Patent application number | Description | Published |
20100268904 | APPARATUS AND METHODS FOR REGION LOCK MANAGEMENT ASSIST CIRCUIT IN A STORAGE SYSTEM - Apparatus and methods for improved region lock management in a storage controller. A region lock management circuit coupled with a memory is provided for integration in a storage controller. One or more I/O processor circuits of the storage controller transmit requests to the region lock management circuit to request a temporary lock for a region of storage on a volume of the storage system. The region lock management circuit determines whether the requested lock may be granted or whether it conflicts with other presently locked regions. Presently locked regions and regions to be locked are represented by region lock data structures. In one exemplary embodiment, the region lock data structures for each logical volume may be stored as a tree data structure. A tree assist circuit may also be provided to aid the region lock management circuit in managing the region lock tree data structures. | 10-21-2010 |
20130067123 | METHODS AND STRUCTURE FOR IMPROVED I/O SHIPPING IN A CLUSTERED STORAGE SYSTEM - Methods and structure for improved shipping of I/O requests among multiple storage controllers of a clustered storage system. Minimal processing of a received I/O request is performed in a first controller to determine whether the I/O request is directed to a logical volume that is owned by the first controller or to a logical volume owned by another controller. For requests to logical volumes owned by another controller, the original I/O request is modified to indicate the target device address of the other controller. The first controller then ships the request to the other controller and configures DMA capabilities of the first controller to exchange data associated with the shipped request between the other controller and memory of the host system. | 03-14-2013 |
20130067125 | METHODS AND STRUCTURE FOR IMPROVED PROCESSING OF I/O REQUESTS IN FAST PATH CIRCUITS OF A STORAGE CONTROLLER IN A CLUSTERED STORAGE SYSTEM - Methods and structure for improved processing of fast path I/O requests in a clustered storage system. In a storage controller of a clustered storage system, the controller comprises a fast path I/O request processing circuit tightly coupled with host system drivers for fast processing of requests directed to storage devices of a logical volume. The controller also comprises a logical volume I/O processing stack (typically implemented as programmed instructions) for processing I/O requests from a host system directed to a logical volume. Based on detecting a change of ownership of a device or volume and/or a change to logical to physical mapping of a logical volume, fast path I/O requests may be converted to logical volume requests based on mapping context information within the fast path I/O request and shipped within the clustered storage system for processing. | 03-14-2013 |
20130067164 | METHODS AND STRUCTURE FOR IMPLEMENTING LOGICAL DEVICE CONSISTENCY IN A CLUSTERED STORAGE SYSTEM - Methods and system are provided for exposing logical volumes to host systems and storage controllers in a consistent manner across a clustered storage system. One embodiment is a storage controller. The storage controller is operable to communicate with other storage controllers within the clustered storage system. The storage controller is further operable to generate a proposed Logical Unit Number (LUN) for a logical volume provisioned at the storage devices, and to communicate with each of the other storage controllers within the clustered storage system requesting that the other storage controllers determine if the proposed LUN is in use. If the proposed LUN is not in use, then storage controller assigns the proposed LUN to the logical volume. If the LUN is in use, then the storage controller generates a new proposed LUN and re-tries communication with the other storage controllers until a unique LUN is found. | 03-14-2013 |
20130067172 | METHODS AND STRUCTURE FOR IMPROVED BUFFER ALLOCATION IN A STORAGE CONTROLLER - Methods and structure for improved buffer management in a storage controller. A plurality of processes in the controller each transmits buffer management requests to buffer management control logic. A plurality of reserved portions and a remaining non-reserved portion are defined in a shared pool memory managed by the buffer management control logic. Each reserved portion is defined as a corresponding minimum amount of memory of the shared pool. Each reserved portion is associated with a private pool identifier. Each allocation request from a client process supplies a private pool identifier for the associated buffer to be allocated. The buffer is allocated from the reserved portion if there sufficient available space in the reserved portion identified by the supplied private pool identifier. Otherwise, the buffer is allocated if sufficient memory is available in the non-reserved portion. Otherwise the request is queued for later re-processing. | 03-14-2013 |
20130067569 | METHODS AND STRUCTURE FOR MANAGING VISIBILITY OF DEVICES IN A CLUSTERED STORAGE SYSTEM - Methods and system for implementing a clustered storage solution are provided. One embodiment is a storage controller that communicatively couples a host system with a storage device. The storage controller comprises an interface and a control unit. The interface is operable to communicate with the storage device. The control unit is operable to identify ownership information for a storage device, and to determine if the storage controller is authorized to access the storage device based on the ownership information. The storage controller is operable to indicate the existence of the storage device to the host system if the storage controller is authorized, and operable to hide the existence of the storage device from the host system if the storage controller is not authorized. | 03-14-2013 |
20140164715 | METHODS AND STRUCTURE FOR USING REGION LOCKS TO DIVERT I/O REQUESTS IN A STORAGE CONTROLLER HAVING MULTIPLE PROCESSING STACKS - Methods and structure within a storage controller for using region locks to efficiently divert an I/O request received from an attached host system to one of multiple processing stacks in the controller. A region lock module within the controller allows each processing stack to request a region lock for a range of block addresses of the storage devices. A divert-type lock request may be established to identify a range of block addresses for which I/O requests should be diverted to a particular one of the multiple processing stacks. | 06-12-2014 |
20150113312 | SYSTEM AND METHOD FOR DETECTING SERVER REMOVAL FROM A CLUSTER TO ENABLE FAST FAILOVER OF STORAGE - Aspects of the disclosure pertain to a system and method for detecting server removal from a cluster to enable fast failover of storage (e.g., logical volumes). A method of operation of a storage controller of a cluster is disclosed. The method includes receiving a signal. The method further includes, based upon the received signal, determining that communicative connection between a second storage controller of the cluster and the first storage controller of cluster is unable to be established. The method further includes determining whether communicative connection between the first storage controller and expanders of first and second enclosure services manager modules of the cluster is able to be established. The method further includes, when it is determined that communicative connection between the first storage controller and the expanders of the first and second enclosure services manager modules of the cluster is able to be established, performing a failover process. | 04-23-2015 |
Patent application number | Description | Published |
20080212980 | METHODS AND SYSTEMS FOR POLARIZATION CONTROL AND POLARIZATION MODE DISPERSION COMPENSATION FOR WIDEBAND OPTICAL SIGNALS - An optical processing method includes: receiving an optical signal from an optical system, wherein the optical signal is distorted by frequency-dependent polarization effects in the optical system; spatially dispersing frequency components of the distorted optical signal on a spatial light modulator (SLM); and independently adjusting the polarization transfer matrix of multiple regions of the SLM to reduce the distortion of the optical signal. A related optical processing method includes: providing a precompensation signal indicative of frequency-dependent polarization effects in a downstream optical system; spatially dispersing frequency components of an optical signal on a spatial light modulator (SLM); and independently adjusting the polarization transfer matrix of multiple regions of the SLM to at least partially precompensate the optical signal for distortions caused by the frequency-dependent polarization effects in the downstream optical system. Another related optical processing method includes: providing a model of the frequency-dependent polarization effects; spatially dispersing frequency components of the optical signal on a spatial light modulator (SLM); and independently adjusting the polarization transfer matrix of multiple regions of the SLM based on the model to emulate the optical signal transmission. | 09-04-2008 |
20090285582 | POLARIZATION MODE DISPERSION COMPENSATION - An apparatus and method for correcting for the polarization mode distortion of an optical signal is described. The optical data signal to be transmitted is processed by a switch configured to place the signal into a plurality of polarization states on a periodic basis. At the receiving end of the system, a portion to the signal is coupled to a polarimeter and the wavelength-dependent state of polarization (SOP) of the received signal determined for the plurality of polarization states imposed on the transmitted signal. The data for two of the transmitted polarization states is selected to be used as the basis for correcting the SOP so as to compensate for the wavelength dependence thereof. The corrections may be applied in an optical pulse shaper. | 11-19-2009 |
20090297155 | Wideband microwave and millimeter wave filters using photonic spectral filtering - An apparatus and method is disclosed for producing and filtering optical and electrical waveforms. The apparatus includes an electro-optical modulator, an optical filter capable of modulating at least two spectral regions within the bandwidth of the electrical waveform, and an optical-to-electrical converter. The optical filter includes a spatial dispersion means, a spatial modulating means having the capability to substantially independently modulate a characteristic of each of a pair of optical spatial elements. | 12-03-2009 |
20150072624 | PHASE COMPENSATION FILTERING FOR MULTIPATH WIRELESS SYSTEMS - A wireless communication system is disclosed. The system includes a transmitter which includes a data source configured to provide data to be transmitted, a modulator configured to modulate the data, a pre-filter configured to apply a filter to the modulated data generating pre-filtered data, and a transmitter antenna configured to receive the pre-filtered data and to transmit the pre-filtered data, the pre-filter based on a phase compensation topology that is based on channel characteristics between the transmitter and a receiver, the frequency response of the pre-filter based on spectral phase information of the channel such that the frequency response at the receiver is proportional to the magnitude of the channel frequency response. | 03-12-2015 |
Patent application number | Description | Published |
20120009634 | ALDOLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM - This invention relates to polypeptides having aldolase activity, including pyruvate activity such as, without limitation, HMG and/or KHG aldolase activity, polynucleotides encoding these polypeptides, and methods of making and using these polynucleotides and polypeptides. In some embodiments, the invention is directed to polypeptides having aldolase activity, including pyruvate activity such as, without limitation, HMG and/or KHG aldolase activity, including thermostable and thermotolerant activity, and polynucleotides encoding these enzymes, and making and using these polynucleotides and polypeptides. The polypeptides in accordance with the invention can be used in a variety of pharmaceutical, agricultural and industrial contexts. In some embodiments, the invention provides polypeptides and biosynthetic pathways that are useful in the production of R-2-hydroxy 2-(indol-3ylmethyl)-4-keto glutaric acid (R-MP) and certain stereoisomers of monatin, such as R,R and S, R monatin, and salts thereof, as well as certain stereoisomers of monatin derivatives, such as the R,R and S,R configurations, and salts thereof. | 01-12-2012 |
Patent application number | Description | Published |
20110292676 | Chiral Fiber Apparatus and Method for Controllable Light Extraction from Optical Waveguides - The system and method of the present invention advantageously enable controllable light extraction from optical fiber waveguides and offer highly configurable light signal guidance and control capabilities, as well as additional advantageous features associated with waveguides, by providing, in various exemplary embodiments thereof, a multitude of novel techniques by which the parameters relating to utilization of various light signals (such as direction of their emission, magnitude of the emission, physical surface area of the emission, etc.), can be readily controlled and configured as a matter of design choice. Additionally, the inventive system and method, in various exemplary embodiments thereof, also enable and facilitate selective configuration of, and/or control over, various characteristics of the light signals guided/controlled/extracted thereby, such as the signals' wavelength, polarization, intensity, amplitude, etc. To achieve the above-noted beneficial functions, the system and method of the present invention utilize a physical property of a standard, or a specialty, chiral optical fiber to scatter light signals entering the fiber in directions away from the fiber core (through the fiber cladding), to thereby advantageously enable selective and controllable extraction of light signals of a desired predetermined wavelength (or, optionally of a predetermined range of wavelengths) therefrom. | 12-01-2011 |
20110293219 | Chiral Fiber System and Method for Providing Configurable Light Extraction from Optical Waveguides in Accordance with at Least One Predetermined Light Extraction Profile - The system and method of the present invention advantageously enable controllable light extraction from optical fiber waveguides and offer highly configurable light signal guidance and control capabilities, as well as additional advantageous features associated with waveguides, by providing, in various exemplary embodiments thereof, a multitude of novel techniques by which the parameters relating to utilization of various light signals (such as direction of their emission, magnitude of the emission, physical surface area of the emission, etc.), can be readily controlled and configured as a matter of design choice. Additionally, the inventive system and method, in various exemplary embodiments thereof, also enable and facilitate selective configuration of, and/or control over, various characteristics of the light signals guided/controlled/extracted thereby, such as the signals' wavelength, polarization, intensity, amplitude, etc. The system and method of the present invention further advantageously provide various embodiments of the novel optical fiber waveguides with one or more selected desirable and useful light extraction profiles, that may be configured as a matter of design choice in connection with the intended purpose, and/or the desired functionality, of the corresponding fiber waveguide component(s). | 12-01-2011 |
Patent application number | Description | Published |
20110044902 | Modulation of the Immune Response - Methods for identifying compounds that modulate the generation of regulatory T cells (Treg) in vivo and in vitro, i.e., compounds that act on the transcription factors that increase or decrease expression of Foxp3. | 02-24-2011 |
20110262457 | MODULATION OF THE IMMUNE RESPONSE - Methods for increasing the generation of IL-17-producing T cells (T | 10-27-2011 |
20120077770 | Methods of Diagnosing and Treating Multiple Sclerosis - Methods of using a 15-oxysterol, e.g., 15-ketocholestene (15-KE), 15-ketocholestane (15-KA), and/or 15-hydroxy-cholestene (15-HC), as a biomarker to monitor disease progression in multiple sclerosis (MS), and methods of treating secondary progressive MS (SPMS) using inhibitors of poly(ADP ribose) polymerase-1 (PARP-1). | 03-29-2012 |
20120202870 | TREATMENT OF INFLAMMATORY DISEASES USING MIR-124 - Methods of treating, reducing the risk of developing, or delaying the onset of an inflammatory disease are disclosed. The methods involved providing a subject with or at risk of developing an inflammatory disease and administering to the subject an effective amount of a first therapeutic composition comprising miR-124. Further provided are methods of diagnosing a subject with or at risk of developing an inflammatory disease. | 08-09-2012 |
20130183245 | METHODS OF TREATING CEREBRAL AMYLOID ANGIOPATHY - Methods for treating and reducing risk of cerebral amyloid angiopathy (CAA) using nasal vaccination with a proteosome adjuvant. | 07-18-2013 |
20130336993 | Modulation of the Immune Response - Methods for identifying compounds that modulate the generation of regulatory T cells (Treg) in vivo and in vitro, i.e., compounds that act on the transcription factors that increase or decrease expression of Foxp3. | 12-19-2013 |
20140178367 | Methods of Treating Inflammatory Diseases by Targeting the Chemoattractant Cytokine Receptor 2 (CCR2) or Chemokine (C-C motif) Ligand 2 (CCL2) - Methods of treating inflammatory diseases, e.g., diseases associated with inflammatory CD14+/CD16− monocytes, e.g., amyotrophic lateral sclerosis (ALS), stroke, and glaucoma, using compounds such as small molecules and antibodies that target CCR2 or CCL2. | 06-26-2014 |
20140235697 | MICRORNAS IN NEURODEGENERATIVE DISORDERS - The invention provides methods for diagnosing neurodegenerative disorders (e.g., amyotrophic lateral sclerosis and multiple sclerosis) in a subject, identifying subjects at risk of developing a neurodegenerative disorder, predicting the rate of disease progression in a subject having a neurodegenerative disorder, selecting a subject for treatment of a neurodegenerative disorder, selecting a subject for participation in a clinical study, and determining the efficacy of treatment of a neurodegenerative disorder. These methods include determining the level of one or more microRNAs and/or one or more inflammatory markers in a monocyte (e.g., a CD14 | 08-21-2014 |
20140343095 | Methods of Diagnosing and Treating Multiple Sclerosis - Methods of using a 15-oxysterol, e.g., 15-ketocholestene (15-KE), 15-ketocholestane (15-KA), and/or 15-hydroxy-cholestene (15-HC), as a biomarker to monitor disease progression in multiple sclerosis (MS), and methods of treating secondary progressive MS (SPMS) using inhibitors of poly(ADP ribose) polymerase-1 (PARD-1). | 11-20-2014 |
20150064197 | METHODS OF MODULATING IMMUNITY - The invention provides novel methods of administering anti-CD3 antibodies, e.g., via oral or mucosal delivery. The invention also provides methods of treating, preventing, or delaying the onset of autoimmune disorders by oral or mucosal administration of anti-CD3 antibodies. Finally, the invention provides compositions including anti-CD3 antibodies, suitable for oral or mucosal administration. | 03-05-2015 |
20150202231 | Modulation of the Immune Response - Methods for increasing the numbers of regulatory T cells (Treg), e.g., in a population of T cells or in a patient. | 07-23-2015 |
Patent application number | Description | Published |
20100144868 | Novel Neuroprotective Compounds and Uses Thereof - Disclosed are novel hybrid compounds having a fullerene core residue, one or more bioavailability enhancing moieties and one or more glutamate receptor ligand residues, whereby the bioavailability enhancing moiety allow the compound to reach an effective concentration in physiological media and pass the blood-brain barrier, as defined in the specification. Also disclosed are pharmaceutical compositions containing these hybrid compounds and uses thereof as antioxidants and/or neuroprotective agents for the treatment of medical conditions associated with oxidative stress and/or neural damage, such as, for example, neurological diseases, disorders and trauma, and hence in the treatment of CNS-associated diseases, disorders and trauma, as well as to uses thereof as antiviral, antibacterial, antiglycemic, antiarrhythmic, antidepressant and antitumor agents. | 06-10-2010 |
20110165177 | Methods of Modulating Immunity - The invention provides novel methods of administering anti-CD3 antibodies, e.g., via oral or mucosal delivery. The invention also provides methods of treating, preventing, or delaying the onset of autoimmune disorders by oral or mucosal administration of anti-CD3 antibodies. Finally, the invention provides compositions including anti-CD3 antibodies, suitable for oral or mucosal administration. | 07-07-2011 |
20110200617 | COMBINATION THERAPY OF BETA-GLYCOLIPIDS AND ANTIBODIES FOR THE TREATMENT OF IMMUNE-RELATED DISORDERS - The present invention relates to a combination therapy for the treatment of immune-related disorders. More particularly, the invention relates to oral or mucosal synergistic compositions combining beta-glycolipids, preferably, β-glycosphingolipids with immunoglobulin molecules specific for at least one antigen derived from a component of the immune system, specifically an anti-CD3 antibody. The invention further provides methods kits and uses of the combined compositions of the invention for immuno-modulation and thereby for the treatment of immune-related disorders. In a preferred embodiment, anti-CD3 anti-body (OKT3) is orally administered in combination with β-glucosylceramide (also known as glycocerebroside) in an animal model of type 2 diabetes. | 08-18-2011 |
20120077686 | DIAGNOSIS OF MULTIPLE SCLEROSIS - The present invention relates to methods and kits for diagnosing multiple sclerosis (MS) in a subject. Particularly, the present invention relates to methods and kits for diagnosing a subtype of MS in a subject, the subtype selected from relapsing-remitting MS (RRMS), secondary progressive MS (SPMS), primary progressive MS (PPMS) and a pathologic sub-type of MS lesions selected from Pattern I and Pattern II MS lesion. | 03-29-2012 |
20140255420 | Combination Therapy of Beta-Glycolipids and Antibodies for the Treatment of Immune-Related Disorders - The present invention relates to a combination therapy for the treatment of immune-related disorders. More particularly, the invention relates to oral or mucosal synergistic compositions combining beta-glycolipids, preferably, β-glycosphin-golipids with immunoglobulin molecules specific for at least one antigen derived from a component of the immune system, specifically an anti-CD3 antibody. The invention further provides methods kits and uses of the combined compositions of the invention for immune-modulation and thereby for the treatment of immune-related disorders. In a preferred embodiment, anti-CD3 antibody (OKT3) is orally administered in combination with β-glucosylceramide (also known as glycocerebroside) in an animal model of type 2 diabetes. | 09-11-2014 |
Patent application number | Description | Published |
20090327117 | Apparatus and Method for Trade Aggregation of Trade Allocations and Settlements - A post-trade aggregation system includes an allocation middleware interface, which interacts with an order management system to allocate and settle trades. The order management system receives a trade order on behalf of a customer and either apportions the trade into a plurality of smaller orders and communicates them to a plurality of order destinations directly (e.g. via the FIX protocol), or sends large orders to an order staging and optimization interface which then apportions the larger orders into a plurality of smaller orders and communicates the orders to a plurality of order destinations. The post-trade aggregation system contains an allocation middleware interface which receives the individual trade executions from the plurality of order destination and compresses them into a single average-priced block. The allocation middleware interface then sends the single average-priced block to be cleared by a designated clearing agent and allocates the single average-priced block into one or more custodian accounts. In further aspects, a method and apparatus are also provided. | 12-31-2009 |
20100332375 | Apparatus and Method for Trade Aggregation of Trade Allocations and Settlements - A post-trade aggregation system includes an allocation middleware interface, which interacts with an order management system to allocate and settle trades. The order management system receives a trade order on behalf of a customer and either apportions the trade into a plurality of smaller orders and communicates them to a plurality of order destinations directly (e.g. via the FIX protocol), or sends large orders to an order staging and optimization interface which then apportions the larger orders into a plurality of smaller orders and communicates the orders to a plurality of order destinations. The post-trade aggregation system contains an allocation middleware interface which receives the individual trade executions from the plurality of order destination and compresses them into a single average-priced block. The allocation middleware interface then sends the single average-priced block to be cleared by a designated clearing agent and allocates the single average-priced block into one or more custodian accounts. In further aspects, a method and apparatus are also provided. | 12-30-2010 |
20130144773 | APPARATUS AND METHOD FOR TRADE AGGREGATION OF TRADE ALLOCATIONS AND SETTLEMENTS - A post-trade aggregation system for financial instrument trading systems, wherein a trader manages a plurality of trade orders to be executed by one or more executing brokers on behalf of customers via a data interface system. The plurality of trade orders includes at least one wrap block order and at least one institutional block order. The plurality of trade orders are merged into a single merged block order, apportioned into a plurality of smaller electronic trade orders, and transmitted to a plurality of order destinations. One or more computer systems are in electronic communication with the data interface system and with a clearing system, and configured to compress individual executions from the plurality of order destinations corresponding to the plurality of smaller electronic trade orders into a single net marked-up step-out for wrap orders and a single average-priced block for institutional orders. | 06-06-2013 |
20150178839 | APPARATUS AND METHOD FOR TRADE AGGREGATION OF TRADE ALLOCATIONS AND SETTLEMENTS - A post-trade aggregation system includes an allocation middleware interface, which interacts with data interface to allocate and settle trades. An order management system receives a trade order on behalf of a customer and causes apportionment of the trade into a plurality of smaller orders to be transmitted to a plurality of order destinations directly (e.g. via the FIX protocol). The post-trade aggregation system includes an allocation middleware interface which receives the individual trade executions from the plurality of order destination and compresses them into a single average-priced block. The allocation middleware interface then transmits the single average-priced block to be cleared by a designated clearing agent and allocates the single average-priced block into one or more custodian accounts. | 06-25-2015 |
Patent application number | Description | Published |
20110004255 | BONE JOINING APPARATUS AND METHOD - Provided is a bone joining device suitable for joining a first bone piece to a second bone piece. Also provided is a method of joining a first bone piece with a second bone piece in a living mammal. The method comprises inserting the above bone joining device between the first bone piece and the second bone piece. | 01-06-2011 |
20110230885 | DYNAMIC BONE PLATE - A plate for adjusting the position of a first piece of bone with respect to a second piece of bone, comprising a first section comprising a first upper exterior surface, a first lower exterior surface, a first outer edge, a first distal end, a first coupling end across the first section from the first distal end, at least one first section bone screw hole, and a first bone screw in the at least one first section bone screw hole, a second section comprising a second upper exterior surface, a second lower exterior surface, a second outer edge, a second distal end, a second coupling end across the second section from the second distal end, at least one second section bone screw hole, and a second bone screw in the at least one second section bone screw hole, and a gear deposed between the first section and the second section. | 09-22-2011 |
20140039561 | BONE FIXATION DEVICE AND METHOD - In a method and system for corrective surgery of a bone, a bone is cut into a first bone segment and a second bone segment. A plate is positioned over the first bone segment and the second bone segment such that at least one member of the plate is positioned to engage the second bone segment. The at least one member of the plate is inserted into the second bone segment. At least one bone screw is screwed into the first bone segment through at least one compression slot of the plate causing an application of compressive force to secure the first bone segment and the second bone segment to form a corrective construct. The at least one member is positioned at an angle or an offset from the second plate segment | 02-06-2014 |
Patent application number | Description | Published |
20090099565 | Method Of Fracture Fixation - An external fixator includes a main body and an outrigger for extending over a fractured joint, such as a wrist joint. The main body can be positioned next to a right arm, or flipped over and positioned next to a left arm. The outrigger is attachable to extend either to the left or to the right of the main body, as appropriate. A distal body is removeably connectable to the distal end of the main body, and the distal body can be affixed to bone on the opposite side of the fracture to immobilize the joint where the fracture occurs. The distal body is connected to the main body with an adjustable securement section which provides six degrees of adjustment freedom. The outrigger is attached to the main body through a slide plate in a dual rail configuration which provides two dimensions of adjustment. Fragment pin supports ride in a track of the outrigger, and provide seven degrees of adjustment freedom for directed fixation of fragments at the fracture site. The outrigger is pivotally adjustable relative to the main body, and includes track portions separated by a wrap around angle. The major components of the fixator are molded of plastic. A surgical technique using the fixator includes immobilizing the joint for an initial healing duration and retaining fragment pins in place during a secondary healing duration. | 04-16-2009 |
20120303033 | BONE DEFECT REPAIR DEVICE AND METHOD - In a method and system for corrective bunionectomy surgery of a bone, a saw template is positioned at a proximal portion of the bone. The saw template has a plurality of pin holes, for the insertion of pins. The saw template is replaced with a saw block placed over a portion of the plurality of pins. The bone is cut into first and second bone segments based on a position of the saw block. The saw block is removed. A corrective angle is applied to the second bone segment relative to the first bone segment. A mating plate compatible with the corrective angle is positioned over the plurality of pins to join the first bone segment and the second bone segment. A plurality of bone screws is screwed into the mating plate to secure the first bone segment and the second bone segment to form a corrective construct. | 11-29-2012 |
20130006247 | BONE PLATE HYBRID DEVICE - A method for joining of biological elements is disclosed. A plate is placed over a first segment and a second segment. The plate is attached to the first segment and the second segment. A dowel channel is drilled thru a dowel hole of the plate. A dowel is inserted into the dowel channel, wherein the dowel crosses a joining plane of the first segment and the second segment. A locking screw is placed on a top side of the dowel to lock the dowel in place. | 01-03-2013 |
20130030475 | REVERSIBLE BONE COUPLING DEVICE AND METHOD - A reversible bone coupling device including a first component having a first elongated stem portion for insertion from a first end longitudinally into a surface of a first bone piece, and a second component having a second elongated stem portion for insertion from a second end longitudinally into a surface of a second bone piece, and a connector extending from a second top for coupling with the first component and reversibly locking therein. | 01-31-2013 |
20130274814 | BONE JOINING APPARATUS AND METHOD - Provided is a bone joining device suitable for joining a first bone piece to a second bone piece. Also provided is a method of joining a first bone piece with a second bone piece in a living mammal. The method comprises inserting the above bone joining device between the first bone piece and the second bone piece. | 10-17-2013 |
20140214036 | DYNAMIC BONE PLATE COMPRESSION DEVICE AND METHOD - A dynamic bone plate and method of bone compression is disclosed. The dynamic bone plate comprises a first bone plate component and a second bone plate component. The first bone plate component comprises at least one hole configured for receiving bone screws for attachment to a first bone segment; and a male component. The second bone plate component comprises at least one hole configured for receiving bone screws for attachment to a second bone segment; and a female component configured for mating with the male component of the first bone plate component. The male component is adjustable after mating with the female component to adjust a position of the first bone plate component with respect to the second bone plate component and wherein the male component is locked into place with respect to the female component by at least one bone screw inserted through the at least one hole of the second bone plate component causing compression between the first bone segment and the second bone segment to form a corrective construct. | 07-31-2014 |
20140243910 | BONE JOINING APPARATUS AND METHOD - Provided is a bone joining device suitable for joining a first bone piece to a second bone piece. Also provided is a method of joining a first bone piece with a second bone piece in a living mammal. The method comprises inserting the above bone joining device between the first bone piece and the second bone piece. | 08-28-2014 |
20150245858 | BONE SHORTENING DEVICE AND METHOD - Bone fixation devices and plates are disclosed. The bone fixation device includes a first portion, a second portion, and a third portion. The first portion includes at least one opening. The second portion includes at least one second opening. The third portion is positioned between the first portion and the second portion and is configured to guide the cutting of a bone. The bone fixation plate includes a first plate portion, a second plate portion, and a third plate portion. The first plate portion includes at least one screw hole for receiving a first bone screw. The second plate portion includes at least one slot for receiving a second bone screw. The third plate portion is positioned adjacent to the first and second plate portions and is configured to guide bone cutting A method of altering a bone using the bone fixation devices and plates is also disclosed. | 09-03-2015 |
20150272640 | BONE PLATE HYBRID DEVICE - A method for joining of biological elements is disclosed. A plate is placed over a first segment and a second segment. The plate is attached to the first segment and the second segment. A dowel channel is drilled thru a dowel hole of the plate. A dowel is inserted into the dowel channel, wherein the dowel crosses a joining plane of the first segment and the second segment. A locking screw is placed on a top side of the dowel to lock the dowel in place. | 10-01-2015 |
Patent application number | Description | Published |
20080221634 | Fibrillation/Tachycardia Monitoring and Preventive System and Methodology - A cardiac assist device senses conditions of a heart and controls the generation of various electrical stimuli in response to sense conditions of the heart. The cardiac assist device generates a electrical pulse so as to defibrillate a fibrillated heart when the cardiac assist device determines from the sensed conditions a state of fibrillation. The cardiac assist device generates a chaos control electrical signal so as to bring a pre-fibrillated heart condition back into a normal beating condition when the cardiac assist device determines from the sensed conditions a pre-state of fibrillation. Lastly, the cardiac assist device generates an electrical enhancement signal that causes a threshold of pacing cells in the heart to be exceeded in response to a subthreshold stimulus when the cardiac assist device determines from the sensed conditions a subthreshold pacing signal. | 09-11-2008 |
20080280353 | Hybrid nucleic acid assembly - A detection device comprised of a hybrid nucleic acid assembly. The device further comprises a nucleic acid polymer, a first nanoparticle conjugated to the nucleic acid polymer, a second nanoparticle conjugated with the nucleic acid polymer, a means for introducing energy into the first nanoparticle, means for detecting energy from the second nanoparticle, and means for determining a physical property of the nucleic acid polymer, wherein the means of introducing energy into the first nanoparticle is a source of mechanical energy. | 11-13-2008 |
20080287856 | Process and apparatus for treating biological organisms - An apparatus for treating a biological organism comprising a device for emitting and delivering energy to the biological organism, a programmable controller for varying the type and amount of energy emitted, and apparatus for sensing a condition of the biological organism. | 11-20-2008 |
20120158080 | MRI-COMPATIBLE IMPLANTABLE DEVICE - A medical device containing a device for connecting the medical device to a substrate, for furnishing electrical impulses from the medical device to the substrate, for ceasing the furnishing of electrical impulses to the substrate, for receiving pulsed radio frequency fields, for transmitting and receiving optical signals, and for protecting the substrate and the medical device from currents induced by the pulsed radio frequency fields. The medical device contains a control circuit comprised of a parallel resonant frequency circuit. | 06-21-2012 |
20130218250 | MRI-compatible implantable device - A medical device containing a device for connecting the medical device to a substrate, for furnishing electrical impulses from the medical device to the substrate, for ceasing the furnishing of electrical impulses to the substrate, for receiving pulsed radio frequency fields, for transmitting and receiving optical signals, and for protecting the substrate and the medical device from currents induced by the pulsed radio frequency fields. The medical device contains a control circuit comprised of a parallel resonant frequency circuit. | 08-22-2013 |
Patent application number | Description | Published |
20100137147 | System, method, and product for multiple wavelength detection using single source excitation - An embodiment of a method for adjusting system gain of a biological probe array scanner for a plurality of fluorophore species is described that comprises setting an excitation beam comprising an excitation wavelength at a first power level that elicits an optimal signal to noise ratio response from a first fluorophore species; scanning a biological probe array with the excitation beam; setting the excitation beam comprising the excitation wavelength at a second power level different than the first power level that elicits the optimal signal to noise ratio response from a second fluorophore species; and scanning the biological probe array with the excitation beam. | 06-03-2010 |
20100142850 | System, method, and product for scanning of biological materials - An embodiment of a scanning system is described including optical elements that direct an excitation beam at a probe array, detectors that receive reflected intensity data responsive to the excitation beam, where the reflected intensity data is responsive to a focusing distance between an optical element and the probe array, a transport frame that adjusts the focusing distance in a direction with respect to the probe array, an auto-focuser that determines a best plane of focus based upon characteristics of the reflected intensity data of at least two focusing distances where the detectors further receive pixel intensity values based upon detected emissions from a plurality of probe features disposed on the probe array at the best plane of focus, and an image generator that associates each of the pixel intensity values with at least one image pixel position of a probe array based upon one or more position correction values. | 06-10-2010 |
20100260012 | SYSTEM AND METHOD FOR CONTROLLING AN ACOUSTIC TRANSDUCER - A system and method for controlling operation of a transducer circuit, e.g., including an acoustic transducer arranged to cause mixing, cavitation or other movement in a liquid contained in a vessel located remote from the transducer. A load current of a transformer used to generate a drive signal for the transducer may be controlled to vary sinusoidally, to vary between negative and positive values and such that the load current flows in a closed loop when a zero voltage bias is applied across the primary transformer winding, to have a reduced or eliminated 3 | 10-14-2010 |
20110243411 | System, method, and product for scanning of biological materials - An embodiment of a scanning system is described including optical elements that direct an excitation beam at a probe array, detectors that receive reflected intensity data responsive to the excitation beam, where the reflected intensity data is responsive to a focusing distance between an optical element and the probe array, a transport frame that adjusts the focusing distance in a direction with respect to the probe array, an auto-focuser that determines a best plane of focus based upon characteristics of the reflected intensity data of at least two focusing distances where the detectors further receive pixel intensity values based upon detected emissions from a plurality of probe features disposed on the probe array at the best plane of focus, and an image generator that associates each of the pixel intensity values with at least one image pixel position of a probe array based upon one or more position correction values. | 10-06-2011 |
20120235016 | System, Method, and Product for Scanning of Biological Materials - An embodiment of a scanning system is described including optical elements that direct an excitation beam at a probe array, detectors that receive reflected intensity data responsive to the excitation beam, where the reflected intensity data is responsive to a focusing distance between an optical element and the probe array, a transport frame that adjusts the focusing distance in a direction with respect to the probe array, an auto-focuser that determines a best plane of focus based upon characteristics of the reflected intensity data of at least two focusing distances where the detectors further receive pixel intensity values based upon detected emissions from a plurality of probe features disposed on the probe array at the best plane of focus, and an image generator that associates each of the pixel intensity values with at least one image pixel position of a probe array based upon one or more position correction values. | 09-20-2012 |
Patent application number | Description | Published |
20080293115 | PLANT WALL DEGRADATIVE COMPOUNDS AND SYSTEMS - The present invention relates to cell wall degradative systems, in particular to systems containing enzymes that bind to and/or depolymerize cellulose. These systems have a number of applications. | 11-27-2008 |
20090053776 | ENZYMIC PRODUCTION OF NEOAGAROBIOSE - The present invention is directed to methods and systems of producing neoagarobiose, useful in whitening melanoma cells and in cosmetics, using polypeptides having neoagarobiosebiohydralase activity, including Aga86E from | 02-26-2009 |
20100159563 | Preparation and use of biofilm-degrading, multiple-specificity, hydrolytic enzyme mixtures - The present invention relates to isolated structures containing degradative enzymes produced from a marine organism. The enzymes produced are based on the carbon source upon which the marine organism is growing. The enzymes are found in structures that can be isolated such that the degradative enzymes are easily harvested. | 06-24-2010 |
20120329103 | PLANT WALL DEGRADATIVE COMPOUNDS AND SYSTEMS - The present invention relates to cell wall degradative systems, in particular to systems containing enzymes that bind to and/or depolymerize cellulose. These systems have a number of applications. | 12-27-2012 |
20130196401 | HYDROLYTIC ENZYME MIXTURES FOR SACCHARIFICATION OF LIGNOCELLULOSIC POLYSACCHARIDES - The present invention relates to cell wall degradative systems, in particular to systems containing enzymes that bind to and/or depolymerize cellulose. These systems have a number of applications. Some embodiments relate to a method of producing ethanol using the cell wall degradative systems of the present invention. | 08-01-2013 |
20140113351 | PREPARATION AND USE OF BIOFILM-DEGRADING, MULTIPLE-SPECIFICITY, HYDROLYTIC ENZYME MIXTURES - The present invention relates to isolated structures containing degradative enzymes produced from a marine organism. The enzymes produced are based on the carbon source upon which the marine organism is growing. The enzymes are found in structures that can be isolated such that the degradative enzymes are easily harvested. | 04-24-2014 |
20140248688 | PLANT WALL DEGRADATIVE COMPOUNDS AND SYSTEMS - The present invention relates to cell wall degradative systems, in particular to systems containing enzymes that bind to and/or depolymerize cellulose. These systems have a number of applications. | 09-04-2014 |
Patent application number | Description | Published |
20110173359 | COMPUTER-IMPLEMENTED METHOD AND SYSTEM FOR SECURITY EVENT TRANSPORT USING A MESSAGE BUS - A computer-implemented device provides security events from publishers to subscribers. There is provided a message bus, configured to contain a plurality of security events. Also provided is a receiver unit, responsive to a plurality of publishers, to receive the plurality of security events from the publishers. There is also a queue unit, responsive to receipt of the security events, to queue the plurality of security events in the message bus. Also, there is a transport unit, responsive to the security events in the message bus, to transport the plurality of security events in the message bus to a plurality of subscribers. | 07-14-2011 |
20110296015 | EVENT SOURCE MANAGEMENT USING A METADATA-DRIVEN FRAMEWORK - The system and method described herein relates to managing multiple network device connections, collecting event source data from one or more network devices with one or more collectors, filtering the event source data, continuously monitoring the network device connections, controlling raw data collection from the one or more network devices, parsing the event source data into normalized data structures, and managing configurations for the collectors, among other things. Event sources may be physical or logical network devices distributed across a network, including but not limited to, firewalls, routers, biometric devices, mainframes, databases, and applications. The network devices may be sources from which the collectors may receive or request the event source data. | 12-01-2011 |
20150263895 | EVENT SOURCE MANAGEMENT USING A METADATA-DRIVEN FRAMEWORK - The system and method described herein relates to managing multiple network device connections, collecting event source data from one or more network devices with one or more collectors, filtering the event source data, continuously monitoring the network device connections, controlling raw data collection from the one or more network devices, parsing the event source data into normalized data structures, and managing configurations for the collectors, among other things. Event sources may be physical or logical network devices distributed across a network, including but not limited to, firewalls, routers, biometric devices, mainframes, databases, and applications. The network devices may be sources from which the collectors may receive or request the event source data. | 09-17-2015 |