Warzecha
Claude Warzecha, Philadelphia, PA US
Patent application number | Description | Published |
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20110177967 | METHODS AND COMPOSITIONS USING SPLICING REGULATORY PROTEINS INVOLVED IN TUMOR SUPPRESSION - Methods and compositions for diagnosis and prognosis of mammalian carcinoma or cancer derived from primary epithelial cells and tissue fibrosis are designed using newly identified epithelial cell-type specific splicing factors ESRP1 and ESRP2, which have roles in tumor suppression. Diagnostic reagents for the detection of these splicing factors in nucleotide or protein form are useful in such methods. Therapeutic compositions can provide epithelial cells with these factors to maintain FGFR2 and assist in suppressing metastasis. A high throughput splicing assay to identify compounds that change splicing events is described. RNCP1 is also identified as a splicing factor and a diagnostic for conditions characterized by inappropriate FGFR2-splicing. | 07-21-2011 |
Michael R. Warzecha, Longmont, CO US
Patent application number | Description | Published |
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20090082766 | Tissue Sealer and End Effector Assembly and Method of Manufacturing Same - A bipolar forceps for sealing tissue includes at least one shaft having an end effector assembly disposed at a distal end thereof. The end effector assembly includes a pair of first and second opposing jaw members movable relative to one another from a first position wherein the jaw members are disposed in spaced relation relative to one another to a second position wherein the jaw members cooperate to grasp tissue therebetween. At least the first jaw member includes proximal and distal ends which define a cavity along a length thereof which houses an insulative member therein. The insulative member includes an electrically conductive sealing surface mounted thereto which resides in substantial opposition with a second electrically conductive sealing surface disposed on the second jaw member. One end of the first jaw member which defines the cavity extends a fixed distance toward the second jaw member to form a gap between electrically conductive surfaces when the jaw members are closed to grasp tissue. | 03-26-2009 |
20090082767 | Tissue Sealer and End Effector Assembly and Method of Manufacturing Same - A method for manufacturing an end effector assembly for sealing tissue includes the initial step of providing a pair of first and second jaw members each including an inwardly facing electrically conductive sealing surface. The method also includes the steps of: coating the inwardly facing electrically conductive sealing surface of one or both jaw members with an insulative material, the coating having a thickness within the range of about 0.001 inches to about 0.010 inches; allowing the insulative material to cure onto the inwardly facing electrically conductive sealing surface; removing a portion of the insulative material from the inwardly facing electrically conductive sealing surface to form a series of stop members arranged thereacross; and assembling the pair of first and second jaw members about a pivot such that the two inwardly facing electrically conductive sealing surfaces are substantially opposed to each other in pivotal relation relative to one another. | 03-26-2009 |
20090082769 | Tissue Sealer and End Effector Assembly and Method of Manufacturing Same - A method for manufacturing an end effector assembly for sealing tissue includes the initial step of providing first and second electrically conductive sealing plates. The method also includes the steps of: encasing at least one of the electrically conductive sealing plates in a substantially moldable insulative material; applying a load to the electrically conductive sealing plates; allowing the insulative material to deform to create a gap between the sealing plates between about 0.001 inches to about 0.010 inches; and allowing the insulative material to cure. | 03-26-2009 |
Volker Warzecha, Bad Aibling DE
Patent application number | Description | Published |
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20160069733 | TRANSPORT RAIL SYSTEM WITH WEIGHING MEANS - Transport rail system capable of detecting a weight of a rail vehicle, includes one or more rails, and one or more sensors for measuring a magnetic property. At least one of the sensors is adapted to measure a change of a magnetic property in order to determine a weight bearing on one or more of the rails, the change of the magnetic property being caused by stress exerted on the rail by the weight, and one or more of the sensors are adapted to measure the change of a magnetic property of the rail itself and/or that one or more of the sensors are adapted to measure the change of a magnetic property of a supporting structure of the rail. | 03-10-2016 |