Patent application number | Description | Published |
20120066215 | SEARCHING A DATABASE THAT STORES INFORMATION ABOUT INDIVIDUAL HABITABLE UNITS - Techniques for creating and searching a database that stores information about a plurality of individual habitable units (IHUs) are provided. An example of an IHU is a hotel room. Image data that depicts where a plurality of IHUs reside relative to each other is placed on a base image, such as a satellite/map image. The base image is associated with a mapping that maps points on the base image to spatial (e.g., geographical) coordinates. The coordinates of the IHU may be used to generate a computer-rendered view from a window of an IHU. Also, label input is received that labels each IHU reflected in the image data with certain information. Each label indicates a value of an attribute of an IHU, such as its size, price, distance from elevators, etc. A query that targets information about each IHU may be processed and results returned that are ranked based on criteria associated with the query. | 03-15-2012 |
20120066275 | CREATING A DATABASE THAT STORES INFORMATION ABOUT INDIVIDUAL HABITABLE UNITS - Techniques for creating and searching a database that stores information about a plurality of individual habitable units (IHUs) are provided. An example of an IHU is a hotel room. Image data that depicts where a plurality of IHUs reside relative to each other is placed on a base image, such as a satellite/map image. The base image is associated with a mapping that maps points on the base image to spatial (e.g., geographical) coordinates. The coordinates of the IHU may be used to generate a computer-rendered view from a window of an IHU. Also, label input is received that labels each IHU reflected in the image data with certain information. Each label indicates a value of an attribute of an IHU, such as its size, price, distance from elevators, etc. A query that targets information about each IHU may be processed and results returned that are ranked based on criteria associated with the query. | 03-15-2012 |
20140207499 | CHECK-IN TO A HOTEL ROOM ONLINE - Techniques for allowing prospective hotel guests to check-in online are provided. An online check-in service sends, to a computing device of a prospective guest, an electronic notification that indicates that the prospective user can check-in online instead of having to wait in line at the hotel. A series of pages are presented to the prospective guest, such as a page to allow the prospective guest to specify room preferences and other requests, a page to allow the prospective guest to accept an upgrade offer, a page to confirm payment, and/or a page that shows a room assignment. In this way, a guest does not have to wait in a hotel lobby to be assigned a room. Also, a hotel may be notified when a confirmed guest is approaching the hotel to allow hotel staff to make any arrangements necessary to expedite the process of getting the guest to his/her room. | 07-24-2014 |
Patent application number | Description | Published |
20130124237 | EFFICIENT INDEXING AND CACHING INFRASTRUCTURE FOR METASEARCH - Techniques are provided for a metasearch infrastructure. The metasearch infrastructure supports one or more of the following: hotel matching, backend support of user queries, frontend support for user queries, a cache layer that groups or organizes cached data in storage based on hotel location, scoring and ranking on the client side, experiments and rankers, duplicate booking prevention, blacklisting hotels, and indexing that utilizes a document-independent data structure to store index values. | 05-16-2013 |
20130124564 | METASEARCH INFRASTRUCTURE WITH INCREMENTAL UPDATES - Techniques are provided for a metasearch infrastructure. The metasearch infrastructure supports one or more of the following: hotel matching, backend support of user queries, frontend support for user queries, a cache layer that groups or organizes cached data in storage based on hotel location, scoring and ranking on the client side, experiments and rankers, duplicate booking prevention, blacklisting hotels, and indexing that utilizes a document-independent data structure to store index values. | 05-16-2013 |
Patent application number | Description | Published |
20080201103 | Robust Detection of Variability in Multiple Sets of Data - The present teachings comprise systems and methods for calibrating the background or baseline signal in a PCR or other reaction. The background signal derived from detected emissions of sample wells can be subjected to a normalized statistical metric, and be compared to a threshold or other standard to discard outlier cycles or other extraneous data. According to various embodiments, a relative standard deviation (relativeSTD) for the background component can be generated by dividing the standard deviation by the median of differences across all wells, where the difference is defined as the difference between maximum and minimum pixel values of a well. The relativeSTD as a metric is not sensitive to machine-dependent variations in absolute signal output that can be caused by different gain settings, different LED draw currents, different optical paths, or other instrumental variations. More accurate background characterization can be achieved. | 08-21-2008 |
20110096975 | SYSTEMS AND METHODS FOR IDENTIFYING MICROPARTICLES - Disclosed are systems and methods for identifying microparticles or features arranged in high density arrays. Using the techniques of the present teachings allow for effective discrimination and characterization of microparticles such as sequencing beads or features having densities of about 39×10 | 04-28-2011 |
20110105345 | Methods for the Analysis of High Resolution Melt Curve Data - The present application provides for various embodiments of methods for the analysis of high resolution melt (HRM) curve data; where statistical assay variations in melt curve data may result from system noise in an analysis system. Such system noise may arise from various sources, such as the thermal non-uniformity of a thermocycler block in a thermal cycler apparatus, a detection system, etc. Additionally, various methods for the analysis of HRM curve data may provide an identification of a sample without the need for a user inputted information. | 05-05-2011 |
20130218476 | METHODS FOR THE ANALYSIS OF HIGH RESOLUTION MELT CURVE DATA - The present application provides for various embodiments of methods for the analysis of high resolution melt (HRM) curve data; where statistical assay variations in melt curve data may result from system noise in an analysis system. Such system noise may arise from various sources, such as the thermal non-uniformity of a thermocycler block in a thermal cycler apparatus, a detection system, etc. Additionally, various methods for the analysis of HRM curve data may provide an identification of a sample without the need for a user inputted information. | 08-22-2013 |
20130316918 | MODEL-BASED RESIDUAL CORRECTION OF INTENSITIES - A method for improving color calls or base calls utilizes current and prior cycle multi-channel intensity data from a sequencing run to model residual cycle buildup. The model is applied to correct the multi-cycle channel intensity for the current cycle. The corrected multi-cycle channel intensity is used for color calls or base calls for the current cycle. | 11-28-2013 |
20130331992 | SYSTEMS AND METHODS FOR RUN-TIME SEQUENCING RUN QUALITY MONITORING - Systems and methods of providing run-time quality control and monitoring of a single or multiple sequencing runs are provided herein. In some embodiments, the run-time system includes or is in communication with a processor capable of determining various types of run-time information relating to the quality, progress, etc. of various sequencing runs. In some embodiments, the system can also be in communication with a user interface, for example, a GUI, capable of representing and communicating various types of information to a user regarding the quality of the individual or multiple runs, the functioning of the instrument, an error event, etc. Additionally, the system can capable of receiving actionable information from a user via the GUI thereby allowing the user to terminate or repeat various sequencing steps in a particular run, terminate a entire run, terminate all runs, allow a run to proceed, etc. | 12-12-2013 |
20140316716 | Methods, Systems, and Computer Readable Media for Improving Base Calling Accuracy - A method includes exposing template polynucleotide strands, sequencing primers, and polymerase to flows of nucleotide species; obtaining a series of measured intensity values and randomly selecting a training subset therefrom; generating series of base calls using a base caller and aligning the series of base calls to a reference genome or sequence using an aligner; determining intensity value thresholds and parameters of a linear transformation corresponding to different homopolymer lengths and nucleotide species; generating series of base calls corresponding to the series of measured intensity values using at least some of the parameters of a linear transformation; and recalibrating the series of base calls corresponding to the plurality of series of measured intensity values using at least some of the intensity value thresholds. | 10-23-2014 |
Patent application number | Description | Published |
20080212899 | SYSTEM AND METHOD FOR SEARCH PORTIONS OF OBJECTS IN IMAGES AND FEATURES THEREOF - Embodiments enable searching of portions of objects in images, including programmatically analyzing each image in a collection in order to determine image data that, for individual images in the collection, represents one or more visual characteristics of a portion of an object shown in that image. A user is enabled to specify one or more search criteria that includes image data, and a search result may be determined based on one or more images in the collection that show a corresponding object that has a portion that satisfies a threshold. The threshold is defined at least in part by the one or more search criteria. | 09-04-2008 |
20100135582 | SYSTEM AND METHOD FOR SEARCH PORTIONS OF OBJECTS IN IMAGES AND FEATURES THEREOF - Embodiments enable searching of portions of objects in images, including programmatically analyzing each image in a collection in order to determine image data that, for individual images in the collection, represents one or more visual characteristics of a portion of an object shown in that image. A user is enabled to specify one or more search criteria that includes image data, and a search result may be determined based on one or more images in the collection that show a corresponding object that has a portion that satisfies a threshold. The threshold is defined at least in part by the one or more search criteria. | 06-03-2010 |
20100135597 | SYSTEM AND METHOD FOR ENABLING IMAGE SEARCHING USING MANUAL ENRICHMENT, CLASSIFICATION, AND/OR SEGMENTATION - Embodiments described herein provide for a system for creating a data collection of recognized images. The system includes an image analysis module that is configured to programmatically analyze individual images in a collection of images in order to determine information about each image in the collection. The system may also include a manual interface that is configured to (i) interface with one or more human editors, and (ii) displays a plurality of panels concurrently. Individual panels may be provided for one or more analyzed images, and individual panels may be configured to display information that is at least indicative of the one or more images of that panel and/or of the information determined from the one or more images. Additionally, the manual interface enables the one or more human editors to view the plurality of panels concurrently and to interact with each of the plurality of panels in order to correct or remove any information that is incorrectly determined from the image of that panel. | 06-03-2010 |
20100166339 | SYSTEM AND METHOD FOR ENABLING IMAGE RECOGNITION AND SEARCHING OF IMAGES - Embodiments programmatically analyze each of a plurality of images in order to determine one or more visual characteristics about an item shown in each of the plurality of images. Data is stored corresponding to the one or more visual characteristics. An interface in is provided for which a user is able to specify one or more search criteria. In response to receiving the one or more search criteria, a search operation is performed to identify one or more items that have a visual characteristic that satisfies at least some of the one or more search criteria. | 07-01-2010 |
20120323738 | System and Method for Using Image Analysis and Search in E-Commerce - Embodiments described herein provide a system and method for providing merchandise items at a network site. According to an embodiment, an image of a merchandise item is obtained. The image is programmatically analyzed to determine information about the merchandise item. The information is used to generate a presentation that includes the merchandise item. | 12-20-2012 |
20130121571 | SYSTEM AND METHOD FOR SEARCH PORTIONS OF OBJECTS IN IMAGES AND FEATURES THEREOF - Embodiments enable searching of portions of objects in images, including programmatically analyzing each image in a collection in order to determine image data that, for individual images in the collection, represents one or more visual characteristics of a portion of an object shown in that image. A user is enabled to specify one or more search criteria that includes image data, and a search result may be determined based on one or more images in the collection that show a corresponding object that has a portion that satisfies a threshold. The threshold is defined at least in part by the one or more search criteria. | 05-16-2013 |
20130127893 | SYSTEM AND METHOD FOR ENABLING IMAGE SEARCHING USING MANUAL ENRICHMENT, CLASSIFICATION, AND/OR SEGMENTATION - A system includes an image analysis module that is configured to programmatically analyze individual images in a collection of images in order to determine information about each image in the collection. The system may also include a manual interface that is configured to (i) interface with one or more human editors, and (ii) displays a plurality of panels concurrently. Individual panels may be provided for one or more analyzed images, and individual panels may be configured to display information that is at least indicative of the one or more images of that panel and/or of the information determined from the one or more images. | 05-23-2013 |
Patent application number | Description | Published |
20080207190 | Systems and Methods to Confirm Initiation of a Callback - Methods and apparatuses to initiate callback with confirmation. In one embodiment, a method includes: receiving a reference (e.g., a callback phone number) in a request for a connection to a destination; providing a code via the reference in response to the request; receiving a code to confirm the request; determining whether the received code matches the provided code; and initiating a connection via the reference for the connection to the destination if the received code matches the provided code. | 08-28-2008 |
20080262910 | Methods and Systems to Connect People via Virtual Reality for Real Time Communications - Methods and systems for connecting people for real time communications via a virtual reality environment. One embodiment includes: a virtual reality server to host a virtual reality world and to present, to a customer in the virtual reality world, an advertisement including a reference assigned to the advertisement; a session border controller to interface with a packet switched network; and one or more telecommunication servers coupled to the session border controller to connect the customer to an advertiser of the advertisement for real time communications in response to a request received via the reference embedded in the advertisement and presented to the customer in the virtual reality world. In one embodiment, the advertiser is charged an advertisement fee based on connecting the customer and the advertiser for real time communications via the advertisement presented in the virtual reality world. | 10-23-2008 |
20080262911 | Methods and Systems to Search in Virtual Reality for Real Time Communications - Methods and systems to obtain information in a virtual reality environment for real time communication connections. One embodiment includes: a virtual reality server to host a virtual reality world and an avatar representing a participant of the virtual reality world, the virtual reality world including a virtual object to receive a message from an avatar; a controller to determine a context of the message and select an advertisement based on the context for presentation via the virtual object, the presented advertisement including an embedded reference to be used to request for a connection for real time communications; a session border controller to interface with a packet switched network; and one or more telecommunication servers coupled to the session border controller to connect the avatar to an advertiser of the advertisement for real time communications in response to a user of the avatar selecting the reference. | 10-23-2008 |
20080263446 | Methods and Systems to Connect People to Services via Virtual Reality - Methods and systems for connecting people to services delivered via a virtual reality environment. One embodiment includes: a virtual reality server to host a three dimensional virtual reality world; and a connection provider to interface between the virtual reality server and a customer and to interface between the virtual reality server and an advisor, the connection provider to present the advisor and to cause the virtual reality server to teleporting an avatar, representing the customer or the advisor in the virtual reality world, to a location in the virtual reality world for a meeting between the customer and the advisor, the connection provider to monitor a duration of the meeting in the virtual reality world and to charge the customer on behalf of the advisor for services delivered by the advisor during the meeting in the virtual reality world. | 10-23-2008 |
20080263458 | Methods and Systems to Facilitate Real Time Communications in Virtual Reality - Methods and systems for connecting people for real time communications via a virtual reality environment. One embodiment includes: receiving a call for a real time communication session at a virtual object presented in a virtual reality world; indicating to a plurality of residents of the virtual reality world that the virtual object is being called; and responsive to an input from one resident of the plurality of residents, connecting the call to the resident for a real time communication session. | 10-23-2008 |
20080263459 | Methods and Systems to Determine Availability for Real Time Communications via Virtual Reality - Methods and systems to determine availability of people for real time communications via a virtual reality environment. One embodiment includes: associating an avatar with an advertisement; determining a location of the avatar in a virtual reality world; and determining whether an advertiser of the advertisement is available for real time communications based at least in part on the location of the avatar in the virtual reality world. In one embodiment, the availability of the advertiser is determined for real time communications via the virtual reality world and for real time communications outside the virtual reality world based on an online presence status of the avatar, a schedule of the advertiser, and/or the location of the avatar in the virtual reality world. | 10-23-2008 |
20080263460 | Methods and Systems to Connect People for Virtual Meeting in Virtual Reality - Methods and systems for connecting people for real time communications in a virtual reality environment. One embodiment includes: a virtual reality server to host a virtual reality world; a web server to provide an advertisement to a customer, the advertisement including a reference to a meeting with an advertiser of the advertisement in the virtual reality world, a selection of the reference from the customer to cause the virtual reality server to teleport at least one avatar to a meeting location in the virtual reality world; a session border controller to interface with a packet switched network; and one or more telecommunication servers coupled to the session border controller to connect the customer to the advertiser of the advertisement for real time communications in response to the customer selecting the advertisement. In one embodiment, the advertiser of the advertisement is charged an advertisement fee per completion of the teleporting. | 10-23-2008 |
20130243177 | SYSTEMS AND METHODS TO CONFIRM INITIATION OF A CALLBACK - Methods and apparatuses to initiate callback with confirmation. In one embodiment, a method includes: receiving a reference (e.g., a callback phone number) in a request for a connection to a destination; providing a code via the reference in response to the request; receiving a code to confirm the request; determining whether the received code matches the provided code; and initiating a connection via the reference for the connection to the destination if the received code matches the provided code. | 09-19-2013 |
20140058807 | METHODS AND SYSTEMS TO FACILITATE REAL TIME COMMUNICATIONS IN VIRTUAL REALITY - Methods and systems for connecting people for real time communications via a virtual reality environment. One embodiment includes: receiving a call for a real time communication session at a virtual object presented in a virtual reality world; indicating to a plurality of residents of the virtual reality world that the virtual object is being called; and responsive to an input from one resident of the plurality of residents, connecting the call to the resident for a real time communication session. | 02-27-2014 |
Patent application number | Description | Published |
20100015093 | Methods and compositions of treating a flaviviridae family viral infection - Briefly described, embodiments of this disclosure include compounds, pharmaceutical compositions, methods of treating a host infected with a virus from the Flaviviridae family of viruses, methods of inhibiting HCV replication in a host, methods of inhibiting the binding of NS4B polypeptide to the 3′UTR of HCV negative strand RNA in a host, methods of treating liver fibrosis in a host, and the like. | 01-21-2010 |
20100028299 | Methods and compositions of treating a flaviviridae family viral infection - Briefly described, embodiments of this disclosure include compounds, pharmaceutical compositions, methods of treating a host infected with a virus from the Flaviviridae family of viruses, methods of inhibiting HCV replication in a host, methods of inhibiting the binding of NS4B polypeptide to the 3′UTR of HCV negative strand RNA in a host, methods of treating liver fibrosis in a host, and the like. | 02-04-2010 |
20100063100 | MODULATORS OF ALDEHYDE DEHYDROGENASE ACTIVITY AND METHODS OF USE THEREOF - The present invention provides compounds that function as modulators of aldehyde dehydrogenase activity; and pharmaceutical compositions comprising the compounds. The present invention provides therapeutic methods involving administering a subject compound, or a subject pharmaceutical composition. | 03-11-2010 |
20100113423 | Modulators of Aldehyde Dehydrogenase and Methods of Use Thereof - The present disclosure provides compounds that function as modulators of aldehyde dehydrogenase (ALDH) enzymatic activity, as well as compositions and formulations comprising the compounds. The present disclosure provides therapeutic methods involving administering a subject compound, or a subject pharmaceutical composition. | 05-06-2010 |
20100298342 | Spiropiperidine beta-secretase inhibitors for the treatment of Alzheimer's Disease - The present invention is directed to spiropiperidine compounds of formula (I) and tautomers thereof, which are inhibitors of the beta-secretase enzyme and that are useful in the treatment of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the treatment of such diseases in which the beta-secretase enzyme is involved. | 11-25-2010 |
20110052536 | METHODS OF TREATING A FLAVIVIRIDAE FAMILY VIRAL INFECTION AND COMPOSITIONS FOR TREATING A FLAVIVIRIDAE FAMILY VIRAL INFECTION - Briefly described, embodiments of this disclosure include compositions, pharmaceutical compositions, methods of treating a host infected with a virus from the Flaviviridae family of viruses, methods of treating HCV replication in a host, methods of inhibiting the binding of NS4B polypeptide to the 3′UTR of HCV negative strand RNA in a host, methods of treating liver fibrosis in a host, and the like. | 03-03-2011 |
20110217265 | Screening for Inhibitors of HCV Amphipathic Helix (AH) Function - Screening methods are provided for identifying pharmacologic inhibitors of HCV amphipathic helix (AH) function, which inhibitors are useful in the prevention and treatment of HCV infection. Also provided are compounds useful in the inhibition of viral replication. The methods of the invention are based on the unexpected discovery that the presence of an AH, e.g. an AH of an HCV polypeptide, causes an increase in the apparent diameter of the vesicles. The methods of the invention provide for addition of AH peptides to lipid vesicles, for example in a high-throughput format; which addition may be performed in the absence or presence of a candidate pharmacologic agent. The change in apparent vesicle size is measured, and compared to control samples. An increase in vesicle size or aggregation is indicative of AH function being present; and a lack of increase is indicative that the AH function is absent or has been inhibited by a test agent. | 09-08-2011 |
20120148534 | METHODS AND COMPOSITIONS OF TREATING A FLAVIVIRIDAE FAMILY VIRAL INFECTION - Briefly described, embodiments of this disclosure include compounds, pharmaceutical compositions, methods of treating a host infected with a virus from the Flaviviridae family of viruses, methods of inhibiting HCV replication in a host, methods of inhibiting the binding of NS4B polypeptide to the 3′UTR of HCV negative strand RNA in a host, methods of treating liver fibrosis in a host, and the like. | 06-14-2012 |
20120232062 | AZAINDAZOLES TO TREAT FLAVIVIRIDAE VIRUS INFECTION - Azaindazole compounds are useful for treating Flaviviridae virus infection, including HCV infection. | 09-13-2012 |
20120276050 | METHODS AND COMPOSITIONS OF TREATING A FLAVIVIRIDAE FAMILY VIRAL INFECTION - Clemizole and clemizole analog compounds, and pharmaceutical compositions of the same, are useful in methods of treating a host infected with a virus from the Flaviviridae family of viruses, methods of inhibiting HCV replication in a host, methods of inhibiting the binding of NS4B polypeptide to the 3′UTR of HCV negative strand RNA in a host, and methods of treating liver fibrosis in a host. | 11-01-2012 |
20130253010 | Modulators of Aldhehyde Dehydrogenase Activity and Methods of Use Thereof - The present invention provides compounds that function as modulators of aldehyde dehydrogenase activity; and pharmaceutical compositions comprising the compounds. The present invention provides therapeutic methods involving administering a subject compound, or a subject pharmaceutical composition. | 09-26-2013 |
20130267501 | Modulators of Aldehyde Dehydrogenase and Methods of Use Thereof - The present disclosure provides compounds that function as modulators of aldehyde dehydrogenase (ALDH) enzymatic activity, as well as compositions and formulations comprising the compounds. The present disclosure provides therapeutic methods involving administering a subject compound, or a subject pharmaceutical composition. | 10-10-2013 |
20140066598 | Modified Amino Acids - Provided herein are modified amino acids comprising an azido group, polypeptides, antibodies and conjugates comprising the modified amino acids, and methods of producing the polypeptides, antibodies and conjugates comprising the modified amino acids. The polypeptides, antibodies and conjugates are useful in methods of treatment and prevention, methods of detection and methods of diagnosis. | 03-06-2014 |
20140343045 | Modulators of Aldehyde Dehydrogenase and Methods of Use Thereof - The present disclosure provides compounds that function as modulators of aldehyde dehydrogenase (ALDH) enzymatic activity, as well as compositions and formulations comprising the compounds. The present disclosure provides therapeutic methods involving administering a subject compound, or a subject pharmaceutical composition. | 11-20-2014 |
20150044169 | METHODS OF TREATING A FLAVIVIRIDAE FAMILY VIRAL INFECTION, COMPOSITIONS FOR TREATING A FLAVIVIRIDAE FAMILY VIRAL INFECTION, AND SCREENING ASSAYS FOR IDENTIFYING COMPOSITIONS FOR TREATING A FLAVIVIRIDAE FAMILY VIRAL INFECTION - Briefly described, embodiments of this disclosure include compositions, pharmaceutical compositions, methods of treating a host infected with a virus from the Flaviviridae family of viruses, methods of identifying a candidate agent for the treatment of hepatitis C virus (HCV) infection, and the like. | 02-12-2015 |