Patent application number | Description | Published |
20100160371 | INHIBITION OF P38 KINASE ACTIVITY BY ARYL UREAS - This invention relates to the use of a group of aryl ureas in treating cytokine mediated diseases other than cancer and proteolytic enzyme mediated diseases other than cancer, and pharmaceutical compositions for use in such therapy. | 06-24-2010 |
20110190281 | SULFONE SUBSTITUTED 2,3-DIHYDROIMIDAZO [1,2-C] QUINAZOLINE DERIVATIVES USEFUL FOR TREATING HYPER-PROLIFERATIVE DISORDERS AND DISEASES WITH ANGIOGENESIS - This invention relates to novel sulfone 2I3-dihydroimidazo[1,2-c]quinazoline compounds, pharmaceutical compositions containing such compounds and the use of those compounds or compositions for phosphotidylinositol-3-kinase (PI3K) inhibition and treating diseases associated with phosphotidylinositol-3-kinase (PI3K) activity, in particular treating hyper-proliferative and/or angiogenesis mediated disorders, as a sole agent or in combination with other active ingredients. | 08-04-2011 |
20130190332 | Substituted Imidazo[1,2-a]pyrimidines and -pyridines - Compounds of formula (I) which are effective inhibitors of the Pi3K/Akt pathway, processes for their production and their use as pharmaceuticals. | 07-25-2013 |
20130210815 | SUBSTITUTED IMIDAZOPYRAZINES - The present invention relates to substituted imidazopyrazine compounds of general formula (I) in which A, R | 08-15-2013 |
20140213575 | 6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepines - The invention relates to 6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepines, in particular for therapeutic purposes, pharmaceutical agents and use thereof in therapy, in particular for the prevention and treatment of tumour diseases. | 07-31-2014 |
20150080374 | AMINOALCOHOL SUBSTITUTED 2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLINE DERIVATIVES USEFUL FOR TREATING HYPER-PROLIFERATIVE DISORDERS AND DISEASES ASSOCIATED WITH ANGIOGENESIS - This invention relates to novel 2,3-dihydroimidazo[1,2-c]quinazoline compounds, pharmaceutical compositions containing such compounds and the use of those compounds or compositions for phosphotidylinositol-3-kinase (PI3K) inhibition and treating diseases associated with phosphotidylinositol-3-kinase (PI3K) activity, in particular treating hyper-proliferative and/or angiogenesis disorders, as a sole agent or in combination with other active ingredients. | 03-19-2015 |
20150306102 | SUBSTITUTED PYRAZOLOPYRIMIDINES AS AKT KINASE INHIBITORS - Compounds of formula (I) which are effective inhibitors of the Pi3K/Akt pathway, processes for their production and their use as pharmaceuticals. | 10-29-2015 |
20150368250 | IMIDAZOPYRIDAZINES AS AKT KINASE INHIBITORS - Imidazopyridazines of formula (I) | 12-24-2015 |