Zannettino
Andrew Zannettino, Highbury AU
Patent application number | Description | Published |
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20100330045 | Mesenchymal precursor cell - A method of enriching mesenchymal precursor cells including the step of enriching for cells based on at least two markers. The markers may be either i) the presence of markers specific for mesenchymal precursor cells, ii) the absence of markers specific for differentiated mesenchymal cells, or iii) expression levels of markers specific for mesenchymal precursor cells. The method may include a first solid phase sorting step utilising MACS recognising expression of the antigen to the STRO-1 Mab, followed by a second sorting step utilising two colour FACS to screen for the presence of high level STRO-1 antigen expression as well as the expression of VCAM-1. | 12-30-2010 |
20120276553 | MESENCHYMAL PRECURSOR CELL - A method of enriching mesenchymal precursor cells including the step of enriching for cells based on at least two markers. The markers may be either i) the presence of markers specific for mesenchymal precursor cells, ii) the absence of markers specific for differentiated mesenchymal cells, or iii) expression levels of markers specific for mesenchymal precursor cells. The method may include a first solid phase sorting step utilising MACS recognising expression of the antigen to the STRO-1 Mab, followed by a second sorting step utilising two colour FACS to screen for the presence of high level STRO-1 antigen expression as well as the expression of VCAM-1. | 11-01-2012 |
Andrew Zannettino, South Australia AU
Patent application number | Description | Published |
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20120082649 | PERIVASCULAR MESENCHYMAL PRECURSOR CELLS - Mesenchymal precursors cells have been isolated from perivascular niches from a range of tissues utilizing a perivascular marker. A new mesenchymal precursor cell phenotype is described characterized by the presence of the perivascular marker 3G5, and preferably also alpha smooth muscle actin together with early developmental markers such as MUC 18, VCAM-1 and STRO-1 | 04-05-2012 |
Andrew Christopher William Zannettino, South Australia AU
Patent application number | Description | Published |
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20080260694 | Multipotential Expanded Mesenchymal Precursor Cell Progeny (Memp) and Uses Thereof - The invention relates to multipotential expanded mesenchymal precursor progeny (MEMP's), characterised by the early developmental markers STRO-1 | 10-23-2008 |
20090029912 | Method of enhancing proliferation and/or survival of mesenchymal precursor cells (mpc) - The present invention relates to methods of enhancing proliferation and/or survival of mesenchymal precursor cells (MPC) and/or progeny derived therefrom in vitro or in vivo comprising exposing the MPC or progeny to SDF-1 or analog thereof. The invention also relates to compositions comprising isolated MPCs or progeny derived therefrom and SDF-1 or analogues thereof. The present invention also relates to using such methods and compositions for ex vivo or in vivo bone formation in mammals. | 01-29-2009 |
20090074728 | Isolation of adult multipotential cells by tissue non-specific alkaline phosphatase - The present invention relates to the use of tissue non-specific alkaline phosphatase (TNAP) as a marker for identifying and/or isolating adult multipotential cells. The present invention also relates to cell populations enriched by methods of the present invention and therapeutic uses of these cells. | 03-19-2009 |
Andrew Christopher William Zannettino, Highbury AU
Patent application number | Description | Published |
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20110223668 | Method of enhancing proliferation and/or survival of mesenchymal precursor cells (MPC) - The present invention relates to methods of enhancing proliferation and/or survival of mesenchymal precursor cells (MPC) and/or progeny derived therefrom in vitro or in vivo comprising exposing the MPC or progeny to SDF-1 or analog thereof. The invention also relates to compositions comprising isolated MPCs or progeny derived therefrom and SDF-1 or analogues thereof. The present invention also relates to using such methods and compositions for ex vivo or in vivo bone formation in mammals. | 09-15-2011 |
20130209417 | ISOLATION OF ADULT MULTIPOTENTIAL CELLS BY TISSUE NON-SPECIFIC ALKALINE PHOSPHATASE - The present invention relates to the use of tissue non-specific alkaline phosphatase (TNAP) as a marker for identifying and/or isolating adult multipotential cells. The present invention also relates to cell populations enriched by methods of the present invention and therapeutic uses of these cells. | 08-15-2013 |
20140178991 | Multipotential Expanded Mesenchymal Precursor Cell Progeny (MEMP) and Uses Thereof - The invention relates to multipotential expanded mesenchymal precursor progeny (MEMP's), characterised by the early developmental markers STRO-1 | 06-26-2014 |
20150072422 | METHOD OF ENHANCING PROLIFERATION AND/OR SURVIVAL OF MESENCHYMAL PRECURSOR CELLS (MPC) - The present invention relates to methods of enhancing proliferation and/or survival of mesenchymal precursor cells (MPC) and/or progeny derived therefrom in vitro or in vivo comprising exposing the MPC or progeny to SDF-1 or analog thereof. The invention also relates to compositions comprising isolated MPCs or progeny derived therefrom and SDF-1 or analogues thereof. The present invention also relates to using such methods and compositions for ex vivo or in vivo bone formation in mammals. | 03-12-2015 |