Von Schack
David Von Schack, Arlington, MA US
Patent application number | Description | Published |
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20110136738 | Alternatively Transcribed Genes Associated with Schizophrenia - Methods of identifying gene targets associated with schizophrenia or the symptoms thereof, as well as to specific nucleic acid molecules that have been discovered to be associated with schizophrenia are provided. Accordingly, the invention also relates to methods of modulating schizophrenia or the symptoms thereof, methods of diagnosing schizophrenia or the symptoms thereof, methods for predicting the susceptibility to schizophrenia or the symptoms thereof, and methods of identifying compounds that modulate schizophrenia or the symptoms thereof via manipulations of the nucleic acid molecules and their products. | 06-09-2011 |
20110165174 | Alternatively Transcribed Genes Associated with Memory Consolidation - Methods of identifying gene targets associated with learning and memory and with memory consolidation, as well as to specific nucleic acid molecules that have been discovered to be associated with memory consolidation are provided. Accordingly, the invention also relates to methods of modulating learning and memory function, methods of diagnosing learning and memory disorders, and methods of identifying compounds that modulate learning and memory function via manipulations of the nucleic acid molecules and their products. | 07-07-2011 |
David J. Von Schack, Arlington, MA US
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20140286959 | Methods of Treating Inflammatory Disorders Using Anti-M-CSF Antibodies - The present invention relates to antibodies and antigen-binding portions thereof that specifically bind to a M-CSF, preferably human M-CSF, and that function to inhibit a M-CSF. The invention also relates to human anti-M-CSF antibodies and antigen-binding portions thereof. The invention also relates to antibodies that are chimeric, bispecific, derivatized, single chain antibodies or portions of fusion proteins. The invention also relates to isolated heavy and light chain immunoglobulins derived from human anti-M-CSF antibodies and nucleic acid molecules encoding such immunoglobulins. The present invention also relates to methods of making human anti-M-CSF antibodies, compositions comprising these antibodies and methods of using the antibodies and compositions for diagnosis and treatment. The invention also provides gene therapy methods using nucleic acid molecules encoding the heavy and/or light immunoglobulin molecules that comprise the human anti-M-CSF antibodies. The invention also relates to transgenic animals and transgenic plants comprising nucleic acid molecules of the present invention. | 09-25-2014 |
David Johannes Von Schack, Arlington, MA US
Patent application number | Description | Published |
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20090022731 | Arthritis-associated B cell gene expression - The invention features methods and compositions benefiting from differential gene expression observed in arthritis-associated B cells. | 01-22-2009 |