Patent application number | Description | Published |
20140242154 | Compounds, Compositions, Methods, and Kits Relating to Telomere Extension - Compounds and compositions for the transient expression of exogenous telomerase activity in a cell are provided. The compounds and compositions, which relate to a ribonucleic acid coding for a telomerase reverse transcriptase, are useful in the extension of telomeres in cells needing such treatment. Such cells include, for example, cells that contain shortened telomeres and cells from subjects that may benefit from telomere extension, for example subjects that suffer from, or are at risk of suffering from, age-related or other illnesses. Also provided are methods of extending telomeres through the administration of the provided compounds and compositions to animal cells, either in vitro or in vivo, and kits including the compounds or compositions and instructions for use. | 08-28-2014 |
20140242155 | Compounds, Compositions, Methods, and Kits Relating to Telomere Extension - Compounds and compositions for the transient expression of exogenous telomerase activity in a cell are provided. The compounds and compositions, which relate to a ribonucleic acid coding for a telomerase reverse transcriptase, are useful in the extension of telomeres in cells needing such treatment. Such cells include, for example, cells that contain shortened telomeres and cells from subjects that may benefit from telomere extension, for example subjects that suffer from, or are at risk of suffering from, age-related or other illnesses. Also provided are methods of extending telomeres through the administration of the provided compounds and compositions to animal cells, either in vitro or in vivo, and kits including the compounds or compositions and instructions for use. | 08-28-2014 |
20150225699 | ACTIVATION OF INNATE IMMUNITY FOR ENHANCED NUCLEAR REPROGRAMMING OF SOMATIC CELLS WITH mRNA - The nuclear reprogramming of somatic cells with mRNA encoding reprogramming factors is shown to be greatly accelerated by activation of innate immune responses in the somatic cell. Methods of activating innate immunity include activation of PKR, of toll-like receptors, e.g. TLR3, etc. In some embodiments the mRNA provides the activator of innate immunity. | 08-13-2015 |
Patent application number | Description | Published |
20090041816 | Coated particles - A coated particle is disclosed comprising a core, a first innermost layer coating the core, a second middle layer coating the first innermost layer and a third outermost layer coating the second middle layer, wherein the core comprises at least a water-in-oil emulsion or a fat and/or oil, wherein the first innermost layer comprises at least one emulsifier and, wherein the second middle layer comprises either one or more polyanions or one or more polycations and the third outermost layer comprises one or more polyelectrolytes only of opposing charge to that of the polyanions or polycations of the second middle layer. The inventors have observed that the particle has improved stability, particularly when the particles are small as the forces between said small particles to aggregate is greater and simultaneously provides a delivery vehicle for included actives and/or flavours. A method for the manufacture of the particle is also disclosed as is a product selected from the group consisting of a food product, a home care product, a personal care product and a pharmaceutical product, wherein each product comprises a plurality of the coated particles. | 02-12-2009 |
20100197810 | OIL-IN-WATER EMULSIONS - Improved oil-in-water emulsions are provided and a method for their manufacture. In particular, the emulsions comprise a means to control delivery of oil-soluble or water-soluble actives in a core comprising a liquid oil or gel oil continuous phase, which actives can be delivered with improved deposition to surfaces such as, in particular, the skin, gastro-intestinal tract and that defined by the oral cavity. The emulsions are also noted for their improved stability. | 08-05-2010 |
Patent application number | Description | Published |
20150061190 | Large Shells Manufacturing Apparatus - The current document discloses an apparatus and method that support manufacture of large 3D hollow objects or shells with thin walls including curved surfaces with high and low curvature change ratio and alleviate or significantly reduce the need for support structures. Further to this, introduction of support structures becomes a function of the curved surface curvature change ratio. | 03-05-2015 |
20150217516 | Large Shells Manufacturing Apparatus - The current document discloses an apparatus and method that support manufacture of large 3D hollow objects or shells with thin walls including curved surfaces with high and low curvature change ratio and alleviate or significantly reduce the need for support structures. Further to this, introduction of support structures becomes a function of the curved surface curvature change ratio. | 08-06-2015 |
20150231827 | Additive Manufacturing Device - An additive manufacturing device is disclosed that enables the manufacturing of 3D objects at a short time. The device uses multiple writing heads to write simultaneously different segments of the object and thus complete the object manufacture in a shorter time as compared to a one head additive manufacturing device. | 08-20-2015 |
20150314534 | Large Shells Manufacturing Apparatus - The current document discloses an apparatus and method that support manufacture of large 3D hollow objects or shells with thin walls including curved surfaces with high and low curvature change ratio and alleviate or significantly reduce the need for support structures. Further to this, introduction of support structures becomes a function of the curved surface curvature change ratio. | 11-05-2015 |