Patent application number | Description | Published |
20080241244 | Preservation of bioactive materials by freeze dried foam - This invention provides methods and compositions to preserve bioactive materials in a dried foam matrix. Methods provide non-boiling foam generation and penetration of preservative agents at temperatures near the phase transition temperature of the membranes. | 10-02-2008 |
20080254132 | High pressure spray-dry of bioactive materials - This invention provides compositions and methods providing, e.g., stable powder particles containing bioactive materials. The methods include, e.g., high pressure spraying of the bioactive materials in solution or suspension, with viscosity enhancing agents and/or surfactants. Compositions of the invention provide, e.g., high initial purity, high stability in storage, and reconstitution at high concentrations. | 10-16-2008 |
20090246225 | Methods of Producing Influenza Vaccine Compositions - Methods and compositions for the optimization of production of influenza viruses suitable as influenza vaccines are provided. | 10-01-2009 |
20100184190 | Influencing viral lipid constituents - This invention provides compositions, methods and systems to modulate the lipid content and membrane characteristics of cells and virions. Growth of host cells on media containing particular amounts, classes and/or combinations of lipid supplements can influence the lipid content of the cell and viruses grown on the cell. Lipids, such as cholesterol esters, sphingomyelin, glycolipids, containing C16:0, C18:0, C18: 1n9 and/or C18:2n6 fatty acids, can influence cell permissivity for virus infection, virus yield, virus immunogenicity and/or membrane phase transition temperatures. | 07-22-2010 |
20100226939 | FORMULATIONS FOR PRESERVATION OF ROTAVIRUS - This invention provides formulations and methods for stabilizing viruses in liquid and dried formulations. In particular, formulations are provided including Zn | 09-09-2010 |
20100330162 | Spray freeze dry of compositions for pulmonary adminstration - This invention provides methods and compositions to preserve bioactive materials, such as viruses, bacteria, cells, or liposomes, in freeze dried particles suitable for pulmonary administration. Methods provide spray freeze drying of formulations to form stable freeze dried particles. | 12-30-2010 |
20100331428 | Sonic Low Pressure Spray Drying - This invention provides methods of spray drying pharmaceutical powders from a vibrating nozzle at low pressures. The method can effectively spray dry thick or viscous solutions or suspensions to provide small uniform particles. The invention includes dry particle compositions prepared by methods of low pressure spraying from vibrating nozzles. | 12-30-2010 |
20110064723 | Formulation for room temperature stabilization of a live attenuated bacterial vaccine - This invention provides methods and compositions for stabilizing proteins and vaccines in dried formulations. In particular, a cavitation method and compositions of preparing a dried vaccine are provided that stabilize the viability of live bacteria and live virus vaccines at room temperature. | 03-17-2011 |
20110243988 | Methods and Compositions for Stabilization of a Virus Vaccine - This invention provides compositions and methods for stabilizing a live attenuated virus in dried formulations. In particular, compositions and methods of preparing a dried vaccine are provided that stabilize the viability of live vaccines such as measles and adenovirus at room temperature. | 10-06-2011 |
20110243996 | Spray freeze dry of compositions for intranasal administration - This invention provides methods and compositions to preserve bioactive materials, such as peptides, nucleic acids, viruses, bacteria, cells, or liposomes, in freeze dried particles suitable for intranasal administration. Methods provide spray freeze drying of formulations to form stable freeze dried particles for intranasal administration. | 10-06-2011 |
20120009248 | Preservation of Bioactive Materials By Spray Drying - This invention provides methods and compositions to preserve bioactive materials in a matrix of powder particles. Methods provide high-pressure gas spraying and/or near supercritical spraying of formulations followed by drying in a stream of conditioned gas to form stable powder particles containing bioactive materials. | 01-12-2012 |
20120027797 | Preservation of Bioactive Materials by Freeze Dried Foam - This invention provides methods and compositions to preserve bioactive materials in a dried foam matrix. Methods provide non-boiling foam generation and penetration of preservative agents at temperatures near the phase transition temperature of the membranes. | 02-02-2012 |
20120128729 | Gallium Formulation For The Treatment And Prevention of Infectious Diseases - A method and composition for treatment of bacterial infections caused by gram negative or gram positive bacteria such as | 05-24-2012 |
20120148635 | GALLIUM FORMULATION FOR THE TREATMENT AND PREVENTION OF INFECTIOUS DISEASES - A method and composition for treatment of bacterial infections caused by gram negative or gram positive bacteria such as | 06-14-2012 |
20130189304 | PRESERVATION OF BIOACTIVE MATERIALS BY FREEZE DRIED FOAM - This invention provides methods and compositions to preserve bioactive materials in a dried foam matrix. Methods provide non-boiling foam generation and penetration of preservative agents at temperatures near the phase transition temperature of the membranes. | 07-25-2013 |
20130189305 | METHODS OF PRODUCING INFLENZA VACCINE COMPOSITIONS - Methods and compositions for the optimization of production of influenza viruses suitable as influenza vaccines are provided. | 07-25-2013 |
20130302425 | HIGHLY DISPERSIBLE POWDERS, COMPOSITIONS AND METHODS FOR PREPARATION - A method for the selection of pharmaceutically acceptable excipients that allow for the production of highly dispersible powders produced by spray drying. | 11-14-2013 |