Patent application number | Description | Published |
20090123414 | Il-15 Antigen Arrays And Uses Thereof - The present invention is related to the fields of molecular biology, virology, immunology and medicine. The invention provides a composition comprising an ordered and repetitive antigen array, wherein the antigen is an IL-15 protein, an IL-15 mutein or an IL-15 fragment. More specifically, the invention provides a composition comprising a virus-like particle, and at least one IL-15 protein, IL-15 mutein or at least one IL-15 fragment linked thereto. The invention also provides a process for producing the composition. The compositions of the invention are useful in the production of vaccines for the treatment of inflammatory and chronic autoimmune diseases. The composition of the invention efficiently induces immune responses, in particular antibody responses. Furthermore, the compositions of the invention are particularly useful to efficiently induce self-specific immune responses within the indicated context. | 05-14-2009 |
20100111995 | Antigen conjugates and uses thereof - The present invention is in the fields of medicine, public health, immunology, molecular biology and virology. The invention provides composition comprising a virus-like particle (VLP) linked to at least one antigen of the invention, wherein said antigen of the invention is CCR5 of the invention, gastrin of the invention, CXCR4 of the invention, CETP of the invention or C5a of the invention. The invention also provides a process for producing the composition. The compositions of this invention are useful in the production of vaccines, in particular, for the treatment of diseases in which the antigen of the invention mediates, or contributes to the condition, particularly for the treatment of AIDS, gastrointestinal cancers, coronary heart diseases or inflammatory diseases. Moreover, the compositions of the invention induce efficient immune responses, in particular antibody responses. Furthermore, the compositions of the invention are particularly useful to efficiently induce self-specific immune responses within the indicated context. | 05-06-2010 |
20100303846 | Immunostimulatory Nucleic Acid Packaged Particles for the Treatment of Hypersensitivity - The application is related to compositions and methods for the treatment of hypersensitivity, wherein the compositions comprise a particle packaged with immunostimulatory nucleic acids. The compositions of the invention are particularly useful in the treatment of atopic eczema, asthma and IgE-mediated allergy (type I allergy), especially pollen allergy and house dust allergy. | 12-02-2010 |
20140056933 | IMMUNOSTIMULATORY NUCLEIC ACID PACKAGED PARTICLES FOR THE TREATMENT OF HYPERSENSITIVITY - The application is related to compositions and methods for the treatment of hypersensitivity, wherein the compositions comprise a particle packaged with immunostimulatory nucleic acids. The compositions of the invention are particularly useful in the treatment of atopic eczema, asthma and IgE-mediated allergy (type I allergy), especially pollen allergy and house dust allergy. | 02-27-2014 |
Patent application number | Description | Published |
20080205761 | Radical Set Determination For HMM Based East Asian Character Recognition - Exemplary techniques are described for selecting radical sets for use in probabilistic East Asian character recognition algorithms. An exemplary technique includes applying a decomposition rule to each East Asian character of the set to generate a progressive splitting graph where the progressive splitting graph comprises radicals as nodes, formulating an optimization problem to find an optimal set of radicals to represent the set of East Asian characters using maximum likelihood and minimum description length and solving the optimization problem for the optimal set of radicals. Another exemplary technique includes selecting an optimal set of radicals by using a general function that characterizes a radical with respect to other East Asian characters and a complex function that characterizes complexity of a radical. | 08-28-2008 |
20080219556 | Radical-Based HMM Modeling for Handwritten East Asian Characters - Exemplary methods, systems, and computer-readable media for developing, training and/or using models for online handwriting recognition of characters are described. An exemplary method for building a trainable radical-based HMM for use in character recognition includes defining radical nodes, where a radical node represents a structural element of an character, and defining connection nodes, where a connection node represents a spatial relationship between two or more radicals. Such a method may include determining a number of paths in the radical-based HMM using subsequence direction histogram vector (SDHV) clustering and determining a number of states in the radical-based HMM using curvature scale space-based (CSS) corner detection. | 09-11-2008 |
20090003705 | Feature Design for HMM Based Eastern Asian Character Recognition - An exemplary method for online character recognition of East Asian characters includes acquiring time sequential, online ink data for a handwritten East Asian character, conditioning the ink data to produce conditioned ink data where the conditioned ink data includes information as to writing sequence of the handwritten East Asian character and extracting features from the conditioned ink data where the features include a tangent feature, a curvature feature, a local length feature, a connection point feature and an imaginary stroke feature. Such a method may determine neighborhoods for ink data and extract features for each neighborhood. An exemplary Hidden Markov Model based character recognition system may use various exemplary methods for training and character recognition. | 01-01-2009 |
20090003706 | Combining online and offline recognizers in a handwriting recognition system - Described is a technology by which online recognition of handwritten input data is combined with offline recognition and processing to obtain a combined recognition result. In general, the combination improves overall recognition accuracy. In one aspect, online and offline recognition is separately performed to obtain online and offline character-level recognition scores for candidates (hypotheses). A statistical analysis-based combination algorithm, an AdaBoost algorithm, and/or a neural network-based combination may determine a combination function to combine the scores to produce a result set of one or more results. Online and offline radical-level recognition may be performed. For example, a HMM recognizer may generate online radical scores used to build a radical graph, which is then rescored using the offline radical recognition scores. Paths in the rescored graph are then searched to provide the combined recognition result, e.g., corresponding to the path with the highest score. | 01-01-2009 |
20100163316 | Handwriting Recognition System Using Multiple Path Recognition Framework - Described is a multi-path handwriting recognition framework based upon stroke segmentation, symbol recognition, two-dimensional structure analysis and semantic structure analysis. Electronic pen input corresponding to handwritten input (e.g., a chemical expression) is recognized and output via a data structure, which may include multiple recognition candidates. A recognition framework performs stroke segmentation and symbol recognition on the input, and analyzes the structure of the input to output the data structure corresponding to recognition results. For chemical expressions, the structural analysis may perform a conditional sub-expression analysis for inorganic expressions, or organic bond detection, connection relationship analysis, organic atom determination and/or conditional sub-expression analysis for organic expressions. The structural analysis also performs subscript, superscript analysis and character determination. Further analysis may be performed, e.g., chemical valence analysis and/or semantic structure analysis. | 07-01-2010 |
20100205120 | PLATFORM FOR LEARNING BASED RECOGNITION RESEARCH - A method for researching and developing a recognition model in a computing environment, including gathering one or more data samples from one or more users in the computing environment into a training data set used for creating the recognition model, receiving one or more training parameters defining a feature extraction algorithm configured to analyze one or more features of the training data set, a classifier algorithm configured to associate the features to a template set, a selection of a subset of the training data set, a type of the data samples, or combinations thereof, creating the recognition model based on the training parameters, and evaluating the recognition model. | 08-12-2010 |
20110194771 | COMBINING ONLINE AND OFFLINE RECOGNIZERS IN A HANDWRITING RECOGNITION SYSTEM - Described is a technology by which online recognition of handwritten input data is combined with offline recognition and processing to obtain a combined recognition result. In general, the combination improves overall recognition accuracy. In one aspect, online and offline recognition is separately performed to obtain online and offline character-level recognition scores for candidates (hypotheses). A statistical analysis-based combination algorithm, an AdaBoost algorithm, and/or a neural network-based combination may determine a combination function to combine the scores to produce a result set of one or more results. Online and offline radical-level recognition may be performed. For example, a HMM recognizer may generate online radical scores used to build a radical graph, which is then rescored using the offline radical recognition scores. Paths in the rescored graph are then searched to provide the combined recognition result, e.g., corresponding to the path with the highest score. | 08-11-2011 |
20110229038 | Feature Design for HMM Based Eastern Asian Character Recognition - An exemplary method for online character recognition of East Asian characters includes acquiring time sequential, online ink data for a handwritten East Asian character, conditioning the ink data to produce conditioned ink data where the conditioned ink data includes information as to writing sequence of the handwritten East Asian character and extracting features from the conditioned ink data where the features include a tangent feature, a curvature feature, a local length feature, a connection point feature and an imaginary stroke feature. Such a method may determine neighborhoods for ink data and extract features for each neighborhood. An exemplary Hidden Markov Model based character recognition system may use various exemplary methods for training and character recognition. | 09-22-2011 |
20120183223 | COMBINING ONLINE AND OFFLINE RECOGNIZERS IN A HANDWRITING RECOGNITION SYSTEM - Described is a technology by which online recognition of handwritten input data is combined with offline recognition and processing to obtain a combined recognition result. In general, the combination improves overall recognition accuracy. In one aspect, online and offline recognition is separately performed to obtain online and offline character-level recognition scores for candidates (hypotheses). A statistical analysis-based combination algorithm, an AdaBoost algorithm, and/or a neural network-based combination may determine a combination function to combine the scores to produce a result set of one or more results. Online and offline radical-level recognition may be performed. For example, a HMM recognizer may generate online radical scores used to build a radical graph, which is then rescored using the offline radical recognition scores. Paths in the rescored graph are then searched to provide the combined recognition result, e.g., corresponding to the path with the highest score. | 07-19-2012 |
20120251006 | FEATURE DESIGN FOR CHARACTER RECOGNITION - An exemplary method for online character recognition of characters includes acquiring time sequential, online ink data for a handwritten character, conditioning the ink data to produce conditioned ink data where the conditioned ink data includes information as to writing sequence of the handwritten character and extracting features from the conditioned ink data where the features include a tangent feature, a curvature feature, a local length feature, a connection point feature and an imaginary stroke feature. Such a method may determine neighborhoods for ink data and extract features for each neighborhood. An exemplary character recognition system may use various exemplary methods for training and character recognition. | 10-04-2012 |
Patent application number | Description | Published |
20110222986 | FASTENER - A fastener includes a sleeve and a rod received in the sleeve. The sleeve includes a top end including at least one outer flange extending radially outward therefrom and at least one inner flange extending radially inward therefrom and a lower end including at least one spring tab. At least one spring tab comprises an outer flange at its end that extends radially outward. the sleeve is inserted into the receiving holes of the top article and the bottom article until the outer flange of the top end rests on the top plate, the rod is then pressed to move to drive at least one spring tab to deflect outwardly until the outer flange of at least one spring tab is held in contact with the bottom plate. | 09-15-2011 |
20110253518 | ELECTRONIC DEVICE HAVING BUTTON CAPABLE OF PREVENTING ACCIDENTAL DEPRESSION - An electronic device includes a housing and a button. The housing defines a through hole. The sidewall of the through hole defines a pair of positioning holes. The button includes a frame, a sliding bar assembly, an elastic conductive member, and a pressing member. The sliding bar assembly is received in the frame with two external ends respectively received in the positioning holes to cause the frame to be received in the through hole. The elastic conductive member is fixed in the housing. The pressing member hooks the frame and extends through the frame to resist the sliding bar assembly. When the pressing member is depressed, the pressing member resists the sliding bar assembly to cause the external ends to move out of the positioning holes. Further depress on the pressing member causes the frame to press the elastic conductive member to actuate the button. | 10-20-2011 |
20110261552 | METHOD FOR AFFIXING ADHESIVE FILMS AND MAIN BOARD WITH ADHESIVE FILMS APPLIED USING THE METHOD - A method for affixing adhesive films to a main board is provided. The main board includes a main body and a shield. The shield includes a first shield and a second shield. The second shield defines openings. When the second shield is attached to the main body, components of the main body are confined within the openings, respectively. The method includes: first absorbing a single adhesive film to an electrostatic absorbing film. Then, stamping the electrostatic absorbing film and the single adhesive film to form adhesive films that have substantially the same shape and arrangement as the openings. Next, aligning the electrostatic absorbing film with the first shield and affixing the adhesive films to the first shield. Then, removing the electrostatic absorbing film from the first shield. And, assembling the first shield to the second shield. | 10-27-2011 |
20110291535 | ELECTRONIC DEVICE AND SLIDE SWITCH THEREOF - An electronic device and a slide switch are disclosed. The slide switch includes a main body, a slider, a rotary plate rotatably connected to the main body, and a rotary arm. The main body includes a fixing space, a channel, and a first contact member protruding from a bottom of the fixing space. The slider is movable between a first position and a second position within the channel. The rotary plate includes a lateral surface and a second contact member protruding from the lateral surface. Two ends of the rotary arm are respectively connected to the slider and the lateral surface. When the slider is located in the first position, the first contact member spaces from the second contact member; when the slider is moved to the second position, the rotary arm rotates the rotary plate causing the first contact member to contact the second contact member. | 12-01-2011 |
Patent application number | Description | Published |
20130097149 | ENCAPSULATION OF MULTIPLICITY AND SPARSITY IN MULTIDIMENSIONAL QUERY EXECUTION SYSTEMS - Provided are techniques for processing a multidimensional query. For each multidimensional expression in the multidimensional query, the multidimensional expression is evaluated to generate a representation that includes an evaluation context, a degeneration status, and condensed value storage that does not store data that would be replicated due to degeneration, and the representation is stored. | 04-18-2013 |
20130097200 | ENCAPSULATION OF MULTIPLICITY AND SPARSITY IN MULTIDIMENSIONAL QUERY EXECUTION SYSTEMS - Provided are techniques for processing a multidimensional query. For each multidimensional expression in the multidimensional query, the multidimensional expression is evaluated to generate a representation that includes an evaluation context, a degeneration status, and condensed value storage that does not store data that would be replicated due to degeneration, and the representation is stored. | 04-18-2013 |
20140074769 | TUPLE REDUCTION FOR HIERARCHIES OF A DIMENSION - According to one embodiment of the present invention, a level of a first hierarchy and a second hierarchy of data attributes is determined where the first hierarchy and the second hierarchy share the determined level and each subordinate hierarchical level. The embodiment further removes from a set of tuples of a database operation at least one tuple that lacks corresponding data in a data source based on the tuple containing elements corresponding to non-intersecting sets of attributes at the determined level. Embodiments of the present invention include a method, system and computer program product for reducing tuple sets in substantially the same manner described above. | 03-13-2014 |
20140108330 | ENCAPSULATION OF MULTIPLICITY AND SPARSITY IN MULTIDIMENSIONAL QUERY EXECUTION SYSTEMS - Provided are techniques for processing a multidimensional query. For each multidimensional expression in the multidimensional query, the multidimensional expression is evaluated to generate a representation that includes an evaluation context, a degeneration status, and condensed value storage that does not store data that would be replicated due to degeneration, and the representation is stored. | 04-17-2014 |