Wolter, US
Bob Wolter, Rancho Santa Fe, CA US
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20120226976 | SCROLL-BASED SERIALIZED BOOK READER - A method and a device are disclosed for a reader application configured to run on a computing device. The scrolling reader application, when run on the computing device, causes the computing device to display a scrolling text stream field, a control panel configured to control the scrolling of the text stream, a status line including at least a page number and a line number, and several special-function elements including a table of content button, a current position button, and an index button. The scrolling reader application may further include a module to serialize a text document into a character array usable to form a text stream. | 09-06-2012 |
20150058721 | SCROLL-BASED SERIALIZED BOOK READER - A method and a device are disclosed for a reader application configured to run on a computing device. The scrolling reader application, when run on the computing device, causes the computing device to display a scrolling text stream field, a control panel configured to control the scrolling of the text stream, a status line including at least a page number and a line number, and several special-function elements including a table of content button, a current position button, and an index button. The scrolling reader application may further include a module to serialize a text document into a character array usable to form a text stream. | 02-26-2015 |
Brian W. Wolter, New York, NY US
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20150178746 | SYSTEM AND METHOD FOR NEAR REAL-TIME, UNSOLICITED, UNBIASED DEMAND COLLECTION FOR DISTRIBUTING CONSUMER ITEMS - This invention is a system for determining non-abstract consumer demand for an item comprising: a user agent, an aggregator and a sales agent for transmitting the quantity price demand information to a supplier computer system, receiving an initial price and quantity of the discrete item being offered by the supplier from the supplier computer system, setting the current price to the initial price, (a) transmitting the discrete item information to remote computer systems that represent the user's desire for the discrete item, (b) waiting an predetermined period of time, (c) reducing the quantity of items available by the number sold during the predetermined period of time, (d) reducing the current price and performing steps (a), (b), (c) and (d) until: (i) the quantity of items available is reduced to zero or (ii) a sale termination period is reached or (iii) a maximum price reduction has been reached. | 06-25-2015 |
Brian William Wolter, New York, NY US
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20150178395 | SYSTEM AND METHOD FOR IDEMPOTENT INTERACTIVE DISPARATE OBJECT DISCOVERY, RETRIEVAL AND DISPLAY - The present invention is a system that performs a real time on-demand searching for items such as goods or services with specific search criteria, and returns a set of search results that are deduped and can be updated when modifications to the search results occur. The functionality is provided by a idempotence search system having a user agent that asynchronously receives search results from user's remote computing devices, a set of fetchers for retrieving search results from associated external site and organizing the results in a results queue, a plurality of parser operating in parallel, a broadcaster wherein the user agent includes retrieving the difference from the delta queue, retrieving the results associated with the difference and displaying the results for the user. | 06-25-2015 |
20150178807 | SYSTEM AND METHOD FOR ASYNCHRONOUS CONSUMER ITEM SEARCHING REQUESTS WITH SYNCHRONOUS PARALLEL SEARCHING - This invention is a system for providing persistence searching for consumer items that performs the steps of: retrieving a set of get requests uniquely associated with external vendor sites wherein each get request is specifically formatted for its external vendor site and simultaneously transmitting the set of get requests to the respective external vendor sites. Asynchronously receiving current results from the external vendor sites, extracting the price from the current results for each item contained in the current results received from the external vendor sites, comparing the extracted price of the current results with the price of a previously stored results, generating a notification and including in the notification, a link to the external vendor site to provide a purchasing opportunity to a user where the price of the current results is lower than the price of the stored results. | 06-25-2015 |
Brian Williams Wolter, New York, NY US
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20150178747 | SYSTEM AND METHOD FOR DETERMINING AND DISTRIBUTING CONSUMER ITEMS ACCORDING TO DYNAMIC DEMAND LEVELS - This invention is directed to a computerized system for asynchronously receiving persistent query requests, selecting a subset from the plurality of persistent query requests for a particular item, ordering the subset of persistent query requests into a plurality of equal range brackets between the highest desired price to the lowest desired price, receiving a set of sales program criteria from the vendor computer system created in response to the vendor computer system previously receiving the subset of persistent query requests having available quantity and available price information for the items available for sale from the vendor, determining the number of available items from the sales program criteria having available prices that are within a first desired range bracket, and transmitting a notification to the remote computer devices associated with the query results having available prices in the first range bracket. | 06-25-2015 |
Douglas M. Wolter, Cumming, GA US
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20090255104 | Simplified generator removal operation for rotor removal of center generator in a single shaft combined cycle machine - A method of removing a rotor from a generator of a single shaft combined cycle machine comprising a gas turbine, generator and steam turbine axially aligned, the method comprising: disengaging fasteners securing stator support feet of the generator to a foundation thereof; vertically raising the generator above the foundation; disposing temporary supports on each lateral side of the generator, beneath the stator support feet; securing the stator support feet to the temporary support columns; installing a maintenance personnel access platform over the steam turbine, axially adjacent the generator; and removing the rotor from the generator to the access platform. | 10-15-2009 |
Gerry Wolter, Cincinnati, OH US
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20110220210 | Hydronic Space and Water Heater - A compact hydronic space and water heating apparatus and system is disclosed for use in a recreational vehicle. A liquid heating medium, stored within a low pressure tank, is recirculated through a gas fired heater thereby maintaining a desired set point temperature. The liquid heating medium is further circulated through the vehicles hydronic space heaters to heat the interior of the vehicle. Further fresh domestic water is passed through a heat transfer coil within the tank whereby hot domestic water may be provided. An auxiliary heating device is attached to the tank whereby hot combustion engine coolant may assist in maintaining the temperature of the liquid heating medium within the tank and/or reversed to pre heat the combustion engine if and when needed. | 09-15-2011 |
Gerry C. Wolter, Cincinnati, OH US
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20120060951 | GAS MODULATION AND TEMPERATURE CONTROL VALVE - An apparatus comprises a body, a first poppet, and a second poppet. The body comprises a first fluid channel and a second fluid channel. The first fluid channel and the second fluid channel are operable to be fluidly isolated from each other. The first poppet is positioned in the first fluid channel, and the first poppet is operable to be moveable within the first fluid channel. The second poppet is positioned within the second fluid channel, and the second poppet is operable to be moveable within the second fluid channel. The first poppet and the second poppet are operable to be mechanically coupled together such that movement of the first poppet within the first channel is operable to cause sympathetic movement of the second poppet within the second fluid channel. | 03-15-2012 |
James Wolter, Spring Lake, MI US
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20140069483 | SINGLE AND MULTI-AXIAL ARTICULATED BALLASTED PHOTOVOLTAIC MOUNT - A solar panel mount system includes a ballasted block support resting on a ground surface, a post pivoted to the block support at a lower pivot, and a solar panel frame pivoted to the post at an upper pivot with a center of gravity over the ballasted block support and facing a desired sunlight-receiving direction. The upper pivot is selected to be at a desired adjusted height. The frame includes a yoke supported at the upper pivot and support beams supporting a solar panel. A method of installation includes placing the ballasted block support on the ground, and attaching the remaining components at desired angles to locate a center of gravity of the solar panel frame over the ballasted block support, and fixing an angle of the solar panel frame at a desired sun-facing position. A related method includes interconnecting solar panel frames on posts in a generally straight row. | 03-13-2014 |
20160020728 | DISTRIBUTED ENERGY STORAGE AND POWER QUALITY CONTROL IN PHOTOVOLTAIC ARRAYS - A solar electric system comprises photovoltaic elements having integrated energy storage and control, ideally on each PV-panel. The energy storage media may be primary or secondary cylindrical cells interconnected into a battery and/or an array of capacitors (or super-capacitors) and are accompanied by an electronic control circuit which may perform a variety of functions, including but not limited to power quality control, load following, pulse powering, active line transient suppression, local sensing, remote reporting, wireless or wired communications allowing two way programmable control through local or remote operation. The operation of the system may yield direct current or with the integration of bidirectional micro-inverters create distributed alternating current generation enhanced with energy storage and control two way energy flows between the solar system and the grid. | 01-21-2016 |
James F. Wolter, Spring Lake, MI US
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20110303262 | SOLAR PANEL SYSTEM WITH MONOCOQUE SUPPORTING STRUCTURE - A solar panel system comprises a monocoque forming an enlarged solar-facing generally-convex outer support surface when in an installed position and that supports solar cells at optimal angles for capturing solar energy. The monocoque provides a stressed-skin support reducing weight while maintaining strength, optimal support surface, and minimizing cost. A post engages and supports adjacent edges of a pair of adjacent monocoques. An electrical circuit connects the solar cells for electrical flow and power management, and preferably includes a controller for controlling power from the solar cells, including combining them in series or parallel as optimal for a given systems configuration. The illustrated monocoque includes a roll formed sheet or a number of sheets, stacked vertically together and anchored to spaced posts using connectors in a “fence-like” pattern. | 12-15-2011 |
20140103855 | DISTRIBUTED ENERGY STORAGE AND POWER QUALITY CONTROL IN PHOTOVOLTAIC ARRAYS - A solar electric system comprises photovoltaic elements having integrated energy storage and control, ideally on each PV-panel. The energy storage media may be primary or secondary cylindrical cells interconnected into a battery and/or an array of capacitors (or super-capacitors) and are accompanied by an electronic control circuit which may perform a variety of functions, including but not limited to: power quality control, load following, pulse powering, active line transient suppression, local sensing, remote reporting, wireless or wired communications allowing two way programmable control through local or remote operation. The operation of the system may yield direct current or with the integration of bidirectional micro-inverters create distributed alternating current generation enhanced with energy storage and control two way energy flows between the solar system and the grid. | 04-17-2014 |
20160099673 | SOLAR PANEL SYSTEM WITH MONOCOQUE SUPPORTING STRUCTURE - A solar panel system comprises a monocoque forming an enlarged self-supporting solar-facing generally-convex support surface when in an installed position supports solar cells attached (or formed directly on it) at optimal angles for capturing solar energy. The monocoque provides a stressed-skin or stiff-sheet support reducing weight while maintaining strength and minimizing cost. A post engages and supports adjacent edges of a pair of adjacent monocoques. An electrical circuit connects the solar cells for electrical flow and power management, and preferably includes a controller for controlling power from the solar cells, including combining them in series or parallel as optimal for a given systems configuration. The illustrated monocoque includes a roll formed sheet or a number of sheets, stacked vertically together and anchored to spaced posts using connectors in a “fence-like” pattern. | 04-07-2016 |
James Frederick Wolter, Spring Lake, MI US
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20130082529 | POWER GENERATION SYSTEM WITH INTEGRATED RENEWABLE ENERGY GENERATION, ENERGY STORAGE, AND POWER CONTROL - A power generation system comprises a conventional motor-generator system as may be found in a stand-by power system with the addition of integrated renewable and stored energy assets. A software defined control system allows for optimizing total cost of power and allows user control or interconnection with micro-grid or Utility Power systems. | 04-04-2013 |
20150008864 | DISTRIBUTED ENERGY STORAGE AND POWER QUALITY CONTROL IN PHOTOVOLTAIC ARRAYS - A solar electric system comprises photovoltaic elements having integrated energy storage and control, ideally on each PV-panel. The energy storage media may be primary or secondary cylindrical cells interconnected into a battery and/or an array of capacitors (or super-capacitors) and are accompanied by an electronic control circuit which may perform a variety of functions, including but not limited to power quality control, load following, pulse powering, active line transient suppression, local sensing, remote reporting, wireless or wired communications allowing two way programmable control through local or remote operation. The operation of the system may yield direct current or with the integration of bidirectional micro-inverters create distributed alternating current generation enhanced with energy storage and control two way energy flows between the solar system and the grid. | 01-08-2015 |
20150318699 | POWER GENERATION SYSTEM WITH INTEGRATED RENEWABLE ENERGY GENERATION, ENERGY STORAGE, AND POWER CONTROL - A power generation system comprises a conventional motor-generator system as may be found in a stand-by power system with the addition of integrated renewable and stored energy assets. A software defined control system allows for optimizing total cost of power and allows user control or interconnection with micro-grid or Utility Power systems. | 11-05-2015 |
Jason A. Wolter, San Diego, CA US
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20120066095 | Method and Apparatus for Purchasing Gold and Other Precious Metals - A system and method for a buyer to purchase gold and gold bearing items from remote sellers. The system employs purchasers working with said buyer to seek gold bearing items from sellers. The sellers are provided with the price payable for their gold bearing item, before tendering it to the purchaser and are also afforded the ability to check gold prices before agreeing to a sale. | 03-15-2012 |
John D. Wolter, Cleveland, OH US
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20160122005 | EMBEDDED ENGINES IN HYBRID BLENDED WING BODY - A hybrid wing aircraft has an engine embedded into a body of the hybrid wing aircraft. The embedded engine has a fan that is received within a nacelle. The body of the aircraft provides a boundary layer over a circumferential portion of a fan. A system delivers additional air to correct fan stability issues raised by the boundary layer. | 05-05-2016 |
Klaus Wolter, Dexter, MI US
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20080259428 | Optical Delay - An optical delay line device includes a rotatable wheel and one or more prisms mounted about the circumference of the wheel. The one are more prisms are positioned to retroreflect the optical beam that passes approximately tangent to the wheel to cause a delay or phase shift to the beam as the wheel rotates. | 10-23-2008 |
Madelyn R. Wolter, Hartford, WI US
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20150309185 | EXTREMITY RADIATION MONITORING SYSTEMS AND RELATED METHODS - Systems and methods of monitoring radiation include a radiation monitoring glove. The glove is to be worn by a person that may be exposed to the radiation and includes at least one fiber sleeve attached to at least one finger of the glove. The glove also includes at least one scintillating fiber disposed in the at least one fiber sleeve. The scintillating fiber is configured for generating photons responsive to exposure to radiation in proximity thereto. The glove also includes a photon-sensing device disposed in a collector pocket on the glove. The photon-sensing device is operably coupled to a distal end of the one or more scintillating fibers. | 10-29-2015 |
Nick Wolter, Greenville, WI US
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20140115844 | TAMPON METHOD OF MANUFACTURE - A method of manufacturing a tampon comprises the steps of at least partially overlaying a web of base material with a web of absorbent material. The web of absorbent material is secured to the web of base material with a first securement. At least one of the web of base material and the web of absorbent material is folded after the first securement. The web of absorbent material is further secured to the web of base material with a second securement that is a stronger securement than the first securement. The web of absorbent material and the web of base material together define a web of cover material. The web of cover material is applied to an absorbent structure. The web of cover material and the absorbent structure is manipulated such that the web of cover material extends about a circumference of the absorbent structure to form a tampon. | 05-01-2014 |
20140115845 | METHOD OF MANUFACTURING TAMPONS - A method of manufacturing a tampon includes transporting a web of material in a machine direction. The web of material has a base web and an absorbent web. The absorbent web has a free end and a bonded end wherein the bonded end is bonded to the base web. At least the free end of the absorbent web of the web to is controlled to inhibit movement of the absorbent web relative to the base web. The web of material is cut into discrete web segments while controlling at least the free end of the absorbent web. The discrete web segments is bonded to a substrate. | 05-01-2014 |
20140115846 | METHOD OF MANUFACTURING TAMPONS WITH CONTACT ELEMENTS - A method of manufacturing a tampon includes transporting a web of material in a machine direction. The web of material has a base web and an absorbent web. The absorbent web has a free end and a bonded end wherein the bonded end is bonded to the base web. The free end of the absorbent web is moved in spaced relationship with the base web. The base web is bonded to a substrate. | 05-01-2014 |
20140115847 | METHOD OF MANUFACTURING TAMPONS BY FORMING A SOFTWIND WITH CONTACT ELEMENTS - A method of manufacturing a tampon generally comprises forming a softwind including a core and a cover overlying and at least in part covering the core. The cover carries an absorbent web having a free end and a bonded end wherein the free end is capable of moving relative to the cover. The softwind is passed through a transfer assist device to facilitate the transferring of the free end of the absorbent web without the absorbent web becoming misaligned relative to the cover. | 05-01-2014 |
Roger Lynn Wolter, Kirkland, WA US
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20140372764 | SCHEMA SIGNING - In one embodiment, an object in a database schema may be verified as having a valid digital signature associated with a trusted entity. An application may be permitted access to the object of the database schema only when the object of the database schema is verified to have a valid digital signature associated with the trusted entity. In another embodiment, an object in a database schema may be verified as having a digital signature associated with at least one trusted entity. An application may be permitted access to the object of the database schema only when the digital signature for the object is verified to be associated with the at least one trusted entity. | 12-18-2014 |
Scott Wolter, Hillsborough, NC US
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20120122736 | SENSORS INCORPORATING ANTIBODIES AND METHODS OF MAKING AND USING THE SAME - A sensor comprising an electronic circuit electrically coupled to a type III-V semiconductor material, for example indium arsenide (InAs) and an antibody contacting the type III-V semiconductor material. The sensor produces measurable N changes in the electrical properties of the semiconductor upon antibody-antigen binding events. Electrical properties measurable by the electronic device may include resistivity, capacitance, impedance, and inductance. A method of detecting an antigen using sensors of the invention. A method of detecting a reaction of an analyte to a stimulus using sensors of the invention. Sensor arrays comprising multiple sensors of the invention. | 05-17-2012 |
Scott D. Wolter, Durham, NC US
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20080203431 | GaN-BASED NITRIC OXIDE SENSORS AND METHODS OF MAKING AND USING THE SAME - GaN-based heterojunction field effect transistor (HFET) sensors are provided with engineered, functional surfaces that act as pseudo-gates, modifying the drain current upon analyte capture. In some embodiments, devices for sensing nitric oxide (NO) species in a NO-containing fluid are provided which comprise a semiconductor structure that includes a pair of separated GaN layers and an AlGaN layer interposed between and in contact with the GaN layers. Source and drain contact regions are formed on one of the GaN layers, and an exposed GaN gate region is formed between the source and drain contact regions for contact with the NO-containing fluid. The semiconductor structure most preferably is formed on a suitable substrate (e.g., SiC). An insulating layer may be provided so as to cover the semiconductor structure. The insulating layer will have a window formed therein so as to maintain exposure of the GaN gate region and thereby allow the gate region to contact the NO-containing fluid. Electrical contact pads are preferably provided in some embodiments so as to be in electrical contact with the source and drain contact regions, respectively. Electrical leads may thus be connected to the contact pads. According to other embodiments, the NO detection device will include a metalloporphyrin adsorbed on the GaN gate region. | 08-28-2008 |
20110097837 | GaN-BASED NITRIC OXIDE SENSORS AND METHODS OF MAKING AND USING THE SAME - GaN-based heterojunction field effect transistor (HFET) sensors are provided with engineered, functional surfaces that act as pseudo-gates, modifying the drain current upon analyte capture. In some embodiments, devices for sensing nitric oxide (NO) species in a NO-containing fluid are provided which comprise a semiconductor structure that includes a pair of separated GaN layers and an AlGaN layer interposed between and in contact with the GaN layers. Source and drain contact regions are formed on one of the GaN layers, and an exposed GaN gate region is formed between the source and drain contact regions for contact with the NO-containing fluid. The semiconductor structure most preferably is formed on a suitable substrate (e.g., SiC). An insulating layer may be provided so as to cover the semiconductor structure. The insulating layer will have a window formed therein so as to maintain exposure of the GaN gate region and thereby allow the gate region to contact the NO-containing fluid. Electrical contact pads are preferably provided in some embodiments so as to be in electrical contact with the source and drain contact regions, respectively. Electrical leads may thus be connected to the contact pads. According to other embodiments, the NO detection device will include a metalloporphyrin adsorbed on the GaN gate region. | 04-28-2011 |
20110199102 | CHEMICAL SENSORS AND METHODS FOR MAKING AND USING THE SAME - A van der Pauw (VDP) sensor comprising an electronic circuit electrically coupled to a surface, the surface comprising a type III-V material, and the electronic circuit measuring a sheet resistivity of the surface using a VDP technique. The VDP sensor may further comprise a macromolecule, such as a porphyrin, an oligonucleotide, a protein, a polymer or a combination thereof in contact with the surface. The VDP sensors may be arranged in an array of similar or different sensors. An electronic circuit electrically coupled to a type III-V material having a two-dimensional electron gas, such as InAs or InN, the electronic circuit measuring an electrical property of the type III-V material having a two-dimensional electron gas. | 08-18-2011 |
Travis Wolter, Denver, CO US
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20140330032 | MICROBIAL PRODUCTION OF CHEMICAL PRODUCTS AND RELATED COMPOSITIONS, METHODS AND SYSTEMS - Metabolically engineered microorganism strains are disclosed, such as bacterial strains, in which there is an increased utilization of malonyl-CoA for production of a chemical product. Such chemical products include polyketides, 3-hydroxypropionic acid, and various other chemical products described herein. Methods of production also may be applied to further downstream products, such as consumer products. In various embodiments, modifications to a microorganism and/or culture system divert, at least transiently, usage of malonyl-coA from the fatty acid biosynthesis pathway and thereby provides for usage of the malonyl-coA for a chemical product other than a fatty acid. In various embodiments, the fatty acid biosynthesis pathway is modulated to produce specific fatty acids or combinations of fatty acids. | 11-06-2014 |
Travis Robert Wolter, Denver, CO US
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20150056669 | ACETYL-COA CARBOXYLASES - The present invention provides various combinations of genetic modifications to a transformed host cell that provide increase conversion of carbon to a chemical product. The present invention also provides methods of fermentation and methods of making various chemical products. | 02-26-2015 |
20150057465 | CONTROL OF GROWTH-INDUCTION-PRODUCTION PHASES - The present invention provides various combinations of genetic modifications to a transformed host cell that provide increase conversion of carbon to a chemical product. The present invention also provides methods of fermentation and methods of making various chemical products. | 02-26-2015 |
20150064754 | BIOPRODUCTION OF CHEMICALS - The present invention provides various combinations of genetic modifications to a transformed host cell that provide increase conversion of carbon to a chemical product. The present invention also provides methods of fermentation and methods of making various chemical products. | 03-05-2015 |
20150119601 | MONOFUNCTIONAL MCR + 3-HP DEHYDROGENASE - The present invention provides various combinations of genetic modifications to a transformed host cell that provide increase conversion of carbon to a chemical product. The present invention also provides methods of fermentation and methods of making various chemical products. | 04-30-2015 |
William R. Wolter, South Bend, IN US
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20080260800 | EXTRACELLULAR MATRIX CANCER VACCINE ADJUVANT - Compositions suitable for use as adjuvants in the preparation of vaccines, particularly those vaccines useful in the treatment of cancer, are provided. Methods for inhibiting tumor growth in an animal are also disclosed. Methods for immunizing an animal against cancer, such as prostate cancer, are also described. The adjuvants described are comprised of an extracellular matrix material, such as small intestinal submucosal (SIS) tissue. The preparations may take the form of sheets, gels, liquids (injectable), trocar, or other solid or semi-solid preparation. The invention provides for enhanced tumor inhibition of 2-fold or greater, compared to vaccine preparations without the extracellular matrix material, or from 4- to 5-fold, compared to preparations without the adjuvant promoting extracellular materials. | 10-23-2008 |
20090220461 | Metastasis inhibition preparations and methods - Disclosed are compositions and pharmaceutical preparations suitable for inhibiting metastasis of a malignant cancer in an animal. Methods for inhibiting and/or eliminating metastasis in an animal are also provided. In some embodiments, the preparations and compositions comprise a whole cell tumor preparation comprising tumor tissue cells and tumor connective tissue stroma. The disclosure also provides methods for preparing the preparations and pharmaceutical preparations. Inhibition of metastasis of malignant prostate cancer to the lung is shown in vivo. | 09-03-2009 |
20100233214 | Extracellular matrix cancer vaccine adjuvant - Compositions suitable for use as adjuvants in the preparation of vaccines, particularly those vaccines useful in the treatment of cancer, are provided. Methods for inhibiting tumor growth in an animal are also disclosed. Methods for immunizing an animal against cancer, such as prostate cancer, are also described. The adjuvants described are comprised of an extracellular matrix material, such as small intestinal submucosal (SIS) tissue. The preparations may take the form of sheets, gels, liquids (injectable), trocar, or other solid or semi-solid preparation. The invention provides for enhanced tumor inhibition of 2-fold or greater, compared to vaccine preparations without the extracellular matrix material, or from 4- to 5-fold, compared to preparations without the adjuvant promoting extracellular materials. | 09-16-2010 |
William R. Wolter, Granger, IN US
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20100136050 | Extracellular Matrix Materials as Vaccine Adjuvants for Diseases Associated with Infectious Pathogens or Toxins - Disclosed are vaccines and vaccine adjuvants useful in the treatment and/or prevention of infection and diseases associated with infectious pathogens, such as tetanus, as well as diseases associated with biological toxins. Also provided are methods of preparing an adjuvant and the vaccine containing the adjuvant. Methods are also provided for vaccinating/immunizing an animal against infection and diseases associated with infectious pathogens, such as tetanus, and other diseases associated with biological toxins. Adjuvant materials are presented that are prepared from an extracellular matrix material. The adjuvants are demonstrated to enhance the immunogenicity of an infectious pathogen antigen or biological toxin antigen of interest, as well as to enhance the survival of an immunized animal. | 06-03-2010 |
20110076305 | EXTRACELLULAR MATRIX MATERIALS AS VACCINE ADJUVANTS FOR DISEASES ASSOCIATED WITH INFECTIOUS PATHOGENS OR TOXINS - Disclosed are vaccines and vaccine adjuvants useful in the treatment and/or prevention of infection and diseases associated with infectious pathogens, such as tetanus, as well as diseases associated with biological toxins. Also provided are methods of preparing an adjuvant and the vaccine containing the adjuvant. Methods are also provided for vaccinating/immunizing an animal against infection and diseases associated with infectious pathogens, such as tetanus, and other diseases associated with biological toxins. Adjuvant materials are presented that are prepared from an extracellular matrix material. The adjuvant may also be described as a heterologous acellular collagenous tissue preparation. The adjuvants are demonstrated to enhance the immunogencity of an infectious pathogen antigen or biological toxin antigen of interest, as well as to enhance the survival of an immunized animal. | 03-31-2011 |