Patent application number | Description | Published |
20090142602 | APPLIANCE TRANSPARENCY - A transparency includes a substrate having a first major surface and a second major surface. A first coating is provided over at least a portion of the first major surface, the first coating including one or more metal oxide layers. A second coating is provided over at least a portion of the second major surface, the second coating including one or more metallic layers. | 06-04-2009 |
20090197097 | APPLIANCE WITH COATED TRANSPARENCY - An appliance transparency includes a first substrate defining a No. 1 and a No. 2 surface and a second substrate spaced from the first substrate and defining a No. 3 and a No. 4 surface. A first coating is deposited over at least a portion of the No. 2 surface and is free of metallic layers. A second coating is deposited over at least a portion of the No. 4 surface and has at least one metallic layer. A protective coating is deposited over at least a portion of the second coating. | 08-06-2009 |
20090233037 | REFLECTIVE ARTICLE HAVING MULTIPLE REFLECTIVE COATINGS - A reflective article, such as a solar mirror, includes a highly transparent substrate having a first major surface and a second major surface. At least one reflective coating is formed over at least a portion of one of the surfaces, e.g., the second major surface (or, alternatively, the first major surface). The reflective coating includes at least one metallic layer. An encapsulation structure can be formed over at least a portion of the second reflective coating. | 09-17-2009 |
20090233071 | REFLECTIVE ARTICLE - A reflective article, such as a solar mirror, includes a highly transparent substrate having a first major surface and a second major surface. At least one reflective coating is formed over at least a portion of one of the surfaces, e.g., the second major surface (or, alternatively, the first major surface). The reflective coating includes at least one metallic layer. An encapsulation structure can be formed over at least a portion of the second reflective coating. | 09-17-2009 |
20090233106 | REFLECTIVE ARTICLE AND METHOD OF MAKING A REFLECTIVE ARTICLE - A reflective article, such as a solar mirror, includes a highly transparent substrate having a first major surface and a second major surface. At least one reflective coating is formed over at least a portion of one of the surfaces, e.g., the second major surface (or, alternatively, the first major surface). The reflective coating includes at least one metallic layer. An encapsulation structure can be formed over at least a portion of the second reflective coating. | 09-17-2009 |
20110117300 | SOLAR CONTROL COATING WITH HIGH SOLAR HEAT GAIN COEFFICIENT - A coating provides a high solar heat gain coefficient (SHGC) and a low overall heat transfer coefficient (U-value) to trap and retain solar heat. The coating and coated article are particularly useful for use in architectural transparencies in northern climates. The coating includes a first dielectric layer; a continuous metallic layer formed over at least a portion of the first dielectric layer, the metallic layer having a thickness less than 8 nm; a primer layer formed over at least a portion of the metallic layer; a second dielectric layer formed over at least a portion of the primer layer; and an overcoat formed over at least a portion of the second dielectric layer. When used on a No. 3 surface of a reference IGU, the coating provides a SHGC of greater than or equal to 0.6 and a U-value of less than or equal to 0.35. | 05-19-2011 |
20110236715 | SOLAR CONTROL COATINGS WITH DISCONTINUOUS METAL LAYER - An architectural transparency includes a substrate, a first dielectric layer formed over at least a portion of the substrate, a continuous metallic layer formed over at least a portion of the first dielectric layer, a second dielectric layer formed over at least a portion of the first metallic layer, and a subcritical metallic layer formed over at least a portion of the second dielectric layer such that the subcritical metallic layer forms discontinuous metallic regions. | 09-29-2011 |
20110240009 | MIRROR HAVING REFLECTIVE COATINGS ON A FIRST SURFACE AND AN OPPOSITE SECOND SURFACE - A solar mirror includes an opaque reflective coating on a surface of a transparent substrate facing away from the sun and a transparent reflective coating on the opposite surface of the substrate. The transparent reflective coating increases the percent reflection of wavelengths in selected ranges, e.g. wavelengths in the infrared range to increase the total solar energy reflected by the solar mirror to increase the solar energy directed to a receiver that converts solar energy to electric and/or thermal energy. | 10-06-2011 |
20130163075 | REFLECTIVE ARTICLE HAVING MULTIPLE REFLECTIVE COATINGS - A reflective article, such as a solar mirror, includes a highly transparent substrate having a first major surface and a second major surface. At least one reflective coating is formed over at least a portion of one of the surfaces, e.g., the second major surface (or, alternatively, the first major surface). The reflective coating includes at least one metallic layer. An encapsulation structure can be formed over at least a portion of the second reflective coating. | 06-27-2013 |
20140193616 | Tempered And Non-Tempered Glass Coatings Having Similar Optical Characteristics - Temperable and non-temperable coatings are provided which have similar optical characteristics. The non-temperable coating is placed on glass that is not to be tempered and provides certain optical characteristics. The temperable coating is placed on a glass substrate and the coated substrate is then tempered. After tempering, the coated tempered glass sheet and the coated non-tempered glass sheet have similar optical characteristics. Both coatings have a plurality of metal layers, with at least one of the metallic layers being a discontinuous layer with a primer layer over the discontinuous metal layer. For the non-temperable coating, the discontinuous metal layer has an effective thickness in the range of 1.5 nm to 1.7 nm. For the temperable coating, the discontinuous metal layer has an effective thickness in the range of 1.7 nm to 1.8 nm. The primer layer of the temperable coating is thinner than the primer layer of the non-temperable coating. | 07-10-2014 |
20140272453 | Solar Control Coatings Providing Increased Absorption Or Tint - A coated article includes a substrate, a first dielectric layer, a subcritical metallic layer having discontinuous metallic regions, a primer over the subcritical layer, and a second dielectric layer over the primer layer. The primer can be a nickel-chromium alloy. The primer can be a multilayer primer having a first layer of a nickel-chromium alloy and a second layer of titania. | 09-18-2014 |
20150191393 | TEMPERED AND NON-TEMPERED GLASS COATINGS HAVING SIMILAR OPTICAL CHARACTERISTICS - Temperable and non-temperable coatings are provided which have similar optical characteristics. The non-temperable coating is placed on glass that is not to be tempered and provides certain optical characteristics. The temperable coating is placed on a glass substrate and the coated substrate is then tempered. After tempering, the coated tempered glass sheet and the coated non-tempered glass sheet have similar optical characteristics. Both coatings have a plurality of metal layers, with at least one of the metallic layers being a discontinuous layer with a primer layer over the discontinuous metal layer. For the non-temperable coating, the discontinuous metal layer has an effective thickness in the range of 1.5 nm to 1.7 nm. For the temperable coating, the discontinuous metal layer has an effective thickness in the range of 1.7 nm to 1.8 nm. The primer layer of the temperable coating is thinner than the primer layer of the non-temperable coating. | 07-09-2015 |
Patent application number | Description | Published |
20100068820 | MOLECULARLY IMPRINTED POLYMER AND USE THEREOF IN DIAGNOSTIC DEVICES - An adhesive is provided containing at least one synthetic polymer with receptor sites that enable the selective capture or release of a target molecule. A polymer is synthesized by polymerizing and cross-linking a functional monomer or functional copolymers in the presence of a target or template molecule allowing for reversible interactions between the polymer and the target molecule. The target molecule may be extracted from the polymer creating receptor sites complimentary to the target molecule. Alternatively, the target molecule may remain in the polymer network and be controllably released. The molecularly imprinted polymer is formulated into an adhesive. The adhesive can be used as a component in an in-vitro diagnostic device to release template molecules or to capture target molecules in vacated receptor sites in the synthetic polymer. | 03-18-2010 |
20110111240 | ACRYLIC BASED PRESSURE SENSITIVE ADHESIVE FORMULATION - An adhesive formulation is disclosed that includes (a) a pre-polymerized cross-linkable non-water soluble acrylic based pressure sensitive adhesive, (b) a cross-linking agent selected from the group consisting of metal chelates, silanes, epoxy-functional compounds, aziridine compounds, multifunctional amines, alkyl halide compounds, multifunctional acids, multifunctional mercaptans, multifunctional epoxy compounds, polyols in the presence of a catalyst, and combinations thereof and (c) a polyol having a weight average molecular weight in the range from 1,000 g/mol to 10,000 g/mol. When cured, the adhesive formulation is self-wetting and has a peel strength less than 20 oz/in. | 05-12-2011 |
Patent application number | Description | Published |
20130041203 | BLOOD FLOW ASSIST DEVICES, SYSTEMS AND METHODS - An implantable pump system for assisting blood flow includes a flexible conduit, at least one movable valve in fluid connection with the flexible conduit, a drive system comprising a rotary motor and a speed reducer operatively connected to the rotary motor; and a converter operatively connected to the drive system and operatively connected to the valve to drive the valve in a reciprocating linear manner. In a number of embodiments, the speed reducer includes a spur gear driving a ring gear, wherein the converter is operatively connected to the speed reducer. | 02-14-2013 |
20130041204 | CONTROL OF BLOOD FLOW ASSIST SYSTEMS - In one aspect, an implantable pump system for assisting blood flow in a patient includes a blood flow path comprising a flexible conduit, at least one valve in fluid connection with the flexible conduit, a drive system in operative connection with the valve to move the valve in a reciprocating manner, an implantable control system and at least one sensor in communicative connection with the control system. The sensor is adapted to measure at least one property of blood. The control system is adapted to control movement of the valve on the basis of data regarding position of the valve with respect to time or a derivative thereof (that is, position, velocity, acceleration or a derivative thereof) in combination with data of the measured at least one property of blood from the sensor. | 02-14-2013 |
20130041460 | BLOOD FLOW ASSIST DEVICES, SYSTEMS AND METHODS WITH ACTIVE VALVE CONTROL - An implantable pump system for assisting blood flow includes a conduit adapted to be placed in fluid connection with a blood vessel and at least one movable valve in fluid connection with the conduit. The valve includes at least one closure member in operative connection with an opening therein. The pump system further includes and an activating system adapted to actively move the closure member toward at least one of a closed position or an open position and a drive system to move the valve. The closure member can, for example, be biased toward an open position. | 02-14-2013 |
20150038772 | CONTROL OF BLOOD FLOW ASSIST SYSTEMS - A system for assisting blood flow in a patient includes an implantable pump system for assisting in blood flow from the heart and an implantable control system for communicative connection with the implantable pump system. The control system includes a pacemaker system that is operative to control heart rate and the pump system interdependently to achieve a determined level of blood flow assist. The control system is adapted to increase the heart rate of the patient to above a normal heart rate for the patient under the present conditions of the patient via the pacemaker while controlling the pump system to achieve the determined level of blood flow assist based upon the increased heart rate and a level of assist provided by the pump system. | 02-05-2015 |
Patent application number | Description | Published |
20090053183 | Treatment of Diseases and Disorders Using Self-Renewing Colony Forming Cells Cultured and Expanded In Vitro - The present invention relates to methods and uses of cells for the prevention and treatment of a wide variety of diseases and disorders and the repair and regeneration of tissues and organs using low passage and extensively passaged in vitro cultured, self-renewing, colony forming somatic cells (CF-SC). For example, adult bone marrow-derived somatic cells (ABM-SC), or compositions produced by such cells, are useful alone or in combination with other components for treating, for example, cardiovascular, neurological, integumentary, dermatological, periodontal, and immune mediated diseases, disorders, pathologies, and injuries. | 02-26-2009 |
20090087417 | METHODS FOR PROMOTING DOPAMINERGIC NEURONAL DEVELOPMENT BY USING NG4A-SUBFAMILY AND WNT-LIGANDS - Methods for promoting dopaminergic neuronal development and producing neural cells having a dopaminergic phenotype. Dopaminergic neural cells may be used for treating individuals having a neurodegenerative disease such as Parkinson's disease. Dopaminergic cells may be implanted into the brain of the individual, and/or dopaminergic neural development may be induced or enhanced in the brain of the individual. Methods comprise expressing a nuclear receptor of the NG4A subfamily, e.g. Nurr1, above basal levels within the cell and treating the cell with a Wnt ligand, thereby producing or enhancing proliferation, self-renewal, survival and/or dopaminergic induction, differentiation, survival or acquisition of a neuronal dopaminergic phenotype. The cell may be co-cultured with astrocytes or glial cells and may be contacted with an FGF growth factor. | 04-02-2009 |
20120148544 | Treatment of Diseases and Disorders Using Self-Renewing Colony Forming Cells Cultured and Expanded In Vitro - The present invention relates to methods and uses of cells for the prevention and treatment of a wide variety of diseases and disorders and the repair and regeneration of tissues and organs using low passage and extensively passaged in vitro cultured, self-renewing, colony forming somatic cells (CF-SC). For example, adult bone marrow-derived somatic cells (ABM-SC), or compositions produced by such cells, are useful alone or in combination with other components for treating, for example, cardiovascular, neurological, integumentary, dermatological, periodontal, and immune mediated diseases, disorders, pathologies, and injuries. | 06-14-2012 |
20120156192 | Treatment of Diseases and Disorders Using Self-Renewing Colony Forming Cells Cultured and Expanded In Vitro - The present invention relates to methods and uses of cells for the prevention and treatment of a wide variety of diseases and disorders and the repair and regeneration of tissues and organs using low passage and extensively passaged in vitro cultured, self-renewing, colony forming somatic cells (CF-SC). For example, adult bone marrow-derived somatic cells (ABM-SC), or compositions produced by such cells, are useful alone or in combination with other components for treating, for example, cardiovascular, neurological, integumentary, dermatological, periodontal, and immune mediated diseases, disorders, pathologies, and injuries. | 06-21-2012 |
20140073046 | Cell Populations Which Co-Express CD49C and CD90 - Substantially homogenous cells populations which co-express CD49c, CD90 and telomerase are made. In one embodiment, humans suffering from a degenerative, traumatic, acute injury, cardiac or neurological condition are treated with the substantially homogenous cells populations which co-express CD49c, CD90 and telomerase. In another embodiment, committed progenitor cells are made are made by selecting from a cultured source of a cell population which co-express CD49c and CD90 and modifying the cell population. The committed progenitor cells can be employed to treat a human suffering from a degenerative, traumatic, acute injury, cardiac or neurological condition and formulate pharmaceutical compositions. | 03-13-2014 |
20140086884 | TREATMENT OF DISEASES AND DISORDERS USING SELF-RENEWING COLONY FORMING CELLS CULTURED AND EXPANDED IN VITRO - The present invention relates to methods and uses of cells for the prevention and treatment of a wide variety of diseases and disorders and the repair and regeneration of tissues and organs using low passage and extensively passaged in vitro cultured, self-renewing, colony forming somatic cells (CF-SC). For example, adult bone marrow-derived somatic cells (ABM-SC), or compositions produced by such cells, are useful alone or in combination with other components for treating, for example, cardiovascular, neurological, integumentary, dermatological, periodontal, and immune mediated diseases, disorders, pathologies, and injuries. | 03-27-2014 |
20140099329 | TREATMENT OF DISEASES AND DISORDERS USING SELF-RENEWING COLONY FORMING CELLS CULTURED AND EXPANDED IN VITRO - The present invention relates to methods and uses of cells for the prevention and treatment of a wide variety of diseases and disorders and the repair and regeneration of tissues and organs using low passage and extensively passaged in vitro cultured, self-renewing, colony forming somatic cells (CF-SC). For example, adult bone marrow-derived somatic cells (ABM-SC), or compositions produced by such cells, are useful alone or in combination with other components for treating, for example, cardiovascular, neurological, integumentary, dermatological, periodontal, and immune mediated diseases, disorders, pathologies, and injuries. | 04-10-2014 |
Patent application number | Description | Published |
20100144018 | AUTOMATED SLIDE STAINING APPARATUS - A slide stainer assembly is disclosed. The slide stainer includes a slide carrier that is configured to carry one or more laboratory slides and a plurality of slide processing stations for processing the slides. A transport member including a plurality of engagement portions is configured for releasably engaging the slide carrier. A drive mechanism is coupled to the transport member. The drive mechanism is configured to move the transport member in a cyclical path such that, in the course of one cycle, the transport member engages a slide carrier docked in a first station, removes the slide carrier from the first station, docks the slide carrier in a second station and returns to the first station to engage another slide carrier. | 06-10-2010 |
20100170197 | METHOD AND APPARATUS FOR ATTACHING A CUTTING BLADE TO A SUBSTRATE - A method and apparatus are provided for attaching a safety cutting blade onto a substrate, such as a cardboard blank. A piece of cutting blade material is cut to length and fed to a forming station that bends the piece to form a safety cutting blade having a plurality of cutting teeth. The cutting blade is fed to a crimping station where the cutting blade is mated with a substrate and affixed with the substrate. A transport then conveys the combined cutting blade and substrate away from the crimping station. | 07-08-2010 |
20120222233 | Propane Vacuum - A vacuum cleaner having a propane fuel source, a sealed vacuum chamber and a total weight of not more than forty pounds. A vacuum cleaner system for a portable vacuum cleaner having a propane fuel source, a sealed vacuum chamber and a total weight of not more than forty pounds, and having and at least one removably attachable harness, at least one removably attachable shoulder strap, at one removably attachable set of wheels and/or at least one wheeled tray. | 09-06-2012 |
20130047367 | Propane Vacuum - A vacuum cleaner having a propane fuel source, a sealed vacuum chamber and a total weight of not more than forty pounds. A vacuum cleaner system for a portable vacuum cleaner having a propane fuel source, a sealed vacuum chamber and a total weight of not more than forty pounds, and having and at least one removably attachable harness, at least one removably attachable shoulder strap, at one removably attachable set of wheels and/or at least one wheeled tray. | 02-28-2013 |
20130061419 | PROPANE VACUUM - A vacuum cleaner having a propane fuel source, a sealed vacuum chamber and a total weight of not more than forty pounds. A vacuum cleaner system for a portable vacuum cleaner having a propane fuel source, a sealed vacuum chamber and a total weight of not more than forty pounds, and having and at least one removably attachable harness, at least one removably attachable carrier shoulder strap, at least one removably attachable handle, at least one removably attachable wheel and/or at least one rolling tray. | 03-14-2013 |
Patent application number | Description | Published |
20120174093 | SYSTEMS AND METHOD FOR DYNAMICALLY LOADING SOFTWARE PLATFORMS ONTO PLAYBACK DEVICES - Systems and methods are disclosed that dynamically load a software platform for a playback device. One embodiment includes a playback device, including a processor, and memory containing a platform installer, where the platform installer configures the processor to dynamically load a software platform from a remote server into device memory that provides a runtime environment for applications using a software platform configuration. | 07-05-2012 |
20150029087 | METHODS AND SYSTEMS FOR ADJUSTING POWER CONSUMPTION IN A USER DEVICE BASED ON BRAIN ACTIVITY - Methods and systems are disclosed herein for adjusting power consumption and/or sensitivity levels of a user device based on the current brain activity of a user. For example, a media guidance application implemented on a user device may monitor brain activity of a user. In response to determining particular brain activity (e.g., associated with the inactivity of the user), the media guidance application may initiate a stand-by mode in order to reduce power consumption. | 01-29-2015 |
20150033258 | METHODS AND SYSTEMS FOR MEDIA GUIDANCE APPLICATIONS CONFIGURED TO MONITOR BRAIN ACTIVITY - Methods and systems are disclosed herein for a media guidance application that may monitor the brain activity of a user and determine a first brain state of the user based on the brain activity, in which the first brain state corresponds to a first mood. The media guidance application may also select a second brain state that corresponds to a second mood of the user. In response to determining the first brain state does not correspond to the second brain state, the media guidance application may generate a display of a media asset to the user that is associated with inducing the second brain state. | 01-29-2015 |
20150033259 | METHODS AND SYSTEMS FOR PERFORMING OPERATIONS IN RESPONSE TO CHANGES IN BRAIN ACTIVITY OF A USER - Methods and systems are disclosed herein for performing operations in response to changes in brain activity of a user. For example, a media guidance application implemented on a user device may monitor the brain activity of the user (e.g., in order to perform one of more operations based on the brain activity of the user). In response to detecting particular brain activity (e.g., indicating that a user has fallen asleep), the media guidance application may instruct the user device to cease monitoring the brain activity of the user. | 01-29-2015 |
20150033262 | METHODS AND SYSTEMS FOR GENERATING ICONS ASSOCIATED WITH PROVIDING BRAIN STATE FEEDBACK - Methods and systems are disclosed herein for a media guidance application configured to generate for display an icon that provides feedback to a user related to the current brain activity of the user. For example, a media guidance application may monitor the brain activity of the user in order to determine whether or not to perform a particular operation. The media guidance application may further generate a display of icons that inform the user of the current brain activity of the user and/or the progress of the user towards achieving a particular operation. | 01-29-2015 |
20150033266 | METHODS AND SYSTEMS FOR MEDIA GUIDANCE APPLICATIONS CONFIGURED TO MONITOR BRAIN ACTIVITY IN DIFFERENT REGIONS OF A BRAIN - Methods and systems are disclosed herein for a media guidance application configured to monitor brain activity in various regions of a brain of a user in order to navigate, recommend, provide access to, and perform operations related to media content. For example, in response to detecting that particular brain activity in a region of the brain does not correspond to a threshold range of brain activity for that region of the brain, a media guidance application may perform a media guidance operation related to that region of the brain. | 01-29-2015 |
Patent application number | Description | Published |
20120156176 | THERMORESPONSIVE, BIODEGRADABLE, ELASTOMERIC MATERIAL AND USES THEREFOR - Provided are novel biocompatible copolymers and compositions comprising the copolymers. The copolymers are non-toxic and typically have an LCST below 37° C. Compositions comprising the copolymers can be used for wound treatment, as a cellular growth matrix or niche and for injection into cardiac tissue to repair and mechanically support damaged tissue. The copolymers comprise numerous ester linkages so that the copolymers are erodeable in situ. Degradation products of the copolymers are soluble and non-toxic. The copolymers can be amine-reactive so that they can conjugate with proteins, such as collagen. Active ingredients, such as drugs, can be incorporated into compositions comprising the copolymers. | 06-21-2012 |
20140213517 | Thermoresponsive, Biodegradable, Elastomeric Material and Uses Therefor - Provided are novel biocompatible copolymers and compositions comprising the copolymers. The copolymers are non-toxic and typically have an LCST below 37° C. Compositions comprising the copolymers can be used for wound treatment, as a cellular growth matrix or niche and for injection into cardiac tissue to repair and mechanically support damaged tissue. The copolymers comprise numerous ester linkages so that the copolymers are erodeable in situ. Degradation products of the copolymers are soluble and non-toxic. The copolymers can be amine-reactive so that they can conjugate with proteins, such as collagen. Active ingredients, such as drugs, can be incorporated into compositions comprising the copolymers. | 07-31-2014 |
20140248232 | BIODEGRADABLE, NON-THROMBOGENIC ELASTOMERIC POLYURETHANES - A method of forming an implantable article includes providing a biodegradable polymer including anti-thrombogenic groups along the length of the biodegradable polymer, biodegradable groups in the backbone of the biodegradable polymer and a plurality of functional groups adapted to react with reactive functional groups on a surface of the implantable article, and reacting at least a portion of the plurality of functional groups with the reactive functional groups on the surface of the implantable article. | 09-04-2014 |
20150132251 | Biodegradable Elastomeric Patch for Treating Cardiac or Cardiovascular Conditions - Provided herein is a biodegradable elastomeric patch that can be implanted on a heart or other portions of the cardiovascular system to repair tissue deficiencies or tissue damage. The biodegradable elastomeric patch may be engineered to have mechanical properties similar to that of soft tissue and to provide mechanical support to the damaged tissue. The biodegradable elastomeric patch also may comprise therapeutic agents to aid in the healing process. Methods also are provided for using a biodegradable elastomeric patch for treating patients suffering from tissue damage or tissue deficiencies in the cardiac or cardiovascular system. | 05-14-2015 |
20150150673 | Bioerodible Wraps and Uses There - A tubular tissue graft device is provided comprising a tubular tissue and a restrictive fiber matrix of a bioerodible polymer about a circumference of the tubular tissue. The matrix may be electrospun onto the tubular tissue. In one embodiment, the tubular tissue is from a vein, such as a saphenous vein, useful as an arterial graft, for example and without limitation, in a coronary artery bypass procedure. Also provided is method of preparing a tubular graft comprising depositing a fiber matrix of a bioerodible polymer about a perimeter of a tubular tissue to produce a tubular tissue graft device. A cardiac bypass method comprising bypassing a coronary artery with a tubular tissue graft device comprising a vein and a restrictive fiber matrix of a bioerodible polymer about a circumference of the vein also is provided. | 06-04-2015 |
20150314059 | EXTRACORPOREAL AMBULATOR ASSIST LUNG - A extracorporeal system for lung assist includes a housing, a blood flow inlet in fluid connection with the housing; a blood flow outlet in fluid connection with the housing; a plurality of hollow gas permeable fibers adapted to permit diffusion of gas between blood and an interior of the hollow gas permeable fibers, the plurality of hollow gas permeable fibers being positioned between the blood flow inlet and the blood flow outlet such that blood flows around the plurality of hollow gas permeable fibers when flowing from the blood flow inlet to the blood flow outlet; a gas inlet in fluid connection with the housing and in fluid connection with inlets of the plurality of hollow gas permeable fibers; a gas outlet in fluid connection with the housing and in fluid connection with outlets of the plurality of hollow gas permeable fibers; and at least one moving element to create velocity fields in blood flow contacting the plurality of hollow gas permeable fibers. The plurality of hollow gas permeable fibers may extend generally perpendicular to the direction of bulk flow of blood through the housing. | 11-05-2015 |
Patent application number | Description | Published |
20080268019 | Biohybrid elastomeric scaffolds and methods of use thereof - Provided herein is a biohybrid elastomeric scaffold comprising a synthetic polymeric component and a biological polymeric component. The scaffold can be fabricated to have many different forms, non-limiting examples of which include a non-woven fibrous mesh or in a porous composite. Methods of use of the biohybrid elastomeric scaffolds in wound healing and tissue regeneration are also provided. | 10-30-2008 |
20090136553 | TRIGGERABLY DISSOLVABLE HOLLOW FIBERS FOR CONTROLLED DELIVERY - Provided are tubular structures of a biocompatible, triggerably-dissolvable material such as cellulose or a copolymer having an LCST below physiological temperatures. The structures may be embedded within a cell growth scaffold. The tubular structures are useful in growing 3-dimensional tissue structures because nutrients, cytokines or other cell growth and/or differentiation compounds, as well as drugs, such as antibiotics and steroids, can be administered over time, and the tubular structures can be dissolved non-invasively. | 05-28-2009 |
20130209571 | BIOENGINEERED HUMAN CORNEAL STROMAL TISSUE - Provided herein is a method of making an aligned ECM scaffold useful in refractive correction of the eye and repair of the cornea. Methods of use of the scaffold as well as a scaffold construct are provided. | 08-15-2013 |
20130253663 | BIOHYBRID COMPOSITE SCAFFOLD - A biohybrid scaffold is provided that is useful in clinical applications for abdominal wall reconstruction, pelvic floor repair, breast reconstruction, as well as other soft tissue repairs. Methods of making and using the biohybrid scaffold are provided. | 09-26-2013 |
20130337101 | System and Method for Mandrel-Less Electrospinning - A system for electrospinning a fiber matrix on a tubular member includes at least one nozzle, a tubular member in a spaced relationship to the at least one nozzle, and a fluid source for pressurizing a lumen of the tubular member. An electrical potential is applied between the at least one nozzle and either the tubular member or fluid from the fluid source. The electrical potential draws at least one fiber from the at least one nozzle to the tubular member. | 12-19-2013 |
20140005470 | Graft Devices and Methods of Use | 01-02-2014 |
20140377213 | WET-ELECTROSPUN BIODEGRADABLE SCAFFOLD AND USES THEREFOR - A cell growth matrix is provided that comprises a biodegradable elastomeric polymer electrodeposited concurrently with a sprayed or electrosprayed liquid that is a physiological solution or which comprises a mammalian blood product such as serum, plasma or platelet rich plasma. The matrix is useful as a cell-growth matrix and for repair of a tissue in a mammal, for instance by implantation in a mammal at a site in need of repair, such as in an abdominal wall. | 12-25-2014 |
Patent application number | Description | Published |
20100158815 | Biological Cell Tracking With Ultrasound - This invention addresses the clinical problem of how to optimize biological cell based therapies, such as stem cell therapy. Currently, cell therapies administered by intravenous, intra-arterial, and/or direct tissue injection are limited by the lack of clinically available imaging methods to detect the in vivo fate of the administered cells. There are many efforts underway to develop imaging strategies for stem cells in vivo, including radionuclide and MRI-based approaches. However, these approaches are limited by potential safety issues (e.g. radioactive exposure of stem cells, toxicity of iron particles used for MRI) and difficulty in serial tracking due to complex instrumentation and/or the requirement for repetitive radiation exposure. | 06-24-2010 |
20110208113 | Directed Cell-Based Therapy Using Microbubble Tagged Cells - The disclosed technology describes compositions and methods useful for providing cell based therapy. For example, one embodiment of cell based therapy involves the regeneration of injured tissue and/or promoting wound healing. Certain embodiments provide improved therapeutic compositions using microbubbles by delivering biological progenitor cells to the injured tissues. The administration of the microbubbles is directed by acoustic radiation forces that interact with embodiments of microbubbles comprising an acoustically active gas. As such, a high efficiency of progenitor cell delivery to injured tissue is realized. One advantage of this technique over targeted delivery of pharmaceutical compounds, is that the delivered progenitors cells may be derived from the patient (i.e., personalized therapy), thereby avoiding side effects, allergic reactions, and overall problems associated with refractive drug responses. | 08-25-2011 |