc 900cctgcagagc cagccgccaa ggttgacctc agcttcggag ccacctctgg atgaactgcc 960cccagccccc gccccattaa agacccggaa gcctgaaaaa aaaaa 1005103631DNAHomo sapiens 10gcggccgctg cagagattgg aatccgcctg ccgggcttgg cgaaggagaa gggaggaggc 60aggagcgagg agggaggagg gccaagggcg ggcaggaagg cttaggctcg gcgcgtccgt 120ccgcgcgcgg cgaagatcgc acggcccgat cgaggggcga ccgggtcggg gccgctgcac 180gccaagggcg aaggccgatt cgggccccac ttcgccccgg cggctcgccg cgcccacccg 240ctccgcgccg agggctggag gatgcgttcc ctggggtccg gacttatgaa aatatgcatc 300agtttaatac tgtcttggaa ttcatgagat ggaagcatag gtcaaagctg tttggagaaa 360atcagaagta cagttttatc tagccacatc ttggaggagt cgtaagaaag cagtgggagt 420tgaagtcatt gtcaagtgct tgcgatcttt tacaagaaaa tctcactgaa tgatagtcat 480ttaaattggt gaagtagcaa gaccaattat taaaggtgac agtacacagg aaacattaca 540attgaacaat gcctcagcta tacatttaca tcagattatt gggagcctat ttgttcatca 600tttctcgtgt tcaaggacag aatctggata gtatgcttca tggcactggg atgaaatcag 660actccgacca gaaaaagtca gaaaatggag taaccttagc accagaggat accttgcctt 720ttttaaagtg ctattgctca gggcactgtc cagatgatgc tattaataac acatgcataa 780ctaatggaca ttgctttgcc atcatagaag aagatgacca gggagaaacc acattagctt 840cagggtgtat gaaatatgaa ggatctgatt ttcagtgcaa agattctcca aaagcccagc 900tacgccggac aatagaatgt tgtcggacca atttatgtaa ccagtatttg caacccacac 960tgccccctgt tgtcataggt ccgttttttg atggcagcat tcgatggctg gttttgctca 1020tttctatggc tgtctgcata attgctatga tcatcttctc cagctgcttt tgttacaaac 1080attattgcaa gagcatctca agcagacgtc gttacaatcg tgatttggaa caggatgaag 1140catttattcc agttggagaa tcactaaaag accttattga ccagtcacaa agttctggta 1200gtgggtctgg actaccttta ttggttcagc gaactattgc caaacagatt cagatggtcc 1260ggcaagttgg taaaggccga tatggagaag tatggatggg caaatggcgt ggcgaaaaag 1320tggcggtgaa agtattcttt accactgaag aagccagctg gtttcgagaa acagaaatct 1380accaaactgt gctaatgcgc catgaaaaca tacttggttt catagcggca gacattaaag 1440gtacaggttc ctggactcag ctctatttga ttactgatta ccatgaaaat ggatctctct 1500atgacttcct gaaatgtgct acactggaca ccagagccct gcttaaattg gcttattcag 1560ctgcctgtgg tctgtgccac ctgcacacag aaatttatgg cacccaagga aagcccgcaa 1620ttgctcatcg agacctaaag agcaaaaaca tcctcatcaa gaaaaatggg agttgctgca 1680ttgctgacct gggccttgct gttaaattca acagtgacac aaatgaagtt gatgtgccct 1740tgaataccag ggtgggcacc aaacgctaca tggctcccga agtgctggac gaaagcctga 1800acaaaaacca cttccagccc tacatcatgg ctgacatcta cagcttcggc ctaatcattt 1860gggagatggc tcgtcgttgt atcacaggag ggatcgtgga agaataccaa ttgccatatt 1920acaacatggt accgagtgat ccgtcatacg aagatatgcg tgaggttgtg tgtgtcaaac 1980gtttgcggcc aattgtgtct aatcggtgga acagtgatga atgtctacga gcagttttga 2040agctaatgtc agaatgctgg gcccacaatc cagcctccag actcacagca ttgagaatta 2100agaagacgct tgccaagatg gttgaatccc aagatgtaaa aatctgatgg ttaaaccatc 2160ggaggagaaa ctctagactg caagaactgt ttttacccat ggcatgggtg gaattagagt 2220ggaataagga tgttaacttg gttctcagac tctttcttca ctacgtgttc acaggctgct 2280aatattaaac ctttcagtac tcttattagg atacaagctg ggaacttcta aacacttcat 2340tctttatata tggacagctt tattttaaat gtggtttttg atgccttttt ttaagtgggt 2400ttttatgaac tgcatcaaga cttcaatcct gattagtgtc tccagtcaag ctctgggtac 2460tgaattgcct gttcataaaa cggtgctttc tgtgaaagcc ttaagaagat aaatgagcgc 2520agcagagatg gagaaataga ctttgccttt tacctgagac attcagttcg tttgtattct 2580acctttgtaa aacagcctat agatgatgat gtgtttggga tactgcttat tttatgatag 2640tttgtcctgt gtccttagtg atgtgtgtgt gtctccatgc acatgcacgc cgggattcct 2700ctgctgccat ttgaattaga agaaaataat ttatatgcat gcacaggaag atattggtgg 2760ccggtggttt tgtgctttaa aaatgcaata tctgaccaag attcgccaat ctcatacaag 2820ccatttactt tgcaagtgag atagcttccc caccagcttt attttttaac atgaaagctg 2880atgccaaggc caaaagaagt ttaaagcatc tgtaaatttg gactgttttc cttcaaccac 2940catttttttt gtggttatta tttttgtcac ggaaagcatc ctctccaaag ttggagcttc 3000tattgccatg aaccatgctt acaaagaaag cacttcttat tgaagtgaat tcctgcattt 3060gatagcaatg taagtgccta taaccatgtt ctatattctt tattctcagt aacttttaaa 3120agggaagtta tttatatttt gtgtataatg tgctttattt gcaaatcacc cactccttta 3180caaccatact ttatatatgt acatacattc atactgtaga aaccagctca tgtgtacctc 3240atatcccatc cttaagagaa gaaatgttat aaagtagaac taaatataaa ttttcagaat 3300taatgcattc aaagtaatat atcaaatcca ggactttgtt aacttcaggt aaaaacttca 3360ttagggtaat atcatctcaa ttttttcaaa tgaaaggatt ctctaattag aaatttatat 3420gtcagagctg ttataaattt atcaactgtc aaatatgttc tggacagcta aatcatttga 3480gatttttggt tttttgattt ctattcccta acttgtgaag acaatgaaaa atcaggcaga 3540aatatttagt atctagtcag tatctgtagc tacactgtat aactgttctt caataaaatg 3600gttcatattt tatagaaaaa aaaaaaaaaa a 3631112533DNAHomo sapiens 11gggatgctgt gtgggtttca agaagacgcc acgcctccgc cgccgccacg cccccgccgc 60ctccaccgcc ggctgccgcg cccggaggag gtcgggatgt tatcacttcc gccggggctt 120ctcactgtgt ccgggtcagc tgctgccgcc gacgccgtac cgctgcggcc gggggattgg 180gccggggtct ccaccgccga ccgaggggag cgggctccgc tcggccctgc tttttgcgac 240ctggccgtca gccccacgtc gccggcctgg aggggcgaag aggacgaggg ggccaaggct 300tcctccgggg acattggctc cctggattat caagagtttg tagttgacat tgaatccagg 360ctgaggatgg aaggtgtgga acttaaagaa gaatggcaag atgaagattt tccgatacct 420ttaccagaag atgatagtat tgaagcagat atactagcta taactggacc agaggaccag 480cctggctcac tagaagttaa tggaaataaa gtgagaaaga aactaatggc tccagacatt 540agcctgacac tggatcctag tgatggctct gtattgtcag atgatttgga tgaaagtggg 600gagattgact tagatggctt agacacaccg tcagagaata gtaatgagtt tgagtgggaa 660gatgatcttc caaaacccaa gactactgaa gtaattagga aaggctcaat tactgaatac 720acagcagcag aggaaaaaga agatggacga cgctggcgta tgttcaggat tggagaacag 780gaccacaggg ttgatatgaa ggcaattgaa ccctataaaa aagttatcag ccatggggga 840tattatgggg atggattaaa tgccattgtt gtgtttgctg tctgtttcat gcctgaaagt 900agtcagccta actatagata cctgatggac aatcttttta aatatgttat tggcactttg 960gagctattag tagcagaaaa ctacatgata gtttatttaa atggtgcaac aactcgaaga 1020aaaatgccca gtctgggatg gctcaggaaa tgttatcagc aaattgatag aaggttacgg 1080aaaaatctaa aatccctaat cattgtacat ccttcttggt ttatcagaac acttctggct 1140gttacaagac catttattag ctcgaaattc agccaaaaaa ttagatacgt gtttaatttg 1200gcagaactag cagaacttgt ccccatggaa tacgttggca taccagaatg cataaaacaa 1260gttgatcaag aacttaatgg aaaacaagat gaaccgaaaa atgaacagta agtttggcat 1320ctagtccaaa caagactgaa gaatgtgctg atggagcagt gctgtttctg cattcataat 1380gcatttattg gcccatattt ttatgtaacc tgttacaaaa tagacttgac tttttcataa 1440tggacttttg tattatacaa gggactgttc actgctgtac tggtttgcaa atttcttgaa 1500tttagctctt taatagctaa ctgtattatt atcgttttat attttatatt gctaaataga 1560gaaccacact ttatataaag tagtttttgc atttgtttat tgaatgatgc atcttcttcg 1620gtgaaatatt tatatgcata aatggcaaag gaaagaaata atatatattt ttatgtcatt 1680gagcaatatt ttttaatgtg tacctgtctt atggaagaaa tatgcaggta tataagacca 1740cgattttcta aagtgcatat tagaattttt gtttttgtaa atggttaaat acatttcctg 1800ggtaacttag gaaattaagt ttttcataag gcaacagatg gttaaactga ttgtcatgaa 1860tacccaaaga tcatgtatat aatcgaagtg tattagtacc atcccaaggt ttttttctca 1920tttaacatat ttgtttcata attcagcaag tacagatgca agcgcattgc acactttttc 1980ctttctaaac ttaaagacaa gtcaaaaagc cattcttaga actagaggat ttaagagggt 2040aggaattagg gtttgtatat atgtatatat gggacatttt atcttctggc ccaaagtcag 2100aactttataa aaatcttgag tttgttcact aatgtgaaat aagctatgtg tccagggtat 2160tgctcccctg agtgtatatg agtgctgagt agtattgcag agaatgtgat gagttattca 2220ctgtcacaac tttttctata gaaaacaggg gctgcttttt aaactctcac tatgggcact 2280ttaccaaaat acttccatat caattatttg aactcggtag ttgtttgacc tagttagatg 2340tggtgtttat tcaagtttgt atgaaatcat gtttgacaat actgtaaatt aggttaattt 2400tgtaagtctt agcatcatca tattgtgctg ttttggataa cacgtttgtt acaagcattt 2460aaactgtttc atttggtagt acctttacat tgaaataaat tgtgtttgtg cctccaaaaa 2520aaaaaaaaaa aaa 2533122663DNAHomo sapiens 12gccccaagcc cagcctctcg ccagctggga gtcgcgcgct gcccacctcg ctgcccaggc 60ccccgacgcc gcggcaggag ccccccaaga gcgcgggaag ccccgtggac ctggcgctcc 120cggctcgggc gtggacgggg cgggcgccgg ggcggggcgc gcgtcctcgc gggtctgaat 180ggaagggtcg aggtcgtcgt cggcggcgag cagatcctga agccagaact ccaccccggc 240gcccgcgcca tgcggcggga gaggtgcggc gccccccacc cgcgtcgccg ccatggaggt 300gctgcggcgc tcctcggtct tcgccgccga gatcatggac gcctttgacc gctcgcccac 360agacaaggag ctggtggccc aggccaaggc gctgggccgg gagtacgtgc acgcgcggct 420gctgcgcgcc ggcctctcct ggagcgcgcc cgagcgtgcc gcgccggtcc cgggacgcct 480ggctgaggtg tgcgcggtgc tgctgcgcct gggcgatgag ctggagatga tccggcccag 540cgtctaccgc aacgtggcgc gtcagctgca catctccctg cagtctgagc ctgtggtgac 600cgatgcgttc ctggccgtgg ctggccacat cttctctgca ggcatcacgt ggggcaaggt 660ggtgtccctg tatgcggtgg ccgcggggct ggccgtggac tgtgtgaggc aggcccagcc 720tgccatggtc cacgccctcg tggactgcct gggggagttc gtgcgcaaga ccctggcaac 780ctggctgcgg agacgcggcg gatggactga tgtcctcaag tgtgtggtca gcacagaccc 840tggcctccgc tcccactggc tggtggctgc actctgcagc ttcggccgct tcctgaaggc 900tgccttcttc gtgctgctgc cagagagatg agctgcccac ctggcagtgg ccgcagcctg 960gccctctggg cccaacgcag gaggccctca gcacccgaac acatcttcct cctccccacc 1020cgagcctgga gcactctaac cctcggagac cccctaagcc ccgttcctcc gcagacccag 1080gccctccgga aggggtgagt ggggaggggc tttcctgagc ctggagctgg gctttggggc 1140agcctgcgac cctccccgct tgtgtccctt ctcctgtgat ctctgtgttt tcccttttct 1200ttctggggcc aggaagtcag ggtcaactcc caggcctcag atgcaggggc ccagaacacc 1260tgctctcacc tgagccccag gtgaaggggc ccgggaacac ctgctctcac ctgagcccca 1320ggtgaagggg cccgggaaca cctgctctca cctgaacccc aggtgaaggg gcccggaaca 1380cctgctctca cctgagcccc aggtgaaggg gcccggaaca cctgctctca cctgagcccc 1440aggtgaaggg gcccgggaac acctgctctc acctgagccc caggtgaagg ggcccgggaa 1500cacctgctct cacctgaacc ccaggtgaag gggcccagaa cacctgctct cacctgagcc 1560ccaggtgaag gggcccggaa cacctgctct cacctgagcc ccaggtgaag gggcccggga 1620acacctgctc tcacctgagc ccctggtgaa ggggcccgga acacttgctc tcacctgagc 1680cccaggtgaa ggggcccgga acacctgctc tcacctgagc ccccggtgaa ggggcccgga 1740acacttgctc tcacctgagc cccaggtgaa ggggcccgga acacctcctc tcacctgagc 1800cccaggtgaa ggggcccgga acacctcctg tcacctgagc cccaggtgaa ggggcccggg 1860aacacctctc acctgaaccc gggggtccca tcccaggaag aagggccatc tcaggacatg 1920agtcctcagg ggccctgcac attcaatctg aaggtgaccc tggcctggct gaagctggaa 1980gagctgtggg gactcagcct gtaaacagag cgtaaggttc acatgctggt tgcttaatcc 2040gtttctggag gaagagtatg acacccactt gtgatggggt ccttgtgcgg tggggaccgg 2100ggccggcggg ctccaggcca gcacacctaa cccatggatg tggaacctac ggccgagaag 2160gaatgttgca tgagtcggat cccagtccat tgtcagtgga gggtgagggt gaccccatct 2220gctatttttg tgctcatcct catacaacca tttggggatg tgcctattag ggctccgtaa 2280gaactcagat gcctgggaag cccagcccct caggtgcccc cacacacagc cttcccttga 2340cgcctacatt tctaggcaca tgtgaggcat ctttcctgga gccccgagcc agccctgtcc 2400ctccccagtg cagcatggca ctcaggagat acaggctgga catggggcag tcgttctggg 2460gaggcctggc ctagcagcca cccacctgag ccctcccggc caggcttcgt gctggggtgg 2520gccatgtgcc aggacaggag ggtcccggcg gaaagccagc cccggactca tcgtgacatt 2580gagatcccac tggagggtag gggtggtaat aaacttctcc aaacgatcgt tgtcatttta 2640gacagaaaaa aaaaaaaaaa aaa 2663134635DNAHomo sapiens 13attctttgga atactactgc tagaagtctg acttaagacc cagcttatgg gccacatggc 60acccagctgc ttctgcagag aaggcaggcc actgatgggt acagcaaagt gtggtgctgc 120tggccaagcc aaagacccgt gtaggatgac tgggcctctg ccccttgtgg gtgttgccac 180tgtgcttgag tgcctggtga agaatgtgat gggatcacta gcatgtctgc ggagagcggc 240cctgggacga gattgagaaa tctgccagta atgggggatg gactagaaac ttcccaaatg 300tctacaacac aggcccaggc ccaaccccag ccagccaacg cagccagcac caaccccccg 360cccccagaga cctccaaccc taacaagccc aagaggcaga ccaaccaact gcaatacctg 420ctcagagtgg tgctcaagac actatggaaa caccagtttg catggccttt ccagcagcct 480gtggatgccg tcaagctgaa cctccctgat tactataaga tcattaaaac gcctatggat 540atgggaacaa taaagaagcg cttggaaaac aactattact ggaatgctca ggaatgtatc 600caggacttca acactatgtt tacaaattgt tacatctaca acaagcctgg agatgacata 660gtcttaatgg cagaagctct ggaaaagctc ttcttgcaaa

aaataaatga gctacccaca 720gaagaaaccg agatcatgat agtccaggca aaaggaagag gacgtgggag gaaagaaaca 780gggacagcaa aacctggcgt ttccacggta ccaaacacaa ctcaagcatc gactcctccg 840cagacccaga cccctcagcc gaatcctcct cctgtgcagg ccacgcctca ccccttccct 900gccgtcaccc cggacctcat cgtccagacc cctgtcatga cagtggtgcc tccccagcca 960ctgcagacgc ccccgccagt gcccccccag ccacaacccc cacccgctcc agctccccag 1020cccgtacaga gccacccacc catcatcgcg gccaccccac agcctgtgaa gacaaagaag 1080ggagtgaaga ggaaagcaga caccaccacc cccaccacca ttgaccccat tcacgagcca 1140ccctcgctgc ccccggagcc caagaccacc aagctgggcc agcggcggga gagcagccgg 1200cctgtgaaac ctccaaagaa ggacgtgccc gactctcagc agcacccagc accagagaag 1260agcagcaagg tctcggagca gctcaagtgc tgcagcggca tcctcaagga gatgtttgcc 1320aagaagcacg ccgcctacgc ctggcccttc tacaagcctg tggacgtgga ggcactgggc 1380ctacacgact actgtgacat catcaagcac cccatggaca tgagcacaat caagtctaaa 1440ctggaggccc gtgagtaccg tgatgctcag gagtttggtg ctgacgtccg attgatgttc 1500tccaactgct ataagtacaa ccctcctgac catgaggtgg tggccatggc ccgcaagctc 1560caggatgtgt tcgaaatgcg ctttgccaag atgccggacg agcctgagga gccagtggtg 1620gccgtgtcct ccccggcagt gccccctccc accaaggttg tggccccgcc ctcatccagc 1680gacagcagca gcgatagctc ctcggacagt gacagttcga ctgatgactc tgaggaggag 1740cgagcccagc ggctggctga gctccaggag cagctcaaag ccgtgcacga gcagcttgca 1800gccctctctc agccccagca gaacaaacca aagaaaaagg agaaagacaa gaaggaaaag 1860aaaaaagaaa agcacaaaag gaaagaggaa gtggaagaga ataaaaaaag caaagccaag 1920gaacctcctc ctaaaaagac gaagaaaaat aatagcagca acagcaatgt gagcaagaag 1980gagccagcgc ccatgaagag caagccccct cccacgtatg agtcggagga agaggacaag 2040tgcaagccta tgtcctatga ggagaagcgg cagctcagct tggacatcaa caagctcccc 2100ggcgagaagc tgggccgcgt ggtgcacatc atccagtcac gggagccctc cctgaagaat 2160tccaaccccg acgagattga aatcgacttt gagaccctga agccgtccac actgcgtgag 2220ctggagcgct atgtcacctc ctgtttgcgg aagaaaagga aacctcaagc tgagaaagtt 2280gatgtgattg ccggctcctc caagatgaag ggcttctcgt cctcagagtc ggagagctcc 2340agtgagtcca gctcctctga cagcgaagac tccgaaacag gtcctgccta atcattggac 2400acggactctt aataaaacgg tcttcagttc cagattcctt cccagcaagc tatagcttaa 2460gtccattttc ttccgtgaaa gggacaggac tccatcaagt tatggaattc ctcagagccc 2520tgggcctgtc ccccggggtg gattagtcat gtccagcagc acacgcctag tcccgccttc 2580gggaaggctg cctgcctggc cagccgccca ggcctctctg tgtaaagact gcctggctgt 2640cctgcccagc cttcctggtt ctctggggtc ctctgggtgg gtggcatctc ctggagggtg 2700atgacaatcc ccaacacatg cattcatgtg gtgctactct gtgtgcaaag ccagacccca 2760agtatgtttt ctctctttgt cccatccctc tttttctggg actttggacc ctaactactt 2820ccctcctgaa ccttgcagtg acatcagtcc aggagagctc tcgttcagtg tgcggaagaa 2880cactctgacc tctagagctg tcctagataa ggagtgggag ctttagaggc aaggcctcta 2940gaccctggaa ggctcagtga ggctcttccc acagcatgct tctcactggt gccctgtaag 3000gctcgagcca ccgctgactc tgagcctttt ggagtctttc ctccttcgtc tccattgttc 3060ccgtgcattt ccaaaagctt aagttgcctg gtgggcattt ccccagtttc tttggcctcc 3120gtcttctcaa gtcacatagg gaaagtacct cctggaacca ggctgcagta tgcaggacct 3180gccaggcagg cactggtgaa gggccttggg cctatcatcc ccccaacccc acctcacccc 3240acccgcctcc tctagtgggg tgagtctggg ctggtggacc agagagggtg tcacagaccc 3300tcagggactg ccccatggac acctctgact ggtgttaaca gtgtgaacat tttccccgtc 3360ttcagtccct tagaatgacg acagcccctg gggttggggc aggcgagtgt ggccacatca 3420tccaagccct cccagagaca caaataggct tttttgctct aaaaataaat accagccctt 3480ttttggtcac aaatccagca tctcagcaga aaactgcctg acatgaaaag tcccctgagg 3540aactgcatct gcgtttcagg ggcttttcat tttttctcct tttttaaagt gtagattgtg 3600ggtgcttcct agaggcctgc cttcttctgg aactggaagt gggctatcac catgggcaag 3660cccttgggtg caggctcccc acctgcctgg gaactctggc agctctcctc agctccttgg 3720gcttgagcag ctgcaactgc cccagatttg ctgtggaagc aggggctagc cctggcctca 3780ccagggcctc ccggggccct gcattgatgc tcaggagttc ctgggctgct cttgatcctt 3840tctgggcatc cagcttccag ttaagctctg tttgccaaac aaactattct cagctgccct 3900ttggcctgcg cctgatgtgt tcctgttgca gtcccgcctg cctgagacag gagcaggcag 3960gagagccttc atgcccagat tcccacagga caattgggga gctgctggca ttgtctttct 4020gggaagattc tgctttcttg gaccaaatgg cagcctgatt accagtgtcg ggcctgcatg 4080ctgcccccga cacacgcacg cacgcgcaca cacgtgtgca catgggccat agccacaagc 4140cagctctcct ccagggtcct ttcaacctcg ctgtccaggg accctgtcct tcttgcccgt 4200ggggcttcca tctggcagag aacgttcagg gcttgttgaa cttgaaagct cattagactt 4260aagctgtcac ctgtgcttgg tgccccagga acagccagag aggacagtgc ccactcactt 4320cttgttggca gcctcctgtg caggaagtgc cagccgggcc tcgacgcacc agctggctgt 4380gggtcctgag gaggggcggg aggcggccgc tcagtgcaga tggggactcc tctcctctgc 4440cctgacctta ccctccatta cctccttcac tggagtgggg ctggggggtg ggtggaatca 4500gtgttttaat cggattttta aaaaacattt tatttctttg tacaattacc atcctatgta 4560aagatgaaat ttgtgttgag ttgaagattg tcatggaata aagatcacac cgtacttgag 4620gccatcttca tgtaa 4635142611DNAHomo sapiens 14aactgagtgg ctgtgaaagg gtggggtttg ctcagactgt ccttcctctc tggactgtaa 60gaatatgtct ccagggccag tgtctgctgc gatcgagtcc caccttccaa gtcctggcat 120ctcaatgcat ctgggaagct acctgcatta agtcaggact gagcacacag gtgaactcca 180gaaagaagaa gctatggccg cagtgattct ggagagcatc tttctgaagc gatcccaaca 240gaaaaagaaa acatcacctc taaacttcaa gaagcgcctg tttctcttga ccgtgcacaa 300actctcctac tatgagtatg actttgaacg tgggagaaga ggcagtaaga agggttcaat 360agatgttgag aagatcactt gtgttgaaac agtggttcct gaaaaaaatc ctcctccaga 420aagacagatt ccgagaagag gtgaagagtc cagtgaaatg gagcaaattt caatcattga 480aaggttccct tatcccttcc aggttgtata tgatgaaggg cctctctacg tcttctcccc 540aactgaagaa ctaaggaagc ggtggattca ccagctcaaa aacgtaatcc ggtacaacag 600tgatctggtt cagaaatatc acccttgctt ctggatcgat gggcagtatc tctgctgctc 660tcagacagcc aaaaatgcta tgggctgcca aattttggag aacaggaatg gaagcttaaa 720acctgggagt tctcaccgga agacaaaaaa gcctcttccc ccaacgcctg aggaggacca 780gatcttgaaa aagccactac cgcctgagcc agcagcagca ccagtctcca caagtgagct 840gaaaaaggtt gtggcccttt atgattacat gccaatgaat gcaaatgatc tacagctgcg 900gaagggtgat gaatatttta tcttggagga aagcaactta ccatggtgga gagcacgaga 960taaaaatggg caggaaggct acattcctag taactatgtc actgaagcag aagactccat 1020agaaatgtat gagtggtatt ccaaacacat gactcggagt caggctgagc aactgctaaa 1080gcaagagggg aaagaaggag gtttcattgt cagagactcc agcaaagctg gcaaatatac 1140agtgtctgtg tttgctaaat ccacagggga ccctcaaggg gtgatacgtc attatgttgt 1200gtgttccaca cctcagagcc agtattacct ggctgagaag caccttttca gcaccatccc 1260tgagctcatt aactaccatc agcacaactc tgcaggactc atatccaggc tcaaatatcc 1320agtgtctcaa caaaacaaga atgcaccttc cactgcaggc ctgggatacg gatcatggga 1380aattgatcca aaggacctga ccttcttgaa ggagctgggg actggacaat ttggggtagt 1440gaagtatggg aaatggagag gccagtacga cgtggccatc aagatgatca aagaaggctc 1500catgtctgaa gatgaattca ttgaagaagc caaagtcatg atgaatcttt cccatgagaa 1560gctggtgcag ttgtatggcg tctgcaccaa gcagcgcccc atcttcatca tcactgagta 1620catggccaat ggctgcctcc tgaactacct gagggagatg cgccaccgct tccagactca 1680gcagctgcta gagatgtgca aggatgtctg tgaagccatg gaatacctgg agtcaaagca 1740gttccttcac cgagacctgg cagctcgaaa ctgtttggta aacgatcaag gagttgttaa 1800agtatctgat ttcggcctgt ccaggtatgt cctggatgat gaatacacaa gctcagtagg 1860ctccaaattt ccagtccggt ggtccccacc ggaagtcctg atgtatagca agttcagcag 1920caaatctgac atttgggctt ttggggtttt gatgtgggaa atttactccc tggggaagat 1980gccatatgag agatttacta acagtgagac tgctgaacac attgcccaag gcctacgtct 2040ctacaggcct catctggctt cagagaaggt atataccatc atgtacagtt gctggcatga 2100gaaagcagat gagcgtccca ctttcaaaat tcttctgagc aatattctag atgtcatgga 2160tgaagaatcc tgagctcgcc aataagcttc ttggttctac ttctcttctc cacaagcccc 2220aatttcactt tctcagagga aatcccaagc ttaggagccc tggagccttt gtgctcccac 2280tcaatacaaa aaggcccctc tctacatctg ggaatgcacc tcttctttga ttccctggga 2340tagtggcttc tgagcaaagg ccaagaaatt attgtgcctg aaatttcccg agagaattaa 2400gacagactga atttgcgatg aaaatatttt ttaggaggga ggatgtaaat agccgcacaa 2460aggggtccaa cagctctttg agtaggcatt tggtagagct tgggggtgtg tgtgtggggg 2520tggaccgaat ttggcaagaa tgaaatggtg tcataaagat gggaggggag ggtgttttga 2580taaaataaaa ttactagaaa gcttgaaagt c 261115841DNAHomo sapiens 15cggctcgcgt gtagcggcgg cggcggcgtc tccgtgagga ggcgcgcggg gccatgacgt 60cagcgtccac aaaggtcgga gagatcttct cggcggccgg cgccgccttc acgaagctcg 120gggagctgac gatgcagctg catcccgtgg ccgactcttc tcctgcgggc gcgaagtgga 180cggagacgga aatagagatg ctgagggctg ctgtgaagcg atttggggac gatcttaatc 240acatcagctg tgtcatcaag gaacggacag tggcccagat aaaggccact gtgaaacgca 300aggtatatga agattctggc atcccccttc cagctgagtc acccaagaaa gggcccaaga 360aggtggcatc tggtgtcttg tcacctcctc cagctgcccc tcctcccagc agctccagtg 420tccctgaggc cgggggtccc cccataaaga aacagaaggc tgatgtgaca ctcagtgctc 480tgaacgactc cgatgccaac agtgacgtgg tggatattga agggctagga gaaactcctc 540cagctaagaa actcaacttc gaccaggcct gaccctggat tctggccttc tcatgacctc 600tgctgatcct cctctcctct cctgctgagc cttccacctc tgacctctca ctgttcatgc 660cggacctgtg gatctcctgg gactccgagc aaggcctgca cgagagaggg ctgaaaggct 720gctggggctg ccacctcgct attcccgcat aagcatctgc ccccaacccc tttgaccttc 780atctgatgga catttttata cagaaaacaa taaagatttc cctctcaaaa aaaaaaaaaa 840a 841161732DNAHomo sapiens 16cgcgaggcga gccgggcgcg gcggcagcag ggacgaccca ggctggagct gaggccgagc 60tgagggcgcc cgagcccccc gccccgcccg tcctctggct ccgcagcgct cagccccggg 120cccgcggaga catgaacgcc ccgcggcccc acgcaccccg ggcgcagcgg cccggccccg 180cggccccgtg atgggctcct gcgtgtcgcg agacctgttc acaagtgccc acaagaactg 240ccccatgccc cagggtgcgg accccttgaa cccagatctg ccctcgggcc gcactcccac 300cgtggctcca gactgtgtca ttggcaagga caaacagatg gatttctgtt gggatccttg 360gcagaggtgc ttccagacca ccaacggcta cctgtccgac tccagatccc gccccggcaa 420ctacaacgtg gcagccctgg ccacctcgtc ccttgtgggg gtggtgcaga gcatcaagga 480ccacatcaca aagcccacgg ccatggcccg aggccgcgtg gcccacctca tcgagtggaa 540gggctggagt gcccagccgg caggctggga gctgtcccca gctgaggacg agcattactg 600ctgcctcccg gatgagctgc gtgaggcccg ctttgctgca ggggtcgccg agcagtttgc 660catcacagag gccacactga gcgcttggtc ctcgctggac gaagaggagc tgcaccccga 720gaacagcccc caaggcatcg tccagctcca agatctggag agcatctacc ttcaggacag 780ccttcccagc ggcccctcac aggatgacag ccttcaggcc ttctcctcgc ccagcccctc 840ccctgacagc tgtccctcac ctgaggagcc ccccagcacc gctggcatcc cgcagccccc 900cagcccagag ctgcagcatc ggcggcggct gcccggggcc caaggacccg agggtgggac 960ccaccccccg ggctccctcc cctccatgga cagcggctcc ctctgggagg aggacgaggt 1020gttctataac tgaggtgggg gctgtgctgg tccagcacct gctctcacca tgacctcgcc 1080tggtgggcag cccaggcata tctggacccc ggggtccagg gcagggcatc ccttgacccc 1140tcgggtaggc acagggtagg tgcggcaggg atggggccag tgctcatggt ggcctctctg 1200tgcctcggtg gacctgcccc agcagtggga gccataaccc cctccccctt cattacttca 1260ctcaggtggg caccttcccc tgcagggtgt ctgccctcag ggaactcacg gactctcaga 1320gacaccaggg cagcctggcc cagaggagca acagccaggc ccccaggagg acagccatgg 1380agagaactga gacccactta cagtggggtc tgggaaccct gcctgtacct ggggttcagt 1440ccctcccaac tccctccttg tgtctgcccc ccagcaaagg tggggtgacc acttctggta 1500gctaagcacc tgctccccgg ctctcttcac ccaggacatc tgtctctctg gagtgtctgt 1560ctgtctgtcc ctccctctct gaacctgctt cctccgtgtc ccctgctcct cacccctggg 1620agcccactcc ccctccttgc ggctccctcc catctcactc aaggttctct gaggacatta 1680aagtggtgga ttcaccctgg aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aa 1732172507DNAHomo sapiens 17tggagcagct aatcctcaca gacctgtagg agctggagtg ggagctcaag caggattctt 60cccgagtccc tggcatcctc agaagcttca actctggagg caatgggtcg aaaggaagaa 120gatgactgca gttcctggaa gaaacagacc accaacatcc ggaaaacctt catttttatg 180gaagtgctgg gatcaggagc tttctcagaa gttttcctgg tgaagcaaag actgactggg 240aagctctttg ctctgaagtg catcaagaag tcacctgcct tccgggacag cagcctggag 300aatgagattg ctgtgttgaa aaagatcaag catgaaaaca ttgtgaccct ggaggacatc 360tatgagagca ccacccacta ctacctggtc atgcagcttg tttctggtgg ggagctcttt 420gaccggatcc tggagcgggg tgtctacaca gagaaggatg ccagtctggt gatccagcag 480gtcttgtcgg cagtgaaata cctacatgag aatggcatcg tccacagaga cttaaagccc 540gaaaacctgc tttaccttac ccctgaagag aactctaaga tcatgatcac tgactttggt 600ctgtccaaga tggaacagaa tggcatcatg tccactgcct gtgggacccc aggctacgtg 660gctccagaag tgctggccca gaaaccctac agcaaggctg tggattgctg gtccatcggc 720gtcatcacct acatattgct ctgtggatac cccccattct atgaagaaac ggagtctaag 780cttttcgaga agatcaagga gggctactat gagtttgagt ctccattctg ggatgacatt 840tctgagtcag ccaaggactt tatttgccac ttgcttgaga aggatccgaa cgagcggtac 900acctgtgaga aggccttgag tcatccctgg attgacggaa acacagccct ccaccgggac 960atctacccat cagtcagcct ccagatccag aagaactttg ctaagagcaa gtggaggcaa 1020gccttcaacg cagcagctgt ggtgcaccac atgaggaagc tacacatgaa cctgcacagc 1080ccgggcgtcc gcccagaggt ggagaacagg ccgcctgaaa ctcaagcctc agaaacctct 1140agacccagct cccctgagat caccatcacc gaggcacctg tcctggacca cagtgtagca 1200ctccctgccc tgacccaatt accctgccag catggccgcc ggcccactgc ccctggtggc 1260aggtccctca actgcctggt caatggctcc ctccacatca gcagcagcct ggtgcccatg 1320catcaggggt ccctggccgc cgggccctgt ggctgctgct ccagctgcct gaacattggg 1380agcaaaggaa agtcctccta ctgctctgag cccacactcc tcaaaaaggc caacaaaaaa 1440cagaacttca agtcggaggt catggtacca gttaaagcca gtggcagctc ccactgccgg 1500gcagggcaga ctggagtctg tctcattatg tgattcctgg agcctgtgcc tatgtcactg 1560caattttcag gagacatatt caactcctct gctcttccaa acctggtgtc tatccggcag 1620agggaggaag gcagagcaag tggagcaggg cttagcagga gcagtttctg gccagaagca 1680ccagcctgct gccagcgggg cagcccctca taggaggccc aggagggagc cccaaggcgt 1740agaagccttg ttgaagctgt gagcaggaga agcggtgccc accagcttcc aggtctccct 1800gacctgcctg ctctatgccc cacaccctac gtgccgtggc tctgtgcagt gtacgtagat 1860agctctcgcc tgggtctgtg ctgtttgtcg tgaaaagctt aatgggctgg ccaggctgtg 1920tcaccttctc caagcaaagc catatggagc atctacccag actcccactc tgcacacact 1980cactcccacc tctcaagcct ccaacctctt ggccagattg ggctcattaa tgtcgttgcc 2040tgcccatctg catgaatgac aggcagctcc ccatggtggt ctgcctgtga gctcttcaag 2100ttctaatcct taactccagg attagctccc aagtgcgctg agacccagcc agcacacttc 2160tggcccttct ccctgcctca atctaaaagc agtgccacac cctccaaagt ggaatagaaa 2220gaagttcatg agtaagggct gcaaggaatt cttatcctgg ccacatgtcc tccgtgcaca 2280cacccaatgg agttaacctt ggaagttgac tattttaatg tctgccagga gttctaatcc 2340tgcctctgtt cccttttctc tccttgaaag tccagcacac cattcttgtc cttccccagt 2400ttcctcgccc tccacccctc cagcttcatg ctcagtgttg tgcttaataa aatggacata 2460tttttctcta aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaa 2507185872DNAHomo sapiens 18aaaggaggga gtgcgagaga tccacgaagg gacaggcttg gagtcgctag agggaggtgt 60gggaccagcg aggagggggc ttcgccaggg agggggtgct ggcaggcgga gggagcggcg 120ggaggaggcg ccggaggagg agacggaggc ctggggacgg cagaagaggc ttcgcctgag 180ccgagcgctc tttctctcgc cgcgccgtct tgaagccgcg cgggctcgtg agcagcgcga 240ggccgccaag gtgcctcgct tcgccggagc cgctgccgcc cgccggaggg aagccggcct 300cgggcgcgca cgctcgtcgg agccccggcg cgccccgcgc ctgagcctgc tgacagcggc 360cgctgggctc aggctgtccg ctctgggctc cgcggcctcg gccccgctgc actccacctc 420cgccccctcg gactccctcc cctctgcttc tactcctcct gctccagtgc ggatcgtttc 480gcaactgctt gccactcgtc ccgtgcctgg ctgtttttcc atttcccggc cccctcttct 540tgagtacttt accccctgca tttggggaca gggactggaa aaggggcggg tggagcgtcc 600agtggagaag aaggaagcga ggcccgcagg aggaggagga tcggcggact gtggggagga 660gaccccacgc caccctttct ggtcatctcc cctcccgccc cgcccctgcg cacactccct 720cgcgggcgag ctactttcgg accaggaaag taagagcggc cctgggtgac agcgccgcgg 780ggccagtccc ggggttagcc gcgcgtctgc tcgcttctgg tccgtcgcgc tcccagccag 840ggcacagccc ggaccgagga tggcttcgac cacaacctgc accaggttca cggacgagta 900tcagcttttc gaggagcttg gaaagggggc attctcagtg gtgagaagat gtatgaaaat 960tcctactgga caagaatatg ctgccaaaat tatcaacacc aaaaagcttt ctgctaggga 1020tcatcagaaa ctagaaagag aagctagaat ctgccgtctt ttgaagcacc ctaatattgt 1080gcgacttcat gatagcatat cagaagaggg ctttcactac ttggtgtttg atttagttac 1140tggaggtgaa ctgtttgaag acatagtggc aagagaatac tacagtgaag ctgatgccag 1200tcattgtata cagcagattc tagaaagtgt taatcattgt cacctaaatg gcatagttca 1260cagggacctg aagcctgaga atttgctttt agctagcaaa tccaagggag cagctgtgaa 1320attggcagac tttggcttag ccatagaagt tcaaggggac cagcaggcgt ggtttggttt 1380tgctggcaca cctggatatc tttctccaga agttttacgt aaagatcctt atggaaagcc 1440agtggatatg tgggcatgtg gtgtcattct ctatattcta cttgtggggt atccaccctt 1500ctgggatgaa gaccaacaca gactctatca gcagatcaag gctggagctt atgattttcc 1560atcaccagaa tgggacacgg tgactcctga agccaaagac ctcatcaata aaatgcttac 1620tatcaaccct gccaaacgca tcacagcctc agaggcactg aagcacccat ggatctgtca 1680acgttctact gttgcttcca tgatgcacag acaggagact gtagactgct tgaagaaatt 1740taatgctaga agaaaactaa agggtgccat cttgacaact atgctggcta caaggaattt 1800ctcagcagcc aagagtttgt tgaagaaacc agatggagta aaggagtcaa ctgagagttc 1860aaatacaaca attgaggatg aagatgtgaa agcacgaaag caagagatta tcaaagtcac 1920tgaacaactg atcgaagcta tcaacaatgg ggactttgaa gcctacacaa aaatctgtga 1980cccaggcctt actgcttttg aacctgaagc tttgggtaat ttagtggaag ggatggattt 2040tcaccgattc tactttgaaa atgctttgtc caaaagcaat aaaccaatcc acactattat 2100tctaaaccct catgtacatc tggtagggga tgatgccgcc tgcatagcat atattaggct 2160cacacagtac atggatggca gtggaatgcc aaagacaatg cagtcagaag agactcgtgt 2220gtggcaccgc cgggatggaa agtggcagaa tgttcatttt catcgctcgg ggtcaccaac 2280agtacccatc aagccaccct gtattccaaa tgggaaagaa aacttctcag gaggcacctc 2340tttgtggcaa aacatctaag gcctgaaaac cattcacata tgggtcttct aaatttcaac 2400agtgccactt ctgcattctc tgttctcaag gcacctggat ggtgaccctg ggccgtcctc 2460tcctcctctt catgcatgtt tctgagtgca tgaagttgtg aaggtcctac atgtaatgca 2520tatgtgatgc atcatcttat catatattcc ttcctataca ttgtttacac ttcaactacg 2580gggatgttcc acacaaactt aaattactgt tggcaaaaca atagggggag attagacaaa 2640aaaaaaaatc cacaatattc caagtacaac tcttcatcaa gtttctctgt taatgccaag 2700atttaacaga cttaagaact attgttctct gaatgacagt tgtaagagaa atgtaaattt 2760tttagaactc tttgctgtta atctgttttg gtttgtttgg tttttttttt tttttttaag 2820gtaaaaaaaa aatacacctt cagtttcctg gtgtgatcct ggttaaaatg gatgattttt 2880cattgaaagt tttgctgatt aacaattaaa gtgggatgat atgtgggcaa aatcacttat 2940gaaagtagaa gcaagaatca gttggtttgc taccacataa agccatgctg tttttggtca 3000aactgtgtaa actggaaaaa ttcacatcat ttctgagttt aatcacttta ggatatattc 3060acattgtttt ggtgaatttg ctgaattgaa ttgtttttct ttctcaaatc tgtgatctct 3120tttctttatc ctgtttcttt gttcctttcg tttgctttct tatttttctt ttgttccatt

3180cttttcttac ttttttccct tttccttttt tggggaggct ggctagtagt gtgtgagaaa 3240agaatagaag tgaaatttgc ataatgaatg taaaagggaa ataaaagtct tttgaaggta 3300gctatactag cacttttgat catcttcagg gcccacaaaa atgttgtcaa gattttaaag 3360gtttataatt ctgcttaagc tctagtttgg acttaggtat cctaactatg ttggaggtat 3420ttgcattgtt taaagttagg ataaaagcaa gttcctcctg tgactgcaac gtcttactga 3480ttgggacagt tgccaggagg ataccaactt gatagcagag ggggttttat gcaaacgcac 3540tcacctccgc cttggggaat gaaagggtca cttctgcatc atcactagct agttttctag 3600tgttagagag gcttacaaat gtttgccatt ctcataagtg ttttgaactt gatctttgtg 3660acttgtgctt ttttagcttc tctcttgaat cagagtatca ttgtcttcct ccaaggagtt 3720agaatttccc agtttaaaac aaaaagggaa atgtcctagg ttttctttgt gcttctcatt 3780tttcctttgt tgattcaatt cctgtgattt ttgttctctt ccctgaagtg ctttacagtg 3840catggaatct ccatcattgt tattttaacg atagtaattc acagtcctca gaagcctatt 3900tttaaagcag aagcaaaaaa gaaaaacaaa ataacaaaaa caacccttcc tcttttctct 3960catctcacct ctctgtgttg attactaatc atcttagata ttattgctag tggatgtatg 4020gtagatgggt tgaagctttt ctgataatta ttacacaatt taaaacaaca tatatattta 4080aaataaatat atacagtaaa tatattgagc catgttaacc tgccaatgag atctgtgaaa 4140aaataatggc ctcatttttc tctttttaat ttcttttacc cttttgtgaa gcagctatac 4200gtggcataca tgtatttaaa gaaaaaaaaa tagatgtaga gtgttttttt tacactttta 4260acttagcatg tggtgttgaa gtattactgt agatcaagtt tgtcttccgc actaagatgt 4320gaggaaattg tgatttgttc tctccaccac aaatgaatta cacatttatt atcttctatc 4380attttgaaac actgcagttt accatgggac actgtatata tttcttgcca taatggtaaa 4440ggactgattg atatatttaa gagttaataa atttgtgatt tctgctgaca gtgcgtccat 4500ctttatttct tcagaagagg tactgtatgt atgcctgcat agtgctggcc agtgtcaagg 4560gcagtgtgtc ctactctggt ctcatttagt acataacaat ttgcacttgg tgagaatggc 4620aagttaattg ttctctgtga gcaaaacaat ggtctcttct gggaaaatgt tgctgagaac 4680aatatagtta acaactaaga ctcctaaaag cttctctaaa ctgtaccctc caatccagcc 4740ttcacatggc tgcttttttt tttttttttt aatacgaacc tgtccttgta acactttgat 4800gttatcattt ctgggataca ggcaagcacc ccagctcctg ctactcccca gcttgaactt 4860gagcatacat ggatgctcag cttcttttga tttgctaaaa acatcacact tgctcacatg 4920cctgtttatg ctgttcatgt tgtttatgtt tcttacctag aataaatagt ctcttcccct 4980acttcttttc ccgacttctt actttttcct aagattcagt gtacagcatc atgctccaca 5040gcaaaccttc ctaggcccta ttctgggctt gccttccctc tcaaaaccta cataatagat 5100tgtatttacc tctcctgtca accacattgt tttgaaaata tatttctatt tgtgtctcct 5160ctactgcagt ataatgtctc catgggcaag aactgtgtat tcatcattgc attcctaaac 5220ccaaaccaag gccaggaatg gagatatcat tgataaatag ttgttgaatt gaggccaagc 5280ccttttgata acagaagcct caaggggtac ccagatagtc cttgttttaa tgatgggttc 5340tctcaccact gtcttgatgc tctgagcaag ttacctcttc cctctgaccc tcagtttcca 5400tatttgtaaa atgagaataa acataccaac ttaataaaga tattgtgagg attaatgggt 5460acagagtgac tagaatgata tttgatagaa attaaatggt agcagtataa ctattctgat 5520cactgacatt aatattccta ttgttattat tctttgctca cgagggtata caactcttgt 5580tttgctgttg ggctgccctc tttatgtagg tttactgtta atgctgagga tatactcgga 5640ctcaaatgtc tcagcagaag gctgagagac accaaatgaa gtggtcatct agctgaatgt 5700aggaaaaatg aaatgtagta gcaaatcagt atattctaag gaaattttca aggaatatta 5760atcttcaccc aaattttgaa tttttatgta aaaaattata atttaagggt aaacatagat 5820gacacagctt tcgagtgatt tcattgaata aaattctact gacttctatg aa 5872193818DNAHomo sapiens 19ctccccggta aagtctcgcg gtgctgccgg gctcagcccc gtctcctcct cttgctccct 60cggccgggcg gcggtgactg tgcaccgacg tcggcgcggg ctgcaccgcc gcgtccgccc 120gcccgccagc atggccacca ccgccacctg cacccgtttc accgacgact accagctctt 180cgaggagctt ggcaagggtg ctttctctgt ggtccgcagg tgtgtgaaga aaacctccac 240gcaggagtac gcagcaaaaa tcatcaatac caagaagttg tctgcccggg atcaccagaa 300actagaacgt gaggctcgga tatgtcgact tctgaaacat ccaaacatcg tgcgcctcca 360tgacagtatt tctgaagaag ggtttcacta cctcgtgttt gaccttgtta ccggcgggga 420gctgtttgaa gacattgtgg ccagagagta ctacagtgaa gcagatgcca gccactgtat 480acatcagatt ctggagagtg ttaaccacat ccaccagcat gacatcgtcc acagggacct 540gaagcctgag aacctgctgc tggcgagtaa atgcaagggt gccgccgtca agctggctga 600ttttggccta gccatcgaag tacagggaga gcagcaggct tggtttggtt ttgctggcac 660cccaggttac ttgtcccctg aggtcttgag gaaagatccc tatggaaaac ctgtggatat 720ctgggcctgc ggggtcatcc tgtatatcct cctggtgggc tatcctccct tctgggatga 780ggatcagcac aagctgtatc agcagatcaa ggctggagcc tatgatttcc catcaccaga 840atgggacacg gtaactcctg aagccaagaa cttgatcaac cagatgctga ccataaaccc 900agcaaagcgc atcacggctg accaggctct caagcacccg tgggtctgtc aacgatccac 960ggtggcatcc atgatgcatc gtcaggagac tgtggagtgt ttgcgcaagt tcaatgcccg 1020gagaaaactg aagggtgcca tcctcacgac catgcttgtc tccaggaact tctcagctgc 1080caaaagccta ttgaacaaga agtcggatgg cggtgtcaag ccacagagca acaacaaaaa 1140cagtctcgta agcccagccc aagagcccgc gcccttgcag acggccatgg agccacaaac 1200cactgtggta cacaacgcta cagatgggat caagggctcc acagagagct gcaacaccac 1260cacagaagat gaggacctca aagctgcccc gctccgcact gggaatggca gctcggtgcc 1320tgaaggacgg agctcccggg acagaacagc cccctctgca ggcatgcagc cccagccttc 1380tctctgctcc tcagccatgc gaaaacagga gatcattaag attacagaac agctgattga 1440agccatcaac aatggggact ttgaggccta cacgaagatt tgtgatccag gcctcacttc 1500ctttgagcct gaggcccttg gtaacctcgt ggaggggatg gatttccata agttttactt 1560tgagaatctc ctgtccaaga acagcaagcc tatccatacc accatcctaa acccacacgt 1620ccacgtgatt ggggaggacg cagcgtgcat cgcctacatc cgcctcaccc agtacatcga 1680cgggcagggt cggcctcgca ccagccagtc agaagagacc cgggtctggc accgtcggga 1740tggcaagtgg ctcaatgtcc actatcactg ctcaggggcc cctgccgcac cgctgcagtg 1800agctcagcca caggggcttt aggagattcc agccggaggt ccaaccttcg cagccagtgg 1860ctctggaggg cctgagtgac agcggcagtc ctgtttgttt gaggtttaaa acaattcaat 1920tacaaaagcg gcagcagcca atgcacgccc ctgcatgcag ccctcccgcc cgcccttcgt 1980gtctgtctct gctgtaccga ggtgtttttt acatttaaga aaaaaaaaaa agaaaaaaag 2040attgtttaaa aaaaaaagga atccatacca tgatgcgttt taaaaccacc gacagccctt 2100gggttggcaa gaaggcagga gtatgtatga ggtccatcct ggcatgagca gtggctcacc 2160caccggcctt gaagaggtga gcttggcctc tctggtcccc atggacttag ggggaccagg 2220caagaactct gacagagctt tgggggccgt gatgtgattg cagctcctga ggtggcctgc 2280ttaccccagg tctaggaatg aacttctttg gaacttgcat aggcgcctag aatggggctg 2340atgagaacat cgtgaccatc agacctactt gggagagaac gcagagctcc cagcctgctg 2400tggaggcagc tgagaagtgg tggcctcagg actgagagcc cggacgttgc tgtactgtct 2460tgtttagtgt agaagggaag agaattggtg ctgcagaagt gtacccgcca tgaagccgat 2520gagaaacctc gtgttagtct gacatgcact cactcatcca tttctatagg atgcacaatg 2580catgtgggcc ctaatattga ggccttatcc ctgcagctag gagggggagg ggttgttgct 2640gctttgcttc gtgttttctt ctaacctggc aaggagagag ccaggccctg gtcagggctc 2700ccgtgccgcc tttggcggtt ctgtttctgt gctgatctgg accatctttg tcttgccttt 2760tcacggtagt ggtccccatg ctgaccctca tctgggcctg ggccctctgc caagtgcccc 2820tgtgggatgg gaggagtgag gcagtgggag aagaggtggt ggtcgtttct atgcattcag 2880gctgcctttg gggctgcctc ccttcttatt cttccttgct gcacgtccat ctcttttcct 2940gtctttgaga ttgacctgac tgctctggca agaagaagag gtgtccttac agaggcctct 3000ttactgacca actgaagtat agacttactg ctggacaatc tgcatgggca tcacccctcc 3060ccgcatgtaa cccaaaagag gtgtccagag ccaaggcttc taccttcatt gtccctctct 3120gtgctcaagg agttccattc caggaggaag agatctatac cctaagcaga tagcaaagaa 3180gataatggag gagcaattgg tcatggcctt ggtttccctc aaaacaacgc tgcagattta 3240tctgcacaaa catctccact tttgggggaa aggtgggtag attccagttc cctggactac 3300cttcaggagg cacgagagct gggagaagag gcaaagctac aggtttactt gggagccagc 3360tgagaagaga gcagactcac aggtgctggt gcttggattt agccaggctc ctccgagcac 3420ctcatgcatg tcccagcccc tgggccctag ccctttcctg ccctgcagtc tgcagtgcca 3480gcacgcaaat cccttcacca cagggtttcg ttttgctggc ttgaagacaa atggtcttag 3540aattcattga gacccatagc ttcatatggc tgctccagcc ccacttctta gcattcttac 3600tcctcttctg gggctaatgt cagcatctat agacaataga ctattaaaaa atcacctttt 3660aaacaagaaa cggaaggcat ttgatgcaga atttttgcat gacaacatag aaataattta 3720aaaatagtgt ttgttctgaa tgttggtaga cccttcatag ctttgttaca atgaaacctt 3780gaactgaaaa tatttaataa aataaccttt aaacagtc 3818201925DNAHomo sapiens 20aagatggccg cagtcggcaa ggagagacgt cgctgagggg cttgcctgaa gcgaggggat 60tctaacattt tcagagaacc ttttggaaag aacaagccta cttcaataaa tgaaggagaa 120taaagaaaat tcaagccctt cagtaacttc agcaaacctg gaccacacaa agccatgttg 180gtactgggat aagaaagact tggctcatac accctcacaa cttgaaggac ttgatccagc 240caccgaggcc cggtaccgcc gagagggcgc tcggttcatc tttgatgtgg gcacacgttt 300ggggctacac tatgataccc tggcaactgg aataatttat tttcatcgct tctatatgtt 360tcattccttc aagcaattcc caagatatgt gacaggagcc tgttgcctct ttctggctgg 420gaaagtagaa gaaacaccaa aaaaatgtaa agatatcatc aaaacagctc gtagtttatt 480aaatgatgta caatttggcc agtttggaga tgacccaaag gaggaagtaa tggttctgga 540gagaatctta ctgcagacca tcaagtttga tttacaggta gaacatccat accagttcct 600actaaaatat gcaaagcaac tcaaaggtga taaaaacaaa attcaaaagt tggttcaaat 660ggcatggaca tttgtaaatg acagtctctg caccaccttg tcactgcagt gggaaccaga 720gatcatagca gtagcagtga tgtatctcgc aggacgtttg tgcaaatttg aaatacaaga 780atggacctcc aaacccatgt ataggagatg gtgggagcag tttgttcaag atgtcccggt 840cgacgttttg gaagacatct gccaccaaat cctggatctt tactcacaag gaaaacaaca 900gatgcctcat cacacccccc atcagctgca acagccccca tctcttcagc ctacaccaca 960agtgccgcaa gtacagcagt cacagccgtc tcaaagctcc gaaccatccc agccccagca 1020gaaggacccc ctcatcctcc tccagggttg ggcctgccgc cagccagcta cccacctcct 1080gccgtccccc ctggaggaca gcctcctgtg cccccgccca ttcccccacc cggcatgcct 1140ccagttgggg ggctggggcg ggcagcctgg atgagataac gtgagccttt tttccctctt 1200tgttttttta acaagatttt ctaatcgact tgcagagtag ttgaagtggg taagcagcag 1260ggtaccttgt ataatgcacg acagttgcag tatgggaaga atggaccggg cccctgggat 1320aaaatcagag tggtcctcac acctagagga cggggacaac cagctttcag agtagcctca 1380tcagtgccct tgcagtctga ctgtgtacac ttggttcagc taatgtctga gagtcctgca 1440ctgggttact ttatactagt gaggacgtta accagccata ttggctcaat aaatagcttc 1500ggtaaggagt taatttcctt ctagaaatca gtgcctattt ttcctggaaa ctcaatttta 1560aatagtccaa ttccatctga agccaagctg ttgtcatttt cattcggtga cattctctcc 1620catgacaccc agaaggggca gaagaaccac atttttcatt tatagatgtt tgcatccttt 1680gtattaaaat tattttgaag gggttgcctc attggatggc tttttttttc ctccagggag 1740aaggggagaa atgtacttgg aaattaatgt atgtttacat ctctttgcaa attcctgtac 1800atagagatat attttttaag tgtgaatgta acaacatact gtgaattcca tcttggttac 1860aaatgagact ccttcagtca gttatccaaa taaaagcagt tctgaaacta aaaaaaaaaa 1920aaaaa 1925214134DNAHomo sapiens 21aggcctccct cgccagcggg gtgtggctcc cctccaaaga cggtcggctg acaggctcca 60cagagctcca ctcacgctca gccctggacg gacaggcagt ccaacggaac agaaacatcc 120ctcagcccac aggcacgatc tgttcctcct gggaagatgc agaggctcat gatgctcctc 180gccacatcgg gcgcctgcct gggcctgctg gcagtggcag cagtggcagc agcaggtgct 240aaccctgccc aacgggacac ccacagcctg ctgcccaccc accggcgcca aaagagagat 300tggatttgga accagatgca cattgatgaa gagaaaaaca cctcacttcc ccatcatgta 360ggcaagatca agtcaagcgt gagtcgcaag aatgccaagt acctgctcaa aggagaatat 420gtgggcaagg tcttccgggt cgatgcagag acaggagacg tgttcgccat tgagaggctg 480gaccgggaga atatctcaga gtaccacctc actgctgtca ttgtggacaa ggacactggc 540gaaaacctgg agactccttc cagcttcacc atcaaagttc atgacgtgaa cgacaactgg 600cctgtgttca cgcatcggtt gttcaatgcg tccgtgcctg agtcgtcggc tgtggggacc 660tcagtcatct ctgtgacagc agtggatgca gacgacccca ctgtgggaga ccacgcctct 720gtcatgtacc aaatcctgaa ggggaaagag tattttgcca tcgataattc tggacgtatt 780atcacaataa cgaaaagctt ggaccgagag aagcaggcca ggtatgagat cgtggtggaa 840gcgcgagatg cccagggcct ccggggggac tcgggcacgg ccaccgtgct ggtcactctg 900caagacatca atgacaactt ccccttcttc acccagacca agtacacatt tgtcgtgcct 960gaagacaccc gtgtgggcac ctctgtgggc tctctgtttg ttgaggaccc agatgagccc 1020cagaaccgga tgaccaagta cagcatcttg cggggcgact accaggacgc tttcaccatt 1080gagacaaacc ccgcccacaa cgagggcatc atcaagccca tgaagcctct ggattatgaa 1140tacatccagc aatacagctt catcgtcgag gccacagacc ccaccatcga cctccgatac 1200atgagccctc ccgcgggaaa cagagcccag gtcattatca acatcacaga tgtggacgag 1260ccccccattt tccagcagcc tttctaccac ttccagctga aggaaaacca gaagaagcct 1320ctgattggca cagtgctggc catggaccct gatgcggcta ggcatagcat tggatactcc 1380atccgcagga ccagtgacaa gggccagttc ttccgagtca caaaaaaggg ggacatttac 1440aatgagaaag aactggacag agaagtctac ccctggtata acctgactgt ggaggccaaa 1500gaactggatt ccactggaac ccccacagga aaagaatcca ttgtgcaagt ccacattgaa 1560gttttggatg agaatgacaa tgccccggag tttgccaagc cctaccagcc caaagtgtgt 1620gagaacgctg tccatggcca gctggtcctg cagatctccg caatagacaa ggacataaca 1680ccacgaaacg tgaagttcaa attcatcttg aatactgaga acaactttac cctcacggat 1740aatcacgata acacggccaa catcacagtc aagtatgggc agtttgaccg ggagcatacc 1800aaggtccact tcctacccgt ggtcatctca gacaatggga tgccaagtcg cacgggcacc 1860agcacgctga ccgtggccgt gtgcaagtgc aacgagcagg gcgagttcac cttctgcgag 1920gatatggccg cccaggtggg cgtgagcatc caggcagtgg tagccatctt actctgcatc 1980ctcaccatca cagtgatcac cctgctcatc ttcctgcggc ggcggctccg gaagcaggcc 2040cgcgcgcacg gcaagagcgt gccggagatc cacgagcagc tggtcaccta cgacgaggag 2100ggcggcggcg agatggacac caccagctac gatgtgtcgg tgctcaactc ggtgcgccgc 2160ggcggggcca agcccccgcg gcccgcgctg gacgcccggc cttccctcta tgcgcaggtg 2220cagaagccac cgaggcacgc gcctggggca cacggagggc ccggggagat ggcagccatg 2280atcgaggtga agaaggacga ggcggaccac gacggcgacg gcccccccta cgacacgctg 2340cacatctacg gctacgaggg ctccgagtcc atagccgagt ccctcagctc cctgggcacc 2400gactcatccg actctgacgt ggattacgac ttccttaacg actggggacc caggtttaag 2460atgctggctg agctgtacgg ctcggacccc cgggaggagc tgctgtatta ggcggccgag 2520gtcactctgg gcctggggac ccaaaccccc tgcagcccag gccagtcaga cgccaggcac 2580cacagcctcc aaaaatggca gtgactcccc agcccagcac cccttcctcg tgggtcccag 2640agacctcatc agccttggga tagcaaactc caggttcctg aaatatccag gaatatatgt 2700cagtgatgac tattctcaaa tgctggcaaa tccaggctgg tgttctgtct gggctcagac 2760atccacataa ccctgtcacc cacagaccgc cgtctaactc aaagacttcc tctggctccc 2820caaggctgca aagcaaaaca gactgtgttt aactgctgca gggtcttttt ctagggtccc 2880tgaacgccct ggtaaggctg gtgaggtcct ggtgcctatc tgcctggagg caaaggcctg 2940gacagcttga cttgtggggc aggattctct gcagcccatt cccaagggag actgaccatc 3000atgccctctc tcgggagccc tagccctgct ccaactccat actccactcc aagtgcccca 3060ccactcccca acccctctcc aggcctgtca agagggagga aggggcccca tggcagctcc 3120tgaccttggg tcctgaagtg acctcactgg cctgccatgc cagtaactgt gctgtactga 3180gcactgaacc acattcaggg aaatggctta ttaaactttg aagcaactgt gaattcattc 3240tggaggggca gtggagatca ggagtgacag atcacagggt gagggccacc tccacaccca 3300ccccctctgg agaaggcctg gaagagctga gaccttgctt tgagactcct cagcacccct 3360ccagttttgc ctgagaaggg gcagatgttc ccggagcaga agacgtctcc ccttctctgc 3420ctcacctggt cgccaatcca tgctctcttt cttttctctg tctactcctt atcccttggt 3480ttagaggaac ccaagatgtg gcctttagca aaactggaca atgtccaaac ccactcatga 3540ctgcatgacg gagccgagcc atgtgtcttt acacctcgct gttgtcacat ctcagggaac 3600tgaccctcag gcacaccttg cagaaggcaa ggccctgccc tgcccaacct ctgtggtcac 3660ccatgcatct tccactggaa cgtttcactg caaacacacc ttggagaagt ggcatcagtc 3720aacagagagg ggcagggaag gagacaccaa gctcaccctt cgtcatggac cgaggttccc 3780actctgggca aagcccctca cactgcaagg gattgtagat aacactgact tgtttgtttt 3840aaccaataac tagcttctta taatgatttt tttactaatg atacttacaa gtttctagct 3900ctcacagaca tatagaataa gggtttttgc ataataagca ggttgttatt taggttaaca 3960atattaattc aggtttttta gttggaaaaa caattcctgt aaccttctat tttctataat 4020tgtagtaatt gctctacaga taatgtctat atattggcca aactggtgca tgacaagtac 4080tgtatttttt tatacctaaa taaagaaaaa tctttagcct gggcaacaaa aaaa 4134222325DNAHomo sapiens 22gcgggaagca ggggcggggc ctctggtggc ggtcgggaac tcggtgggag gcggcaacat 60tgtttcaagt tggccaaatt gacaagagcg agaggtatac tgcgttccat cccgacccgg 120ggccacggta ctgggccctg tttccccctc ctcggccccc gagagccagg gtccgccttc 180tgcagggttc ccaggccccc gctccagggc cgggctgacc cgactcgctg gcgcttcatg 240gagaacttcc aaaaggtgga aaagatcgga gagggcacgt acggagttgt gtacaaagcc 300agaaacaagt tgacgggaga ggtggtggcg cttaagaaaa tccgcctgga cactgagact 360gagggtgtgc ccagtactgc catccgagag atctctctgc ttaaggagct taaccatcct 420aatattgtca agctgctgga tgtcattcac acagaaaata aactctacct ggtttttgaa 480tttctgcacc aagatctcaa gaaattcatg gatgcctctg ctctcactgg cattcctctt 540cccctcatca agagctatct gttccagctg ctccagggcc tagctttctg ccattctcat 600cgggtcctcc accgagacct taaacctcag aatctgctta ttaacacaga gggggccatc 660aagctagcag actttggact agccagagct tttggagtcc ctgttcgtac ttacacccat 720gaggtggtga ccctgtggta ccgagctcct gaaatcctcc tgggctgcaa atattattcc 780acagctgtgg acatctggag cctgggctgc atctttgctg agatggtgac tcgccgggcc 840ctattccctg gagattctga gattgaccag ctcttccgga tctttcggac tctggggacc 900ccagatgagg tggtgtggcc aggagttact tctatgcctg attacaagcc aagtttcccc 960aagtgggccc ggcaagattt tagtaaagtt gtacctcccc tggatgaaga tggacggagc 1020ttgttatcgc aaatgctgca ctacgaccct aacaagcgga tttcggccaa ggcagccctg 1080gctcaccctt tcttccagga tgtgaccaag ccagtacccc atcttcgact ctgatagcct 1140tcttgaagcc cccagcccta atctcaccct ctcctccagt gtgggcttga ccaggcttgg 1200ccttgggcta tttggactca ggtgggccct ctgaacttgc cttaaacact caccttctag 1260tcttggccag ccaactctgg gaatacaggg gtgaaagggg ggaaccagtg aaaatgaaag 1320gaagtttcag tattagatgc acttaagtta gcctccacca ccctttcccc cttctcttag 1380ttattgctga agagggttgg tataaaaata attttaaaaa agccttccta cacgttagat 1440ttgccgtacc aatctctgaa tgccccataa ttattatttc cagtgtttgg gatgaccagg 1500atcccaagcc tcctgctgcc acaatgttta taaaggccaa atgatagcgg gggctaagtt 1560ggtgcttttg agaaccaagt aaaacaaaac cactgggagg agtctatttt aaagaattcg 1620gttgaaaaaa tagatccaat cagtttatac cctagttagt gttttgcctc acctaatagg 1680ctgggagact gaagactcag cccgggtggg gctgcagaaa aatgattggc cccagtcccc 1740ttgtttgtcc cttctacagg catgaggaat ctgggaggcc ctgagacagg gattgtgctt 1800cattccaatc tattgcttca ccatggcctt atgaggcagg tgagagatgt ttgaattttt 1860ctcttccttt tagtattctt agttgttcag ttgccaagga tccctgatcc cattttcctc 1920tgacgtccac ctcctacccc ataggagtta gaagttaggg tttaggcatc attttgagaa 1980tgctgacact ttttcagggc tgtgattgag tgagggcatg ggtaaaaata tttctttaaa 2040agaaggatga acaattatat ttatatttca ggttatatcc aatagtagag ttggcttttt 2100tttttttttt ttggtcatag tgggtggatt tgttgccatg tgcaccttgg ggttttgtaa 2160tgacagtgct aaaaaaaaaa agcatttttt ttttatgatt tgtctctgtc acccttgtcc 2220ttgagtgctc ttgctattaa cgttatttgt aatttagttt gtagctcatt aaaaaaatgt 2280gcctagtttt ataaaaaaaa aaaaaaaaaa caaaaaaaaa

aaaaa 2325233837DNAHomo sapiens 23agaagaagga gcaggagcag atgctaaagg aagagaggaa acgcgagttg gaggagaagg 60tcaaggcagt ggaagatcga gcgaagagga gaaagctcag ggaagaaagg gcatggctgc 120tggctcaagg aaaggagctc cctccagaac tttcccatct ggaccccaat tcccccatga 180gagaggaaaa aaagactaaa gacctctttg agttggatga tgatttcact gctatgtata 240aagttctaga cgtggtaaag gctcacaagg attcctggcc cttcttggaa cctgtggatg 300aatcttatgc ccctaactat tatcagatta ttaaggcccc catggatatt tccagcatgg 360agaagaaact gaatggaggt ttatactgta ccaaggagga atttgtaaat gacatgaaga 420ccatgttcag gaattgtcga aagtataatg gggaaagtag tgagtatacc aagatgtctg 480ataatttaga gaggtgtttc catcgggcaa tgatgaaaca ttttcctgga gaagatggag 540acacagatga agaattttgg attcgagagg atgaaaagcg ggagaaaaga cggagtcggg 600ctgggcgaag tggtgggagc catgtttgga cccgctccag ggacccagaa gggtccagca 660ggaaacagca gcccatggag aatggaggaa agtcgttgcc ccccacacgc cgagcgccct 720cttctgggga cgatcagagc agcagctcca cacagccccc gcgggaggtg ggcacttcca 780atggccgagg tttttctcat cccctgcatt gtggtgggac acccagccag gcaccctttt 840taaaccagat gaggccagca gtaccaggaa catttggccc tctgcgagga tcagatcctg 900ccaccttgta tggctcctct ggagtcctgg agccacaccc cggggagcct gtgcagcagc 960gtcagccttt caccatgcag cctccagttg gaattaacag cctccgagga cccaggctag 1020gcacaccaga ggagaagcaa atgtgcgggg ggctgacaca cctttctaac atgggcccac 1080accctggatc cttgcagctt gggcagataa gtggcccaag tcaggatgga agcatgtatg 1140ctccagctca gttccagcca ggattcattc ctccccggca tgggggggct ccagcccggc 1200caccagactt tcctgaaagc tcagaaattc ctcccagcca tatgtatcga tcgtacaagt 1260acctgaatcg agtacactct gccgtctgga atgggaacca tggtgctacg aaccaaggac 1320ccttgggccc agatgagaag ccccacctgg ggccaggacc ctctcaccag cctcgcactc 1380tcggtcacgt gatggattcc cgagtcatga gaccacctgt cccccccaac cagtggactg 1440aacaatcagg cttcctacct catggagttc cttcctcagg gtacatgcga ccgccctgca 1500agtctgccgg acatcggtta cagccacctc cagtgccagc acccagttct ttgtttggag 1560cacctgccca ggctcttcgg ggggtgcagg gaggggactc catgatggac agcccagaga 1620tgattgcgat gcagcagctc tcctcccgcg tctgcccccc aggtgtgcct taccaccccc 1680accagcctgc acacccccgt ttacctggcc cttttccgca ggtagctcac ccaatgtcag 1740tcactgtgtc agcccccaag cctgccctgg gcaaccctgg gagggcaccg gagaacagtg 1800aagcacaaga gcctgagaat gaccaagcag agccgttgcc tggccttgaa gagaaaccac 1860caggtgttgg tacttcagag ggggtctacc tcacacaact acctcacccc acacctcccc 1920tgcagactga ctgcaccagg cagagctcac cacaagaaag ggaaacagtg ggcccggagc 1980tcaaaagcag ctcctccgaa tctgcggaca actgtaaagc aatgaagggc aagaatccct 2040ggccctcgga tagcagctac cccggcccag ccgcccaagg gtgcgtgaga gacctctcca 2100cggtggcaga caggggcgct ctatccgaga acggagtcat tggggaagca tctccttgtg 2160gatcggaggg gaagggcctt ggtagcagtg gttccgaaaa gctgctctgc cccagaggca 2220gaacgttgca ggaaaccatg ccatgcacgg gacagaacgc agcgacaccg cccagcacag 2280accccggttt gacgggaggc actgtgagcc agtttccccc gctgtatatg cctggcctag 2340agtacccgaa ttcagctgcc cattaccaca tcagtccagg cctgcagggt gtgggccctg 2400tgatgggagg gaagtcccca gcatcccatc cccagcattt tcccccaagg ggctttcagt 2460ctaaccaccc acattctgga ggctttcccc ggtatcgccc cccacaagga atgaggtatt 2520cctaccaccc accgccacag ccttcctacc accactatca gcgaactcct tactatgcct 2580gtccacagag cttttctgac tggcagagac ctctccatcc ccagggaagc ccaagcggac 2640ccccagccag tcagcctccc ccaccaaggt ccctcttctc agataagaat gccatggcca 2700gtctgcaagg ctgtgagaca ctgaatgctg ccttaacttc tccaacccgt atggatgcag 2760tggctgctaa agtcccaaat gacgggcaga atcctggtcc agaggaagag aagctggatg 2820aatctatgga gaggccagag agtcccaaag aatttttaga cctggacaac cataacgcag 2880ctaccaagcg gcagagctcg ttgtcagcca gcgagtatct ctatggaact cctccgcctc 2940tgagttcagg aatgggattt ggttcatctg catttccacc ccacagtgtg atgctgcaga 3000cggggcctcc ctatacccct cagcggccgg ccagtcactt tcagcccagg gcttactctt 3060cccctgtggc tgccctccca cctcaccacc caggggccac ccagcccaac ggcctctctc 3120aggagggtcc catctatcgc tgccaggaag aaggcctggg tcactttcaa gctgtgatga 3180tggaacaaat tggcactaga agtggaataa gaggaccttt ccaggaaatg tacagaccat 3240caggaatgca gatgcacccg gtccagtcgc aggcctcgtt cccaaagacc cccacagcag 3300caacatcaca ggaggaggtg ccgcctcata agcctccaac acttcccctg gatcagagct 3360agtccaagga ggaaatgagc cccaagcaat ggaaagctgc acacgaagac tggaatgtgg 3420agaactgggg agtgccctgt cagctctatt cccatcacct gctccacccc ttcacggcga 3480cccactcgtg ccatacttga gctggagcca gtcacgggcc ctaaaaggac actccttaga 3540tgactgacac acagattgca aaggtcctcg gccagggatc tcttgcacag ctgatgtaga 3600cagtcaggca aaactaatga acgtggagtt aatgatgact tttccaaatc ctgagacact 3660tttcagggaa aatcacttta aacttggggg agggggtata ctcaagaatg gagtggtgct 3720tttaaacttt gatgagcagc taaactcagg tatatatttg gggaagggac tactcttagt 3780attaatggtt ttggagctgg gtccagttta cagaattttc atgttgcctt ttaaaat 3837245773DNAHomo sapiens 24aaagatcgct gtgcagtcag ccttaaacac tgactgcacc cctcccagat ttcttttaca 60ttaactaaaa agtcttatca cacaatctca taaaatttat gtaatttcat ttaattttag 120ccacaaatca tcaaaatgac gaggattttg acagctttca aagtggtgag gacactgaag 180actggttttg gctttaccaa tgtgactgca caccaaaaat ggaaattttc aagacctggc 240atcaggctcc tttctgtcaa ggcacagaca gcacacattg tcctggaaga tggaactaag 300atgaaaggtt actcctttgg ccatccatcc tctgttgctg gtgaagtggt ttttaatact 360ggcctgggag ggtacccaga agctattact gaccctgcct acaaaggaca gattctcaca 420atggccaacc ctattattgg gaatggtgga gctcctgata ctactgctct ggatgaactg 480ggacttagca aatatttgga gtctaatgga atcaaggttt caggtttgct ggtgctggat 540tatagtaaag actacaacca ctggctggct accaagagtt tagggcaatg gctacaggaa 600gaaaaggttc ctgcaattta tggagtggac acaagaatgc tgactaaaat aattcgggat 660aagggtacca tgcttgggaa gattgaattt gaaggtcagc ctgtggattt tgtggatcca 720aataaacaga atttgattgc tgaggtttca accaaggatg tcaaagtgta cggcaaagga 780aaccccacaa aagtggtagc tgtagactgt gggattaaaa acaatgtaat ccgcctgcta 840gtaaagcgag gagctgaagt gcacttagtt ccctggaacc atgatttcac caagatggag 900tatgatggga ttttgatcgc gggaggaccg gggaacccag ctcttgcaga accactaatt 960cagaatgtca gaaagatttt ggagagtgat cgcaaggagc cattgtttgg aatcagtaca 1020ggaaacttaa taacaggatt ggctgctggt gccaaaacct acaagatgtc catggccaac 1080agagggcaga atcagcctgt tttgaatatc acaaacaaac aggctttcat tactgctcag 1140aatcatggct atgccttgga caacaccctc cctgctggct ggaaaccact ttttgtgaat 1200gtcaacgatc aaacaaatga ggggattatg catgagagca aacccttctt cgctgtgcag 1260ttccacccag aggtcacccc ggggccaata gacactgagt acctgtttga ttcctttttc 1320tcactgataa agaaaggaaa agctaccacc attacatcag tcttaccgaa gccagcacta 1380gttgcatctc gggttgaggt ttccaaagtc cttattctag gatcaggagg tctgtccatt 1440ggtcaggctg gagaatttga ttactcagga tctcaagctg taaaagccat gaaggaagaa 1500aatgtcaaaa ctgttctgat gaacccaaac attgcatcag tccagaccaa tgaggtgggc 1560ttaaagcaag cggatactgt ctactttctt cccatcaccc ctcagtttgt cacagaggtc 1620atcaaggcag aacagccaga tgggttaatt ctgggcatgg gtggccagac agctctgaac 1680tgtggagtgg aactattcaa gagaggtgtg ctcaaggaat atggtgtgaa agtcctggga 1740acttcagttg agtccattat ggctacggaa gacaggcagc tgttttcaga taaactaaat 1800gagatcaatg aaaagattgc tccaagtttt gcagtggaat cgattgagga tgcactgaag 1860gcagcagaca ccattggcta cccagtgatg atccgttccg cctatgcact gggtgggtta 1920ggctcaggca tctgtcccaa cagagagact ttgatggacc tcagcacaaa ggcctttgct 1980atgaccaacc aaattctggt ggagaagtca gtgacaggtt ggaaagaaat agaatatgaa 2040gtggttcgag atgctgatga caattgtgtc actgtctgta acatggaaaa tgttgatgcc 2100atgggtgttc acacaggtga ctcagttgtt gtggctcctg cccagacact ctccaatgcc 2160gagtttcaga tgttgagacg tacttcaatc aatgttgttc gccacttggg cattgtgggt 2220gaatgcaaca ttcagtttgc ccttcatcct acctcaatgg aatactgcat cattgaagtg 2280aatgccagac tgtcccgaag ctctgctctg gcctcaaaag ccactggcta cccattggca 2340ttcattgctg caaagattgc cctaggaatc ccacttccag aaattaagaa cgtcgtatcc 2400gggaagacat cagcctgttt tgaacctagc ctggattaca tggtcaccaa gattccccgc 2460tgggatcttg accgttttca tggaacatct agccgaattg gtagctctat gaaaagtgta 2520ggagaggtca tggctattgg tcgtaccttt gaggagagtt tccagaaagc tttacggatg 2580tgccacccat ctatagaagg tttcactccc cgtctcccaa tgaacaaaga atggccatct 2640aatttagatc ttagaaaaga gttgtctgaa ccaagcagca cgcgtatcta tgccattgcc 2700aaggccattg atgacaacat gtcccttgat gagattgaga agctcacata cattgacaag 2760tggtttttgt ataagatgcg tgatatttta aacatggaaa agacactgaa aggcctcaac 2820agtgagtcca tgacagaaga aaccctgaaa agggcaaagg agattgggtt ctcagataag 2880cagatttcaa aatgccttgg gctcactgag gcccagacaa gggagctgag gttaaagaaa 2940aacatccacc cttgggttaa acagattgat acactggctg cagaataccc atcagtaaca 3000aactatctct atgttaccta caatggtcag gagcatgatg tcaattttga tgaccatgga 3060atgatggtgc taggctgtgg tccatatcac attggcagca gtgtggaatt tgattggtgt 3120gctgtctcta gtatccgcac actgcgtcaa cttggcaaga agacggtggt ggtgaattgc 3180aatcctgaga ctgtgagcac agactttgat gagtgtgaca aactgtactt tgaagagttg 3240tccttggaga gaatcctaga catctaccat caggaggcat gtggtggctg catcatatca 3300gttggaggcc agattccaaa caacctggca gttcctctat acaagaatgg tgtcaagatc 3360atgggcacaa gccccctgca gatcgacagg gctgaggatc gctccatctt ctcagctgtc 3420ttggatgagc tgaaggtggc tcaggcacct tggaaagctg ttaatacttt gaatgaagca 3480ctggaatttg caaagtctgt ggactacccc tgcttgttga ggccttccta tgttttgagt 3540gggtctgcta tgaatgtggt attctctgag gatgagatga aaaaattcct agaagaggcg 3600actagagttt ctcaggagca cccagtggtg ctgacaaaat ttgttgaagg ggcccgagaa 3660gtagaaatgg acgctgttgg caaagatgga agggttatct ctcatgccat ctctgaacat 3720gttgaagatg caggtgtcca ctcgggagat gccactctga tgctgcccac acaaaccatc 3780agccaagggg ccattgaaaa ggtgaaggat gctacccgga agattgcaaa ggcttttgcc 3840atctctggtc cattcaacgt ccaatttctt gtcaaaggaa atgatgtctt ggtgattgag 3900tgtaacttga gagcttctcg atccttcccc tttgtttcca agactcttgg ggttgacttc 3960attgatgtgg ccaccaaggt gatgattgga gagaatgttg atgagaaaca tcttccaaca 4020ttggaccatc ccataattcc tgctgactat gttgcaatta aggctcccat gttttcctgg 4080ccccggttga gggatgctga ccccattctg agatgtgaga tggcttccac tggagaggtg 4140gcttgctttg gtgaaggtat tcatacagcc ttcctaaagg caatgctttc cacaggattt 4200aagatacccc agaaaggcat cctgataggc atccagcaat cattccggcc aagattcctt 4260ggtgtggctg aacaattaca caatgaaggt ttcaagctgt ttgccacgga agccacatca 4320gactggctca acgccaacaa tgtccctgcc accccagtgg catggccgtc tcaagaagga 4380cagaatccca gcctctcttc catcagaaaa ttgattagag atggcagcat tgacctagtg 4440attaaccttc ccaacaacaa cactaaattt gtccatgata attatgtgat tcggaggaca 4500gctgttgata gtggaatccc tctcctcact aattttcagg tgaccaaact ttttgctgaa 4560gctgtgcaga aatctcgcaa ggtggactcc aagagtcttt tccactacag gcagtacagt 4620gctggaaaag cagcatagag atgcagacac cccagcccca ttattaaatc aacctgagcc 4680acatgttatc taaaggaact gattcacaac tttctcagag atgaatattg ataactaaac 4740ttcatttcag tttactttgt tatgccttaa tattctgtgt cttttgcaat taaattgtca 4800gtcacttctt caaaacctta cagtccttcc taagttactc ttcatgagat ttcatccatt 4860tactaatact gtatttttgg tggactaggc ttgcctatgt gcttatgtgt agctttttac 4920tttttatggt gctgattaat ggtgatcaag gtaggaaaag ttgctgttct attttctgaa 4980ctctttctat actttaagat actctatttt taaaacacta tctgcaaact caggacactt 5040taacagggca gaatactcta aaaacttgat aaaattaaat atagatttaa tttatgaacc 5100ttccatcatg atgtttgtgt attgcttctt tttggatcct cattctcacc catttggcta 5160atccaggaat attgttatcc cttcccatta tattgaagtt gagaaatgtg acagaggcat 5220ttagagtatg gacttttctt ttctttttct ttttcttttt ttctttttga gatggagtca 5280cactctccag gctggagtgc agtggcacaa tctcggctca ctgcaatttc cgtctcccaa 5340gttcaagcga ttctcctgct ttagactatg gatttcttta aggaatactg gtttgcagtt 5400ttgttttctg gactatatca gcagatggta gacagtgttt atgtagatgt gttgttgttt 5460ttatcattgg attttaactt ggcccgagtg aaataatcag atttttgtca ttcacactct 5520cccccagttt tggaataact tggaagtaag gttcattccc ttaagacgat ggattctgtt 5580gaactatggg gtcccacact gcactattaa ttccacccac tgtaagggca aggacaccat 5640tccttctaca tataagaaaa aagtctctcc ccaagggcag cctttgttac ttttaaatat 5700tttctgttat tacaagtgct ctaattgtga acttttaaat aaaatactat taagaggtaa 5760aaaaaaaaaa aaa 5773251201DNAHomo sapiens 25gccattaaca aagatggtgc ttatggggca ggttccctaa cagtcaggat tccggttgca 60gtttttctcc cccgccccaa agatacgtgg ttgcagacgg agaaatggag gccagagaca 120aacaagtact ccgctcactt cgcctggagc tgggtgcaga ggtattggtg gagggactgg 180ttcttcagta cctctaccag gaaggaatct tgacggaaaa ccatattcaa gaaatcaatg 240ctcaaaccac aggcctccgg aaaacaatgc tcctgctgga tatcctacct tccaggggcc 300ctaaagcatt tgatacattc ctagattccc tacaggagtt tccctgggtc agggagaagc 360tgaagaaggc aagggaagag gccatgaccg acctgcctgc aggtgacaga ttgactggga 420tcccctcgca catcctcaac agctccccat cagaccggca gattaaccag ctggcccaga 480ggctgggccc tgagtgggag cccatggtgc tgtctctggg actgtcccag acggatatct 540accgctgtaa ggccaaccac ccccacaacg tgcagtcgca ggtggtggag gccttcatcc 600gttggcggca gcgcttcggg aagcaggcca ccttccagag cctgcacaac gggctgcggg 660ctgtggaggt ggacccctcg ctgctcctgc acatgttgga gtgatggtgc ctccagcaac 720cgctggggag tgtgtccctg agtcatgtgg gctgaatcct gactttcact cagagcaggt 780ggttttttgt gtaggtttgt tttttatttt tgatgatctt cagatggaag gagaaaacag 840ggtttccact agacattact tgaaaggcca gattactcag cagatctccc atgttggctc 900aacaattctt tgtttttaat tgcttgaaga ttgcattgtt gtaattgttc agtttttaaa 960tgtgtaatgg cattttaata gactagtaaa tcacagtggt tcaaaatata tatccatata 1020tatatatatc catatatata tctcatgtca tcacattaca ggcaggtgtc tcatatgtaa 1080aacatttacc tgaatgttgt ctgaggactg aactgtggac tttactattc ataatgataa 1140aataataaaa tgcgaattac tatatataat gtgcctcact catgagaaaa aaaaaaaaaa 1200a 1201268310DNAHomo sapiens 26aagtgccgtt tcggtttaat ctagtgtgtg actgggtctg tgtgagggag agagtgtgtg 60tggtgtggag gtgaaacgga ggcaagaaag ggggctacct caggagcgag ggacaaaggg 120ggcgtgaggc acctaggccg cggcaccccg gcgacaggaa gccgtcctga accgggctac 180cgggtagggg aagggcccgc gtagtcctcg cagggcccca gagctggagt cggctccaca 240gccccgggcc gtcggcttct cacttcctgg acctccccgg cgcccgggcc tgaggactgg 300ctcggcggag ggagaagagg aaacagactt gagcagctcc ccgttgtctc gcaactccac 360tgccgaggaa ctctcatttc ttccctcgct ccttcacccc ccacctcatg tagaagggtg 420ctgaggcgtc gggagggagg aggagcctgg gctaccgtcc ctgccctccc cacccccttc 480ccggggcgct ttggtgggcg tggagttggg gttggggggg tgggtggggg ttgctttttg 540gagtgctggg gaactttttt cccttcttca ggtcagggga aagggaatgc ccaattcaga 600gagacatggg ggcaagaagg acgggagtgg aggagcttct ggaactttgc agccgtcatc 660gggaggcggc agctctaaca gcagagagcg tcaccgcttg gtatcgaagc acaagcggca 720taagtccaaa cactccaaag acatggggtt ggtgaccccc gaagcagcat ccctgggcac 780agttatcaaa cctttggtgg agtatgatga tatcagctct gattccgaca ccttctccga 840tgacatggcc ttcaaactag accgaaggga gaacgacgaa cgtcgtggat cagatcggag 900cgaccgcctg cacaaacatc gtcaccacca gcacaggcgt tcccgggact tactaaaagc 960taaacagacc gaaaaagaaa aaagccaaga agtctccagc aagtcgggat cgatgaagga 1020ccggatatcg ggaagttcaa agcgttcgaa tgaggagact gatgactatg ggaaggcgca 1080ggtagccaaa agcagcagca aggaatccag gtcatccaag ctccacaagg agaagaccag 1140gaaagaacgg gagctgaagt ctgggcacaa agaccggagt aaaagtcatc gaaaaaggga 1200aacacccaaa agttacaaaa cagtggacag cccaaaacgg agatccagga gcccccacag 1260gaagtggtct gacagctcca aacaagatga tagcccctcg ggagcttctt atggccaaga 1320ttatgacctt agtccctcac gatctcatac ctcgagcaat tatgactcct acaagaaaag 1380tcctggaagt acctcgagaa ggcagtcggt cagtccccct tacaaggagc cttcggccta 1440ccagtccagc acccggtcac cgagccccta cagtaggcga cagagatctg tcagtcccta 1500tagcaggaga cggtcgtcca gctacgaaag aagtggctct tacagcgggc gatcgcccag 1560tccctatggt cgaaggcggt ccagcagccc tttcctgagc aagcggtctc tgagtcggag 1620tccactcccc agtaggaaat ccatgaagtc cagaagtaga agtcctgcat attcaagaca 1680ttcatcttct catagtaaaa agaagagatc cagttcacgc agtcgtcatt ccagtatctc 1740acctgtcagg cttccactta attccagtct gggagctgaa ctcagtagga aaaagaagga 1800aagagcagct gctgctgctg cagcaaagat ggatggaaag gagtccaagg gttcacctgt 1860atttttgcct agaaaagaga acagttcagt agaggctaag gattcaggtt tggagtctaa 1920aaagttaccc agaagtgtaa aattggaaaa atctgcccca gatactgaac tggtgaatgt 1980aacacatcta aacacagagg taaaaaattc ttcagataca gggaaagtaa agttggatga 2040gaactccgag aagcatcttg ttaaagattt gaaagcacag ggaacaagag actctaaacc 2100catagcactg aaagaggaga ttgttactcc aaaggagaca gaaacatcag aaaaggagac 2160ccctccacct cttcccacaa ttgcttctcc cccaccccct ctaccaacta ctacccctcc 2220acctcagaca ccccctttgc cacctttgcc tccaatacca gctcttccac agcaaccacc 2280tctgcctcct tctcagccag catttagtca ggttcctgct tccagtactt caactttgcc 2340cccttctact cactcaaaga catctgctgt gtcctctcag gcaaattctc agccccctgt 2400acaggtttct gtgaagactc aagtatctgt aacagctgct attccacacc tgaaaacttc 2460aacgttgcct cctttgcccc tcccaccctt attacctgga gatgatgaca tggatagtcc 2520aaaagaaact cttccttcaa aacctgtgaa gaaagagaag gaacagagga cacgtcactt 2580actcacagac cttcctctcc ctccagagct ccctggtgga gatctgtctc ccccagactc 2640tccagaacca aaggcaatca caccacctca gcaaccatat aaaaagagac caaaaatttg 2700ttgtcctcgt tatggagaaa gaagacaaac agaaagcgac tgggggaaac gctgtgtgga 2760caagtttgac attattggga ttattggaga aggaacctat ggccaagtat ataaagccaa 2820ggacaaagac acaggagaac tagtggctct gaagaaggtg agactagaca atgagaaaga 2880gggcttccca atcacagcca ttcgtgaaat caaaatcctt cgtcagttaa tccaccgaag 2940tgttgttaac atgaaggaaa ttgtcacaga taaacaagat gcactggatt tcaagaagga 3000caaaggtgcc ttttaccttg tatttgagta tatggaccat gacttaatgg gactgctaga 3060atctggtttg gtgcactttt ctgaggacca tatcaagtcg ttcatgaaac agctaatgga 3120aggattggaa tactgtcaca aaaagaattt cctgcatcgg gatattaagt gttctaacat 3180tttgctgaat aacagtgggc aaatcaaact agcagatttt ggacttgctc ggctctataa 3240ctctgaagag agtcgccctt acacaaacaa agtcattact ttgtggtacc gacctccaga 3300actactgcta ggagaggaac gttacacacc agccatagat gtttggagct gtggatgtat 3360tcttggggaa ctattcacaa agaagcctat ttttcaagcc aatctggaac tggctcagct 3420agaactgatc agccgacttt gtggtagccc ttgtccagct gtgtggcctg atgttatcaa 3480actgccctac ttcaacacca tgaaaccgaa gaagcaatat cgaaggcgtc tacgagaaga 3540attctctttc attccttctg cagcacttga tttattggac cacatgctga cactagatcc 3600tagtaagcgg tgcacagctg aacagaccct acagagcgac ttccttaaag atgtcgaact 3660cagcaaaatg gctcctccag acctccccca ctggcaggat tgccatgagt tgtggagtaa 3720gaaacggcga cgtcagcgac aaagtggtgt tgtagtcgaa gagccacctc catccaaaac 3780ttctcgaaaa gaaactacct cagggacaag tactgagcct gtgaagaaca gcagcccagc 3840accacctcag cctgctcctg gcaaggtgga gtctggggct ggggatgcaa taggccttgc 3900tgacatcaca caacagctga atcaaagtga attggcagtg ttattaaacc tgctgcagag 3960ccaaaccgac ctgagcatcc ctcaaatggc acagctgctt aacatccact ccaacccaga 4020gatgcagcag cagctggaag

ccctgaacca atccatcagt gccctgacgg aagctacttc 4080ccagcagcag gactcagaga ccatggcccc agaggagtct ttgaaggaag caccctctgc 4140cccagtgatc ctgccttcag cagaacagac gacccttgaa gcttcaagca caccagctga 4200catgcagaat atattggcag ttctcttgag tcagctgatg aaaacccaag agccagcagg 4260cagtctggag gaaaacaaca gtgacaagaa cagtgggcca caggggcccc gaagaactcc 4320cacaatgcca caggaggagg cagcagcatg tcctcctcac attcttccac cagagaagag 4380gccccctgag ccccccggac ctccaccgcc gccacctcca ccccctctgg ttgaaggcga 4440tctttccagc gccccccagg agttgaaccc agccgtgaca gccgccttgc tgcaactttt 4500atcccagcct gaagcagagc ctcctggcca cctgccacat gagcaccagg ccttgagacc 4560aatggagtac tccacccgac cccgtccaaa caggacttat ggaaacactg atgggcctga 4620aacagggttc agtgccattg acactgatga acgaaactct ggtccagcct tgacagaatc 4680cttggtccag accctggtga agaacaggac cttctcaggc tctctgagcc accttgggga 4740gtccagcagt taccagggca cagggtcagt gcagtttcca ggggaccagg acctccgttt 4800tgccagggtc cccttagcgt tacacccggt ggtcgggcaa ccattcctga aggctgaggg 4860aagcagcaat tctgtggtac atgcagagac caaattgcaa aactatgggg agctggggcc 4920aggaaccact ggggccagca gctcaggagc aggccttcac tgggggggcc caactcagtc 4980ttctgcttat ggaaaactct atcgggggcc tacaagagtc ccaccaagag ggggaagagg 5040gagaggagtt ccttactaac ccagagactt cagtgtcctg aaagattcct ttcctatcca 5100tccttccatc cagttctctg aatctttaat gaaatcattt gccagagcga ggtaatcatc 5160tgcatttggc tactgcaaag ctgtccgttg tattccttgc tcacttgcta ctagcaggcg 5220acttacgaaa taatgatgtt ggcaccagtt ccccctggat gggctatagc cagaacattt 5280acttcaactc taccttagta gatacaagta gagaatatgg agaggatcat tacattgaaa 5340agtaaatgtt ttattagttc attgcctgca cttactgatc ggaagagaga aagaacagtt 5400tcagtattga gatggctcag gagaggctct ttgattttta aagttttggg gtgggggatt 5460gtgtgtggtt tctttctttt gaattttaat ttaggtgttt tgggtttttt tcctttaaag 5520agaatagtgt tcacaaaatt tgagctgctc tttggctttt gctataaggg aaacagagtg 5580gcctggctga tttgaataaa tgtttctttc ctctccacca tctcacattt tgcttttaag 5640tgaacacttt ttccccattg agcatcttga acatactttt tttccaaata aattactcat 5700ccttaaagtt tactccactt tgacaaaaga tacgcccttc tccctgcaca taaagcaggt 5760tgtagaacgt ggcattcttg ggcaagtagg tagactttac ccagtctctt tccttttttg 5820ctgatgtgtg ctctctctct ctctttctct ctctctctct ctctctctct ctctctctct 5880ctctctgtct cgcttgctcg ctctcgctgt ttctctctct ttgaggcatt tgtttggaaa 5940aaatcgttga gatgcccaag aacctgggat aattctttac tttttttgaa ataaaggaaa 6000ggaaattcag actcttacat tgttctctgt aactcttcaa ttctaaaatg ttttgttttt 6060taaaccatgt tctgatgggg aagttgattt gtaagtgtgg acagcttgga cattgctgct 6120gagctgtggt tagagatgat gcctccattc ctagagggct aataacagca tttagcatat 6180tgtttacaca tatattttta tgtcaaaaaa aaaacaaaaa cctttcaaac agagcattgt 6240gatattgtca aagagaaaaa caaatcctga agatacatgg aaatgtaacc tagtttaggg 6300tgggtatttt tctgaagata catcaatacc tgaccttttt taaaaaaata attttaaaac 6360agcatactgt gaggaagaac agtattgaca tacccacatc ccagcatgtg taccctgcca 6420gttcttttag ggatttttcc tccaaagaga tttggatttg gttttggtaa aaggggttaa 6480attgtgcttc caggcaagaa ctttgcctta tcataaacag gaaatgaaaa agggaagggc 6540tgtcaggatg ggataatttg ggaggcttct cattctggct tctatttcta tgtgagtacc 6600agcatataga gtgttttaaa aacagataca tgtcatataa tttatctgca cagacttaga 6660ccttcaggaa acataggtta agcccccttt tacaaagaaa aagtaaacat acttcagcat 6720cttggagggt agttttcaaa actcaagttt catgtttcaa tgccaagttc ttattttaaa 6780aaataaaatc tacttataag agaaaggtgc attacttaaa aaaaaaaaac tttaaagaaa 6840tgaaagaaga accctcttca gatacttact tgaagactgt tttcccctgt taatgagata 6900tagctagata tcggtgtgtg tatttcttta ttattctctg gtttttgatc tggccttgcc 6960tccagggcca aacactgatt tagaaagaga gccttctagc tattttggca ttgatggctt 7020tttataccag tgtgtccagt tagatttact aggcttactg acatgctatt ggtaaatcgc 7080attaaagttc atctgaacct tctgtctgtt gacttcttag tcctcagaca tgggcctttg 7140tgttttagaa tatttgaatt tgagttattg ggccccactc cctgtttttt attaaagaac 7200gtgagcctgg gatactttca gaagtatctg ttcaatgaaa aaaagttggt ttcccatcaa 7260atatgaataa aattctctat atatttcatt gtattttggt tatcagcagt catcaataat 7320gtttttccct cccctctccc acctcttatt tttaattatg ccaaatatcc taaataatat 7380acttaagcct ccattccctc atccctacta gggaaggggg tgagtgtatg tgtgagtgta 7440tgtgtatgta tgatcccatc tcacccccac ccccattttg ggagtctttt aaaatgaaaa 7500caaagtttgg tagttttgac tatttctaaa agcagaggag aaaaaaaaac ttatttaaat 7560atcctggaat ctgtatggag gaagaaaagg tatttgttaa tttttcagtt acgttatcta 7620taaacatgat ggaagtaaag gtttggcaga atttcacctt gactatttga aaattacaga 7680cccaattaat tccattcaaa agtggttttc gttttgtttt aattattgta caatgagaga 7740tattgtctat taaatacatt attttgaaca gatgagaaat ctgattctgt tcatgagtgg 7800gaggcaaaac tggtttgacc gtgatcattt ttgtggtttt gaaaacaaat atacttgacc 7860cagtttcctt agttttttct tcaactgtcc ataggaacga taagtatttg aaagcaacat 7920caaatctata cgtttaaagc agggcagtta gcacaaattt gcaagtagaa cttctattag 7980cttatgccat agacatcacc caaccacttg tatgtgtgtg tgtatatata atatgcatat 8040atagttaccg tgctaaaatg gttaccagca ggttttgaga gagaatgctg catcagaaaa 8100gtgtcagttg ccacctcatt ctccctgatt taggttcctg acactgattc ctttctctct 8160cgtttttgac ccccattggg tgtatcttgt ctatgtacag atattttgta atatattaaa 8220tttttttctt tcagtttata aaaatggaaa gtggagattg gaaaattaaa tatttcctgt 8280tactatacca aaaaaaaaaa aaaaaaaaaa 8310272670DNAHomo sapiens 27ggttgggatc tgaggggtcc tctctgtgcc catcacagtt tgagcttcag ggaaaagaag 60aagaggtctt tgcccttcgt ttttccacgg gaggagaatc aagagtgagc catggagcta 120cgtgtgggga acaagtaccg cctgggacgg aagatcggga gcgggtcctt cggagatatc 180tacctgggtg ccaacatcgc ctctggtgag gaagtcgcca tcaagctgga gtgtgtgaag 240acaaagcacc cccagctgca catcgagagc aagttctaca agatgatgca gggtggcgtg 300gggatcccgt ccatcaagtg gtgcggagct gagggcgact acaacgtgat ggtcatggag 360ctgctggggc ctagcctcga ggacctgttc aacttctgtt cccgcaaatt cagcctcaag 420acggtgctgc tcttggccga ccagatgatc agccgcatcg agtatatcca ctccaagaac 480ttcatccacc gggacgtcaa gcccgacaac ttcctcatgg ggctggggaa gaagggcaac 540ctggtctaca tcatcgactt cggcctggcc aagaagtacc gggacgcccg cacccaccag 600cacattccct accgggaaaa caagaacctg accggcacgg cccgctacgc ttccatcaac 660acgcacctgg gcattgagca aagccgtcga gatgacctgg agagcctggg ctacgtgctc 720atgtacttca acctgggctc cctgccctgg caggggctca aagcagccac caagcgccag 780aagtatgaac ggatcagcga gaagaagatg tcaacgccca tcgaggtcct ctgcaaaggc 840tatccctccg aattctcaac atacctcaac ttctgccgct ccctgcggtt tgacgacaag 900cccgactact cttacctacg tcagctcttc cgcaacctct tccaccggca gggcttctcc 960tatgactacg tctttgactg gaacatgctg aaattcggtg cagcccggaa tcccgaggat 1020gtggaccggg agcggcgaga acacgaacgc gaggagagga tggggcagct acgggggtcc 1080gcgacccgag ccctgccccc tggcccaccc acgggggcca ctgccaaccg gctccgcagt 1140gccgccgagc ccgtggcttc cacgccagcc tcccgcatcc agccggctgg caatacttct 1200cccagagcga tctcgcgggt cgaccgggag aggaaggtga gtatgaggct gcacaggggt 1260gcgcccgcca acgtctcctc ctcagacctc actgggcggc aagaggtctc ccggatccca 1320gcctcacaga caagtgtgcc atttgaccat ctcgggaagt gaggagagcc cccattggac 1380cagtgtttgc ttagtgtctt cactgtattt tctttaaaaa aaaaaaaaaa aaaaaaaagg 1440caaaaataaa ccactcaaaa gaacaacaaa aaaacccagc acaaaaccga cgatggagtt 1500tgtttctttg atttctttgc caatggcaag aagatgagat gccctcagca ctgaggattc 1560ttgccccctt gtggtgcccg ctgcccccaa ccttcaggct gccagatgct cccctgacaa 1620caccaggcta caggagccag acgccagggc ctgcccggcc tcctgttcct gcccccaccc 1680accacctgcc tggagaggaa cgggtcgggt ccgtgtcgga gaagtgacag gtcccagagc 1740caaagccggc cctcaagcat catcagggag tggtgtagtc agttgaaggc agttcccacc 1800gagttttccg agcctcagaa tccaggagat acgcacagcc ccacccactc tgagatgaca 1860gtggctgact tcccgtgctg ggcttttcca ttgtccccct ggcctccagg ctcctcctct 1920gcctctccat ggagtgggtg gggaggtggt gggggccggc gtcccctgcg tgtgtgtgtg 1980tgtgtgtgtg tgtggatgta ttgacctgtg tttcccaaga cagcaggtgc cacggcccgc 2040cccgcctgcc agcccgaatt cccgttctcc tgtgtctact aacaaggaca tgggggtggg 2100cggtgacctc cgcatccctc agagctcaga gggtcctcgc tgccaccggt ccccccctag 2160cccgtcatca gccggtggca gctccatctt ccattcctgg ttttagggca gaatccatgg 2220agactgcttc cagaaggcat ctggctctga gttataaatt acttccctgg tcctgacagt 2280cacctggggt cccccctctc cctggttcca cctttctgag gaggagcctg gagtcagggc 2340tgggttttgg attaacccat ccttcctagt taacaccttt ttgtttttat tttattttat 2400ttttgtttgt tttctccgtg tgtgtgtttt cctaatttat ttacctctgt ttcccctttt 2460tccttttttt ttttaattaa agagcaaagc tttttattac tttgtaattt aaaaaactga 2520aaaaaaaaaa actgaagaac tttgggggga attttgtact tttttcctgt gtaaatattg 2580gacttttttg agctttatcg tggttgttaa tttgaagtaa taaagtagaa aagataaagt 2640gaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 2670283217DNAHomo sapiens 28tccctcgccc ggaggcagag atgcgctggc gcatcaccgc caggagccca cagtgaaaga 60ccatcggatg gaaggcgacg cccagaactc caggagaccg ctgtgggagg acgcgaggcc 120aggtgacgaa taggccaggc gtgagttccc aaacagcctc ctccccttca agagagtaag 180cttgggccac aggctgggac ggaagcagag gggcagacac gccaccaccc gcccggcctc 240gaacctacgg cggcacagtt cagcggaggc ggcccagcgg tcctgtcccg cgcctgcgca 300ctccaggccc cgccccgccc cgcgccctcc aggcccggcc cgccctccaa cctctgcgtg 360cgcacagcct agagcccgcc tccgtgaaag actgccgggc gcatgcggtc ggggttgttc 420actggctgtc cggggctccg cgcgcgtcgc cggcccagct ctgtcgctga cgggaggatc 480tgaagccggc cgcaggtcaa agagtaaaat gaagtacatt ctggttactg gtggtgttat 540atcaggaatt ggaaaaggaa tcattgccag cagtgtgggc acaatactca agtcatgtgg 600tttacatgta acttcaatca aaattgaccc ctacattaac attgatgcag gaacattctc 660tccttatgag catggtgagg tttttgtgct ggatgatggt ggggaagtag accttgacct 720gggtaactat gagcggttcc ttgacatccg cctcaccaag gacaataatc tgaccactgg 780aaagatatac cagtatgtca ttaacaagga acggaaagga gattacttgg ggaaaactgt 840ccaagttgtc cctcatatca cagatgcaat ccaggagtgg gtgatgagac aggcgttaat 900acctgtagat gaagatggcc tggaacctca agtgtgtgtt attgagcttg gtggaaccgt 960gggggacata gaaagcatgc cctttattga ggccttccgt cagttccaat tcaaggtcaa 1020aagagagaac ttttgtaaca tccacgtcag tctagttccc cagccaagtt caacagggga 1080acagaagact aaacctaccc agaatagtgt tcgggaactt agaggacttg ggctttcccc 1140agatctggtt gtatgcaggt gctcaaatcc acttgacaca tcagtgaagg agaaaatatc 1200aatgttctgc catgttgagc ctgaacaagt gatctgtgtc cacgatgtct catccatcta 1260ccgagtcccc ttgttgttag aggagcaagg ggttgtagat tattttcttc gaagacttga 1320ccttcctatt gagaggcagc caagaaaaat gctgatgaaa tggaaagaga tggctgacag 1380atatgatcgc ttgctggaga cctgctctat tgcccttgtg ggcaaataca cgaagttctc 1440agactcctat gcctctgtca ttaaggctct ggagcattct gcactggcca tcaaccacaa 1500attggaaatc aagtacatag attctgcgga cttggagccc atcacctcgc aagaagagcc 1560cgtgcgctac cacgaagctt ggcagaagct ctgtagtgct catggagtgc tggttccagg 1620aggatttggt gttcgaggaa cagaaggaaa aatccaagca attgcctggg ctcggaatca 1680gaaaaagcct tttttgggcg tgtgcttagg gatgcagttg gcagtggttg aattctcaag 1740aaacgtgctg ggatggcaag atgccaattc tacagagttt gaccctacga ccagtcatcc 1800cgtggtcgta gacatgccag aacacaaccc agggcagatg ggcggaacca tgaggctggg 1860caagaggaga accctgttcc agaccaagaa ctcagtcatg aggaaactct atggagacgc 1920agactacttg gaagagaggc accgccaccg atttgaggtg aatccagtct ggaaaaagtg 1980tttggaagaa caaggcttga agtttgttgg ccaagatgtt gaaggagaga gaatggaaat 2040tgtggagtta gaagatcatc ccttttttgt tggggttcag taccaccctg agttcctgtc 2100caggcctatc aagccctccc caccatactt tggcctcctc ctggcctctg tggggcggct 2160ctcacattac ctccagaaag gctgcaggct ctcacccagg gacacctata gtgacaggag 2220tggaagcagc tcccctgact ctgaaatcac cgaactgaag tttccatcaa taaatcatga 2280ctgatcttgt agcggatgat tcttcaagag acccttcaaa cttgggtaga gtttacagct 2340ctgactttac actcggcttt ggagactttc tttaaattat gtttttatta agattatttt 2400attatgcgga aaggtatttg ggaaacttgt cacttgcatg tcccatcacg tgtactggct 2460cctctgtggt gtctgcctgt tgcgtgacac tctccttgca gttcttgagt tgcggcagaa 2520catcgcgatg ggaaccgatg gtgggtgggg ctgcagagtg ccccatcggt caccttgttt 2580ctcaactacc tcgcatcatt gcagatgcta gcgcgttgcc tgtcgctttc ccttggatac 2640ctagaccgtt ataaagtgtg ccacatggac ttaccgagca tggagagagg attttagcta 2700ggatttgaac acttggtgct gggaacctca gggtattgct tgccactaag ccatgaaacc 2760agagacaaaa tctctatact gccctgagtt ggggggaatt ctcagtgcca actgtggctg 2820gtcctcattc aaagggacgg tcagtttggt gtcaacatga aacaccaaga tgtctgtctc 2880tgaagcgtga ttttaaaatc cccatgcctg tggctgcgct tcctatttct agggctggga 2940aacactcctt gcatcaaggg gtcacttaca gaacaaagaa tcttttgggg gaaacttcct 3000ctaaaaccct ctcatatata gacagctttg actggagggt ccatttttct tccaggatgg 3060tgttactgca gttgaaaggg caatatgaag ttactttctt aatgtgacct agcaataggc 3120atagctacgt ggcactatat tctggccaga ctcgatgtgt actctaactt aagaaataaa 3180tcagtaaggc agaacaagaa aaaaaaaaaa aaaaaaa 3217292141DNAHomo sapiens 29gcgcacgccg gccgcgccca cgtgaccggt ccgggtgcaa acacgcgggt cagctgatcc 60ggcccaactg cggcgtcatc ccggctataa gcgcacggcc tcggcgaccc tctccgaccc 120ggccgccgcc gccatgcagc cctccagcct tctgccgctc gccctctgcc tgctggctgc 180acccgcctcc gcgctcgtca ggatcccgct gcacaagttc acgtccatcc gccggaccat 240gtcggaggtt gggggctctg tggaggacct gattgccaaa ggccccgtct caaagtactc 300ccaggcggtg ccagccgtga ccgaggggcc cattcccgag gtgctcaaga actacatgga 360cgcccagtac tacggggaga ttggcatcgg gacgcccccc cagtgcttca cagtcgtctt 420cgacacgggc tcctccaacc tgtgggtccc ctccatccac tgcaaactgc tggacatcgc 480ttgctggatc caccacaagt acaacagcga caagtccagc acctacgtga agaatggtac 540ctcgtttgac atccactatg gctcgggcag cctctccggg tacctgagcc aggacactgt 600gtcggtgccc tgccagtcag cgtcgtcagc ctctgccctg ggcggtgtca aagtggagag 660gcaggtcttt ggggaggcca ccaagcagcc aggcatcacc ttcatcgcag ccaagttcga 720tggcatcctg ggcatggcct acccccgcat ctccgtcaac aacgtgctgc ccgtcttcga 780caacctgatg cagcagaagc tggtggacca gaacatcttc tccttctacc tgagcaggga 840cccagatgcg cagcctgggg gtgagctgat gctgggtggc acagactcca agtattacaa 900gggttctctg tcctacctga atgtcacccg caaggcctac tggcaggtcc acctggacca 960ggtggaggtg gccagcgggc tgaccctgtg caaggagggc tgtgaggcca ttgtggacac 1020aggcacttcc ctcatggtgg gcccggtgga tgaggtgcgc gagctgcaga aggccatcgg 1080ggccgtgccg ctgattcagg gcgagtacat gatcccctgt gagaaggtgt ccaccctgcc 1140cgcgatcaca ctgaagctgg gaggcaaagg ctacaagctg tccccagagg actacacgct 1200caaggtgtcg caggccggga agaccctctg cctgagcggc ttcatgggca tggacatccc 1260gccacccagc gggccactct ggatcctggg cgacgtcttc atcggccgct actacactgt 1320gtttgaccgt gacaacaaca gggtgggctt cgccgaggct gcccgcctct agttcccaag 1380gcgtccgcgc gccagcacag aaacagagga gagtcccaga gcaggaggcc cctggcccag 1440cggcccctcc cacacacacc cacacactcg cccgcccact gtcctgggcg ccctggaagc 1500cggcggccca agcccgactt gctgttttgt tctgtggttt tcccctccct gggttcagaa 1560atgctgcctg cctgtctgtc tctccatctg tttggtgggg gtagagctga tccagagcac 1620agatctgttt cgtgcattgg aagaccccac ccaagcttgg cagccgagct cgtgtatcct 1680ggggctccct tcatctccag ggagtcccct ccccggccct accagcgccc gctgggctga 1740gcccctaccc cacaccaggc cgtcctcccg ggccctccct tggaaacctg ccctgcctga 1800gggcccctct gcccagcttg ggcccagctg ggctctgcca ccctacctgt tcagtgtccc 1860gggcccgttg aggatgaggc cgctagaggc ctgaggatga gctggaagga gtgagagggg 1920acaaaaccca ccttgttgga gcctgcaggg tggtgctggg actgagccag tcccaggggc 1980atgtattggc ctggaggtgg ggttgggatt gggggctggt gccagccttc ctctgcagct 2040gacctctgtt gtcctcccct tgggcggctg agagccccag ctgacatgga aatacagttg 2100ttggcctccg gcctcccctc tgtaaaaaaa aaaaaaaaaa a 2141302964DNAHomo sapiens 30ggaaagagtg gtggcaggtg aagtcggaga cgacagagga actggtttcc tccgccccgc 60aaggcacaca gcctgccgac gccccattaa tacatgtgga aggggaaaga gactgaatgg 120aggaatgaat acaacttgat ccaggtcgtg cttcggaagc ggtcacttta cctgtgaacc 180tctctgcctg acaaacgggc aatgtacgga atcaaccacc aagatggcgg cgcccgtgaa 240gaatccgcaa ttaggtcgcc gtcatatgtc gcctaggaac gtacggaatt cgacccacgt 300acggaatcgg attccaagat gacggcatct atgaggaagt cacgcagtag gtgcagccat 360gttgcctgta cgtcgaggcc gtacaagcag ccgccgtacg gactctactg acaaggtggc 420ggcgccctcg ggaaagccac attagagcgc ggccatgttc ccggcgaaca tatggattcg 480gccaccatac ggatacgata agcaagatgg cggcgcctga ggggtcttgg gggctctagg 540ccggccacct actggtttgc agcggagacg acgcatgggg cctgcgcaat aggagtacgc 600tgcctgggag gcgtgactag aagcggaagt agttgtgggc gcctttgcaa ccgcctggga 660cgccgccgag tggtctgtgc aggttcgcgg gtcgctggcg ggggtcgtga gggagtgcgc 720cgggagcgga gatatggagg gagatggttc agacccagag cctccagatg ccggggagga 780cagcaagtcc gagaatgggg agaatgcgcc catctactgc atctgccgca aaccggacat 840caactgcttc atgatcgggt gtgacaactg caatgagtgg ttccatgggg actgcatccg 900gatcactgag aagatggcca aggccatccg ggagtggtac tgtcgggagt gcagagagaa 960agaccccaag ctagagattc gctatcggca caagaagtca cgggagcggg atggcaatga 1020gcgggacagc agtgagcccc gggatgaggg tggagggcgc aagaggcctg tccctgatcc 1080agacctgcag cgccgggcag ggtcagggac aggggttggg gccatgcttg ctcggggctc 1140tgcttcgccc cacaaatcct ctccgcagcc cttggtggcc acacccagcc agcatcacca 1200gcagcagcag cagcagatca aacggtcagc ccgcatgtgt ggtgagtgtg aggcatgtcg 1260gcgcactgag gactgtggtc actgtgattt ctgtcgggac atgaagaagt tcgggggccc 1320caacaagatc cggcagaagt gccggctgcg ccagtgccag ctgcgggccc gggaatcgta 1380caagtacttc ccttcctcgc tctcaccagt gacgccctca gagtccctgc caaggccccg 1440ccggccactg cccacccaac agcagccaca gccatcacag aagttagggc gcatccgtga 1500agatgagggg gcagtggcgt catcaacagt caaggagcct cctgaggcta cagccacacc 1560tgagccactc tcagatgagg acctacctct ggatcctgac ctgtatcagg acttctgtgc 1620aggggccttt gatgaccatg gcctgccctg gatgagcgac acagaagagt ccccattcct 1680ggaccccgcg ctgcggaaga gggcagtgaa agtgaagcat gtgaagcgtc gggagaagaa 1740gtctgagaag aagaaggagg agcgatacaa gcggcatcgg cagaagcaga agcacaagga 1800taaatggaaa cacccagaga gggctgatgc caaggaccct gcgtcactgc cccagtgcct 1860ggggcccggc tgtgtgcgcc ccgcccagcc cagctccaag tattgctcag atgactgtgg 1920catgaagctg gcagccaacc gcatctacga gatcctcccc cagcgcatcc agcagtggca 1980gcagagccct tgcattgctg aagagcacgg caagaagctg ctcgaacgca ttcgccgaga 2040gcagcagagt gcccgcactc gccttcagga aatggaacgc cgattccatg agcttgaggc 2100catcattcta cgtgccaagc agcaggctgt gcgcgaggat gaggagagca acgagggtga 2160cagtgatgac acagacctgc agatcttctg tgtttcctgt gggcacccca tcaacccacg 2220tgttgccttg cgccacatgg agcgctgcta cgccaagtat gagagccaga cgtcctttgg 2280gtccatgtac cccacacgca ttgaaggggc cacacgactc ttctgtgatg tgtataatcc 2340tcagagcaaa acatactgta agcggctcca ggtgctgtgc cccgagcact cacgggaccc 2400caaagtgcca gctgacgagg tatgcgggtg cccccttgta cgtgatgtct ttgagctcac 2460gggtgacttc tgccgcctgc ccaagcgcca gtgcaatcgc cattactgct gggagaagct 2520gcggcgtgcg gaagtggact tggagcgcgt gcgtgtgtgg tacaagctgg acgagctgtt

2580tgagcaggag cgcaatgtgc gcacagccat gacaaaccgc gcgggattgc tggccctgat 2640gctgcaccag acgatccagc acgatcccct cactaccgac ctgcgctcca gtgccgaccg 2700ctgagcctcc tggcccggac cccttacacc ctgcattcca gatgggggag ccgcccggtg 2760cccgtgtgtc cgttcctcca ctcatctgtt tctccggttc tccctgtgcc catccaccgg 2820ttgaccgccc atctgccttt atcagaggga ctgtccccgt cgacatgttc agtgcctggt 2880ggggctgcgg agtccactca tccttgcctc ctctccctgg gttttgttaa taaaattttg 2940aagaaaccaa ggaaaaaaaa aaaa 2964311870DNAHomo sapiens 31ctccgagacg ggtggggccg gagctccaag ctggtttgaa caagccctgg gcatgtttgg 60cgggaagttg gcttagctcg gctacctgtg gccccgcagt tttgtagtcc ccgccttgtt 120tctccccaga ggcctctcaa tcctccctcc atgatcttcg catagagcac agtacccctt 180cacacggagg acgcgatggc tcccaagaaa cgcccagaaa cccagaagac ctccgagatt 240gtattacgcc ccaggaacaa gaggagcagg agtcccctgg agctggagcc cgaggccaag 300aagctctgtg cgaagggctc cggtcctagc agaagatgtg actcagactg cctctgggtg 360gggctggctg gcccacagat cctgccacca tgccgcagca tcgtcaggac cctccaccag 420cataagctgg gcagagcttc ctggccatct gtccagcagg ggctccagca gtcctttttg 480cacactctgg attcttaccg gatattacaa aaggctgccc cctttgacag gagggctaca 540tccttggcgt ggcacccaac tcaccccagc accgtggctg tgggttccaa agggggagat 600atcatgctct ggaattttgg catcaaggac aaacccacct tcatcaaagg gattggagct 660ggagggagca tcactgggct gaagtttaac cctctcaata ccaaccagtt ttacgcctcc 720tcaatggagg gaacaactag gctgcaagac tttaaaggca acattctacg agtttttgcc 780agctcagaca ccatcaacat ctggttttgt agcctggatg tgtctgctag tagccgaatg 840gtggtcacag gagacaacgt ggggaacgtg atcctgctga acatggacgg caaagagctt 900tggaatctca gaatgcacaa aaagaaagtg acgcatgtgg ccctgaaccc atgctgtgat 960tggttcctgg ccacagcctc cgtagatcaa acagtgaaaa tttgggacct gcgccaggtt 1020agagggaaag ccagcttcct ctactcgctg ccgcacaggc atcctgtcaa cgcagcttgt 1080ttcagtcccg atggagcccg gctcctgacc acggaccaga agagcgagat ccgagtttac 1140tctgcttccc agtgggactg ccccctgggc ctgatcccgc accctcaccg tcacttccag 1200cacctcacac ccatcaaggc agcctggcat cctcgctaca acctcattgt tgtgggccga 1260tacccagatc ctaatttcaa aagttgtacc ccttatgaat tgaggacgat cgacgtgttc 1320gatggaaact cagggaagat gatgtgtcag ctctatgacc cagaatcttc tggcatcagt 1380tcgcttaatg aattcaatcc catgggggac acgctggcct ctgcaatggg ttaccacatt 1440ctcatctgga gccaggagga agccaggaca cggaagtgag agacactaaa gaaggtgtgg 1500gccagacaag gccttggagc ccacacatgg gatcaagtcc tgcaagcaga ggtggcgatt 1560tgttaaaggg ccaaaagtat ccaaggttag ggttggagca ggggtgctgg gacctggggc 1620actgtgggac tgggacactt ttatgttaat gctctggact tgcctccaga gactgctcca 1680gagttggtga cacagctgtc ccaagggccc ctctgtatct agcctggaac caaggttatc 1740ttggaactaa atgacttttc tcctctcagt gggtggtagc agagggatca agcagttatt 1800tgatttgtgc tcacttttga tatggccaat aaaaccatac cgactgagaa aaaaaaaaaa 1860aaaaaaaaaa 1870325335DNAHomo sapiens 32gcttctctcc atcttgtgat tcctttttcc tcctgaaccc tccagtgggg gtgcgagttt 60gtctttatca ccccccatcc caccgccttc ttttcttctc gctctcctac ccctccccag 120cttggtgggc gcctctttcc tttctcgccc cctttcattt ttatttattc atatttattt 180ggcgcccgct ctctctctgt ccctttgcct gcctccctcc ctccggatcc ccgctctctc 240cccggagtgg cgcgtcgggg gctccgccgc tggccaggcg tgatgttgca cgtggagatg 300ttgacgctgg tgtttctggt gctctggatg tgtgtgttca gccaggaccc gggctccaag 360gccgtcgccg accgctacgc tgtctactgg aacagcagca accccagatt ccagaggggt 420gactaccata ttgatgtctg tatcaatgac tacctggatg ttttctgccc tcactatgag 480gactccgtcc cagaagataa gactgagcgc tatgtcctct acatggtgaa ctttgatggc 540tacagtgcct gcgaccacac ttccaaaggg ttcaagagat gggaatgtaa ccggcctcac 600tctccaaatg gaccgctgaa gttctctgaa aaattccagc tcttcactcc cttttctcta 660ggatttgaat tcaggccagg ccgagaatat ttctacatct cctctgcaat cccagataat 720ggaagaaggt cctgtctaaa gctcaaagtc tttgtgagac caacaaatag ctgtatgaaa 780actataggtg ttcatgatcg tgttttcgat gttaacgaca aagtagaaaa ttcattagaa 840ccagcagatg acaccgtaca tgagtcagcc gagccatccc gcggcgagaa cgcggcacaa 900acaccaagga tacccagccg ccttttggca atcctactgt tcctcctggc gatgcttttg 960acattatagc acagtctcct cccatcactt gtcacagaaa acatcagggt cttggaacac 1020cagagatcca cctaactgct catcctaaga agggacttgt tattgggttt tggcagatgt 1080cagatttttg ttttctttct ttcagcctga attctaagca acaacttcag gttgggggcc 1140taaacttgtt cctgcctccc tcaccccacc ccgccccacc cccagccctg gcccttggct 1200tctctcaccc ctcccaaatt aaatggactc cagatgaaaa tgccaaattg tcatagtgac 1260accagtggtt cgtcagctcc tgtgcattct cctctaagaa ctcacctccg ttagcgcact 1320gtgtcagcgg gctatggaca aggaagaata gtggcagatg cagccagcgc tggctagggc 1380tgggagggtt ttgctctcct atgcaatatt tatgccttct cattcagaac tgtaagatga 1440tcgcgcaggg catcatgtca ccatgtcagg tccggagggg aggtattaag aatagatacg 1500atattacacc atttcctata ggagtatgta aatgaacagg cttctaaaag gttgagacac 1560tggttttttt ttttaatatg actgtcttaa agcattcttg acagcaaaac ttgtgctctc 1620taaaagaagc cttttttttt tttctaggag gcaggttggg tgtggaatgc taatacagag 1680caggtgtgaa aacagagaaa actacaggtt tgctgggggt gtgtatgtgt gagtgcctct 1740aatttttttg gtgactgggc agtgcacacc agatattttt tctttgaata cagatcacca 1800tggtgctaca actttttttt tttttttttt tttttttttt ttttttttta agaaactcaa 1860agaggcattt ttatgaataa agtgaccttc cccaaggctg acaagccagg gttgatgagt 1920gcatagtgga atagctttgg atactcctct gggggatgac atgtaccaag gagaggaccg 1980cagtggccag aggagacatg atttggcttt gctggagcgc cagtgtgctg tggcctttcc 2040ccgcctccca ccctagtacc cacgttttgc tccacactcc ttgaccgcag gggctcggac 2100acaaacccct gtcaccagga gagtcagtca gcactacttg ggagggctaa agggaaattt 2160ggaaataaaa ttccaaagtt tggagtaaaa aaattcaagt gttgatttta tattctttcc 2220ctttctgaca cagcctaaag cgtaggggga acatgtgttt atctgtggga gataaacaag 2280atggagtccc aaagacttta acaaaatatt tttttaaaaa tccactagaa tagaaaatac 2340attatttaga tatactttat gctgagagtg agtatatatg cttgtcctat ttaaacttgt 2400gagaaaaagt ggtatccctt gatacattta gaaatatggg ggctatcttg tttcattgtg 2460ggggtggggc agaaggagaa taaatgcagg atgaccctgt tgaaggaatc ttagcatggc 2520caacagggga cgtttccagt cgattaccag gaaatgcaag ccttggggtt tctactggtg 2580gtggggctgt catgaacttt aaaatccaaa gcctagacaa ggaaaagtgt tagaccaatt 2640gaaaagcaat ccagcccttt tttttttttt ttttttggct ttgcacgaca tgtcaacaga 2700aaccatgcct ttcaatataa gaaataaatg tgatgatcat gtaaaatgtg aaaaattgaa 2760agcattccag caaaataaga attttttata tatttgtttt ttaagatgta tatgttaaaa 2820aaagagaagg tcgcattatg gacagacttc gtgaatggga atttgcttag aattgtgagt 2880agttctgaat tagaaaagta tgtgaaggaa aggcagctgt aaacgtattg tgccctggag 2940agttgtacac atgttgaaat gtaatctggg cttacctgat ccatttggag tggatgtcac 3000tgccgagtct gttctcacat ggaaccatgt gtgtggggtt gccagcctca cagatacaat 3060caatcctatt cccctctgac ataaggaact cctctggagt ggcagagtct tatcacagaa 3120ggcagccacc atttcaccaa aacaaaagtt cacggcattc aattcctttt tcctttagct 3180atttatatat gcagtactct cagtcatatg cagaaatact tttttttttt taattaatag 3240ttacaggctt gttggtccag tgggatttgg gtagggggag aaagatacct tctaaaatgg 3300atcaatagaa ccaaaataat acagcatgtt ctataaccac aaggaaatca aatgatcctg 3360tcatgattcc agttagtcat aactatgtta gcagtgctaa atgcatttta gaaatggtga 3420cttctgtggt tttcctagca tttgtctcta acaaatggtg aaataattac tcatggccct 3480ctctgccatt gtctttcatt ttttcacagt gaaattagac ccctttactt caccattctg 3540ccactgcaaa ttaagtataa agaaaatagc aagagtgtcc acaccagtag acagtaagct 3600tctctacctg taagtgatga aatcatagct aatgcacttg ccatggagtt ttcaagatga 3660ttggtgtcag acagttttca ctttgtttaa aaagtgttgg tggccttttg tggtggtgtt 3720acaatcctct gggggcttag gaggatgttg atgcaacttt tagaagcttt taatttcaaa 3780aacaactcaa aaatctgaag gacagtcata gctgccactc agccccagtt agtcaaaccc 3840cagtgacctt tgcccctggt tgccaagggc tttgcaacat caagcaggga aataaggatc 3900tgtctgttta gtggataccg tgtatccttt aatagaccag gtaacagttc gtgttagttt 3960agactattgt tttgtactgt actttcttgg gtggcagagg aaagaaaagt aaaacattaa 4020aaaaaaaaaa aaaactgcgt tctttaaatt ctgtattatt agcaacctct gttgtacata 4080gtgtttgata ataaagtatt aatttgattc ttatgtcttt tgtaagtgag aacaatagac 4140tttcaggata caaaacatgc attgaggctt tgaaacatcc aatgtgtacc atggctgaaa 4200aaaagagtca caagtggctg agacactgct ccatacagga ctcatgtgtg gtcattgccc 4260acccaatctt atgactccat catcttggga cctggaacaa catgactttt ttgatcgata 4320ttttgtcctc ggtgttttca aggtctgatg ttggagccct gtggcccacc ctcccttctc 4380caccagcatg ttggtttgaa aaggataggg aatttagaaa cagttctgta ctttggtttg 4440gtttggtttt ctgtttgtga ttgttttcat ggactgtttt attttttccc aggaagagtc 4500tttatcaata tcatgtgcag ctcactcatg gaaatggttg caaaccaatc agtgtaggaa 4560gcttaaatgg ggctgtttcc ctctctgtgt cgttgtgaaa ggaagagtca cacagtacct 4620gtggattttc agggactctg tttttctccg gtgccttagc aacggcagca gccatttgta 4680ttattttcaa ataattagaa aaacagtttt caactcctcc tttccattca ttgctctcag 4740agttgtggtc actgactttt cttttgaaaa ccgcctccac caacaccccc gtttgcctac 4800accacccccc ttttacttag tatgtttatt ttttgtgtgt ctcttgcctt cctcccacgt 4860tttatttccc ctcagagctg tgaatgggca ggtctgtctc tggtttggca tcactgagtt 4920tttcccatgc attggcccca gggctgctag gatgtgagac aaatctccct acaatgggct 4980tgctcccatt gtctgtacag tttaatagat gctggcatgt cggaggttac ccatgagtca 5040aaatccgctc tccatgctta ctcttgacac cccattgaag ccactcattg tgtgtgcgtc 5100tgggtgtgaa gtccagctcc gtgtggtcct gtgcttgtac tgccctgctt tgcagttcct 5160ttgcacttac tcatcgagtg ctgttttgaa atgctgacat tatataaacg taaaagaaaa 5220tgtaaaaaaa aaaaacccac acacaaacaa acccatacga tctgtatttg tatatacacg 5280tgtccgtaca agtataacta aataaaaatt aaagattttc atcattttaa ttgga 5335332109DNAHomo sapiens 33aaagtaccag ctggcgcctt ttaagagata caggtctgtg aagcaggcag gttgctcagc 60tgcccccgga gcggttcctc cacctgaggc agactccacg tcggctggca tgagccggcg 120cccctgcagc tgcgccctac ggccaccccg ctgctcctgc agcgccagcc ccagcgcagt 180gacagccgcc gggcgccctc gaccctcgga tagttgtaaa gaagaaagtt ctaccctttc 240tgtcaaaatg aagtgtgatt ttaattgtaa ccatgttcat tccggactta aactggtaaa 300acctgatgac attggaagac tagtttccta cacccctgca tatttggaag gttcctgtaa 360agactgcatt aaagactatg aaaggctgtc atgtattggg tcaccgattg tgagccctag 420gattgtacaa cttgaaactg aaagcaagcg cttgcataac aaggaaaatc aacatgtgca 480acagacactt aatagtacaa atgaaataga agcactagag accagtagac tttatgaaga 540cagtggctat tcctcatttt ctctacaaag tggcctcagt gaacatgaag aaggtagcct 600cctggaggag aatttcggtg acagtctaca atcctgcctg ctacaaatac aaagcccaga 660ccaatatccc aacaaaaact tgctgccagt tcttcatttt gaaaaagtgg tttgttcaac 720attaaaaaag aatgcaaaac gaaatcctaa agtagatcgg gagatgctga aggaaattat 780agccagagga aattttagac tgcagaatat aattggcaga aaaatgggcc tagaatgtgt 840agatattctc agcgaactct ttcgaagggg actcagacat gtcttagcaa ctattttagc 900acaactcagt gacatggact taatcaatgt gtctaaagtg agcacaactt ggaagaagat 960cctagaagat gataaggggg cattccagtt gtacagtaaa gcaatacaaa gagttaccga 1020aaacaacaat aaattttcac ctcatgcttc aaccagagaa tatgttatgt tcagaacccc 1080actggcttct gttcagaaat cagcagccca gacttctctc aaaaaagatg ctcaaaccaa 1140gttatccaat caaggtgatc agaaaggttc tacttatagt cgacacaatg aattctctga 1200ggttgccaag acattgaaaa agaacgaaag cctcaaagcc tgtattcgct gtaattcacc 1260tgcaaaatat gattgctatt tacaacgggc aacctgcaaa cgagaaggct gtggatttga 1320ttattgtacg aagtgtctct gtaattatca tactactaaa gactgttcag atggcaagct 1380cctcaaagcc agttgtaaaa taggtcccct gcctggtaca aagaaaagca aaaagaattt 1440acgaagattg tgatctctta ttaaatcaat tgttactgat catgaatgtt agttagaaaa 1500tgttaggttt taacttaaaa aaaattgtat tgtgattttc aattttatgt tgaaatcggt 1560gtagtatcct gaggtttttt tccccccaga agataaagag gatagacaac ctcttaaaat 1620atttttacaa tttaatgaga aaaagtttaa aattctcaat acaaatcaaa caatttaaat 1680attttaagaa aaaaggaaaa gtagatagtg atactgaggg taaaaaaaaa ttgattcaat 1740tttatggtaa aggaaaccca tgcaatttta cctagacagt cttaaatatg tctggttttc 1800catctgttag catttcagac attttatgtt cctcttactc aattgatacc aacagaaata 1860tcaacttctg gagtctatta aatgtgttgt cacctttcta aagctttttt tcattgtgtg 1920tatttcccaa gaaagtatcc tttgtaaaaa cttgcttgtt ttccttattt ctgaaatctg 1980ttttaatatt tttgtataca tgtaaatatt tctgtatttt ttatatgtca aagaatatgt 2040ctcttgtatg tacatataaa aataaatttt gctcaataaa attgtaagct taaaaaaaaa 2100aaaaaaaaa 2109343618DNAHomo sapiens 34cccagactcc agccctggac cgcgcatccc gagcccagcg cccagacaga gtgtccccac 60accctcctct gagacgccat gttcaactcg atgaccccac caccaatcag tagctatggc 120gagccctgct gtctccggcc cctccccagt cagggggccc ccagtgtggg gacagaagga 180ctgtctggcc cgcccttctg ccaccaagct aacctcatgt ccggccccca cagttatggg 240ccagccagag agaccaacag ctgcaccgag ggcccactct tttcttctcc ccggagtgca 300gtcaagttga ccaagaagcg ggcactgtcc atctcacctc tgtcggatgc cagcctggac 360ctgcagacgg ttatccgcac ctcacccagc tccctcgtag ctttcatcaa ctcgcgatgc 420acatctccag gaggctccta cggtcatctc tccattggca ccatgagccc atctctggga 480ttcccagccc agatgaatca ccaaaaaggg ccctcgcctt cctttggggt ccagccttgt 540ggtccccatg actctgcccg gggtgggatg atcccacatc ctcagtcccg gggacccttc 600ccaacttgcc agctgaagtc tgagctggac atgctggttg gcaagtgccg ggaggaaccc 660ttggaaggtg atatgtccag ccccaactcc acaggcatac aggatcccct gttggggatg 720ctggatgggc gggaggacct cgagagagag gagaagcgtg agcctgaatc tgtgtatgaa 780actgactgcc gttgggatgg ctgcagccag gaatttgact cccaagagca gctggtgcac 840cacatcaaca gcgagcacat ccacggggag cggaaggagt tcgtgtgcca ctgggggggc 900tgctccaggg agctgaggcc cttcaaagcc cagtacatgc tggtggttca catgcgcaga 960cacactggcg agaagccaca caagtgcacg tttgaagggt gccggaagtc atactcacgc 1020ctcgaaaacc tgaagacgca cctgcggtca cacacgggtg agaagccata catgtgtgag 1080cacgagggct gcagtaaagc cttcagcaat gccagtgacc gagccaagca ccagaatcgg 1140acccattcca atgagaagcc gtatgtatgt aagctccctg gctgcaccaa acgctataca 1200gatcctagct cgctgcgaaa acatgtcaag acagtgcatg gtcctgacgc ccatgtgacc 1260aaacggcacc gtggggatgg ccccctgcct cgggcaccat ccatttctac agtggagccc 1320aagagggagc gggaaggagg tcccatcagg gaggaaagca gactgactgt gccagagggt 1380gccatgaagc cacagccaag ccctggggcc cagtcatcct gcagcagtga ccactccccg 1440gcagggagtg cagccaatac agacagtggt gtggaaatga ctggcaatgc agggggcagc 1500actgaagacc tctccagctt ggacgaggga ccttgcattg ctggcactgg tctgtccact 1560cttcgccgcc ttgagaacct caggctggac cagctacatc aactccggcc aatagggacc 1620cggggtctca aactgcccag cttgtcccac accggtacca ctgtgtcccg ccgcgtgggc 1680cccccagtct ctcttgaacg ccgcagcagc agctccagca gcatcagctc tgcctatact 1740gtcagccgcc gctcctccct ggcctctcct ttcccccctg gctccccacc agagaatgga 1800gcatcctccc tgcctggcct tatgcctgcc cagcactacc tgcttcgggc aagatatgct 1860tcagccagag ggggtggtac ttcgcccact gcagcatcca gcctggatcg gataggtggt 1920cttcccatgc ctccttggag aagccgagcc gagtatccag gatacaaccc caatgcaggg 1980gtcacccgga gggccagtga cccagcccag gctgctgacc gtcctgctcc agctagagtc 2040cagaggttca agagcctggg ctgtgtccat accccaccca ctgtggcagg gggaggacag 2100aactttgatc cttacctccc aacctctgtc tactcaccac agccccccag catcactgag 2160aatgctgcca tggatgctag agggctacag gaagagccag aagttgggac ctccatggtg 2220ggcagtggtc tgaaccccta tatggacttc ccacctactg atactctggg atatggggga 2280cctgaagggg cagcagctga gccttatgga gcgaggggtc caggctctct gcctcttggg 2340cctggtccac ccaccaacta tggccccaac ccctgtcccc agcaggcctc atatcctgac 2400cccacccaag aaacatgggg tgagttccct tcccactctg ggctgtaccc aggccccaag 2460gctctaggtg gaacctacag ccagtgtcct cgacttgaac attatggaca agtgcaagtc 2520aagccagaac aggggtgccc agtggggtct gactccacag gactggcacc ctgcctcaat 2580gcccacccca gtgaggggcc cccacatcca cagcctctct tttcccatta cccccagccc 2640tctcctcccc aatatctcca gtcaggcccc tatacccagc caccccctga ttatcttcct 2700tcagaaccca ggccttgcct ggactttgat tcccccaccc attccacagg gcagctcaag 2760gctcagcttg tgtgtaatta tgttcaatct caacaggagc tactgtggga gggtgggggc 2820agggaagatg cccccgccca ggaaccttcc taccagagtc ccaagtttct ggggggttcc 2880caggttagcc caagccgtgc taaagctcca gtgaacacat atggacctgg ctttggaccc 2940aacttgccca atcacaagtc aggttcctat cccacccctt caccatgcca tgaaaatttt 3000gtagtggggg caaatagggc ttcacatagg gcagcagcac cacctcgact tctgccccca 3060ttgcccactt gctatgggcc tctcaaagtg ggaggcacaa accccagctg tggtcatcct 3120gaggtgggca ggctaggagg gggtcctgcc ttgtaccctc ctcccgaagg acaggtatgt 3180aaccccctgg actctcttga tcttgacaac actcagctgg actttgtggc tattctggat 3240gagccccagg ggctgagtcc tcctccttcc catgatcagc ggggcagctc tggacatacc 3300ccacctccct ctgggccccc caacatggct gtgggcaaca tgagtgtctt actgagatcc 3360ctacctgggg aaacagaatt cctcaactct agtgcctaaa gagtagggaa tctcatccat 3420cacagatcgc atttcctaag gggtttctat ccttccagaa aaattggggg agctgcagtc 3480ccatgcacaa gatgccccag ggatgggagg tatgggctgg gggctatgta tagtctgtat 3540acgttttgag gagaaatttg ataatgacac tgtttcctga taataaagga actgcatcag 3600aaaaaaaaaa aaaaaaaa 3618355843DNAHomo sapiens 35ttggttgctg gtccacttac aaacactttt catatttgta tgtctttcca atggttatcc 60tgttttgttc atttcaggca tatggccctg atcagattaa ctgacatgat gtatatgcaa 120agccttttga gttcttcaga aaaataaatt atcttattca agactgattg cttataagga 180acttattata gctaatatag taggcacaat tttttttttg taattctcct agatgagtca 240gaacttagtt ttgacgtagg taaaaatttt atggtcacaa atctcaggtg tgagaaaatc 300tctttccttg atactctata taaatagagg atataaatat ttcaagtctg gaagtagtga 360gagaagctgg taattctgga catatagtga cagtcaaaaa ggagctcagg tacaggactg 420gtctaagctg ctcaagattc aggagacagc cagtacacag agaagctgag gagatacata 480agatatatct aaaacattta tctaaccttc tgtggtaaca agctccttaa aggggctgga 540tgatgttgtg ttcacttttt atcaccagca aaggctaaga taatgtatat agtaaatatt 600tagtaactat ttattaaata aataaatatt taagacagaa taaacaagta taataaatga 660accaataaga atgcaccatc taagtcaaaa tagccacttt tatccttaac attgtacctg 720ctttggctgc tgcagaagca aacttgttgg cattagacaa atcaagctgg tgatttaata 780aattccaatg taagtcttac cagtattgat gaataactat ccagcactca ccatgaaagt 840taaagaaaca acacagaaaa agttcctaag tggtcccaat ttgaaatgat cagataacct 900ataaaagaac atattcatat tatactaaca taaacacata taaatgcact tacagcagtt 960acacagtatt ctcttcaata actagtttcc ttatgcatta atgtgtaata acagcaacta 1020caatatttag ataattataa aaaccaaggc aataatttaa aaactgatta accgttttac 1080tctaacttaa gcatggattg gatcagtaag attgattaat aaatttgaat gcagtcagtt 1140ggattgattc taatttaaag ttttaatttg ttgtagaata attttaagtg aatatatttg 1200tccagtgttc gagtgctcaa cagtgtgttt gaaaaggaaa acaaagaaat gtttttgaga 1260aatgtgttaa ttccttaaga caatggattt taattggatc tagttgtttt catttttctt 1320cattatcatt atacatctgt atgttggaca gaacactaac actaaatagt ttttagaaaa 1380attttttaaa gttatttaaa tcataatatc atgactgact tttaaattca aaattaggct 1440gtgactatcc ttcttcactt

aggaagagtg ttgtgaaagc cagaccatct gctgaggtgc 1500tacagttaca tgtggccctc agaatgcatt tggcctgctc tgttttagca ctctgttgga 1560ttaccaatac acaaaacaag ttaaccttga tctttcacat taagtatctc agggacaaaa 1620tttgacatac gtctaaacct gtgacgtttc catctaaaga aggcagaaat aaaacaggac 1680tttagattcg gttacaataa aatatcagat gcaccagaga cacaaggctt gaagctctgt 1740cctgggaaaa tatggcaaac agtgcctctc ctgaacagaa tcaaaatcac tgttcagcca 1800tcaacaacag catcccactg atgcagggca acctccccac tctgaccttg tctggaaaga 1860tccgagtgac ggttactttc ttcctttttc tgctctctgc gacctttaat gcttctttct 1920tgttgaaact tcagaagtgg acacagaaga aagagaaagg gaaaaagctc tcaagaatga 1980agctgctctt aaaacatctg accttagcca acctgttgga gactctgatt gtcatgccac 2040tggatgggat gtggaacatt acagtccaat ggtatgctgg agagttactc tgcaaagttc 2100tcagttatct aaagcttttc tccatgtatg ccccagcctt catgatggtg gtgatcagcc 2160tggaccgctc cctggctatc acgaggcccc tagctttgaa aagcaacagc aaagtcggac 2220agtccatggt tggcctggcc tggatcctca gtagtgtctt tgcaggacca cagttataca 2280tcttcaggat gattcatcta gcagacagct ctggacagac aaaagttttc tctcaatgtg 2340taacacactg cagtttttca caatggtggc atcaagcatt ttataacttt ttcaccttca 2400gctgcctctt catcatccct cttttcatca tgctgatctg caatgcaaaa atcatcttca 2460ccctgacacg ggtccttcat caggaccccc acgaactaca actgaatcag tccaagaaca 2520atataccaag agcacggctg aagactctaa aaatgacggt tgcatttgcc acttcattta 2580ctgtctgctg gactccctac tatgtcctag gaatttggta ttggtttgat cctgaaatgt 2640taaacaggtt gtcagaccca gtaaatcact tcttctttct ctttgccttt ttaaacccat 2700gctttgatcc acttatctat ggatattttt ctctgtgatt gatagactac acaagaagtc 2760atatgaagaa gggtaaggta atgaatctct ccatctggga atgattaaca caaatgttgg 2820agcatgttta catacaaaca aagtaggatt tacacttaag ttatcattct tttagaaact 2880cagtcttcag agcctcaatt attaaggaaa agtcttcagg aaaaatacta aaatattttc 2940tcttcctcat aagcttctaa attaatctct gccttttctg acctcatata acacattatg 3000taggtttctt atcactttct ctttgcataa taatgtacta atatttaaaa taccttcagc 3060ctaaggcaca aggatgccaa aaaaacaaag gtgagaaacc acaacacagg tctaaactca 3120gcatgctttg gtgagttttt ctccaaaagg ggcatattag caattagagt tgtatgctat 3180ataatacata gagcacagag ccctttgccc ataatatcaa ctttccctcc tatagttaaa 3240aagaaaaaaa atgaatctat ttttctcttt ggcttcaaaa gcattctgac atttggagga 3300gtcagtaacc aatcccacca accactccag caacctgaca agactatgag tagttctcct 3360tcatcctatt tatgtggtac aggttgtgaa gtatctctat ataaagggaa attttagagg 3420ggttaggatt tggacagggg tttagaacat tcctctaagc tatctagtct gtggagtttg 3480tggcaattaa ttgccataaa ataacaatgt ttccaaatgc aactaagaaa atactcatag 3540tgagtacgct ctatgcatag tatgacttct attttaatgt gaagaatttt ttgtctctct 3600cctgatctta ctaaatccat atttcataaa taactgagaa taattaaaac aaaattaagc 3660aaatgcacaa gcaaaaagat gcttgataca caaaaggaac tctggagaga aaactacagc 3720ttcagtctgt acagatcaaa gaagacagaa catgtcaggg gaaggaggga aagatcttga 3780tgcagggttt cttaacctgc agtctatgca caacactata tttccatgta atgtttttat 3840ttcagcccta tttgtattat tttgtgcatt taaaaaacac aatcttaagg ggatagacta 3900gactgccaca gcagcccatg gcacaactaa cacctactga tattcacatt aaatagtatg 3960gtttccaaaa tatgtctgca caacaagacc tctttatgta attcaggctt gtgtctacct 4020cttccatgaa aaatggaaag ggatgaaaat aatgggagta taatacccat ttaatgtgaa 4080aaacataaga gtcttaaaag aaattaagcc atttaacatt ttttaaatag gtaagatacc 4140attatattta tatgagctat gtactgccac aaaaaaagat gaaatgtaat ttctaaatac 4200tccaggtgtg tggtattatg gaaagcaaat tgccaactaa tggcacgtcc tttctttctt 4260tgattttctc ctctcatact tcagttttat agtgttgtgt tgttgttttt ttcatatcct 4320accttacttt ccaattctgt ctcaattgaa ctccctctgt ctactcactc tttcattcat 4380agcttctttt ccattaaact cataccttta attaaccaat tcatggccca gttctacagt 4440tgaattggac aaggctaaaa ttctgtagtg tgctaaaatg ctcaagttgg cacataaacc 4500cattccaaga ttttatagtt cttgtagata acacagggat gtagataagt tgaaacaaaa 4560ccagtgtcct ctaagtctct atcatatact tattcctaaa ctgataattc ttacttctgg 4620atttaaaatc aaaaataaca cacttgtaca gatacaatct aagggcttta tcacacacgt 4680gttaacgaat gtatctcagc ttggttcttc ttgtgtgctc attatggatc tctctgtctt 4740aggaattgcc tcaggcattt ttttttttta cacattaact aaagggctat tcgaaatctt 4800gactcagggg ttcttaacct acatttcatg caaaaaatat atatatttca atgtattttt 4860tattttagtc ctatttgtat tattttatgc atttaaaaac acagtcctga gagggatgga 4920ccagactgcc acagcagctc atagcacaaa aaaaggttaa gaagtcctag ttgactttgt 4980atatatataa agaaatctat tacaataaaa atataacata atctattcat ctatttatat 5040gcaaacataa aaatgtaaat attgaaacaa gattgcttca atatgcttat tgttttcaaa 5100ccaacaaact ctcttaaggt tcaatatgta ataaaaaaca taacacaaat aattattcta 5160tatgaatatt atggttcata aattataatg tataatctat acattataat gtaatatata 5220aactaaaatt tatggcacaa aagataaata tggctttgaa attaaagata ttccactcaa 5280cagacaatat ttcatatttg atattacaat catttatttt atgtcctatt ataataaaag 5340gtgaggactc cttgtaaaaa aggaaatgtt ccacagagtc aatctaatat atcagatatt 5400ggagattcta tcttggtttc tcttccttta cttagcctat aaaactagtt aaaaatggaa 5460tttcttttag caattcagtt tagtacagga gtgacattaa ctaatgacaa taaattaaac 5520aaagcctaca ttagttcaat ttaagcctat tcaacagaaa tatagaaata tagtagctaa 5580aaaaatactc tggggaaggt accacaaaca ttatctacca gggaacatag cataaattag 5640tctgaaattt cctgagagtg actttgtctt agaacttagg tggtagtcat gaagagataa 5700tgtttttagg cagttaaaat acttctagaa ctccatctat tttacctgtg gtccactttc 5760ctacattgaa ccaatgcctt gggcttctct aattactata cattgtgctc atatgaataa 5820aagaaatttt aaaagaaaaa aaa 5843362100DNAHomo sapiens 36acaggccaca ggccaagggc agcagtcagg cctgctctgt ctgtgaacgc tcccggcttg 60gcctcggctg atgggccctc acgcctgaag cgggcaggaa gctccgggat ggatttcggg 120tctttggaga ccgtggtggc caactctgcc ttcatcgccg cccgaggcag ctttgacggc 180agcagctccc aaccctcccg ggacaagaag tacctggcca agctcaagct gcccccgctg 240tccaagtgtg agtccctccg cgacagcctc agcctggagt ttgagagtgt gtgcttggag 300cagcccatcg gcaagaagct ctttcagcag ttcctacaat cggcagagaa gcacctgccg 360gccctggagc tctggaaaga catcgaggac tatgacacgg cagacaatga cctccagcca 420cagaaggccc agaccatcct ggcccagtac ctggaccccc aggccaaact cttctgcagc 480ttcctggatg aggggatagt ggcgaagttt aaggaggggc ctgtggagat ccaggacggg 540ctcttccagc ccctgctgca ggccaccctg gcacacctgg gccaagcccc cttccaggag 600tacctgggca gcctgtactt cctgaggttc ctgcagtgga agtggctgga agcccagccc 660atgggggagg actggttcct ggacttcagg gtcctgggga aagggggctt cggggaggtg 720tcggcctgcc agatgaaggc gaccggcaag ctgtatgcct gcaagaagct gaacaagaag 780cggctgaaga agaggaaggg ctaccagggt gctatggtgg agaagaagat tctgatgaaa 840gtacacagca ggttcatcgt gtctctggcc tatgcgtttg aaaccaaagc cgacctctgt 900ctggtgatga ccatcatgaa cggaggtgac atcaggtacc acatctacaa cgtgaatgag 960gagaaccctg gcttcccgga gccgcgcgcc ctcttctaca cggcgcagat catctgcggc 1020ctggagcacc tgcaccagag gcggatcgtc taccgcgacc tcaagcccga gaacgtgctg 1080ctggacaatg acggcaatgt ccggatctct gaccttgggc tggccgtgga gctgctggac 1140ggacagagca agaccaaggg ctacgcaggg accccaggtt tcatggcccc cgagctcctg 1200cagggcgagg agtacgactt ctccgtggac tactttgccc tgggggtcac cctgtatgag 1260atgattgcgg ccagaggacc cttccgagcc cgtggagaga aggtggagaa caaggagctg 1320aagcaccgga tcatctcaga gcccgtgaag taccctgata agttcagcca ggccagcaag 1380gacttctgcg aggcgctgct ggagaaggac ccggagaagc gcctggggtt cagagatgag 1440acctgcgaca agctccgtgc ccaccccctc ttcaaggacc ttaactggag gcagctggag 1500gctgggatgc tgatgccccc tttcatccca gactccaaaa ctgtctacgc aaaggatatt 1560caggacgtgg gtgccttttc caccgtcaaa ggtgtggcct ttgacaaaac agacacagaa 1620ttctttcagg aatttgccac tggcaactgc cccatcccct ggcaggagga gatgatcgag 1680acgggcatct ttggcgagct gaacgtgtgg cgctcggacg gtcagatgcc ggacgacatg 1740aagggcatct ccgggggctc cagctcctcg tccaagtcag ggatgtgtct ggtttcctag 1800gtgacgcccc agagtccacg tggaggaaaa ggacccatac ggctcgatgg gggccgcctg 1860cctccgtggt gccagcctgg ggtctgctag caaggggaca cgtggttccc tccacccagg 1920tccccatcac gccatctcct tgcggcccaa ggaggagaaa gccacgtcgg cctgagccgc 1980cagatgcaca tgctggtgcc gtgagccccc gactgcatat ttcacgtctt ttgctccatc 2040tcactgagaa gacataagat gctctccaga gggagtaagc caaaaatcta caaactctta 2100372797DNAHomo sapiens 37gtttgcgttt gaacctcttg gcgggtgccg gccatggcgg cttcgctccc gggacctggg 60agccggcttt tccgcacata tggggctgcg gacggcagga gacagcggcg gccgggccgg 120gaagccgcgc agtggttccc gccgcaggac cggaggcgtt tcttcaacag cagcggcagc 180agcgacgcca gcatcggcga cccctcgcag tccgacgatc ctgacgatcc cgacgacccc 240gacttccccg gcagcccggt gaggcggcgg cggaggcgtc ccggcggccg agtgcccaag 300gaccggccca gcctgaccgt gaccccaaag cgctggaagc tgcgagctcg cccaagccta 360accgtgaccc caagacgcct ggggctgcga gctcggcccc cgcagaagtg cagcacaccc 420tgcggcccgc tccgacttcc gcccttcccc agccgcgact ccggccgcct cagcccggac 480ctcagcgtgt gcggccagcc cagggacggc gacgagctgg gcatcagtgc ctccctgttc 540agctctctgg cctcgccctg ccccgggtcc ccaacgccaa gggacagtgt catctcgatc 600ggcacctccg cctgtctggt tgcagcctca gccgtcccga gcggcctcca cctcccagaa 660gtctccctgg accgagcatc tctcccctgc tcccaggagg aagcgacagg aggagccaag 720gacaccagga tggtccacca aacccgcgcc agcctcaggt cagttctctt tggccttatg 780aactcaggaa cccctgagga ttctgagttt cgggcagatg ggaagaatat gagagagtcc 840tgctgtaaaa ggaaactggt ggtgggaaat ggaccagagg gtccaggtct gtcaagcaca 900ggcaagagga gggccacagg ccaggactct tgtcaagaga gagggcttca agaggccgtc 960cggagagagc atcaggaggc cagtgttccc aagggccgca ttgtgccaag gggaatagac 1020aggctggaga gaactagatc aagccggaag agcaaacatc aggaggcaac ggaaacctct 1080ctcctccatt cccaccgctt taaaaagggc caaaagctgg gaaaagattc gttccccacc 1140caggacctga ctcctttaca gaatgtctgc ttttggacca aaaccagggc ttccttcagt 1200ttccacaaga agaaaattgt gactgatgtg tcagaggtct gcagcatcta taccactgcc 1260acttctctct ctggatccct cctatcagaa tgttcaaacc ggcctgtcat gaacagaaca 1320agtggtgctc cgtcctcttg gcactcctcc tctatgtatt tgctaagccc cttaaacact 1380ctaagtattt caaacaaaaa ggcatctgat gctgaaaagg tttatgggga atgcagtcag 1440aagggtcctg tcccctttag ccattgcctt cccacagaaa aactgcaacg ctgtgagaag 1500attggggaag gggtgtttgg cgaagtgttt caaacaattg ctgatcacac acccgtagcc 1560ataaaaatca ttgctattga aggaccagat ttagtcaatg gatcccatca gaaaaccttt 1620gaggaaatcc tgccagagat catcatctcc aaagagttga gcctcttatc cggtgaagtg 1680tgcaaccgca cagaaggctt tatcgggctg aactcagtgc actgtgtcca gggatcttac 1740cctcccttgc tcctcaaagc ctgggatcac tataattcaa ccaaaggctc tgcaaatgac 1800cggcctgatt tttttaaaga cgaccagctc ttcattgtgc tggaatttga gtttggaggg 1860attgacttag agcaaatgcg aaccaagttg tcttccttgg ctactgcaaa gagcattcta 1920caccagctca cagcctccct cgcagtggca gaggcatcac tgcgctttga gcaccgagac 1980ttacactggg ggaacgtgct cttaaagaaa accagcctca aaaaactcca ctacaccctc 2040aatgggaaga gcagcactat ccccagctgt gggttgcaag tgagcatcat tgactacacc 2100ctgtcgcgct tggaacggga tgggattgtg gttttctgtg acgtttccat ggatgaggac 2160ctgtttaccg gtgacggtga ctaccagttt gacatctaca ggctcatgaa gaaggagaat 2220aacaaccgct ggggtgaata tcacccttat agtaatgtgc tctggttaca ttacctgaca 2280gacaagatgc tgaaacaaat gaccttcaag actaaatgta acactcctgc catgaagcaa 2340attaagagaa aaatccagga gttccacagg acaatgctga acttcagctc tgccactgac 2400ttgctctgcc agcacagtct gtttaagtaa gctaaatgta tcttactgcc ccgaaatgag 2460aggagactgg tcttgaagcc tctggtgctg tttcaacctc catccccaca ggagggtgga 2520actcccattc tcacaggttt ccagtcagct tttcaaacaa gaattttgtt tccaaatgga 2580aactgaaata tttgttgaaa tgtttaaatt tgctgataac aaatgttctg aaagaagtaa 2640actagccggg cacagtggcg tgcgcctgta gtcccagcta ctcgggaggc tgaggcagga 2700ggatcgcttg agcccaagag ttcatatcta gcctggtcaa catagcaaga cccctgtctc 2760tattttttta aataaataaa ctacatgtga aaacaaa 2797381708DNAHomo sapiens 38ctcttctgaa ttctccattc tgggctcttg cctgtgaaat ctttctttgc tttccccatc 60ttttcctcgc attttttcac catctttccc tcaatctcca ggagccaatg cgagactttg 120gctccgatta agcgacggcc cgagactcgg ggtgcgcgag gaggatcgac agagtggtga 180tggagagcac cccttcaagg ggactgaacc gagtacacct acaatgcagg aatctgcagg 240aattcttagg gggcctgagc cctggggtat tggaccgatt gtatgggcac cctgccacat 300gtctggctgt cttcagggag ctcccatcct tggctaagaa ctgggtgatg cggatgctct 360ttctggagca gcctttgcca caggctgctg tagctctgtg ggtaaagaag gaattcagca 420aggctcagga ggaaagtaca gggctgctga gcggcctccg gatctggcac acacagctgc 480tcccaggcgg gctccagggc ctcatcctca accccatttt ccgccagaac ctccgcattg 540cccttctggg tggggggaag gcctggtctg atgacacaag tcagctggga ccagacaagc 600atgcccggga cgttccctcc cttgacaagt acgccgagga gcgatgggag gtggtcttgc 660acttcatggt gggctccccc agtgcagctg tcagccagga cttggctcag ctcctcagcc 720aggctgggct catgaagagt actgaacctg gagagccgcc ctgcattact tccgctggct 780tccagttcct gttgctggac accccggctc agctctggta ctttatgttg cagtatttgc 840agacagccca gagccggggc atggacctgg tagagattct ctccttcctc ttccagctca 900gcttctctac tctgggcaag gattactctg tggaaggtat gagtgattct ctgttgaact 960tcctgcaaca tctgcgtgag tttgggcttg ttttccagag gaagaggaaa tctcggcgtt 1020actaccccac acgcctggcc atcaatctct catcaggtgt ctctggagct gggggcactg 1080tgcatcagcc aggtttcatt gtcgtggaaa ccaattaccg actgtatgcc tacacggagt 1140cggagctgca gattgccctc attgccctct tctctgagat gctctatcgg ttccccaaca 1200tggtggtggc gcaggtgacc cgggagagtg tgcagcaggc aatcgccagt ggcatcacag 1260cccagcagat aatccatttc ctaaggacaa gagcccaccc agtgatgctc aaacagacac 1320ctgtgctgcc ccccaccatc accgaccaga tccggctctg ggagctggaa agggacagac 1380tccggttcac tgagggtgtc ctgtataacc agttcctgtc gcaagtggac tttgagctgc 1440tgctggccca cgcgcgggag ctgggcgtgc tcgtgttcga gaactcggcc aagcggctca 1500tggtggtgac cccggccggg cacagcgacg tcaagcgctt ttggaagcgg cagaaacata 1560gctcctgaga gcgcgggact tggacacgga cctcggcggg cgggactggg cggggcgggg 1620catcagaact caggtgtttt ttatttacgc gtcagggctt ttcttgttta ataaagttat 1680gatagctaaa aaaaaaaaaa aaaaaaaa 1708392168DNAHomo sapiens 39ggagttagcc tcgctcaggg cgcggctaag gcgcccagat ggcctgcggg cgccaccacg 60tccctggtcc cagctcggga gcacatcaga ggcttagagg cgagtgggaa gggactcaga 120cagtgcagga cgagaaacgc ccgcggcacc aaagcccctc agagcgtcgc ccccgcctct 180agttctagaa agtcagtttc ccggcactgg caccccggaa cctcaggggc tgccgagctg 240ggggggcgct caagctgcga ggatccgggc tgcccgcgag acgaggagcg ggcgcccagg 300atggggtgca tgaagtccaa gttcctccag gtcggaggca atacattctc aaaaactgaa 360accagcgcca gcccacactg tcctgtgtac gtgccggatc ccacatccac catcaagccg 420gggcctaata gccacaacag caacacacca ggaatcaggg aggcaggctc tgaggacatc 480atcgtggttg ccctgtatga ttacgaggcc attcaccacg aagacctcag cttccagaag 540ggggaccaga tggtggtcct agaggaatcc ggggagtggt ggaaggctcg atccctggcc 600acccggaagg agggctacat cccaagcaac tatgtcgccc gcgttgactc tctggagaca 660gaggagtggt ttttcaaggg catcagccgg aaggacgcag agcgccaact gctggctccc 720ggcaacatgc tgggctcctt catgatccgg gatagcgaga ccactaaagg aagctactct 780ttgtccgtgc gagactacga ccctcggcag ggagataccg tgaaacatta caagatccgg 840accctggaca acgggggctt ctacatatcc ccccgaagca ccttcagcac tctgcaggag 900ctggtggacc actacaagaa ggggaacgac gggctctgcc agaaactgtc ggtgccctgc 960atgtcttcca agccccagaa gccttgggag aaagatgcct gggagatccc tcgggaatcc 1020ctcaagctgg agaagaaact tggagctggg cagtttgggg aagtctggat ggccacctac 1080aacaagcaca ccaaggtggc agtgaagacg atgaagccag ggagcatgtc ggtggaggcc 1140ttcctggcag aggccaacgt gatgaaaact ctgcagcatg acaagctggt caaacttcat 1200gcggtggtca ccaaggagcc catctacatc atcacggagt tcatggccaa aggaagcttg 1260ctggactttc tgaaaagtga tgagggcagc aagcagccat tgccaaaact cattgacttc 1320tcagcccaga ttgcagaagg catggccttc atcgagcaga ggaactacat ccaccgagac 1380ctccgagctg ccaacatctt ggtctctgca tccctggtgt gtaagattgc tgactttggc 1440ctggcccggg tcattgagga caacgagtac acggctcggg aaggggccaa gttccccatc 1500aagtggacag ctcctgaagc catcaacttt ggctccttca ccatcaagtc agacgtctgg 1560tcctttggta tcctgctgat ggagatcgtc acctacggcc ggatccctta cccagggatg 1620tcaaaccctg aagtgatccg agctctggag cgtggatacc ggatgcctcg cccagagaac 1680tgcccagagg agctctacaa catcatgatg cgctgctgga aaaaccgtcc ggaggagcgg 1740ccgaccttcg aatacatcca gagtgtgctg gatgacttct acacggccac agagagccag 1800taccaacagc agccatgata gggaggacca gggcagggcc agggggtgcc caggtggtgg 1860ctgcaaggtg gctccagcac catccgccag ggcccacacc cccttcctac tcccagacac 1920ccaccctcgc ttcagccaca gtttcctcat ctgtccagtg ggtaggttgg actggaaaat 1980ctctttttga ctcttgcaat ccacaatctg acattctcag gaagccccca agttgatatt 2040tctatttcct ggaatggttg gattttagtt acagctgtga tttggaaggg aaactttcaa 2100aatagtgaaa tgaatattta aataaaagat ataaatgcca aagtctttac caaaaaaaaa 2160aaaaaaaa 2168403628DNAHomo sapiens 40aaaggcgggg aagggcgtgg tgggaagctc tgtccgcggt cgcgccagct gttccccggg 60cagggtcgcc tctaggtgct cacctccgcc acttcgccat ggcgggtcct ggcccgggcg 120cggtgctgga gtccccccgg cagctgctgg gccgcgtgcg cttcttggca gaggcagcgc 180ggagcctccg cgccgggcgg ccgctgccag cagcgctggc tttcgtgccg cgagaggtgc 240tctacaagct ttacaaggac ccagcgggac cgtcgcgcgt gcttctgccg gtgtgggagg 300cagagggcct ggggctgcgt gtgggcgccg caggcccagc ccccggtacc ggctccgggc 360ccctccgcgc cgcccgcgac agcattgagc tccggcgcgg cgcctgcgtg cgcaccacgg 420gcgaggagct gtgcaatggc cacgggctct gggtgaagct gacaaaggag cagctggcag 480agcacctggg cgactgcggg ctgcaggaag gctggctgct ggtgtgccgc ccggcggagg 540gcggagcccg cctggtaccc atcgacactc ccaaccacct ccagcggcag cagcagctct 600ttggcgtgga ttatcggccg gtgctcaggt gggaacaggt ggtggacctg acatactcac 660atcgcctggg atcgagacct cagccggcag aggcatacgc agaagctgta caaaggctac 720tctatgtacc cccgacatgg acctacgagt gcgacgagga cctgatccac ttcttgtatg 780accacctggg caaggaggat gagaacctgg gtagcgtgaa gcagtatgtg gagagcatag 840acgtttcctc ctacacggag gagttcaacg tgtcctgcct gacagacagc aatgccgata 900cctactggga gagcgatggg tcccagtgcc aacactgggt acggcttact atgaagaagg 960gcaccattgt caagaagctg ctactcacag tggataccac agatgacaac tttatgccaa 1020agcgggtggt ggtctatggg ggtgaagggg acaacctgaa gaagctgagt gacgtgagca 1080ttgacgagac cctcatcggg gatgtctgtg tcctggagga catgaccgtc cacctcccga 1140tcatcgagat ccgcatcgtg gagtgccgag atgatgggat tgatgttcgt ctccgagggg 1200tcaagatcaa gtcatctaga cagcgggaac tagggttgaa tgcagacctg ttccagccaa 1260ctagtctggt gcgatatcca cgcctagaag gcaccgaccc tgaagtactg taccgcagag 1320ctgtcctcct gcagagattc atcaagatcc tcgatagtgt cctgcaccac ctggtacctg 1380cctgggacca cacactgggc accttcagtg agattaagca agtgaagcag ttcctactgc 1440tgtcccgcca gcggccaggc ctggtggctc agtgcctgcg tgactctgag agcagcaagc 1500ccagcttcat gccacgccta tacatcaacc gccgtcttgc catggaacac cgtgcctgcc 1560cctctcgaga ccctgcctgc aagaatgcag tcttcaccca ggtatatgaa ggcctcaagc 1620cctctgacaa atatgaaaag cccctggact acaggtggcc

catgcgctat gaccagtggt 1680gggagtgtaa atttattgca gaaggcatca ttgaccaagg gggtggtttc cgggacagcc 1740tggcagatat gtcagaagag ctgtgcccta gctcagcgga tacccccgtg cccctgccct 1800tctttgtacg cacagccaac cagggcaatg gcactggtga ggctcgggac atgtatgtac 1860ccaacccctc ctgccgagac tttgccaagt atgaatggat cggacagctg atgggggctg 1920cccttcgggg taaggagttc ctggtcctgg ccctgcctgg ttttgtgtgg aagcagcttt 1980ctggtgagga ggtgagctgg agcaaggact tcccagctgt ggactctgtg ctggtgaagc 2040tcctggaagt gatggaagga atggacaagg agacgtttga gttcaagttt gggaaggaac 2100taacattcac cactgtactg agtgaccaac aggtggtgga gctgatccct gggggtgcag 2160gcatcgtcgt gggatatggg gaccgttctc gtttcatcca actggtccag aaggcacggc 2220tagaggagag caaggagcag gtggcagcta tgcaggcagg tctgctgaag gtggtaccac 2280aggctgtgct ggacttgctg acctggcaag agttggagaa gaaagtgtgt ggggatccag 2340aggtcactgt ggatgctctg cgcaagctca cccggtttga ggacttcgag ccatctgact 2400cgcgggtgca gtatttctgg gaggcactga acaacttcac caacgaggac cggagccgct 2460tcctgcgctt tgtcacgggc cgcagtcgcc tgccagcacg gatctacatc tacccagaca 2520agctgggcta cgagaccaca gacgcgctgc ccgagtcttc cacttgctcc agcaccctct 2580tcctgccaca ctatgccagt gccaaggtat gcgaggagaa gctccgctat gcggcctaca 2640actgcgtggc catcgacact gacatgagcc cttgggagga gtgaggcgtg ccgccggctg 2700tgggaccagc aagactgcac gtgtccctct tggccttgcc cagggcgaag acaccttccc 2760tgccctggtt tggctgacgt gctcagcaaa accccatgtg ccctgctcct gtgtgcagtt 2820ggggtagggg cagctggcat ggtcaggtaa cactagtggc ccagccccgc agacccacaa 2880gccctacccg tgctggggct tgcttcccga ggtatttcac ctcttaagag ggaatcttcc 2940acaagcccag cacaagctgc caggcctgag ctacttgaag ggggccatct aggtccccaa 3000cccatggact ttgcctccat tttcagctcc gccttttttc tcctattttc tctctggctt 3060tcttcagcca tgactcacaa ctaaaaacat aaaacactgg aggttagtgg aggcccctcc 3120ccaagcaggg agcctgggat gggcagggag tgatagccaa actccttggt cacctgctcc 3180aagaaggaag cagtagctga gcacctgccc tcacattctg ctcttttccc ctctccctcc 3240ataccagaga tgtggtgagc tctgttcttc taccaaccca gtctcaacac acaaagtgcc 3300accaccttcc ctgactcaga acccacatcc actcaatgtg aactctacta ccacgacctc 3360cccatattcc tcacttctcc atcacctcca gcctgactcc ctgtctgccc tttcaccccc 3420aagattttgc acaggttaag gccagttatg gcctttttga aatctgtaat agctcccctt 3480tccccaactc taaagcctag accttaaacc tgttcctaga gctatgcaca cccctgcccc 3540agtttaccgt tcctccctca gggcctccgt gacactccat gaaaagaagt tcttgcatac 3600cggaaagttg aataaatgga tgaattca 3628413729DNAHomo sapiens 41ggtcctaccc ggaagcgcgc ccgggctcct gcaggcgggg cgctgtgcgc gccgcgatcc 60ggtacgtggg cctccgggct gtcccctctg ggggcggcga tcctccctcc ggagcccccc 120ttcaaccctc ccggaagtga ggaccaggga tgctgtgctg ctctcccatg agccagtcac 180cgagtcggtc tgctgcagcc ctttctgaac ctctggccgt ctggatgctc cactgtgctt 240gccaagatga agtgcgtctt ggtggccact gagggcgcag aggtcctctt ctactggaca 300gatcaggagt ttgaagagag tctccggctg aagttcgggc agtcagagaa tgaggaagaa 360gagctccctg ccctggagga ccagctcagc accctcctag ccccggtcat catctcctcc 420atgacgatgc tggagaagct ctcggacacc tacacctgct tctccacgga aaatggcaac 480ttcctgtatg tccttcacct gtttggagaa tgcctgttca ttgccatcaa tggtgaccac 540accgagagcg agggggacct gcggcggaag ctgtatgtgc tcaagtacct gtttgaagtg 600cactttgggc tggtgactgt ggacggtcat cttatccgaa aggagctgcg gcccccagac 660ctggcgcagc gtgtccagct gtgggagcac ttccagagcc tgctgtggac ctacagccgc 720ctgcgggagc aggagcagtg cttcgccgtg gaggccctgg agcgactgat tcacccccag 780ctctgtgagc tgtgcataga ggcgctggag cggcacgtca tccaggctgt caacaccagc 840cccgagcggg gaggcgagga ggccctgcat gccttcctgc tcgtgcactc caagctgctg 900gcattctact ctagccacag tgccagctcc ctgcgcccgg ccgacctgct tgccctcatc 960ctcctggttc aggacctcta ccccagcgag agcacagcag aggacgacat tcagccttcc 1020ccgcggaggg cccggagcag ccagaacatc cccgtgcagc aggcctggag ccctcactcc 1080acgggcccaa ctggggggag ctctgcagag acggagacag acagcttctc cctccctgag 1140gagtacttca caccagctcc ttcccctggc gatcagagct caggtagcac catctggctg 1200gaggggggca ccccccccat ggatgccctt cagatagcag aggacaccct ccaaacactg 1260gttccccact gccctgtgcc ttccggcccc agaaggatct tcctggatgc caacgtgaag 1320gaaagctact gccccctagt gccccacacc atgtactgcc tgcccctgtg gcagggcatc 1380aacctggtgc tcctgaccag gagccccagc gcgcccctgg ccctggttct gtcccagctg 1440atggatggct tctccatgct ggagaagaag ctgaaggaag ggccggagcc cggggcctcc 1500ctgcgctccc agcccctcgt gggagacctg cgccagagga tggacaagtt tgtcaagaat 1560cgaggggcac aggagattca gagcacctgg ctggagttta aggccaaggc tttctccaaa 1620agtgagcccg gatcctcctg ggagctgctc caggcatgtg ggaagctgaa gcggcagctc 1680tgcgccatct accggctgaa ctttctgacc acagccccca gcaggggagg cccacacctg 1740ccccagcacc tgcaggacca agtgcagagg ctcatgcggg agaagctgac ggactggaag 1800gacttcttgc tggtgaagag caggaggaac atcaccatgg tgtcctacct agaagacttc 1860ccaggcttgg tgcacttcat ctatgtggac cgcaccactg ggcagatggt ggcgccttcc 1920ctcaactgca gtcaaaagac ctcgtcggag ttgggcaagg ggccgctggc tgcctttgtc 1980aaaactaagg tctggtctct gatccagctg gcgcgcagat acctgcagaa gggctacacc 2040acgctgctgt tccaggaggg ggatttctac tgctcctact tcctgtggtt cgagaatgac 2100atggggtaca aactccagat gatcgaggtg cccgtcctct ccgacgactc agtgcctatc 2160ggcatgctgg gaggagacta ctacaggaag ctcctgcgct actacagcaa gaaccgccca 2220accgaggctg tcaggtgcta cgagctgctg gccctgcacc tgtctgtcat ccccactgac 2280ctgctggtgc agcaggccgg ccagctggcc cggcgcctct gggaggcctc ccgtatcccc 2340ctgctctagg ccaaggtggc cgcagtctgc ctttgcatcc tgtcctccag ccacccttgc 2400ttgccactgt tccccatgac gagagcctcc tgtctgcagt ggccatcctg aggatagggc 2460agagtgccca gggtggcccc agggcttcta aaaccccacc tagaccaccc tccatgtcag 2520gtactgagca aggccccaga tccttctctc tggaggaaga gggaagccca ggggtcctgt 2580ttgtaaaaca acggtggcaa cagctcctct tccagagctg cctctgcctt tatcctggga 2640gatggggagg aagccccatc tctgctgttc cctgcgtgga ggaagcccac ccagcaagct 2700ctctcctacc ccaggtaaaa ggtgctcctt tgcctgggtt tgaattccag cgctgccact 2760tcctctctgc acctcctggc aagtttcttc tattccccac gtttaaagcg atggcacctc 2820cgtcccaggg tggtgtgagg attacccagt gtggtaggtg ctcaataaat gttggtcatt 2880gttatcactg aagcccaaca tgctagtgct tctagaccct tctgtcagtg ctgataagcc 2940cttgctaagt cccagcccct tcatgcttgg ctggcgtctg ccctagggct ggggttctca 3000agcccctggc cctggcccag agatttggat tcccttggcg gccgtggagc ccagcctttg 3060atgtctttca aagcttctgt ggtgcgccct ggattgagaa ccaccacccg aggggtacag 3120cccctctctt ccaaccgaga agttcctgtc ccagaatgga cccagggaca agagaccctg 3180agagccctgg gactgggagt gtctgctcct ctgaggccag gaggccggtg ctgggccaga 3240gaggacggcg tggcgaaagt cagcgtccac tgcagcacag gatcagatgg ccgtgtgctg 3300tgcatgcagg agcctcgcct tctgtgtctt tagtcttgag ccaaaatttg ctcaaagact 3360gatctcttcc ttgcagggaa cagctttggg gctgggggaa ctagaaccca catgttggtc 3420taaaccctga gaaggtggca gtgaggaagt atcccctcag gtgactggat ctgtgttcct 3480ccttaacatc atctgatgga atggcaatga aaagcgtgga ttgtggaaaa tacagaaaaa 3540cataaaggaa aaaactccaa tcccctgagc ccaccactgt tcaggacccc tgcttttgtc 3600acctactatt tccctttagt ttttagcagc ggctggatgt gatatgtcta gtttaaccag 3660tccccttgat ctttctatat aataaataac acaggagtga acatcctgaa tcagaaaaaa 3720aaaaaaaaa 3729422710DNAHomo sapiens 42gctcatcttc ctaccagaaa tcggcaagtc actgaccctc gtcccgcccc cgccattccc 60cgcctcctcc tgtcccgcag tcggcgtcca gcggctctgc ttgttcgtgt gtgtgtcgtt 120gcaggcctta ttcatgggct caccgctgag gttcgacggg cgggtggtac tggtcaccgg 180cgcgggggca ggattgggcc gagcctatgc cctggctttt gcagaaagag gagcgttagt 240tgttgtgaat gatttgggag gggacttcaa aggagttggt aaaggctcct tagctgctga 300taaggttgtt gaagaaataa gaaggagagg tggaaaagca gtggccaact atgattcagt 360ggaagaagga gagaaggttg tgaagacagc cctggatgct tttggaagaa tagatgttgt 420ggtcaacaat gctggaattc tgagggatcg ttcctttgct aggataagtg atgaagactg 480ggatataatc cacagagttc atttgcgggg ttcattccaa gtgacacggg cagcatggga 540acacatgaag aaacagaagt atggaaggat tattatgact tcatcagctt caggaatata 600tggcaacttt ggccaggcca attatagtgc tgcaaagttg ggtcttctgg gccttgcaaa 660ttctcttgca attgaaggca ggaaaagcaa cattcattgt aacaccattg ctcctaatgc 720gggatcacgg atgactcaga cagttatgcc tgaagatctt gtggaagccc tgaagccaga 780gtatgtggca cctcttgtcc tttggctttg tcacgagagt tgtgaggaga atggtggctt 840gtttgaggtt ggagcaggat ggattggaaa attacgctgg gagcggactc ttggagctat 900tgtaagacaa aagaatcacc caatgactcc tgaggcagtc aaggctaact ggaagaagat 960ctgtgacttt gagaatgcca gcaagcctca gagtatccaa gaatcaactg gcagtataat 1020tgaagttctg agtaaaatag attcagaagg aggagtttca gcaaatcata ctagtcgtgc 1080aacgtctaca gcaacatcag gatttgctgg agctattggc cagaaactcc ctccattttc 1140ttatgcttat acggaactgg aagctattat gtatgccctt ggagtgggag cgtcaatcaa 1200ggatccaaaa gatttgaaat ttatttatga aggaagttct gatttctcct gtttgcccac 1260cttcggagtt atcataggtc agaaatctat gatgggtgga ggattagcag aaattcctgg 1320actttcaatc aactttgcaa aggttcttca tggagagcag tacttagagt tatataaacc 1380acttcccaga gcaggaaaat taaaatgtga agcagttgtt gctgatgtcc tagataaagg 1440atccggtgta gtgattatta tggatgtcta ttcttattct gagaaggaac ttatatgcca 1500caatcagttc tctctctttc ttgttggctc tggaggcttt ggtggaaaac ggacatcaga 1560caaagtcaag gtagctgtag ccatacctaa tagacctcct gatgctgtac ttacagatac 1620cacctctctt aatcaggctg ctttgtaccg cctcagtgga gactggaatc ccttacacat 1680tgatcctaac tttgctagtc tagcaggttt tgacaagccc atattacatg gattatgtac 1740atttggattt tctgccaggc gtgtgttaca gcagtttgca gataatgatg tgtcaagatt 1800caaggcaatt aaggctcgtt ttgcaaaacc agtatatcca ggacaaactc tacaaactga 1860gatgtggaag gaaggaaaca gaattcattt tcaaaccaag gtccaagaaa ctggagacat 1920tgtcatttca aatgcatatg tggatcttgc accaacatct ggtacttcag ctaagacacc 1980ctctgagggc gggaagcttc agagtacctt tgtatttgag gaaataggac gccgcctaaa 2040ggatattggg cctgaggtgg tgaagaaagt aaatgctgta tttgagtggc atataaccaa 2100aggcggaaat attggggcta agtggactat tgacctgaaa agtggttctg gaaaagtgta 2160ccaaggccct gcaaaaggtg ctgctgatac aacaatcata ctttcagatg aagatttcat 2220ggaggtggtc ctgggcaagc ttgaccctca gaaggcattc tttagtggca ggctgaaggc 2280cagagggaac atcatgctga gccagaaact tcagatgatt cttaaagact acgccaagct 2340ctgaagggca cactacacta ttaataaaaa tggaatcatt aaatactctc ttcacccaaa 2400tatgcttgat tattctgcaa aagtgattag aactaagatg caggggaaat tgcttaacat 2460tttcagatat cagataactg cagattttca ttttctacta atttttcatg tatcattatt 2520tttacaagga actatatata agctagcaca taattatcct tctgttctta gatctgtatc 2580ttcataataa aaaattttgc ccaagtcctg tttccttaga atttgtgata gcattgataa 2640gttgaaagga aaattaaatc aataaaggcc tttgatacct ttgttaaaaa aaaaaaaaaa 2700aaaaaaaaaa 271043888DNAHomo sapiens 43gcatggcggc caccaggtgc ctgcgctggg gcctgagccg agccggagtc tggctgctcc 60caccgcccgc acggtgccca cgccgggcgc tgcacaagca gaaagacggc actgagttca 120agagcatcta cagcctggac aagctctacc ccgaatctca gggctcggac accgcctgga 180gggtcccgaa tggtgcaaag caagccgaca gtgacatccc tctagatcgc ttgacaatat 240cttattgtcg gagtagtggt cctggggggc agaatgtgaa caaagtgaat tccaaggcag 300aagtcaggtt ccatttggca actgccgagt ggatcgcgga gcccgtgcgg cagaagatag 360ccatcacgca taaaaacaag atcaacaggt taggagagtt gatccttacc tctgagagca 420gccgctatca gttccggaat ctggcagatt gcctgcagaa aattcgagac atgatcactg 480aggccagcca gacaccgaag gagccaacaa aagaagatgt taaacttcat agaatcagga 540tagaaaacat gaatcgggaa aggctgagac aaaagagaat tcattctgct gtaaagacaa 600gcaggagggt cgacatggac tgaaatcacc ctctgcagct gggagggctc ttctgggcgt 660ccgggcagct gcagctgaga ggactttcac accataagga gatttctgtt tttctttttg 720gctgttaatg cttgtctata acattggagc catcacaaga atgttcattt ggaatgaagg 780ctgcaggcac tggttgcaga cgtctttata ggcagtcacc atgttgtcaa accttaataa 840tgcacctcat gtattagtca caataaaaat cagaactcaa aaaaaaaa 888449093DNAHomo sapiens 44cgagcccagt cgagccgcgc tcacctcggg ctcccgctcc gtctccacct ccgcctttgc 60cctggcggcg cgaccccgtc ccgggcgcgg cccccagcag tcgcgcgccg ttagcctcgc 120gcccgccgcg cagtccgggc ccggcgcgat gggggccgcc gccggccgga gcccccacct 180ggggcccgcg cccgcccgcc gcccgcagcg ctctctgctc ctgctgcagc tgctgctgct 240cgtcgctgcc ccggggtcca cgcaggccca ggccgccccg ttccccgagc tgtgcagtta 300tacatgggaa gctgttgata ccaaaaataa tgtactttat aaaatcaaca tctgtggaag 360tgtggatatt gtccagtgcg ggccatcaag tgctgtttgt atgcacgact tgaagacacg 420cacttatcat tcagtgggtg actctgtttt gagaagtgca accagatctc tcctggaatt 480caacacaaca gtgagctgtg accagcaagg cacaaatcac agagtccaga gcagcattgc 540cttcctgtgt gggaaaaccc tgggaactcc tgaatttgta actgcaacag aatgtgtgca 600ctactttgag tggaggacca ctgcagcctg caagaaagac atatttaaag caaataagga 660ggtgccatgc tatgtgtttg atgaagagtt gaggaagcat gatctcaatc ctctgatcaa 720gcttagtggt gcctacttgg tggatgactc cgatccggac acttctctat tcatcaatgt 780ttgtagagac atagacacac tacgagaccc aggttcacag ctgcgggcct gtccccccgg 840cactgccgcc tgcctggtaa gaggacacca ggcgtttgat gttggccagc cccgggacgg 900actgaagctg gtgcgcaagg acaggcttgt cctgagttac gtgagggaag aggcaggaaa 960gctagacttt tgtgatggtc acagccctgc ggtgactatt acatttgttt gcccgtcgga 1020gcggagagag ggcaccattc ccaaactcac agctaaatcc aactgccgct atgaaattga 1080gtggattact gagtatgcct gccacagaga ttacctggaa agtaaaactt gttctctgag 1140cggcgagcag caggatgtct ccatagacct cacaccactt gcccagagcg gaggttcatc 1200ctatatttca gatggaaaag aatatttgtt ttatttgaat gtctgtggag aaactgaaat 1260acagttctgt aataaaaaac aagctgcagt ttgccaagtg aaaaagagcg atacctctca 1320agtcaaagca gcaggaagat accacaatca gaccctccga tattcggatg gagacctcac 1380cttgatatat tttggaggtg atgaatgcag ctcagggttt cagcggatga gcgtcataaa 1440ctttgagtgc aataaaaccg caggtaacga tgggaaagga actcctgtat tcacagggga 1500ggttgactgc acctacttct tcacatggga cacggaatac gcctgtgtta aggagaagga 1560agacctcctc tgcggtgcca ccgacgggaa gaagcgctat gacctgtccg cgctggtccg 1620ccatgcagaa ccagagcaga attgggaagc tgtggatggc agtcagacgg aaacagagaa 1680gaagcatttt ttcattaata tttgtcacag agtgctgcag gaaggcaagg cacgagggtg 1740tcccgaggac gcggcagtgt gtgcagtgga taaaaatgga agtaaaaatc tgggaaaatt 1800tatttcctct cccatgaaag agaaaggaaa cattcaactc tcttattcag atggtgatga 1860ttgtggtcat ggcaagaaaa ttaaaactaa tatcacactt gtatgcaagc caggtgatct 1920ggaaagtgca ccagtgttga gaacttctgg ggaaggcggt tgcttttatg agtttgagtg 1980gcacacagct gcggcctgtg tgctgtctaa gacagaaggg gagaactgca cggtctttga 2040ctcccaggca gggttttctt ttgacttatc acctctcaca aagaaaaatg gtgcctataa 2100agttgagaca aagaagtatg acttttatat aaatgtgtgt ggcccggtgt ctgtgagccc 2160ctgtcagcca gactcaggag cctgccaggt ggcaaaaagt gatgagaaga cttggaactt 2220gggtctgagt aatgcgaagc tttcatatta tgatgggatg atccaactga actacagagg 2280cggcacaccc tataacaatg aaagacacac accgagagct acgctcatca cctttctctg 2340tgatcgagac gcgggagtgg gcttccctga atatcaggaa gaggataact ccacctacaa 2400cttccggtgg tacaccagct atgcctgccc ggaggagccc ctggaatgcg tagtgaccga 2460cccctccacg ctggagcagt acgacctctc cagtctggca aaatctgaag gtggccttgg 2520aggaaactgg tatgccatgg acaactcagg ggaacatgtc acgtggagga aatactacat 2580taacgtgtgt cggcctctga atccagtgcc gggctgcaac cgatatgcat cggcttgcca 2640gatgaagtat gaaaaagatc agggctcctt cactgaagtg gtttccatca gtaacttggg 2700aatggcaaag accggcccgg tggttgagga cagcggcagc ctccttctgg aatacgtgaa 2760tgggtcggcc tgcaccacca gcgatggcag acagaccaca tataccacga ggatccatct 2820cgtctgctcc aggggcaggc tgaacagcca ccccatcttt tctctcaact gggagtgtgt 2880ggtcagtttc ctgtggaaca cagaggctgc ctgtcccatt cagacaacga cggatacaga 2940ccaggcttgc tctataaggg atcccaacag tggatttgtg tttaatctta atccgctaaa 3000cagttcgcaa ggatataacg tctctggcat tgggaagatt tttatgttta atgtctgcgg 3060cacaatgcct gtctgtggga ccatcctggg aaaacctgct tctggctgtg aggcagaaac 3120ccaaactgaa gagctcaaga attggaagcc agcaaggcca gtcggaattg agaaaagcct 3180ccagctgtcc acagagggct tcatcactct gacctacaaa gggcctctct ctgccaaagg 3240taccgctgat gcttttatcg tccgctttgt ttgcaatgat gatgtttact cagggcccct 3300caaattcctg catcaagata tcgactctgg gcaagggatc cgaaacactt actttgagtt 3360tgaaaccgcg ttggcctgtg ttccttctcc agtggactgc caagtcaccg acctggctgg 3420aaatgagtac gacctgactg gcctaagcac agtcaggaaa ccttggacgg ctgttgacac 3480ctctgtcgat gggagaaaga ggactttcta tttgagcgtt tgcaatcctc tcccttacat 3540tcctggatgc cagggcagcg cagtggggtc ttgcttagtg tcagaaggca atagctggaa 3600tctgggtgtg gtgcagatga gtccccaagc cgcggcgaat ggatctttga gcatcatgta 3660tgtcaacggt gacaagtgtg ggaaccagcg cttctccacc aggatcacgt ttgagtgtgc 3720tcagatatcg ggctcaccag catttcagct tcaggatggt tgtgagtacg tgtttatctg 3780gagaactgtg gaagcctgtc ccgttgtcag agtggaaggg gacaactgtg aggtgaaaga 3840cccaaggcat ggcaacttgt atgacctgaa gcccctgggc ctcaacgaca ccatcgtgag 3900cgctggcgaa tacacttatt acttccgggt ctgtgggaag ctttcctcag acgtctgccc 3960cacaagtgac aagtccaagg tggtctcctc atgtcaggaa aagcgggaac cgcagggatt 4020tcacaaagtg gcaggtctcc tgactcagaa gctaacttat gaaaatggct tgttaaaaat 4080gaacttcacg gggggggaca cttgccataa ggtttatcag cgctccacag ccatcttctt 4140ctactgtgac cgcggcaccc agcggccagt atttctaaag gagacttcag attgttccta 4200cttgtttgag tggcgaacgc agtatgcctg cccacctttc gatctgactg aatgttcatt 4260caaagatggg gctggcaact ccttcgacct ctcgtccctg tcaaggtaca gtgacaactg 4320ggaagccatc actgggacgg gggacccgga gcactacctc atcaatgtct gcaagtctct 4380ggccccgcag gctggcactg agccgtgccc tccagaagca gccgcgtgtc tgctgggtgg 4440ctccaagccc gtgaacctcg gcagggtaag ggacggacct cagtggagag atggcataat 4500tgtcctgaaa tacgttgatg gcgacttatg tccagatggg attcggaaaa agtcaaccac 4560catccgattc acctgcagcg agagccaagt gaactccagg cccatgttca tcagcgccgt 4620ggaggactgt gagtacacct ttgcctggcc cacagccaca gcctgtccca tgaagagcaa 4680cgagcatgat gactgccagg tcaccaaccc aagcacagga cacctgtttg atctgagctc 4740cttaagtggc agggcgggat tcacagctgc ttacagcgag aaggggttgg tttacatgag 4800catctgtggg gagaatgaaa actgccctcc tggcgtgggg gcctgctttg gacagaccag 4860gattagcgtg ggcaaggcca acaagaggct gagatacgtg gaccaggtcc tgcagctggt 4920gtacaaggat gggtcccctt gtccctccaa atccggcctg agctataaga gtgtgatcag 4980tttcgtgtgc aggcctgagg ccgggccaac caataggccc atgctcatct ccctggacaa 5040gcagacatgc actctcttct tctcctggca cacgccgctg gcctgcgagc aagcgaccga 5100atgttccgtg aggaatggaa gctctattgt tgacttgtct ccccttattc atcgcactgg 5160tggttatgag gcttatgatg agagtgagga tgatgcctcc gataccaacc ctgatttcta 5220catcaatatt tgtcagccac taaatcccat gcacggagtg ccctgtcctg ccggagccgc 5280tgtgtgcaaa gttcctattg atggtccccc catagatatc ggccgggtag caggaccacc 5340aatactcaat ccaatagcaa atgagattta cttgaatttt gaaagcagta ctccttgctt 5400agcggacaag catttcaact acacctcgct catcgcgttt cactgtaaga gaggtgtgag 5460catgggaacg cctaagctgt taaggaccag cgagtgcgac tttgtgttcg aatgggagac 5520tcctgtcgtc tgtcctgatg

aagtgaggat ggatggctgt accctgacag atgagcagct 5580cctctacagc ttcaacttgt ccagcctttc cacgagcacc tttaaggtga ctcgcgactc 5640gcgcacctac agcgttgggg tgtgcacctt tgcagtcggg ccagaacaag gaggctgtaa 5700ggacggagga gtctgtctgc tctcaggcac caagggggca tcctttggac ggctgcaatc 5760aatgaaactg gattacaggc accaggatga agcggtcgtt ttaagttacg tgaatggtga 5820tcgttgccct ccagaaaccg atgacggcgt cccctgtgtc ttccccttca tattcaatgg 5880gaagagctac gaggagtgca tcatagagag cagggcgaag ctgtggtgta gcacaactgc 5940ggactacgac agagaccacg agtggggctt ctgcagacac tcaaacagct accggacatc 6000cagcatcata tttaagtgtg atgaagatga ggacattggg aggccacaag tcttcagtga 6060agtgcgtggg tgtgatgtga catttgagtg gaaaacaaaa gttgtctgcc ctccaaagaa 6120gttggagtgc aaattcgtcc agaaacacaa aacctacgac ctgcggctgc tctcctctct 6180caccgggtcc tggtccctgg tccacaacgg agtctcgtac tatataaatc tgtgccagaa 6240aatatataaa gggcccctgg gctgctctga aagggccagc atttgcagaa ggaccacaac 6300tggtgacgtc caggtcctgg gactcgttca cacgcagaag ctgggtgtca taggtgacaa 6360agttgttgtc acgtactcca aaggttatcc gtgtggtgga aataagaccg catcctccgt 6420gatagaattg acctgtacaa agacggtggg cagacctgca ttcaagaggt ttgatatcga 6480cagctgcact tactacttca gctgggactc ccgggctgcc tgcgccgtga agcctcagga 6540ggtgcagatg gtgaatggga ccatcaccaa ccctataaat ggcaagagct tcagcctcgg 6600agatatttat tttaagctgt tcagagcctc tggggacatg aggaccaatg gggacaacta 6660cctgtatgag atccaacttt cctccatcac aagctccaga aacccggcgt gctctggagc 6720caacatatgc caggtgaagc ccaacgatca gcacttcagt cggaaagttg gaacctctga 6780caagaccaag tactaccttc aagacggcga tctcgatgtc gtgtttgcct cttcctctaa 6840gtgcggaaag gataagacca agtctgtttc ttccaccatc ttcttccact gtgaccctct 6900ggtggaggac gggatccccg agttcagtca cgagactgcc gactgccagt acctcttctc 6960ttggtacacc tcagccgtgt gtcctctggg ggtgggcttt gacagcgaga atcccgggga 7020cgacgggcag atgcacaagg ggctgtcaga acggagccag gcagtcggcg cggtgctcag 7080cctgctgctg gtggcgctca cctgctgcct gctggccctg ttgctctaca agaaggagag 7140gagggaaaca gtgataagta agctgaccac ttgctgtagg agaagttcca acgtgtccta 7200caaatactca aaggtgaata aggaagaaga gacagatgag aatgaaacag agtggctgat 7260ggaagagatc cagctgcctc ctccacggca gggaaaggaa gggcaggaga acggccatat 7320taccaccaag tcagtgaaag ccctcagctc cctgcatggg gatgaccagg acagtgagga 7380tgaggttctg accatcccag aggtgaaagt tcactcgggc aggggagctg gggcagagag 7440ctcccaccca gtgagaaacg cacagagcaa tgcccttcag gagcgtgagg acgatagggt 7500ggggctggtc aggggtgaga aggcgaggaa agggaagtcc agctctgcac agcagaagac 7560agtgagctcc accaagctgg tgtccttcca tgacgacagc gacgaggacc tcttacacat 7620ctgactccgc agtgcctgca ggggagcacg gagccgcggg acagccaagc acctccaacc 7680aaataagact tccactcgat gatgcttcta taattttgcc tttaacagaa actttcaaaa 7740gggaagagtt tttgtgatgg gggagagggt gaaggaggtc aggccccact ccttcctgat 7800tgtttacagt cattggaata aggcatggct cagatcggcc acagggcggt accttgtgcc 7860cagggttttg ccccaagtcc tcatttaaaa gcataaggcc ggacgcatct caaaacagag 7920ggctgcattc gaagaaaccc ttgctgcttt agtcccgata gggtatttga ccccgatata 7980ttttagcatt ttaattctct ccccctattt attgactttg acaattactc aggtttgaga 8040aaaaggaaaa aaaaacagcc accgtttctt cctgccagca ggggtgtgat gtaccagttt 8100gtccatcttg agatggtgag gctgtcagtg tatggggcag cttccggcgg gatgttgaac 8160tggtcattaa tgtgtcccct gagttggagc tcattctgtc tcttttctct tttgctttct 8220gtttcttaag ggcacacaca cgtgcgtgcg agcacacaca cacatacgtg cacagggtcc 8280ccgagtgcct aggttttgga gagtttgcct gttctatgcc tttagtcagg aatggctgca 8340cctttttgca tgatatcttc aagcctgggc gtacagagca catttgtcag tatttttgcc 8400ggctggtgaa ttcaaacaac ctgcccaaag attgatttgt gtgtttgtgt gtgtgtgtgt 8460gtgtgtgtgt gtgtgtgtga gtggagttga ggtgtcagag aaaatgaatt ttttccagat 8520ttggggtata ggtctcatct cttcaggttc tcatgatacc acctttactg tgcttatttt 8580tttaagaaaa aagtgttgat caaccattcg acctataaga agccttaatt tgcacagtgt 8640gtgacttaca gaaactgcat gaaaaatcat gggccagagc ctcggcccta gcattgcact 8700tggcctcatg ctggagggag gctgggcggg tacagcgcgg aggaggaggg aggccaggcg 8760ggcatggcgt ggaggaggag ggaggccggg cggtcacagc atggaggagg agggaggcgc 8820tgctggtgtt cttattctgg cggcagcgcc tttcctgcca tgtttagtga atgacttttc 8880tcgcattgta gaattgtata tagactctgg tgttctattg ctgagaagca aaccgccctg 8940cagcatccct cagcctgtac cggtttggct ggcttgtttg atttcaacat gagtgtattt 9000tttaaaattg atttttctct tcattttttt ttcaatcaac tttactgtaa tataaagtat 9060tcaacaattt caataaaaga taaattatta aaa 9093457014DNAHomo sapiens 45cggggaccgc gacgagcccg ggtcgccgtt ggcagcagca gcagcaacac cagcagcagc 60agcagccccg gcggcggcgc ggaccccgag cgcccgggcg caccccggct tcccggagcg 120cgacgcggcg gcagcagccc cggtgcggcc gcgcgcgcct taggctcggc cccgcggctc 180ggggaccccg actcccggcc cagcgagcgc gtcccccggc gccgcccgag agcccgagga 240ggcagcggcc gcaggcagcc ggggaggggg gcggccaccg cccgcgccgg gcatcctcag 300gagccccaga gcgcggaggg cgcggcgccg ccgagcggtg ctggcccccg cgggcctccc 360cggaccttcc ccaccgcctg ggcccgaggg acgcgtgatc gggcgggcgg ccgggcgcaa 420gggtgggagg gagccgcccc cgcccgcgcc ccctccgccc ctcgccccaa cccctgggcg 480ccgggcccgg gccgcgcggc ctgaagcgcc cgcgatggcg agcccgccgc ggcacgggcc 540gcccgggccg gcgagcggag acggccccaa cctcaacaac aacaacaaca acaacaacca 600cagcgtgcgc aagtgcggct acctgcgcaa gcagaagcat ggccacaagc gcttcttcgt 660gctgcgcgga cccggcgcgg gcggcgacga ggcgacggcg ggcggggggt cggcgccgca 720accgccgcgg ctcgagtact acgagagcga gaaaaagtgg cggagcaagg caggcgcgcc 780gaaacgggtg atcgctctcg actgctgcct gaacatcaac aagcgcgccg acgccaagca 840caagtacctg atcgccctct acaccaagga cgagtacttc gccgtggccg ccgagaacga 900gcaggagcag gagggctggt accgcgcgct caccgacctg gtcagcgagg gccgcgcggc 960cgccggagac gcgccccccg ccgccgcgcc cgccgcgtcc tgcagcgcct ccctgcccgg 1020cgccctgggc ggctctgccg gcgccgccgg ggccgaggac agctacgggc tggtggctcc 1080cgccacggcc gcctaccgtg aggtgtggca ggtgaacctg aagcccaagg gtctgggcca 1140gagcaagaac ctgacggggg tgtaccgtct gtgcctgtct gcgcgcacca tcggcttcgt 1200gaagctcaac tgcgagcagc cgtcggtgac gctgcagctc atgaacatcc gccgctgcgg 1260ccactcggac agcttcttct tcatcgaggt gggccgctcg gccgtcacag gccccggcga 1320gctgtggatg caggcggacg actcggtggt ggcgcagaac atccacgaga ccatcctgga 1380ggccatgaag gcgctcaagg agctcttcga gttccggccg cgcagtaaga gccaatcgtc 1440ggggtcgtcg gccacgcacc ccatcagcgt ccccggcgcg cgccgccacc accacctggt 1500caacctgccc cccagccaga cgggcctggt gcgccgctcg cgcaccgaca gcctggccgc 1560caccccgccg gcggccaagt gcagctcgtg ccgggtgcgc accgccagcg agggcgacgg 1620cggcgcggcg gcgggagcgg cggccgcggg cgccaggccg gtgtcggtgg ctgggagccc 1680cctgagcccc gggccggtgc gcgcgcccct gagccgctcg cacaccctga gcggcggctg 1740cggcggccgc gggagcaagg tggcgctgct gccggcaggg ggcgcgctgc aacacagccg 1800ctccatgtcc atgcccgtgg cgcactcgcc gcccgccgcc accagccccg gctccctgtc 1860gtccagcagc ggccacggct cgggctccta cccgccgccg cccggcccgc acccgcctct 1920gccgcatccg ctgcaccacg gccccggcca gcggccctcc agcggcagcg cctccgcctc 1980gggctccccc agcgaccccg gcttcatgtc cctggacgag tacggctcca gcccaggcga 2040cctgcgcgcc ttctgcagcc accgaagcaa cacgcccgag tccatcgcgg agacgccccc 2100ggcccgagac ggcggcggcg gcggtgagtt ctacgggtac atgaccatgg acaggcccct 2160gagccactgt ggccgctcct accgccgggt ctcgggggac gcggcccagg acctggaccg 2220agggctgcgc aagaggacct actccctgac cacgccagcc cggcagcggc cggtgcccca 2280gccctcctct gcctcgctgg atgaatacac cctgatgcgg gccaccttct cgggcagcgc 2340gggccgcctc tgcccgtcct gccccgcgtc ctctcccaag gtggcctacc acccctaccc 2400agaggactac ggagacatcg agatcggctc ccacaggagc tccagcagca acctgggggc 2460agacgacggc tacatgccca tgacgcccgg cgcggccctc gcgggcagtg ggagcggcag 2520ctgcaggagc gacgactaca tgcccatgag ccccgccagc gtgtccgccc ccaagcagat 2580cttgcagccc agggccgccg ccgccgccgc cgccgccgtg ccttctgcgg ggcctgcggg 2640gccagcaccc acctctgcgg cgggcaggac attcccggcg agcgggggcg gctacaaggc 2700cagctcgccc gccgagagct cccccgagga cagtgggtac atgcgcatgt ggtgcggttc 2760caagctgtcc atggagcatg cagatggcaa gctgctgccc aacggggact acctcaacgt 2820gtcccccagc gacgcggtca ccacgggcac cccgcccgac ttcttctccg cagccctgca 2880ccccggcggg gagccgctca ggggcgttcc cggctgctgc tacagctcct tgccccgctc 2940ctacaaggcc ccctacacct gtggcgggga cagcgaccag tacgtgctca tgagctcccc 3000cgtggggcgc atcctggagg aggagcgtct ggagcctcag gccacgccag ggcccagcca 3060ggcggccagc gccttcgggg ccggccccac gcagccccct caccctgtag tgccttcgcc 3120cgtgcggcct agcggcggcc gcccggaggg cttcttgggc cagcgcggcc gggcggtgag 3180gcccacgcgc ctgtccctgg aggggctgcc cagcctgccc agcatgcacg agtacccact 3240gccaccggag cccaagagcc ccggcgagta catcaacatc gactttggcg agcccggggc 3300ccgcctgtcg ccgcccgcgc ctcccctgct ggcgtcggcg gcctcgtcct cctcgctctt 3360gtccgccagc agcccggcct cgtcgctggg ctcaggcacc ccgggcacca gcagcgacag 3420ccggcagcgg tctccgctct ccgactacat gaacctcgac ttcagctccc ccaagtctcc 3480taagccgggc gccccgagcg gccaccccgt gggctccttg gacggcctcc tgtcccccga 3540ggcctcctcc ccgtatccgc cgttgccccc gcgtccgtcc gcgtccccgt cgtcgtctct 3600gcagccgccg ccaccgccgc cggccccggg ggagctgtac cgcctgcccc ccgcctcggc 3660cgttgccacc gcccagggcc cgggcgccgc ctcatcgttg tcctcggaca ccggggacaa 3720tggtgactac accgagatgg cttttggtgt ggccgccacc ccgccgcaac ctatcgcggc 3780ccccccgaag ccagaagctg cccgcgtggc cagcccgacg tcgggcgtga agaggctgag 3840cctcatggag caggtgtcgg gagtcgaggc cttcctgcag gccagccagc ccccggaccc 3900ccaccgcggc gccaaggtca tccgcgcaga cccgcagggg ggccgccgcc gccacagttc 3960cgagaccttc tcctccacca cgacggtcac ccccgtgtcc ccgtccttcg cccacaaccc 4020caagcgccac aactcggcct ccgtggaaaa tgtctctctc aggaaaagca gcgagggcgg 4080cgtgggtgtc ggccctggag ggggcgacga gccgcccacc tccccacgac agttgcagcc 4140ggcgccccct ttggcaccgc agggccggcc gtggaccccg ggtcagcccg ggggcttggt 4200cggttgtcct gggagcggtg gatcgcccat gcgcagagag acctctgccg gcttccagaa 4260tggtctcaac tacatcgcca tcgacgtgag ggaggagccc gggctgccac cccagccgca 4320gccgccgccg ccgccgcttc ctcagccggg agacaagagc tcctggggcc ggacccgaag 4380cctcgggggt ctcatcagcg ctgtgggcgt cggcagcacc ggcggcgggt gcggggggcc 4440gggtcccggt gccctgcccc ctgccaacac ctacgccagc attgacttct tgtcccacca 4500cttgaaggag gccaccatcg tgaaagagtg aagatctgtc tggctttatc accaggatgt 4560cacatgtcag agagtatcat taaaagaaga cgctcagcac tgtttcagcc cgaagctgct 4620tgcagttttc ttttggatct gagcaatgac tgtgtttgga aacatctgtg gactctgtta 4680gatgaggcac caacaaggca aggtcacctg cctctttccc ttgttcccgg atggggcatt 4740catcattgtg ctgtttgcgt tttgttttgt tttgttttaa caaaattagc tgaagaagtt 4800attctcaaga aaattggatg ttttcattgg ccttcttaaa ttgtggccag tgtcttttaa 4860tttcttcttc ttttcctttt ggcaaagcag atataaccct cagcatgcta ggagagtgca 4920cccgtaccta tggaagtggt aaaatctggt atttactggc ttacactcaa aacgaccaca 4980gtcctacctc agttcaaggt aaagccggat ttccgtggcg ggggtcccac aggacctcct 5040gtagtagccc ctgcgctgtg tgtctggagc gcggtcctcg gccttattga aatggtccaa 5100gtagacagct gcttgttgga ttccagtgca ggtacctgcg atgtttacgt ccacaccgag 5160cccagtgtgg gactgacatt tctcaatgga agtgaaattt gggattggac tttgaagacg 5220gattactaaa taataattat tatatgtaac tgaagcaacc tacttttgaa aatcaactgt 5280attgggtagt gggaggtggg agggaagggc tttgggaagg ggatgaatat ctctttttac 5340ctttaacaga cttgtttaat cttctcgatg tagatgttta tgtaggtact tcacattgca 5400aacgcctttt attctattta caagctcaga tgtctctgct ctcctgaatc ttgggcatgc 5460ctttctgtaa ccaaaaatcc ctgtaggcgt gctagcaatt ccagggtggt ccgggtttgg 5520cagatttgat ttttaaaaaa cgtattatct ttaataaaat gttattatgt caaccagtga 5580ggctgccctg aacaaaaaaa acaaaaagaa aaaaaaaaaa ggaaagaaag aaactgataa 5640aaagaggcat tccagcccct atgttattga tggaaaaaga aaaagaagaa aagcaatctc 5700gcagtacatg ttacttgtcg aaaaaattcc ggacaagact acccttgttt tatgttttca 5760gtattctgaa aataccagtg tgtggcagtt ctcgcagatg ttacctaaaa ctgctgaact 5820tgaccggcag aatgttctgc cgttttctgc tccctcgaca cttgattgga gggctgtcga 5880cctctcctcc cgtgggggct tccccagtgc ctatcttctc tgatagtcat ggagaggtta 5940cactaattca ttggagatgt aagttgttgg ttttgttttg ttttgttttt agaaaaatat 6000atataaatat ataatagata tctatcgcta tagaataatg cattaataaa atgaggcttt 6060tttagaggaa gaccaaaaaa ttcaatgtct taaaaatata tttaatggca atgcaaaagt 6120cttcctgctt ccgtgctgaa ctttagaaca gaggattgta ttgcaagaca aagttgaatg 6180taaagtgatc tccctgaaca tttttaaggt tttacttttc tgaaattata catcacagca 6240gtgcataggc catataatgt tagctggaag gtcaatttca gtgtatgata tactttatta 6300agatgtataa aaatcctgaa gtttttattt agttttggga ataggcatca atgggtggta 6360tttgctttgt aactcccccc aggtacgata gggactgaat atggaccctg ctgaaagcag 6420tgtattgacg catatttaac tcgccctcta tccgtagagt agtcatgaca ctatacagat 6480ggttcgtgtt catactgcag cttaaaacaa gcaaaataca cagatgataa tatgctaaat 6540tttcctctat cctgtacatt tcacaaaaag gcatatgcaa tatttacatt tttaatttag 6600tttacagaat ggaaccaaaa tgtataaatg ttatgtttgc taaaacttca caatgtatat 6660tgggtctttg tacattttgc ctgacttacc ttaaatttaa aatatttttt gctatataaa 6720ctttaacagt tattaaacag tgttttcttt ttgggtacgt attgtttctg gatatcaaga 6780tgttaaatat atttcttgct attgtgatat gacaagagac ttaacttatc ttgctctgtc 6840ttccactgta cacgctgtat ataggggtca atgtgatgct gctggagacg agaataaact 6900ggactagaat agtgcattgt atttagtctg tattgatcat ggatgccctc cttaatagcc 6960atatgcaata aaataaagta cattatttat gaaatgaaaa aaaaaaaaaa aaaa 7014463392DNAHomo sapiens 46gcggagccag cccctcccct acccggagca gcccgctggg gccgtcccga gcggcgacac 60actaggagtc ccggccggcc agccagggca gccgcggtcc cgggactcgg ccgtgagtgc 120tgcgggacgg atggtggcgg cggggcgcgg gccagcgcgg gcgccgtgag ccggagctgc 180gcgcggggca tgcggctgcg gcccccggcc ctcggccccc gcgctccggc cccagccccg 240gccgccggcc cccgcggagt gcagcgaccg cgccgccgct gagggaggcg ccccaccatg 300ccgcgggccc cggcgccgct gtacgcctgc ctcctggggc tctgcgcgct cctgccccgg 360ctcgcaggtc tcaacatatg cactagtgga agtgccacct catgtgaaga atgtctgcta 420atccacccaa aatgtgcctg gtgctccaaa gaggacttcg gaagcccacg gtccatcacc 480tctcggtgtg atctgagggc aaaccttgtc aaaaatggct gtggaggtga gatagagagc 540ccagccagca gcttccatgt cctgaggagc ctgcccctca gcagcaaggg ttcgggctct 600gcaggctggg acgtcattca gatgacacca caggagattg ccgtgaacct ccggcccggt 660gacaagacca ccttccagct acaggttcgc caggtggagg actatcctgt ggacctgtac 720tacctgatgg acctctccct gtccatgaag gatgacttgg acaatatccg gagcctgggc 780accaaactcg cggaggagat gaggaagctc accagcaact tccggttggg atttgggtct 840tttgttgata aggacatctc tcctttctcc tacacggcac cgaggtacca gaccaatccg 900tgcattggtt acaagttgtt tccaaattgc gtcccctcct ttgggttccg ccatctgctg 960cctctcacag acagagtgga cagcttcaat gaggaagttc ggaaacagag ggtgtcccgg 1020aaccgagatg cccctgaggg gggctttgat gcagtactcc aggcagccgt ctgcaaggag 1080aagattggct ggcgaaagga tgcactgcat ttgctggtgt tcacaacaga tgatgtgccc 1140cacatcgcat tggatggaaa attgggaggc ctggtgcagc cacacgatgg ccagtgccac 1200ctgaacgagg ccaacgagta cactgcatcc aaccagatgg actatccatc ccttgccttg 1260cttggagaga aattggcaga gaacaacatc aacctcatct ttgcagtgac aaaaaaccat 1320tatatgctgt acaagaattt tacagccctg atacctggaa caacggtgga gattttagat 1380ggagactcca aaaatattat tcaactgatt attaatgcat acaatagtat ccggtctaaa 1440gtggagttgt cagtctggga tcagcctgag gatcttaatc tcttctttac tgctacctgc 1500caagatgggg tatcctatcc tggtcagagg aagtgtgagg gtctgaagat tggggacacg 1560gcatcttttg aagtatcatt ggaggcccga agctgtccca gcagacacac ggagcatgtg 1620tttgccctgc ggccggtggg attccgggac agcctggagg tgggggtcac ctacaactgc 1680acgtgcggct gcagcgtggg gctggaaccc aacagtgcca ggtgcaacgg gagcgggacc 1740tatgtctgcg gcctgtgtga gtgcagcccc ggctacctgg gcaccaggtg cgagtgccag 1800gatggggaga accagagcgt gtaccagaac ctgtgccggg aggcagaggg caagccactg 1860tgcagcgggc gtggggactg cagctgcaac cagtgctcct gcttcgagag cgagttcggc 1920aagatctatg ggcctttctg tgagtgcgac aacttctcct gtgccaggaa caagggagtc 1980ctctgctcag gccatggcga gtgtcactgc ggggaatgca agtgccatgc aggttacatc 2040ggggacaact gtaactgctc gacagacatc agcacatgcc ggggcagaga tggccagatc 2100tgcagcgagc gtgggcactg tctctgtggg cagtgccaat gcacggagcc gggggccttt 2160ggggagatgt gtgagaagtg ccccacctgc ccggatgcat gcagcaccaa gagagattgc 2220gtcgagtgcc tgctgctcca ctctgggaaa cctgacaacc agacctgcca cagcctatgc 2280agggatgagg tgatcacatg ggtggacacc atcgtgaaag atgaccagga ggctgtgcta 2340tgtttctaca aaaccgccaa ggactgcgtc atgatgttca cctatgtgga gctccccagt 2400gggaagtcca acctgaccgt cctcagggag ccagagtgtg gaaacacccc caacgccatg 2460accatcctcc tggctgtggt cggtagcatc ctccttgttg ggcttgcact cctggctatc 2520tggaagctgc ttgtcaccat ccacgaccgg agggagtttg caaagtttca gagcgagcga 2580tccagggccc gctatgaaat ggcttcaaat ccattataca gaaagcctat ctccacgcac 2640actgtggact tcaccttcaa caagttcaac aaatcctaca atggcactgt ggactgatgt 2700ttccttctcc gaggggctgg agcggggatc tgatgaaaag gtcagactga aacgccttgc 2760acggctgctc ggcttgatca cagctcccta ggtaggcacc acagagaaga ccttctagtg 2820agcctgggcc aggagcccac agtgcctgta caggaaggtg cctggccatg tcacctggct 2880gctaggccag agccatgcca ggctgcgtcc ctccgagctt gggataaagc aaggggacct 2940tggcactctc agctttccct gccacatcca gcttgttgtc ccaatgaaat actgagatgc 3000tgggctgtct ctcccttcca ggaatgctgg gcccccagcc tggccagaca agacgactgt 3060caggaagggt cggagtctgt aaaaccagca tacagtttgg cttttttcac attgatcatt 3120tttatatgaa ataaaaagat cctgcattta tggtgtagtt ctgagtcctg agacttttcc 3180gcgtgatggc tatgccttgc acacaggtgt tggtgatggg gctgttgaga tgcctgttga 3240aggtacatcg tttgcaaatg tcagtttcct ctcctgtccg tgtttgttta gtacttttat 3300aatgaaaaga aacaagattg tttgggattg gaagtaaaga ttaaaaccaa aagaatttgt 3360gtttgtctga taaaaaaaaa aaaaaaaaaa aa 3392473463DNAHomo sapiens 47aatgaaacga agcgctgagg aaagtggctt gggtttgaat attgtggttg agtctgaagc 60gctgggaggc ggacattaaa gtgaagtggt tgcggtaacc tggcctgggc ctgaagtgag 120tgagaggcac atgaagagaa gtattcaagt atttatacag ataggaatca agataatcaa 180caatgtctgt cactgaggaa gacctgtgcc accatatgaa agtagtagtt cgtgtacgtc 240cggaaaacac taaagaaaaa gcagctggat ttcataaagt ggttcatgtt gtggataaac 300atatcctagt ttttgatccc aaacaagaag aagtcagttt tttccatgga aagaaaacta 360caaatcaaaa tgttataaag aaacaaaata aggatcttaa atttgtattt gatgctgttt 420ttgatgaaac gtcaactcag tcagaagttt ttgaacacac tactaagcca attcttcgta 480gttttttgaa tggatataat tgcacagtac ttgcctatgg tgccactggt gctgggaaga 540cccacactat gctaggatca gctgatgaac ctggagtgat gtatctaaca atgttacacc 600tttacaaatg catggatgag attaaagaag agaaaatatg tagtactgca gtttcatatc 660tggaggtata taatgaacag attcgtgatc tcttagtaaa ttcagggcca cttgctgtcc 720gggaagatac ccaaaaaggg gtggtcgttc atggacttac tttacaccag cccaaatcct 780cagaagaaat tttacattta ttggataatg gaaacaaaaa caggacacaa catcccactg 840atatgaatgc cacatcttct cgttctcatg ctgttttcca aatttacttg cgacaacaag 900acaaaacagc aagtatcaat caaaatgtcc gtattgccaa gatgtcactc attgacctgg 960caggatctga gcgagcaagt

acttccggtg ctaaggggac ccgatttgta gaaggcacaa 1020atattaatag atcactttta gctcttggga atgtcatcaa tgccttagca gattcaaaga 1080gaaagaatca gcatatccct tacagaaata gtaagcttac tcgcttgtta aaggattctc 1140ttggaggaaa ctgtcaaact ataatgatag ctgctgttag tccttcctct gtattctacg 1200atgacacata taacactctt aagtatgcta accgggcaaa ggacattaaa tcttctttga 1260agagcaatgt tcttaatgtc aataatcata taactcaata tgtaaagatc tgtaatgagc 1320agaaggcaga gattttattg ttaaaagaaa aactaaaagc ctatgaagaa cagaaagcct 1380tcactaatga aaatgaccaa gcaaagttaa tgatttcaaa ccctcaggaa aaagaaatcg 1440aaaggtttca agaaatcctg aactgcttgt tccagaatcg agaagaaatt agacaagaat 1500atctgaagtt ggaaatgtta cttaaagaaa atgaacttaa atcattctac caacaacagt 1560gccataaaca aatagaaatg atgtgttctg aagacaaagt agaaaaggcc actggaaaac 1620gagatcatag acttgcaatg ttgaaaactc gtcgctccta cctggagaaa aggagggagg 1680aggaattgaa gcaatttgat gagaatacta attggctcca tcgtgtcgaa aaagaaatgg 1740gactcttaag tcaaaacggt catattccaa aggaactcaa gaaagatctt cattgtcacc 1800atttgcacct ccagaacaaa gatttgaaag cacaaattag acatatgatg gatctagctt 1860gtcttcagga acagcaacac aggcagactg aagcagtatt gaatgcttta cttccaaccc 1920taagaaaaca atattgcaca ttaaaagaag ccggcctgtc aaatgctgct tttgaatctg 1980acttcaaaga gatcgaacat ttggtagaga ggaaaaaagt ggtagtttgg gctgaccaaa 2040ctgccgaaca accaaagcaa aacgatctac cagggatttc tgttcttatg acctttccac 2100aacttggacc agttcagcct attccttgtt gctcatcttc aggtggaact aatctggtta 2160agattcctac agaaaaaaga actcggagaa aactaatgcc atctcccttg aaaggacagc 2220atactctaaa gtctccacca tctcaaagtg tgcagctcaa tgattctctt agcaaagaac 2280ttcagcctat tgtatataca ccagaagact gtagaaaagc ttttcaaaat ccgtctacag 2340taaccttaat gaaaccatca tcatttacta caagttttca ggctatcagc tcaaacataa 2400acagtgataa ttgtctgaaa atgttgtgtg aagtagctat ccctcataat agaagaaaag 2460aatgtggaca ggaggacttg gactctacat ttactatatg tgaagacatc aagagctcga 2520agtgtaaatt acccgaacaa gaatcactac caaatgataa caaagacatt ttacaacggc 2580ttgatccttc ttcattctca actaagcatt ctatgcctgt accaagcatg gtgccatcct 2640acatggcaat gactactgct gccaaaagga aacggaaatt aacaagttct acatcaaaca 2700gttcgttaac tgcagacgta aattctggat ttgccaaacg tgttcgacaa gataattcaa 2760gtgagaagca cttacaagaa aacaaaccaa caatggaaca taaaagaaac atctgtaaaa 2820taaatccaag catggttaga aaatttggaa gaaatatttc aaaaggaaat ctaagataaa 2880tcacttcaaa accaagcaaa atgaagttga tcaaatctgc ttttcaaagt ttatcaatac 2940cctttcaaaa atatatttaa aatctttgaa agaagaccca tcttaaagct aagtttaccc 3000aagtactttc agcaagcaga aaaatgaaac tctttgtttt cttcttttgt gttctaaaaa 3060aataaaattt caaaagaaaa ggttgtcttt taagtttttt aaatatttgt tgccttttaa 3120aatccctgag tgtaagttac catggtggca gcttagtttt actatgccac aacaagttga 3180ctaggacatt ttagtaaatg gtagtgagtt aaattatctt tattattttt taaaaataag 3240aatttagaag tggtaaaatt atggcccaag atgtatttgg ttctctatta tgttttgata 3300cattatttta atcatatata tgactttcct tttcaaaaat actttaatgt acaagtgtaa 3360atatatgtgc ccataaaatc attgtaaata ttatttagtc atcacaaata aaatattgtc 3420ccttgctact tgatatatta aagatgtaga ttttaaagtg ttt 3463487533DNAHomo sapiens 48gcgacgctca cgaacgatca gagctgcggg cgacgcaacg aagcccggag gccgcaggct 60gcgcgctccc tcgcagcagc cgggcgggca aaagccccca gtcctcggcc cccgcgcaag 120cgacgccggg aaatgcccac atccgggaaa cctgcagcgg agtgcggcgg cggcgacact 180gagtggaagg caaaatggcg gcggcggcgg cggtggcctg gtgttaaggg gagagccagg 240tcctcacgac ccctgggacg ggccgcgctg gcccgcggca gcccccccgt tcgtctcccc 300gctctgcccc accagggata cttggggttg ctgggacgga ctctggccgc ctcagcgtcc 360gccctcaggc ccgtggccgc tgtccaggag ctctgctctc ccctccagag ttaattattt 420atattgtaaa gaattttaac agtcctgggg acttccttga aggatcattt tcacttttgc 480tcagaagaaa gctctggatc tatcaaataa agaagtcctt cgtgtgggct acatatatag 540atgttttcat gaagaggagt gaaaagccag aaggatatag acaaatgagg cctaagacct 600ttcctgccag taactatact gtcagtagcc ggcaaatgtt acaagaaatt cgggaatccc 660ttaggaattt atctaaacca tctgatgctg ctaaggctga gcataacatg agtaaaatgt 720caaccgaaga tcctcgacaa gtcagaaatc cacccaaatt tgggacgcat cataaagcct 780tgcaggaaat tcgaaactct ctgcttccat ttgcaaatga aacaaattct tctcggagta 840cttcagaagt taatccacaa atgcttcaag acttgcaagc tgctggattt gatgaggata 900tggttataca agctcttcag aaaactaaca acagaagtat agaagcagca attgaattca 960ttagtaaaat gagttaccaa gatcctcgac gagagcagat ggctgcagca gctgccagac 1020ctattaatgc cagcatgaaa ccagggaatg tgcagcaatc agttaaccgc aaacagagct 1080ggaaaggttc taaagaatcc ttagttcctc agaggcatgg cccgccacta ggagaaagtg 1140tggcctatca ttctgagagt cccaactcac agacagatgt aggaagacct ttgtctggat 1200ctggtatatc agcatttgtt caagctcacc ctagcaacgg acagagagtg aaccccccac 1260caccacctca agtaaggagt gttactcctc caccacctcc aagaggccag actccccctc 1320caagaggtac aactccacct cccccttcat gggaaccaaa ctctcaaaca aagcgctatt 1380ctggaaacat ggaatacgta atctcccgaa tctctcctgt cccacctggg gcatggcaag 1440agggctatcc tccaccacct ctcaacactt cccccatgaa tcctcctaat caaggacaga 1500gaggcattag ttctgttcct gttggcagac aaccaatcat catgcagagt tctagcaaat 1560ttaactttcc atcagggaga cctggaatgc agaatggtac tggacaaact gatttcatga 1620tacaccaaaa tgttgtccct gctggcactg tgaatcggca gccaccacct ccatatcctc 1680tgacagcagc taatggacaa agcccttctg ctttacaaac agggggatct gctgctcctt 1740cgtcatatac aaatggaagt attcctcagt ctatgatggt gccaaacaga aatagtcata 1800acatggaact atataacatt agtgtacctg gactgcaaac aaattggcct cagtcatctt 1860ctgctccagc ccagtcatcc ccgagcagtg ggcatgaaat ccctacatgg caacctaaca 1920taccagtgag gtcaaattct tttaataacc cattaggaaa tagagcaagt cactctgcta 1980attctcagcc ttctgctaca acagtcactg caattacacc agctcctatt caacagcctg 2040tgaaaagtat gcgtgtatta aaaccagagc tacagactgc tttagcacct acacaccctt 2100cttggatacc acagccaatt caaactgttc aacccagtcc ttttcctgag ggaaccgctt 2160caaatgtgac tgtgatgcca cctgttgctg aagctccaaa ctatcaagga ccaccaccac 2220cctacccaaa acatctgctg caccaaaacc catctgttcc tccatacgag tcaatcagta 2280agcctagcaa agaggatcag ccaagcttgc ccaaggaaga tgagagtgaa aagagttatg 2340aaaatgttga tagtggggat aaagaaaaga aacagattac aacttcacct attactgtta 2400ggaaaaacaa gaaagatgaa gagcgaaggg aatctcgtat tcaaagttat tctcctcaag 2460catttaaatt ctttatggag caacatgtag aaaatgtact caaatctcat cagcagcgtc 2520tacatcgtaa aaaacaatta gagaatgaaa tgatgcgggt tggattatct caagatgccc 2580aggatcaaat gagaaagatg ctttgccaaa aagaatctaa ttacatccgt cttaaaaggg 2640ctaaaatgga caagtctatg tttgtgaaga taaagacact aggaatagga gcatttggtg 2700aagtctgtct agcaagaaaa gtagatacta aggctttgta tgcaacaaaa actcttcgaa 2760agaaagatgt tcttcttcga aatcaagtcg ctcatgttaa ggctgagaga gatatcctgg 2820ctgaagctga caatgaatgg gtagttcgtc tatattattc attccaagat aaggacaatt 2880tatactttgt aatggactac attcctgggg gtgatatgat gagcctatta attagaatgg 2940gcatctttcc agaaagtctg gcacgattct acatagcaga acttacctgt gcagttgaaa 3000gtgttcataa aatgggtttt attcatagag atattaaacc tgataatatt ttgattgatc 3060gtgatggtca tattaaattg actgactttg gcctctgcac tggcttcaga tggacacacg 3120attctaagta ctatcagagt ggtgaccatc cacggcaaga tagcatggat ttcagtaatg 3180aatgggggga tccctcaagc tgtcgatgtg gagacagact gaagccatta gagcggagag 3240ctgcacgcca gcaccagcga tgtctagcac attctttggt tgggactccc aattatattg 3300cacctgaagt gttgctacga acaggataca cacagttgtg tgattggtgg agtgttggtg 3360ttattctttt tgaaatgttg gtgggacaac ctcctttctt ggcacaaaca ccattagaaa 3420cacaaatgaa ggttatcaac tggcaaacat ctcttcacat tccaccacaa gctaaactca 3480gtcctgaagc ttctgatctt attattaaac tttgccgagg acccgaagat cgcttaggca 3540agaatggtgc tgatgaaata aaagctcatc cattttttaa aacaattgac ttctccagtg 3600acctgagaca gcagtctgct tcatacattc ctaaaatcac acacccaaca gatacatcaa 3660attttgatcc tgttgatcct gataaattat ggagtgatga taacgaggaa gaaaatgtaa 3720atgacactct caatggatgg tataaaaatg gaaagcatcc tgaacatgca ttctatgaat 3780ttaccttccg aaggtttttt gatgacaatg gctacccata taattatccg aagcctattg 3840aatatgaata cattaattca caaggctcag agcagcagtc ggatgaagat gatcaaaaca 3900caggctcaga gattaaaaat cgcgatctag tatatgttta acacactagt aaataaatgt 3960aatgaggatt tgtaaaaggg cctgaaatgc gaggtgtttt gaggttctga gagtaaaatt 4020atgcaaatat gacagagcta tatatgtgtg ctctgtgtac aatattttat tttcctaaat 4080tatgggaaat ccttttaaaa tgttaattta ttccagccgt ttaaatcagt atttagaaaa 4140aaattgttat aaggaaagta aattatgaac tgaatattat agtcagttct tggtacttaa 4200agtacttaaa ataagtagtg ctttgtttaa aaggagaaac ctggtatcta tttgtatata 4260tgctaaataa ttttaaaata caagagtttt tgaaattttt ttgaaagaca gttttagttt 4320tatcttgctt taaccaaata tgaaacatac cccctatttt acagagctct tttttcccct 4380cataaccttg tttttggtag aaaataagct agagaaatta agccatcgtg ttggtgagtg 4440ttcctaggct aatgataatc tgtataattc acatcctgaa actaaggaat acagggttga 4500aaaaatatta atatgtttgt cagaaggaaa aataatgcat ttatcttccc ccccaccccc 4560cgccccatgg aatatttaat ctatttaatc ttcttgcatt tatttctcaa gaattactgg 4620ctttaaaaga agccaaagca ctactagctt tttttccata ttggtatttt tgatgctgct 4680tccaatttta aaagggaaca aagctgccat aaatcgaaat gttcaatact aaaagctaaa 4740atatttctca ccatcctaag cagataatta ttttaatttt catatacttt tcctgtatag 4800taactatttt gattatatca tcaatgttac ctgtttcctc tttcagaaca gtgctgcata 4860tacagattgt tattggcaaa ggaaaatctg gctatctggc aatattttac ctaagcgcag 4920attaattggt gaaaaaatta actcttaaga tggccattaa taattaggaa agtttacaga 4980gtggtcttag tagaaaattc aagtcctcct aatttattta aggttcaata atgcgttcaa 5040catgcctgtt atgtataacg cttaggttct aaggaagatt aaggtttcat accaaaatac 5100atgtagctta tcttttagga aggggaaaaa ggctccattt tgaccatagt aaaatttgtg 5160ttgtgtttta tttccttttc ttaagctcca ctgataaggg attgttttta tcaaaagtta 5220ctatttgtag attggaggca taattttagt gattttcata cttttagctt tcttcgcata 5280aaagctaatt gaaaccgtat atgtagtaaa attaaaggca gagctgttgc agttgaattg 5340gagagttagg gcaaagaaca cttattagcc cacacttccc acctttctac aggtggtcct 5400ttcagagctc agcctgaaaa cccactactg tgttatcgtg cgtcttttgg ggttagtggt 5460tcttttgaga atctgaagga agctgtggac tcttcctaga aaaaaaaacc acacatacac 5520atacaatgtt gcatgcagtt tcaagggatt ttggacatat tgaaacctat cacaggctgt 5580aggttatgga cctctgtgcc atgagaaaat tgatacatta aactaagaac tttgttttta 5640acttaccaat cactactcag cacatcttat ataagctgat aatttgtgat ggaaaaggtc 5700tgtagcatgt gatataaggt gaccttatga atgcctctct tgctggtaca ttaagttgtt 5760ttaatatatc atttggaggg gactgaaatg ttaggctcat tacaagcttg atacagaaat 5820atttctgaag gatttctaat cagaattgta aaacaatgtg ctatcatgaa atcgcagtct 5880tcacctcatg gttcatggaa catttggtta gtcccataaa atcctatgca aaacaaagta 5940gttcaagaat ttttaggtgg gtagtcacat ttataaggta ttcctcttac tctttgggct 6000ttttcagtct gatttattta aattttcatt tagttgtttt acttttggac taaggtgcaa 6060tacagtagaa gataactttg ttacatttat gttgtaggaa aactaaggtg ctgtctcctc 6120ccccttccct tcccacaaaa tctgtattcc ccctattgct gaaatgtaac agacactaca 6180aattttgtat tctttttttg ttttttgttt tgagacaggg tctcactctg tcacccaggc 6240tggagggcag tggcgcttca cagctcactg catcctcaac cttgggggct cacgcagtcc 6300tcccgcctca gcctcccaag tagctgggca tgcgccacca agcccagcta atttttgtat 6360ctttagtaga gatggggttt cgccatgttg cccaggttgg tgtggaattc ctgggctcca 6420gttatatgcc cacctcagcc tcccaaagtg ctgggattac agacgtgacc caccgcgcct 6480ggcgcaaata tgtattcttt taaaatttcc tctgatacta taagcttttt gcatttatct 6540gaagcagtat acatgccttt ggtatcagca attttaacag tttggatata cttatcagct 6600atcttattcc aaaactacat ctacttcttc cagtatagaa tctggtgctt cctgaccaaa 6660aagatgagaa aaacaatgtt aaaaatatag atgctttcca ttgaaatgga gtgaaaacat 6720tggttctata tgttttcttt taaaataatt ttcttattaa aaacttgctg tctttattat 6780acttaccctt tttatgcata tcaatagtat ttataagatg tgttctataa ttatgtaatt 6840gtagatactg ttatgcattg tccagtgaca tcataaggca ggccctactg ctgtatcttt 6900tctaccttct tatttgtaat agaaactata gaatgtatga ctaaaaagtc actttgagat 6960tgactttttt aaaaagttat taccttctgc tgttgcaaag tgcaaaactg tgagtggaat 7020tgttttattc tgacttaatg tgttagaaat tagagaatac agtgggagga tttttagaca 7080ttgctgctgc tgttacccaa ggtattttag ataaaaaatt tttaataaac atccctttgg 7140tatttaaagt ggaacattta gcctgttcat tttaatctaa agcaaaaagt aatttgggtc 7200aaaatattgg tatatttgta aagcgcctta atatatccct ttgtggaagg cactacacag 7260tttactttta tattgtattg tgtatataag tattttgtat taaaattgaa tcagtggcaa 7320cattaaagtt ttataaaatc atgctttgtt agaaaaagaa ttacagcttt gcaatataac 7380taattgtttc gcataattct gaatgtaata gatatgaata atcagcctgt gtttttaatg 7440aacttatttg tattttccca atcattttct ctagtgtaat gtttgctggg ataataaaaa 7500aaattcaaat ctttcaaaaa aaaaaaaaaa aaa 7533493701DNAHomo sapiens 49taggcggtgc atcccgttcg cgcctggggc tgtggtcttc ccgcgcctga ggcggcggcg 60gcaggagctg aggggagttg tagggaactg aggggagctg ctgtgtcccc cgcctcctcc 120tccccatttc cgcgctcccg ggaccatgtc cgcgctggcg ggtgaagatg tctggaggtg 180tccaggctgt ggggaccaca ttgctccaag ccagatatgg tacaggactg tcaacgaaac 240ctggcacggc tcttgcttcc ggtgttcaga atgccaggat tccctcacca actggtacta 300tgagaaggat gggaagctct actgccccaa ggactactgg gggaagtttg gggagttctg 360tcatgggtgc tccctgctga tgacagggcc ttttatggtg gctggggagt tcaagtacca 420cccagagtgc tttgcctgta tgagctgcaa ggtgatcatt gaggatgggg atgcatatgc 480actggtgcag catgccaccc tctactgtgg gaagtgccac aatgaggtgg tgctggcacc 540catgtttgag agactctcca cagagtctgt tcaggagcag ctgccctact ctgtcacgct 600catctccatg ccggccacca ctgaaggcag gcggggcttc tccgtgtccg tggagagtgc 660ctgctccaac tacgccacca ctgtgcaagt gaaagaggtc aaccggatgc acatcagtcc 720caacaatcga aacgccatcc accctgggga ccgcatcctg gagatcaatg ggacccccgt 780ccgcacactt cgagtggagg aggtggagga tgcaattagc cagacgagcc agacacttca 840gctgttgatt gaacatgacc ccgtctccca acgcctggac cagctgcggc tggaggcccg 900gctcgctcct cacatgcaga atgccggaca cccccacgcc ctcagcaccc tggacaccaa 960ggagaatctg gaggggacac tgaggagacg ttccctaagg cgcagtaaca gtatctccaa 1020gtcccctggc cccagctccc caaaggagcc cctgctgttc agccgtgaca tcagccgctc 1080agaatccctt cgttgttcca gcagctattc acagcagatc ttccggccct gtgacctaat 1140ccatggggag gtcctgggga agggcttctt tgggcaggct atcaaggtga cacacaaagc 1200cacgggcaaa gtgatggtca tgaaagagtt aattcgatgt gatgaggaga cccagaaaac 1260ttttctgact gaggtgaaag tgatgcgcag cctggaccac cccaatgtgc tcaagttcat 1320tggtgtgctg tacaaggata agaagctgaa cctcctgaca gagtacattg aggggggcac 1380actgaaggac tttctgcgca gtatggatcc gttcccctgg cagcagaagg tcaggtttgc 1440caaaggaatc gcctccggaa tggcctattt gcactctatg tgcatcatcc accgggatct 1500gaactcgcac aactgcctca tcaagttgga caagactgtg gtggtggcag actttgggct 1560gtcacggctc atagtggaag agaggaaaag ggcccccatg gagaaggcca ccaccaagaa 1620acgcaccttg cgcaagaacg accgcaagaa gcgctacacg gtggtgggaa acccctactg 1680gatggcccct gagatgctga acggaaagag ctatgatgag acggtggata tcttctcctt 1740tgggatcgtt ctctgtgaga tcattgggca ggtgtatgca gatcctgact gccttccccg 1800aacactggac tttggcctca acgtgaagct tttctgggag aagtttgttc ccacagattg 1860tcccccggcc ttcttcccgc tggccgccat ctgctgcaga ctggagcctg agagcagacc 1920agcattctcg aaattggagg actcctttga ggccctctcc ctgtacctgg gggagctggg 1980catcccgctg cctgcagagc tggaggagtt ggaccacact gtgagcatgc agtacggcct 2040gacccgggac tcacctccct agccctggcc cagccccctg caggggggtg ttctacagcc 2100agcattgccc ctctgtgccc cattcctgct gtgagcaggg ccgtccgggc ttcctgtgga 2160ttggcggaat gtttagaagc agaacaagcc attcctatta cctccccagg aggcaagtgg 2220gcgcagcacc agggaaatgt atctccacag gttctggggc ctagttactg tctgtaaatc 2280caatacttgc ctgaaagctg tgaagaagaa aaaaacccct ggcctttggg ccaggaggaa 2340tctgttactc gaatccaccc aggaactccc tggcagtgga ttgtgggagg ctcttgctta 2400cactaatcag cgtgacctgg acctgctggg caggatccca gggtgaacct gcctgtgaac 2460tctgaagtca ctagtccagc tgggtgcagg aggacttcaa gtgtgtggac gaaagaaaga 2520ctgatggctc aaagggtgtg aaaaagtcag tgatgctccc cctttctact ccagatcctg 2580tccttcctgg agcaaggttg agggagtagg ttttgaagag tcccttaata tgtggtggaa 2640caggccagga gttagagaaa gggctggctt ctgtttacct gctcactggc tctagccagc 2700ccagggacca catcaatgtg agaggaagcc tccacctcat gttttcaaac ttaatactgg 2760agactggctg agaacttacg gacaacatcc tttctgtctg aaacaaacag tcacaagcaa 2820aggaagaggc tgggggacta gaaagaggcc ctgccctcta gaaagctcag atcttggctt 2880ctgttactca tactcgggtg ggctccttag tcagatgcct aaaacatttt gcctaaagct 2940cgatgggttc tggaggacag tgtggcttgt cacaggccta gagtctgagg gaggggagtg 3000ggagtctcag caatctcttg gtcttggctt catggcaacc actgctcacc cttcaacatg 3060cctggtttag gcagcagctt gggctgggaa gaggtggtgg cagagtctca aagctgagat 3120gctgagagag atagctccct gagctgggcc atctgacttc tacctcccat gtttgctctc 3180ccaactcatt agctcctggg cagcatcctc ctgagccaca tgtgcaggta ctggaaaacc 3240tccatcttgg ctcccagagc tctaggaact cttcatcaca actagatttg cctcttctaa 3300gtgtctatga gcttgcacca tatttaataa attgggaatg ggtttggggt attaatgcaa 3360tgtgtggtgg ttgtattgga gcagggggaa ttgataaagg agagtggttg ctgttaatat 3420tatcttatct attgggtggt atgtgaaata ttgtacatag acctgatgag ttgtgggacc 3480agatgtcatc tctggtcaga gtttacttgc tatatagact gtacttatgt gtgaagtttg 3540caagcttgct ttagggctga gccctggact cccagcagca gcacagttca gcattgtgtg 3600gctggttgtt tcctggctgt ccccagcaag tgtaggagtg gtgggcctga actgggccat 3660tgatcagact aaataaatta agcagttaac ataactggca a 3701502191DNAHomo sapiens 50atgaagcccc tctacagtgg ctgctgcagg tgctggctgg accccgctgg gccccttctc 60accccacatc ccattgattg attagtcagg cagggcagtg aggacacctc acagatgggg 120aaactgaagc ccagggaggt actcaagatg tgcccagtgc gggctgagat aaggccctgg 180agtccacctc caggctgggt ctgtcctgct ctgctccctg cagggctggt gggcctcctt 240cccccttttg actaacggcc tggcttggag agagggggct cccggcatgg gtgatggcag 300aggctggcac ccttgtggcc agggcctgat ggctcatggg agtgcagggg acattgatgt 360caagggatag ccagacgcct caccttctct ccattctatg ggagtgcagg ggacattgat 420gtcaagggat agccagacgc ctcaccttct ctccattcta ggaaaatcca agaggaagaa 480ggatctacgg atatcctgca tgtccaagcc acccgcaccc aaccccacac ccccccggaa 540cctggactcc cggaccttca tcaccattgg agacagaaac tttgaggtgg aggctgatga 600cttggtgacc atctcagaac tgggccgtgg agcctatggg gtggtagaga aggtgcggca 660cgcccagagc ggcaccatca tggccgtgaa gcggatccgg gccaccgtga actcacagga 720gcagaagcgg ctgctcatgg acctggacat caacatgcgc acggtcgact gtttctacac 780tgtcaccttc tacggggcac tattcagaga gggagacgtg tggatctgca tggagctcat 840ggacacatcc ttggacaagt tctaccggaa ggtgctggat aaaaacatga caattccaga 900ggacatcctt ggggagattg ctgtgtctat cgtgcgggcc ctggagcatc tgcacagcaa 960gctgtcggtg atccacagag atgtgaagcc ctccaatgtc cttatcaaca aggagggcca 1020tgtgaagatg tgtgactttg gcatcagtgg ctacttggtg gactctgtgg ccaagacgat 1080ggatgccggc tgcaagccct acatggcccc tgagaggatc aacccagagc tgaaccagaa 1140gggctacaat gtcaagtccg acgtctggag cctgggcatc accatgattg agatggccat 1200cctgcggttc ccttacgagt

cctgggggac cccgttccag cagctgaagc aggtggtgga 1260ggagccgtcc ccccagctcc cagccgaccg tttctccccc gagtttgtgg acttcactgc 1320tcagtgcctg aggaagaacc ccgcagagcg tatgagctac ctggagctga tggagcaccc 1380cttcttcacc ttgcacaaaa ccaagaagac ggacattgct gccttcgtga aggagatcct 1440gggagaagac tcataggggc tgggcctcgg accccactcc ggccctccag agccccacag 1500ccccatctgc gggggcagtg ctcacccaca ccataagcta ctgccatcct ggcccagggc 1560atctgggagg aaccgagggg gctgctccca cctggctctg tggcgagcca tttgtcccaa 1620gtgccaaaga agcagaccat tggggctccc agccaggccc ttgtcggccc caccagtgcc 1680tctccctgct gctcctagga cccgtctcca gctgctgaga tcctggactg agggggcctg 1740gatgccccct gtggatgctg ctgcccctgc acagcaggct gccagtgcct gggtggatgg 1800gccaccgcct tgcccagcct ggatgccatc caagttgtat atttttttaa tctctcgact 1860gaatggactt tgcacacttt ggcccagggt ggccacacct ctatcccggc tttggtgcgg 1920ggtacacaag aggggatgag ttgtgtgaat accccaagac tcccatgagg gagatgccat 1980gagccgccca aggccttccc ctggcactgg caaacagggc ctctgcggag cacactggct 2040cacccagtcc tgcccgccac cgttatcggt gtcattcacc tttcgtgttt tttttaattt 2100atcctctgtt gattttttct tttgctttat gggtttggct tgtttttctt gcatggtttg 2160gagctgatcg cttctccccc accccctagg g 2191513386DNAHomo sapiens 51gcggtgtttg tctgccggac tgacgggcgg ccgggcggtg cgcggcggcg gtggcggcgg 60ggaagatggc ggcgtcctcc ctggaacaga agctgtcccg cctggaagca aagctgaagc 120aggagaaccg ggaggcccgg cggaggatcg acctcaacct ggatatcagc ccccagcggc 180ccaggcccac cctgcagctc ccgctggcca acgatggggg cagccgctcg ccatcctcag 240agagctcccc gcagcacccc acgccccccg cccggccccg ccacatgctg gggctcccgt 300caaccctgtt cacaccccgc agcatggaga gcattgagat tgaccagaag ctgcaggaga 360tcatgaagca gacgggctac ctgaccatcg ggggccagcg ctaccaggca gaaatcaacg 420acctggagaa cttgggcgag atgggcagcg gcacctgcgg ccaggtgtgg aagatgcgct 480tccggaagac cggccacgtc attgccgtta agcaaatgcg gcgctccggg aacaaggagg 540agaacaagcg catcctcatg gacctggatg tggtgctgaa gagccacgac tgcccctaca 600tcgtgcagtg ctttgggacg ttcatcacca acacggacgt cttcatcgcc atggagctca 660tgggcacctg cgctgagaag ctcaagaagc ggatgcaggg ccccatcccc gagcgcattc 720tgggcaagat gacagtggcg attgtgaagg cgctgtacta cctgaaggag aagcacggtg 780tcatccaccg cgacgtcaag ccctccaaca tcctgctgga cgagcggggc cagatcaagc 840tctgcgactt cggcatcagc ggccgcctgg tggactccaa agccaagacg cggagcgccg 900gctgtgccgc ctacatggca cccgagcgca ttgacccccc agaccccacc aagccggact 960atgacatccg ggccgacgta tggagcctgg gcatctcgtt ggtggagctg gcaacaggac 1020agtttcccta caagaactgc aagacggact ttgaggtcct caccaaagtc ctacaggaag 1080agcccccgct tctgcccgga cacatgggct tctcggggga cttccagtcc ttcgtcaaag 1140actgccttac taaagatcac aggaagagac caaagtataa taagctactt gaacacagct 1200tcatcaagcg ctacgagacg ctggaggtgg acgtggcgtc ctggttcaag gatgtcatgg 1260cgaagactga gtcaccgcgg actagcggcg tcctgagcca gccccacctg cccttcttca 1320ggtagctgct tggcggcggc cagccccaca gggggccagg ggcatggcca caggcccccc 1380tccccacttg gccacccagc tgcctgccag gggagacctg ggacctggac ggccacctag 1440gactgaggac agagagtggg gggtgcccac ccaccccccc cgccccgggc ctaccaagcc 1500cccgcccttc ccaccccggg gtcagccggc cgtgtgcgtc ccccgacaga cactgtgaac 1560ggaagacagc aggccgcgat cagagtcgct gttcattcag ccgcagcctc tgggccgggg 1620cggcccccag gggccaggag agagccctgg agtcccgcag ccaccatgca cgctcccagc 1680gtgctgtgtc cttcgccact cccacgcgcc cgttcctctt ccgtcgccct ctgtcccctg 1740ctctacctct ctgtccttgt ctggctctcc cgtcaccctc cctgcctctg tctctcttct 1800ggcctgagcc tgggcccagc cacctcctga cgggtcccct gggtctgcat aggtctccca 1860tggcgcaatg agtcagtggc ccccagccag gcagtgtggg cattgccact gcggctggac 1920ggggctgcgc gctcgcgctc tctctctctc tctctctctc tctttgatct cagggggtcc 1980tttttggagt ttattgtatt ttattgtact tggtggggtg tttggggtgg gggcggagga 2040gagcttgttc tcgtggggtt gtcggtacct tcagaaactt ttaccaaagt cacgattagc 2100tgcttgtggt ggggccccaa ccgccctcgg gcactgggga gctgggctgg ggctgctgct 2160ctggggtctc cgggggccac agcttggggt gagttgaaga cctcagggga tgtggagggg 2220tctgcggggc cctggccgca caggatggcc ttcagggaag gtggtcttgg ggcatggtgc 2280agagcaggtg accggaggga atcggtgacg gagcggggcc aagggagggg tccggaggga 2340gtcagggatg gagggcagag ggagtggatg tgggggtttg aggacgtgtg acaagctcca 2400gcaggggtgg gggccgggct gagggtgggg gtgcgaggtg gtcactccca tcgtgcccct 2460ggccgtccct ccactcaccc acacctggcc cagtccacgt tgaggtccag gactgggaag 2520gaccgggtga gtgcaccggg gacccaggcc aggtgccccc cggagcctgc tggggtggcc 2580agagcaggag ggggtgtgtt tcctttttgt gggtgttgca tgcaaatcaa gtggacaaga 2640aaaaataaca aaacaaaaaa caagaaaaaa aaaacacaaa accccgtaaa atcacaaaga 2700aaatccaaca ccaaaggcgc agaagccggc tggccgtggt gggggcagcg taggcgtagc 2760atccctctcc tctcacttag cctgttgact cttgttatta tcatgatatt cacaaaacgc 2820cgcatgttta aaaagtcata gatgtcatct tctctctgcc cccagggagg aaagccacct 2880tctcttgccc cttggcccct ttgtcagggg ccaggggtct gccgggtggg ggtgccaaca 2940ggcctggccc tttcctcccc tgcatccagc catgggggcc tctgcgattg ccggaaggtt 3000gcatggctgg tcccagggcc agcacaggcc cgaggccggg ctgcctggtt ttatttttat 3060ttaactttat tttctgtttt atgagtgtgt gtccgcccac ccccaccccc ttcagtgtta 3120agtggggagc cctgggggag tctctcctgc ctcccagcct ctcccaagac ctcccccctc 3180gtcaccagcc atccctctgg accaggcaga gggcggaccg ggtgggcagg ggcctgaggg 3240tggctcgggc cagcccacca gccaatggac ccctcctcag gccgccagtg tcgccctgcc 3300cctttttaaa acaaaatgcc ctcgtttgta aacccttaga cgcttgagaa taaacccctt 3360ccttttcttc caaaaaaaaa aaaaaa 3386529945DNAHomo sapiens 52accagattcc ttctaaaaga aggaaggcca tgtctgcctg aagcctattg gctgggccta 60ctctggaccc gcccctcttt tttttttcat gacacacacc acagcgaagt ctgtgcggaa 120tcctaaacca gcccaattta catccattca tgaatctgtg acgtcagcaa gcctttgggc 180tcctttgcgg tgggctggag gattgtgtgg gtggaatccc cctccccttt atttttccaa 240ttctgcaagg cttttaaaat tcaccttaca tcttttcaaa gcaagaaaat ggaacagcat 300gtgtaggaat tcttcgttgt tgttttggag ccctctctta agtcagaact ctgtcccaaa 360aatcttctga gtgtcatctc aggactttgg ttatactcat ggcacgatgg ccaactttca 420ggagcacctg agctgctcct cttctccaca cttacccttc agtgaaagca aaaccttcaa 480tggactacaa gatgagctca cagctatggg gaaccaccct tctcccaagc tgctcgagga 540ccagcaggaa aaggggatgg tacgaacaga gctaatcgag agcgtgcaca gccccgtcac 600cacaacagtg ttgacgagcg taagtgagga ttccagggac cagtttgaga acagcgttct 660tcagctaagg gaacacgatg aatcagagac ggcggtgtct caggggaaca gcaacacggt 720ggacggagag agcacaagcg gaactgaaga cataaagatt cagttcagca ggtcaggcag 780tggcagtggt gggtttcttg aaggactatt tggatgctta aggcctgtat ggaatatcat 840tgggaaggca tattccactg attacaaatt gcagcagcaa gatacttggg aagtgccatt 900tgaggagatc tcagagctgc agtggctggg tagtggagcc caaggagcgg tcttcttggg 960caagttccgg gcggaagagg tggccatcaa gaaagtgaga gaacagaatg agacggatat 1020caagcatttg aggaagttga agcaccctaa catcatcgca ttcaagggtg tttgtactca 1080ggccccatgt tattgtatta tcatggaata ctgtgcccat ggacaactct acgaggtctt 1140acgagctggc aggaagatca cacctcgatt gctagtagac tggtccacag gaattgcaag 1200tggaatgaat tatttgcacc tccataaaat tattcatcgt gatctcaaat cacctaatgt 1260tttagtgacc cacacagatg cggtaaaaat ttcagatttt ggtacatcta aggaactcag 1320tgacaaaagt accaagatgt catttgctgg cacggtcgca tggatggcgc cagaggtgat 1380acggaatgaa cctgtctctg aaaaagttga tatatggtct tttggagtgg tgctttggga 1440gctgctgaca ggagagatcc cttacaaaga tgtagattct tcagccatta tctggggtgt 1500tggaagcaac agcctccacc ttccagttcc ttccacttgc cctgatggat tcaaaatcct 1560tatgaaacag acgtggcaga gtaaacctcg aaaccgacct tcttttcggc agacactcat 1620gcatttagac attgcctctg cagatgtact tgccacccca caagaaactt acttcaagtc 1680tcaggctgaa tggagagaag aagtgaaaaa acattttgag aagatcaaaa gtgaaggaac 1740ttgtatacac cggttagatg aagaactgat tcgaaggcgc agagaagagc tcaggcatgc 1800gctggatatt cgtgaacact atgagcggaa gcttgagcgg gcgaataatt tatacatgga 1860attgagtgcc atcatgctgc agctagaaat gcgggagaag gagctcatta agcgtgagca 1920agcagtggaa aagaagtatc ctgggaccta caaacgacac cctgttcgtc ctatcatcca 1980tcccaatgcc atggagaaac tcatgaaaag gaaaggagtg cctcacaaat ctgggatgca 2040gaccaaacgg ccagacttgt tgagatcaga agggatcccc accacagaag tggctcccac 2100tgcatcccct ttgtccggaa gtcccaaaat gtccacttct agcagcaaga gccgatatcg 2160aagcaaacca cgccaccgcc gagggaatag cagaggcagc catagtgact ttgccgcaat 2220cttgaaaaac cagccagccc aggaaaattc accccatccc acttacctgc accaagctca 2280atcccaatac ccttctcttc atcaccataa ttctctgcag cagcaatacc agcagccccc 2340tcctgccatg tcccagagtc accatcccag actcaatatg cacggacagg acatagcaac 2400ctgcgccaac aacctgaggt atttcggccc agcagcagcc ctgcggagcc cactcagcaa 2460ccatgctcag agacagctgc ccggctcgag ccctgacctc atctccacag ccatggctgc 2520agactgctgg agaagttctg agcctgacaa gggccaagct ggtccctggg gctgttgcca 2580ggctgacgct tatgacccct gccttcagtg caggccagaa cagtatgggt ccttagacat 2640accctctgct gagccagtgg ggaggagccc tgacctttcc aagtcaccag cacataatcc 2700tctcttggaa aacgcccaga gttctgagaa aacggaagaa aatgaattca gcggctgtag 2760gtctgagtca tccctcggca cctctcatct cggcacccct ccagcgctac ctcgaaaaac 2820aaggcctctg cagaagagtg gagatgactc ctcagaagag gaagaagggg aagtagatag 2880tgaagttgaa tttccacgaa gacagaggcc ccatcgctgt atcagcagct gccagtcata 2940ttcaaccttt agctctgaga atttctctgt gtctgatgga gaagagggaa ataccagtga 3000ccactcaaac agtcctgatg agttagctga taaacttgaa gaccgcttgg cagagaagct 3060agacgacctg ctgtcccaga cgccagagat tcccattgac atatcctcac actcggatgg 3120gctctctgac aaggagtgtg ccgtgcgccg tgtgaagact cagatgtctc tgggcaagct 3180gtgtgtggag gaacgtggct atgagaaccc catgcagttt gaagaatcgg actgtgactc 3240ttcagatggg gagtgttctg atgccacagt taggaccaat aaacactaca gctctgctac 3300ctggtaatga aggaatacac atcctgaaga tctcgtgact atactggcat ttcagatcca 3360ccccaccccc agactcatcc cactctctcc cagcattttg tctgggaaga gagactaccc 3420catctttacc accccctaga aatgagctgc aataacagga acatgagact tcgcaaatct 3480ctggaaaata atatccaaat gaaattaagt ctcactgaac atttcaatca agaatggcag 3540ggatctattt tattgaatat tctagctact gtaacattga tatttatttt tgtttgacat 3600tttaacactt tgtactgcaa agagtgaact atatatgaga tagagagaca ataatttctt 3660gcaaaaaaaa aaagagataa aagaaagaac agaaaaaaag aaataagtgg aatttaagag 3720caacatcctt gggaatttgt ggggccggga ggtattattg ctgcttgaac aggggaccag 3780gtcttttggc cataagtgac taaagaagag ccagagcaag acattgaaca ttttagaaca 3840caaagaacag caaaagaaaa gcaattccag gcaacttgtg aacagaccat attcacttca 3900accagcttgt ccaggtggct tacggaaatg acctagaaaa gtctggtgac cagatacttg 3960cacccaatgt cttcaagggc atgtgcttcc tctaggaggg aaaaacagac aaacaaacaa 4020acaaacaaac ctgtgtatgt ggaagctggt ttcattttta aatgtttaag cagcagttgg 4080tagtgaggtt tacagatagt gtcaaatctt gtttttggca aatacgtccc tttttagtgc 4140tgtcactgtc attaccttgg caaatgtgct accttgaccc aacgtgttga tctttcatac 4200tcaagtgcca tttccttgta gctcatttcc tttctgcctg ctgaccactt cctgtaggaa 4260caaaggttgg ggggcagtac tgaggaggag aaaagggtga gagaggaaga acatctacag 4320tggtgttagg aaaacgaacg tggaatttat aaaactccat tctcaggatc actcagttca 4380gctacgagga gaagatggaa ccacccctct ctggagccag gttgcttgtc tacttgagtc 4440atattgattc aagcaggaga acagactttg aaggcagcta ggatgtatgt gtgtctatac 4500aatgtctgag cccaaaccat ccctttgttt ttattcaata actcattcta tcttagaagt 4560tctttttttt tttttttttt ttgacagagt tttgctcttt ttgcccaggc tagagtgcaa 4620tggcacaatc tcagttcact gcaacctcca tctcccaggt tcaagcgatt ctcctgcctc 4680agcctcccga gtagctggga ttacaggcgc ccgcaaccac gcctggctaa ttttgtattt 4740ttagtagaca cggggtttca ccatgttggc caggcttgtc tcaaactcct gacctcaggt 4800gatccgcctg cctcggcctc ccaaagtgct gggattacag gcatcagcca ctgtgcccgg 4860cctatcttag aagtcttaat gactggctac cactgtcaga ataaaagcaa aaacaagcag 4920cttgcaaaag gcaactcctc tcccagcaca atagcatttt tgttcaatgc tacttgtaaa 4980atatctttta cttcactcca aatcaatgca gttttaaata actggatttg aacatttgtg 5040gaaagaacaa gggatgctga gcagggatag gaaggatttt tacattgcca aaagcatgag 5100gtcctgcctg tctccagggt catgggctct gaaaagcatt ccaaggtact tcatggtgcc 5160ttggccttaa ggaaaaattt ttttagaatt ttatgtacaa ataggtgttg acctagtacc 5220tgtccctgtc tccaagacag attaccgtca aacaacctct ctagattcac tggactcttt 5280gacactgcat catgttggac gttaggaaat acttgcacag acagctgtta aaccatttcc 5340aatgcacatg aaaatgttgc cgctcctctg ggttttactg attgcatcag ccaaaaagga 5400aaggcaggag ggaatttaga gttccttttg cttgtttgat ccatttgttt acactttatg 5460ttgatacatt gatttaaaat gtagtgtctg tgatttatag ctcttaggat gaaggaaaat 5520gtttaattta tacaaagagc agtattgttt gcattaattt attccatttt gtaaaaattc 5580tgtagctgga ctacatgaaa gatcttaagt tatggcatta ttatcattgt tattttattt 5640tataatatta tcattctcat tttctgtcga tcagaaggtg tgatttatga tgtggcacaa 5700tggttgtgtt tattgctaac caggaattat tatggatttt atgattttaa tgaaggaatg 5760aaaatggaat tcccatttgg gagctccctg gtattgatct tagctgtgtt ccctaatttt 5820ctgtgtacaa caatcatctg aggacgcatg ttctgccctg aagcccaatg gatacattgt 5880gattttgact tgatcatgaa agctcctggg tgggccgatg acccccagga tgtcaaatag 5940tggatggaca tatagttaaa aagctgtaaa ctttctaaag tttcttagga aataaattca 6000tgggactata ttagaaataa aaagagaatg atttaatgtc ctgagaggaa cagacctaga 6060gggtttccgc acagggctca tggattcgtt tcaagaattg acaacatagt ttgcaatctc 6120cttcctgcca gacccctttg ttctcccacc tttattctcc tagtggagag tagcagggag 6180actaaaaaaa gaaatggtat acagtagtcc cctcttaccc atggcttcat tttcatggtt 6240tcagttacgc tcaacagcag tccaaaaata tttgatggaa cattccagaa ataaacaatt 6300cataaatttt aattgcacag cattctgagg agcatgatga gatcttgccc cttgctgccc 6360tggaggtgat cctccctctg tccagcatat tcatgctgct catccattag tcacttagta 6420gcagtctcgg tgatcagatc gactgtctcg gttatcagat gactgtatcg cagtgcttgt 6480gttcaagtac ccctatttaa ttaataatag ccccaaaggg caagagtgct gtgcctaatt 6540tacaaattaa attttatcat agatatgtaa gtatagaaaa aaaaacatag tatatatagg 6600gtttggtact atcagagttt ttaggcatcc actgggggtc ttggaatgta tcccccagaa 6660ataagggagg actaccgtat atacatgtag ggcatgacat aaaatgccta actgtgatgt 6720catcctagaa caagactaaa gaactttaag aaggaggcct ggtcacttag aggaccaacg 6780actggaaaaa aattcttgaa aggctatatt ttccatcctc ttgacttcag atctcactgt 6840actgtaaatc tctctggttc attattcctt ggaacagaga tgctacaact ctatgtcttc 6900tttctatcca acataaaaca ctggcagttt tgtccaattc ttgcccacct ttagtggcaa 6960cagagaaaca tgagggtcag cttttatctt acatctttca gtgatggtct tcctagaaaa 7020cctacccctg atacctcgta attttgatca gttttttttg aattctcatc ttgattatct 7080gttatgctat tgtcatcata caccttatgt ggattaactg ttatgagtat gttagggtag 7140tacgtagtgg ctgaatctca gtcattcatt gtatagtcga gagttgaata aagtccatat 7200tgaacacatt tttttaagta gaattgacta gaggtttcag aggagaataa ggtccttagt 7260ggaggttaaa aagggaaata ccttctctag cccagcctgg tccttcgctg cctgccttgt 7320gataaccggg aaaatcttga attgatgtat gtttctttga gaacgactcc acagtcatct 7380gaagagtgtt gaatcaagag ctcagggaag ttatgagcta attcttcagt cctgacaagt 7440gtgttacaac agtgcttcca ggaacctcac aagactgtga tttcaagctg cttcattgat 7500ggaaagtttc accatcttgg gatgaatgtc catgttccgt tagcgtctgt ttttaactga 7560ctgcaagatg atgagtttta atttgggttg cagatgagca tttggttctg attttcatct 7620atttcaagat catatcctct ggataacagt tccttttaaa attgctttgc agaggggctg 7680agaagcctgc atctactttg aaattataat ggaccttacc accacttaag tttagacctg 7740tttgcaagat ggtggggagc tcctactgag aaagatgaag atgctagctc tattgtaaac 7800tggcgtcttc atctagctac ttgaagttga gatactatat tttaaaatgt tggcatcaaa 7860caaatctatc cttctagaag taaagacatt ttgagtagga tttagtaagt actggacatc 7920tcctgtagag cttcatcatg ctaaattatt cccctctcct tttctaaata atagatgtgc 7980ttgggtttgg gatttacctg gcaccaaccc agactttttt tggggggggg tgagggcgca 8040ggatctcact ctgtcaccag gttggagtac agtggcatga ttatggctca ctgcagcctc 8100aacctcctgg gctcaagtga tcctcccacc tcagcctcct gagtagctgg gaccacaggt 8160gtgtgccacc atgcacaaca attttttttt tttttttgta gagatgggcg tctccctgtg 8220ttgcccaggc tggtatcgaa ctctgggctc tagcgatcct cctgctttgg cctcccaaag 8280tactgggatt acaaacgtga gctgccatgc ccagcctcca gactatttta aatgccctct 8340cccactgtgg aacattggca tcctttaaga ataaatgcat cctttttgat caaatgattt 8400actctttttt tcttcaatgt cctcatgtct caattttttt ttccttttct taaaacagtc 8460ccacttgaac ttcctggaac tgaattctcc agaacataat atttataatc catagaattc 8520ctgccctgct ctgcagtaga gtgtgctatg ttttgttttc ccactgagcc agaagccgaa 8580atattatact accacttacc accatctacc acctccaaga ccaagaccaa cattatgtat 8640tgagcatcgt atctttccta ctgagcctag acacagcctc agaacctctc aacatagcac 8700ttggagcaac aattgccgct tgattggaat tgccatttga gcttgagtta gccccaatgg 8760cagaacgaca ggctcgcact agtgtccacc tgtggctgtc aggggcggta ccacagaaag 8820gggaaaggcc acttgcctct acccactgcc cttttggaca acaattccaa ttgaaggaac 8880accaatcact gatggatccc attccaaaat gtctcttcat tcacatcatt taattctgtt 8940gaatgaatat gttcctccct caccttttat aaacagaaaa ttaatataag tcccagttac 9000ttgcttctta gactctgtga gactcatgta ccaaaacaat gtgacattct tttcgagact 9060ttgacttgta cggtcagtat gaatttagtg cctttccagg cagcaaaatg tttcttcttt 9120gctgatttca taggacaaat atcctagcat actcacacca ccagtgtccc accctcacag 9180actggcacat tagaatcata ttaatctgct tgtttgcatg ttacaactga tactgcaaaa 9240gcctattcaa gtcggactga actaggctaa gcagaggacc cttgtggaac ctggagcatt 9300tctcagggac aggtggctaa agaggggagc tctaaaatca ctgctctgag aaacaggagg 9360tgggttaagg cttttgttaa ctgtcatgtg gccagggtac gatggcagga cttcacagag 9420cagagcccta agcagatggc aaggccactg taaggaagct cccggcagca tcccaggtct 9480gctctccaga gccacttcac agcactcagg gatcgctggc tcccggccct aggctgctgt 9540ccagtgacca ggtggacagg gtcctccagt gactgcaggc caagggaacc ccagccagca 9600tgtgcaagct attaggaaga tgtcccatct tgcccatatc accccagtgg ctcttcacct 9660tcagagtgac cacttcccag actctggaag tgggaagacc ctctttgacg ctttattaca 9720gtaatttgag ctcctatcga cttggagcga atgaatttct cttttgtggt taggtctcca 9780aatgaacctc cttacctggc tcccctctgg tctcctgtac tgtcagtccc cagctcccag 9840tgttgttttc tgatgccggc tccctctctg tattgaacgg caatgggaac aagaatgact 9900atcaaagcaa acaaatgcat ggaattaaac aaaaagtgta cttca 9945532163DNAHomo sapiens 53gggccggcgg cggcggcggc gcgcggagga gaccgcagtg cggccggcgc taggacccgc 60gggggcctcc caggccgcgg cgcctcccgc tttcccccac tccccgaccc ttcttcgccc 120ccaaaatgag gaaacggagc aactcgctcc aagttgtgca gccgggaccg cctcggggtg 180tgcagccggc tcgcggaggc cctcctgggg gcgggcgcgg ggcgcggctc gggggcgccc 240cctgagcaga aaacaggaag aaccaggctc ggtccagtgg cacccagctc cctacctcct 300gtgccagccg actggcctgt ggcaggccat tcccagcgtc cccgactgtg accacttgct 360cagtgtgcct ctcacctgcc tcagtttccc tctgggggcg atggcggggc gaggctctct 420ggtttcctgg cgggcatttc acggctgtga ttctgctgag gaacttcccc gggtgagccc 480ccgcttcctc cgagcctggc acccccctcc cgtctcagcc aggatgccaa cgaggcgctg 540ggccccgggc acccagtgta tcaccaaatg cgagcacacc cgccccaagc caggggagct 600ggccttccgc aagggcgacg

tggtcaccat cctggaggcc tgcgagaaca agagctggta 660ccgcgtcaag caccacacca gtggacagga ggggctgctg gcagctgggg cgctgcggga 720gcgggaggcc ctctccgcag accccaagct cagcctcatg ccgtggttcc acgggaagat 780ctcgggccag gaggctgtcc agcagctgca gcctcccgag gatgggctgt tcctggtgcg 840ggagtccgcg cgccaccccg gcgactacgt cctgtgcgtg agctttggcc gcgacgtcat 900ccactaccgc gtgctgcacc gcgacggcca cctcacaatc gatgaggccg tgttcttctg 960caacctcatg gacatggtgg agcattacag caaggacaag ggcgctatct gcaccaagct 1020ggtgagacca aagcggaaac acgggaccaa gtcggccgag gaggagctgg ccagggcggg 1080ctggttactg aacctgcagc atttgacatt gggagcacag atcggagagg gagagtttgg 1140agctgtcctg cagggtgagt acctggggca aaaggtggcc gtgaagaata tcaagtgtga 1200tgtgacagcc caggccttcc tggacgagac ggccgtcatg acgaagatgc aacacgagaa 1260cctggtgcgt ctcctgggcg tgatcctgca ccaggggctg tacattgtca tggagcacgt 1320gagcaagggc aacctggtga actttctgcg gacccggggt cgagccctcg tgaacaccgc 1380tcagctcctg cagttttctc tgcacgtggc cgagggcatg gagtacctgg agagcaagaa 1440gcttgtgcac cgcgacctgg ccgcccgcaa catcctggtc tcagaggacc tggtggccaa 1500ggtcagcgac tttggcctgg ccaaagccga gcggaagggg ctagactcaa gccggctgcc 1560cgtcaagtgg acggcgcccg aggctctcaa acacgggaag ttcaccagca agtcggatgt 1620ctggagtttt ggggtgctgc tctgggaggt cttctcatat ggacgggctc cgtaccctaa 1680aatgtcactg aaagaggtgt cggaggccgt ggagaagggg taccgcatgg aaccccccga 1740gggctgtcca ggccccgtgc acgtcctcat gagcagctgc tgggaggcag agcccgcccg 1800ccggccaccc ttccgcaaac tggccgagaa gctggcccgg gagctacgca gtgcaggtgc 1860cccagcctcc gtctcagggc aggacgccga cggctccacc tcgccccgaa gccaggagcc 1920ctgaccccac ccggtggggc ccttggcccc agaggaccga gagagtggag agtgcggcgt 1980gggggcactg accaggccca aggagggtcc aggcgggcaa gtcatcctcc tggtgcccac 2040agcaggggct ggcccacgta gggggctctg ggcggcccgt ggacacccca gacctgcgaa 2100ggatgatcgc ccgataaaga cggattctaa ggactctaaa aaaaaaaaaa aaaaaaaaaa 2160aaa 2163544107DNAHomo sapiens 54gcgcaaccct ccggaagctg ccgccccttt ccccttttat gggaatactt tttttaaaaa 60aaaagagttc gctggcgcca ccccgtagga ctggccgccc taaaaccgtg ataaaggagc 120tgctcgccac ttctcacttc cgcttccttc cagtaaggag tcggggtctt ccccagtttt 180ctcagccagg cggcggcggc gactggcaat gtttggcctc aaaagaaacg cggtaatcgg 240actcaacctc tactgtgggg gggccggctt gggggccggc agcggcggcg ccacccgccc 300gggagggcga cttttggcta cggagaagga ggcctcggcc cggcgagaga tagggggagg 360ggaggccggc gcggtgattg gcggaagcgc cggcgcaagc cccccgtcca ccctcacgcc 420agactcccgg agggtcgcgc ggccgccgcc cattggcgcc gaggtccccg acgtcaccgc 480gacccccgcg aggctgcttt tcttcgcgcc cacccgccgc gcggcgccgc ttgaggagat 540ggaagccccg gccgctgacg ccatcatgtc gcccgaagag gagctggacg ggtacgagcc 600ggagcctctc gggaagcggc cggctgtcct gccgctgctg gagttggtcg gggaatctgg 660taataacacc agtacggacg ggtcactacc ctcgacgccg ccgccagcag aggaggagga 720ggacgagttg taccggcagt cgctggagat tatctctcgg taccttcggg agcaggccac 780cggcgccaag gacacaaagc caatgggcag gtctggggcc accagcagga aggcgctgga 840gaccttacga cgggttgggg atggcgtgca gcgcaaccac gagacggcct tccaaggcat 900gcttcggaaa ctggacatca aaaacgaaga cgatgtgaaa tcgttgtctc gagtgatgat 960ccatgttttc agcgacggcg taacaaactg gggcaggatt gtgactctca tttcttttgg 1020tgcctttgtg gctaaacact tgaagaccat aaaccaagaa agctgcatcg aaccattagc 1080agaaagtatc acagacgttc tcgtaaggac aaaacgggac tggctagtta aacaaagagg 1140ctgggatggg tttgtggagt tcttccatgt agaggaccta gaaggtggca tcaggaatgt 1200gctgctggct tttgcaggtg ttgctggagt aggagctggt ttggcatatc taataagata 1260gccttactgt aagtgcaata gttgactttt aaccaaccac caccaccacc aaaaccagtt 1320tatgcagttg gactccaagc tgtaacttcc tagagttgca ccctagcaac ctagccagaa 1380aagcaagtgg caagaggatt atggctaaca agaataaata catgggaaga gtgctcccca 1440ttgattgaag agtcactgtc tgaaagaagc aaagttcagt ttcagcaaca aacaaacttt 1500gtttgggaag ctatggagga ggacttttag atttagtgaa gatggtaggg tggaaagact 1560taatttcctt gttgagaaca ggaaagtggc cagtagccag gcaagtcata gaattgatta 1620cccgccgaat tcattaattt actgtagtgt taagagaagc actaagaatg ccagtgacct 1680gtgtaaaagt tacaagtaat agaactatga ctgtaagcct cagtactgta caagggaagc 1740ttttcctctc tctaattagc tttcccagta tacttcttag aaagtccaag tgttcaggac 1800ttttatacct gttatacttt ggcttggttt ccatgattct tactttatta gcctagttta 1860tcaccaataa tacttgacgg aaggctcagt aattagttat gaatatggat atcctcaatt 1920cttaagacag cttgtaaatg tatttgtaaa aattgtatat atttttacag aaagtctatt 1980tctttgaaac gaaggaagta tcgaatttac attagttttt ttcataccct tttgaacttt 2040gcaacttccg taattaggaa cctgtttctt acagcttttc tatgctaaac tttgttctgt 2100tcagttctag agtgtataca gaacgaattg atgtgtaact gtatgcagac tggttgtagt 2160ggaacaaatc tgataactat gcaggtttaa attttcttat ctgattttgg taagtattcc 2220ttagataggt ttttctttga aaacctggga ttgagaggtt gatgaatgga aattctttca 2280cttcattata tgcaagtttt caataattag gtctaagtgg agttttaagg ttactgatga 2340cttacaaata atgggctctg attgggcaat actcatttga gttccttcca tttgacctaa 2400tttaactggt gaaatttaaa gtgaattcat gggctcatct ttaaagcttt tactaaaaga 2460ttttcagctg aatggaactc attagctgtg tgcatataaa aagatcacat caggtggatg 2520gagagacatt tgatcccttg tttgcttaat aaattataaa atgatggctt ggaaaagcag 2580gctagtctaa ccatggtgct attattaggc ttgcttgtta cacacacagg tctaagccta 2640gtatgtcaat aaagcaaata cttactgttt tgtttctatt aatgattccc aaaccttgtt 2700gcaagttttt gcattggcat ctttggattt cagtcttgat gtttgttcta tcagacttaa 2760ccttttattt cctgtccttc cttgaaattg ctgattgttc tgctccctct acagatattt 2820atatcaattc ctacagcttt cccctgccat ccctgaactc tttctagccc ttttagattt 2880tggcactgtg aaacccctgc tggaaacctg agtgaccctc cctccccacc aagagtccac 2940agacctttca tctttcacga acttgatcct gttagcaggt ggtaatacca tgggtgctgt 3000gacactaaca gtcattgaga ggtgggagga agtccctttt ccttggactg gtatcttttc 3060aactattgtt ttatcctgtc tttgggggca atgtgtcaaa agtcccctca ggaattttca 3120gaggaaagaa cattttatga ggctttctct aaagtttcct ttgtatagga gtatgctcac 3180ttaaatttac agaaagaggt gagctgtgtt aaacctcaga gtttaaaagc tactgataaa 3240ctgaagaaag tgtctatatt ggaactaggg tcatttgaaa gcttcagtct cggaacatga 3300cctttagtct gtggactcca tttaaaaata ggtatgaata agatgactaa gaatgtaatg 3360gggaagaact gccctgcctg cccatctcag agccataagg tcatctttgc tagagctatt 3420tttacctatg tatttatcgt tcttgatcat aagccgctta tttatatcat gtatctctaa 3480ggacctaaaa gcactttatg tagtttttaa ttaatcttaa gatctggtta cggtaactaa 3540aaaagcctgt ctgccaaatc cagtggaaac aagtgcatag atgtgaattg gtttttaggg 3600gccccacttc ccaattcatt aggtatgact gtggaaatac agacaaggat cttagttgat 3660attttgggct tggggcagtg agggcttagg acaccccaag tggtttggga aaggaggagg 3720ggagtggtgg gtttataggg ggaggaggag gcaggtggtc taagtgctga ctggctacgt 3780agttcgggca aatcctccaa aagggaaagg gaggatttgc ttagaaggat ggcgctccca 3840gtgactactt tttgacttct gtttgtctta cgcttctctc agggaaaaac atgcagtcct 3900ctagtgtttc atgtacattc tgtggggggt gaacaccttg gttctggtta aacagctgta 3960cttttgatag ctgtgccagg aagggttagg accaactaca aattaatgtt ggttgtcaaa 4020tgtagtgtgt ttccctaact ttctgttttt cctgagaaaa aaaaataaat cttttattca 4080aatacaggga aaaaaaaaaa aaaaaaa 4107554102DNAHomo sapiens 55ttgaagacgt ggatggcggg aattctcgct tctggcctgg gtgagctaga agggagaagc 60aaggacattg gagtccctat caccggttgc ctagacaact tcatgggaag gcccttggga 120atctgagatg gagcaggcga accctttacg tccagatggc gagtccaaag gaggtgtttt 180agctcacttg gaaaggctag agacccaagt gagcagatcc cgtaaacagt ctgaagagct 240gcagagcgtg caggcccagg aaggtgctct tggaaccaag attcataaac taaggcgtct 300gcgagatgag ctgagggctg tggtgcggca ccggcgagcc agcgtgaaag catgtattgc 360caatgtagaa cccaaccaaa cagtggagat caatgagcaa gaagcattgg aagagaaatt 420ggaaaatgtg aaagccattc tgcaggcata tcattttaca ggcctcagtg gtaaactgac 480cagccgagga gtttgtgtct gcatcagtac tgcttttgag gggaacctat tggattccta 540ttttgtggac cttgtcatac agaaaccact ccggatacat caccattcag tcccagtctt 600cattcccctg gaagagatag ctgcaaaata tttacagacc aacatccagc acttcctgtt 660cagtctctgc gagtacctga atgcttactc tgggaggaag taccaggcag accggcttca 720gagtgacttt gcagccctcc tgactgggcc cttgcagaga aacccactgt gtaacttgct 780gtcatttact tacaaactgg atccaggggg tcagtccttc ccgttctgtg ctagattgct 840gtataaggac ctcacagcaa ctcttcccac tgacgtcacc gtgacatgtc aaggagtgga 900agtattatcc acttcatggg aggagcaacg agcatctcat gaaactctgt tctgtacgaa 960gcccttgcat caagtgtttg cctcatttac aagaaaagga gaaaagttgg atatgagtct 1020ggtctcctaa tagattgttt tcactgcact gggagcacat cagagaaata aatcccccct 1080cccctgccag gtgaaaggaa atattgcact ttctgttctc atgactaagg ggacaggagt 1140tccagaagaa cctttcaaga tgatcaggaa caccaggacg agggccgtct cacctcactc 1200ggaccacatg gagacctccc ttcaaaatgg gagccatgtc ctgccccacc aagccctgtc 1260tgaagtggag cttccccgcc tgtgctccct ccacagtccc ggaaagccca gcggcaaagg 1320cagctttgtc ccagctctgc caccctcctg ctcacagtgg tcagggcccc tcaggggcaa 1380ggacggcagg gattggaacg agggctctgg aaggactgtt cagccctatg cctaagaccc 1440ctatgctggg gacactacag gcacacacag gaatagcagg gccaccctca gagctcacac 1500atccacgaac aaatgaaggc tgaggaggtt tctaaaccta aagtccatga gtgtgcactt 1560caatccagga aggtcgggac ttccttcagt ttcaaaaaat aaattctccc ttccggtttg 1620gactgttgca ggctcgaggc cattcaggag ttgtccacca cctggtgggg cagtgtgaca 1680gaggggccat tggggaaggt ggctagctta tcccgcccct tcaagaagaa ggtcagcagc 1740tcccccttcc ccttcacaaa gatggggcct cgcctcacaa agcggaagcc gtactctcgg 1800aggatgactt gggtttcttc taccacctgg agagggaggg ggagcaagaa cgtggcgtta 1860cggggggagc ctagactgag ggcgggtggg ggctttgggt ggttggagcc gagcactgat 1920ccatgggtcc caagcagtac gggacactcc ccaaacctcc cagggccaag cccttccacc 1980cgtggcgagc agcgggtggg aaggagaacc ctggagtgac tggctggggg cctcctctca 2040tccagagact tctctcctag gatggccatg gtcacctggg tggcagcact gttacctgga 2100aactgccact gcctgctctt ctgtcccttt gcccctttcg tggagctttt ctgccagacg 2160ccactgagac agatcacaag gtattagaag gttcataccc aaaggtaggc catatgcatc 2220tagaacttca gcccagattt tgtggatggg tggaagtgtt tcttcctgtg ctgaggctag 2280ctattgcaga gattcttttc cacttgcccc acgtctctgc ctctggactt actgttcagg 2340gccagggtgg gaggcagggg cacgtgggaa agcactgttc cggttttgtt ctcatgccga 2400gtctgagcac gtgccagctg tgccactgga catacctgaa tgttgcccat gacccccgtg 2460gactccatcc tgctggctac attgactgta ttgccccaga tgtcgtagtg tggtttccgg 2520gctccgatga ccccagccag aaccccgcct ttgttcatgc ctagggtaga ggcataaagt 2580tcagcacagc cacaggccac accttgttat gggcctcaga agccatctcc tctccagacc 2640tgtaccacaa agctcctaat gtaacacatc attgtcctca ttcaacttgg ctgtatgcta 2700ttggagggtg gaaatcacat ctcctgttta tccgtgtgct tgttaggtgt cagccgccac 2760ccccccccca tatgcagatt tactcggcat ggtagtggcc agcttctaac acagctggta 2820tttcaagtct cctgggacct cactcaggaa tgataccccc tcagtagaag cagcaggtga 2880tcttaactcc tttcaaagag caggcctgtc tgggaagcca tgtcctcagc aggcacagca 2940acccctctgg aaatggatca caaactcact tctcagccag gcaggccaag cttctattgt 3000aacagtaggc acagtatagt cggatcatca catcagctgg gtttttggtt tagtcatcta 3060gagtcgtctg gactaaaggt ctttcaggtc tccttgccct gtgagtgcgt gaacctcccc 3120acccgaattg cctcagttgt cctgagcctc atgtctctcc tggtggtggg ccaggcccct 3180gcatgggaag ggagcctgct gcggggcagg ccagctgggg gtgctcacct atgcgcagca 3240tgaagttatt gaaggactgg ttgttgatgt tggtgagcgt atccttcatg gccagcgcga 3300agtcggccag gtcagccagg tgctgccagc gctctctctc ggacttgtct tcctgtgcca 3360ggggaccgtg gagaaagtgt caggggccgc tcactgcagc agcctgctct gctgccttcc 3420ctggcagtgt tctgggggtg gattccctac acctagatgt tcaaggcctt acttttcctc 3480ccacaaagga gtcgcagcca cgctagctct gacttgccac tgtgacaaag ttcacgtagc 3540aggtctaggc aaagactggg caattgagca gaggagacgg acctgtgagt ctgaccacga 3600ggcggacccc ttcaccttgg ctgggcctgg tcctggtcct taggttttgt caggttgtcc 3660ttgtttggat ccctcaacta ggtgataagc actggagggg gatgacccgc cttggacgtg 3720tttctttaac ctcatccata taatagggcc gtgggatggt tgtagaggta aagcaggatg 3780atggtgtttt aagaccagag cttgggacca gggctcctac acctaatttt ctctcctggt 3840agctgaacaa aggtctaaat tagcttaaca aaagaacagg ctgccgtcag ccagagttct 3900gaaggccatg ctttcagttt cccttgttga caattgctct ccagttccta tgaaagcaca 3960gagccttagg gggcctggcc acagaacaca accatcttag gcctgagctg tgaacagcag 4020ggggttgtgt gtctgttctg tttctctgct tgccgaactt tctcaataaa ccctatttct 4080tatttataaa aaaaaaaaaa aa 4102567998DNAHomo sapiens 56aggagtctgt cagctacgga ggacaatgac cttgcagaca ccaccgcctg agtgagaacc 60aggggtctgt gcctctcctc attccccgct cttgcccttg tcaagcctgc accagcatgt 120caggaacctc caaggagagt ctggggcatg gggggctgcc agggttgggc aagacctgct 180taacaaccat ggacacaaag ctgaacatgc tgaacgagaa ggtggaccag ctcctgcact 240tccaagaaga tgtcacagag aagttgcaga gcatgtgccg agacatgggc cacctggagc 300ggggcctgca caggctggag gcctcccggg caccgggccc gggcggggct gatggggttc 360cccacattga cacccaggct gggtggcccg aggtcctgga gctggtgagg gccatgcagc 420aggatgcggc ccagcacggt gccaggctgg aggccctctt caggatggtg gctgcggtgg 480acagggccat cgctttggtg ggggccacgt tccagaaatc aaaggtggcg gatttcctca 540tgcaggggcg tgtgccctgg aggagaggca gcccaggtga cagccctgag gagaataaag 600agcgagtgga agaagaggga ggaaaaccaa agcatgtgct gagcaccagt ggggtgcagt 660ctgatgccag ggagcctggg gaagagagcc agaaggcgga cgtgctggag gggacagcgg 720agaggctgcc ccccatcaga gcgtcagggc tgggagctga ccccgcccag gcagtggtct 780caccgggcca gggagatggt gttcctggcc cagcccaggc attccctggc cacctgcccc 840tgcccacaaa ggtggaagcc aaggctcctg agacacccag cgagaacctc aggactggcc 900tggaattggc tccagcaccc ggcagggtca atgtggtctc cccgagcctg gaggttgcac 960caggtgcagg acaaggagca tcgtccagca ggcctgaccc tgagccctta gaggaaggca 1020cgaggctgac tccagggcct ggccctcagt gcccagggcc tccagggctg ccagcccagg 1080ccagggcaac ccacagtggt ggagaaacac ctccaaggat ctccatccac atacaagaga 1140tggatactcc tggggagatg ctgatgacag gcaggggcag ccttggaccc accctcacca 1200cagaggctcc agcagctgcc cagccaggca agcagggccc acctgggacc gggcgctgcc 1260tccaagcccc tgggactgag cccggagaac agacccctga aggagccaga gagctctccc 1320cgctgcagga gagcagcagc cccgggggag tgaaggcaga ggaggagcaa agggctgggg 1380ccgagcctgg cacgagacca agcttggcca ggagtgacga caatgaccac gaggttgggg 1440ccctgggcct gcagcagggc aaaagcccag gggcgggaaa ccctgagcct gagcaggact 1500gtgcagccag ggctccggtg agagctgaag cagtaaggag gatgccccca ggcgccgagg 1560ctggcagcgt ggttctggat gacagtccgg ccccaccagc tccttttgaa caccgggtag 1620tgagcgtcaa ggagacctcc atctctgcgg gttacgaggt gtgccagcac gaagtcttgg 1680gagggggtcg gtttggccag gtccacaggt gcacagagaa gtccacaggc ctcccactgg 1740ctgccaagat catcaaagtg aagagcgcca aggaccggga ggacgtgaag aacgagatca 1800acatcatgaa ccagctcagc cacgtgaacc tgatccagct ctatgacgcc ttcgagagca 1860agcacagctg cacccttgtc atggagtacg tggacggggg tgagctcttc gaccggatca 1920cagatgagaa gtaccacctg actgagctgg atgtggtcct gttcaccagg cagatctgtg 1980agggtgtgca ttacctgcac cagcactaca tcctgcacct ggacctcaag ccggagaaca 2040tattgtgcgt caatcagaca ggacatcaaa ttaagatcat tgactttggg ctggccagaa 2100ggtacaagcc tcgagagaag ctgaaggtga acttcggcac tcctgagttc ctggccccag 2160aagtcgtcaa ttatgagttt gtctcattcc ccacagacat gtggagtgtg ggagtcatca 2220cctacatgct actcagtggc ttgtccccat ttctagggga aacagatgca gagaccatga 2280atttcattgt aaactgtagc tgggattttg atgctgacac ctttgaaggg ctctcggagg 2340aggccaagga ctttgtttcc cggttgctgg tcaaagagaa gagctgcaga atgagtgcca 2400cacagtgcct gaaacacgag tggctgaata atttgcctgc caaagcttca agatccaaaa 2460ctcgtctcaa atcccaacta ctgctgcaga aatacatagc tcaaagaaaa tggaagaaac 2520atttctatgt ggtgactgct gccaacaggt taaggaaatt tccaacttct ccctaatctt 2580caactctgct gctccaatgg gtccagaaat tactgaggcc agtggtgaag tgaagagatg 2640actcaaacat ttaaataatt tggctttttg gtattattga ttccacttat tttgtaaaaa 2700tggttatggc tgctgccttc cttgtggatg aaaagtggct gtaaagaagc ttcctaagaa 2760cgtttttttc tgccttgtaa gatcactacg tgtgaaatgc tctgagtacc tttcaaatat 2820acctactttt ggtggtaagt gtagggatgc tttaggtagg tactttgcat ctgtcgaatt 2880taaattctaa actcacactg attaaggaac tcagtagact actttgcagg ggccatgtta 2940ttcagtgtta tctcctccag tacaaagaat tcctagaatt ttgatttgct caggtgtgag 3000ctgacatttt attgtactac cccattcttg tgttaagcca tgtggattta ggacagtgat 3060cttcaaactt gctttaactt atgctccctt ttgagaatca gcatcacttg aaatgtcaaa 3120atatgtcaac tctcatagcc aaatcaaaga agtgatcatt ttgactgtgc tttttaaatc 3180tccacacacc tccacctctc tcctaattct gcctgtctta acccctctgt cttagttata 3240aatttctggt cttgtaagtc tggaagctga taggcaattt atgaaagaga taagaatgta 3300atgaggttcc gctttctgag aaacacagaa atgatacatc ctgagacata aaggaaagct 3360gctcttctgc tgcctcaggc tgtagcactc tcaatgttgt cactctacac atacactttc 3420tatatacatg tacagttgac ccttgaacag ggtttgaatt gcagtcaact taaatgtgga 3480ttttctttca cctttgtcac ccctgagaca gcaacaccat gctctcctct tcatcccact 3540ctgcagccta ctcaacagga agatgatgaa gatgaacacc tttatgatga tccactttca 3600cttaatgaat agtaaacata tgttttcctc cttatgattt tagtaacttt tctctagctt 3660actttattgt aagaatacag tatataagct gggtgtggtg gctcatgccc ataatcccag 3720cactttggga ggctgaggca ggcagatcac ttgaggtcag gagttcaaga ccagcctggc 3780caacacagtg aaaccccatc tctactaaaa atacaaaaat tagtggggcg tggtggcgga 3840tgcctgtaat gtcagctact ctggaggctg aggcaggaga actgcttgaa cctgggaggt 3900ggagtttgca gtgagccaag attgcaccac tgcactccag cctaggcaac agagcaagac 3960tccgtctcaa aaaaaaaaaa aaaaaagaat acagtatatg tatatataca cacacacaaa 4020cacacacaca cacgaacaca tatgtgtgta tgggtattaa ctgactgttt atattattga 4080tagggcttcc agtcaacatt aggctattag tagttaagtt tttggggaga caaaagttat 4140actcagattt tctactgcaa gggggtaggc actcctaacc ctcacattgt tcaagggtcc 4200actgtacatt taaacacttt tctatatgca ttagagtagc cctgtcatcc cttcactgaa 4260atcatactgt tctcaacatg gcaagcaact aacacttttt tttttttttg agacagggtc 4320tcactctgtt gcccaggctg cagtgcagtg gtgtgatctt ggctcactgt agcctccgcc 4380tcctgggctc aggcgatcat gagtacctgg gaccataggt gcccgctact acacccagct 4440aatttttgta tttttagtgg agatagggtt ttgccatgtt gcccaacctg gtcttgagct 4500caagcgatcc acctgcccca gcctcccaaa gtgctgggat tataggtgtg agccaccaca 4560cccagcttca actaacacat ttacgaactt gtatacatgt atatttagat actttaccaa 4620cttgtaaaat ggttaaagga gtactttatt atgaaaaaat atacaatctt taaaatttcc 4680ttacttctac atgatttttg tgctattccc atttttttcc tcaggtgagc agctttagtt 4740ttttattttt tttgagagag tcttcctctg tcacccaggc tggagtgcac tggtgtgttc 4800ttggctcact gcaacctctg cctcccgggt tcaagtgatc ttgtgcctca gcctcccagg 4860tagctgggat tacaggcgtg tgctgccacg cccagctaat ttttgtattt ttggtagaga 4920tggggttttg ccatgttggc caggctggtc tcgaactcct gacctcagat gatccacctg 4980tcttggcctc ccaaagagct gggaatatag gcatgagcca ctgtgcttgg cctcaggtga 5040gcagctttag tcaatgttgt gaattttaga ttttaattag acatgcaaca gtttcactac 5100ctttcaggat ttttgtcctg

taacagaggc tcttgctttt tgacagagag gtaggcaggt 5160ggagaggtta tcctgctgct gcagttctca agttgttaag tttcctctgg aaggctaacc 5220cttgttggga actaacagtt tcaataccag caagtctagg cctgctccaa gttggtcagc 5280tgaagaatga acatcagaag acacagctgc tgaaagttgt cctttgatga gacagtgata 5340gtgatttggt aaaatgtctt attttttaaa tgtcagttat ctttctttaa aaggtttttt 5400gagggcagcc tccagaagga gctagagagt atattttata gttctattgt ggttcatacc 5460ctgttttcga cttaagattc tggagaatgc tatgaaacat ctccccagaa aaagacagtt 5520aattaccata tctagagcag cactgcccaa caaaaatata gtacaggcta tacacataat 5580taaaacattt ctagtagctt ctctaacaaa acccattgaa agccaatttt aataatttat 5640ataacttagt gtatcaaaaa tatttcaata tgtaatcaac ataaaattga gatactttac 5700cagctactag ggaggctgag gccagagaat cacttgaacc cagggggtgg aggttgcagt 5760gagccaagat cacaccattg aactccagcc tgggcaacaa gagcaaaact ccgtctcaaa 5820aaaaaagaga tattttatat tctttttctc atactaagtc tcaaaaatct ggtatatttt 5880acacttaaaa acacatgtca aggctaggca tggtggctca catctgtaat cccagcactt 5940tgggaggcca aggtgggcag attgctggcc aacatggtaa aaccccatct ctaaaaatat 6000aaaaattagc tgggcgtggt ggcgcatacc tgtaatccca gctacttggg aggctaaggc 6060acaagaatca cttaaacagg aggcaggggt tgcagtgagc tgagatcaca ccactgcact 6120ccagcctggg tggcagagca aaactttgtc cccacccctg acaaaaaaca aacaaacaaa 6180caaaacaaaa aaaaacctgt caattcagat gctaggtttt catcagacgt acttaatctg 6240tatttagatt tcttaaaact tactgtggaa aatgtattta catactcaag ttgtttgaaa 6300cataactcac tgttttccaa taactgaagt atccactttt acatgtatta aaattaaata 6360aaattagaaa ttcagttctg cagttgcact agccacattt taagtgttta atagccacac 6420gtggttagtg gcatctatat tggacagggc agatctagag agaatcctgt atctaacaat 6480tttaattttt ttccctttat gctgttattc cttacctaga gaaacaattt ccctccaaag 6540ttcctttgag gggtctgttt aggccaggcc aacacaagtg acctatgtgg attttagcat 6600cctttttttg aaatttgagg ttttatgaag cttgagtttt tctggatatt tttagtaatt 6660tgctggtgtg tacttagctc aaatacttga ttgcaactgt gttgggtcaa ctatttctaa 6720tgggactttt ccatttgcat gtacagtcac tggaaactgc tgggcagaga aactctaaaa 6780ggtagttggg gcacactttt tccacctgtc agattggtga agaattggtg aggctgtggg 6840gaaaatggca ttctcccact tttgatggat atgtatccaa ataaaagtca ttcccatgct 6900ttctttcatc cagaaatttt atttctagaa atttatccct ccgtacttga acaattgtat 6960agagatttat tcaaaatgat gtttactata gcactgttgc taatggccca gtaaaaacaa 7020ccaacacatg cctattagtt tggttttagt taaatgaatt ttgccacatc catgtagtgg 7080aatacctcac agctgttata gatagatcta gatatactga aagccatttt ttcttaaatt 7140atagaatgta tatatggtat catcccattt gtgaagagac atatgcttat atgtgcatta 7200aaaaaccgta ggatatgcaa gaaacttaac agtggagtgt gaaaagtggg tgattgggag 7260agggggaatt ccacttttca tttatctttc tgaacctttt gaatcttttt tttttttttt 7320tttacaatga gcatgtattc cttttttttt ttttctttcc aagatggagt ctcactctgt 7380tgccaggctg gagtgcagtg gcgcaatctt ggcttactgc aacatccacc tcccgagttc 7440aagtgatttc tcctgcctca gcctcccaag tagctgggac tacaggcatg cgccaccacg 7500cccagctaat ttttgtgttt ttagtagaga tgggctttca ccatgctggc caggatggtc 7560tcgatctctt gacctcgtga tctgcccacc tcggcctccc aaagtgctgg gattacaggt 7620gtgagccact gcgcctggcc cgcatgtatt acatttataa ttaaaaattc acaactcaat 7680gtcaagtgtg aaccttgtgt tgaccctgat ttgagcaagc aataaaaaga tatttttgag 7740acatttagat tatgaatttc acatttgatg atagttacta ttaattttgt gaggtgtgat 7800attggcaatg tggttagatg acttcagaga aaaaggaagg tatagttaag caagtatggc 7860aacatctaat aacttgggtc taggtgatgt gtatgggttt cattatactg tcctctttac 7920tgttgtatgt atttgaaaac attcatgaca aaaaaacttt ttaatcagtt aaataaacca 7980tgaagaacgg ttaaagaa 7998577852DNAHomo sapiens 57ggcgctgagc gagctcggag cccgcgctgt gcgcctgcgg ccggggcgcc ccgccgagcg 60ccggtgcccc ggctcccggg ccgccttcgc cgcgcgggaa ggattcttca aaattaacag 120aaaccaattc gggccagctg aagagaaaaa ataaaggtgg ctcccggctg cctctgctgc 180agttcagagc aacttcagga gcttcccagc cgagagcttc aggacgcctt tcctgtccca 240ctggcccagt tgccacaaca aacaacagag aagacggtga ccatggggga tgtgaagctg 300gttgcctcgt cacacatttc caaaacctcc ctcagtgtgg atccctcaag agttgactcc 360atgcccctga cagaggcccc tgctttcatt ttgccccctc ggaacctctg catcaaagaa 420ggagccaccg ccaagttcga agggcgggtc cggggttacc cagagcccca ggtgacatgg 480cacagaaacg ggcaacccat caccagcggg ggccgcttcc tgctggattg cggcatccgg 540gggactttca gccttgtgat tcatgctgtc catgaggagg acaggggaaa gtatacctgt 600gaagccacca atggcagtgg tgctcgccag gtgacagtgg agttgacagt agaaggaagt 660tttgcgaagc agcttggtca gcctgttgtt tccaaaacct taggggatag attttcagct 720ccagcagtgg agacccgtcc tagcatctgg ggggagtgcc caccaaagtt tgctaccaag 780ctgggccgag ttgtggtcaa agaaggacag atgggacgat tctcctgcaa gatcactggc 840cggccccaac cgcaggtcac ctggctcaag ggaaatgttc cactgcagcc gagtgcccgt 900gtgtctgtgt ctgagaagaa cggcatgcag gttctggaaa tccatggagt caaccaagat 960gacgtgggag tgtacacgtg cctggtggtg aacgggtcgg ggaaggcctc gatgtcagct 1020gaactttcca tccaaggttt ggacagtgcc aataggtcat ttgtgagaga aacaaaagcc 1080accaattcag atgtcaggaa agaggtgacc aatgtaatct caaaggagtc gaagctggac 1140agtctggagg ctgcagccaa aagcaagaac tgctccagcc cccagagagg tggctcccca 1200ccctgggctg caaacagcca gcctcagccc ccaagggagt ccaagctgga gtcatgcaag 1260gactcgccca gaacggcccc gcagaccccg gtccttcaga agacttccag ctccatcacc 1320ctgcaggccg caagagttca gccggaacca agagcaccag gcctgggggt cctatcacct 1380tctggagaag agaggaagag gccagctcct ccccgtccag ccaccttccc caccaggcag 1440cctggcctgg ggagccaaga tgttgtgagc aaggctgcta acaggagaat ccccatggag 1500ggccagaggg attcagcatt ccccaaattt gagagcaagc cccaaagcca ggaggtcaag 1560gaaaatcaaa ctgtcaagtt cagatgtgaa gtttccggga ttccaaagcc tgaagtggcc 1620tggttcctgg aaggcacccc cgtgaggaga caggaaggca gcattgaggt ttatgaagat 1680gctggctccc attacctctg cctgctgaaa gcccggacca gggacagtgg gacatacagc 1740tgcactgctt ccaacgccca aggccagctg tcctgtagct ggaccctcca agtggaaagg 1800cttgccgtga tggaggtggc cccctccttc tccagtgtcc tgaaggactg cgctgttatt 1860gagggccagg attttgtgct gcagtgctcc gtacggggga ccccagtgcc ccggatcact 1920tggctgctga atgggcagcc catccagtac gctcgctcca cctgcgaggc cggcgtggct 1980gagctccaca tccaggatgc cctgccggag gaccatggca cctacacctg cctagctgag 2040aatgccttgg ggcaggtgtc ctgcagcgcc tgggtcaccg tccatgaaaa gaagagtagc 2100aggaagagtg agtaccttct gcctgtggct cccagcaagc ccactgcacc catcttcctg 2160cagggcctct ctgatctcaa agtcatggat ggaagccagg tcactatgac tgtccaagtg 2220tcagggaatc caccccctga agtcatctgg ctgcacaatg ggaatgagat ccaagagtca 2280gaggacttcc actttgaaca gagaggaact cagcacagcc tttgtatcca ggaagtgttc 2340ccggaggaca cgggcacgta cacctgcgag gcctggaaca gcgctggaga ggtccgcacc 2400caggccgtgc tcacggtaca agagcctcac gatggcaccc agccctggtt catcagtaag 2460cctcgctcag tgacagcctc cctgggccag agtgtcctca tctcctgcgc catagctggt 2520gacccctttc ctaccgtgca ctggctcaga gatggcaaag ccctctgcaa agacactggc 2580cacttcgagg tgcttcagaa tgaggacgtg ttcaccctgg ttctaaagaa ggtgcagccc 2640tggcatgccg gccagtatga gatcctgctc aagaaccggg ttggcgaatg cagttgccag 2700gtgtcactga tgctacagaa cagctctgcc agagcccttc cacgggggag ggagcctgcc 2760agctgcgagg acctctgtgg tggaggagtt ggtgctgatg gtggtggtag tgaccgctat 2820gggtccctga ggcctggctg gccagcaaga gggcagggtt ggctagagga ggaagacggc 2880gaggacgtgc gaggggtgct gaagaggcgc gtggagacga ggcagcacac tgaggaggcg 2940atccgccagc aggaggtgga gcagctggac ttccgagacc tcctggggaa gaaggtgagt 3000acaaagaccc tatcggaaga cgacctgaag gagatcccag ccgagcagat ggatttccgt 3060gccaacctgc agcggcaagt gaagccaaag actgtgtctg aggaagagag gaaggtgcac 3120agcccccagc aggtcgattt tcgctctgtc ctggccaaga aggggacttc caagaccccc 3180gtgcctgaga aggtgccacc gccaaaacct gccaccccgg attttcgctc agtgctgggt 3240ggcaagaaga aattaccagc agagaatggc agcagcagtg ccgagaccct gaatgccaag 3300gcagtggaga gttccaagcc cctgagcaat gcacagcctt cagggccctt gaaacccgtg 3360ggcaacgcca agcctgctga gaccctgaag ccaatgggca acgccaagcc tgccgagacc 3420ctgaagccca tgggcaatgc caagcctgat gagaacctga aatccgctag caaagaagaa 3480ctcaagaaag acgttaagaa tgatgtgaac tgcaagagag gccatgcagg gaccacagat 3540aatgaaaaga gatcagagag ccaggggaca gccccagcct tcaagcagaa gctgcaagat 3600gttcatgtgg cagagggcaa gaagctgctg ctccagtgcc aggtgtcttc tgacccccca 3660gccaccatca tctggacgct gaacggaaag accctcaaga ccaccaagtt catcatcctc 3720tcccaggaag gctcactctg ctccgtctcc atcgagaagg cactgcctga ggacagaggc 3780ttatacaagt gtgtagccaa gaatgacgct ggccaggcgg agtgctcctg ccaagtcacc 3840gtggatgatg ctccagccag tgagaacacc aaggccccag agatgaaatc ccggaggccc 3900aagagctctc ttcctcccgt gctaggaact gagagtgatg cgactgtgaa aaagaaacct 3960gcccccaaga cacctccgaa ggcagcaatg ccccctcaga tcatccagtt ccctgaggac 4020cagaaggtac gcgcaggaga gtcagtggag ctgtttggca aagtgacagg cactcagccc 4080atcacctgta cctggatgaa gttccgaaag cagatccagg aaagcgagca catgaaggtg 4140gagaacagcg agaatggcag caagctcacc atcctggccg cgcgccagga gcactgcggc 4200tgctacacac tgctggtgga gaacaagctg ggcagcaggc aggcccaggt caacctcact 4260gtcgtggata agccagaccc cccagctggc acaccttgtg cctctgacat tcggagctcc 4320tcactgaccc tgtcctggta tggctcctca tatgatgggg gcagtgctgt acagtcctac 4380agcatcgaga tctgggactc agccaacaag acgtggaagg aactagccac atgccgcagc 4440acctctttca acgtccagga cctgctgcct gaccacgaat ataagttccg tgtacgtgca 4500atcaacgtgt atggaaccag tgagccaagc caggagtctg aactcacaac ggtaggagag 4560aaacctgaag agccgaagga tgaagtggag gtgtcagatg atgatgagaa ggagcccgag 4620gttgattacc ggacagtgac aatcaatact gaacaaaaag tatctgactt ctacgacatt 4680gaggagagat taggatctgg gaaatttgga caggtctttc gacttgtaga aaagaaaact 4740cgaaaagtct gggcagggaa gttcttcaag gcatattcag caaaagagaa agagaatatc 4800cggcaggaga ttagcatcat gaactgcctc caccacccta agctggtcca gtgtgtggat 4860gcctttgaag aaaaggccaa catcgtcatg gtcctggaga tcgtgtcagg aggggagctg 4920tttgagcgca tcattgacga ggactttgag ctgacggagc gtgagtgcat caagtacatg 4980cggcagatct cggagggagt ggagtacatc cacaagcagg gcatcgtgca cctggacctc 5040aagccggaga acatcatgtg tgtcaacaag acgggcacca ggatcaagct catcgacttt 5100ggtctggcca ggaggctgga gaatgcgggg tctctgaagg tcctctttgg caccccagaa 5160tttgtggctc ctgaagtgat caactatgag cccatcggct acgccacaga catgtggagc 5220atcggggtca tctgctacat cctagtcagt ggcctttccc ccttcatggg agacaacgat 5280aacgaaacct tggccaacgt tacctcagcc acctgggact tcgacgacga ggcattcgat 5340gagatctccg acgatgccaa ggatttcatc agcaatctgc tgaagaaaga tatgaaaaac 5400cgcctggact gcacgcagtg ccttcagcat ccatggctaa tgaaagatac caagaacatg 5460gaggccaaga aactctccaa ggaccggatg aagaagtaca tggcaagaag gaaatggcag 5520aaaacgggca atgctgtgag agccattgga agactgtcct ctatggcaat gatctcaggg 5580ctcagtggca ggaaatcctc aacagggtca ccaaccagcc cgctcaatgc agaaaaacta 5640gaatctgaag aagatgtgtc ccaagctttc cttgaggctg ttgctgagga aaagcctcat 5700gtaaaaccct atttctctaa gaccattcgc gatttagaag ttgtggaggg aagtgctgct 5760agatttgact gcaagattga aggataccca gaccccgagg ttgtctggtt caaagatgac 5820cagtcaatca gggagtcccg ccacttccag atagactacg atgaggacgg gaactgctct 5880ttaattatta gtgatgtttg cggggatgac gatgccaagt acacctgcaa ggctgtcaac 5940agtcttggag aagccacctg cacagcagag ctcattgtgg aaacgatgga ggaaggtgaa 6000ggggaagggg aagaggaaga agagtgaaac aaagccagag aaaagcagtt tctaagtcat 6060attaaaagga ctatttctct aaaactcaaa aaaaaaaaaa aaactcaaga tagtaaaagc 6120acctagtgtg atagattatc ggttaggtca tttgtgggtt gattcttcag aaacagcagt 6180tgatacctag cagcgttatt gatgggcatt aatctatgtt agttggcacc ttaagatact 6240agtgcagcta gatttcattt agggaaatca ccagtaactt gactgaccaa ttgattttag 6300agagaaagta accaaaccaa atatttatct gggcaaagtc ataaattctc cacttgaatg 6360cgctcatgaa aaataaggcc aaaacaagag ttctgggcca cagctcagcc cagagggttc 6420ctggggatgg gaggcctctc tctccccacc ccctgactct agagaactgg gttttctccc 6480agtactccag caattcattt ctgaaagcag ttgagccact ttattccaaa gtacactgca 6540gatgttcaaa ctctccattt ctctttcccc ttccacctgc cagttttgct gactctcaac 6600ttgtcatgag tgtaagcatt aaggacatta tgcttcttcg attctgaaga caggtccctg 6660ctcatggatg actctggctt ccttaggaaa atatttttct tccaaaatca gtaggaaatc 6720taaacttatc ccctctttgc agatgtctag cagcttcaga catttggtta agaacccatg 6780ggaaaaaaaa aatccttgct aatgtggttt cctttgtaaa ccaggattct tatttgtgct 6840gttatagaat atcagctctg aacgtgtggt aaagattttt gtgtttgaat ataggagaaa 6900tcagtttgct gaaaagttag tcttaattat ctattggcca cgatgaaaca gatttcaact 6960gataaagagc tggagaactc catgtacttt ggaatctcct ccaagatagc cagagtttaa 7020tacatcttca ttctcaacac tctccaaaga acttgaccta ccttatgggt tccatatttt 7080tcttcttaaa tgtgcatcaa tcatgccttg cccccaacct ttaaatatat tcttagacct 7140ggtaaatgca ctcagacttg cgtctttagg aatttttaac tttctttcac tacattggca 7200cttaaatttt ttctttataa agctttttga aggtcataaa caaagaccat aattgatgat 7260agacctaata catttcctct gtgtgtgtgt gtaacattcc aaatactttt tttttctttt 7320ccactgtttg taaggtgcaa caatttaata tttttaaggg actttttaag agttccttaa 7380gaaccaattt aaaattactt cagtgcaatc ctacacagta tcaacattag aattttgata 7440ttagtcttat gttatcttcc attctatttt tatctgcttt ttgctgctag tttcaaactg 7500ccagtatttt tccttttgct tttaaaatag ttacaatatt tttcatgata gccacagtat 7560tgccacagtt tattataata aagggttttt atttgattta gcgcattcaa agcttttttc 7620tatcactttt gtgttcagaa tataaccttt gtgtgcgtgt atgttgtgtg tgtgcatgtg 7680tggcgtatat gtgtgttaca ggttaatgcc ttcttggaat tgtgttaatg ttctcttggt 7740ttattatgcc atcagaatgg taaatgagaa cactacaact gtagtcagct cacaattttt 7800aaataaagga taccacagtg catgctgttt gttcaaaaaa aaaaaaaaaa aa 7852586230DNAHomo sapiens 58ctagatcgaa agtcctttgg taatgatgtg tcatacattc tagtcatcaa agacaccatt 60ttctgggcct gaagtgttct gctggttttt ggaggaatga gaatccaatc tctcataagc 120cggattcaga aaataggtca tcgatgaaac atctgtatgg attatttcac tataatccta 180tgatgcttgg acttgaatca cttccagatc ccacagacac ctgggaaatt atagagacca 240ttggtaaagg cacctatggc aaagtctaca aggtaactaa caagagagat gggagcctgg 300ctgcagtgaa aattctggat ccagtcagtg atatggatga agaaattgag gcagaataca 360acattttgca gttccttcct aatcatccca atgttgtaaa gttttatggg atgttttaca 420aagcggatca ctgtgtaggg ggacagctgt ggctggtcct ggagctgtgt aatgggggct 480cagtcactga gcttgtcaaa ggtctactca gatgtggcca gcggttggat gaagcaatga 540tctcatacat cttgtacggg gccctcttgg gccttcagca tttgcacaac aaccgaatca 600tccaccgtga tgtgaagggg aataacattc ttctgacaac agaaggagga gttaagctcg 660ttgactttgg tgtttcagct caactcacca gtacacgtct gcggagaaac acatctgttg 720gcaccccgtt ctggatggcc cctgaggtca ttgcctgtga gcagcagtat gactcttcct 780atgacgctcg ctgtgacgtc tggtccttgg ggatcacagc tattgaactg ggggatggag 840accctcccct ctttgacatg catcctgtga aaacactctt taagattcca agaaatcctc 900cacctacttt acttcatcca gaaaaatggt gtgaagaatt caaccacttt atttcacagt 960gtcttattaa ggattttgaa aggcgacctt ccgtcacaca tctccttgac cacccattta 1020ttaaaggagt acatggaaaa gttctgtttc tgcaaaaaca gctggccaag gttctccaag 1080accagaagca tcaaaatcct gttgctaaaa ccaggcatga gaggatgcat accagaagac 1140cttatcatgt ggaagatgct gaaaaatact gccttgagga tgatttggtc aacctagagg 1200ttctggatga ggatacaatt atccatcagt tgcagaaacg ttatgcagac ttgctaattt 1260acacatatgt tggagacatc ttaattgcct taaacccctt ccagaatcta agcatatact 1320ctccacagtt ttccagactt tatcatgggg tgaaacgcgc ctccaatccc ccccacatat 1380ttgcatcagc agatgctgct taccagtgca tggttactct cagcaaagac cagtgcattg 1440tcatcagcgg agagagtggc tctgggaaga cagaaagcgc ccacctgatt gttcagcatt 1500tgactttctt gggaaaggcc aataatcaga ccttgagaga gaaaattcta caagtcaact 1560ccctggtgga agcctttggg aactcatgca ctgccatcaa tgacaactcg agccgttttg 1620gaaaatatct ggaaatgatg tttacaccaa ctggagttgt gatgggggca agaatctctg 1680aatatctcct ggaaaaatcc agagttataa aacaggcagc gagagagaaa aattttcata 1740tattttacta tatttatgct ggtcttcatc accaaaagaa gctttctgat ttcagacttc 1800ctgaggaaaa acctcctagg tacatagctg atgaaactgg aagggtgatg cacgacataa 1860cttccaagga gtcttacaga agacaattcg aagcaattca gcattgcttc aggattatag 1920ggttcacgga caaagaggtg cactcagtgt acagaatttt ggctgggatt ttgaatattg 1980ggaacattga gttcgcagct atttcctctc aacatcagac tgataaaagt gaggtgccca 2040atgctgaagc tttgcaaaat gctgcctctg ttctgtgcat tagccctgaa gagctccagg 2100aggccctcac ctcccactgt gtggtcaccc ggggcgagac catcatccgt gccaacactg 2160tagacagggc tgcggacgtt cgagacgcca tgtccaaagc cctgtatggg aggctcttca 2220gctggattgt gaatcgcatt aatacactcc tgcagccaga cgaaaacata tgtagtgcag 2280gaggtggaat gaatgtgggg atcttggata tctttggatt cgagaatttt cagagaaatt 2340catttgagca gctctgcata aacatcgcca atgagcaaat ccagtactat ttcaatcagc 2400atgtttttgc tcttgagcag atggaatatc agaatgaagg cattgatgct gtacccgtgg 2460aatatgagga caaccgcccg ctcttggaca tgttcctcca gaaacccctg ggactgcttg 2520cacttttgga tgaggaaagt cggtttcccc aagcaactga ccagaccctg gttgataaat 2580ttgaagataa tctacgatgc aaatacttct ggaggcccaa aggagtggaa ctgtgctttg 2640gcattcagca ttatgctgga aaggtattat atgatgcttc tggggttctt gagaaaaata 2700gagacactct ccctgccgat gtggttgtgg tcctgagaac gtcagaaaac aagcttcttc 2760agcagctctt ctcaatccct ctgaccaaaa caggtaattt ggcccagaca agagctagga 2820taacagtggc ctcaagttct ttgcctccac atttcagtgc tgggaaagcc aaggtggaca 2880ctctggaggt gatacggcat ccggaagaaa ccaccaacat gaagaggcaa actgtggctt 2940cttacttccg gtattctctg atggacctgc tctccaaaat ggtggttgga cagccccact 3000ttgtgcgctg cattaaaccc aatgatgacc gagaggccct gcagttctct cgagagaggg 3060tgctggccca gctccgctcc acagggattc tggagacagt cagcatccgc cgccagggct 3120attcccaccg catccttttt gaagaatttg tgaaaaggta ttattacttg gcattcacag 3180cacatcaaac acctcttgct agcaaagaga gctgtgtggc tatcttggaa aagtccagat 3240tagatcactg ggtactggga aaaacaaagg tttttctcaa atattaccat gttgagcaat 3300taaatttgct gcttcgagaa gtcataggca gagtggttgt gctgcaggca tataccaagg 3360ggtggcttgg agccaggaga tacaaaaggg tcagagagaa gagagagaag ggagccattg 3420ccatccagtc agcctggaga ggatatgatg ctcggaggaa atttaagaaa ataagcaaca 3480gaaggaatga gtctgctgct cataatcaag caggggacac ttcaaaccaa agcagtgggc 3540cacattcccc cgtcgcagca ggtacgaggg gaagtgccga ggttcaagac tgcagcgagc 3600ctggtgacca taaagttctc aggggctctg tacatcgtag gagccattca caagcagaat 3660ccaacaatgg ccgtacacag acttcaagca actctcctgc tgtcacagag aaaaatgggc 3720attcacaagc ccagagttct ccaaaagggt gcgatatctt cgcaggacat gcaaacaagc 3780actcggtttc tgggactgat ttgctgtctt ctcggatatg ccatcctgct ccagatcagc 3840aaggattgag tctctgggga gcccctcaaa agcctggttc agaaaatggt cttgcacaga 3900agcatcgaac acctcgccga cgatgtcagc agcccaaaat gctgagtagc cctgaggaca 3960ccatgtacta taaccagtta aatggaactc tagaatatca agggagcaag aggaagccaa 4020gaaaacttgg ccaaatcaaa gtacttgatg gggaagatga atattacaaa tctctgtcac 4080cagtggactg tatccctgag gagaacaact cagcccaccc ttcctttttt tcttcatcct 4140caaaaggaga ctcttttgct caacattaaa ttgtgcttcc taaccctaaa tctgtccaga 4200gtaggaacat tcatggtaat cgactgtctg tcattgcgta

agaaagcact gatatggggt 4260cagcttcttt ggacatatgg tccatgcctg aaccttactg aaccacttgc agattccaaa 4320acatcttatc ctatcctcta ccactctccc acatgtgttg tgcagcctga gctgggcgct 4380gccttccttt ctcatcccat ggggccctgt gggacactga gaacaccttt acaatagttt 4440aaacagtcat tcatgccccc agtgtctagg aagataacag ccagtctcac cccagtctaa 4500tcatggaccc tgataatatt gcttgatttt tcctatcaag ttacttttca atccattcag 4560aatctgcccc agtggagacc caggagttcc tttcctgcac tcttctccat cctcccacct 4620ttgctgggct tttctatcac tcccacctcc cccagagtca gggctccatt gctgagtgcc 4680ccatcctgga ggattggccc caagatctcc tagaacagga taattgcctg tgtttaggca 4740gataggccta aatctttcag attctttcta caaggcaaat aacccctctc ttgttaatta 4800tgatgctgag aaagcctctg tctctttatt tcaccttgcc aagacaccca cactactttg 4860gtgatgaaaa gaaaggaatg agagggaaag tttggacctg tcactttggt gacagggaaa 4920gtccaggtca ctttattctg taactctcca ttcactggtc aaataactcc atgaggctat 4980cagtggctac agtggaagga cctgatcttg tccatctttg tgtgcacaga gcctagcaca 5040gggcttggta gagggtatat ctagtgaatg gagaatacat ggagaaactt aactaagtta 5100cacaagcata tctgacagga atgttacctt caattgtatg ttacatatga ttagtcactt 5160ttcatacact ataacctctg atttttcact caagtttggg ctgattatat tgtaatgatg 5220ttagataata ctcaacatga ttcagtatga caaacttttt tgagcaccta ctttatataa 5280aacatgacaa attgcagtgt gatgtaatca aaaacaaaga agccctataa gaccatttct 5340ctagaacaga tgttcttaat atttttctta ctctaaaata tgtggtagat agtatgcaag 5400aaaagccggg tgcggtggct caggcctgta atcccagcac tttgggaggc caagatgggc 5460ggatcatgaa gtcaggagtt cgagaccagc ctgaccaaca tggtgaaacc ccgtctctac 5520taaaaaaaat aatgataata caaaaattag cccagcatgg tggtgcatac ctgtaatccc 5580agctactcag gaggctgacg caggagaatc acttgaaccc gggaagcaaa ggttgcagtc 5640agctgagagc gcaccactgc actccagcct gggcgacagg gcaagactct gtctcaaaaa 5700aaaaaaaaaa aaaaaaaaaa agagatagta tgcaagaaga cacctaaatt ttgagagaaa 5760taaccttgaa gaaaatcttg ttatcagagt tttgaaaggg agcacattaa taggcctttt 5820atgaagataa ataatgaaat gaggtattta aagatctcag aaattgtaat tttacaagta 5880aaataaatat agccaatttt tcaatagctg aacttcaccc aaaaggtaat gtttataagt 5940agagcagaaa aaatgcagat aaattttatt ttattgttta aaaaataatg tgtagaatat 6000ataaattttt tatgttactg ttaatatacg agtgcttttg gaagtttcac ttttgtcact 6060gattgtctac ttttggtttg ataatatgag ctgcttttca aattgttgaa tggaaatgtt 6120cataactccc tgcttgtccg tgcacaatgt aattctaaac ctggcttgtt tctcatttaa 6180atatatctat aaataaactt aaaaagaaaa caaaaaaaaa aaaaaaaaaa 6230591896DNAHomo sapiens 59ctctttctcg cctcagggcc tttgtactgg cggttccttc cgccggacac gtcgggtttc 60ctcgtttttg cggactggcg ctttctgatt tcagagactc tccgcaacag aaccatctca 120agtgggtcta cctcctcgcc tttttttgtt gttgttgttg cttggctgcg cttctgacag 180ggcaggccgt gatgatgttt gtttatgagt taggtctgac tgttcgttgg tgcttaagat 240ccccaccggg tccctagggc ctgtgcgtac cgcgcacctg tgcacgtcct gcgcgcagct 300gcaggcgact ccgctctggc tcgtcgctgc tgtttcctgc tgggggtgcc gaccctgtcc 360cacgctagct gggtgacttc ccccaaccgc agagacagcg gcgacccggg gcctcagacc 420tgcccccgca tctcgccggc gccaggcagt gggaagtcag gttcttccgc cacctcccag 480ccaggactct gccaccctcc ctcaggatgc ctgagggccc cgagctgcac ctggccagcc 540agtttgtgaa tgaggcctgc agggcgctgg tgttcggcgg ctgcgtggag aagtcctctg 600tcagccgcaa ccctgaggtg ccctttgaga gcagtgccta ccgcatctca gcttcagccc 660gcggcaagga gctgcgcctg atactgagcc ctctgcctgg ggcccagccc caacaggagc 720cactggccct ggtcttccgc ttcggcatgt ccggctcttt tcagctggtg ccccgcgagg 780agctgccacg ccatgcccac ctgcgctttt acacggcccc gcctggcccc cggctcgccc 840tatgtttcgt ggacatccgc cggttcggcc gctgggacct tgggggaaag tggcagccgg 900gccgcgggcc ctgtgtcttg caggagtacc agcagttcag ggagaatgtg ctacgaaacc 960tagcggataa ggcctttgac cggcccatct gcgaggccct cctggaccag aggttcttca 1020atggcattgg caactatctg cgggcagaga tcctgtaccg gctgaagatc cccccctttg 1080agaaggcccg ctcggtcctg gaggccctgc agcagcacag gccgagcccg gagctgaccc 1140tgagccagaa gataaggacc aagctgcaga atccagacct gctggagcta tgtcactcag 1200tgcccaagga agtggtccag ttggggggca aaggctacgg gtcagagagc ggggaggagg 1260actttgctgc ctttcgagcc tggctgcgct gctatggcat gccaggcatg agctccctgc 1320aggaccggca tggccgtacc atctggttcc agggggatcc tggaccgttg gcacccaaag 1380ggcgcaagtc ccgcaaaaag aaatccaagg ccacacagct gagtcctgag gacagagtgg 1440aggacgcttt gcctccaagc aaggcccctt ccaggacacg aagggcaaag agagaccttc 1500ctaagaggac tgcaacccag cggcctgagg ggaccagcct ccagcaggac ccagaagctc 1560ccacagtgcc caagaagggg aggaggaagg ggcgacaggc agcctctggc cactgcagac 1620cccggaaggt caaggctgac atcccatcct tggaaccaga ggggacctca gcctcttagc 1680aggaggctct ccttgcttgc actcaccctt tcttattgtc ttgccctgca tctgggggtc 1740tgaatttttg ggagcaggca atatctgaag gtgcaaacag gccctacggc tgttccctgc 1800acaactctca tggttttaat tgtaccccat cttccacatc tttaaagctc atgtgaaaaa 1860tgctgcattt ttaataaact gatacatttg aacttc 1896602161DNAHomo sapiens 60gcgacggtta aacggggccc aaggcagggg tggcgggtca gtgctgctcg ggggcttctc 60catccaggtc cctggagttc ctggtccctg gagctccgca cttggcggcg caacctgcgt 120gaggcagcgc gactctggcg actggccggc catgccttcc cgggctgagg actatgaagt 180gttgtacacc attggcacag gctcctacgg ccgctgccag aagatccgga ggaagagtga 240tggcaagata ttagtttgga aagaacttga ctatggctcc atgacagaag ctgagaaaca 300gatgcttgtt tctgaagtga atttgcttcg tgaactgaaa catccaaaca tcgttcgtta 360ctatgatcgg attattgacc ggaccaatac aacactgtac attgtaatgg aatattgtga 420aggaggggat ctggctagtg taattacaaa gggaaccaag gaaaggcaat acttagatga 480agagtttgtt cttcgagtga tgactcagtt gactctggcc ctgaaggaat gccacagacg 540aagtgatggt ggtcataccg tattgcatcg ggatctgaaa ccagccaatg ttttcctgga 600tggcaagcaa aacgtcaagc ttggagactt tgggctagct agaatattaa accatgacac 660gagttttgca aaaacatttg ttggcacacc ttattacatg tctcctgaac aaatgaatcg 720catgtcctac aatgagaaat cagatatctg gtcattgggc tgcttgctgt atgagttatg 780tgcattaatg cctccattta cagcttttag ccagaaagaa ctcgctggga aaatcagaga 840aggcaaattc aggcgaattc cataccgtta ctctgatgaa ttgaatgaaa ttattacgag 900gatgttaaac ttaaaggatt accatcgacc ttctgttgaa gaaattcttg agaacccttt 960aatagcagat ttggttgcag acgagcaaag aagaaatctt gagagaagag ggcgacaatt 1020aggagagcca gaaaaatcgc aggattccag ccctgtattg agtgagctga aactgaagga 1080aattcagtta caggagcgag agcgagctct caaagcaaga gaagaaagat tggagcagaa 1140agaacaggag ctttgtgttc gtgagagact agcagaggac aaactggcta gagcagaaaa 1200tctgttgaag aactacagct tgctaaagga acggaagttc ctgtctctgg caagtaatcc 1260agaacttctt aatcttccat cctcagtaat taagaagaaa gttcatttca gtggggaaag 1320taaagagaac atcatgagga gtgagaattc tgagagtcag ctcacatcta agtccaagtg 1380caaggacctg aagaaaaggc ttcacgctgc ccagctgcgg gctcaagccc tgtcagatat 1440tgagaaaaat taccaactga aaagcagaca gatcctgggc atgcgctagc caggtagaga 1500gacacagagc tgtgtacagg atgtaatatt accaaccttt aaagactgat attcaaatgc 1560tgtagtgttg aatacttggt tccatgagcc atgcctttct gtatagtaca catgatattt 1620cggaattggt tttactgttc ttcagcaact attgtacaaa atgttcacat ttaatttttc 1680tttcttcttt taagaacata ttataaaaag aatactttct tggttgggct tttaatcctg 1740tgtgtgatta ctagtaggaa catgagatgt gacattctaa atcttgggag aaaaaataat 1800gttaggaaaa aaatatttat gcaggaagag tagcactcac tgaatagttt taaatgactg 1860agtggtatgc ttacaattgt catgtctaga tttaaatttt aagtctgaga ttttaaatgt 1920ttttgagctt agaaaaccca gttagatgca atttggtcat taataccatg acatcttgct 1980tataaatatt ccattgctct gtagttcaaa tctgttagct ttgtgaaaat tcatcactgt 2040gatgtttgta ttcttttttt ttttctgttt aacagaatat gagctgtctg tcatttacct 2100acttctttcc cactaaataa aagaattctt cagtttccct gtaaaaaaaa aaaaaaaaaa 2160a 2161611139DNAHomo sapiens 61gggcggggcc tcggcgtggt aggcgcgctg cgtaaagagg cctgcagtcc cgcggcgcgg 60ggcaggttcc gggctgctta ggttggcacc ggtccgtggt ccccgggggc gcagtcgcag 120cgctcccgcc ctccaggcgt cagcgagtgc gcggtccagt gcggccggaa cctggcgcaa 180ctcctagagc ggtccttggg gagacgcggg tcccagtcct gcggctccta ctggggagtg 240cgctggtcgg aagattgctg gactcgctga agagagacta cgcaggaaag ccccagccac 300ccatcaaatc agagagaagg aatccacctt cttacgctat ggcaggtaag aaagtactca 360ttgtctatgc acaccaggaa cccaagtctt tcaacggatc cttgaagaat gtggctgtag 420atgaactgag caggcagggc tgcaccgtca cagtgtctga tttgtatgcc atgaaccttg 480agccgagggc cacagacaaa gatatcactg gtactctttc taatcctgag gttttcaatt 540atggagtgga aacccacgaa gcctacaagc aaaggtctct ggctagcgac atcactgatg 600agcagaaaaa ggttcgggag gctgacctag tgatatttca gttcccgctg tactggttca 660gcgtgccagc catcctgaag ggctggatgg atagggtgct gtgccagggc tttgcctttg 720acatcccagg attctacgat tccggtttgc tccagggtaa actagcgctc ctttccgtaa 780ccacgggagg cacggccgag atgtacacga agacaggagt caatggagat tctcgatact 840tcctgtggcc actccagcat ggcacattac acttctgtgg atttaaagtc cttgcccctc 900agatcagctt tgctcctgaa attgcatccg aagaagaaag aaaggggatg gtggctgcgt 960ggtcccagag gctgcagacc atctggaagg aagagcccat cccctgcaca gcccactggc 1020acttcgggca ataactctgt ggcacgtggg catcacgtaa gcagcacact aggaggccca 1080ggcgcaggca aagagaagat ggtgctgtca tgaaataaaa ttacaacata gctacctgg 1139621939DNAHomo sapiens 62aggaaggagg ggtggcctga cccctcggca gtccctcccc tcagcctttc cccaaattgc 60tacttctctg gggctccagg tcctgcttgt gctcagctcc agctcactgg ctggccaccg 120agacttctgg acaggaaact gcaccatcct cttctcccag caagggggct ccagagactg 180cccacccagg aagtctggtg gcctggggat ttggacagtg ccttggtaat gaccagggct 240ccaggaagag atgtccttgt ggctgggggc ccctgtgcct gacattcctc ctgactctgc 300ggtggagctg tggaagccag gcgcacagga tgcaagcagc caggcccagg gaggcagcag 360ctgcatcctc agagaggaag ccaggatgcc ccactctgct gggggtactg caggggtggg 420gctggaggct gcagagccca cagccctgct caccagggca gagccccctt cagaacccac 480agagatccgt ccacaaaagc ggaaaaaggg gccagccccc aaaatgctgg ggaacgagct 540atgcagcgtg tgtggggaca aggcctcggg cttccactac aatgttctga gctgcgaggg 600ctgcaaggga ttcttccgcc gcagcgtcat caagggagcg cactacatct gccacagtgg 660cggccactgc cccatggaca cctacatgcg tcgcaagtgc caggagtgtc ggcttcgcaa 720atgccgtcag gctggcatgc gggaggagtg tgtcctgtca gaagaacaga tccgcctgaa 780gaaactgaag cggcaagagg aggaacaggc tcatgccaca tccttgcccc ccagggcttc 840ctcacccccc caaatcctgc cccagctcag cccggaacaa ctgggcatga tcgagaagct 900cgtcgctgcc cagcaacagt gtaaccggcg ctccttttct gaccggcttc gagtcacgcc 960ttggcccatg gcaccagatc cccatagccg ggaggcccgt cagcagcgct ttgcccactt 1020cactgagctg gccatcgtct ctgtgcagga gatagttgac tttgctaaac agctacccgg 1080cttcctgcag ctcagccggg aggaccagat tgccctgctg aagacctctg cgatcgaggt 1140gatgcttctg gagacatctc ggaggtacaa ccctgggagt gagagtatca ccttcctcaa 1200ggatttcagt tataaccggg aagactttgc caaagcaggg ctgcaagtgg aattcatcaa 1260ccccatcttc gagttctcca gggccatgaa tgagctgcaa ctcaatgatg ccgagtttgc 1320cttgctcatt gctatcagca tcttctctgc agaccggccc aacgtgcagg accagctcca 1380ggtagagagg ctgcagcaca catatgtgga agccctgcat gcctacgtct ccatccacca 1440tccccatgac cgactgatgt tcccacggat gctaatgaaa ctggtgagcc tccggaccct 1500gagcagcgtc cactcagagc aagtgtttgc actgcgtctg caggacaaaa agctcccacc 1560gctgctctct gagatctggg atgtgcacga atgactgttc tgtccccata ttttctgttt 1620tcttggccgg atggctgagg cctggtggct gcctcctaga agtggaacag actgagaagg 1680gcaaacattc ctgggagctg ggcaaggaga tcctcccgtg gcattaaaag agagtcaaag 1740ggttgcgagt tttgtggcta ctgagcagtg gagccctcgc taacactgtg ctgtgtctga 1800agatcatgct gaccccacaa acggatgggc ctgggggcca ctttgcacag ggttctccag 1860agccctgccc atcctgcctc caccacttcc tgtttttccc acagggcccc aagaaaaatt 1920ctccactgtc aaaaaaaaa 1939632663DNAHomo sapiens 63tgcagctggg agcgcacaga cggctgcccc gcctgagcga ggcgggcgcc gccgcgatgc 60tgcgaggcgg acggcgcggg cagcttggct ggcacagctg ggctgcgggg ccgggcagcc 120tgctggcttg gctgatactg gcatctgcgg gcgccgcacc ctgccccgat gcctgctgcc 180cccacggctc ctcgggactg cgatgcaccc gggatggggc cctggatagc ctccaccacc 240tgcccggcgc agagaacctg actgagctct acatcgagaa ccagcagcat ctgcagcatc 300tggagctccg tgatctgagg ggcctggggg agctgagaaa cctcaccatc gtgaagagtg 360gtctccgttt cgtggcgcca gatgccttcc atttcactcc tcggctcagt cgcctgaatc 420tctccttcaa cgctctggag tctctctcct ggaaaactgt gcagggcctc tccttacagg 480aactggtcct gtcggggaac cctctgcact gttcttgtgc cctgcgctgg ctacagcgct 540gggaggagga gggactgggc ggagtgcctg aacagaagct gcagtgtcat gggcaagggc 600ccctggccca catgcccaat gccagctgtg gtgtgcccac gctgaaggtc caggtgccca 660atgcctcggt ggatgtgggg gacgacgtgc tgctgcggtg ccaggtggag gggcggggcc 720tggagcaggc cggctggatc ctcacagagc tggagcagtc agccacggtg atgaaatctg 780ggggtctgcc atccctgggg ctgaccctgg ccaatgtcac cagtgacctc aacaggaaga 840acgtgacgtg ctgggcagag aacgatgtgg gccgggcaga ggtctctgtt caggtcaacg 900tctccttccc ggccagtgtg cagctgcaca cggcggtgga gatgcaccac tggtgcatcc 960ccttctctgt ggatgggcag ccggcaccgt ctctgcgctg gctcttcaat ggctccgtgc 1020tcaatgagac cagcttcatc ttcactgagt tcctggagcc ggcagccaat gagaccgtgc 1080ggcacgggtg tctgcgcctc aaccagccca cccacgtcaa caacggcaac tacacgctgc 1140tggctgccaa ccccttcggc caggcctccg cctccatcat ggctgccttc atggacaacc 1200ctttcgagtt caaccccgag gaccccatcc ctgtctcctt ctcgccggtg gacactaaca 1260gcacatctgg agacccggtg gagaagaagg acgaaacacc ttttggggtc tcggtggctg 1320tgggcctggc cgtctttgcc tgcctcttcc tttctacgct gctccttgtg ctcaacaaat 1380gtggacggag aaacaagttt gggatcaacc gcccggctgt gctggctcca gaggatgggc 1440tggccatgtc cctgcatttc atgacattgg gtggcagctc cctgtccccc accgagggca 1500aaggctctgg gctccaaggc cacatcatcg agaacccaca atacttcagt gatgcctgtg 1560ttcaccacat caagcgccgg gacatcgtgc tcaagtggga gctgggggag ggcgcctttg 1620ggaaggtctt ccttgctgag tgccacaacc tcctgcctga gcaggacaag atgctggtgg 1680ctgtcaaggc actgaaggag gcgtccgaga gtgctcggca ggacttccag cgtgaggctg 1740agctgctcac catgctgcag caccagcaca tcgtgcgctt cttcggcgtc tgcaccgagg 1800gccgccccct gctcatggtc tttgagtata tgcggcacgg ggacctcaac cgcttcctcc 1860gatcccatgg acctgatgcc aagctgctgg ctggtgggga ggatgtggct ccaggccccc 1920tgggtctggg gcagctgctg gccgtggcta gccaggtcgc tgcggggatg gtgtacctgg 1980cgggtctgca ttttgtgcac cgggacctgg ccacacgcaa ctgtctagtg ggccagggac 2040tggtggtcaa gattggtgat tttggcatga gcagggatat ctacagcacc gactattacc 2100gtgtgggagg ccgcaccatg ctgcccattc gctggatgcc gcccgagagc atcctgtacc 2160gtaagttcac caccgagagc gacgtgtgga gcttcggcgt ggtgctctgg gagatcttca 2220cctacggcaa gcagccctgg taccagctct ccaacacgga ggcaatcgac tgcatcacgc 2280agggacgtga gttggagcgg ccacgtgcct gcccaccaga ggtctacgcc atcatgcggg 2340gctgctggca gcgggagccc cagcaacgcc acagcatcaa ggatgtgcac gcccggctgc 2400aagccctggc ccaggcacct cctgtctacc tggatgtcct gggctagggg gccggcccag 2460gggctgggag tggttagccg gaatactggg gcctgccctc agcatccccc atagctccca 2520gcagccccag ggtgatctca aagtatctaa ttcaccctca gcatgtggga agggacaggt 2580gggggctggg agtagaggat gttcctgctt ctctaggcaa ggtcccgtca tagcaattat 2640atttattatc ccttgaaaaa aaa 2663643961DNAHomo sapiens 64gtgtgtgtga gtgcgagagt gtgtaagcca gtgtgtgtgc cgtccccctg ctggggacag 60cagctgggtc cagcagagag ctggctgggg gcttgacagg agtttatcct aactgatgct 120gggtgggcgc aggccctgag atgggcgtca gggagagggg acgccagaca cacggcctga 180gcagggtgag gagcagctgc cagccccggc aggcccaggc cctgtctggg tgcacaggac 240agagacacag caagatgccc agggagtgcc gcttcctggg ctagagacaa gcaccagcct 300gcagtggaga acgcaggacc ccgctgccca gaaggagcag ccacggcctg cggaggactg 360gcccagcaag gtcccaggtc ttccctctcc tcagcgccta agagagaggc ccagtgcggg 420tgaggagtcg cgaggaagag gcggaaggcg ccggaaggca ccatgttccg caagaaaaag 480aagaaacgcc ctgagatctc agcgccacag aacttccagc accgtgtcca cacctccttc 540gaccccaaag aaggcaagtt tgtgggcctc cccccacaat ggcagaacat cctggacaca 600ctgcggcgcc ccaagcccgt ggtggaccct tcgcgaatca cacgggtgca gctccagccc 660atgaagacag tggtgcgggg cagcgcgatg cctgtggatg gctacatctc ggggctgctc 720aacgacatcc agaagttgtc agtcatcagc tccaacaccc tgcgtggccg cagccccacc 780agccggcggc gggcacagtc cctggggctg ctgggggatg agcactgggc caccgaccca 840gacatgtacc tccagagccc ccagtctgag cgcactgacc cccacggcct ctacctcagc 900tgcaacgggg gcacaccagc aggccacaag cagatgccgt ggcccgagcc acagagccca 960cgggtcctgc ccaatgggct ggctgcaaag gcacagtccc tgggccccgc cgagtttcag 1020ggtgcctcgc agcgctgtct gcagctgggt gcctgcctgc agagctcccc accaggagcc 1080tcgcccccca cgggcaccaa taggcatgga atgaaggctg ccaagcatgg ctctgaggag 1140gcccggccac agtcctgcct ggtgggctca gccacaggca ggccaggtgg ggaaggcagc 1200cctagcccta agacccggga gagcagcctg aagcgcaggc tattccgaag catgttcctg 1260tccactgctg ccacagcccc tccaagcagc agcaagccag gccctccacc acagagcaag 1320cccaactcct ctttccgacc gccgcagaaa gacaaccccc caagcctggt ggccaaggcc 1380cagtccttgc cctcggacca gccggtgggg accttcagcc ctctgaccac ttcggatacc 1440agcagccccc agaagtccct ccgcacagcc ccggccacag gccagcttcc aggccggtct 1500tccccagcgg gatccccccg cacctggcac gcccagatca gcaccagcaa cctgtacctg 1560ccccaggacc ccacggttgc caagggtgcc ctggctggtg aggacacagg tgttgtgaca 1620catgagcagt tcaaggctgc gctcaggatg gtggtggacc agggtgaccc ccggctgctg 1680ctggacagct acgtgaagat tggcgagggc tccaccggca tcgtctgctt ggcccgggag 1740aagcactcgg gccgccaggt ggccgtcaag atgatggacc tcaggaagca gcagcgcagg 1800gagctgctct tcaacgaggt ggtgatcatg cgggactacc agcacttcaa cgtggtggag 1860atgtacaaga gctacctggt gggcgaggag ctgtgggtgc tcatggagtt cctgcaggga 1920ggagccctca cagacatcgt ctcccaagtc aggctgaatg aggagcagat tgccactgtg 1980tgtgaggctg tgctgcaggc cctggcctac ctgcatgctc agggtgtcat ccaccgggac 2040atcaagagtg actccatcct gctgaccctc gatggcaggg tgaagctctc ggacttcgga 2100ttctgtgctc agatcagcaa agacgtccct aagaggaagt ccctggtggg aaccccctac 2160tggatggctc ctgaagtgat ctccaggtct ttgtatgcca ctgaggtgga tatctggtct 2220ctgggcatca tggtgattga gatggtagat ggggagccac cgtacttcag tgactcccca 2280gtgcaagcca tgaagaggct ccgggacagc cccccaccca agctgaaaaa ctctcacaag 2340gtctccccag tgctgcgaga cttcctggag cggatgctgg tgcgggaccc ccaagagaga 2400gccacagccc aggagctcct agaccacccc ttcctgctgc agacagggct acctgagtgc 2460ctggtgcccc tgatccagct ctaccgaaag cagacctcca cctgctgagc ccaccccaag 2520tatgcctgcc acctacgccc acaggcaggg cacactgggc agccagcctg ccggcaggac 2580ttgcctgcct cctcctctca gtattctctc caaagattga aatgtgaagc cccagcccca 2640ccctctgccc ttcagcctac tgggccaggc cggacctgcc ccctcagtgt ctctccctcc 2700cgagtcccca gatggagacc cctttctaca ggatgacccc ttgatatttg cacagggata 2760tttctaagaa acgcagaggc cagcgttcct ggcctctgca gccaacacag tagaaaaggc 2820tgctgtggtt ttttaaaggc agttgtccac tagtgtccta ggccactgca gagggcagac 2880tgctggtctc cacagatacc tgctgttctc agctccagct tcaaacctcg agtctcgaga 2940gggccacggg gtggttttta tgaccggaat cccgcttcct

ccctcacgtc tgatgtcctg 3000aaggtgcagt cccacctgta cagcccctcc ccgcccagaa ctgtgaatgg cctgctccag 3060gccatggctg ggggcaggga gtgaggggac aatttctgag tgaaagagaa agaatggggt 3120cggtggtgaa ggtgctctca ctttacagaa tggagagaac atcgtgtgtg tgtgtgtgtg 3180tgtgtgtgtg tgtgtgtgtg tgtaagggga ggaaagccac cttgacagcc caggtccctc 3240caggtcaccc acagccagtt tcaggaaggc tgcccctctc tcccactaag ttctggcctg 3300aagggacctg ctttcttggc ctggcttcca cctctccact cctgtgtcta cctggccagt 3360ggagtggtcc atgctaagtc taacactcct gggagctcag gaggcttctg agcttctcct 3420gtactgtgca tcgtgagggc cagagacagg aatgtaagga ttggcaactg tgttaccttt 3480caagtttatc tcaataacca ggtcatcagg gacccattgt tctcttcaga accctatctg 3540ggagagaagg cgaaccacct ccgggtttcc atcatgtcaa ggtcacaggc atccatgtgt 3600gcaaaccatc tgccccagct gcctccacag actgctgtct ccttgtcctc ctcggccctg 3660ccccacttca gggctgctgt gagatggaat tccaggaaag aacttcaggt gtctggaccc 3720tttctatcta gataatattt ttagattctt ctgctcccta gtgacctacc tgggggcaaa 3780gaaattgcaa ggactttttt ttaagggtca gagttttcaa aacaaaagca tcttccctag 3840aaatttttgt gaattgtttg cacttgtgcc tgttttaaat taaattgagt gttcaaagcc 3900aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 3960a 3961651899DNAHomo sapiens 65agcgcgcgac tttttgaaag ccaggagggt tcgaattgca acggcagctg ccgggcgtat 60gtgttggtgc tagaggcagc tgcagggtct cgctgggggc cgctcgggac caattttgaa 120gaggtacttg gccacgactt attttcacct ccgacctttc cttccaggcg gtgagactct 180ggactgagag tggctttcac aatggaaggg atcagtaatt tcaagacacc aagcaaatta 240tcagaaaaaa agaaatctgt attatgttca actccaacta taaatatccc ggcctctccg 300tttatgcaga agcttggctt tggtactggg gtaaatgtgt acctaatgaa aagatctcca 360agaggtttgt ctcattctcc ttgggctgta aaaaagatta atcctatatg taatgatcat 420tatcgaagtg tgtatcaaaa gagactaatg gatgaagcta agattttgaa aagccttcat 480catccaaaca ttgttggtta tcgtgctttt actgaagcca atgatggcag tctgtgtctt 540gctatggaat atggaggtga aaagtctcta aatgacttaa tagaagaacg atataaagcc 600agccaagatc cttttccagc agccataatt ttaaaagttg ctttgaatat ggcaagaggg 660ttaaagtatc tgcaccaaga aaagaaactg cttcatggag acataaagtc ttcaaatgtt 720gtaattaaag gcgattttga aacaattaaa atctgtgatg taggagtctc tctaccactg 780gatgaaaata tgactgtgac tgaccctgag gcttgttaca ttggcacaga gccatggaaa 840cccaaagaag ctgtggagga gaatggtgtt attactgaca aggcagacat atttgccttt 900ggccttactt tgtgggaaat gatgacttta tcgattccac acattaatct ttcaaatgat 960gatgatgatg aagataaaac ttttgatgaa agtgattttg atgatgaagc atactatgca 1020gcgttgggaa ctaggccacc tattaatatg gaagaactgg atgaatcata ccagaaagta 1080attgaactct tctctgtatg cactaatgaa gaccctaaag atcgtccttc tgctgcacac 1140attgttgaag ctctggaaac agatgtctag tgatcatctc agctgaagtg tggcttgcgt 1200aaataactgt ttattccaaa atatttacat agttactatc agtagttatt agactctaaa 1260attggcatat ttgaggacca tagtttcttg ttaacatatg gataactatt tctaatatga 1320aatatgctta tattggctat aagcacttgg aattgtactg ggttttctgt aaagttttag 1380aaactagcta cataagtact ttgatactgc tcatgctgac ttaaaacact agcagtaaaa 1440cgctgtaaac tgtaacatta aattgaatga ccattacttt tattaatgat ctttcttaaa 1500tattctatat tttaatggat ctactgacat tagcactttg tacagtacaa aataaagtct 1560acatttgttt aaaacactga accttttgct gatgtgttta tcaaatgata actggaagct 1620gaggagaata tgcctcaaaa agagtagctc cttggatact tcagactctg gttacagatt 1680gtcttgatct cttggatctc ctcagatctt tggtttttgc tttaatttat taaatgtatt 1740ttccatactg agtttaaaat ttattaattt gtaccttaag catttcccag ctgtgtaaaa 1800acaataaaac tcaaatagga tgataaagaa taaaggacac tttgggtacc agaaaaaaaa 1860aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaa 1899661025DNAHomo sapiens 66cggggtggga ttccaaccca gaagcgggca tttggagccc tcatgcttca ccctagctcc 60ctgaaacaag cacggaggat ggctctgagc agcgaggaaa gtgctggaag caagcaggcc 120gagcgcgtcc ctggctgggg acgttaatca ttaccggagg gcggcccgag cgcggccccg 180ccccgggacg gcagcctgcg cgcccggccg ccgcctgccc tctccgctgg ccacctgctg 240ccgcccgcgc catggctggc aaagcacaca ggctgagcgc tgaggagagg gaccagctgc 300tgccaaacct gagggctgtg gggtggaatg agctggaagg ccgtgatgcc atcttcaagc 360agtttcattt caaagacttc aacagggcct ttgggttcat gacaagagtg gccctgcagg 420ctgagaaact ggaccaccat cctgaatggt ttaacgtgta caacaaggtc cacatcacgc 480tgagcaccca tgagtgtgcc ggcctttcag aacgggacat aaacctggcc agcttcatcg 540aacaagtagc agtgtccatg acatagaccc tgcccttcct ctttgaattc ttccggggga 600aggggtgact gaactgggag tccagggagg gagctgagga gcccttaccc tcccaccact 660cccctcccaa gacccagccg ccgccgttga gggctgagtc cttgctgtgg gatgtgccag 720tgtccccacc aacaccagga atttagacct tttccctgca ccactctctt catcctgggg 780gctctgttac actaatttga ataaactctc ccctttcttt gcaacttccc agcaacaata 840atgattttct tgccaggccg tctcttgctc cctaattcat ttcccaggaa gctgtgatac 900agggtgaaat aaagtcttgt cttagaaacc aggaccctaa accccacact atgtaataga 960aacacatgtg tttttatgtc tcaaataaaa ctattatatc acttggaaaa aaaaaaaaaa 1020aaaaa 1025674576DNAHomo sapiens 67gatccccgcc cctgctgccc gccacgtccc tcacgtacca ctcggcagag gcgcggggaa 60acctggcgta ctggctgtgg cttctctagc gggactcggc atgaggctgg cgcggctgct 120tcgcggagcc gccttggccg gcccgggccc ggggctgcgc gccgccggct tcagccgcag 180cttcagctcg gactcgggct ccagcccggc gtccgagcgc ggcgttccgg gccaggtgga 240cttctacgcg cgcttctcgc cgtccccgct ctccatgaag cagttcctgg acttcggatc 300agtgaatgct tgtgaaaaga cctcatttat gtttctgcgg caagagttgc ctgtcagact 360ggcaaatata atgaaagaaa taagtctcct tccagataat cttctcagga caccatccgt 420tcaattggta caaagctggt atatccagag tcttcaggag cttcttgatt ttaaggacaa 480aagtgctgag gatgctaaag ctatttatga ctttacagat actgtgatac ggatcagaaa 540ccgacacaat gatgtcattc ccacaatggc ccagggtgtg attgaataca aggagagctt 600tggggtggat cctgtcacca gccagaatgt tcagtacttt ttggatcgat tctacatgag 660tcgcatttca attagaatgt tactcaatca gcactcttta ttgtttggtg gaaaaggcaa 720aggaagtcca tctcatcgaa aacacattgg aagcataaat ccaaactgca atgtacttga 780agttattaaa gatggctatg aaaatgctag gcgtctgtgt gatttgtatt atattaactc 840tcccgaacta gaacttgaag aactaaatgc aaaatcacca ggacagccaa tacaagtggt 900ttatgtacca tcccatctct atcacatggt gtttgaactt ttcaagaatg caatgagagc 960cactatggaa caccatgcca acagaggtgt ttacccccct attcaagttc atgtcacgct 1020gggtaatgag gatttgactg tgaagatgag tgaccgagga ggtggcgttc ctttgaggaa 1080aattgacaga cttttcaact acatgtattc aactgcacca agacctcgtg ttgagacctc 1140ccgcgcagtg cctctggctg gttttggtta tggattgccc atatcacgtc tttacgcaca 1200atacttccaa ggagacctga agctgtattc cctagagggt tacgggacag atgcagttat 1260ctacattaag gctctgtcaa cagactcaat agaaagactc ccagtgtata acaaagctgc 1320ctggaagcat tacaacacca accacgaggc tgatgactgg tgcgtcccca gcagagaacc 1380caaagacatg acgacgttcc gcagtgccta gacacacttg ggacatcgga aaatccaaat 1440gtggcttttg tattaaattt ggaaggtatg gtgttcagaa ctatattata ccaagtactt 1500tatttatcgt tttcacaaaa ctatttgagt agaataaatg gaaactgaat tccatttgtg 1560cccgttaaac ctcctaaagg atgaaattgc acctatttta cacttatatt ttcacagtta 1620attgaacata tttttaaaca actgtagttt tgggcaactt ttcactttgt ggtagacttc 1680agaagtgtgg aaatcttcgg gtttctatag gaaactagtt tttttttttt aagaaatact 1740ttcatttatg tttgctagaa acattttcta aatgatagtg attagctggt tagccatctt 1800cctgttattt ggaggagttc tgccatcttt tattcggtag tgacagctgt aatatggtct 1860tcatgtttat cagtgacttg actacaagta aagcagaaaa cagttggcct gtaatcacag 1920aaccagccac ccttcggcgt ctacatgcat tgtcttagct ctgaggttaa tttaccattt 1980ttaaatttta ttgtaaagaa gtgtaatgac tagctctctg tggatctatg ccaaaatcat 2040gggccatctt ttctaagtgt acttctgatt aatgcaaggg gaaattttta tactgaaaac 2100aaacaaacaa actagcagct actaaaatag agaagaaatt gagggcaaag taatatgtct 2160ccaaaactga actgattgct tgttgagatt acctagaaag cttttggaaa aaaatagagc 2220ttttctgcat cctactccag atacactgaa tcggaatccc tagggctaga gcctagaaat 2280ctcacttttt aaaatgcttc caaggtaagt ctgatgccta ccctaggttg ggaaccactc 2340tttcaaagta aacagtgatg acacagcatt tgctaaagta acatctgtag gttttggttt 2400ccacctattt aaagtcagat ttatagactc gaggagacag aaactgaatc ccacacctgg 2460tgcaattaga agcataatta gaagcagaag aacaaaatgc cacgtaacca aagcatcaga 2520gccatcattg cacgtgtctt tttttctttt ttcttttttt tttttcaaga cagggtctcg 2580ctcttttgcc caggatggag tacagtggca tggtcaaggc tcactgcagc ttcaatcttc 2640tgggctcaag taatccttcc acctcagcct cccatatagc tggaactaca gttgtgcact 2700accacaccca gctaattttt tgatttcttg tggagatgag gtctcagtat gttcccaggc 2760tagtgttgaa ctcctgagct caagaaatcc tcctgcctga gtctctgaaa gtgctgggat 2820tacaggcgtg agccaccaca catggcctat tgcacaagtc ttgacaaaca acatatattt 2880tctaaaacta tccagatttc attatcaggg aaaagtttgc ttaggtttat tacagcagtc 2940cttggcattt gtatggtaat ttgtacttta caaatacttt gatatattat aactctattg 3000gtctttgaaa caaagcgata cagtgtaggt ggtatcattc tctttctcac tcagtgtggc 3060ccagagttgc tcagaattgg agcagagcct gagacgtatc tgcagatcct gtcatcagct 3120ggcaagtcca ggagactgtg tcatttagag actgtgttgt tagttatccc tcaacatctt 3180ctaaggtggc aggaaataat attggaaata acattttaaa gtaaaaattt taaagtttaa 3240agaagagttt tgccacttaa acaggggagc tttgtctgga aaatacactg agttgaaaca 3300cttcatcctt ggaaggatta tataagatga acagttgtga taaatgtgta gattagaggg 3360atgtgaatgg gcagttagtc cagtgccctc atttaagagg ccaagatcct gattcagagg 3420aggcatcctt tgcccagagc tgcttagcta atctgaccaa atgttgggaa aaatgtctca 3480cctaacccac tattccttaa ttatggattt tgtgaaaaac aatagaacat gttaatgagt 3540aatttatatt agttcgatgt attacaattt tttagcttta aattacagtt ttcttataat 3600gttgaaatgt tttagaatcc tttgaatcta agtatttgtt tcctaaatga aacatttgta 3660caacatttga tgtttttact tatgaaatat tctcctcccc caagaaaatt taaacttttt 3720ctctctattt aaaagctaag aaatgtttta aaggaaaaat gaaattatct tcctttagct 3780tatttttaag gtaaaacagc tttttactct gttattgtgg taatggacag aatattacat 3840acaaaaatat tctgggagag ctttttccta gttggtttta aatcattgtg ccacctgaaa 3900ggtttttaga ttttatagga gctaatttgt ccaccagcat taatgtaaca cagtgtagtt 3960atgaaaatat attgaaggac aggaagtgga cacgaagtga tttttgtaac ctgagcagtt 4020aatgaatgtg ccaacatttt ctaggaaggg acagcaagaa tattctgctc tgtagttaaa 4080atactggctg gcttttgatg tcttcatgct taattgtgat cactttcttg cactgtgatg 4140tttttacgtg aatatgttga agtagaagtc taccatatta ttttataaaa tgttttctgt 4200atggcaataa actgaaaaca tggatcaacc cttcttttga aaataaactg agtcaattta 4260gccttttaaa aatatagtca tctcttttaa atagaatcct cttccaccat caaggctcaa 4320cattttgtaa gcatccaaaa aattggtaat tagggggctt gcactaaatt tcactatctt 4380cagtagagag gaactgtttg gaacttagat ttccaatgtg tatattctaa tggagaaagc 4440aagaggtaga gtttgtatgt ttgacttacc ttagattttt attttccata catactgcaa 4500atgattgact tgttgcataa atgaagatct tctgttgtgt gcttttcaaa cactgtaaat 4560aaatttgaaa tttgaa 4576682312DNAHomo sapiens 68agacagcgtg gggtggggag ggtcctcggg gtccttggca gggcacgtgc gggaggaagt 60ggagctccct gtacgcgcgg ccctagtcgg ctcctcaacg tggagcgatg ggaggccttg 120agaagaagaa gtatgaacga ggctcggcca ccaactacat cacccggaac aaagcccgga 180agaagctcca gctgagcttg gctgacttta ggcggctgtg cattctgaag ggcatttatc 240cccatgaacc caaacacaag aagaaggtta acaagggttc tacagcagcc cgaacgtttt 300accttatcaa agacatcagg tttctcctcc acgaacccat tgtcaacaag ttccgtgaat 360acaaggtgtt cgtccggaag ctccggaagg cttatgggaa gagcgagtgg aacactgtag 420agcgtttaaa ggacaataag cccaactaca aactcgacca catcatcaag gaacggtatc 480ccacgttcat cgatgccctg cgggacctgg acgatgccct ctccatgtgc ttcctgtttt 540ccaccttccc gcggactggc aagtgccacg tgcagaccat tcagctgtgc cgccggctca 600ctgtggagtt catgcactac attatcgctg cccgtgccct gcgcaaggtc ttcctgtcca 660tcaaaggcat ttactaccag gccgaggtac tggggcagcc catcgtgtgg atcactccct 720atgccttctc ccatgaccac ccgacagacg tggactacag ggtcatggcc accttcaccg 780agttctacac cacgctgctg ggctttgtca acttccgcct ttaccagttg ctcaacctcc 840actatccccc gaagctcgag ggtcaggccc aagcagaggc aaaggccggt gagggcacct 900acgcgttgga ctccgagagt tgtatggaga aactggcagc cctcagtgcc agcctggccc 960gcgtggtggt gcctgccaca gaggaggagg ccgaggtgga tgagtttccc accgatgggg 1020agatgtcagc gcaggaggaa gaccgcagga aggagctgga ggcgcaggag aagcacaaga 1080agctttttga gggcctgaag ttcttcctga accgagaggt gccccgtgag gccctggcct 1140tcatcatcag gagttttggt ggggaagtgt cctgggacaa atctttgtgc attggggcca 1200cctatgacgt cacagactcc cgcatcaccc atcagattgt cgaccggcct gggcagcaga 1260cctcagtcat tggcaggtgc tacgtgcagc cccagtgggt gtttgactca gtgaacgcca 1320ggctccttct ccccgtggca gagtacttct ctggggtgca gctgccccca cacctttcac 1380cctttgtgac cgagaaggaa ggagattacg ttccacctga gaagctgaag ctgctggctc 1440tgcagcgggg agaggaccca ggaaacctga atgagtcaga agaggaggag gaagaggacg 1500acaacaacga aggtgatggt gatgaagagg gagaaaatga ggaggaggag gaagatgcag 1560aggctggttc agaaaaggag gaagaggccc ggctggcagc cctggaagag cagaggatgg 1620aggggaagaa gcccagggtg atggcaggca ccttgaagct ggaggataag cagcggctgg 1680cccaggagga ggagagtgag gccaagcgcc tggccattat gatgatgaag aagcgggaga 1740agtacctgta ccagaagatc atgtttggca agaggcgaaa aatccgagag gccaacaagc 1800tggcggagaa gcggaaagcc cacgatgagg cggtgaggtc tgagaagaag gccaagaagg 1860caaggccgga gtgagtgcct gcggcccctc acagggctga ggccagcccc tagcagctgg 1920atgtggcaga ggcaggccag aggacctaag tgtgatggac cagagtcact tctcctcctc 1980ctttctccag ccagccctga cccctcatgc tctctggctg ggccagtggg cagccctcgc 2040ttcccttgga tggagctgcc ctgctggtgc ctggtcagag aagaggcctc tgtgcccagc 2100ctgattctct gctcccagga gccagtgaca tgaggtgcag aggcccaccc agccccctac 2160ctactgcccc cattcatcct ggctttccac agccccctcc cacacagttg gacccgtgat 2220tctcagggtg ctgtgatggg gtgagggtag ggggagcatt tgttattaaa tgactggact 2280tttgtgccaa ttgcaaaaaa aaaaaaaaaa aa 2312694123DNAHomo sapiens 69agattactat ggaatcggta gggtcctgac cgctggggaa gcaggaaagc gtatcctggg 60aagaaaggct tggcttggac tccggagaag aatactacat cgagacctgc tggggaattt 120tattttattt tattattttt ttggtcttgg ttgtactgag ggaggaagaa gaggttgtgt 180ggcccggtcg aacttgtggc agcctgaagg ccccctcagg cggcgccgcg ggcagccccg 240cagccggggc ctggtgcagc ctccgcggcc gctgtcaggg aagcgcaggc ggccaatgga 300acccgggagc ggtcgctgct gctgaggcgg cagtgtcggc agtccaaccg cgactgcccg 360caccccctcc gcgggggtcc cccagaggat caactaaacc ttgaactaag aagaaaaatg 420tgttgtgagc agggggagcc tcagctgcct caggccgttc aggacagaag ggtgtttctg 480aaggccggag caagttttga agaagtccct atcagattac acttggttga ctactccgga 540gcagccacta agagggatga acaggcctgc gtggaaattg aatgagattc ttggaagctc 600gaagtctggc tgtggccatg ggagatacag tagtggagcc tgcccccttg aagccaactt 660ctgagcccac ttctggccca ccagggaata atggggggtc cctgctaagt gtcatcacgg 720agggggtcgg ggaactatca gtgattgacc ctgaggtggc ccagaaggcc tgccaggagg 780tgttggagaa agtcaagctt ttgcatggag gcgtggcagt ctctagcaga ggcaccccac 840tggagttggt caatggggat ggtgtggaca gtgagatccg ttgcctagat gatccacctg 900cccagatcag ggaggaggaa gatgagatgg gggccgctgt ggcctcaggc acagccaaag 960gagcaagaag acggcggcag aacaactcag ctaaacagtc ttggctgctg aggctgtttg 1020agtcaaaact gtttgacatc tccatggcca tttcatacct gtataactcc aaggagcctg 1080gagtacaagc ctacattggc aaccggctct tctgctttcg caacgaggac gtggacttct 1140atctgcccca gttgcttaac atgtacatcc acatggatga ggacgtgggt gatgccatta 1200agccctacat agtccaccgt tgccgccaga gcattaactt ttccctccag tgtgccctgt 1260tgcttggggc ctattcttca gacatgcaca tttccactca acgacactcc cgtgggacca 1320agctacggaa gctgatcctc tcagatgagc taaagccagc tcacaggaag agggagctgc 1380cctccttgag cccggcccct gacacagggc tgtctccctc caaaaggact caccagcgct 1440ctaagtcaga tgccactgcc agcataagtc tcagcagcaa cctgaaacga acagccagca 1500accctaaagt ggagaatgag gatgaggagc tctcctccag caccgagagt attgataatt 1560cattcagttc ccctgttcga ctggctcctg agagagaatt catcaagtcc ctgatggcga 1620tcggcaagcg gctggccacg ctccccacca aagagcagaa aacacagagg ctgatctcag 1680agctctccct gctcaaccat aagctccctg cccgagtctg gctgcccact gctggctttg 1740accaccacgt ggtccgtgta ccccacacac aggctgttgt cctcaactcc aaggacaagg 1800ctccctacct gatttatgtg gaagtccttg aatgtgaaaa ctttgacacc accagtgtcc 1860ctgcccggat ccccgagaac cgaattcgga gtacgaggtc cgtagaaaac ttgcccgaat 1920gtggtattac ccatgagcag cgagctggca gcttcagcac tgtgcccaac tatgacaacg 1980atgatgaggc ctggtcggtg gatgacatag gcgagctgca agtggagctc cccgaagtgc 2040ataccaacag ctgtgacaac atctcccagt tctctgtgga cagcatcacc agccaggaga 2100gcaaggagcc tgtgttcatt gcagcagggg acatccgccg gcgcctttcg gaacagctgg 2160ctcatacccc gacagccttc aaacgagacc cagaagatcc ttctgcagtt gctctcaaag 2220agccctggca ggagaaagta cggcggatca gagagggctc cccctacggc catctcccca 2280attggcggct cctgtcagtc attgtcaagt gtggggatga ccttcggcaa gagcttctgg 2340cctttcaggt gttgaagcaa ctgcagtcca tttgggaaca ggagcgagtg cccctttgga 2400tcaagccata caagattctt gtgatttcgg ctgatagtgg catgattgaa ccagtggtca 2460atgctgtgtc catccatcag gtgaagaaac agtcacagct ctccttgctc gattacttcc 2520tacaggagca cggcagttac accactgagg cattcctcag tgcacagcgc aattttgtgc 2580aaagttgtgc tgggtactgc ttggtctgct acctgctgca agtcaaggac agacacaatg 2640ggaatatcct tttggacgca gaaggccaca tcatccacat cgactttggc ttcatcctct 2700ccagctcacc ccgaaatctg ggctttgaga cgtcagcctt taagctgacc acagagtttg 2760tggatgtgat gggcggcctg gatggcgaca tgttcaacta ctataagatg ctgatgctgc 2820aagggctgat tgccgctcgg aaacacatgg acaaggtggt gcagatcgtg gagatcatgc 2880agcaaggttc tcagcttcct tgcttccatg gctccagcac cattcgaaac ctcaaagaga 2940ggttccacat gagcatgact gaggagcagc tgcagctgct ggtggagcag atggtggatg 3000gcagtatgcg gtctatcacc accaaactct atgacggctt ccagtacctc accaacggca 3060tcatgtgaca cgctcctcag cccaggagtg gtggggggtc cagggcaccc tccctagagg 3120gcccttgtct gagaaacccc aaaccaggaa accccaccta cccaaccatc cacccaaggg 3180aaatggaagg caagaaacac gaaggatcat gtggtaactg cgagagcttg ctgaggggtg 3240ggagagccag ctgtggggtc cagacttgtt ggggcttccc tgcccctcct ggtctgtgtc 3300agtattacca ccagactgac tccaggactc actgccctcc agaaaacaga ggtgacaaat 3360gtgagggaca ctggggcctt tcttctcctt gtaggggtct ctcagaggtt ctttccacag 3420gccatcctct tattccgttc tggggcccag gaagtgggga agagtaggtt ctcggtactt 3480aggacttgat cctgtggttg gccactggcc atgctgctgc ccagctctac ccctcccagg 3540gacctacccc tcccagggac cgacccctgg cccaagctcc ccttgctggc gggcgctgcg 3600tgggccctgc acttgctgag gttccccatc atgggcaagg aagggaattc ccacagccct 3660ccagtgtact gagggtactg gcctagccat gtggaattcc ctaccctgac tccttcccca 3720aacccaggga aaagagctct caatttttta tttttaattt ttgtttgaaa taaagtcctt 3780agttagccac ttgtgtcatt tccaggtttt ctgggggagt gcagggggag atgggtgatg 3840aggtatgaac ggatgcctca gtgtccaaga tacaaaaggc actacataga agtttgcttt 3900ttccctgcct gtcttggtca ctaccacctc ttccctgaga agggcgggcc ttccatgttc

3960tctcacccgc ttcaactcca cattgtccaa gtcacagaaa aagagaggcc tgaatggaga 4020ttcgaccaca aacagtttta atggtctggt tttctcccta gttccccaac tgtttgttag 4080tattattatt actacaagaa taaaggattc ctgagagcct gtc 4123703097DNAHomo sapiens 70acgcggcggc ctggccaggc gaggcgggag ccgagcaggc cggagcgggc cgcgcgccgg 60ggagggtcgc gccgcgcccg ccccctcccc gccacgcccg gggcgcacgc gcgctcctct 120ggccgcccct ccctccgcgc ggggacccct ggcgggcggc aggaggacat ggccagcgac 180gccgtgcaga gtgagcctcg cagctggtcc ctgctagagc agctgggcct ggccggggca 240gacctggcgg cccccggggt acagcagcag ctggagctgg agcgggagcg gctgcggcgg 300gaaatccgca aggagctgaa gctgaaggag ggtgctgaga acctgcggcg ggccaccact 360gacctgggcc gcagcctggg ccccgtagag ctgctgctgc ggggctcctc gcgccgcctc 420gacctgctgc accagcagct gcaggagctg cacgcccacg tggtgcttcc cgacccggcg 480gccacccacg atggccccca gtcccctggt gcgggtggcc ccacctgctc ggccaccaac 540ctgagccgcg tggcgggcct ggagaagcag ttggccattg agctgaaggt gaagcagggg 600gcggagaaca tgatccagac ctacagcaat ggcagcacca aggaccggaa gctgctgctg 660acagcccagc agatgttgca ggacagtaag accaagattg acatcatccg catgcaactc 720cgccgggcgc tgcaggccgg ccagctggag aaccaggcag ccccggatga cacccaaggg 780agtcctgacc tgggggctgt ggagctgcgc atcgaagagc tgcggcacca cttccgagtg 840gagcacgcgg tggccgaggg tgccaagaac gtactgcgcc tgctcagcgc tgccaaggcc 900ccggaccgca aggcagtcag cgaggcccag gagaaattga cagaatccaa ccagaagctg 960gggctgctgc gggaggctct ggagcggaga cttggggagc tgcccgccga ccaccccaag 1020gggcggctgc tgcgagaaga gctcgctgcg gcctcctccg ctgccttcag cacccgcctg 1080gccgggccct ttcccgccac gcactacagc accctgtgca agcccgcgcc gctcacaggg 1140accctggagg tacgagtggt gggctgcaga gacctcccag agaccatccc gtggaaccct 1200accccctcaa tggggggacc tgggacccca gacagccgcc cccccttcct gagccgccca 1260gcccggggcc tttacagccg aagcggaagc ctcagtggcc ggagcagcct caaagcagaa 1320gccgagaaca ccagtgaagt cagcactgtg cttaagctgg ataacacagt ggtggggcag 1380acgtcttgga agccatgtgg ccccaatgcc tgggaccaga gcttcactct ggagctggaa 1440agggcacggg aactggagtt ggctgtgttc tggcgggacc agcggggcct gtgtgccctc 1500aaattcctga agttggagga tttcttggac aatgagaggc atgaggtgca gctggacatg 1560gaaccccagg gctgcctggt ggctgaggtc accttccgca accctgtcat tgagaggatt 1620cctcggctcc gacggcagaa gaaaattttc tccaagcagc aagggaaggc gttccagcgt 1680gctaggcaga tgaacatcga tgtcgccacg tgggtgcggc tgctccggag gctcatcccc 1740aatgccacgg gcacaggcac ctttagccct ggggcttctc caggatccga ggcccggacc 1800acgggtgaca tatcggtgga gaagctgaac ctcggcactg actcggacag ctcacctcag 1860aagagctcgc gggatcctcc ttccagccca tcgagcctga gctcccccat ccaggaatcc 1920actgctcccg agctgccttc ggagacccag gagaccccag gccccgccct gtgcagccct 1980ctgaggaagt cacctctgac cctcgaagat ttcaagttcc tggcggtgct gggccggggt 2040cattttggga aggtgctcct ctccgaattc cggcccagtg gggagctgtt cgccatcaag 2100gctctgaaga aaggggacat tgtggcccga gacgaggtgg agagcctgat gtgtgagaag 2160cggatattgg cggcagtgac cagtgcggga caccccttcc tggtgaacct cttcggctgt 2220ttccagacac cggagcacgt gtgcttcgtg atggagtact cggccggtgg ggacctgatg 2280ctgcacatcc acagcgacgt gttctctgag ccccgtgcca tcttttattc cgcctgcgtg 2340gtgctgggcc tacagtttct tcacgaacac aagatcgtct acagggacct gaagttggac 2400aatttgctcc tggacaccga gggctacgtc aagatcgcag actttggcct ctgcaaggag 2460gggatgggct atggggaccg gaccagcaca ttctgtggga ccccggagtt cctggcccct 2520gaggtgctga cggacacgtc gtacacgcga gctgtggact ggtggggact gggtgtgctg 2580ctctacgaga tgctggttgg cgagtcccca ttcccagggg atgatgagga ggaggtcttc 2640gacagcatcg tcaacgacga ggttcgctac ccccgcttcc tgtcggccga agccatcggc 2700atcatgagaa ggctgcttcg gaggaaccca gagcggaggc tgggatctag cgagagagat 2760gcagaagatg tgaagaaaca gcccttcttc aggactctgg gctgggaagc cctgttggcc 2820cggcgcctgc caccgccctt tgtgcccacg ctgtccggcc gcaccgacgt cagcaacttc 2880gacgaggagt tcaccgggga ggcccccaca ctgagcccgc cccgcgacgc gcggcccctc 2940acagccgcgg agcaggcagc cttcctggac ttcgacttcg tggccggggg ctgctagccc 3000cctcccctgc ccctgcccct gcccctgccc gagagctctt agtttttaaa aaggcctttg 3060ggatttgccg gatccttgca aaaaaaaaaa aaaaaaa 3097715455DNAHomo sapiens 71gggagattcg ggaccatggc acctgtgcac ggcgacgact ctctgtcaga ttcagggagt 60tttgtatctt ctcgagcccg gcgagaaaaa aaatcaaaga aggggcgcca agaagcccta 120gaaagactga aaaaggctaa agctggtgag aagtataaat atgaagtcga ggacttcaca 180ggtgtttatg aagaagttga tgaagaacag tattcgaagc tggttcaggc acgccaggat 240gatgactgga ttgtggatga tgatggtatt ggctatgtgg aagatggccg agagattttt 300gatgatgacc ttgaagatga tgcccttgat gctgatgaga aaggaaaaga tggtaaagca 360cgcaataaag acaagaggaa tgtaaagaag ctcgcagtga caaaaccgaa caacattaag 420tcaatgttca ttgcttgtgc tggaaagaaa actgcagata aagctgtaga cttgtccaag 480gatggtctgc taggtgacat tctacaggat cttaacactg agacacctca aataactcca 540ccacctgtaa tgatactgaa gaagaaaaga tccattggag cttcaccgaa tcctttctct 600gtgcacaccg ccacggcagt tccttcagga aaaattgctt cccctgtctc cagaaaggag 660cctccattaa ctcctgttcc tcttaaacgt gctgaatttg ctggcgatga tgtacaggtc 720gagagtacag aagaagagca ggagtcaggg gcaatggagt ttgaagatgg tgactttgat 780gagcccatgg aagttgaaga ggtggacctg gagcctatgg ctgccaaggc ttgggacaaa 840gagagtgagc cagcagagga agtgaaacaa gaggcggatt ctgggaaagg gaccgtgtcc 900tacttaggaa gttttctccc ggatgtctct tgttgggaca ttgatcaaga aggtgatagc 960agtttctcag tgcaagaagt tcaagtggat tccagtcacc tcccattggt aaaaggggca 1020gatgaggaac aagtattcca cttttattgg ttggatgctt atgaggatca gtacaaccaa 1080ccaggtgtgg tatttctgtt tgggaaagtt tggattgaat cagccgagac ccatgtgagc 1140tgttgtgtca tggtgaaaaa tatcgagcga acgctttact tccttccccg tgaaatgaaa 1200attgatctaa atacggggaa agaaacagga actccaattt caatgaagga tgtttatgag 1260gaatttgatg agaaaatagc aacaaaatat aaaattatga agttcaagtc taagccagtg 1320gaaaagaact atgcttttga gatacctgat gttccagaaa aatctgagta cttggaagtt 1380aaatactcgg ctgaaatgcc acagcttcct caagatttga aaggagaaac tttttctcat 1440gtatttggga ccaacacatc tagcctggaa ctgttcttga tgaacagaaa gatcaaagga 1500ccttgttggc ttgaagtaaa aagtccacag ctcttgaatc agccagtcag ttggtgtaaa 1560gttgaggcaa tggctttgaa accagacctg gtgaatgtaa ttaaggatgt cagtccacca 1620ccgcttgtcg tgatggcttt cagcatgaag acaatgcaga atgcaaagaa ccatcaaaat 1680gagattattg ctatggcagc tttggtccat cacagttttg cattggataa agcagcccca 1740aagcctccct ttcagtcaca cttctgtgtt gtgtctaaac caaaggactg tatttttcca 1800tatgctttca aagaagtcat tgagaaaaag aatgtgaagg ttgaggttgc tgcaacagaa 1860agaacactgc taggtttttt ccttgcaaaa gttcacaaaa ttgatcctga tatcattgtg 1920ggtcataata tttatgggtt tgaactggaa gtactactgc agagaattaa tgtgtgcaaa 1980gctcctcact ggtccaagat aggtcgactg aagcgatcca acatgccaaa gcttgggggc 2040cggagtggat ttggtgaaag aaatgctacc tgtggtcgaa tgatctgtga tgtggaaatt 2100tcagcaaagg aattgattcg ttgtaaaagc taccatctgt ctgaacttgt tcagcagatt 2160ctaaaaactg aaagggttgt aatcccaatg gaaaatatac aaaatatgta cagtgaatct 2220tctcaactgt tatacctgtt ggaacacacc tggaaagatg ccaagttcat tttgcagatc 2280atgtgtgagc taaatgttct tccattagca ttgcagatca ctaacatcgc tgggaacatt 2340atgtccagga cgctgatggg tggacgatcc gagcgtaacg agttcttgtt gcttcatgca 2400ttttacgaaa acaactatat tgtgcctgac aagcagattt tcagaaagcc tcagcaaaaa 2460ctgggagatg aagatgaaga aattgatgga gataccaata aatacaagaa aggacgtaag 2520aaagcagctt atgctggagg cttggttttg gaccccaaag ttggttttta tgataagttc 2580attttgcttc tggacttcaa cagtctatat ccttccatca ttcaggaatt taacatttgt 2640tttacaacag tacaaagagt tgcttcagag gcacagaaag ttacagagga tggagaacaa 2700gaacagatcc ctgagttgcc agatccaagc ttagaaatgg gcattttgcc cagagagatc 2760cggaaactgg tagaacggag aaaacaagtc aaacagctaa tgaaacagca agacttaaat 2820ccagacctta ttcttcagta tgacattcga cagaaggctt tgaagctcac agcgaacagt 2880atgtatggtt gcctgggatt ttcctatagc agattttacg ccaaaccact ggctgccttg 2940gtgacataca aaggaaggga gattttgatg catacgaaag agatggtaca aaagatgaat 3000cttgaagtta tttatggaga tacagattca attatgataa acaccaatag caccaatctg 3060gaagaagtat ttaagttggg aaacaaggta aaaagtgaag tgaataagtt gtacaaactg 3120cttgaaatag acattgatgg ggttttcaag tctctgctac tgctgaaaaa aaagaagtac 3180gctgctctgg ttgttgagcc aacgtcggat gggaattatg tcaccaaaca ggagctcaaa 3240ggattagata tagttagaag agattggtgt gatcttgcta aagacactgg aaactttgtg 3300attggccaga ttctttctga tcaaagccgg gacactatag tggaaaacat tcagaagagg 3360ctgatagaaa ttggagaaaa tgtgctaaat ggcagtgtcc cagtgagcca gtttgaaatt 3420aacaaggcat tgacaaagga tccccaggat taccctgata aaaaaagcct acctcatgta 3480catgttgccc tctggataaa ttctcaagga ggcagaaagg tgaaagctgg agatactgtg 3540tcatatgtca tctgtcagga tggatcaaac ctcactgcaa gtcagagggc ctatgcgcct 3600gagcagctgc agaaacagga taatctaacc attgacaccc agtactacct ggcccagcag 3660atccacccag tcgtggctcg gatctgtgaa ccaatagacg gaattgatgc tgtcctcatt 3720gcaacgtggt tgggacttga ccccacccaa tttagagttc atcattatca taaagatgaa 3780gagaatgatg ctctacttgg tggcccagca cagctcactg atgaagagaa atacagggac 3840tgtgaaagat tcaaatgtcc atgccctaca tgtggaactg agaatattta tgataatgtc 3900tttgatggtt cgggaacaga tatggagccc agcttgtatc gttgcagtaa catcgattgt 3960aaggcttcac ctctgacctt tacagtacaa ctgagcaaca aattgatcat ggacattaga 4020cgtttcatta aaaagtacta tgatggctgg ttgatatgtg aagagccaac ctgtcgcaat 4080cgaactcgtc accttcccct tcaattctcc cgaactgggc ctctttgccc agcctgcatg 4140aaagctacac ttcaaccaga gtattctgac aagtccctgt acacccagct gtgcttttac 4200cggtacattt ttgatgcgga gtgtgcactg gagaaactta ctaccgatca tgagaaagat 4260aaattgaaga agcaattttt tacccccaaa gttctgcagg actacagaaa actcaagaac 4320acagcagagc aattcttgtc ccgaagtggc tactccgaag tgaatctgag caaactcttc 4380gctggttgtg ccgtgaaatc ctaagggaat cccaggagta accaaggagg gggtagttga 4440aaaatcccag cttcctctgt gcctccactc tggccctaaa tgctcctcca gcatctgttt 4500ctcccttggg actgtgtctc atgtttgtgt gaatgtagac caggaaaggg ggctgcaaaa 4560atgttgagtc taatgttcgt aagcatcata gaaattcctg tcttcatatt aagatgtact 4620gctttaaaac acaactccag agcccctccc caagctcccc tccccaagct cctgaagacc 4680cggtttctga gggagggaaa ttgctacttg gattgagagt agctggaatg taagtgaccc 4740caggctttgc ctcagggcct ttagcctatg tcccccccac ataaagagag cttctcagag 4800cctgactgaa gagctgacgt tttgcttttt catatgccaa ttaaacccgg tctaaatcca 4860aatgcttctc cagccatcca ggagtggctg tccttttcag tcttgtcttt tatataggta 4920gctgaggggg aagatttaga agccttgcac tcactaaata gattaaacag agcaggcttg 4980tttgttgaat tgctccaaag tccaacagac acacactgag caggtgtttt acactcacat 5040tccctttttg ccccttaaat agaaagtgca ggtaaaggtt tatacaacaa gaaagcacat 5100tgaaaataat ttgatactct aacaatccat taacatgtgt aggggttacg gtgaggatca 5160ctgtgttgta ttcagaaaaa cggggagagg gatgcttaat tggccctggc gcttgctatt 5220tttttctcat ttcttcacaa taggaccgtc tttggcagca gcaaaatgta tttcagtatg 5280gcagtctttc ctctcttaca ttattggtaa gattatacta acaaaatgtt tccccttgta 5340caattatgct gtgtttttaa aaaacattga cctgtgtgtt tttataaaag aaaaagtatg 5400ttgtgccttc ttcttaagaa taaagttttc taaagggaaa aaaaaaaaaa aaaaa 5455728412DNAHomo sapiens 72agccgcgtca acggcccttc gcagcgggcg cgctgtcaga cctcagtctg gcggctgcat 60tgctgggcgc gccgctctcg tctgatccct gctggggacg gttgcccggg caggatcctt 120tacgatccct tctcggtttc tccgtcgtca cagggaataa atctcgctcg aaactcactg 180gaccgctcct agaaaggcga aaagatattc aggagccctt ccattttcct tccagtaggc 240accgaaccca gcattttcgg caaccgctgc tggcagtttt gccaggtgtt tgttaccttg 300aaaaatggct actggacagg atcgagtggt tgctctcgtg gacatggact gtttttttgt 360tcaagtggag cagcggcaaa atcctcattt gaggaataaa ccttgtgcag ttgtacagta 420caaatcatgg aagggtggtg gaataattgc agtgagttat gaagctcgtg catttggagt 480cactagaagt atgtgggcag atgatgctaa gaagttatgt ccagatcttc tactggcaca 540agttcgtgag tcccgtggga aagctaacct caccaagtac cgggaagcca gtgttgaagt 600gatggagata atgtctcgtt ttgctgtgat tgaacgtgcc agcattgatg aggcttacgt 660agatctgacc agtgctgtac aagagagact acaaaagcta caaggtcagc ctatctcggc 720agacttgttg ccaagcactt acattgaagg gttgccccaa ggccctacaa cggcagaaga 780gactgttcag aaagagggga tgcgaaaaca aggcttattt caatggctcg attctcttca 840gattgataac ctcacctctc cagacctgca gctcaccgtg ggagcagtga ttgtggagga 900aatgagagca gccatagaga gggagactgg ttttcagtgt tcagctggaa tttcacacaa 960taaggtcctg gcaaaactgg cctgtggact aaacaagccc aaccgccaaa ccctggtttc 1020acatgggtca gtcccacagc tcttcagcca aatgcccatt cgcaaaatcc gtagtcttgg 1080aggaaagcta ggggcctctg tcattgagat cctagggata gaatacatgg gtgaactgac 1140ccagttcact gaatcccagc tccagagtca ttttggggag aagaatgggt cttggctata 1200tgccatgtgc cgagggattg aacatgatcc agttaaaccc aggcaactac ccaaaaccat 1260tggctgtagt aagaacttcc caggaaaaac agctcttgct actcgggaac aggtacaatg 1320gtggctgttg caattagccc aggaactaga ggagagactg actaaagacc gaaatgataa 1380tgacagggta gccacccagc tggttgtgag cattcgtgta caaggagaca aacgcctcag 1440cagcctgcgc cgctgctgtg cccttacccg ctatgatgct cacaagatga gccatgatgc 1500atttactgtc atcaagaact gtaatacttc tggaatccag acagaatggt ctcctcctct 1560cacaatgctt ttcctctgtg ctacaaaatt ttctgcctct gccccttcat cttctacaga 1620catcaccagc ttcttgagca gtgacccaag ttctctgcca aaggtgccag ttaccagctc 1680agaagctaag acccagggaa gtggcccagc ggtgacagcc actaagaaag caaccacgtc 1740tctggaatca ttcttccaaa aagctgcaga aaggcagaaa gttaaagaag cttcgctttc 1800atctcttact gctcccactc aggctcccat gagcaattca ccatccaagc cctcattacc 1860ttttcaaacc agtcaaagta caggaactga gcccttcttt aagcagaaaa gtctgcttct 1920aaagcagaaa cagcttaata attcttcagt ttcttccccc caacaaaacc catggtccaa 1980ctgtaaagca ttaccaaact ctttaccaac agagtatcca gggtgtgtcc ctgtttgtga 2040aggggtgtcg aagctagaag aatcctctaa agcaactcct gcagagatgg atttggccca 2100caacagccaa agcatgcacg cctcttcagc ttccaaatct gtgctggagg tgactcagaa 2160agcaacccca aatccaagtc ttctagctgc tgaggaccaa gtgccctgtg agaagtgtgg 2220ctccctggta ccggtatggg atatgccaga acacatggac tatcattttg cattggagtt 2280gcagaaatcc tttttgcagc cccactcttc aaacccccag gttgtttctg ccgtatctca 2340tcaaggcaaa agaaatccca agagcccttt ggcctgcact aataaacgcc ccaggcctga 2400gggcatgcaa acattggaat cattttttaa gccattaaca cattagtgct gccctcaggc 2460ttgcctgtag gatttaatat tttttatctt tacagatctt tatctttaat attttatctt 2520tacagatttc cctgagaaag ggaattatga aatttttaat acaaaaaata atccatttag 2580gtgctgagtt acggtcccat ctcttcacag gcatggattc taatcccact gctgacagag 2640atgtaaaaat tcatcctacc agagttttta atctttagca tttagggagg cagtgtcata 2700aagtaaaaag tgtgtgggcc ttggagtcta agagacgtgg ttgcaaactt agctctggtt 2760attgcaatga gggccttgaa caagtcattt tcttcacatt ctcatctgta aaatggagat 2820aataccttac agattattgc agattaataa caatgtattc aaattatgta actcggccgg 2880gtacaatggc tcacgcctgt aatcctaaca ctttgggagg ccgaggcaga cagatcacct 2940gaggtcagga gtttgagacc agcctggcca acatggcaaa accatctcta ctaaaaatag 3000aaaaattagc caggcacgtt ccaggcacct gtgatcccag ctacttagag gctgaggcag 3060aagaattgct ttaaccttgg aggcggaggt tgcattgagc tgagatcatg ctagtgcgct 3120ccagcctggg caacagagcg agacttcatc tcagaaaata aaaaataggg gccaggcaca 3180gtggctcata cctgtaatgc cagcactttg ggaggccaag gcgggcagat cacgaggtca 3240ggagtttcag accaatatgg tgaaacccca tctctactaa aattacaaaa aaaattatcc 3300aggcgtggtg gtgcacgcct gtaatcccag ctactcagga ggctaaggca ggagaatcac 3360ttgaacccag gaggcagagg ttggagtgag ctgagatcgc gccaccgcac tccagcctgg 3420gcaacagagc gagactccat ctcaaacaaa aacaagaaca aaaacaaaca taaagttggc 3480acagaaaagg gaccaagttt aaaaaagggt tttaaatgta atgagacttg catagttaaa 3540aaaaaaaaag ggattatttt tatttttatt ttttattttt gagacggagt ctccctctgt 3600cgtcaggcta gaatgcagtg gtgcgttctc agctcaccgc aacctccgtc tcctgggttc 3660aagcaattct cctgcctcag cctcccaagt agctgggact acaggcacgt gctaccacac 3720tcagctaatt tttgtatttt taatagagat gaggtttcac catgttggcc aggatggtct 3780cgattgcttg acctcatgat ccgcctgcct cgacctccca aagttgctgg gattacagat 3840gttagccacc gatcctggcc cccccaaaaa aaggatttta agaaaaactt ctcttggccg 3900ggcgcagtgg ctcacgcctg caatcccagc actttgggag gccgaggcgg gcggatcaca 3960aggtcaggag atcgagacca cggtgaaacc ccgtctctac taaaaaatac aaaaaaaaat 4020tagccgggtg cggtggcagg cgcctgtagt cccagctact cgggaggctg aggcaggaga 4080atggtgtgaa cccgggaggc ggagcttgca gtgagccgag agcgcgccac tgcactccag 4140cctgggtgac agagcgagac tccgtctcaa aaaaaaaaaa aaaagaaaaa cttctcttta 4200ggctgggtgc ggttcctcat gcctataatc ccagcattta gggaggctga ggtgagtgga 4260ttgcaggagc tcaggagttc gagaccagcc tgggcaaggt ggcaaaaccc cgtctctact 4320aaaaaaaatt agctgggctt ggtggcaggc gcctgtaatc ccaggtactc gggagactga 4380ggcaggagaa ttgcttgaac ctggaaggtg gaggttgcag tgagttgaga tcacaccaat 4440gcactccagc cagggtgaga gtgagagact gtctcaaaaa aaaaaaaaac aaaagaaaaa 4500cttctctcta gctctgtgac gggcagttca gataatacct tcaccagatt tacctgtttt 4560cagctgaaga atgtgagatg aagccttgaa accctaaaag tgatatggta actagggcag 4620gtctttctgt acataaaagt gacttaataa acagtgaatt tcatacaggt aaaccctatt 4680ataccctcag ttctaaccat tggcctatct cttgcgtttt gttctaatgt agaattagat 4740tgctacttga ctagttcagg aactctgttt agatctgata agtcataatc aaatcttgcc 4800aggcgtggtg gtttatgcct gttatcccag cactttggga ggccaaggca ggtggaccac 4860gtgaagtcag gagttcaaga caagcatggc caacatggcg aaaccctgta tctactaaaa 4920atacaaaaat tagccgggca tggtggtggg tgcgtgtaat cccagctagt tgggaggctg 4980aggcaggaga atcacttgaa cctgggaggc agaggttgca gtgagccgag atttccactg 5040cattccagcc tgggcgatag agtaactctg tctcaaaaaa acccactaga tcatctctag 5100aacattgcta ctcccaagta tgatttgagg aacagcagcc tcagtatcac cagggaactt 5160attagaaata gtctcagcct caccactatt cccacttaat tgtaatctga tattaacaag 5220atttcccaat gtgggtcagg tgtggtggct catgcctgta atcccacact ttgggaggcc 5280aaggtgggcg gatcacttga ggctgggagt ttgagaccag gctggccaac atggggaaaa 5340cccatctcta caaaaaataa caaaaattag gtgtgtgtgg tgacgcatgc gtgtaatccc 5400agctacttag gaggctgagg caggagaatc acttgaatct gggaggcaga ggttgtagtg 5460agctgagatt gtgccactgc actccagtct gggcaacaga gtgacactgt ttaaaaaaaa 5520aaaaattccc aatgtgggcc gggtgcagtg gctcatgcct gtaatcccag cactttggga 5580ggctgaggtg ggtgtatcac gaggtcaaga gatcaaggcc atcctggcca acatggtgaa 5640accccgtctc tactgaaaat acaactgggc gtggtggtgc acgcctgtag tcccagctac 5700ttgggaggct gaggcagaag aattgcttga cctgggaggc ggagcttgca gtgagcccag 5760atcgtgccac tgcactgcac cctggcgaca cagcaagact gtctcaaaaa aaaaaaaatt 5820cccaatgtgt atcttaaagt ttgagaaatg ctgatctaaa agatactaat gaccaggtgt 5880gtagaggaca ttttcttaag cccttaagta caaatttaag aggtaagtgc ttcagccatt 5940agggttactg gcttgttcat ctttcccact gagtgtaaat atttagctta gggtttaaaa 6000tttgttatgt agctttttgc acttgtccat gtttatacta ctgtattatt attatttttt 6060tttgagatgg agtctcgctg tgtagccagg ctggagtgca gtggtgcaat cttggctcac 6120tgcaacctcc gtctctcggg ttcaagcaat tctcctgcct cagcttcccg aatagctgag 6180actacaagcg tgcaccacca tgcccagcta atttttgtat ttttagtaga gacaggtttt

6240caccatgttg gccaggctgg tctctatcta gacctcgtga tccatccgcc tcggcctccc 6300aaagtgctgg gattataggc atgagccacc acgcccagcc tatagtactg tattcttatt 6360ctccactctt gtgtgtgaaa agtcagctct tttggctttt ctgttatggg gaaacttgaa 6420ttacacaggg aacccaactg aagaaaatga actgaagtag gtggcgctgg gtgaagtggg 6480cccagagaat ggtgtacaca tccctcccat acatataccc aaacttctat ttttttatgt 6540gacggagttt ctctcatcgc cccggctgga atgcaatggc acgatctcgg ctcactgcaa 6600cctccgcctc ccgggttcaa gcgattctcc tgcatcagcc tcctgagtag ctgggattat 6660aggcatgcac catcacgcct ggctaatttt tgtattttta gtagagatgg ggtttcgcca 6720cgttggccag gctggtcttg aactcttgat ctcaagtgat ccacccgccc tggcctccca 6780aagtgctggg attacaggcc tgagccacca ggccagcccc aacttctact ttttatttta 6840tttataaatt gggggggggg ttctatattt agtttgaaga ggtggggaag atttgaaaac 6900cactagattt accaggaaat ttttttcttc aaaaatattt tctgctttta tgatacttga 6960atatctaata aaagacaata tttagccagt cacggtggct gatgcttgta atcctaacac 7020tttgggaggc tgaggtgggt ggactactgg agccctggag ttcaaaaccg gcctaagcca 7080catggcaaaa cagtctttac aaaaaataca aagatggtgg cttatgcctg tagtcgtacc 7140tactcaggag gctgaggttg ggaggatcac ctgaatctgg gagtttgggg ctgcaataag 7200ccatgattgt gccgctgcac tccagcctgg gtgacagtct gagaccctgt ctcaaaaaaa 7260aaaaaaaaaa aaaaaaaaaa aaagactaca ttcactgtat acgtggcctt ttccccctaa 7320ctagctatgt agcttcttaa aggcaaagat tcttcatagt gctttgcaca tgataggtgc 7380tgatactcat tggatgaatg tatatagtga agaattttag atctgattac cacaattggg 7440atcataaaca tgtataaact ccttgggagt ctgccttata tactttttat ccccctaaat 7500gttccattaa tgttgcagag aggctcacta gttcctggag atgtcttatt aagtactgaa 7560atgtgatttt ccaaaatttt ctttacaata caggcaaaag ataagtaaat tgtggacaaa 7620gctttcatct ctatcagcag ctatagagag gaagtaaaca gcttagcccc taatacagga 7680ggaagttgtt caactacagg cttgttagta gcaagttaaa ccagttacat tttataaaac 7740agcctgagtg gtagggaagc tatcacttta atactctaga ggcagaatgc cacataggac 7800tttgggtcac atatttcttt tccagggtct cctcaaaatg cagtttctat ttacagttga 7860ctttggcccc tatttaccca taaaatgtca aaatcaagta gtatgaacat ggaaacagga 7920gcagggacta aggtttggtc aagtggccct cattgttcca agagtaattt aggctatgta 7980aacttgaaaa atatgggacc agattacctt ttgtctctaa attctactct tctttaagta 8040gctggcactg tatctctgcc agggcacaga agtgggctcc ttactattct gaccactagc 8100aagtggccaa ctcttcaaat acagggtagc tacctatttc acgtgaaagg cctcagtatt 8160ctgctcactt gaactacgga aaataggcca caatacttgg ttacaatact ggaactctga 8220acctatgtgg aggagagaaa aacaatggtg aacgagatac cagctgggct ctttccacat 8280tcagggctca gcagtgttgg ggtttcactt gtctctaatc ctgaagaggt atctagccct 8340ggaaggaagc tgagcctgta gctaacgcat aagcacagtg tattcaataa aacattttta 8400ttctgtacaa ta 8412732866DNAHomo sapiens 73ggattcggcg caggcgcagt ccgcgcgggt tctcgcgcgg agaaggggtg cgagcggcgg 60cggcggcgga ggctgccatg gacgacgagg aggagacgta ccggctctgg aaaatccgca 120agaccatcat gcagctgtgc cacgaccgtg gctatctggt gacccaggac gagcttgacc 180agaccctgga ggagttcaaa gcccaatttg gggacaagcc gagtgagggg cggccgcggc 240gcacggacct caccgtgctg gtggcccaca acgatgaccc caccgaccag atgtttgtgt 300tctttccaga ggagcccaag gtgggcatca agaccatcaa ggtgtactgc cagcgcatgc 360aggaggagaa catcacacgg gctctcatcg tggtgcagca gggcatgaca ccctccgcca 420agcagtccct ggtcgacatg gcccccaagt acatcctgga gcagtttctg cagcaggagc 480tgctcatcaa catcacggag cacgagctag tccctgagca cgtcgtcatg accaaggagg 540aggtgacaga gctgctggcc cgatataagc tccgagagaa ccagctgccc aggatccagg 600cgggggaccc tgtggcgcgc tactttggga taaagcgtgg gcaggtggtg aagatcatcc 660ggcccagtga gacggctggc aggtacatca cctaccggct ggtgcagtag ctaccgcctg 720acagccccta gaggcggaca cacagcgacc cccatccctg caggacaaac gcccctgccc 780tgccagaatc cggcccccac agctctcacg gctgctgctc ctctggactc cccaaggcag 840gtggcctcca cccacgttct cccgtcctgg ggtgaggctt cctgtggccc agcccgcccc 900attcacctgt ggatttgtgc gagatgcagc ctcagaagga acaaggcccc cagagggagg 960tcacctgggg gcagctggtg ccgggtcttc acccagacca cgctgggtcc cctctgttgg 1020gggtttgggg tccgggtctc ccaccagcca ctgcttcctc ctgggccctc ggccttccac 1080ccctcgtctt ccctccctcg ggggccctga tgcgtggcgg cccccgcccg gcctcggctc 1140tttactccat tcacagccat gcacgcgctc aagccaccag ggtgcgagat gccagctctg 1200gagttctcgg ttgttgtagg aggttgggtg ttttcaaatg gtaaagatgt tttgagcaaa 1260taaatttgct tgatacagaa accaggccga ctaacaaggt ttccagcagg tggccttgcc 1320tcaccccaag cacacgaggt cagcctggca ggtgtgccct cctcgcgctg gcttcagggg 1380tcagtgtctc cccaggccct cgccctgccc tcccacttcg tgctcctggg taaggcgtga 1440gcgtgtctgt ctcttccctt cccgtgaggg tgtggagttg ttctctggct tgtgcagctg 1500tggtttgcgg ccagttcctc ttacagacgt ttgggatctg gctctacttc cccgtttgct 1560tactgtctga tttcagaagg cctcgcctgc ccaagtttaa cctagccacg tggttctctc 1620acagtagctt tattaagatg taattcaccc tcgggcggtc ggtggtctgt aacgcgccca 1680ctgttctgtg cagcagggtc cccagatccc caggccgcgg actgtgtgtg tgatggggac 1740agtgcttccc cttctctcca aatgtacttt tttcaaaatt gtcttggcca aagcaagcca 1800gacccaaagg gacaaacact gatgtcactc ctaggaggtc actagagtcg tcagagactg 1860gaagtaggat gggggttccc gggactgggg agttgggtgg ggatgggggt tcccagggct 1920ggggaggagg gaggggacag agtgtgtcat gtgcacagtt ttagtttggg aagatgagaa 1980aattctggag gtggccgggc gcggtggctc acgcctgtaa tcccagcact ttgggaggcc 2040gaggtgggcg gatcacctga ggtcgggagt tcgagaccag cctgaccaac atggcaaaat 2100cccatcactg caaaaaatac aaaaattacc tgggcgtggt ggtgcatgcc tgtaatccca 2160gctacttggg agctaaggca ggagaatcac ttgaacccag gaagtggagg atcgcttgag 2220ctcaggagtt aaaagaccag cccgggcaac acagagaaac cccccacctc tacaaaaaac 2280tttaagatta cctgggcaca gtggctcaca cctgtaatcc caacactttg ggaggctgag 2340gcgggaggat catttgagcc caggaggccg aggctgcagt gagctacgat tgtgctcctg 2400tactccagcc tgggccacag ggtcacaccc tgtctcaaaa aaaaaaaaaa atgcagttcc 2460acaggcgcat gggccacgtt tccagtgctt ggtggccatg tggggctgac gtgcgaaacc 2520ttagagccgg gggatacgtc cgtcatcgag aacgttttcc tggactgccc tgggctgcag 2580gtggacgtga cgaggtcatt cgatgcctga ccgtctgcac agcctgtggt gaagaccacc 2640cgggctccca cctcgcgggg ccccgtggcg gggggttccc ttcctcacac atccctcccc 2700tagggggagg cccagggcca cgccacgggg ctctctctgt cccctccctg gccccttctt 2760ctaagcttgc agctgccaca gaaaatcttc taagcttgca gctgccacag aaaacacccg 2820attaaaaact ttttatttca gcaaaataaa cgtgcctgtg aaagaa 286674885DNAHomo sapiens 74ggcccgggaa aggaccagaa caggcggcga agactgaagc ccggaggtag gagtggcaag 60agctcgccca gtccgcgaag ggtaaactcg cgcatgcgca ctggccttca accaagccaa 120gcgccttggc ttctgtcctg gatgctcagt gttttgcggt ttacgatgcg catcgttttc 180ccggctctgg caccagatcc atactattct gtaaactgag gcggcgatgc ccaaaaattg 240gaagcaatta ctctaagata tcaaaagatt gaagcaagcc atgaaacctc tgcgcggaga 300gagccgagcc cgaggcggcg gggagccagc acgtgtgcgc agctccgccc tcttttggcg 360aagcacctag gcctggcccc tcccgcgacc tgtagcgcgg cggagcaagc gcggaaggct 420gggagggctg cgcgggctgc gcgtcgccat ggagcccgac gggacttacg agccgggctt 480cgtgggtatt cgcttctgcc aggaatgtaa caacatgctg taccccaagg aagacaagga 540gaaccgcatt ctgctctacg cgtgccggaa ctgtgattac cagcaggagg ccgacaacag 600ctgcatctat gtcaacaaga tcacgcacga agtggacgaa ctgacccaga ttatcgccga 660cgtgtcccag gaccccacgt tgccgcggac cgaggaccac ccgtgccaaa agtgcggcca 720caaggaggct gtgttcttcc agtcacacag tgcgcgggcc gaggacgcca tgcgccttta 780ctacgtgtgc acagccccac actgcggcca ccgctggacc gagtgacctc ctctctcccc 840cgagtgtaat aaacaccaga ttccatgcgt gaaaaaaaaa aaaaa 885753207DNAHomo sapiens 75gattgcgcac ccgcgacttc agcccgaggg gcggggattt tcttggagcg acgggacgcg 60acgccaatcg cgacgaggct tcgccccgtg gcgcggtttg aaattttgcg gggctcaacg 120gctcgcggag cggctacgcg gagtgacatc gccggtgttt gcgggtggtt gttgctctcg 180gggccgtgtg gagtaggtct ggacctggac tcacggctgc ttggagcgtc cgccatgagg 240agaagtgagg tgctggcgga ggagtccata gtatgtctgc agaaagccct aaatcacctt 300cgggaaatat gggagctaat tgggattcca gaggaccagc ggttacaaag aactgaggtg 360gtaaagaagc atatcaagga actcctggat atgatgattg ctgaagagga aagcctgaag 420gaaagactca tcaaaagcat atccgtctgt cagaaagagc tgaacactct gtgcagcgag 480ttacatgttg agccatttca ggaagaagga gagacgacca tcttgcaact agaaaaagat 540ttgcgcaccc aagtggaatt gatgcgaaaa cagaaaaagg agagaaaaca ggaactgaag 600ctacttcaag agcaagatca agaactgtgc gaaattcttt gtatgcccca ctatgatatt 660gacagtgcct cagtgcccag cttagaagag ctgaaccagt tcaggcaaca tgtgacaact 720ttgagggaaa caaaggcttc taggcgtgag gagtttgtca gtataaagag acagatcata 780ctgtgtatgg aagaattaga ccacacccca gacacaagct ttgaaagaga tgtggtgtgt 840gaagacgaag atgccttttg tttgtctttg gagaatattg caacactaca aaagttgcta 900cggcagctgg aaatgcagaa atcacaaaat gaagcagtgt gtgaggggct gcgtactcaa 960atccgagagc tctgggacag gttgcaaata cctgaagaag aaagagaagc tgtggccacc 1020attatgtctg ggtcaaaggc caaggtccgg aaagcgctgc aattagaagt ggatcggttg 1080gaagaactga aaatgcaaaa catgaagaaa gtgattgagg caattcgagt ggagctggtt 1140cagtactggg accagtgctt ttatagccag gagcagagac aagcttttgc ccctttctgt 1200gctgaggact acacagaaag tctgctccag ctccacgatg ctgagattgt gcggttaaaa 1260aactactatg aagttcacaa ggaactcttt gaaggtgtcc agaagtggga agaaacctgg 1320aggcttttct tagagtttga gagaaaagct tcagatccaa atcgatttac aaaccgagga 1380ggaaatcttc taaaagaaga aaaacaacga gccaagctcc agaaaatgct gcccaagctg 1440gaagaagagt tgaaggcacg aattgaattg tgggaacagg aacattcaaa ggcatttatg 1500gtgaatgggc agaaattcat ggagtatgtg gcagaacaat gggagatgca tcgattggag 1560aaagagagag ccaagcagga aagacaactg aagaacaaaa aacagacaga gacagagatg 1620ctgtatggca gcgctcctcg aacacctagc aagcggcgag gactggctcc caatacaccg 1680ggcaaagcac gtaagctgaa cactaccacc atgtccaatg ctacggccaa tagtagcatt 1740cggcctatct ttggagggac agtctaccac tcccccgtgt ctcgacttcc tccttctggc 1800agcaagccag tcgctgcttc cacctgttca gggaagaaaa caccccgtac tggcaggcat 1860ggagccaaca aggagaacct ggagctcaac ggcagcatcc tgagtggtgg gtaccctggc 1920tcggcccccc tccagcgcaa cttcagcatt aattctgttg ccagcaccta ttctgagttt 1980gcgaaggatc cgtccctctc tgacagttcc actgttgggc ttcagcgaga actttcaaag 2040gcttccaaat ctgatgctac ttctggaatc ctcaattcaa ccaacatcca gtcctgagaa 2100gccctgatca gtcaaccagc tgtggcttcc tgtgcctaga ctggacctaa ttatatgggg 2160gtgactttag tttttcttca gcttaggcgt gcttgaaacc ttggccaggt tccatgacca 2220tgggcctaac ttaaagatgt gaatgagtgt tacagttgaa agcccatcat aggtttagtg 2280gtcctaggag acttggtttt gacttatata catgaaaagt ttatggcaag aagtgcaaat 2340tttagcatat ggggcctgac ttctctacca cataattcta cttgctgaag catgatcaaa 2400gcttgtttta tttcaccact gtaggaaaat gattgactat gcccatccct gggggtaatt 2460ttggcatgta tacctgtaac tagtaattaa catctttttt gtttaggcat gttcaattaa 2520tgctgtagct atcatagctt tgctcttacc tgaagccttg tccccaccac acaggacagc 2580cttcctcctg aagagaatgt ctttgtgtgt ccgaagttga gatggcctgc cctactgcca 2640aagaggtgac aggaaggctg ggagcagctt tgttaaattg tgttcagttc tgttacacag 2700tgcattgccc tttgttgggg gtatgcatgt atgaacacac atgcttgtcg gaacgctttc 2760tcggcgtttg tcccttggct ctcatctccc ccattcctgt gcctactttg cctgagttct 2820tctacccccg cagttgccag ccacattggg agtctgtttg ttccaatggg ttgagctgtc 2880tttgtcgtgg agatctggaa ctttgcacat gtcactactg gggaggtgtt cctgctctag 2940cttccacgat gaggcgccct ctttacctat cctctcaatc actactcttc ttgaagcact 3000attatttatt cttccgctgt ctgcctgcag cagtactact gtcaacatag tgtaaatggt 3060tctcaaaagc ttaccagtgt ggacttggtg ttagccacgc tgtttactca tacagtacgt 3120gtcctgtttt taaaatatac aattattctt aaaaataaat taaaatctgt atacttacat 3180ttcaaaaaga aaaaaaaaaa aaaaaaa 3207762846DNAHomo sapiens 76gtaatcagtc caaaaaccag cgtgccaaag cgtttcccca gggctctgtc cggactctga 60agcactgcat aaaggggtct gtctgagccc aatttacttc cggtggggaa gggaaaggga 120agacaccacc ggaagcaagg aaggtgctgt gtaatcatta aggagcggag gcttttggag 180ctgctaaaat gccggattac ctcggtgccg atcagcggaa gaccaaagag gatgagaagg 240acgacaagcc catccgagct ctggatgagg gggatattgc cttgttgaaa acttatggtc 300agagcactta ctctaggcag atcaagcaag ttgaagatga cattcagcaa cttctcaaga 360aaattaatga gctcactggt attaaagaat ctgacactgg cctggcccca ccagcactct 420gggatttggc tgcagataag cagacactcc agagtgaaca gcctttacag gttgccaggt 480gtacaaagat aatcaatgct gattcggagg acccaaaata cattatcaac gtaaagcagt 540ttgccaagtt tgtggtggac cttagtgatc aggtggcacc tactgacatt gaagaaggga 600tgagagtggg cgtggataga aataaatatc aaattcacat tccattgcct cctaagattg 660acccaacagt taccatgatg caggtggaag agaaacctga tgtcacatac agtgatgttg 720gtggctgtaa ggaacagatt gagaaactgc gagaagtagt tgaaacccca ttacttcatc 780cagagaggtt tgtgaacctt ggcattgagc ctcccaaggg cgtgctgctc tttggtccac 840ccggtacagg caagacactc tgtgcgcggg cagttgctaa tcggactgat gcgtgcttca 900ttcgagttat tggatctgag cttgtacaga aatacgtcgg tgagggggct cgaatggttc 960gtgaactctt tgaaatggcc agaacaaaaa aagcctgcct tatcttcttt gatgaaattg 1020atgctattgg aggggctcgt tttgatgatg gtgctggagg tgacaatgaa gtgcagagaa 1080caatgttgga actgatcaat cagcttgatg gttttgatcc tcgaggcaat attaaagtgc 1140tgatggccac taacagacct gatactttgg atccagcact gatgaggcca gggagattgg 1200atagaaaaat tgaatttagc ttgcccgatc tagagggtcg gacccacata tttaagattc 1260acgctcgttc aatgagtgtt gaaagagata tcagatttga actgttagca cgactgtgtc 1320caaatagcac tggtgctgag attagaagcg tctgcacaga ggctggtatg tttgccatca 1380gagcacggcg aaaaattgct accgagaagg atttcttgga agctgtaaat aaggtcatta 1440agtcttatgc caaattcagt gctactcctc gttacatgac atacaactga accctgaagg 1500ctttcaagtg aaaactttaa attggaatcc taaccttata tagacttgtt aataaccaat 1560tcataaacaa ataaatggct tcaaaattgt atgctttttt ccatatctct tcttgtaata 1620taataaaagg tgatttctaa tgttattagg cagaaaagct tgttagaata tattttgact 1680atttttttga cccacacccg tttaaggatt tcacatcata caaagcgctt gcttagatgg 1740cttctatcct aggcatatgc tggccgggtg ctctacatat aaattctcat tgtatcctcc 1800catctgtcca ctgaggaaga ttatcaaatg gatcttcatc caatggatgc ataaactttc 1860ctacttactt gtagtggcaa agctggcttt caagtacaag tttgttggct ccattaccta 1920tgctcctatt atccgcttct gtcccgcaac aaagtagctc acttaggcgt atgaccacat 1980gcattatgat agtttcccac caccatattg aataataaaa gctttggcca aagctttttt 2040aaagtaggag aaacattgga tgtatatgtt ttgcattgcc atttgatttc aaattaatca 2100ggaagaatta gtgattttaa tgagcagtaa agtggtgcaa taaagcagaa agaaaaatgt 2160tcagccagaa gtgaaagact agtaaaaaaa gaaaaaaaaa tatttgtaca tatgatctaa 2220tttagaaagt ccagaattgg cttcatacag aaaagtgatt actttcattt tacaaattac 2280tttaaaattt tggtaaagtt tctgttaggc ttctggtcta cagtgaggta ttttaaaaat 2340aaaggttata ttagaatcct caacatctct ttaaaattac ctcctgtgta accaccacca 2400aatcctatct tctaccacaa ttaccccttc ccccaatgcc aagaccaaag cacaataatg 2460aatattttta ttgaagttcg atattcataa ataagttgca aaataagagt tggatatatt 2520tttaattcac aatagaaaaa gttgacaaca tagaaaatgc tgctttgcac tgaaatactt 2580aaaattatga aagttttcaa gtaaagaaat taaagccttt tataaaatcc aaccaacatt 2640cttgattttt catttttatg aacttgatca gaaaaattca tcttttttaa ccctgcccta 2700atttttcttg aggaattaaa tagagcaaac tattttcagg ttatgcttac aataaaatat 2760acttaagaaa atgactgaag atgtatgttt ttgaatgttt tgattaaata aatgtacaca 2820tttagaacac aaaaaaaaaa aaaaaa 2846773925DNAHomo sapiens 77agcggggctg cgcgaagtca tcgctgttcc agacagcgat gactcgagag cggtgggggt 60ggcggcgcga tcggccgggc tgtaaccgtc gtctgtccgg gagcggctgg agcggcagcg 120gcggccgggc acggcgcgag gtgacgccac agggcagcgg cggcagcgga ggcagcggcg 180gcagcaggag acgcagcggc ggccgcagca gcagcagcaa gacggactcg tggagacgcg 240ccgccgccgc cgccgccggg ccgggccggg tgtcgcgcgc cgaggctggg ggggagtcgt 300cgccgccgcc gccaccgcta ccgccgccgc cgccgccgcc gaggtgactg aggagagagg 360cgcctcctcg ctcccgccac cgccggactt caatgcccag tccccagctc gccagcgttt 420ttcgttggaa tatacgttgc acatttatgg cgattctgag tgtgagggca gacttctgcc 480aggctcagca cagcattttc gctgacaagt gagcttggag gttctatgtg ccataattaa 540cattgccttg aagactcctg gacaccgaga ctggcctcag aaatagttgg cttttttttt 600tttttaattg caagcatatt tcttttaatg actccagtaa aattaagcat caagtaaaca 660agtggaaagt gacctacact tttaacttgt ctcactagtg cctaaatgta gtaaaggctg 720cttaagtttt gtatgtagtt ggattttttg gagtccgaat atttccatct gcagaaattg 780aggcccaaat tgaatttgga ttcaagtgga ttctaaatac tttgcttatc ttgaagagag 840aagcttcata aggaataaac aagttgaata gagaaaacac tgattgataa taggcatttt 900agtggtcttt ttaatgtttt ctgctgtgaa acatttcaag atttattgat tttttttttt 960cactttcccc atcacactca cacgcacgct cacacttttt atttgccata atgaaccgtc 1020cagcccctgt ggagatctcc tatgagaaca tgcgttttct gataactcac aaccctacca 1080atgctactct caacaagttc acagaggaac ttaagaagta tggagtgacg actttggttc 1140gagtttgtga tgctacatat gataaagctc cagttgaaaa agaaggaatc cacgttctag 1200attggccatt tgatgatgga gctccacccc ctaatcagat agtagatgat tggttaaacc 1260tgttaaaaac caaatttcgt gaagagccag gttgctgtgt tgcagtgcat tgtgttgcag 1320gattgggaag ggcacctgtg ctggttgcac ttgctttgat tgaatgtgga atgaagtacg 1380aagatgcagt tcagtttata agacaaaaaa gaaggggagc gttcaattcc aaacagctgc 1440tttatttgga gaaataccga cctaagatgc gattacgctt cagagatacc aatgggcatt 1500gctgtgttca gtagaaggaa atgtaaacga aggctgactt gattgtgcca tttagaggga 1560actcttggta cctggaaatg tgaatctgga atattacctg tgtcatcaaa gtagtgatgg 1620attcagtact cctcaaccac tctcctaatg attggaacaa aagcaaacaa aaaagaaatc 1680tctctataaa atgaataaaa tgtttaagaa aagagaaaga gaaaaggaat taattcagtg 1740aaggatgatt ttgctcctag ttttggagtt tgaatttctg ccaggattga attattttga 1800aatctcctgt ctttttaaac tttttcaaaa taggtctcta aggaaaacca gcagaacatt 1860aggcctgtgc aaaaccatct gtttggggag cacactcttc cattatgctt ggcacataga 1920tctccctgtg gtgggatttt ttttttccct ttttttgtgg gggagggttg gtggtatatt 1980tttcccctct tttttccttc ctctcctaca tctccctttt cccccgatcc aagttgtaga 2040tggaatagaa gcccttgttg ctgtagatgt gcgtgcagtc tggcagcctt aagcccacct 2100gggcactttt agataaaaaa aaaaaaaaac aaaaaacaac accaaaaaaa cagcagtgat 2160atatatattc caggtggttt ttagtcttta ctgatgaaag ggtgttcatg ttagtttctt 2220caaaacccta tctaatacta ggcaaagtag ccaagagcct tttgttttgt ttttattttg 2280ataaattagt ggagaaatgg cattttaaga ggagtctctt ctcaacttac ctgagagtcg 2340aattcttctc ttccctaacc aatgaagcta agtggttatc ccagaaactt gtcttctaaa 2400agggaggact ccaggccatc aataaagatg tccaggcagt gagcgtactt tttacaccct 2460gtagaattgt gggctgtagc gttactctga ttttctgtct agtatcagag aatgctggta 2520gcttaaaatt tttattttag gacttgtact ctgaattttc aggaaccgtc aaaggagcag 2580cagcaaattc acatattttc gacttgagaa atgcttgtgg tatgtgtttt ccaaactgcc 2640ccctatatgt aaagttcagt ttaaccactg attgccttgt tattactagg ttttttgaga 2700ttaaaaaaaa aaaatccctg gtttaaaacc aacaatgatg cctagtgagt atgtgtccac 2760aggccataac agggtagaag agagacatcg tgcaacccaa tgagtagtga agggactgtg 2820ttgcttgtga agcggtgtag

tagcattttt gcagattctt ggctgggttt agtgtactga 2880tctagaaaag ctgtttttct gctcctttgt ggaaggcagt tatgatcagg ctgcatggac 2940aaagcaggta gaggggcacc atcaggggct cttgcactat tttcacctct aaatattacg 3000tactcagtag tgccctgctt ctagggctct gaatacgggc ttaaagtcat cttgtcctgc 3060tggaatttgc tgtgcagagc cataagcctc ccattttgtt agcgtcagct aggccaatag 3120gaacagaccg ggaccttgtc tcacactgat gatacctcac atgttgaccg gctatgtgaa 3180ctgcctattt cctatgctgg agttttgatt tttaactaaa cgcaaatctg tagattctct 3240cctctcccat cccagaaaac aaaacaaaat aatgcttttc gaaattgttt ctaggacttt 3300aaaacataat ggtatatcca aaattcttta tttcagaatg caacaataga ttccattaat 3360atagactcaa gatcaaaaca gcatacctgc taagctaaga tagatggtgt tgattccact 3420gggttttgat caatacaata acaaaccttt ttcctttgac atactctgaa ttttgttgtt 3480tggggggagg gggtgtgtgt gtgtgtgtgt gtgtgtgtgt gtattgtgtg tgtgtgtgtg 3540tgcacgcgca gtgtccatca gtatcagtgc ctgcctgagt taggaaaatt acattcctgg 3600ttctgtattg aggagaagga tgtataaagc aacatgaaac attagccctc cttttatttt 3660aaagactaat gttaattgtt cttaaaactg gatttttttt ccttaaagca atttttttct 3720tttcgattta atgaagtatt gctagctgaa gccagtttga catagagaga tgtcagattg 3780atttgaaagg tgtgcagcct gatttaaaac caaaccctga acccttttaa agaacaataa 3840aacatatttt acacgctcaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 3900aaaaaaaaaa aaaaaaaaaa aaaaa 3925783956DNAHomo sapiens 78ggctgaggca gccgcgcagg tcgcagggcc agcgtccgcg aggacggccc ggctgggcgg 60ccccgagctc tgtggcgctg tggaggagcg ggagcgcggc cgagaaagcg gggcgccgag 120ggggtcggcg gccttcggga aatttccgcc gacccttcgc tcccggctct aaaagttcct 180gatttcctat ttccttttaa atcccgagtg gctgttagct cttcgcctgc actttttctt 240ccccaggaga taagggggag tgtgaggaac ggagcgaata atataaaaaa ggatttcctc 300ccggaagaga gcggcagttc ggagagattt ttcttaagga agcagaagcg gcgtttgcgg 360ccgctgcagg cgccgggccc tgccggccac actatgcgcg agccggcccc gggctgctga 420ggcgcgggga cgcggaagcg gaggccgagc gcgccgggct cccgcgctcg cgagcgagtt 480ttgtccgccc ggcggcggtg gcggggggat ggagcccgcg accgcgcccc ggcccgacat 540ggcgccggag ctgaccccgg aggaggagca ggctaccaag cagtttctcg aagagattaa 600caagtggaca gttcagtaca atgtttcccc gctgtcttgg aatgtggctg tcaagttcct 660catggcaagg aagtttgatg tgctccgtgc catagaattg ttccactcct acagagaaac 720tcgaaggaag gaaggcattg taaagctgaa acctcatgag gaacctcttc gttctgagat 780cctcagtgga aaattcacca tcttaaatgt tcgggaccca acaggagcct ccattgccct 840ctttactgcc aggttgcatc atccccacaa gtcagtccaa catgtggtac ttcaggctct 900gttttacttg ctagacagag ctgtggatag ctttgaaact cagaggaatg gactggtgtt 960tatctatgac atgtgtggtt ctaattatgc caactttgag ctggatcttg gcaagaaagt 1020cctaaacctg ctgaagggag catttccagc tcgtttgaag aaggtgctga ttgtgggggc 1080acccatatgg ttccgagtgc cctattccat catcagtctc ctcctgaagg acaaagtccg 1140ggagaggatt caaatattaa agacatctga ggtcacgcag catctgccca gggagtgtct 1200tccagaaaac ctgggtgggt acgtcaaaat tgatctcgcc acttggaatt tccagttcct 1260accccaggtg aacggccacc cagatccctt cgatgagatc atcctgttct ccctccctcc 1320tgccttagac tgggactcag tacatgttcc aggtccccat gctatgacca tccaagagtt 1380ggtggactat gttaatgcca ggcaaaagca aggaatctat gaggaatatg aagacattcg 1440tcgtgagaac cctgttggca ctttccactg ttccatgtct ccaggaaacc tagagaaaaa 1500ccgttatggg gatgtaccct gcctggacca aactagagtg aagctaacaa agcgaagtgg 1560ccatactcag acagattaca tcaatgccag tttcatggat ggctacaagc agaagaatgc 1620ttacattggc acacaaggtc ctttggagaa tacctatcgt gatttctggc tcatggtatg 1680ggagcaaaaa gtcttggtga ttgtcatgac cacccgcttt gaggaaggcg gcaggagaaa 1740gtgtggccag tactggcctt tagaaaaaga ctctcggatc cgatttggct tcctcacagt 1800gaccaatcta ggcgtggaga acatgaatca ttataagaaa acaacgctag aaattcacaa 1860cacagaggaa cggcagaaac gccaggtgac ccacttccag ttcttgagct ggccagacta 1920tggtgtccct tcctcagcag cttccctcat tgacttcttg agagtggtca gaaaccagca 1980gagtctggct gtgagcaaca tgggagcacg ctccaaaggg cagtgccctg agccacccat 2040tgtggtccat tgcagtgcag gcattggcag gacaggtacc ttctgctcac tggacatctg 2100cctggcacag ctggaggagc ttggcaccct taatgtgttc cagacggtgt cacgcatgag 2160gacccagagg gccttcagca tccagacccc tgagcagtac tatttttgct acaaggccat 2220cctggagttc gcagagaagg agggcatggt atcctctggc caaaacctgc tggccgtgga 2280gagtcagtaa ctctcctacg aacctcctac ctgttggcca gccttcctta aactaccctg 2340gacaccgctg agcctatagg ttgccatcag ttacgctgaa gccatggatc aacttctttc 2400ttgtgtctcc cagcacacgt gtgcacgcaa ggcagccttt ccctttggct agataaatgt 2460ggtgaaattg ccactagaaa gggccagtag caatgtgttc ttaattccta gcatctgcta 2520tcaaactgtg ccttattaaa accaaattgt ggctattgat ttttgctagg gtccccgagg 2580taagtgggga aggaacctcc ctcctccttt ctcccgccat tctttttctg aggtctcctg 2640tctcccactc cttccctttc ctaggatttt atggggaggt ttgatgagca tttgcctttc 2700tccccagaga gcttgaccaa gttacatatt ctagagatcg tcctgagtgc caagcacgtt 2760tataagtagg gcgtgtattc cagtcctttc tgtcattctg tgtgtgtgtg tgtgtgcact 2820tatgtgtatg ggtccatatg tacgtgtgta tataatatat attgtatgtg ataatatgat 2880cgtattctat aaatacatat acacacgata ctcctttcca gaagttcctg gggctccgtg 2940ttgcagttca ggactccttg cttcttggac cctactattt atcctggact agcttgggtt 3000ggtgatcatg tctcctcttg tcaggctaca gagtggtgga agaggacaca cacacatctc 3060ctccatgttc ctgccacagg gccccttcct taagtaatga cttatctcct tccagttgcc 3120acctgttgga gccaagaatg tattagtttg tggtgacact gggttagctc agcatggatt 3180tcccttatcc gatgattttt ctacatttac ttggccaatt tggggaacag acctccactg 3240tgattccata ctctctcttt gctttcacta tcccagggat gggaggcgga gggtagagat 3300gaactcactg agcagccaga gccaaatgca atcggtacga atcttagaag gaaggagggg 3360gagcccaggt atgagaaaga aaaaaccact aagaaaatac ctccctggga ggatgagctg 3420gggccctttt tcttttgctg gatggttcct ttatgcagct tggccctgtc taccgagatg 3480cccatctctt cctgcctgct agcctgctag accctcaaac tgggtgggtt ctgtgtcaat 3540aaaaagcttc accccctggc tgagtgaggt ggtcccctgc aatcactgtt tgtcccctac 3600ccacccaacc tgtccctgcc tgctcccagc ccactcatcc ttatgtgcta gggataaatc 3660aagagtcctc agcactccac attcccaaaa aatcccagga actcctaaac cttcccctgt 3720gacagaagat gaggttggca gctgatcaga cctcaataat tttatactgt aataagctct 3780ttgaatgtgt atattattat tttttacaat catttcattt tgtatttaat atcaatggac 3840tgagtctgat tcagaaaata attgtaatgt tcatattcaa tatcttacag tgatacagtt 3900ttgtatttac atataaatat accgacatga tcaaaaccaa aaaaaaaaaa aaaaaa 3956793773DNAHomo sapiens 79aggcgcacag gtaccatttt gaccgtaaac atcctgccga tttgaaccga ggatttgggc 60ggcaggaaga gccgcggcgt aacggcagcc atcttgtttg tttgagtgaa tcggaaagga 120ggcgccggct gtggcggcgg cgggagctgc tcggaagcta cacctcgcaa gggctccccc 180ctttccccac cccctccccc gacccttttc ccctccccgg gccacccagc ccgcccaact 240cccagcggag agcaaggttt tcttctgttt tcatagccag ccagaacaat gttctacgca 300cattttgttc tcagtaaaag agggcctctg gccaaaattt ggctagcggc ccattgggat 360aagaagctaa ccaaagccca tgtgttcgag tgtaatttag agagcagcgt ggagagtatc 420atctcaccaa aggtgaaaat ggcattacgg acatcaggac atctcttact gggagtagtt 480cgaatctatc acaggaaagc caaatacctt cttgcagact gtaatgaagc attcattaag 540ataaagatgg cttttcggcc aggtgtggtt gacctgcctg aggaaaatcg ggaagcagct 600tataatgcca ttactttacc tgaagaattt catgactttg atcagccact gcctgactta 660gatgacatcg atgtggccca gcagttcagc ttgaatcaga gtagagtgga agagataacc 720atgagagaag aagttgggaa catcagtatt ttacaagaaa atgattttgg tgattttgga 780atggatgatc gtgagataat gagagaaggc agtgcttttg aggatgacga catgttagta 840agcactacta cttctaacct cctattagag tctgaacaga gcaccagcaa tctgaatgag 900aaaattaacc atttagaata tgaagatcaa tataaggatg ataattttgg agaaggaaat 960gatggtggaa tattagatga caaacttatt agtaataatg atggcggtat ctttgatgat 1020ccccctgccc tctctgaggc aggggtgatg ttgccagagc agcctgcaca tgacgatatg 1080gatgaggatg ataatgtatc aatgggtggg cctgatagtc ctgattcagt ggatcccgtt 1140gaaccaatgc caaccatgac tgatcaaaca acacttgttc caaatgagga agaagcattt 1200gcattggagc ctattgatat aactgttaaa gaaacaaaag ccaagaggaa gaggaagcta 1260attgttgaca gtgtcaaaga gttggatagc aagacaatta gagcccaact tagtgattat 1320tcagatattg ttactacttt ggatctggca ccgcccacca agaaattgat gatgtggaaa 1380gagacaggag gagtagaaaa actgttttct ttacctgctc agcctttgtg gaataacaga 1440ctactgaagc tctttacacg ctgtcttaca ccgcttgtac cagaagacct tagaaaaagg 1500aggaaaggag gagaggcaga taatttggat gaattcctca aagaatttga aaatccagag 1560gttcctagag aggaccagca acagcagcat cagcagcgtg atgttatcga tgagcccatt 1620attgaagagc caagccgcct ccaggagtca gtgatggagg ccagcagaac aaacatagat 1680gagtcagcta tgcctccacc accacctcag ggagttaagc gaaaagctgg acaaattgac 1740ccagagcctg tgatgcctcc tcagcaggta gagcagatgg aaataccacc tgtagagctt 1800cccccagaag aacctccaaa tatctgtcag ctaataccag agttagaact tctgccagaa 1860aaagagaagg agaaagagaa ggaaaaagaa gatgatgaag aggaagagga tgaagatgca 1920tcagggggcg atcaagatca ggaagaaaga agatggaaca aaaggactca gcagatgctt 1980catggtcttc agcgtgctct tgctaaaact ggagctgaat ctatcagttt gcttgagtta 2040tgtcgaaata cgaacagaaa acaagctgcc gcaaagttct acagcttctt ggttcttaaa 2100aagcagcaag ctattgagct gacacaggaa gaaccgtaca gtgacatcat cgcaacacct 2160ggaccaaggt tccatattat ataaggagct agaagcatta tagctagtgt ttgattcact 2220agtgcttaca aattgccccc atgtgtaggg gacacagaac cctttgagaa aacttagatt 2280tttgtctgta caaagtcttt gcctttttcc ttcttcattt ttttccagta cattaaattt 2340gtcaatttca tctttgaggg aaactgatta gatgggttgt gtttgtgttc tgatggagaa 2400aacagcaccc caaggactca gaagatgatt ttaacagttc agaacagatg tgtgcaatat 2460tggtgcatgt aataatgttg agtggcagtc aaaagtcatg atttttatct tagttcttca 2520ttactgcatt gaaaaggaaa acctgtctga gaaaatgcct gacagtttaa tttaaaacta 2580tggtgtaagt ctttgacaag aaaaaaaaac aaacaaacac ttctttccat cagtaacact 2640ggcaatcttc ctgttaacca ctctccttag ggatggtatc tgaaacaaca atggtcaccc 2700tcttgagatt cgttttaagt gtaattccat aatgagcaga ggtgtacgcg aaattgtgtt 2760atgactgata gccttcagct acaaaaagat aggactgacc tggtttaaag tgttctattt 2820tgtaaatcat tccatttgag tctttctgat gaacttggct atactgaaat ctgttatttt 2880agtgaggctc caaaatgagc aaagctaggc ctgattagag tagagtgact attaaaaaac 2940ataactttct aggagctata aatcaaagtt ttaaaaagat gtttggatat atttgagtat 3000tccgatcatg aaaacagaaa ttgccctgcc tactacaagg acagactgat gggaaattat 3060gcacctggtc aacttagctt ttaagcagac gatgctgtaa aaactaacgg cttctctgat 3120atttattgta agttttagta ctgatctcct tttccagtgc tgcacactcc tggtttggaa 3180ctttaatagc gttgcaacga aatcctatat ccagtttcct gtaatttaat tgaagaaaaa 3240tacatccaaa taaagacttt attattaaca gaccagatag catcagaaat catgtgactg 3300ttatgattat cagaatgtct taacttttta gggcaaagtt aacactgaaa gttctagctt 3360aagtgttgaa acttttgtgg gaaaaaaaaa tcacttttga aactcagact tcagtgtata 3420cccaataatt taaaattatg tgaaatgttt taaatttgtg aactcgtaat tactgtttta 3480atgattcagt ttcttcagag tggtaattgt ataaaattgc tattgcagct ttacattcaa 3540tatgatgtgc ctgtaaacca aggagttttc cccgtttgta aaaagacatt gtagataatt 3600gaatgtttga ttttagaaag gtcattagtt tcttgttaca cattttgtta gtctggtttt 3660tgttgcttat cgggtttaat attgttcttg aaaatagttg atgctatgtt atgtataact 3720tttctaataa aagttgtgtt ataagctgta aaaaaaaaaa aaaaaaaaaa aaa 3773806414DNAHomo sapiens 80gtgcgtgtgt ccctgtccgc gctgctgaaa cgggctcttc gagggatcgg cgtcacatga 60ctccgcctgc ccctcgccag cgcgcagatc gccagtccct cagtttgccc ggcaccggag 120gagggtcggg cggcatcttc cgggtactgg ggctctgcgg agcggagaag aggttccagc 180ggggaatggt atatctggat tcaagaagcc gcggctcggc gccagatcct ggagtgtaga 240tatttggggg gaggggagag ctagagggag cgagcgagcg agcgccagag agaggcagcg 300cgcagcgcgc acggacgggg ggctgctgcg cggagaagat gtaagcgcgt ggggtctcgc 360tggcctctga gcaccatgca gaaggggatc cggctgaatg atggccacgt cgcgtccctg 420ggactgctgg cgcgcaagga cggcacgcgc aaaggctacc tgagcaagcg gagttcggac 480aacacaaaat ggcaaaccaa gtggttcgcg ctgctgcaga acctgctctt ctacttcgag 540agcgactcga gctcgcggcc ctcggggctt tacctgctgg agggctgcgt ctgcgaccgc 600gcgccctccc ccaagccggc gctgtcggcc aaggagccgc tggagaaaca gcattacttc 660acggtgaact tcagccatga gaaccagaaa gccttggagc tgaggacaga ggacgcaaaa 720gattgtgacg aatgggtggc agccattgca catgccagct acaggaccct cgccacagag 780catgaggcat taatgcagaa atacctgcac ctgctgcaga tcgtggagac agagaagacc 840gtggccaagc agcttcggca gcagatcgag gatggggaga tcgagatcga gcggctgaag 900gcagagatca catccctgct caaggacaat gagcgcatcc agtccaccca gactgtcgcc 960cccaacgatg aagacagcga catcaagaaa attaagaagg tgcagagctt cctgcggggc 1020tggctgtgcc ggcggaagtg gaagaccatc atccaggact acatccggtc accccatgct 1080gacagcatgc gcaagaggaa ccaggtggtg ttcagcatgc tggaggctga ggctgagtac 1140gtgcagcagc tgcacatcct tgtcaacaat ttcctgcgcc cgctgcggat ggccgccagc 1200tccaagaagc ctcccatcac acacgacgac gtcagcagca tcttcctgaa cagcgaaacc 1260atcatgtttt tacatcagat cttttaccaa ggcctgaagg cccgcatctc cagctggccc 1320acgctggtcc tggctgacct atttgacatc ctgctgccca tgctcaacat ctaccaagag 1380ttcgtccgca accaccagta cagcctgcag atcctggccc actgcaagca gaaccgtgac 1440ttcgacaagc tgctgaagca ctacgaggcc aagcctgact gcgaggagag gacgctggag 1500accttcctca cctaccccat gttccagatc cccaggtaca tcctgaccct ccatgagctc 1560ctggcccaca cgcctcatga gcacgttgag cgcaacagcc tggactacgc caagtccaaa 1620ctggaggagc tgtccagaat aatgcacgat gaagtaagtg agacggagaa catccggaaa 1680aacctggcca tcgagcgcat gatcatcgaa ggctgtgaga tcctcctgga caccagccag 1740acctttgtga gacaaggttc cctcattcag gtgcccatgt ctgaaaaggg caagatcacc 1800agggggcgcc tggggtctct ctccctaaag aaagagggcg agcgacagtg cttcctgttt 1860tctaagcatc tgattatctg taccagaggc tctggaggga agcttcactt gaccaagaat 1920ggagtcatat ccctcattga ctgcacttta ttggaggagc cagaaagcac ggaggaggaa 1980gccaaaggat ccggccaaga catagatcac ttggatttta aaatcggggt ggagccaaag 2040gattccccgc cctttacagt catcctagtg gcctcgtcca gacaggagaa ggcagcgtgg 2100accagtgaca tcagccagtg tgtggataac atccgatgca atgggctcat gatgaacgca 2160tttgaagaaa attccaaggt cactgtgccg cagatgatca agaggaccag ggaggggacc 2220agggaagcag aaatgagcag gtccgacgcc tccttatatt gtgatgatgt tgacattcgc 2280ttcagcaaaa ccatgaactc ctgcaaagtg ctgcagatcc gctacgccag tgtggagcgg 2340ctgctggaga ggctgacgga cctgcgcttc ctgagcatcg acttcctcaa caccttcctg 2400cactcctacc gcgtcttcac caccgccatc gtggtcctgg acaagctcat taccatctac 2460aagaagccta tcagtgccat tcctgccagg tggctgaggt cgctggagct cctgtttgcc 2520agtggccaga acaataagct cctgtacggt gaacccccca agtccccgcg cgccacccgc 2580aagttctcct cgccgccacc tctgtccatc accaagacat cgtcaccgag ccgccggcgg 2640aagctctccc tgaacatccc catcatcact ggcggcaagg ccctggacct ggccgccctc 2700agctgcaact ccaatggcta caccagcatg tactcggcca tgtcaccctt cagcaaggcc 2760acgctggaca ccagcaagct ctatgtgtcc agcagcttca ccaacaagat tccagatgag 2820ggcgatacga cccctgagaa gcccgaagac ccttcagcgc tcagcaagca gagctcagaa 2880gtctccatga gagaggagtc agatattgat caaaaccaga gtgatgatgg tgatactgaa 2940acatcaccaa ctaaatctcc aacaacaccc aaatcagtca aaaacaaaaa ttcttcagag 3000ttcccactct tttcctataa caatggagtc gtcatgacct cctgtcgtga actggacaat 3060aaccgcagtg ccttgtcggc cgcctctgcc tttgccatag caaccgccgg ggccaacgag 3120ggcaccccaa acaaggagaa gtaccggagg atgtccttag ccagtgcagg gtttccccca 3180gaccagagga atggagacaa ggagtttgtg atccgcagag cagccaccaa tcgtgtcttg 3240aacgtgctcc gccactgggt gtccaagcac tctcaggact ttgagaccaa cgatgagctc 3300aaatgcaagg tgatcggctt cctggaagaa gtcatgcacg acccggagct cctgacccag 3360gagcggaagg ctgcagccaa catcatcagg actctgaccc aggaggaccc aggtgacaac 3420cagatcacgc tggaggagat cacgcagatg gctgaaggcg tgaaggctga gccctttgaa 3480aaccactcag ccctggagat cgcggagcag ctgaccctgc tagatcacct cgtcttcaag 3540aagattcctt atgaggagtt cttcggacaa ggatggatga aactggaaaa gaatgaaagg 3600accccttata tcatgaaaac cactaagcac ttcaatgaca tcagtaactt gattgcttca 3660gaaatcatcc gcaatgagga catcaacgcc agggtgagcg ccatcgagaa gtgggtggcc 3720gtagctgaca tatgccgctg cctccacaac tacaatgccg tactggagat cacctcgtcc 3780atgaaccgca gtgcaatctt ccggctcaaa aagacgtggc tcaaagtctc taagcagact 3840aaagctttga ttgataagct ccaaaagctt gtgtcatctg agggcagatt taagaatctc 3900agagaagctc tgaaaaattg tgacccaccc tgtgtccctt acctggggat gtacctcacc 3960gacctggcct tcatcgagga ggggacgccc aattacacgg aagacggcct ggtcaacttc 4020tccaagatga ggatgatatc ccatattatc cgagagattc gccagtttca acaaactgcc 4080tacaaaatag agcaccaagc aaaggtaacg caatatttac tggaccaatc ttttgtaatg 4140gatgaagaaa gcctctacga gtcttctctc cgaatagaac caaaactccc cacctgaagc 4200tgagcccagc ccagacccag ctgctcccgg ggacatgtgc tagatgatac tgtacatatt 4260cgtttggttt cactggattt tcttcttcag tatgtgcttc tccaagaata caaatcgtcc 4320ttgttcttag attcctgtag aaccggaata tgaatttctg caccgtttca gacttcgccc 4380acccatccct cccctcgtct cctgcagtgc ctgtttcttt taaacagctg tactcttggt 4440ccctcttccc tagactcctc actcttctca gaggggaaac agcacccttg catacaagaa 4500tcttagactc cagtcctgct tccgtccctc cccagcccag gctcctgggt tgaggtggcc 4560acccaggcat cctcccagca tgttccatgt agttgttata actgggtggg gggtgggggg 4620cggcgggagg gggaaaccat accctgaagt ccagtcattg acaaatcttc ccgctgatgg 4680tgatgtcaat ttccaaagca gcttctccag ccaaaatcgc aggtctcaaa actccccatg 4740tgtctcccag taacctggac ggaagggagt cctctctgct cagaaccaca cccctcgtac 4800caatgctgcc atctcgttca ggccccacgt cgctccttgc tctaggatta acaccagata 4860gcatgaatag cagtctcaat acaactggat gaggccctag acttcccgag gaaatggagt 4920cacaaacacc aagccacgtc gactcttgcc gaccactggc ccagcatcca ctgaaagtcg 4980ggaacacaaa aatgtcactt ttcctcttta agctgcctaa cggtcactac aagcttacat 5040tgagatgctc taagtctgta taccttgtga taattagtac cacactgtag aattaggaaa 5100tcaataacca agtgttttta ttgcatatac tgtagtcctg tctaaatgcc ttctagcagg 5160aatatagtaa tgtagtgctt attctgtgaa tattaccatg tattttttac actgtacagt 5220atagaaaaca caggttaact ccgaagtggc aggcatgctc cactacaaca gacagacaac 5280ttttgctgta agcaatacct agtggtatga gaattctatt tcaagtccta aaatatttca 5340acttacagct tgtttggaaa aaaatttcca tttttgtaaa aatatatgtt tcctgattac 5400ctcttgctaa taaatctatt ctatctcagg gtgaacagcg agttttgatg ggtttcattc 5460gttcagtcaa ggaatatttg atgagcactt gctccttacc cagcccagcc tgggaccgga 5520gatccagagt gtcaaggaca ccatacctgc tttttaggca ccaacagttt ggtggggaag 5580actgtttcag ttgcctattg caccaagaac aagccactcc aaaacataat ggcttaaaac 5640catttttgtt acctttcaca gttctatggg ttgactgggt ccagctgtca gttcttattt 5700ggagtctctc atgaagtttc agtcactcag caactgggac tggagtcatc tgaaggctca 5760actggaccgg gtggtgctct agttggtgca ccaagatggc gctgtcacat ggctggatgt 5820tgatgtctgc tgggctgcac tggggctgtt catgggagca tccacacgtg gcctctctgt 5880gtggcttggg ctcctcacag tccggaagct gggttccaag agcgactgtt ccagcagcct 5940caggcagaag ctacaaggct gcccagatgc catcctgccc agatgtgtcc tcactgtcac 6000ccaggaaggg aagccccgga acaccaccct cagtcacagg catggggccc actgcaaggc 6060acaacccact ccagagctcc caaggccgcc tcccctggga cctgcagcca gctggctcca 6120taactgcttt tccgtttcct

ccaggcattt tcatcctagc cctactttgt gctgggatct 6180gagggggata gcaagcggag aaagaaggga tctagaggga gaagattcta gatccttctt 6240ttgactgcca gctgattttg attgccagct ttacctgctt catgagctca gccaagtcac 6300ttaacctctc agagcttcac tgttctcatc tgaaaaatgg ggatgaaaat ggtatctcat 6360tacagagtag aattaaatga attattataa ttaaaaaaaa aaaaaaaaaa aaaa 6414811554DNAHomo sapiens 81ggggaggggg cagtgtcctc cgagccagga caggcatgtt gttgggactg gcggccatgg 60agctgaaggt gtgggtggat ggcatccagc gtgtggtctg tggggtctca gagcagacca 120cctgccagga agtggtcatc gcactagccc aagcaatagg ccagactggc cgctttgtgc 180ttgtgcagcg gcttcgggag aaggagcggc agttgctgcc acaagagtgt ccagtgggcg 240cccaggccac ctgcggacag tttgccagcg atgtccagtt tgtcctgagg cgcacagggc 300ccagcctagc tgggaggccc tcctcagaca gctgtccacc cccggaacgc tgcctaattc 360gtgccagcct ccctgtaaag ccacgggctg cgctgggctg tgagccccgc aaaacactga 420cccccgagcc agcccccagc ctctcacgcc ctgggcctgc ggcccctgtg acacccacac 480caggctgctg cacagacctg cggggcctgg agctcagggt gcagaggaat gctgaggagc 540tgggccatga ggccttctgg gagcaagagc tgcgccggga gcaggcccgg gagcgagagg 600gacaggcacg cctgcaggca ctaagtgcgg ccactgctga gcatgccgcc cggctgcagg 660ccctggacgc tcaggcccgt gccctggagg ctgagctgca gctggcagcg gaggcccctg 720ggcccccctc acctatggca tctgccactg agcgcctgca ccaggacctg gctgttcagg 780agcggcagag tgcggaggtg cagggcagcc tggctctggt gagccgggcc ctggaggcag 840cagagcgagc cttgcaggct caggctcagg agctggagga gctgaaccga gagctccgtc 900agtgcaacct gcagcagttc atccagcaga ccggggctgc gctgccaccg cccccacggc 960ctgacagggg ccctcctggc actcagggcc ctctgcctcc agccagagag gagtccctcc 1020tgggcgctcc ctctgagtcc catgctggtg cccagcctag gccccgaggt ggcccccatg 1080acgcagaact cctggaggta gcagcagctc ctgccccaga gtggtgtcct ctggcagccc 1140agccccaggc tctgtgacag cctagtgagg gctgcaagac catcctgccc ggaccacaga 1200aggagagttg gcggtcacag agggctcctc tgccaggcag tgggaagccc tgggtttggc 1260ctcaggagct gggggtgcag tgggggactg ccctagtcct tgccaggtcg ccagcaccct 1320ggagaagcat ggggcgtagc cagctcggaa cttgccaggc cccaaaggcc acgactgcct 1380gttggggaca ggagatgcat ggacagtgtg ctcaagctgt gggcatgtgc ttgcctgcgg 1440gagaggtcct tcactgtgtg tacacagcaa gagcatgtgt gtgccacttc ccctacccca 1500acgtgaaaac ctcaataaac tgcccgaagc agcttgaaaa aaaaaaaaaa aaaa 1554824751DNAHomo sapiens 82agagccaccg cggagcgcgc gcggggttgg ttgccgcgag cgtgggggag cgtggaccgc 60ggcgctgctc agcggtgggg ctgccttccc ccggccctcc tccctggtcc ctggcgaggg 120cactggcggc ggcggggccg gggtccgcaa ggccggagaa ggccgccggg cccgggcatg 180gtggtctggg gcaacgcgga agaagctcca ccatgaggcg aggtggatgg aggaagcgag 240ctgaaaatga tggctgggaa acatggggtg ggtatatggc tgccaaggtc cagaaattgg 300aggaacagtt tcgatcagat gctgctatgc agaaggatgg gacttcatct acaattttta 360gtggagttgc catctatgtt aatggataca cagatccttc cgctgaggaa ttgagaaaac 420taatgatgtt gcatggaggt caataccatg tatattattc cagatctaaa acaacacata 480ttattgccac aaatcttccc aatgccaaaa ttaaagaatt aaagggggaa aaagtaattc 540gaccagaatg gattgtggaa agcatcaaag ctggacgact cctctcctac attccatatc 600agctgtacac caagcagtcc agtgtgcaga aaggtctcag ctttaatcct gtatgcagac 660ctgaggatcc tctgccaggt ccaagcaata tagccaaaca gctcaacaac agggtaaatc 720acatcgttaa gaagattgaa acggaaaatg aagtcaaagt caatggcatg aacagttgga 780atgaagaaga tgaaaataat gattttagtt ttgtggatct ggagcagacc tctccgggaa 840ggaaacagaa tggaattccg catcccagag ggagcactgc catttttaat ggacacactc 900ctagctctaa tggtgcctta aagacacagg attgcttggt gcccatggtc aacagtgttg 960ccagcaggct ttctccagcc ttttcccagg aggaggataa ggctgagaag agcagcactg 1020atttcagaga ctgcactctg cagcagttgc agcaaagcac cagaaacaca gatgctttgc 1080ggaatccaca cagaactaat tctttctcat tatcaccttt gcacagtaac actaaaatca 1140atggtgctca ccactccact gttcaggggc cttcaagcac aaaaagcact tcttcagtat 1200ctacgtttag caaggcagca ccttcagtgc catccaaacc ttcagactgc aattttattt 1260caaacttcta ttctcattca agactgcatc acatatcaat gtggaagtgt gaattgactg 1320agtttgtcaa taccctacaa agacaaagta atggtatctt tccaggaagg gaaaagttaa 1380aaaaaatgaa aacaggcagg tctgcacttg ttgtaactga cacaggagat atgtcagtat 1440tgaattctcc cagacatcag agctgtataa tgcatgttga tatggattgc ttctttgtat 1500cagtgggtat acgaaataga ccagatctca aaggaaaacc agtggctgtt acaagtaaca 1560gaggcacagg aagggcacct ttacgtcctg gcgctaaccc ccagctggag tggcagtatt 1620accagaataa aatcctgaaa ggcaaagcag cagatatacc agattcatca ttgtgggaga 1680atccagattc tgcgcaagca aatggaattg attctgtttt gtcaagggct gaaattgcat 1740cttgtagtta tgaggccagg caacttggca ttaagaacgg aatgtttttt gggcatgcta 1800aacaactatg tcctaatctt caagctgttc catacgattt tcatgcatat aaggaagtcg 1860cacaaacatt gtatgaaaca ttggcaagct acactcataa cattgaagct gtcagttgtg 1920atgaagcgct ggtagacatt accgaaatcc ttgcagagac caaacttact cctgatgaat 1980ttgcaaatgc tgttcgtatg gaaatcaaag accagacgaa atgtgctgcc tctgttggaa 2040ttggttctaa tattctcctg gctagaatgg caactagaaa agcaaaacca gatgggcagt 2100accacctaaa accagaagaa gtagatgatt ttatcagagg ccagctagtg accaatctac 2160caggagttgg acattcaatg gaatctaagt tggcatcttt gggaattaaa acttgtggag 2220acttgcagta tatgaccatg gcaaaactcc aaaaagaatt tggtcccaaa acaggtcaga 2280tgctttatag gttctgccgt ggcttggatg atagaccagt tcgaactgaa aaggaaagaa 2340aatctgtttc agctgagatc aactatggaa taaggtttac tcagccaaaa gaggcagaag 2400cttttcttct gagtctttca gaagaaattc aaagaagact agaagccact ggcatgaagg 2460gtaaacgtct aactctcaaa atcatggtac gaaagcctgg ggctcctgta gaaactgcaa 2520aatttggagg ccatggaatt tgtgataaca ttgccaggac tgtaactctt gaccaggcaa 2580cagataatgc aaaaataatt ggaaaggcga tgctaaacat gtttcataca atgaaactaa 2640atatatcaga tatgagaggg gttgggattc acgtgaatca gttggttcca actaatctga 2700acccttccac atgtcccagt cgcccatcag ttcagtcaag ccactttcct agtgggtcat 2760actctgtccg tgatgtcttc caagttcaga aagctaagaa atccaccgaa gaggagcaca 2820aagaagtatt tcgggctgct gtggatctgg aaatatcatc tgcttctaga acttgcactt 2880tcttgccacc ttttcctgca catctgccga ccagtcctga tactaacaag gctgagtctt 2940cagggaaatg gaatggtcta catactcctg tcagtgtgca gtcgagactt aacctgagta 3000tagaggtccc gtcaccttcc cagctggatc agtctgtttt agaagcactt ccacctgatc 3060tccgggaaca agtagagcaa gtctgtgctg tccagcaagc agagtcacat ggcgacaaaa 3120agaaagaacc agtaaatggc tgtaatacag gaattttgcc acaaccagtt gggacagtct 3180tgttgcaaat accagaacct caagaatcga acagtgacgc aggaataaat ttaatagccc 3240ttccagcatt ttcacaggtg gaccctgagg tatttgctgc ccttcctgct gaacttcaga 3300gggagctgaa agcagcgtat gatcaaagac aaaggcaggg cgagaacagc actcaccagc 3360agtcagccag cgcatctgtg ccaaagaatc ctttacttca tctaaaggca gcagtgaaag 3420aaaagaaaag aaacaagaag aaaaaaacca ttggttcacc aaaaaggatt cagagtcctt 3480tgaataacaa gctgcttaac agtcctgcaa aaactctgcc aggggcctgt ggcagtcccc 3540agaagttaat tgatgggttt ctaaaacatg aaggacctcc tgcagagaaa cccctggaag 3600aactctctgc ttctacttca ggtgtgccag gcctttctag tttgcagtct gacccagctg 3660gctgtgtgag acctccagca cccaatctag ctggagctgt tgaattcaat gatgtgaaga 3720ccttgctcag agaatggata actacaattt cagatccaat ggaagaagac attctccaag 3780ttgtgaaata ctgtactgat ctaatagaag aaaaagattt ggaaaaactg gatctagtta 3840taaaatacat gaaaaggctg atgcagcaat cggtggaatc ggtttggaat atggcatttg 3900actttattct tgacaatgtc caggtggttt tacaacaaac ttatggaagc acattaaaag 3960ttacataaat attaccagag agcctgatgc tctctgatag ctgtgccata agtgcttgtg 4020aggtatttgc aaagtgcatg atagtaatgc tcggagtttt tataatttta aatttctttt 4080aaagcaagtg ttttgtacat ttcttttcaa aaagtgccaa atttgtcagt attgcatgta 4140aataattgtg ttaattattt tactgtagca tagattctat ttacaaaatg tttgtttata 4200aagttttatg gatttttaca gtgaagtgtt tacagttgtt taataaagaa ctgtatgtat 4260attttgtaca ggctcctttt tgtgaatcct taaaaactca actctaggaa gcaactactg 4320tttattatac taaaaggctg aaaaacctcc aggccagact gctaagctct gaaattcctg 4380agaggtctca gaccgggatt ctacttgttc caagaaaggg taaagcttct aaaccatctt 4440attcttgtct ccaagcatga acacaggagc atgttaagaa aatctttact acttcttcca 4500tgcggagaaa tctacatatt ttgaattaga aacaccctca cacccacttg aagatttttt 4560tcctgggaac attatgtccc gtagatcaga ggtggtgttg tctttttgct tctactggcc 4620attgagaaac tttgatgata aaaaagaacg gtatagattt ttcaaacgta tataaaatat 4680ttttatgtta tatgttatgc cataacttta aaataaaaat agtttaaaat tctaaaaaaa 4740aaaaaaaaaa a 4751832667DNAHomo sapiens 83ctctccgccc cgccccggct cgggcggccg gaggacccgg agctaaggcg cccgaacccg 60cggcggcggt ggggacgatg tggttctttg cccgggaccc ggtccgggac tttccgttcg 120agctcatccc ggagccccca gagggcggcc tgcccgggcc ctgggccctg caccgcggcc 180gcaagaaggc cacaggcagc cccgtgtcca tcttcgtcta tgatgtgaag cctggcgcgg 240aagagcagac ccaggtggcc aaagctgcct tcaagcgctt caaaactcta cggcacccca 300acatcctggc ttacatcgat ggactggaga cagaaaaatg cctccacgtc gtgacagagg 360ctgtgacccc gttgggaata tacctcaagg cgagagtgga ggctggtggc ctgaaggagc 420tggagatctc ctgggggcta caccagatcg tgaaagccct cagcttcctg gtcaacgact 480gcagcctcat ccacaacaat gtctgcatgg ccgccgtgtt cgtggaccga gctggcgagt 540ggaagcttgg gggcctggac tacatgtatt cggcccaggg caacggtggg ggacctcccc 600gcaaggggat ccccgagctt gagcagtatg accccccgga gttggctgac agcagtggca 660gagtggtcag agagaagtgg tcagcagaca tgtggcgctt gggctgcctc atttgggaag 720tcttcaatgg gcccctacct cgggcagcag ccctacgcaa ccctgggaag atccccaaaa 780cgctggtgcc ccattactgt gagctggtgg gagcaaaccc caaggtgcgt cccaacccag 840cccgcttcct gcagaactgc cgggcacctg gtggcttcat gagcaaccgc tttgtagaaa 900ccaacctctt cctggaggag attcagatca aagagccagc cgagaagcaa aaattcttcc 960aggagctgag caagagcctg gacgcattcc ctgaggattt ctgtcggcac aaggtgctgc 1020cccagctgct gaccgccttc gagttcggca atgctggggc cgttgtcctc acgcccctct 1080tcaaggtggg caagttcctg agcgctgagg agtatcagca gaagatcatc cctgtggtgg 1140tcaagatgtt ctcatccact gaccgggcca tgcgcatccg cctcctgcag cagatggagc 1200agttcatcca gtaccttgac gagccaacag tcaacaccca gatcttcccc cacgtcgtac 1260atggcttcct ggacaccaac cctgccatcc gggagcagac ggtcaagtcc atgctgctcc 1320tggccccaaa gctgaacgag gccaacctca atgtggagct gatgaagcac tttgcacggc 1380tacaggccaa ggatgaacag ggccccatcc gctgcaacac cacagtctgc ctgggcaaaa 1440tcggctccta cctcagtgct agcaccagac acagggtcct tacctctgcc ttcagccgag 1500ccactaggga cccgtttgca ccgtcccggg ttgcgggtgt cctgggcttt gctgccaccc 1560acaacctcta ctcaatgaac gactgtgccc agaagatcct gcctgtgctc tgcggtctca 1620ctgtagatcc tgagaaatcc gtgcgagacc aggccttcaa ggccattcgg agcttcctgt 1680ccaaattgga gtctgtgtcg gaggacccga cccagctgga ggaagtggag aaggatgtcc 1740atgcagcctc cagccctggc atgggaggag ccgcagctag ctgggcaggc tgggccgtga 1800ccggggtctc ctcactcacc tccaagctga tccgttcgca cccaaccact gccccaacag 1860aaaccaacat tccccaaaga cccacgcctg aaggagttcc tgccccagcc cccacccctg 1920ttcctgccac ccctacaacc tcaggccact gggagacgca ggaggaggac aaggacacag 1980cagaggacag cagcactgct gacagatggg acgacgaaga ctggggcagc ctggagcagg 2040aggccgagtc tgtgctggcc cagcaggacg actggagcac cgggggccaa gtgagccgtg 2100ctagtcaggt cagcaactcc gaccacaaat cctccaaatc cccagagtcc gactggagca 2160gctgggaagc tgagggctcc tgggaacagg gctggcagga gccaagctcc caggagccac 2220ctcctgacgg tacacggctg gccagcgagt ataactgggg tggcccagag tccagcgaca 2280agggcgaccc cttcgctacc ctgtctgcac gtcccagcac ccagccgagg ccagactctt 2340ggggtgagga caactgggag ggcctcgaga ctgacagtcg acaggtcaag gctgagctgg 2400cccggaagaa gcgcgaggag cggcggcggg agatggaggc caaacgcgcc gagaggaagg 2460tggccaaggg ccccatgaag ctgggagccc ggaagctgga ctgaaccgtg gcggtggccc 2520ttcccggctg cggagagccc gccccacaga tgtatttatt gtacaaacca tgtgagcccg 2580gccggcccag ccaggccatc tcacgtgtac ataatcagag ccacaataaa ttctatttca 2640caccccttga aaaaaaaaaa aaaaaaa 2667842615DNAHomo sapiens 84actcgccgca gcctgcgcgc cttctccagt ccgcggtgcc atggcccccg cccgtctgtt 60cgcgctgctg ctgttcttcg taggcggagt cgccgagtcg atccgagaga ctgaggtcat 120cgacccccag gacctcctag aaggccgata cttctccgga gccctaccag acgatgagga 180tgtagtgggg cccgggcagg aatctgatga ctttgagctg tctggctctg gagatctgga 240tgacttggaa gactccatga tcggccctga agttgtccat cccttggtgc ctctagataa 300ccatatccct gagagggcag ggtctgggag ccaagtcccc accgaaccca agaaactaga 360ggagaatgag gttatcccca agagaatctc acccgttgaa gagagtgagg atgtgtccaa 420caaggtgtca atgtccagca ctgtgcaggg cagcaacatc tttgagagaa cggaggtcct 480ggcagctctg attgtgggtg gcatcgtggg catcctcttt gccgtcttcc tgatcctact 540gctcatgtac cgtatgaaga agaaggatga aggcagctat gacctgggca agaaacccat 600ctacaagaaa gcccccacca atgagttcta cgcgtgaagc ttgcttgtgg gcactggctt 660ggactttagc ggggagggaa gccaggggat tttgaagggt ggacattagg gtagggtgag 720gtcaacctaa tactgacttg tcagtatctc cagctctgat tacctttgaa gtgttcagaa 780gagacattgt cttctactgt tctgccaggt tcttcttgag ctttgggcct cagttgccct 840ggcagaaaaa tggattcaac ttggcctttc tgaaggcaag actgggattg gatcacttct 900taaacttcca gttaagaatc taggtccgcc ctcaagccca tactgaccat gcctcatcca 960gagctcctct gaagccaggg ggctaacgga tgttgtgtgg agtcctggct ggaggtcctc 1020ccccagtggc cttcctccct tcctttcaca gccggtctct ctgccaggaa atgggggaag 1080gaactagaac cacctgcacc ttgagatgtt tctgtaaatg ggtacttgtg atcacactac 1140gggaatctct gtggtatata cctggggcca ttctaggctc tttcaagtga cttttggaaa 1200tcaacctttt ttatttgggg gggaggatgg ggaaaagagc tgagagttta tgctgaaatg 1260gatttataga atatttgtaa atctattttt agtgtttgtt cgttttttta actgttcatt 1320cctttgtgca gagtgtatat ctctgcctgg gcaagagtgt ggaggtgccg aggtgtcttc 1380attctctcgc acatttccac agcacctgct aagtttgtat ttaatggttt ttgtttttgt 1440ttttgtttgt ttcttgaaaa tgagagaaga gccggagaga tgatttttat taattttttt 1500tttttttttt tttttttact atttatagct ttagataggg cctcccttcc cctcttcttt 1560ctttgttctc tttcattaaa ccccttcccc agtttttttt ttatacttta aaccccgctc 1620ctcatggcct tggccctttc tgaagctgct tcctcttata aaatagcttt tgccgaaaca 1680tagttttttt ttagcagatc ccaaaatata atgaagggga tggtgggata tttgtgtctg 1740tgttcttata atatattatt attcttcctt ggttctagaa aaatagataa atatattttt 1800ttcaggaaat agtgtggtgt ttccagtttg atgttgctgg gtggttgagt gagtgaattt 1860tcatgtggct gggtgggttt ttgccttttt ctcttgccct gttcctggtg ccttctgatg 1920gggctggaat agttgaggtg gatggttcta ccctttctgc cttctgtttg ggacccagct 1980ggtgttcttt ggtttgcttt cttcaggctc tagggctgtg ctatccaata cagtaaccac 2040atgcggctgt ttaaagttaa gccaattaaa atcacataag attaaaaatt ccttcctcag 2100ttgcactaac cacgtttcta gaggcgtcac tgtatgtagt tcatggctac tgtactgaca 2160gcgagagcat gtccatctgt tggacagcac tattctagag aactaaactg gcttaacgag 2220tcacagcctc agctgtgctg ggacgaccct tgtctccctg ggtagggggg ggggaatggg 2280ggagggctga tgaggcccca gctggggcct gttgtctggg accctccctc tcctgagagg 2340ggaggcctgg tggcttagcc tgggcaggtc gtgtctcctc ctgaccccag tggctgcggt 2400gaggggaacc accctccctt gctgcaccag tggccattag ctcccgtcac cactgcaacc 2460cagggtccca gctggctggg tcctcttctg cccccagtgc ccttcccctt gggctgtgtt 2520ggagtgagca cctcctctgt aggcacctct cacactgttg tctgttactg attttttttg 2580ataaaaagat aataaaacct ggtactttct aaaaa 2615854766DNAHomo sapiens 85tttttttttt tttttttttt tttttcgcaa tttccactcg cggggagcag gaaacccggc 60gcagccgggc gcattgggcc gcgatgcaac agcagcagca ggagtcgccc cggggcagca 120gcggcagcag cagcagaggc agcagcgggc ggcgctgagc cgccgccgcc gccactgagg 180aagaagccgg cccagccgcc gccgcgtccg gaccctcgcg cctggatccc agcgccccga 240tcccggcgcc ccaaccccca cgcccgcctc cgccaacttt cacgctgcct cggcggcccg 300gcccggctcg acgccaatgg tggaggccat agtggagttt gactaccagg cccagcacga 360tgatgagctg acgatcagcg tgggtgaaat catcaccaac atcaggaagg aggatggagg 420ctggtgggag ggacagatca acggcaggag aggtttgttc cctgacaact ttgtaagaga 480aataaagaaa gagatgaaga aagaccctct caccaacaaa gctccagaaa agcccctgca 540cgaagtgccc agtggaaact ctttgctgtc ttctgaaacg attttaagaa ccaataagag 600aggcgagcga cggaggcgcc ggtgccaggt ggcattcagc tacctgcccc agaatgacga 660tgaacttgag ctgaaagttg gcgacatcat agaggtggta ggagaggtag aggaaggatg 720gtgggaaggt gttctcaacg ggaagactgg aatgtttcct tccaacttca tcaaggagct 780gtcaggggag tcggatgagc ttggcatttc ccaggatgag cagctatcca agtcaagttt 840aagggaaacc acaggctccg agagtgatgg gggtgactca agcagcacca agtctgaagg 900tgccaacggg acagtggcaa ctgcagcaat ccagcccaag aaagttaagg gagtgggctt 960tggagacatt ttcaaagaca agccaatcaa actaagacca aggtcaattg aagtagaaaa 1020tgactttctg ccggtagaaa agactattgg gaagaagtta cctgcaacta cagcaactcc 1080agactcatca aaaacagaaa tggacagcag gacaaagagc aaggattact gcaaagtaat 1140atttccatat gaggcacaga atgatgatga attgacaatc aaagaaggag atatagtcac 1200tctcatcaat aaggactgca tcgacgtagg ctggtgggaa ggagagctga acggcagacg 1260aggcgtgttc cccgataact tcgtgaagtt acttccaccg gactttgaaa aggaagggaa 1320tagacccaag aagccaccgc ctccatccgc tcctgtcatc aaacaagggg caggcaccac 1380tgagagaaaa catgaaatta aaaagatacc tcctgaaaga ccagaaatgc ttccaaacag 1440aacagaagaa aaagaaagac cagagagaga gccaaaactg gatttacaga agccctccgt 1500tcctgccata ccgccaaaaa agcctcggcc acctaagacc aattctctca gcagacctgg 1560cgcactgccc ccgagaaggc cggagagacc ggtgggtccg ctgacacaca ccaggggtga 1620cagtccaaag attgacttgg ccggcagttc gctatctggc atcctggaca aagatctctc 1680ggaccgcagc aatgacattg acttagaagg ttttgactcc gtggtatcat ctactgagaa 1740actcagtcat ccgaccacaa gcagaccaaa agctacaggg aggcggcctc cgtcccagtc 1800cctcacatct tcatcccttt caagccctga tatcttcgac tccccaagtc ccgaagagga 1860taaggaggaa cacatttcac ttgcgcacag aggagtggac gcgtcaaaga aaacttccaa 1920gactgttacc atatcccaag tgtctgacaa caaagcatcc ctgccgccca agccggggac 1980catggcagca ggtggcggtg ggccagcccc tctgtcctca gcggcgccct cccccctgtc 2040atcctctttg ggaacagctg gacacagagc caactccccg tctctgttcg gcacggaagg 2100aaaaccaaag atggagcctg cggccagcag ccaggcggcc gtggaggagc taaggacaca 2160ggtccgcgag ctgaggagca tcatcgagac catgaaggac cagcagaaac gagagattaa 2220acagttattg tctgagttgg atgaagagaa gaaaatccgg cttcggttgc agatggaagt 2280gaacgacata aagaaagctc tacaatcaaa atgaatactt gatcaatgaa atgtcacatt 2340attcatcctg agtccgagac tcaaattttc tgccccagcc aaaataatct tgtgccaaaa 2400gattaaaggt ttgcctcaaa atgtccctgt ttgaaagatt agcacaaaag tcttgatagc 2460acaacacaaa ttccatccaa gaggagaatc ttccccaggg tttagtcctg gggctggcac 2520tcgttgtgac ttacacagag caaaattgtg ctaaaggctt ttctactctg agatctcaat 2580gcgaaatgaa aactcaggca gtttagtcca tagtggtact attttgatga tattttccat 2640taataaaatg taatttcaga ttattcgttt acaagcttta taattttatg attttttaat 2700cgtgttttgt cacagacttc cctagtgttt gtactacacg tagtcagaag cgagtgtcct 2760tttcttttgc ttcaggctaa gagctgcctc gctctttgtc cccccattag gattctatta 2820catatgcaat tgtaggttca acctgtccct ttccctgcca gcaaacccca ccaccctaag 2880agaaatttta gcttatatat gacggtatat ttacaaaaag agaaagagaa aatctggtat 2940ttgcaatgat ctgtgccttc tttttaccac cctcttgatt

ggagcttttg tgatgcagct 3000accatgattc aaaaaaatta aaaattaaaa aaaaaaaatc tgccacttat ccaagtccac 3060tagaggccac tgtcttcaaa gcttctctca ccctagccaa aggtcctaag aggagacagc 3120tgtgaagttg ggcgtgctct gtggtaccag ctgtgacttt tctatttctc ctagttttag 3180gttgttcatg aaactagaaa tgtcatcctg cttgattttt catcagccaa gttaaacccc 3240tgctttctgt cctttgcacc ttttgcgtga acagaatatg cattattaaa gcaaaaataa 3300ataaaagtaa aatgcaaatg aaaacaaggg agggaaagtt gtattatttc ctgcactggg 3360ttacccgtgt gtgttatcgt ttaaactgta ttcacataat gtcatttgcc ttgctcactt 3420gtaacccctt cctcaggtcc aagagaatgg gaggagggtc atgttgaagt gtagccactg 3480gaactttctt gcatttatgg agttgctttt tctttcccaa ggaaactgat gtttgcctgt 3540ccgctttatc tttgtagtac atgaacagtt cagccttaga ctatgtaact gttttctcat 3600ccttagctga aaatgagggg cctactgtat tgcgagactg ttcaggggta ggggtggagg 3660gggtggtccc ttaatggccc ctgaagatgt tggatgtgtt tctcaaaagc tgctttgtct 3720ctttcctgag tttaatagtg aaactactaa acattaatag atttgcacag ccacaaagaa 3780tgagagttga taataccgaa gaagtgatgc aaaaacaaaa aatcacatta ctgatcattg 3840atagtattac aaataaatgt ctcttccttt ctcttcctcc cttcctcccc ctgccttcct 3900cttaacctat gtgctcatcc ttgctacttg aggctgttat ttccctccga gtatttaagg 3960agcccaaaca ccttggtctt cctgggtggg ggcataatta agggaaggga gtgtataagg 4020aaggaaacct cataccctcc attcccatcc ctggatatat tgccttttca gcagcctcgg 4080gttcagtgtg cttggggtca ggagtgccag gttcccaaga gcagcgtaaa acatccctgt 4140accccttgac agttataagc atttctgcgt taaacttgaa gattccagag attccccacg 4200acctaatgat ctaagaatgc agattggatt ctttgatgtt caaatttctc atttacttat 4260gaaaatccct aattatatag ttttatataa tgtgtataca gagtaggatt gttgatgaaa 4320ttgagcggtt ggaacaccct catggaacac tggcaacatg gaatgtagag agctgatgtc 4380ttccccctca tagaggccat tggcttcctt tgtataagga gagggagaag tgattctgga 4440aggagaagtt ggtatgtcta gcttcattgc ggcccctcgg gctacccagc aagaggattc 4500tgcatcaagg aactggacga gccgctaccc aaactgccac catctttact ctttacaaaa 4560tggacccatc gagaatgttg aaaagcttgg aagtatcact tttgaaaaaa aaaaaaatta 4620ttttgcattc agcatggact cgaccaggca tctatggaga ttattttttt gcttcatttt 4680ataaagttgt atttagaaaa gtcttaagta ttgtgctttg taaagaagat gattaaaatg 4740aaattttgtg agaatagttt tgttca 4766864611DNAHomo sapiens 86ccccgtctgc gtccgcgttc gcggctcccg tttgcatcat ctccagccgg cggctgctcc 60agggaggctg ggcgcgatcc tctccgcccg cggctccaac ccgcactctg cgcctctcct 120cgcctttctc gcacctgctc ctgcgccagg cccggagacc cccggggcgg cttcccagaa 180cctgcggagc acaactggcc gaccgaccca ttcattggga accccgtctt ttgccagagc 240ccacgtcccc tgccacctct agctcggagc ggcgtgtagc gccatggaga agagcaacga 300gaccaacggc taccttgaca gcgctcaggc ggggcctgcg gccgggcccg gagctccggg 360gaccgcggcg ggacgcgcac ggcgttgcgc gggcttcctg cggcgccaag cgctggtgct 420gctcaccgtg tccggggtgc tggcgggcgc gggcctgggc gcggcgttgc gcgggctcag 480cctgagccgc acgcaggtca cctacctggc cttccccggc gagatgctgc tccgcatgct 540gcgcatgatc atcctgccgc tggtggtctg cagcctggtg tcgggcgccg cctcgctcga 600tgccagctgc ctcgggcgtc tgggcggcat cgctgtcgcc tactttggcc tcaccacact 660gagtgcctcg gcgctcgccg tggccttggc gttcatcatc aagccaggat ccggtgcgca 720gacccttcag tccagcgacc tggggctgga ggactcgggg cctcctcctg tccccaaaga 780gacggtggac tctttcctcg acctggccag aaacctgttt ccctccaatc ttgtggttgc 840agctttccgt acgtatgcaa ccgattataa agtcgtgacc cagaacagca gctctggaaa 900tgtaacccat gaaaagatcc ccataggcac tgagatagaa gggatgaaca ttttaggatt 960ggtcctgttt gctctggtgt taggagtggc cttaaagaaa ctaggctccg aaggagaaga 1020cctcatccgt ttcttcaatt ccctcaacga ggcgacgatg gtgctggtgt cctggattat 1080gtggtacgta cctgtgggca tcatgttcct tgttggaagc aagatcgtgg aaatgaaaga 1140catcatcgtg ctggtgacca gcctggggaa atacatcttc gcatctatat tgggccatgt 1200tattcatgga ggaattgttc tgccacttat ttattttgtt ttcacacgaa aaaacccatt 1260cagattcctc ctgggcctcc tcgccccatt tgcgacagca tttgctacct gctccagctc 1320agcgaccctt ccctctatga tgaagtgcat tgaagagaac aatggtgtgg acaagaggat 1380cagcaggttt attctcccca tcggggccac cgtgaacatg gacggagcag ccatcttcca 1440gtgtgtggcc gcggtgttca ttgcgcaact caacaacgta gagctcaacg caggacagat 1500tttcaccatt ctagtgactg ccacagcgtc cagtgttgga gcagcaggcg tgccagctgg 1560aggggtcctc accattgcca ttatcctgga ggccattggg ctgcctactc atgacctgcc 1620tctgatcctg gctgtggact ggattgtgga ccggaccacc acggtggtga atgtggaagg 1680ggatgccctg ggtgcaggca ttctccacca cctgaatcag aaggcaacaa agaaaggcga 1740gcaggaactt gctgaggtga aagtggaagc catccccaac tgcaagtctg aggaggagac 1800atcgcccctg gtgacacacc agaaccccgc tggccccgtg gccagtgccc cagaactgga 1860atccaaggag tcggttctgt gatggggctg ggctttgggc ttgcctgcca gcagtgatgt 1920cccaccctgt tcacccagcc gccagtcatg gacacagggc actgcccttg ccaactttta 1980ccctcccaag caatgctttg gcccagtcgc tggcctgagg cttacctctc ggcactggca 2040ttgggctccc cagccggaac tggttaccaa ggacaaggac actctgacat tcggcttgat 2100ccatgtccag gtgcaactgt gtgtacacca gggatctgtt tggaaacaac cccttgagct 2160gccaggctca agaaatcatg gactcacagg gtcctgtgtg gttacatctt ggaaaaaatg 2220cagatgtatt tcactctccc cggtcagctc tgcatcaggt gttttctgag caaaccaagg 2280gggtttatag tcatctgtcg cattgcctcg agttgcagta attgaaaaaa tgctcaaatt 2340cttagccatg gctggccttt gctgagctgg gactcaggtg tttaaagagt ttgtgctata 2400gctaggtgtg gatagcttct gatccctggg ttctgggaga ctgcaggtgc cgcacattgt 2460caagttagaa atactccagg tgggtgttag cactgtggtg gtctctggtc cacagcctta 2520ggtaaacaac ttagattctg aggtcaaaga aaaaaggaga gggaatgcag ccttgtgggg 2580gagaagcggg gcagagggtt ctctaatcta atcaggacag gacaggtttc acatacaatt 2640gtcccagttc gcatcccagc cctggggcac ttttctgctt ccttccagag gcctgggcct 2700ctgataacac tttggctttt tctccattca cgctgatttg gcaaaaggcc agagatgggc 2760ctccttccct ggggaggtgt gatgtagtta tcacattcag gacccttgtt gatttatcat 2820ctattatttg aattcaactg gacactctgt aaaatgctgc actgcagcaa aaacaaaacc 2880accaccaccc cagagaaaac catgtactaa ttggagtggg gtacccccat tcacaggttc 2940ccaggtcccc tggctttggc tgatttcaaa atatagagcc ctttcttgcc agtacatcca 3000agtttaaaat tatcagcgaa atggtccatg tttttccaat tacctgctga cacggttcta 3060agctaagtga aggggaagat ctgagagcgt gctgtttgtg gctgttgatg catattcgtg 3120atgtaacagg tcctggggcc tcactttacc ccatttgtaa aatggggcta atgtcacctg 3180cctcttacct acctcagagg gatttggtga agcaaactgt taatcttcga aaacgaccat 3240ttcacttctt ggatatcaag tgctaaccca gtatgttctt cttttttatg taagggacag 3300ctttctccac agagtccttt ctgctggtga ggacagcatt tctgagcagg gctttgttct 3360ctatgtgcat taggactttt atcatgccct tgttctgtgt gtagttactt gacagcatca 3420aatgccgcct cttcctaatg tccttcaagt tttcatgaac tagcaacccc accttccacc 3480atggttctgg gcgcctgatt ttgctgtgac tcccagaccc agccactgtt tctgccaccc 3540tgtaacaggc cattaaagct ccccagtgtt cagcctcctt cactcccttg ttttccctgt 3600tgctatgtgt cacctgggcc ctacagacag gggcacacgc ttatggatgt gtgtaccatt 3660gagatgagaa tgggtagatg gaacggagac catcaagcca cacccccttc ttaaaactgg 3720ggacatgagc ctgagcagaa agggtgaaga agagccatgg gacacagagt tgacccagcc 3780agggggaaag cccagctctc tttaaaccag ctaagccatt ccagtctcct gtgaagccaa 3840aagggaccag gaaccgtgca aaggaaactg gaaacttttc cccgctgggt agagcatgtt 3900gctgatactc ttctgttttc aagggaaaca atcacattgt ttgattccaa atggtaaatg 3960aacactcact attcttcagg cttcagtaaa tctttttttc ttccttcata tatatataca 4020caacacacac acacatatgt atatctatac acacatgtgt gttgtgtata tgcatgtgtg 4080tgtgtgcgtg tgtgtatagt tttagctcca agccaagcaa gtttgtgttt ggatagaggg 4140gaacttaact attaactaca agttgtatgt ctgtggtatc ttgattttcc catttctaaa 4200gatgaatttc acaaagccat aaagcgtgaa attagagctg gacttaagac tcattggccg 4260accatcctgt gtcctggcct ggccctgcag taagaagcgt gtctgggtct ggagaagggt 4320gcttccgaga gtgtgcaggt ggcccttccc cttggaggcg agaagagaga atgtgctgtc 4380tatcttcctg gttttcagtc cacagagtcg gtagaccagg ggttacgtga ctggggaaaa 4440tctcacatct ccttgtctga aaacatttcc cctgctgttc tctttctaac atgttgtggt 4500aaatctgttc agatactgct catctgactg ttttgtacat gtgacaattg ccttaaaacc 4560tagcacagtc ctcagaaatg aataccgtgt ttccactgga aaaaaaaaaa a 4611872686DNAHomo sapiens 87aacctgaagc tctcagagct tccctgtctt catctatcag cccagggaga ggaatcagtg 60gttttccaaa agctgtacct ctttccataa atacaaggat gaagggctga gatgatggca 120gttagaatta tattgagaaa tggtagcggg atctgagaaa gcaaggccat gagttgaaag 180cagagagaag gcggttcgag tggagccctg atgaagttca tgctcatggt tgcccagcca 240ttaacacggg ctcatcacat ctgtttccag attgcttcta gaacttagct accctcgttc 300tataagatgg aatgaaaatg cgtactacat acagatcatg aaaagacgca aagaaaatgc 360atcttcacat tgcagttcag aatcacgccg gcctcattct accgctgctc tctcctggat 420ctcggccacg gatcttttgc tcgcgaaagt tcctccgtct agctgcacac aacgctgctg 480caggaaaccg aggtaaggga tttgccgaga cttagctcca ccacactccc cgaggccccg 540cccctcctct ctggccctcc cctaggccca ggtgtctcgc gttgcacgtg cagttgttgt 600ggttctacgt cacgtggtcc cggaagttca agacagaccc gcctcaaaca tggcggcgcc 660cagcgcgcga ggacgtgatc cgcttctgct ccggcttgga ttgtagcctt gacgaggtct 720gagcgaccat ggaccggccg gggttcgtgg cagcgctggt ggctggtggg gtagcaggtg 780tttctgttga cttgatatta tttcctctgg ataccattaa aaccaggctg cagagtcccc 840aaggatttag taaggctggt ggttttcatg gaatatatgc tggcgttcct tctgctgcta 900ttggatcctt tcctaatgct gctgcatttt ttatcaccta tgaatatgtg aagtggtttt 960tgcatgctga ttcatcttca tatttgacac ctatgaaaca tatgttggct gcctctgctg 1020gagaagtggt tgcctgcctg attcgagttc catctgaagt ggttaagcag agggcacagg 1080tatctgcttc tacaagaaca tttcagattt tctctaacat cttatatgaa gagggtatcc 1140aagggttgta tcgaggctat aaaagcacag ttttaagaga gattcctttt tctttggtcc 1200agtttccctt atgggagtcc ttaaaagccc tctggtcctg gaggcaggat catgtggtgg 1260attcttggca gtcagcagtc tgtggagctt ttgcaggtgg atttgccgct gcagtcacca 1320cccctctaga cgtggcaaag acaagaatta cgctggcaaa ggctggctcc agcactgctg 1380atgggaatgt gctctctgtc ctgcatgggg tctggcggtc acaggggctg gcaggattat 1440ttgcaggtgt cttccctcga atggcagcca tcagtctggg aggtttcatc tttctggggg 1500cttatgaccg aacgcacagc ttgctgttgg aagttggcag aaagagtcct tgaagcagag 1560acaagcctca cctccacttc tgtcaagaga ggggcctgca gtgcaaaccc tcttccgctg 1620agcagctgtc tgaactatag gccccagtgc tgaagaccag ttgtgctaag ataccggcat 1680ggagattgtg ccatccgtgg tataggctgg ctggtatgaa gtcattggcc tgtatgccag 1740agagctaaga gaagaaaacg gggtctgtgg cggtactctg aacaatttcc tcagaacctc 1800ttaataaata agtttggtaa tgctgaggcc aggcctttta gagctttcat ttgatctgta 1860tctgatcttt catttcctgc cacctgatgg tggattcagc agaaggcaag atggttataa 1920ttctaaaaga atagcttgtt tgtttgtttg ggaaaaggag acttggggaa gagttgtgta 1980tgtgggtgtt tctcccccta gttaattcct gttgtgtaag ggtaggcttt gttgaaaaag 2040aaagaaagat tgaactacag gtgcatagca agcactcttt ctgggtaact aggctgctgg 2100ttttaattac cctcagattt cacccataaa aacgcacaat tgtattattt tacagagatg 2160tgtccagcgc cccctgtggt gtgtgagaga aagcagctgc aactcaagtg actaggtggg 2220cccagctggc ttcgtgcagg agggcacggt gggtgagcca ttctcgccat tctcatgtca 2280gactgaaagg agggcctggg ccagctttga aaaggcagga tgaaatggaa aggtcaccac 2340acttagggat tttagacctt gactaacaag ctccaggtgt agaaaaattc aaaacaaaat 2400gtcaggaatc tagcagtgtt gtctgccctg gagcaaacaa acagtatgtg attttgcttc 2460gcctattttt tttttctttt ttgggggaag ataattaaag gcagaatgac tgcgtttgta 2520aaagaaggac caccaactat actgacattt ataaatgaac ctttattaaa gacacttcaa 2580tgccatttgt tagacacttc aatattttac atggttttca atgtacactg taccaaaatt 2640tctataaata aataactttg tacataaaag taaaaaaaaa aaaaaa 2686883909DNAHomo sapiens 88gagcgagagt gtgtcgagtg agtgtgcgtc tgtgtgtccc ggcgagggtg cgcgctcggc 60gccgggagcg cggccagccg agtccggagg catcgggagg tcgagagccg ccgggacccc 120agctctgcgt tcactgcccc gtccggagct ggacttcggg gccggggccg gggccgtgcg 180ccggggacag gcagggccgg gtcgcgggcc gcgcgtcccc caggccggag atctgcgagt 240gaagagggac gagggaaaag aaacaaagcc acagacgcaa cttgagactc ccgcatccca 300aaagaagcac cagatcagca aaaaaagaag atgggccccc cgagcctcgt gctgtgcttg 360ctgtccgcaa ctgtgttctc cctgctgggt ggaagctcgg ccttcctgtc gcaccaccgc 420ctgaaaggca ggtttcagag ggaccgcagg aacatccgcc ccaacatcat cctggtgctg 480acggacgacc aggatgtgga gctgggttcc atgcaggtga tgaacaagac ccggcgcatc 540atggagcagg gcggggcgca cttcatcaac gccttcgtga ccacacccat gtgctgcccc 600tcacgctcct ccatcctcac tggcaagtac gtccacaacc acaacaccta caccaacaat 660gagaactgct cctcgccctc ctggcaggca cagcacgaga gccgcacctt tgccgtgtac 720ctcaatagca ctggctaccg gacagctttc ttcgggaagt atcttaatga atacaacggc 780tcctacgtgc cacccggctg gaaggagtgg gtcggactcc ttaaaaactc ccgcttttat 840aactacacgc tgtgtcggaa cggggtgaaa gagaagcacg gctccgacta ctccaaggat 900tacctcacag acctcatcac caatgacagc gtgagcttct tccgcacgtc caagaagatg 960tacccgcaca ggccagtcct catggtcatc agccatgcag ccccccacgg ccctgaggat 1020tcagccccac aatattcacg cctcttccca aacgcatctc agcacatcac gccgagctac 1080aactacgcgc ccaacccgga caaacactgg atcatgcgct acacggggcc catgaagccc 1140atccacatgg aattcaccaa catgctccag cggaagcgct tgcagaccct catgtcggtg 1200gacgactcca tggagacgat ttacaacatg ctggttgaga cgggcgagct ggacaacacg 1260tacatcgtat acaccgccga ccacggttac cacatcggcc agtttggcct ggtgaaaggg 1320aaatccatgc catatgagtt tgacatcagg gtcccgttct acgtgagggg ccccaacgtg 1380gaagccggct gtctgaatcc ccacatcgtc ctcaacattg acctggcccc caccatcctg 1440gacattgcag gcctggacat acctgcggat atggacggga aatccatcct caagctgctg 1500gacacggagc ggccggtgaa tcggtttcac ttgaaaaaga agatgagggt ctggcgggac 1560tccttcttgg tggagagagg caagctgcta cacaagagag acaatgacaa ggtggacgcc 1620caggaggaga actttctgcc caagtaccag cgtgtgaagg acctgtgtca gcgtgctgag 1680taccagacgg cgtgtgagca gctgggacag aagtggcagt gtgtggagga cgccacgggg 1740aagctgaagc tgcataagtg caagggcccc atgcggctgg gcggcagcag agccctctcc 1800aacctcgtgc ccaagtacta cgggcagggc agcgaggcct gcacctgtga cagcggggac 1860tacaagctca gcctggccgg acgccggaaa aaactcttca agaagaagta caaggccagc 1920tatgtccgca gtcgctccat ccgctcagtg gccatcgagg tggacggcag ggtgtaccac 1980gtaggcctgg gtgatgccgc ccagccccga aacctcacca agcggcactg gccaggggcc 2040cctgaggacc aagatgacaa ggatggtggg gacttcagtg gcactggagg ccttcccgac 2100tactcagccg ccaaccccat taaagtgaca catcggtgct acatcctaga gaacgacaca 2160gtccagtgtg acctggacct gtacaagtcc ctgcaggcct ggaaagacca caagctgcac 2220atcgaccacg agattgaaac cctgcagaac aaaattaaga acctgaggga agtccgaggt 2280cacctgaaga aaaagcggcc agaagaatgt gactgtcaca aaatcagcta ccacacccag 2340cacaaaggcc gcctcaagca cagaggctcc agtctgcatc ctttcaggaa gggcctgcaa 2400gagaaggaca aggtgtggct gttgcgggag cagaagcgca agaagaaact ccgcaagctg 2460ctcaagcgcc tgcagaacaa cgacacgtgc agcatgccag gcctcacgtg cttcacccac 2520gacaaccagc actggcagac ggcgcctttc tggacactgg ggcctttctg tgcctgcacc 2580agcgccaaca ataacacgta ctggtgcatg aggaccatca atgagactca caatttcctc 2640ttctgtgaat ttgcaactgg cttcctagag tactttgatc tcaacacaga cccctaccag 2700ctgatgaatg cagtgaacac actggacagg gatgtcctca accagctaca cgtacagctc 2760atggagctga ggagctgcaa gggttacaag cagtgtaacc cccggactcg aaacatggac 2820ctgggactta aagatggagg aagctatgag caatacaggc agtttcagcg tcgaaagtgg 2880ccagaaatga agagaccttc ttccaaatca ctgggacaac tgtgggaagg ctgggaaggt 2940taagaaacaa cagaggtgga cctccaaaaa catagaggca tcacctgact gcacaggcaa 3000tgaaaaacca tgtgggtgat ttccagcaga cctgtggtat tggccaggag gcctgagaaa 3060gcaagcacgc actctcagtc aacatgacag attctggagg ataaccagca ggagcagaga 3120taacttcagg aagtccattt ttgcccctgc ttttgctttg gattatacct caccagctgc 3180acaaaatgca ttttttcgta tcaaaaagtc accactaacc ctcccccaga agctcacaaa 3240ggaaaacgga gagagcgagc gagagagatt tccttggaaa tttctcccaa gggcgaaagt 3300cattggaatt tttaaatcat aggggaaaag cagtcctgtt ctaaatcctc ttattctttt 3360ggtttgtcac aaagaaggaa ctaagaagca ggacagaggc aacgtggaga ggctgaaaac 3420agtgcagaga cgtttgacaa tgagtcagta gcacaaaaga gatgacattt acctagcact 3480ataaaccctg gttgcctctg aagaaactgc cttcattgta tatatgtgac tatttacatg 3540taatcaacat gggaactttt aggggaacct aataagaaat cccaattttc aggagtggtg 3600gtgtcaataa acgctctgtg gccagtgtaa aagaaaatcc ctcgcagttg tggacatttc 3660tgttcctgtc cagataccat ttctcctagt atttctttgt tatgtcccag aactgatgtt 3720ttttttttaa ggtactgaaa agaaatgaag ttgatgtatg tcccaagttt tgatgaaact 3780gtatttgtaa aaaaaatttt gtagtttaag tattgtcata cagtgttcaa aaccccagcc 3840aatgaccagc agttggtatg aagaaccttt gacattttgt aaaaggccat ttcttgggaa 3900aaaaaaaaa 3909891075DNAHomo sapiens 89gcattcccca cacaacaccc acactcagcc actgcgggcg aggagggcac aaggccaggt 60tcccaagagc tcaggaacat ggagctgatc caggacatct ctcgcccgcc actggagtac 120gtgaaggggg tcccgctcat caagtacttt gcagaggcac tggggcccct gcagagcttc 180caggcccggc ctgatgacct gctcatcagc acctacccca agtccggcac cacctgggtg 240agccagattc tggacatgat ctaccagggc ggtgacctgg aaaagtgtca ccgagctccc 300atcttcatgc gggtgccctt ccttgagttc aaagtcccag ggattccctc agggatggag 360actctgaaaa acacaccagc cccacgactc ctgaagacac acctgcccct ggctctgctc 420ccccagactc tgttggatca gaaggtcaag gtggtctatg ttgcccgcaa cgcaaaggat 480gtggcggttt cctactacca cttctaccac atggccaaag tgtaccctca ccctgggacc 540tgggaaagct tcctggagaa gttcatggct ggagaagtgt cctatgggtc ctggtaccag 600cacgtgcaag agtggtggga gctgagccgc acccaccctg ttctctacct cttctatgaa 660gacatgaagg agaaccccaa aagggagatt caaaagatcc tggagtttgt ggggcgctcc 720ctgccagagg agactgtgga cctcatggtt gagcacacgt cgttcaagga gatgaagaag 780aaccctatga ccaactacac caccgtccgc cgggagttca tggaccacag catctccccc 840ttcatgagga aaggcatggc tggggactgg aagaccacct tcaccgtggc gcagaatgag 900cgcttcgatg cggactatgc ggagaagatg gcaggctgca gcctcagctt ccgctctgag 960ctgtgagagg ggttcctgga gtcactgcag agggagtgtg cgaatcaagc ctgaccaaga 1020ggctccagaa taaagtatga tttgtgttca aaaaaaaaaa aaaaaaaaaa aaaaa 1075902745DNAHomo sapiens 90ctcgcgaggc cggctaggcc cgaatgtcgt tagccgtggg gaaagatggc ggaaaattta 60aaaggctgca gcgtgtgttg caagtcttct tggaatcagc tgcaggacct gtgccgcctg 120gccaagctct cctgccctgc cctcggtatc tctaagagga acctctatga ctttgaagtc 180gagtacctgt gcgattacaa gaagatccgc gaacaggaat attacctggt gaaatggcgt 240ggatatccag actcagagag cacctgggag ccacggcaga atctcaagtg tgtgcgtatc 300ctcaagcagt tccacaagga cttagaaagg gagctgctcc ggcggcacca ccggtcaaag 360accccccggc acctggaccc aagcttggcc aactacctgg tgcagaaggc caagcagagg 420cgggcgctcc gtcgctggga gcaggagctc aatgccaagc gcagccatct gggacgcatc 480actgtagaga atgaggtgga cctggacggc cctccgcggg ccttcgtgta catcaatgag 540taccgtgttg gtgagggcat caccctcaac caggtggctg tgggctgcga gtgccaggac 600tgtctgtggg cacccactgg aggctgctgc ccgggggcgt cactgcacaa gtttgcctac 660aatgaccagg gccaggtgcg gcttcgagcc gggctgccca tctacgagtg caactcccgc 720tgccgctgcg gctatgactg cccaaatcgt gtggtacaga agggtatccg atatgacctc

780tgcatcttcc gcacggatga tgggcgtggc tggggcgtcc gcaccctgga gaagattcgc 840aagaacagct tcgtcatgga gtacgtggga gagatcatta cctcagagga ggcagagcgg 900cggggccaga tctacgaccg tcagggcgcc acctacctct ttgacctgga ctacgtggag 960gacgtgtaca ccgtggatgc cgcctactat ggcaacatct cccactttgt caaccacagt 1020tgtgacccca acctgcaggt gtacaacgtc ttcatagaca accttgacga gcggctgccc 1080cgcatcgctt tctttgccac aagaaccatc cgggcaggcg aggagctcac ctttgattac 1140aacatgcaag tggaccccgt ggacatggag agcacccgca tggactccaa ctttggcctg 1200gctgggctcc ctggctcccc taagaagcgg gtccgtattg aatgcaagtg tgggactgag 1260tcctgccgca aatacctctt ctagccctta gaagtctgag gccagactga ctgagggggc 1320ctgaagctac atgcacctcc cccactgctg ccctcctgtc gagaatgact gccagggcct 1380cgcctgcctc cacctgcccc cacctgctcc tacctgctct acgttcaggg ctgtggccgt 1440ggtgaggacc gactccagga gtcccctttc cctgtcccag ccccatctgt gggttgcact 1500tacaaacccc cacccacctt cagaaatagt ttttcaacat caagactctc tgtcgttggg 1560attcatggcc tattaaggag gtccaagggg tgagtcccaa cccagcccca gaatatattt 1620gtttttgcac ctgcttctgc ctggagattg aggggtctgc tgcaggcctc ctccctgctg 1680ccccaaaggt atggggaagc aaccccagag caggcagaca tcagaggcca gagtgcctag 1740cccgacatga agctggttcc ccaaccacag aaactttgta ctagtgaaag aaagggggtc 1800cctgggctac gggctgaggc tggtttctgc tcgtgcttac agtgctgggt agtgttggcc 1860ctaagagctg tagggtctct tcttcagggc tgcatatctg agaagtggat gcccacatgc 1920cactggaagg gaagtgggtg tccatgggcc actgagcagt gagaggaagg cagtgcagag 1980ctggccagcc ctggaggtag gctgggacca agctctgcct tcacagtgca gtgaaggtac 2040ctagggctct tgggagctct gcggttgcta ggggccctga cctggggtgt catgaccgct 2100gacaccactc agagctggaa ccaagatcta gatagtccgt agatagcact taggacaaga 2160atgtgcattg atggggtggt gatgaggtgc caggcactgg gtagagcacc tggtccacgt 2220ggattgtctc agggaagcct tgaaaaccac ggaggtggat gccaggaaag ggcccatgtg 2280gcagaaggca aagtacaggc caagaattgg gggtggggga gatggcttcc ccactatggg 2340atgacgaggc gagagggaag cccttgctgc ctgccattcc cagaccccag ccctttgtgc 2400tcaccctggt tccactggtc tcaaaagtca cctgcctaca aatgtacaaa aggcgaaggt 2460tctgatggct gccttgctcc ttgctccccc accccctgtg aggacttctc taggaagtcc 2520ttcctgacta cctgtgccca gagtgcccct acatgagact gtatgccctg ctatcagatg 2580ccagatctat gtgtctgtct gtgtgtccat cccgccgacc ccccagacta acctccaggc 2640atggactgaa tctggttctc ctcttgtaca cccctcaacc ctatgcagcc tggagtgggc 2700atcaataaaa tgaactgtcg actgaacaaa aaaaaaaaaa aaaaa 2745914000DNAHomo sapiens 91aaaggcagaa tgagtcctcc caccccctac cctgccaccc ctcccaccca agccacctca 60tttcctcttc ctccccagca ccgacccaca ctgaccaaca caggctgagc agtcaggccc 120acagcatctg accccaggcc cagctcgtcc tggctggcct gggtcggcct ctggagtatg 180gtctggcggg tgcccccttt cttgctcccc atcctcttct tggcttctca tgtgggcgcg 240gcggtggacc tgacgctgct ggccaacctg cggctcacgg acccccagcg cttcttcctg 300acttgcgtgt ctggggaggc cggggcgggg aggggctcgg acgcctgggg cccgcccctg 360ctgctggaga aggacgaccg tatcgtgcgc accccgcccg ggccacccct gcgcctggcg 420cgcaacggtt cgcaccaggt cacgcttcgc ggcttctcca agccctcgga cctcgtgggc 480gtcttctcct gcgtgggcgg tgctggggcg cggcgcacgc gcgtcatcta cgtgcacaac 540agccctggag cccacctgct tccagacaag gtcacacaca ctgtgaacaa aggtgacacc 600gctgtacttt ctgcacgtgt gcacaaggag aagcagacag acgtgatctg gaagagcaac 660ggatcctact tctacaccct ggactggcat gaagcccagg atgggcggtt cctgctgcag 720ctcccaaatg tgcagccacc atcgagcggc atctacagtg ccacttacct ggaagccagc 780cccctgggca gcgccttctt tcggctcatc gtgcggggtt gtggggctgg gcgctggggg 840ccaggctgta ccaaggagtg cccaggttgc ctacatggag gtgtctgcca cgaccatgac 900ggcgaatgtg tatgcccccc tggcttcact ggcacccgct gtgaacaggc ctgcagagag 960ggccgttttg ggcagagctg ccaggagcag tgcccaggca tatcaggctg ccggggcctc 1020accttctgcc tcccagaccc ctatggctgc tcttgtggat ctggctggag aggaagccag 1080tgccaagaag cttgtgcccc tggtcatttt ggggctgatt gccgactcca gtgccagtgt 1140cagaatggtg gcacttgtga ccggttcagt ggttgtgtct gcccctctgg gtggcatgga 1200gtgcactgtg agaagtcaga ccggatcccc cagatcctca acatggcctc agaactggag 1260ttcaacttag agacgatgcc ccggatcaac tgtgcagctg cagggaaccc cttccccgtg 1320cggggcagca tagagctacg caagccagac ggcactgtgc tcctgtccac caaggccatt 1380gtggagccag agaagaccac agctgagttc gaggtgcccc gcttggttct tgcggacagt 1440gggttctggg agtgccgtgt gtccacatct ggcggccaag acagccggcg cttcaaggtc 1500aatgtgaaag tgccccccgt gcccctggct gcacctcggc tcctgaccaa gcagagccgc 1560cagcttgtgg tctccccgct ggtctcgttc tctggggatg gacccatctc cactgtccgc 1620ctgcactacc ggccccagga cagtaccatg gactggtcga ccattgtggt ggaccccagt 1680gagaacgtga cgttaatgaa cctgaggcca aagacaggat acagtgttcg tgtgcagctg 1740agccggccag gggaaggagg agagggggcc tgggggcctc ccaccctcat gaccacagac 1800tgtcctgagc ctttgttgca gccgtggttg gagggctggc atgtggaagg cactgaccgg 1860ctgcgagtga gctggtcctt gcccttggtg cccgggccac tggtgggcga cggtttcctg 1920ctgcgcctgt gggacgggac acgggggcag gagcggcggg agaacgtctc atccccccag 1980gcccgcactg ccctcctgac gggactcacg cctggcaccc actaccagct ggatgtgcag 2040ctctaccact gcaccctcct gggcccggcc tcgccccctg cacacgtgct tctgcccccc 2100agtgggcctc cagccccccg acacctccac gcccaggccc tctcagactc cgagatccag 2160ctgacatgga agcacccgga ggctctgcct gggccaatat ccaagtacgt tgtggaggtg 2220caggtggctg ggggtgcagg agacccactg tggatagacg tggacaggcc tgaggagaca 2280agcaccatca tccgtggcct caacgccagc acgcgctacc tcttccgcat gcgggccagc 2340attcaggggc tcggggactg gagcaacaca gtagaagagt ccaccctggg caacgggctg 2400caggctgagg gcccagtcca agagagccgg gcagctgaag agggcctgga tcagcagctg 2460atcctggcgg tggtgggctc cgtgtctgcc acctgcctca ccatcctggc tgccctttta 2520accctggtgt gcatccgcag aagctgcctg catcggagac gcaccttcac ctaccagtca 2580ggctcgggcg aggagaccat cctgcagttc agctcaggga ccttgacact tacccggcgg 2640ccaaaactgc agcccgagcc cctgagctac ccagtgctag agtgggagga catcaccttt 2700gaggacctca tcggggaggg gaacttcggc caggtcatcc gggccatgat caagaaggac 2760gggctgaaga tgaacgcagc catcaaaatg ctgaaagagt atgcctctga aaatgaccat 2820cgtgactttg cgggagaact ggaagttctg tgcaaattgg ggcatcaccc caacatcatc 2880aacctcctgg gggcctgtaa gaaccgaggt tacttgtata tcgctattga atatgccccc 2940tacgggaacc tgctagattt tctgcggaaa agccgggtcc tagagactga cccagctttt 3000gctcgagagc atgggacagc ctctaccctt agctcccggc agctgctgcg tttcgccagt 3060gatgcggcca atggcatgca gtacctgagt gagaagcagt tcatccacag ggacctggct 3120gcccggaatg tgctggtcgg agagaaccta gcctccaaga ttgcagactt cggcctttct 3180cggggagagg aggtttatgt gaagaagacg atggggcgtc tccctgtgcg ctggatggcc 3240attgagtccc tgaactacag tgtctatacc accaagagtg atgtctggtc ctttggagtc 3300cttctttggg agatagtgag ccttggaggt acaccctact gtggcatgac ctgtgccgag 3360ctctatgaaa agctgcccca gggctaccgc atggagcagc ctcgaaactg tgacgatgaa 3420gtgtacgagc tgatgcgtca gtgctggcgg gaccgtccct atgagcgacc cccctttgcc 3480cagattgcgc tacagctagg ccgcatgctg gaagccagga aggcctatgt gaacatgtcg 3540ctgtttgaga acttcactta cgcgggcatt gatgccacag ctgaggaggc ctgagctgcc 3600atccagccag aacgtggctc tgctggccgg agcaaactct gctgtctaac ctgtgaccag 3660tctgaccctt acagcctctg acttaagctg cctcaaggaa tttttttaac ttaagggaga 3720aaaaaaggga tctggggatg gggtgggctt aggggaactg ggttcccatg ctttgtaggt 3780gtctcatagc tatcctgggc atccttcttt ctagttcagc tgccccacag gtgtgtttcc 3840catcccactg ctcccccaac acaaaccccc actccagctc cttcgcttaa gccagcactc 3900acaccactaa catgccctgt tcagctactc ccactcccgg cctgtcattc agaaaaaaat 3960aaatgttcta ataagctcca ttaaaaaaaa aaaaaaaaaa 4000923658DNAHomo sapiens 92aaggaggagt gcactggccg ggatcggtgc agcgctcaca ctcactcaca gtcactctct 60ctgagcgcgt ctcgctcgct ctcatacacg cccggagccc aggagcgctc aggatcccga 120gcgccgcgaa aaagttcccc cggcttttgc tggagactca tcgttttggg aagtgcattt 180gcttcgtggc tccgccgagc ctgctgaatc ctgtcctcgc ggcacgggac cccgggatcg 240ctgaccgctg ccgccgccgc ctctgcctcc cggactatcg gcagcctcgg caacaatagt 300ggcggccgcc cccagcgagg ctccgggagc ccttgcctgc gggggtccgg ggactcgagc 360cggcctccgc ctcccggacg cacagccagc gtggtccccg cgtgcaacgc gagcgccggg 420gagtggctcc tgctttgccc ctcgtggggg ccgagccaag accagtctgc aaactccatc 480ccgccggctg gaagaagtcg cggagccggc accaaacccg cagcgtcttc ccgcgcggat 540cccgggactt aaaaagccgg ggccaccccg gcccaggacg ggatgcgggt cggtccggtg 600cgctctgcca tgagcggcgc ctcgcagccc cgcggcccgg ccctgctctt cccagccacc 660cgaggcgtcc cggccaaacg cctgctggac gccgacgacg cggcggctgt ggcggccaag 720tgcccgcgcc tctccgagtg ctccagcccc ccggactacc tcagcccccc cggctcgccc 780tgcagcccgc agcccccgcc tgccgctccg ggggccggcg gaggctccgg gagcgcgccg 840gggcccagcc gcatcgccga ctacctgctg ctgcccctag ccgagcgcga gcatgtgtcc 900cgggcgctgt gcatccacac tggacgcgag ctgcgctgca aggtgtttcc cattaaacac 960taccaggaca aaatcaggcc ttacatccag ctgccatcgc acagcaacat tactggcatt 1020gtggaagtga tccttgggga aaccaaggcc tatgtcttct ttgagaagga ctttggggac 1080atgcactcct atgtgcgaag ccggaagagg ctgcgggaag aggaagccgc ccggctcttc 1140aagcagattg tctccgccgt cgcccactgc caccagtcag ccatcgtgct gggggacctg 1200aagcttagga agttcgtctt ctccacggag gagagaaccc agcttagact agaaagtcta 1260gaagacacac acataatgaa gggggaagat gatgctttgt cagacaaaca tggctgccca 1320gcctacgtga gccctgagat cctcaacacc actgggacct actccggaaa ggctgcggac 1380gtttggagcc tgggggtgat gctctacacc cttctggttg gacgataccc cttccatgac 1440tcagacccca gtgccctttt ctccaaaatt cggcgtggac agttctgcat tcctgagcac 1500atttccccca aagccaggtg cctcattcgc agcctcttga gacgggagcc ctccgagaga 1560ctcactgccc ccgagatcct actgcacccc tggtttgagt ccgtcttgga acccgggtac 1620atcgactcag aaataggaac ttcagaccag attgttccag agtaccagga ggacagtgac 1680attagttcct tcttctgcta atccccaaaa cctcagaaac ctcataattc ttaacacctg 1740gcatttccat ttctaaagat ggacaggccc tttggcgtgg taccaaccag ataatgactg 1800catcaggatg aaagctgctg aactcggcat ggcgcctcct cttctctgtt gggatgagtg 1860actttattga tttgagcagc atatgctgtg attggctgcc ctgcaaattt gtttccctta 1920aggaaccctc accaactatc tctgctggat ttgggagttc cgcatctttt gtggagggca 1980gagtatggac atcttacacc cggtggtcaa gtgtgtaata aacttgagca ttcgaatggg 2040agaaaaagca aatcgcacaa tgacatattt tgagtaataa ccgtattttt cacagggtga 2100caaattgggc caataaatct gccatctttg aactcatctt tggtggctag actgctacgg 2160cagcttctct gatgggaaag ttcctttttt ggcttaacac tcaccctttc ttcacactca 2220catttaccaa tgactctgct ccgtttttgg agcagactgt tttaagttgc tcaggagcct 2280gatggaacca tgaaccgaga ctcttctctg tttcctgcca agacctcatc tgcactaatg 2340ccttctccct gaccttgaca cttccccctt tagctataaa agcacttacc agccgaacgt 2400ggaacagtat cacaaaagat tccatctccc aacgatttca gaactctgag ctcagagaga 2460ctccagattt taaaaaataa tttgagtgct tggaaactat tagcttttta agttccttcc 2520aaatatgtta gtacctaccc tttacttttt ccccaagacc atctcagggt ggagcattct 2580gtctaagaga agaaagataa ggaggctccc acccacctct cccaagagca gacattaaac 2640atctttgtgc tttgaagaga gtgaattttg gatagtcttg tgattctcag actaacttcc 2700agaattatac tttaacccct cccagatatg gtccgccttt ggcattgtgt gtacatctgc 2760agttttgcat ggtgggttgt taatatttca aatgtgtggt ttatgaatac gtctgtataa 2820tcggcttctg gagtgaaaca gcaaacccca aatcttcaaa gttggaagga actttaaaaa 2880tcatccggtc caatctcttt cctctttctg ccacctccca aggcagaaat cccctcttca 2940gcttcttttg taggtgggaa tccagcctct gttagatatg tccagagatg gaaactcact 3000cccctacaaa agatggagct taatggagaa attgcaactt tcattaaaaa acaaattcag 3060atgaaatatc agtaactgtc ttggacagtg ctgaaatcag gtggttaaac gggtaaacaa 3120aatatactgt attttgagaa atggcacaaa aacaggcagt catctttaag ggctatgcct 3180aggcaaacta ctaacatgca ttgtgagaat gccgtgtata cctcacgtac tgtgtacttt 3240gtacatatat tttacctttt atacctatgt tcgattttgt tttgttttgt tttgttctgg 3300ctttgaggct tgttttgttg tctgtgtctg tctgaataac ctgcgtgtct aaaaccacgt 3360gaaatgtgaa tgattattgg caatattacc ttgacagaat catgggactt tgagaagagg 3420gaggacagag gcctctgtcg cactaacgct ctcgtggttg ctcgactgtt gtatctgtga 3480tacattatcc gactaaggac tctgggctgg cagggccttc tgccgggaaa gctagaaaca 3540ctaggttctt cctgtacata cgtgtatata tgtgaacagt gagatggccg tttctgactt 3600gtagagaaat tttaataaac ctggtttcgt aaaaaaaaaa aaaaaaaaaa aaaaaaaa 3658932408DNAHomo sapiens 93cgggtcagga ggtggtgcgc ctcgcgcggc agattcgaag ctagggcggg gcccgcgggc 60tgaggcagcg gctgtggcgg cgacgctggg cgtgaggtgg cggcggccgc gccctggttg 120ggtccccact gctctcgggg gcgccatgga cgaggccgtg ggcgacctga agcaggcgct 180tccctgtgtg gccgagtcgc caacggtcca cgtggaggtg catcagcgcg gcagcagcac 240tgcaaagaaa gaagacataa acctgagtgt tagaaagcta ctcaacagac ataatattgt 300gtttggtgat tacacatgga ctgagtttga tgaacctttt ttgaccagaa atgtgcagtc 360tgtgtctatt attgacacag aattaaaggt taaagactca cagcccatcg atttgagtgc 420atgcactgtt gcacttcaca ttttccagct gaatgaagat ggccccagca gtgaaaatct 480ggaggaagag acagaaaaca taattgcagc aaatcactgg gttctacctg cagctgaatt 540ccatgggctt tgggacagct tggtatacga tgtggaagtc aaatcccatc tcctcgatta 600tgtgatgaca actttactgt tttcagacaa gaacgtcaac agcaacctca tcacctggaa 660ccgggtggtg ctgctccacg gtcctcctgg cactggaaaa acatccctgt gtaaagcgtt 720agcccagaaa ttgacaatta gactttcaag caggtaccga tatggccaat taattgaaat 780aaacagccac agcctctttt ctaagtggtt ttcggaaagt ggcaagctgg taaccaagat 840gtttcagaag attcaggatt tgattgatga taaagacgcc ctggtgttcg tgctgattga 900tgaggtggag agtctcacag ccgcccgaaa tgcctgcagg gcgggcaccg agccatcaga 960tgccatccgc gtggtcaatg ctgtcttgac ccaaattgat cagattaaaa ggcattccaa 1020tgttgtgatt ctgaccactt ctaacatcac cgagaagatc gacgtggcct tcgtggacag 1080ggctgacatc aagcagtaca ttgggccacc ctctgcagca gccatcttca aaatctacct 1140ctcttgtttg gaagaactga tgaagtgtca gatcatatac cctcgccagc agctgctgac 1200cctccgagag ctagagatga ttggcttcat tgaaaacaac gtgtcaaaat tgagccttct 1260tttgaatgac atttcaagga agagcgaggg cctcagcggc cgggtcctga gaaaactccc 1320ctttctggct catgcgctgt atgtccaggc ccccaccgtc accatagagg ggttcctcca 1380ggccctgtct ctggcagtgg acaagcagtt tgaagagaga aagaagcttg cagcttacat 1440ctgatcctgg gcttccccat ctggtgcttt tcccatggag aacacacaac cagtaagtga 1500ggttgcccca cacagccgtc tcccagggaa tcccttctgc aaaccaaacg ttacttagac 1560tgcaagctag aaagccacca aggccaggct ttgttaaaag aagtgtattc tatttatgtt 1620gttttaaaat gcatactgag agacaaacat cttgtcattt tcactgtttg taaaagataa 1680ttcagattgt ttgtctcctt gtgaagaacc atcgaaacct gtttgttccc agcccacccc 1740cagtggatgg gatgcataat gccagcaagt tttgtttaac agcaaaaaag gaagattaat 1800gcaggtgtta tagaagccag aagagaaact gtgtcaccct aaagaagcat ataatcatag 1860cattaaaaat gcacacatta ctccaggtgg aaggtggcaa ttgctttctg atatcagctc 1920gtttgattta gtgcaaaaat gttttcaaga ctatttaatg gatgtaaaaa agcctatttc 1980tacattatac caactgagaa aaaaatggtc ggtaaagtgt tctttcataa taaataatca 2040gacatggtcc catttgcagg aaaagtgcag actctgagtg ttccagggaa acacatgctg 2100gacatccctt gtaacccggt atgggcgccc ctgcattgct gggatgtttc tgcccacggt 2160tttgtttgtg caataacgtt atcacatttc taatgaggat tcacattaat ataatataaa 2220ataaataggt cagttactgg tctctttctc cgaatgttat gttttgcttt tatctcacag 2280taaaataaat ataattaatg gtttgcatgt gaaattcact tttgaaagaa catgttacct 2340taccttttgt tttagaagtt ttcaagtatt aaaatatttt ttagaatttt aaaaaaaaaa 2400aaaaaaaa 24089412608DNAHomo sapiens 94cgcgccgggg cctggtgctc ggtcggcggg tgctgccgct ttaagcgggg gcgggactgc 60gcgcggccga gcggttgcga cgagggctcg gctgggggtc gccggggtcg cgggccgggc 120ctgcaggagc cgggccgccg aggtcggggc tggttgaact catggacctg atacttttct 180cttgagaagc aaaccagccc aaaagaaaaa tggcgtttgt tgcaacacag ggggccacgg 240tggttgacca gaccactttg atgaaaaagt accttcagtt tgtggcagct ctcacagatg 300tgaatacacc tgatgaaaca aagttgaaaa tgatgcaaga agttagtgaa aattttgaga 360atgtcacgtc atctcctcag tattctacat tcctagaaca tatcatccct cgattcctta 420catttctcca agatggagaa gttcagtttc ttcaggagaa accagcacag caactgcgga 480agctcgtact tgaaataatt catagaatac caaccaacga acatcttcgt cctcacacaa 540aaaatgtttt gtctgtgatg tttcgctttt tagagacgga aaatgaagaa aatgttctta 600tttgtctaag aataattatt gagctacaca aacagttcag gccaccgatc acacaagaaa 660ttcatcattt tctggatttt gtgaaacaga tttacaagga gcttccaaaa gtagtgaacc 720gctactttga gaaccctcaa gtgatccccg agaacacagt gcctccccca gaaatggttg 780gtatgataac aacgattgct gtgaaagtca acccggagcg tgaggacagt gagactcgaa 840cacattccat cattccgagg ggatcacttt ctctgaaagt gttggcagaa ttgcccatta 900ttgttgtttt aatgtatcag ctctacaaac tgaacatcca caatgttgtt gctgagtttg 960tgcccttgat catgaacacc attgccattc aggtgtctgc acaagcgagg caacataagc 1020tttacaacaa ggagttgtat gctgacttca ttgctgctca gattaaaaca ttgtcatttt 1080tagcttacat tatcaggatt taccaggagt tggtgactaa gtattctcag cagatggtga 1140aaggaatgct ccagttactt tcaaattgtc cagcagagac tgcacacctc agaaaggagc 1200ttctgattgc tgccaaacac atcctcacca cagagctgag aaaccagttc attccttgca 1260tggacaagct gtttgatgaa tccatactaa ttggctcagg atatactgcc agagagactc 1320taaggcccct cgcctacagc acgctggccg acctcgtgca ccatgtccgc cagcacctgc 1380ccctcagcga cctctccctc gccgtccagc tcttcgccaa gaacatcgac gatgagtccc 1440tgcccagcag catccagacc atgtcctgca agctcctgct gaacctggtg gactgcatcc 1500gttccaagag cgagcaggag agtggcaatg ggagagacgt cctgatgcgg atgctggagg 1560ttttcgttct caaattccac acaattgctc ggtaccagct ctctgccatt tttaagaagt 1620gtaagcctca gtcagaactt ggagccgtgg aagcagctct gcctggggtg cccactgccc 1680ctgcagctcc tggccctgct ccctccccag cccctgtccc tgccccacct ccacccccgc 1740ccccaccccc acctgccacc cctgtgaccc cggcccccgt gcctcccttc gagaagcaag 1800gagaaaagga caaggaagac aagcagacat tccaagtcac agactgtcga agtttggtca 1860aaaccttggt gtgtggtgtc aagacaatca cgtggggcat aacatcatgc aaagcacctg 1920gtgaagctca gttcattccc aacaagcagt tacaacccaa agagacacag atttacatca 1980aacttgtgaa atatgcaatg caagctttag atatttatca ggtccagata gcaggaaatg 2040gacagacata catccgtgtg gccaactgcc agactgtgag aatgaaagag gagaaggagg 2100tattggagca tttcgctggt gtgttcacaa tgatgaaccc cttaacgttc aaagaaatct 2160tccaaactac ggtcccttat atggtggaga gaatctcaaa aaattatgct cttcagattg 2220ttgccaattc cttcttggca aatcctacta cctctgctct gtttgctacg attctggtgg 2280aatatctcct tgatcgcctg ccagaaatgg gctccaacgt ggagctctcc aacctgtacc 2340tcaagctgtt caagctggtc tttggctctg tctccctctt tgcagctgaa aatgaacaaa 2400tgctgaagcc tcacttgcac aagattgtga acagctctat ggagctcgcg cagactgcca 2460aggaacccta caactacttc ttgctgctac gggcgctgtt tcgctctatt ggtggaggta 2520gccacgatct cttgtatcag gagttcttgc ctctccttcc aaacctcctg caagggctga 2580acatgcttca gagtggcctg cacaagcagc acatgaagga cctctttgtg gagctgtgtc 2640tcaccgtccc tgtgcggctg agctcgcttt tgccgtacct gcccatgctt atggatccct 2700tggtgtctgc actcaatggg tctcagacat tggtcagcca aggcctcagg acgctggagc 2760tgtgtgtgga caacctgcag cccgacttcc tctacgacca catccagccg gtgcgcgcag 2820agctcatgca ggctctgtgg cgcaccttac gcaaccctgc

tgacagcatc tcccacgtgg 2880cctaccgtgt gctcggtaag tttggcggca gtaacaggaa gatgctgaag gagtcgcaga 2940agctgcacta cgttgtgacc gaggttcagg gccccagcat cactgtggag ttttccgact 3000gcaaagcttc tctccagctc cccatggaga aggccattga aactgctctg gactgcctga 3060aaagcgccaa cactgagccc tactaccgga ggcaggcgtg ggaagtgatc aaatgcttcc 3120tggtggccat gatgagcctg gaggacaaca agcacgcact ctaccagctc ctggcacacc 3180ccaactttac agaaaagacc atccccaatg ttatcatctc acatcgctac aaagcccagg 3240acactccagc ccggaagact tttgagcagg ccctgacagg cgccttcatg tctgctgtca 3300ttaaggacct gcggcccagc gccctgccct ttgtcgccag cttgatccgc cactatacga 3360tggtggcagt cgcccagcag tgtggccctt tcttgctgcc ttgctaccag gtgggcagcc 3420agcccagcac agccatgttt cacagtgaag aaaatggctc gaaaggaatg gatcctttgg 3480ttctcattga tgcaattgct atttgtatgg catatgaaga aaaggagctt tgcaaaatcg 3540gggaggtggc cctagctgtg atatttgatg ttgcaagtat catcctgggc tccaaggaga 3600gggcctgcca gctgcccctg ttttcttaca tcgtggagcg cctgtgtgca tgttgttatg 3660aacaggcgtg gtatgcaaag ctggggggtg tggtgtctat taagtttctc atggagcggc 3720tgcctctcac ttgggttctc cagaaccagc agacattcct gaaagcactt ctctttgtca 3780tgatggactt aactggagag gtttccaatg gggcagtcgc tatggcaaag accacgctgg 3840agcagcttct gatgcggtgc gcaacgcctt taaaagacga ggagagagcc gaagagatcg 3900tggccgccca ggaaaagtct ttccaccatg tgacacacga cttggttcga gaagtcacct 3960ctccaaactc cactgtgagg aagcaggcca tgcattcgct gcaggtgttg gcccaggtca 4020ctgggaagag tgtcacggtg atcatggaac cccacaaaga ggtcctgcag gatatggtcc 4080cccctaagaa gcacctgctc cgacaccagc ctgccaacgc acagattggc ctgatggagg 4140ggaacacgtt ctgtaccacg ttgcagccca ggctcttcac aatggacctt aacgtggtgg 4200agcataaggt gttctacaca gagctgttga atttgtgtga ggctgaagat tcagctttaa 4260caaagctgcc ctgttataaa agccttccgt cactcgtacc tttacgaatt gcggcattaa 4320atgcacttgc tgcctgcaat taccttcctc agtccaggga gaaaatcatc gctgcactct 4380tcaaagccct gaattccacc aatagtgagc tccaagaggc cggagaagcc tgtatgagaa 4440agtttttaga aggtgctacc atagaagtcg atcaaatcca cacacatatg cgacctttgc 4500tgatgatgct gggagattac cggagcttga cgctgaatgt tgtgaatcgc ctgacttcgg 4560tcacgaggct cttcccaaat tccttcaatg ataaattttg tgatcagatg atgcaacatc 4620tgcgcaagtg gatggaagtg gtggtgatca cccacaaagg gggccagagg agcgacggaa 4680acgaaatgaa gatttgctca gcaattataa acctttttca tctgatcccg gctgctcctc 4740agacactggt gaagcctttg ctagaggttg tcatgaaaac ggagcgggcg atgctgatcg 4800aggcggggag tccattccga gagcccctga tcaagttcct gactcgacat ccctcgcaga 4860cagtggagct gttcatgatg gaagccacac tgaacgatcc ccagtggagc agaatgttta 4920tgagtttttt aaaacacaaa gacgccagac ctctgcggga tgtgctggct gccaacccca 4980acaggttcat caccctgctg ctgccggggg gtgcccagac ggctgtgcgc cccggttcgc 5040ccagcaccag caccatgcgc ctggacctcc agttccaggc catcaagatc ataagcatta 5100tagtgaaaaa cgatgactcc tggctggcca gccagcactc tctggtgagc cagttgcgac 5160gtgtgtgggt gagtgagaac ttccaagaga ggcaccgcaa ggagaacatg gcagccacca 5220actggaagga gcccaagctg ctggcctact gcctgctgaa ctactgcaaa aggaattacg 5280gagatataga attgctgttc cagctgctcc gagcctttac tggtcgtttt ctctgcaaca 5340tgacattctt aaaagagtat atggaggaag agattcccaa aaattacagc atcgctcaga 5400aacgtgccct gttctttcgc tttgtagact tcaacgaccc caacttcgga gatgaattaa 5460aagctaaagt tctgcagcat atcttgaatc ctgctttctt gtacagcttt gagaaggggg 5520aaggagagca gctcttggga cctcccaatc cagaaggaga taacccagaa agcatcacca 5580gtgtgtttat taccaaggtc ctggaccccg agaagcaggc ggacatgctg gactcgctgc 5640ggatctacct gctgcagtac gccacgctgc tggtggagca cgccccccac cacatccatg 5700acaacaacaa gaaccgcaac agcaagctgc gccgcctcat gaccttcgcc tggccctgcc 5760tgctctccaa ggcctgcgtg gacccagcct gcaagtacag cggacacttg ctcctggcgc 5820acattatcgc caaattcgcc atacacaaga agatcgtcct gcaggttttt catagtctcc 5880tcaaggctca cgcaatggaa gctcgagcga tcgtcagaca ggcgatggcc attctgaccc 5940cggcggtgcc ggccaggatg gaggacgggc accagatgct gacccactgg acccggaaga 6000tcattgtgga ggaggggcac accgtcccgc agctggtcca cattctgcac ctgatagtgc 6060aacacttcaa ggtgtactac ccggtacggc accacttggt gcagcacatg gtgagcgcca 6120tgcagaggct gggcttcacg cccagtgtca ccatcgagca gaggcggctg gccgtggacc 6180tgtctgaagt cgtcatcaag tgggagctgc agaggatcaa ggaccagcag ccggattcag 6240atatggaccc aaattccagt ggagaaggag tcaattctgt ctcatcctcc attaagagag 6300gcctgtccgt ggattctgcc caggaagtga aacgctttag gacggccacc ggagccatca 6360gtgcagtctt tgggaggagc cagtcgctac ctggagcaga ctctctcctc gccaagccca 6420ttgacaagca gcacacagac actgtggtga acttccttat ccgcgtggcc tgtcaggtta 6480atgacaacac caacacagcg gggtcccctg gggaggtgct ctctcgccgg tgtgtgaacc 6540ttctgaagac tgcgttgcgg ccagacatgt ggcccaagtc cgaactcaag ctgcagtggt 6600tcgacaagct gctgatgact gtggagcagc caaaccaagt gaactatggg aatatctgca 6660cgggcctaga agtgctgagc ttcctgctaa ctgtcctcca gtccccagcc atcctcagta 6720gcttcaaacc tctgcagcgt ggaattgccg cctgcatgac atgtggaaac accaaggtgt 6780tgcgagccgt ccacagcctt ctctcgcgcc tgatgagcat tttcccaaca gagccgagta 6840cttccagtgt ggcctccaaa tatgaagagc tggagtgcct ctacgcagcc gtcggaaagg 6900tcatctatga agggctcacc aactacgaga aggccaccaa tgccaatccc tcccagctct 6960tcgggaccct tatgatcctc aagtctgcct gcagcaacaa ccccagctac atagacaggc 7020tgatctccgt ctttatgcgc tccctgcaga agatggtccg ggagcattta aaccctcagg 7080cagcgtcagg aagcaccgaa gccacctcag gtacaagcga gctggtgatg ctgagtctgg 7140agctggtgaa gacgcgcctg gcagtgatga gcatggagat gcggaagaac ttcatccagg 7200ccatcctgac atccctcatc gaaaaatcac cagatgccaa aatcctccgg gctgtggtca 7260aaatcgtgga agaatgggtc aagaataact ccccaatggc agccaatcag acacctacac 7320tccgggagaa gtccattttg cttgtgaaga tgatgactta catagaaaaa cgctttccgg 7380aagaccttga attaaatgcc cagtttttag atcttgttaa ctatgtctac agggatgaga 7440ccctctctgg cagcgagctg acggcgaaac ttgagcctgc ctttctctct gggctgcgct 7500gtgcccagcc actcatcagg gcaaagtttt tcgaggtttt tgacaactcc atgaaacgtc 7560gtgtctacga gcgcttgctc tatgtgacct gttcgcagaa ctgggaagcc atggggaacc 7620acttctggat caagcagtgc attgagctgc ttctggccgt gtgtgagaag agcaccccca 7680ttggcaccag ctgccaagga gccatgctcc cgtccatcac caacgtcatc aacctggccg 7740atagccacga ccgtgccgcc ttcgccatgg tcacacatgt caagcaggag ccccgggagc 7800gggagaacag cgagtccaaa gaggaggatg tagagataga catcgaacta gctcctgggg 7860atcagaccag cacgcccaaa accaaagaac tttcagaaaa ggacattgga aaccagctgc 7920acatgctaac caacaggcac gacaagtttc tggacactct ccgagaggtg aagactggag 7980cgctgctcag cgctttcgtt cagctgtgcc acatttccac gacgctggca gagaagacgt 8040gggtccagct tttccccaga ttgtggaaga tcctctctga cagacagcag catgcactcg 8100cgggtgagat aagtccattt ctgtgcagcg gcagtcacca ggtgcagcgg gactgccagc 8160ccagcgcgct gaactgcttt gtggaagcca tgtcccagtg cgtgccgcca atccccatcc 8220gaccctgcgt cctgaagtac ctggggaaga cacacaacct ctggttccgg tccacgctga 8280tgttggagca ccaggctttt gaaaagggtc tgagtcttca gattaagccg aagcaaacaa 8340cggagtttta tgagcaggag agcatcaccc cgccgcagca ggagatactg gattcccttg 8400cggagcttta ctccctgtta caagaggaag atatgtgggc tggtctgtgg cagaagcggt 8460gcaagtactc ggagacagcg actgcgattg cttacgagca gcacgggttc tttgagcagg 8520cacaagaatc ctatgaaaag gcaatggata aagccaaaaa agaacatgag aggagtaacg 8580cctcccctgc tattttccct gaataccagc tctgggaaga ccactggatt cgatgctcca 8640aggaattgaa ccagtgggaa gccctgacgg agtacggtca gtccaaaggc cacatcaacc 8700cctacctcgt cctggagtgc gcctggcggg tgtccaactg gactgccatg aaggaggcgc 8760tggtgcaggt ggaagtgagc tgtccgaagg agatggcctg gaaggtgaac atgtaccgcg 8820gatacctggc catctgccac cccgaggagc agcagctcag cttcatcgag cgcctggtgg 8880agatggccag cagcctggcc atccgcgagt ggcggcggct gccccacgta gtgtcccacg 8940tgcacacgcc tctcctacag gcagcccagc aaatcatcga actccaggaa gctgcacaaa 9000tcaacgcagg cttacagcca accaacctgg gaaggaacaa cagcctgcac gacatgaaga 9060cggtggtgaa gacctggagg aaccgactgc ccatcgtgtc tgacgacttg tcccactgga 9120gcagcatctt catgtggagg cagcatcatt accaggcgat tgtaactgcc tatgagaata 9180gctctcagca tgatcccagt tcaaataacg ctatgcttgg ggttcatgca tcagcttcag 9240cgatcatcca gtatggaaaa atcgcccgga aacaaggact ggtcaatgta gctctggata 9300tattaagtcg gattcatact attccaactg ttcctatcgt ggattgcttc cagaagattc 9360gacagcaagt taaatgctac ctccagctgg caggcgtcat gggcaaaaac gagtgcatgc 9420agggccttga agttattgaa tctacaaatt taaaatactt cacaaaagag atgacagccg 9480aattttatgc actgaaggga atgttcttgg ctcagatcaa caagtccgag gaggcaaaca 9540aagccttctc tgcagctgtg cagatgcacg atgtgctggt gaaagcctgg gccatgtggg 9600gcgactacct ggagaacatc tttgtgaagg agcggcagct gcacctgggc gtgtctgcca 9660tcacctgcta cctgcacgcc tgccggcatc agaacgagag caaatcgagg aaatacttag 9720ccaaggtgct gtggcttttg agttttgatg atgacaaaaa cactttggca gatgccgtcg 9780acaagtactg cattggtgtg ccacccatcc agtggctggc ctggatccca cagctgctca 9840cctgcctggt tggctcggag ggaaagctgc tcttgaacct cattagccag gttggacgcg 9900tgtatcccca agcggtctac tttcccatcc ggaccctgta cctgaccctg aaaatagaac 9960agcgggaacg ctacaagagc gatccagggc ccataagagc aacagcaccc atgtggcgct 10020gcagccgaat catgcacatg cagcgagagc tccaccccac ccttctgtct tccctggaag 10080gcatcgtcga tcagatggtc tggttcagag aaaattggca tgaagaggtt ctcaggcagc 10140tccaacaggg cctggcgaaa tgttactccg tggcgtttga gaaaagtgga gcggtgtccg 10200atgctaaaat caccccccac actctcaatt ttgtgaagaa gttggtgagc acgtttgggg 10260tgggcctgga gaatgtgtcc aacgtctcga ccatgttctc cagcgcagcc tctgagtctc 10320tggcccggcg ggcgcaggcc actgcacaag accctgtctt tcagaagctg aaaggccagt 10380tcacgacgga ttttgacttc agcgttccag gatccatgaa gcttcataat cttatttcta 10440agttgaaaaa gtggatcaaa atcttggagg ccaagaccaa gcaactcccc aaattcttcc 10500tcatagagga aaagtgccgg ttcttgagca atttctcggc acagacagct gaagtggaaa 10560ttcctgggga gtttctgatg ccaaagccaa cgcattatta catcaagatt gcacggttca 10620tgccccgggt agagattgtg cagaagcaca acaccgcagc ccggcggctg tacatccggg 10680gacacaatgg caagatctac ccatacctcg tcatgaacga cgcctgcctc acagagtcac 10740ggcgagagga gcgtgtgttg cagctgctgc gtctgctgaa cccctgtttg gagaagagaa 10800aggagaccac caagaggcac ttgtttttca cagtgccccg ggttgtggca gtttccccac 10860agatgcgcct cgtggaggac aacccctctt cactttccct tgtggagatc tacaagcagc 10920gctgcgccaa gaagggcatc gagcatgaca accccatctc ccgttactat gaccggctgg 10980ctacggtgca ggcgcgggga acccaagcca gccaccaggt cctccgcgac atcctcaagg 11040aggttcagag taacatggtg ccgcgcagca tgctcaagga gtgggcgctg cacaccttcc 11100ccaatgccac ggactactgg acgttccgga agatgttcac catccagctg gctctgatag 11160gcttcgcgga attcgtcctg catttaaata gactcaaccc cgagatgtta cagatcgctc 11220aggacactgg caaactgaat gttgcctact ttcgatttga cataaacgac gcgactggag 11280acctggatgc caaccgtcct gtcccatttc gactcacgcc caacatttct gagtttctga 11340ccaccatcgg ggtctccggc ccgttgacag cgtccatgat tgcggtcgcc cggtgcttcg 11400cccagccaaa ctttaaggtg gatggcattc tgaaaacggt tctccgggac gagatcattg 11460cttggcacaa aaaaacacaa gaggacacgt cctctcctct ctcggccgcc gggcagccag 11520agaacatgga cagccagcaa ctggtgtccc tggttcagaa agccgtcacc gccatcatga 11580cccgcctgca caacctcgcc cagttcgaag gcggggaaag caaggtgaac accctggtgg 11640ccgcggcaaa cagcctggac aatctgtgcc gcatggaccc cgcctggcac ccctggctgt 11700gactgtggcc gccacggcca cccggaatgt gaagggcgct ccgggctctg agcccgcagc 11760ttttacgact tctccctgcc tcgttcctta tattcacaga agccccatag tttcactggg 11820ttgcggttat tttcctggta gtttgcgtgt aagaaaggga gaatatagtt ttagaggaag 11880ctgaactatg acgatgctgg gcgaagcggt tggaaatggc agagctgaaa cttattccaa 11940gctttcaaaa taatctttta agaagccagg attctccggt ctggaatttc tgagtgagtc 12000ctttttttat ggtgtcctcc ctctgtgaat gtacaggcgg aactgtacga acagctccct 12060tccatccatt tttaactctt tcggaaataa cacctcacag cagcttcgtg cttttgtaca 12120gacctttgta acaagtgtac agaaaactca ttttgtttga gaaacaggag ttgatgaacc 12180catcatgctg gtttttctct gagcacaaag ttttaggctg tacacagcca gccttgggaa 12240tctcgttgag cgttcggcgt ggatccacgg ggccaggcca ccctgcggga gcgccacacg 12300catccacttc ggattcagtg ggtgaagaca gaactctgag agtctgcagg cggctcctgt 12360gctttttatt tctggctctt cggatgtctt ctagacattt actatcactg cacctgaaga 12420aaaaatcact tttaccttcc taatttaaaa agacaaaaca gaaatgtacg ttccttcgct 12480agctttagtc tttctgttcc catttttata aatctgagca ttgataatgt tctatctaaa 12540tttgtacagt gtgatttttt tttttagaat aaatatttta taaaagggtt aaaaaaaaaa 12600aaaaaaaa 12608952914DNAHomo sapiens 95gatttcagtt gaaagatgtg tttttgtgag tagagcaccg cagaagaact gaagactgtt 60gtgtgctccc cgcagaaggg gctaccatga tcctttcctc ctataacacc atccagtcgg 120ttttctgttg ctgctgttgc tgttcagtgc agaagcgaca aatgagaaca cagataagcc 180tgagcacaga tgaagagctt ccagaaaaat acacccagcg tcgcaggccg tggctcagcc 240aattgtcaaa taagaagcaa tccaacacgg gccgtgtgca gccgtcaaaa cgaaagccac 300tgcctcccct cccaccctct gaggttgctg aagagaagat ccaagtcaag gcactttatg 360attttctgcc cagagaaccc tgtaatttag ccttaaggag agcagaagaa tacctgatac 420tggagaaata caatcctcac tggtggaagg caagagaccg tttggggaat gaaggcttaa 480tcccaagcaa ctatgtgact gaaaacaaaa taactaattt agaaatatat gagtggtacc 540atagaaacat taccagaaat caggcagaac atctattgag acaagagtct aaagaaggtg 600catttattgt cagagattca agacatttag gatcctacac aatttccgta tttatgggag 660ctagaagaag tacggaggct gccataaaac attatcagat aaaaaagaat gactcaggac 720agtggtatgt ggctgaaaga cacgcctttc aatcaatccc tgagttaatc tggtatcacc 780agcacaatgc agccggtctc atgactcgtc tccgatatcc agttgggctg atgggcagtt 840gtttaccagc cacagctggg tttagctacg aaaagtggga gatagatcca tctgagttgg 900cttttataaa ggagattgga agcggtcagt ttggagtggt ccatttaggt gaatggcggt 960cacatatcca ggtagctatc aaggccatca atgaaggctc catgtctgaa gaggatttca 1020ttgaagaggc caaagtgatg atgaaattat ctcattcaaa gctagtgcaa ctttatggag 1080tctgtataca gcggaagccc ctttacattg tgacagagtt catggaaaat ggctgcctgc 1140ttaactatct cagggagaat aaaggaaagc ttaggaagga aatgctactg agtgtatgcc 1200aggatatatg tgaaggaatg gaatatctgg agaggaatgg ctatattcat agggatttgg 1260cggcaaggaa ttgtttggtc agttcaacat gcatagtaaa aatttcagac tttggaatga 1320caaggtacgt tttggatgat gagtatgtca gttcttttgg agccaagttc ccaatcaagt 1380ggtcccctcc tgaagttttt cttttcaata agtacagcag taaatctgat gtctggtcat 1440ttggagtttt aatgtgggaa gtttttacag aaggaaaaat gccttttgaa aataagtcaa 1500atttgcaagt cgtggaagct atttctgaag gcttcaggct atatcgccct cacctggcac 1560caatgtccat atatgaagtc atgtacagct gctggcatga gaaacctgaa ggccgcccta 1620catttgccga gctgctgcgg gctgtcacag agattgcgga aacctggtga ccggaaacag 1680aatgccaacc caaagagtca tcttgcaaaa ctgtcattta ttgtgaatat cttcaccata 1740tggggtcact tatggtgaat atctttcttc agagttgctg actcttgaaa acagtgcaaa 1800gatcacagtt tttaaaagtt ttaaaaattt aagaatattc acacaatcgt ttttctatgt 1860gtgagaggga tttgcacact cttatttttc tgtaaaatat ttcacatccc aaatgtgaag 1920aagtgaaaaa gacttcgcag cagtcttcat tgtggtgctc ttcatgatca tagccccagg 1980aacccttgag gttcttcttc acaaggctga gagtgcttcc ttcttgaaga cgagtgacat 2040tcatcacttc agtgatccat gcatagaata tgaaaataaa ttcttccaac tcatgggata 2100aaggggactc ccttgaagaa tttcatgttt ttgggctgta tagctcttta cagaaaatgc 2160acctttataa atcacatgaa tgttagtatt ctggaaatgt cttttgttaa tataatcttc 2220ccatgttatt taacaaattg tttttgcaca tatctgatta tattgaaagc agttttttgc 2280attcgagttt taaacactgt tataaaatgt agccaaagct cacctttgaa cagatcccgg 2340tgacattcta tttccaggaa aatccggaac ctgattttag ttctgtgatt ttacactttt 2400tacatgtgag attggacagt ttcagaggcc ttattttgtc atactaagtg tctcctgtaa 2460ttttcaggaa gatgatttgt tctttccaga agaggagaca aaagcaagat agccaaatgt 2520gacatcaagc tccattgttt cggaaatcca ggattttgaa ttcgagatga aacaaccagc 2580aatcacagtt aaatcttaac tttgcctgca ctctttgtag gaatgatcag aaatttatct 2640ttatcattct gagtgcttca ggagtacaat aggaagaaag atactggaga aagcactaat 2700gtaatcacca tgaagtctga caacaggagc ccattatttg cgtactgtcc caccctgtat 2760catggttctc tgggaacaag ctttatgatt ctcattagag tttatttgtt gattgtcagt 2820agttgcgact tttaaattat atttccccca ctcaaagaat ggtatcttta tatatcaatg 2880acattcaata aatgtgtatt atttctaatg agaa 2914962871DNAHomo sapiens 96gcccgcgcca gggtcctcgg agctgctctg gctgcgcgcg gagcgggctc cggagggaag 60tcccgagaca aagggaagcg ccgccgccgc cgccccgctc ggtcctccac ctgtccgcta 120cgctcgccgg ggctgcggcc gcccgaggga ctttgaacat gtcggggatc gccctcagca 180gactcgccca ggagaggaaa gcatggagga aagaccaccc atttggtttc gtggctgtcc 240caacaaaaaa tcccgatggc acgatgaacc tcatgaactg ggagtgcgcc attccaggaa 300agaaagggac tccgtgggaa ggaggcttgt ttaaactacg gatgcttttc aaagatgatt 360atccatcttc gccaccaaaa tgtaaattcg aaccaccatt atttcacccg aatgtgtacc 420cttcggggac agtgtgcctg tccatcttag aggaggacaa ggactggagg ccagccatca 480caatcaaaca gatcctatta ggaatacagg aacttctaaa tgaaccaaat atccaagacc 540cagctcaagc agaggcctac acgatttact gccaaaacag agtggagtac gagaaaaggg 600tccgagcaca agccaagaag tttgcgccct cataagcagc gaccttgtgg catcgtcaaa 660aggaagggat tggtttggca agaacttgtt tacaacattt ttgcaaatct aaagttgctc 720catacaatga ctagtcacct gggggggttg ggcgggcgcc atcttccatt gccgccgcgg 780gtgtgcggtc tcgattcgct gaattgcccg tttccataca gggtctcttc cttcggtctt 840ttgtattttt gattgttatg taaaactcgc ttttatttta atattgatgt cagtatttca 900actgctgtaa aattataaac ttttatactt gggtaagtcc cccaggggcg agttcctcgc 960tctgggatgc aggcatgctt ctcaccgtgc agagctgcac ttggcctcag ctggctgtat 1020ggaaatgcac cctccctcct gccgctcctc tctagaacct tctagaacct gggctgtgct 1080gcttttgagc ctcagacccc aggtcagcat ctcggttctg cgccacttcc tttgtgttta 1140tatggcgttt tgtctgtgtt gctgtttaga gtaaataaac tgtttatata aaggttttgg 1200ttgcattatt atcattgaaa gtgagaggag gcggcctccc agtgcccggc cctccccacc 1260cacctgcagc cccaccgcgg gccaggacca ggctctccat ctgcttcgga tgcacgcagg 1320ctgtgaggct ctgtcttgcc ctggatcttt gtaaacaggg ctgtgtacaa agtgctgctg 1380aggtttctgt gctccccgca tctgcgggct gtagagcgct gggcagctaa gatctgcata 1440ggtcgggatt ggcatcgaga ccctggcaac tgcaccggtg ccagctgtct tgggggccac 1500aaggccaggt ccagaccagg gctgggggct gcctgaggac tcctatccgg gcagcctgct 1560ggcgggggtt cccctcttca gtggccaggt cacagggatg gagctgcgct gtgcataggg 1620tgccacctca ggtgtctgtc ccttgtgtcc tcaggaggca gccttgctac cacccgtggc 1680aaacgccagg tgctttttct gggagagccc acagccgtgg ccctccaggg cttccccgac 1740ccttagcgcc aggtagaggg ccctgggcag cctgtgtctg gaattcttcg tcctgaggcc 1800acctgagtgt ggtctgtcct ggggaggctg tgcgcctcag cagccgtcct gacgctgagc 1860cctctgcaaa ggttgggccg gccaggcctc ttggggctgc ctgagccact gcaggaagtg 1920gcctggctgg gaagttgggt gccggtcacc tcccagcagg aaggcacagt ggacagagat 1980gggaagccct gggggacaca gcccggtgct cccagccctc caacctctgg ctcccaaccc 2040agtctcccca tcctagcgag cttggccctc ctcagtttcg tttcaagcct tggggctgga 2100gctggccctg ctgccctggc accccccggt ggctggagct gggtccccgt ggcccaagtg 2160cagggtccca agagggcagg gcggggctcc ccaaaggagc aaagaatgca gggagggcgg 2220tccagggccc tgggaagggg agctcggcac cctccaggtc cgtgtgggac tccagccgct

2280gttggctggg aatcgaagtt agaggtgact tccaaaggcc ccccgagccg gcagtgcccc 2340ccaccacccc tccagcgact ctgcggtgcc agtgccttgt tggcttttcc ggctacgcac 2400cctgcagtca ctgagctctc ggtctgacgt ctgatgtttg tggtttgttt ataacacggg 2460gccttacctg gggaattcag ctggtttgaa tatttgtagc ccgctcccag aatgtcttat 2520tttgtaatga ctgaactaca tttagtaata gttacacatg tatatggtta atacatatgg 2580aaattcaata tattttgtag ttaacgtatt ctgaagtaac ggatgtttct cgccaatcgt 2640agtgacttca gctaacgaaa tgttcttttg tagtaccacg gtcctcggcc taacgaagga 2700cgtgaacctt gtaagaggag agctctgaaa cgcggtcacc tttgtttagt ggaagggaaa 2760gtgtgttccc ggcatgaggt gcctcggaat tagtaaagaa ttgtgggcaa tggattaacc 2820actgtatcta agaatccacc attaaagcat ttgcacagac aaaaaaaaaa a 2871971892DNAHomo sapiens 97cgtgagcatg gtgaagagaa gacggagccc cgcgctggga gaggaacgct tcagtccgag 60ttccattctg cacccaaggc tccccttggt cctcctggga accagggtgc cccttagtgg 120tggtggccca ggagaacccg accaaggcag gagcgccccc tcctggaaga gcctcgcttc 180aacgcatcat cattcccggc cggcagcagg ggcgacgcca gcaaggcctg cgactcagag 240ccagcttggc ccgttcgccc cgccccttcc cggtgtccgc cccgcccctt tcccggtgtc 300cgccccgcct ccttcccggt gtccgccccg cccccttccc tgtgtccgcc ccgccccctt 360ccctgtgtcc gccctgcccg cttcactgtg gtcctgcctc tgggtggtgc cggggcgggg 420ggtgggagcc cggggcccgc gcaggcggag atgtcgccca atgggaaggg tcggtcggga 480agggggtggg cgcaggcggg tgggcgggaa gaacgctgga ggttgattgg cggtcttgcc 540ggccagtgaa gccagggcat gggcggggcg cggctcggag cgcgaaacat ggcggggcag 600gacgctggct gcggccgtgg cggcgacgac tactcagagg acgagggcga cagcagcgtg 660tccagggcgg ctgtggaggt gttcgggaag ctgaaggacc taaactgccc cttcctcgag 720ggtctgtata tcacagagcc aaagacaatt caggaactgc tgtgcagccc ctcagagtac 780cgcttggaga tcctagagtg gatgtgtacc cgggtctggc cctcactgca ggacaggttc 840agctcactga aaggggtccc aacagaggtg aagatccaag aaatgacgaa gctgggccac 900gagctgatgc tgtgtgcgcc agatgaccag gagctcctca agggctgtgc ctgcgcccag 960aagcagctac acttcatgga ccagttgctc gataccatcc ggagcctgac cattgggtgc 1020tccagttgct cgagcctgat ggagcacttc gaggacacca gggagaagaa cgaggccttg 1080ctgggggagc tcttctctag cccccacctg cagatgctcc tgaatccaga gtgcgacccg 1140tggcccctgg acatgcagcc cctcctcaac aagcagagtg atgactggca gtgggccagt 1200gcctctgcca agtccgagga ggaggagaag ctggcggagc ttgccaggca gctgcaggag 1260agtgctgcca agttgcacgc gcttagaacg gagtactttg cacagcatga gcaaggggct 1320gctgcgggcg cagccgacat cagcacccta gaccagaagc tgcgtctggt cacttccgac 1380ttccaccagc taatcttggc ttttctccaa gtctacgacg acgagctggg cgagtgctgc 1440cagcgcccag gccctgacct ccacccgtgc ggccccatca tccaggccac gcaccagaat 1500ctgacttcct acagccaact gctgcaagtg gtcatggcag ttgctgacac ctctgcgaag 1560gccgtggaga ccgtgaagaa gcagcaaggc gagcagatct gctggggtgg cagcagctcc 1620gtcatgagtc tagctaccaa gatgaatgaa ctaatggaga aatagaaagt cttcagtgat 1680ggcctacgcc aaagcacagg atggggcggg caggaagccc tctcccaaga tcgagttggc 1740cgaggatgga tgattgtggc agcagaagcc gttgcagccc cacgttgtgc tctaggcagg 1800gacctttggc ccctttgggg agggagagac agacgggcgg tttgacttgg acacaaagaa 1860agccttggtt tctaagcaaa aaaaaaaaaa aa 1892983374DNAHomo sapiens 98ctgagactgg acctgaggag acctcagcct cggtgctcgg gccgccccgc ctctgccgga 60aagtccgcgc cgccgctgcc gccaccgtcc gcagcccgag cgccccggag ccgcaggccg 120ccgccgcgca gagacgccgc ggctgcgact aggcgcgccc agccgcacgt ggcggacccg 180cccccaggcc cgcagtgtcc tggaccccgc aggcctccgc tctcctgtcc tcggccccgt 240ccccagggcc gcgatgagct tcctgagccg acagcagccg ccgccacccc gccgcgccgg 300ggcggcctgc accttgcggc agaagctgat cttctcgccc tgcagcgact gtgaggagga 360ggaagaagag gaggaggagg agggcagcgg ccacagcacc ggggaggact cggcctttca 420agagcccgac tcgccgctgc cgcccgcgcg gagccccacg gagcccgggc ccgagcgccg 480ccgctcgccc gggccggccc ccggcagccc cggcgagctg gaggaggacc tgttgctgcc 540cggcgcctgc ccgggcgcgg acgaggcggg cggtggggcg gagggcgact cgtgggagga 600ggagggcttc ggctcctcgt cgccggtcaa gtcgccggcg gccccctact tcctgggtag 660ctctttctcg ccggtgcgct gcggcggccc aggagatgcg tcgccgcggg gttgcggggc 720gcgccgggcg ggcgaaggcc gccgctcgcc gcggccggac cacccgggca ccccgccaca 780caagaccttc cgcaagctgc gactcttcga caccccgcac acgcccaaga gtttgctctc 840caaagctcgg ggaattgatt ccagctctgt taaactccgg ggtagttctc tcttcatgga 900tacagaaaaa tcaggaaaaa gggaatttga tgtgcgacag actcctcaag tgaatattaa 960tccttttact ccggattctt tgttgcttca ttcctcagga cagtgtcgtc gtagaaagag 1020aacgtattgg aatgattcct gtggtgaaga catggaagcc agtgattatg agcttgaaga 1080tgaaacaaga cctgctaaga gaattacaat tactgaaagc aatatgaagt cccggtatac 1140aacagaattt catgagctag agaaaatcgg ctctggagaa tttggttctg tatttaagtg 1200tgtgaagagg ctggatggat gcatttatgc cattaagcga tcaaaaaagc cattggcggg 1260ctctgttgat gagcagaacg ctttgagaga agtatatgct catgcagtgc ttggacagca 1320ttctcatgta gttcgatatt tctctgcgtg ggcagaagat gatcatatgc ttatacagaa 1380tgaatattgt aatggtggaa gtttagctga tgctataagt gaaaactaca gaatcatgag 1440ttactttaaa gaagcagagt tgaaggatct ccttttgcaa gttggccgag gcttgaggta 1500tattcattca atgtctttgg ttcacatgga tataaaacct agtaatattt tcatatctcg 1560aacctcaatc ccaaatgctg cctctgaaga aggagacgaa gatgattggg catccaacaa 1620agttatgttt aaaataggtg atcttgggca tgtaacaagg atctccagtc cacaagttga 1680agagggcgat agtcgttttc ttgcaaatga agttttacag gagaattata cccatctacc 1740aaaagcagat atttttgcgc ttgccctcac agtggtatgt gctgctggtg ctgaacctct 1800tccgagaaat ggagatcaat ggcatgaaat cagacagggt agattacctc ggataccaca 1860agtgctttcc caagaattta cagagttgct aaaagttatg attcatccag atccagagag 1920aagaccttca gcaatggcac tggtaaagca ttcagtattg ctgtccgctt ctagaaagag 1980tgcagaacaa ttacgaatag aattgaatgc cgaaaagttc aaaaattcac ttttacaaaa 2040agaactcaag aaagcacaga tggcaaaagc tgcagctgag gaaagagcac tcttcactga 2100ccggatggcc actaggtcca ccacccagag taatagaaca tctcgactta ttggaaagaa 2160aatgaaccgc tctgtcagcc ttactatata ctgagctact cctttcccac ctccccctga 2220acactgtgac aagaggaagc taggttgaaa tcactgatag aatccagttt gcaattactt 2280tctcgattgg tgtcagtagt tttactgatt aggactttta ttgtgaatta cagttgaaag 2340ctgtattttg atgattgcta tgtcaggctt tcatctaatc ttaccagtct gtcttctgta 2400ggatgtgtca ctgttggatg ttacaccagc ctttccaggg ttaaccactg tggtggtgtg 2460ctgcttatag tttgctgttg cattgtaata aaaggtgtct ttccctgtag tgacctgtaa 2520aaagtactca agggctttat tacagacata ccctcccttt gaaaagggac atgctaaaag 2580actcattact actcagcctt caatgtacct gtgtgtccat cttatatttc tttttttttt 2640aattgtgaat tagacttgta tatcccactg ggagcacttt gtaggcattg catgaaccat 2700gggatgatga ttctgtggag gtattgcctt gtgaatttgc tgctatttta gttttgtctt 2760tgctgtaaac ttgtagcatt aaacaatcat tgttgttaat aggtcttctt tttgaaacaa 2820ttatgtgaaa tgtatagctg cttttgatga aaagcagcta tttgcctttt tttttttttc 2880ctttgaactt tgaagctagt gcattggaaa aatgcaccct ttccctcctt tggaatgctg 2940tattaatgta gtataataat tactggtttt gtaacttgtt ctggtaatgt ccttcccgga 3000ctctttttaa atgtctcccc ctaagtttta tacttgattg tattattagt ctgtttttaa 3060atgttttgcc cggtttttct cttcaatatt tgtgtatata aaccgatctt cgtgatactg 3120tacatagctg tttgaaatgc cagaatgact tctgacattc caagtttttc acaaaatata 3180ttttatctgt gattagccat ttgactaata atactggcta acagatgttg aaaaaaattg 3240tctgtttgtt ttctcattaa ttttggtcta aaacatgttt gcacttgtct ttgacttgtg 3300ttttattaac attgattggc atattaaaag tcactctgag cttaccttaa ttgtctaaaa 3360aaaaaaaaaa aaaa 3374992108DNAHomo sapiens 99aatttctttt caatattagc ttattcccaa attggctaat gggtattttt aaagccatgc 60taaattaaag gaattcaatt ttctcactag tatttggtaa cacatgggag actatgtgtc 120atatccagaa gagttctgta catgaactgc atttaattgc tccgagagtc actggagctt 180tctttaatca gaatggaaat caggataagc tgaggtctta tagattggtg gtacttaagg 240cagaaaatta acaccgtgtt ttgtagctgt tagttggtag agggaaattc aggctaccgt 300cgcgaaacct gcaggttaag ttattttctc ctccctgctt ctgtaggttc acagcgttcc 360cttctgatag agctttttgt ctgtgttgta aagctctttg gctgagatgg atgacaaaga 420tattgacaaa gaactaaggc agaaattaaa cttttcctat tgtgaggaga ctgagattga 480agggcagaag aaagtagaag aaagcaggga ggcttcgagc caaaccccag agaagggtga 540agtgcaggat tcagaggcaa agggtacacc accttggact ccccttagca acgtgcatga 600gctcgacaca tcttcggaaa aagacaaaga aagtccagat cagattttga ggactccagt 660gtcacaccct ctcaaatgtc ctgagacacc agcccaacca gacagcagga gcaagctgct 720gcccagtgac agcccctcta ctcccaaaac catgctgagc cggttggtga tttctccaac 780agggaagctt ccttccagag gccctaagca tttgaagctc acacctgctc ccctcaagga 840tgagatgacc tcattggctc tggtcaatat taatcccttc actccagagt cctataaaaa 900attatttctt caatctggtg gcaagaggaa aataagagga gatcttgagg aagctggtcc 960agaggaaggc aagggagggc tgcctgccaa gagatgtgtt ttacgagaaa ccaacatggc 1020ttcccgctat gaaaaagaat tcttggaggt tgaaaaaatt ggggttggcg aatttggtac 1080agtctacaag tgcattaaga ggctggatgg atgtgtttat gcaataaagc gctctatgaa 1140aacttttaca gaattatcaa atgagaattc ggctttgcat gaagtttatg ctcacgcggt 1200gcttgggcat cacccccatg tggtacgtta ctattcctca tgggcagaag atgaccacat 1260gatcattcag aatgaatact gcaatggtgg gagtttgcaa gctgctatat ctgaaaacac 1320taagtctggc aatcattttg aagagccaaa actcaaggac atccttctac agatttccct 1380tggccttaat tacatccaca actctagcat ggtacacctg gacatcaaac ctagtaatat 1440attcatttgt cacaaggtgc aaagtgaatc ctctggagtc atagaagaag ttgaaaatga 1500agctgattgg tttctctctg ccaatgtgat gtataaaatt ggtgacctgg gccacgcaac 1560atcaataaac aaacccaaag tggaagaagg agatagtcgc ttcctggcta atgagatttt 1620gcaagaggat taccggcacc ttcccaaagc agacatattt gccttgggat taacaattgc 1680agtggctgca ggagcagagt cattgcccac caatggtgct gcatggcacc atatccgcaa 1740gggtaacttt ccggacgttc ctcaggagct ctcagaaagc ttttccagtc tgctcaagaa 1800catgatccaa cctgatgccg aacagagacc ttctgcagca gctctggcca gaaatacagt 1860tctccggcct tccctgggaa aaacagaaga gctccaacag cagctgaatt tggaaaagtt 1920caagactgcc acactggaaa gggaactgag agaagcccag caggcccagt caccccaggg 1980atatacccat tatggtgaca ctggggtctc tgggacccac acaggatcaa gaagcacaaa 2040acgcctggtg ggaggaaaga gtgcaaggtc ttcaagcttt acctcaggag agcgtgagcc 2100tctgcatt 210810010461DNAHomo sapiens 100ccggcccttc gcctctgggc gatgggcgac ctgtgaggcc ggtccccatc gctgggggcg 60cgtgtgggag gaggcggccg cccgagtgac cgggagccgg gccgcggcct tccctcgccc 120gcctcggccc ctcccactcc tctgccccgg ggccgccacc gcccgggcgt cggacctggt 180cccgtgctcg cggtgccgcc gccctctggg cctagcccgc ccagctcggc gagcggcggc 240agtgggagcc gcgtccgccg catccgcctc gactcggtgc cggcccctgg ccctcccctc 300atgactgcgg cgcctctgct gccaccgccc gcccggccgc cgctcgccgc aggatggatg 360cggaccgtgc ggcgctaacc cccgtggctc agctcccgaa tcgcccgcct tcgagccctc 420ctcgtgagcc gcagcagcct cggtgccagc ccccgccgca gctgggccca gcggtccgcc 480tgtccctcgt tgcggcttgt cggtgctgag tgaggcgtcg tccgggtcgg cgcgaacccg 540cccggccgcg gttccctgca gacctctgcg cgggcggctc ggcccttcac gcccttttcg 600ttcacgaatc cgagcccgct cgcctctctc cagcgaaccg accatgtctg gcggcgccgc 660agagaagcag agcagcactc ccggttccct gttcctctcg ccgccggctc ctgcccccaa 720gaatggctcc agctccgatt cctccgtggg ggagaaactg ggagccgcgg ccgccgacgc 780tgtgaccggc aggaccgagg agtacaggcg ccgccgccac actatggaca aggacagccg 840tggggcggcc gcgaccacta ccaccactga gcaccgcttc ttccgccgga gcgtcatctg 900tgactccaat gccactgcac tggagcttcc cggccttcct ctttccctgc cccagcccag 960catccccgcg gctgtcccgc agagtgctcc accggagccc caccgggaag agaccgtgac 1020cgccaccgcc acttcccagg tagcccagca gcctccagcc gctgccgccc ctggggaaca 1080ggccgtcgcg ggccctgccc cctcgactgt ccccagcagt accagcaaag accgcccagt 1140gtcccagcct agccttgtgg ggagcaaaga ggagccgccg ccggcgagaa gtggcagcgg 1200cggcggcagc gccaaggagc cacaggagga acggagccag cagcaggatg atatcgaaga 1260gctggagacc aaggccgtgg gaatgtctaa cgatggccgc tttctcaagt ttgacatcga 1320aatcggcaga ggctccttta agacggtcta caaaggtctg gacactgaaa ccaccgtgga 1380agtcgcctgg tgtgaactgc aggatcgaaa attaacaaag tctgagaggc agagatttaa 1440agaagaagct gaaatgttaa aaggtcttca gcatcccaat attgttagat tttatgattc 1500ctgggaatcc acagtaaaag gaaagaagtg cattgttttg gtgactgaac ttatgacgtc 1560tggaacactt aaaacgtatc tgaaaaggtt taaagtgatg aagatcaaag ttctaagaag 1620ctggtgccgt cagatcctta aaggtcttca gtttcttcat actcgaactc cacctatcat 1680tcaccgcgat cttaaatgtg acaacatctt tatcaccggc cctactggct cagtcaagat 1740tggagacctc ggtctggcaa ccctgaagcg ggcttctttt gccaagagtg tgataggtac 1800cccagagttc atggcccctg agatgtatga ggagaaatat gatgaatccg ttgacgttta 1860tgcttttggg atgtgcatgc ttgagatggc tacatctgaa tatccttact cggagtgcca 1920aaatgctgca cagatctacc gtcgcgtgac cagtggggtg aagccagcca gttttgacaa 1980agtagcaatt cctgaagtga aggaaattat tgaaggatgc atacgacaaa acaaagatga 2040aagatattcc atcaaagacc ttttgaacca tgccttcttc caagaggaaa caggagtacg 2100ggtagaatta gcagaagaag atgatggaga aaaaatagcc ataaaattat ggctacgtat 2160tgaagatatt aagaaattaa agggaaaata caaagataat gaagctattg agttttcttt 2220tgatttagag agagatgtcc cagaagatgt tgcacaagaa atggtagagt ctgggtatgt 2280ctgtgaaggt gatcacaaga ccatggctaa agctatcaaa gacagagtat cattaattaa 2340gaggaaacga gagcagcggc agttggtacg ggaggagcaa gaaaaaaaaa agcaggaaga 2400gagcagtctc aaacagcagg tagaacaatc cagtgcttcc cagacaggaa tcaagcagct 2460cccttctgct agcaccggca tacctactgc ttctaccact tcagcttcag tttctacaca 2520agtagaacct gaagaacctg aggcagatca acatcaacaa ctacagtacc agcaacccag 2580tatatctgtg ttatctgatg ggacggttga cagtggtcag ggatcctctg tcttcacaga 2640atctcgagtg agcagccaac agacagtttc atatggttcc caacatgaac aggcacattc 2700tacaggcaca gtcccagggc atataccttc tactgtccaa gcacagtctc agccccatgg 2760ggtatatcca ccctcaagtg tggcacaggg gcagagccag ggtcagccat cctcaagtag 2820cttaacaggg gtttcatctt cccaacccat acaacatcct cagcagcagc agggaataca 2880gcagacagcc cctcctcaac agacagtgca gtattcactt tcacagacat caacctccag 2940tgaggccact actgcacagc cagtgagtca gcctcaagct ccacaagtct tgcctcaagt 3000atcagctgga aaacagcttc cagtttccca gccagtacca actatccaag gcgaacctca 3060gatcccagtt gcgacacaac cctcggttgt tccagtccac tctggtgctc atttccttcc 3120agtgggacag ccgctcccta ctcccttgct ccctcagtac cctgtctctc agattcccat 3180atcaactcct catgtgtcta cggctcagac aggtttctca tcccttccca tcacaatggc 3240agctggcatt actcagcctc tgctcacgtt ggcttcatct gctacaacag ctgcgatccc 3300gggggtatca actgtggttc ctagtcagct tccaaccctt ctgcagcctg tgactcagct 3360gccaagtcag gttcacccac agctcctaca accagcagtt cagtccatgg gaataccagc 3420taaccttgga caagctgctg aggttccact ttcctctgga gatgttctgt accagggctt 3480cccacctcga ctgccaccac agtacccagg agattcaaat attgctccct cttccaacgt 3540ggcttctgtt tgcatccatt ctacagtcct atcccctccc atgccgacag aagtactggc 3600tacacctggg tactttccca cagtggtgca gccttatgtg gaatcaaatc ttttagttcc 3660tatgggtggt gtaggaggac aggttcaagt gtcccagcca ggagggagtt tagcacaagc 3720ccccactaca tcctcccagc aagcagtttt ggagagtact cagggagtct ctcaggttgc 3780tcctgcagag ccagttgcag tagcacagac ccaagctacc cagccgacca ctttggcttc 3840ctctgtagac agtgcacatt cagatgttgc ttcaggtatg agtgatggca atgagaacgt 3900cccatcttcc agtggaaggc atgaaggaag aactacaaaa cggcattacc gaaaatctgt 3960aaggagtcgc tctcgacatg aaaaaacttc acgcccaaaa ttaagaattt tgaatgtttc 4020aaataaagga gaccgagtag tagaatgtca attagagact cataatagga aaatggttac 4080attcaaattt gacctagatg gtgacaaccc cgaggagata gcaacaatta tggtgaacaa 4140tgactttatt ctagcaatag agagagagtc gtttgtggat caagtgcgag aaattattga 4200aaaagctgat gaaatgctca gtgaggatgt cagtgtggaa ccagagggtg atcagggatt 4260ggagagtcta caaggaaagg atgactatgg cttttcaggt tctcagaaat tggaaggaga 4320gttcaaacaa ccaattcctg cgtcttccat gccacagcaa ataggcattc ctaccagttc 4380tttaactcaa gttgttcatt ctgcgggaag gcggtttata gtgagtcctg tgccagaaag 4440ccgattacga gaatcaaaag ttttccccag tgaaataaca gatacagttg ctgcctctac 4500agctcagagc cctggaatga acttgtctca ctctgcatca tcccttagtc tacaacaggc 4560cttttctgaa cttagacgtg cccaaatgac agaaggaccc aacacagcac ctccaaactt 4620tagtcataca ggaccaacat ttccagtagt acctcctttc ttaagtagca ttgctggagt 4680cccaaccaca gcagcagcca cagcaccagt ccctgcaaca agcagccctc ctaatgacat 4740ttccacatca gtaattcagt ctgaggttac agtgcccact gaagagggga ttgctggagt 4800tgccaccagc acaggtgtgg taacttcagg tggtctcccc ataccacctg tgtctgaatc 4860accagtactt tccagcgtag tttcaagtat cacaatacct gcagttgtct caatatctac 4920tacatccccg tcacttcaag tccccacatc cacatctgag atcgttgttt ctagtacagc 4980actgtatcct tcagtaacag tttcagcaac ttcagcctct gcagggggca gtactgctac 5040cccaggtcct aagcctccag ctgtagtatc tcagcaggca gcaggcagca ctactgtggg 5100agccacatta acatcagttt ctaccaccac ttcattccca agcacagctt cacagctgtg 5160cattcagctt agcagcagta cttctactcc tactttagct gaaaccgtgg tagttagcgc 5220acactcacta gataagacat ctcatagcag tacaactgga ttggctttct ccctctctgc 5280accatcttcc tcttcctctc ctggagcagg agtgtctagt tatatttctc agcctggtgg 5340gctgcatcct ttggtcattc catcagtgat agcttctact cctattcttc cccaagcagc 5400aggacctact tctacacctt tattacccca agtacctagt atcccaccct tggtacagcc 5460tgttgccaat gtgcctgctg tacagcagac actaattcat agtcagcctc aaccagcttt 5520gcttcccaac cagccccata ctcattgtcc tgaagtagat tctgatacac aacccaaagc 5580tcctggaatt gatgacataa agactctaga agaaaagctg cggtctctgt tcagtgaaca 5640cagctcatct ggagctcagc atgcctctgt ctcactggag acctcactag tcatagagag 5700cactgtcaca ccaggcatcc caactactgc tgttgcacca agcaaactcc tgacttctac 5760cacaagtact tgcttaccac caaccaattt accactagga acagttgctt tgccagttac 5820accagtggtc acacctgggc aagtttctac cccagtcagc actactacat caggagtgaa 5880acctggaact gctccctcca agccacctct aactaaggct ccggtgctgc cagtgggtac 5940tgaacttcca gcaggtactc tacccagcga gcagctgcca ccttttccag gaccttctct 6000aacccagtcc cagcaacctc tagaggatct tgatgctcaa ttgagaagaa cacttagtcc 6060agagatgatc acagtgactt ctgcggttgg tcctgtgtcc atggcggctc caacagcaat 6120cacagaagca ggaacacagc ctcagaaggg tgtttctcaa gtcaaagaag gccctgtcct 6180agcaactagt tcaggagctg gtgtttttaa gatgggacga tttcaggttt ctgttgcagc 6240agacggtgcc cagaaagagg gtaaaaataa gtcagaagat gcaaagtctg ttcattttga 6300atccagcacc tcagagtcct cagtgctatc aagtagtagt ccagagagta ccttggtgaa 6360accagagccg aatggcataa ccatccctgg tatctcttca gatgtgccag agagtgccca 6420caaaactact gcctcagagg caaagtcaga cactgggcag cctaccaagg ttggacgttt 6480tcaggtgaca actacagcaa acaaagtggg tcgtttctct gtatcaaaaa ctgaggacaa 6540gatcactgac acaaagaaag aaggaccagt ggcatctcct ccttttatgg atttggaaca 6600agctgttctt cctgctgtga taccaaagaa agagaagcct gaactgtcag agccttcaca 6660tctaaatggg ccgtcttctg acccggaggc cgctttttta agtagggatg tggatgatgg 6720ttccggtagt ccacactcgc cccatcagct gagctcaaag agccttccta gccagaatct 6780aagtcaaagc cttagtaatt catttaactc ctcttacatg agtagcgaca atgagtcaga 6840tatcgaagat gaagacttaa agttagagct

gcgacgacta cgagataaac atctcaaaga 6900gattcaggac ctgcagagtc gccagaagca tgaaattgaa tctttgtata ccaaactggg 6960caaggtgccc cctgctgtta ttattccccc agctgctccc ctttcaggga gaagacgacg 7020acccactaaa agcaaaggca gcaaatctag tcgaagcagt tccttgggga ataaaagccc 7080ccagctttca ggtaacctgt ctggtcagag tgcagcttca gtcttgcacc cccagcagac 7140cctccaccct cctggcaaca tcccagagtc cgggcagaat cagctgttac agccccttaa 7200gccatctccc tccagtgaca acctctattc agccttcacc agtgatggtg ccatttcagt 7260accaagcctt tctgctccag gtcaaggaac cagcagcaca aacactgttg gggcaacagt 7320gaacagccaa gccgcccaag ctcagcctcc tgccatgacg tccagcagga agggcacatt 7380cacagatgac ttgcacaagt tggtagacaa ttgggcccga gatgccatga atctctcagg 7440caggagagga agcaaagggc acatgaatta cgagggccct ggaatggcaa ggaagttctc 7500tgcacctggg caactgtgca tctccatgac ctcgaacctg ggtggctctg cccccatctc 7560tgcagcatca gctacctctc taggtcactt caccaagtct atgtgccccc cacagcagta 7620tggctttcca gctaccccat ttggcgctca atggagtggg acgggtggcc cagcaccaca 7680gccacttggc cagttccaac ctgtgggaac tgcctccttg cagaatttca acatcagcaa 7740tttgcagaaa tccatcagca accccccagg ctccaacctg cggaccactt agacctagag 7800acattaactg aatagatctg ggggcaggag atggaatgct gagggggtgg gtgggggtgg 7860gaagtagcct atatactaac tactagtgct gcatttaact ggttatttct tgccagaggg 7920gaatgttttt aatactgcat tgagccctca gaatggagag tctcccccgc tccagttatt 7980ggaatgggag aggaaggaaa gaacagcttt tttgtcaagg ggcagcttca gaccatgctt 8040tcctgtttat ctatactcag taatgaggat gagggctagg aaagtcttgt tcataaggaa 8100gctggagaac tcaatgtaaa atcaaaccca tctgtaattt cgagtgggtg gagctcttgc 8160ttttggtaca tgccctgaat ccctcactcc ctcaagaatc cgaaccacag gacaaaaacc 8220acctactggg ctctctccta ccctgccctc ctcccttttt tttacccctc tcttttttat 8280tttttctttg ctctttagaa cccagtgaaa aataccaggg tactggggtg caactctttc 8340ttatgatagg tcattagtgc tttaagcaaa agatattagc agctttgact gcagcattag 8400caattaggaa aaaaaaaaaa ttaagttccc tgcggacatg taactttgcc atcagttttg 8460atgtggaaac actgtgatat ataaaatgtt gttggacaac agtagtttta agagtaaaat 8520atgaaacgtt taaaaagttc caaaaaaagc tagctctgtc ctttacttat tgagacactt 8580taactttttc ctttgtattt ccattgtatt agataaataa atgtgaatgt aaaattgtat 8640aaattactgt acttgaatac ttctgtttcc cagtgttgct tgctggacat tttagtgcct 8700tggacttcta ttgcttctgc cattagcatc aacttaccag accccagatc aataaagggc 8760atgtggaagg aaatcgtagg tccatgtgac cccagcagtc cagcagtggt tatgccaaag 8820ggaaattgaa aaagtatttt tttaagtcat tcaacaactt tgtctagagc aggtgtaaga 8880tgagtagggt gggaagttag gttggcatca gtggttaaaa acagaaagtt ctgtttcggg 8940aatagtgagg agggggtgtt gtaacaaaat tggacaactt aaaagaatgg tgtgtgctgg 9000gtgaaagaca aagactaaag aatgaggaaa caaacgtgat gcctggccag tgactgtcat 9060ataaaccttt cttatttgag ctaggcttga acagacgtga cctagaagaa actgaacata 9120aagagaaggg ggtggggggc tagttttcaa gttggggaac ctgatagtga aaagtcacag 9180atggagaaaa ttgctctcag aaaaactgtt tggattgctt tcctcttgtt gcacatgtac 9240catgcatttc tcagcttggg gtactacatt ttgtggaaag ttaatctatc tatctttcca 9300catctgaatt aatcattcta ggaaagaata cttattccta ctcatttcct ttatgatgtc 9360caaatggttg caggatcata atctattgtg ccacctttat ttctagaagt acaactaata 9420tgttcacatt ttcaaataaa taatactccc cgtaagtaat aactgcaacc aatcagtgtt 9480attcagtgct atgcctcctt gtaatgggta gttattaatt attttcagag ctttccggaa 9540atactgtcct aactggctat gtttaggatc tttgttatct ctgaagacaa agaaagaagc 9600taggactctt aattttgggg tgcttcttga ctcttagttg ggaaactgaa aatatttcca 9660accttttacc cacgtcaatg gcatattctg ggaatcacca ccaccaccac cactaccaca 9720gaaagaggct ggaggctcct gtaccctgtt cattccttaa gggccctgct tcccttagta 9780agtaagtaag ttggtctacg gccctaaata tgcaaatgag agctgaaggt ttttaaaagg 9840tagaaaggaa aagggcaagg gcttccaccc ctgctttaaa atgatttatt tattctctgc 9900ttgtatttct tgtggagaga gtaaggatag aaccaacaag gggctgagta gctgagaaag 9960gggccaccca agagtgaaac atactttata ccagaggagc agtggagcct catgcagcac 10020attatcattt gttatttggg tttaataata attttgacat cttttcactc atacacaaaa 10080aaagtcagaa ctggtgttat ttactgttga tttcatcctc ctgtgtatga aataacaagc 10140ctagaggaat gaactagtgc tactgaactg tttaaattat ttttgtgtta atagtacact 10200ttgagtatct ttttccacat taaaaacttt ctgaattata aatgttttcc ttacattatt 10260taacaatgta cactgttaaa aataaaaata aaaattcaaa ctttgggggt ttctcagcag 10320ccgttaattg tacattttgc actaactctg ggtgttgcgc ttcttgtaag attgcgcttt 10380gtgcttcagt ttgttacctt tgtagactta tttaatgaaa ccattcaaat aaaccaaact 10440tgcttttgtt gaaaaaaaaa a 104611011712DNAHomo sapiens 101ttgggtacag tgcaagatgc ttgggtgatg ggtgcactga aatcaccact aaagaactag 60tttcccaaaa actattgaaa aaaaaagtgg cagctaaatt aggccctaaa gaatggttag 120gattttcaca tgtaaagatt acaggccggg catggtgtct cacgcctgcc attttagcac 180tttgggaagc caaggcagga ggactgcttg agcccagaag ttcgagacca gcttgggcaa 240catggcaaaa cttcgtctct acaaaaaata caaagaatta gtcaggcgtg gtagtgtgca 300cctgtagttc cagctactca ggaggctgag gtgggaggat cacctgagcc ccaggaggtc 360aaggctgcag tgagctgaaa tcacgccact atactctagc ctgagcaaca gagggagacc 420ctatctcgaa aaacaacaac aacaaacatt acagatggag gtaactgtac agaagtatgg 480aggttgaaag aaagcactat gtctaaagca gggtttctca atctcagcac cgctaccatt 540ttgggcctga taattctgtt gtggggggaa gggggggttt gcctgcacat ttctgtacac 600tgtaggaggt tcagcagtat acctggcctc tacccactag atgtcaagca gtagccccca 660ggttgtaacc accaaaaaag tctgtagaca ttgtcagatg tcccctggtg agtggcggta 720cagggcaata tctcctctga ctgagaacct ctggcctttc taggaaagaa attaaaatat 780atttgttgtc atgtcaaaag aagtgtaaag aggctactac ttgctctatg tataatgcaa 840aggataccta gtcaagttct ttcttggagg aaataactat cagaaagcca cagcagtaca 900tgattttatg aatgaaatca atgtctctat gactcttctg agggaagcta aaacaattct 960tattctggaa aaccctgtat agtcaagaga gttaagcaaa acacacaaca cattacaagc 1020ttttatgtaa aagtaatttt accttgtctt gctgtgtatt cattgtcttc aattaacctt 1080gctaaaccaa agtctgctat tttgcacaca agattttctc ctacaagaat attagcagcc 1140cgaagatctc ggtgaatata gttcattctt tcaatatatg ccataccatc agcaatcttg 1200gaaagagaaa aacaaaaaac acaagacata cgatacaaag ggaagcagag agaagacaat 1260tatggttaat atcaaattgt gtcactgaaa atcatattat tttagaagga gatgatggta 1320acagggtata gtctagaaga taacaggaaa accagaaaac ataataaaaa tgcaggctaa 1380attcagattt caaaaatcta acactggctg ggtgcggtgg cccacaccta taatcccatt 1440aatttgggag gccgaggcag gtggatcact tgaggtcatg agttcgagat cagcctggcc 1500aacacggtga aaccctgtct ctattaaaaa tacaaaaatt agccgggcct ggtggcaggt 1560gcctgtaatc ccagctacag gggaggctga ggcaggagaa tcatttgaac ctgggaggtg 1620gaggttgcag tgagctgaga ttgtaccact gcactccagc ctgggcaaca gattgagact 1680gtgtctcaaa gcaaaaaaaa aaaaaaaaaa aa 1712

Claims

1. A method for inhibiting the growth and/or proliferation of a MYC-driven tumor cell comprising the step of contacting the tumor cell with an inhibitor that inhibits a gene function of at least one of the genes listed in Table 2.

2. The method of claim 1, wherein the MYC-driven tumor cell is at least one of the following: a neuroblastoma tumor, a metastatic neuroblastoma tumor, a medulloblastoma, a lymphoma, a rhabdomyosarcoma, a melanoma, a lung cancer, a liver cancer, a breast cancer, a colon cancer, a prostate cancer, an ovarian cancer, or a Burkitt's lymphoma.

3. The method of claim 1, wherein the tumor cell is contacted in vitro.

4. The method of claim 1, wherein the tumor cell is contacted in vivo in a mammalian subject.

5. The method of claim 1, wherein the inhibitor is a small molecule inhibitor that inhibits the function of the gene product.

6. The method of claim 1, wherein the inhibitor interferes with the transcription of mRNA from the gene.

7. The method of claim 1, wherein the inhibitor interferes with production or expression of the functional gene product of the gene.

8. The method of claim 1, wherein the gene is selected from the genes listed in Table 1.

9. The method of claim 1, wherein the gene is selected from the group consisting of ALDOA, CECR2, IGF2R, PAK6, PES1, RAD21, REVJL, SUV39H1, TIE1, and CRKRS.

10. A method of treating a subject suffering from a tumor comprising MYC-driven tumor cells, comprising administering to the subject an amount of a composition comprising an inhibitor that inhibits a gene function of at least one of the genes listed in Table 2 and is effective to inhibit the growth and/or proliferation of the MYC-driven tumor cells.

11. The method of claim 10, wherein the MYC-driven tumor cell is at least one of the following: a neuroblastoma tumor, a metastatic neuroblastoma tumor, a medulloblastoma, a lymphoma, a rhabdomyosarcoma, a melanoma, a lung cancer, a liver cancer, a breast cancer, a colon cancer, a prostate cancer, an ovarian cancer, or a Burkitt's lymphoma.

12. The method of claim 10, wherein the inhibitor is a small molecule inhibitor that inhibits the function of the gene product.

13. The method of claim 10, wherein the inhibitor interferes with the transcription of mRNA from the gene.

14. The method of claim 10, wherein the inhibitor interferes with production or expression of the functional gene product of the gene.

15. The method of claim 10, wherein the gene is selected from the genes listed in Table 1.

16. The method of claim 10, wherein the gene is selected from the group consisting of ALDOA, CECR2, IGF2R, PAK6, PES1, RAD21, REVJL, SUV39H1, TIE1, and CRKRS.

Images