Patent application number | Description | Published |
20080274193 | Retinoic Acid-Containing Antidiabetic Agent - The present invention aims to provide a novel agent for treating and/or preventing diabetes which agent can not only control a blood sugar level but also fundamentally treat a patient with type I diabetes suffering from destruction of β cells and a patient with type II diabetes suffering from dysfunction in insulin secretion. The present invention provides an agent for treating and/or preventing diabetes, the agent containing retinoic acid as an active ingredient. Retinoic acid incorporated as an active ingredient may be all-trans retinoic acid, an isomer thereof, a derivative thereof, a salt thereof or a prodrug thereof. Retinoic acid may be incorporated singly. Alternatively, composite particles of retinoic acid and an appropriate inorganic or organic substance are prepared, and the retinoic acid composite particles may be incorporated. | 11-06-2008 |
20090017123 | DERMAL REGENERATION ENHANCER - An object of the present invention is to provide a novel dermal regeneration enhancer. In accordance with the present invention, there is provided a dermal regeneration enhancer as a novel pharmaceutical use of lyotropic liquid crystal which has been utilized as a basic material for pharmaceutical preparations for external application and for cosmetics, and the dermal regeneration enhancer of the present invention achieves an excellent suppressive effect to aging of the skin, generation of spots, etc. | 01-15-2009 |
20090075860 | TRANSDERMAL ABSORPTION ENHANCER - An object of the present invention is to provide a transdermal absorption enhancer by which various active ingredients are transdermally absorbed. In accordance with a transdermal absorption enhancer of the present invention which effective ingredient is lyotropic liquid crystal which has been utilized as a basic material for pharmaceutical preparations for external application and for cosmetics, transdermal absorption of a macromolecular substance and a water-soluble substance was able to be improved. | 03-19-2009 |
20100305215 | DERMAL REGENERATION ENHANCER - An object of the present invention is to provide a novel dermal regeneration enhancer. In accordance with the present invention, there is provided a dermal regeneration enhancer as a novel pharmaceutical use of lyotropic liquid crystal which has been utilized as a basic material for pharmaceutical preparations for external application and for cosmetics, and the dermal regeneration enhancer of the present invention achieves an excellent suppressive effect to aging of the skin, generation of spots, etc. | 12-02-2010 |
20100324271 | PHAGE-DISPLAYING SINGLE-CHAIN ANTIBODY CAPABLE OF RECOGNIZING NON-REDUCED MANNOSE RESIDUE - It is an object of the present invention to provide antibodies which recognize non-reducing mannose residues. The present invention provides antibodies recognizing non-reducing mannose residues, which are obtained through screening of phage-display library of human scFvs by using, as an antigen, Man3-DPPE which is an artificial glycolipid synthesized from mannotriose and dipalmitoylphosphatidylethanolamine by reductive amination. | 12-23-2010 |
20100330014 | COMPOSITION FOR EXTERNAL APPLICATION ON SKIN, AND SKIN-WHITENING COSMETIC - An object of the present invention is to provide a composition for external application on the skin containing hydroquinone as an active ingredient, which has an excellent skin-whitening activity and reduced side effects. The composition for external application on the skin of the present invention as a means for achieving the object is characterized by containing hydroquinone or a derivative thereof compounded with a lyotropic liquid crystal. | 12-30-2010 |
20110065781 | Alpha-LIPOIC ACID NANOPARTICLES AND METHODS FOR PREPARING THEREOF - Provision of a stable α-lipoic acid. A method for producing α-lipoic acid nanoparticles, the method comprising the steps of: preparing an aqueous dispersion liquid containing α-lipoic acid and a nonionic surfactant; adding a divalent metal salt into the aqueous dispersion liquid, wherein the divalent metal salt is a divalent metal halide, a divalent metal acetate or a divalent metal gluconate; and adding an alkali metal carbonate or an alkali metal phosphate into the aqueous dispersion liquid which has been added with the divalent metal salt, thereby forming α-lipoic acid nanoparticles. | 03-17-2011 |
20110081418 | TRANSDERMAL ABSORPTION ENHANCER - An object of the present invention is to provide a transdermal absorption enhancer by which various active ingredients are transdermally absorbed. In accordance with a transdermal absorption enhancer of the present invention which effective ingredient is lyotropic liquid crystal which has been utilized as a basic material for pharmaceutical preparations for external application and for cosmetics, transdermal absorption of a macromolecular substance and a water-soluble substance was able to be improved. | 04-07-2011 |
20120196942 | NOVEL LIQUID CRYSTAL COMPOSITION - A liquid crystal composition contains liquid crystals containing one kind of or two or more kinds of silicone surfactants, a phenyl-modified silicone oil and water. The liquid crystal composition of the present invention contains 5 to 95% by weight in total of one kind of or two or more kinds of silicone surfactants, 0.1 to 90% by weight of a phenyl-modified silicone oil and 0.1 to 90% by weight of water. The liquid crystal composition of the present invention can solubilize hydrophobic compounds having poor solubility (for example, hydrocarbon oils such as squalane, fatty acids such as oleic acid and lipoic acid and ester oils such as cetyl isooctanoate) and is thus useful, for example, as toiletry materials and cosmetic materials. | 08-02-2012 |