Wollacott
Andrew Wollacott, Cambridge, MA US
Patent application number | Description | Published |
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20090191607 | SYNTHETIC ENZYMES DERIVED FROM COMPUTATIONAL DESIGN - Disclosed herein are techniques for computationally designing enzymes. These techniques can be used to design variations of naturally occurring enzymes, as well as new enzymes having no natural counterparts. The techniques are based on first identifying functional reactive sites required to promote the desired reaction. Then, hashing algorithms are used to identify potential protein backbone structures (i.e., scaffolds) capable of supporting the required functional sites. These techniques were used to design 32 different protein sequences that exhibited aldol reaction catalytic function, 31 of which are defined in the Sequence Listing. Details of these 31 different synthetic aldolases are provided, including descriptions of how such synthetic aldolases can be differentiated from naturally occurring aldolases. | 07-30-2009 |
20120142077 | SYNTHETIC ENZYMES DERIVED FROM COMPUTATIONAL DESIGN - Disclosed herein are techniques for computationally designing enzymes. These techniques can be used to design variations of naturally occurring enzymes, as well as new enzymes having no natural counterparts. The techniques are based on first identifying functional reactive sites required to promote the desired reaction. Then, hashing algorithms are used to identify potential protein backbone structures (i.e., scaffolds) capable of supporting the required functional sites. These techniques were used to design 32 different protein sequences that exhibited aldol reaction catalytic function, 31 of which are defined in the Sequence Listing. Details of these 31 different synthetic aldolases are provided, including descriptions of how such synthetic aldolases can be differentiated from naturally occurring aldolases. | 06-07-2012 |
Martin Wollacott, Redditch GB
Patent application number | Description | Published |
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20130328328 | COMPRESSION LATCH - A compression latch for a closure comprising a latch mount having an inboard side and an outboard side and a latch member having a first end and a second end; and a drive shaft configured to drive the compression latch. The shaft is actuated remotely. The drive shaft is pivotably connected to the mount at a first link pivot point, the first link pivot point having a first longitudinal axis. The latch member first end is pivotably connected to the mount at a latch member pivot point remote from the first link pivot point and inboard thereof, the latch member pivot point having a second longitudinal axis substantially parallel to the first longitudinal axis. The latch member is pivotable about the latch member pivot point between an open position and a closed position. The latch member is connected to the drive shaft by a linkage such that the latch member is moveable between said open position and said closed position by rotation of the drive shaft. The latch member comprises a striker at its second end. | 12-12-2013 |
20130328331 | COMPRESSION LATCH - A compression latch comprising a housing, a handle, and a latch member is provided. The housing has an inboard and an outboard side, and defines a plane substantially parallel to a closure plane. The handle is pivotably connected to the housing at a handle pivot point having a longitudinal axis substantially parallel to said plane, and the latch member is pivotably connected to the housing through a latch member pivot point, which is remote and inboard from the handle pivot point and also has a longitudinal axis substantially parallel to that of the handle pivot point. The latch member is pivotable about the latch member pivot point between an open and a closed position. The handle is connected to the latch member by a first linkage so the latch member is moveable between said open and closed positions by angular movement of the handle about the handle pivot point. | 12-12-2013 |
Martin Wollacott, Worcestershire GB
Patent application number | Description | Published |
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20140306467 | Retention Arrangement - A retention arrangement for releasably securing a closure against a fixed body is provided. The retention arrangement includes a housing defining a mouth configured to receive a striker and defining a longitudinal axis, and at least one retention element configured to selectively retain said striker within the mouth, and movable between an open position and a closed position. The retention element is resiliently biased towards the closed position. The retention element is configured to open upon displacement due to said striker along the longitudinal axis in a first direction, and to close upon complete insertion of said striker within the mouth. The retention element is configured for rotation about at least two non-parallel axes so as to direct said striker towards the mouth. | 10-16-2014 |
20140333074 | Compression Latch - A compression latch for a closure, the latch including a housing, a latch member and an input shaft configured to drive the latch. The latch member is pivotably connected to the housing at a latch member pivot point. The latch member includes a latch arm and a striker. The latch arm first end is connected to the input shaft at the latch member pivot point, such that the latch member is pivotable about the latch member pivot point between an open position and a closed position upon operation of the input shaft. The striker is pivotably connected to the latch arm second end at a first striker pivot point. The latch arm is configured to move the striker with respect to the housing in a first arc and the linkage is configured to pivot the striker with respect to the housing about the latch arm in a second arc. | 11-13-2014 |