Patent application number | Description | Published |
20090123459 | COMPOSITIONS AND METHOD FOR THE DIAGNOSIS, PREVENTION AND TREATMENT OF ALZHEIMER'S DISEASE - Disclosed herein are methods of diagnosing, preventing and treating Alzheimer's disease based on the use of an inhibitor for the binding of amyloid-β (Aβ) to FcγRIIb, and a method of screening the inhibitor. The inhibitor is selected from the group consisting of an FcγRIIb protein or a variant thereof, an FcγRIIb extracellular domain, an anti-FcγRIIb antibody, an FcγRIIb-specific peptide and an FcγRIIb-specific siRNA. The inhibitor reduces the toxic signaling and intracellular translocation of Aβ and the neurotoxicity, neuronal cell death and memory impairment mediated by Aβ by inhibiting the binding between Aβ and FcγRIIb. Thus, the inhibitor is useful in the diagnosis, prevention and treatment of Alzheimer's disease. | 05-14-2009 |
20120114669 | COMPOSITIONS AND METHOD FOR THE DIAGNOSIS, PREVENTION AND TREATMENT OF ALZHEIMER'S DISEASE - Disclosed herein are methods of diagnosing, preventing and treating Alzheimer's disease based on the use of an inhibitor for the binding of amyloid-β (Aβ) to FcγRIIb, and a method of screening the inhibitor. The inhibitor is selected from the group consisting of an FcγRIIb protein or a variant thereof, an FcγRIIb extracellular domain, an anti-FcγRIIb antibody, an FcγRIIb-specific peptide and an FcγRIIb-specific siRNA. The inhibitor reduces the toxic signaling and intracellular translocation of Aβ and the neurotoxicity, neuronal cell death and memory impairment mediated by Aβ by inhibiting the binding between Aβ and FcγRIIb. Thus, the inhibitor is useful in the diagnosis, prevention and treatment of Alzheimer's disease. | 05-10-2012 |
20150202204 | METHOD FOR TREATING TAU PROTEIN-MEDIATED DEGENERATIVE NEURONAL DISEASE - Provided is a therapeutic agent for a degenerative neuronal disease, and more particularly, a composition containing, as an active ingredient, an inhibitor of anaplastic lymphoma kinase (ALK) activity of expression for treating a degenerative neuronal disease caused by aggregation and phosphorylation of tau protein. | 07-23-2015 |
Patent application number | Description | Published |
20100147014 | FREEZING CRACK OR DISTORTION PROOF COOLING UTENSIL - The present invention relates to a cooling utensil, which is a proof of freezing-crack and distortion. More particularly, an internal cavity of the utensil is fully filled the water to freeze in the freezer for cooling the serving food, such as a law fish, fruit, cold noodle or beer to feel fresh and tasty. For using the cooling bowl, the cooling cavity is filled the water or coolant for freezing. The cooling bowl is using for serving food. The cooling cavity is formed between the upper part and the lower part. The lower part is used a base to support the upper part. The upper part has same shape and size of the lower part for placing over the lower part. The elastic plate having flexibility and elastically restoring force is attached to the lower part, the upper part for assembling. Further, the cooling bowl having a cooling cavity is filled the water or coolant and freeze to use serving food. The lower part has built a dual wall to form a vacuum gap between the inner wall and the outer wall for insulation, so that the outer wall has no condensed water gained. The elastic tube ( | 06-17-2010 |
20150153088 | Cooling Utensil for Anti Freezing Crack or Distortion - A cooling utensil has developed for anti freezing crack and distortion to serve a food or beverage, comprising that: first member formed dual container with opening, on outer lateral surface of outer container formed male thread, cavity between the inner and outer container filled water or coolant; inner container is for containing the served food; second member opposite the first member forms female thread on inside lateral surface for mating to the mail thread of the first member; elastic plate disposed between the first and second members for removable sealing the cooling cavity. The elastic plate has properties of flexibility, restoring capability. The cavity is fully-filled water or coolant to constantly contact with the inner surface of food containing portion, which has either one of dual cylindrical, dual square or other pitcher-shaped containers. The cooling cavity allows the coolant expanding when it freezes, so the utensil prevents from the freezing crack or distortion. | 06-04-2015 |
Patent application number | Description | Published |
20090238950 | Dispenser for liquid crystal display panel and method for controlling gap between substrate and nozzle using the same - A dispenser for a liquid crystal display panel includes a syringe having a nozzle provided at an end thereof, a body in which the syringe is mounted, a vertical driving stepping motor for moving the body in a vertical direction, a first sensor for detecting whether the nozzle of the syringe is in contact with a substrate, a second sensor for detecting a gap distance between the nozzle and the substrate, and a main unit for controlling the vertical driving stepping motor in response to an output from the second sensor to obtain a desired gap distance between the nozzle and the substrate. | 09-24-2009 |
20100006029 | Apparatus for aligning dispenser system, and dispenser alignment system - An apparatus for aligning a dispenser includes a table having a first alignment mark, an alignment plate provided along at least one side of the table, at least one syringe supplying a dispensing material to the alignment plate through a nozzle provided at one end portion thereof to form a second alignment mark, a first image camera provided along a side of the syringe and detecting an image of the second alignment mark, a second image camera detecting an image of the first alignment mark, and an alignment control unit aligning the image of the second alignment mark and a first reference position, and aligning an image of the first alignment mark and a second reference position. | 01-14-2010 |
20100144232 | DISPENSER FOR LIQUID CRYSTAL DISPLAY PANEL AND DISPENSING METHOD USING THE SAME - A dispenser for a liquid crystal display panel includes a table on which a substrate is loaded, an aligning substrate provided at least along one side of the substrate, at least one syringe having a nozzle at an end portion for supplying a material onto the substrate or onto the aligning substrate; and an image camera provided at a side of the syringe for detecting an image of the material on the substrate or on the aligning substrate. | 06-10-2010 |