Tzu-Hao
Tzu-Hao Chen, Kaohsiung City TW
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20120163107 | MEMORY DEVICE CAPABLE OF OPERATION IN A BURN IN STRESS MODE, METHOD FOR PERFORMING BURN IN STRESS ON A MEMORY DEVICE, AND METHOD FOR DETECTING LEAKAGE CURRENT OF A MEMORY DEVICE - Activate one active word line of two active word lines formed between two isolation word lines to a logic-high voltage, and float another active word line of the two active word lines. Then activate a plurality of first memory cells corresponding to the active word line having the logic-high voltage to a logic “1” voltage, and write a logic “0” voltage to a plurality of second memory cells corresponding to the floating active word line. Then write the logic “1” voltage to a plurality of bit lines. Then, suspend for charge sharing for a third predetermined time. Finally, read a voltage of the floating active word line to check if any leakage path exists between the floating active word line and the active word line having the logic-high voltage. | 06-28-2012 |
Tzu-Hao Cheng, Taipei TW
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20120149754 | METHODS FOR MODULATING THE EXPRESSION AND AGGREGATION OF CAG-EXPANDED GENE PRODUCT IN CELLS AND METHODS FOR IDENTIFYING AGENTS USEFUL FOR DOING THE SAME - This invention provides a method for modulating the expression of a first gene in a cell wherein the first gene is one containing more than 36 CAG trinucleotide repeats and encoding a protein that form polyglutamine-mediated protein aggregation. Suppression of the first gene is achieved by reducing the expression of SPT4 gene or SUPT4H gene. It can also be achieved by inhibiting the formation of a Spt4/Spt5 complex or a Supt4h/Supt5h complex. Also provided is a method for identifying an agent useful for modulating the expression and aggregation of CAG-expanded gene product, or treating a polyglutamine disease such as Huntington's disease. | 06-14-2012 |
20130331437 | METHODS FOR MODULATING THE EXPRESSION AND AGGREGATION OF CAG-EXPANDED GENE PRODUCT IN CELLS AND METHODS FOR IDENTIFYING AGENTS USEFUL FOR DOING THE SAME - This invention provides a method for modulating the expression of a first gene in a cell wherein the first gene is one containing more than 36 CAG trinucleotide repeats and encoding a protein that form polyglutamine-mediated protein aggregation. Suppression of the first gene is achieved by reducing the expression of SPT4 gene or SUPT4H gene. It can also be achieved by inhibiting the formation of a Spt4/Spt5 complex or a Supt4h/Supt5h complex. Also provided is a method for identifying an agent useful for modulating the expression and aggregation of CAG-expanded gene product, or treating a polyglutamine disease such as Huntington's disease. | 12-12-2013 |
Tzu-Hao Cheng, Taipei City TW
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20130317088 | Selective Reduction of the Deleterious Activity of Extended Tri-Nucleotide Repeat Containing Genes - Aspects of the invention include methods of selectively reducing the deleterious activity of mutant extended trinucleotide repeat containing genes in a cell, as well as compositions used in such methods. The deleterious activity (e.g., toxicity and/or dis-functionality of products encoded thereby) of a mutant extended trinucleotide repeat containing gene may be selectively reduced in a variety of different ways, e.g., by selectively decreasing SPT4 mediated transcriptional activity, by enhancing functionality of proteins encoded thereby, etc. Aspects of the invention further include assays for identifying agents that find use in methods of the invention, e.g. as summarized above. Methods and compositions of the invention find use in a variety of different applications, including the prevention or treatment of disease conditions associated with the presence of genes containing mutant extended trinucleotide repeats, such as Huntington's Disease (HD). | 11-28-2013 |
Tzu-Hao Chou, New Taipei TW
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20110203256 | MOTOR - The present invention provides a motor including a combustion chamber, an oxidizer injector, a vortex generators and a nozzle. The combustion chamber can be used to dispose a solid fuel, and the oxidizer injector is used to control the flow rate of an oxidizer and to inject the oxidizer into the combustion chamber. The vortex generators is disposed on the inner wall of the combustion chamber for generating eddies to enhance the mixing of the fuel and the oxidizer. Additionally, the nozzle is connected with the combustion chamber for exhausting the gas generated by the combustion of the propellants. | 08-25-2011 |
20140352276 | Dual-Vortical-Flow Hybrid Rocket Engine - The present invention discloses a dual-vortical-flow hybrid rocket engine, including a main body and a nozzle communicating with an end of the main body. The main body includes a plurality of disk-like combustion chambers arranged longitudinally, and a central combustion chamber formed along the axial portion and communicating the disk-like combustion chambers. Each of the disk-like combustion chambers is provided with a plurality of oxidizer injection nozzles at its inner circumference surface. Inside the disk-like combustion chambers, the oxidizer is injected in nearly the tangent directions of the circumference, and the injection directions are opposite for the neighboring disk-like combustion chambers, which creates vortical flows with opposite rotating directions so as to increase the total residence time of the combustion reactions of the oxidizer and the solid-state fuel in the disk-like combustion chambers of the present invention. | 12-04-2014 |
Tzu-Hao Huang, Hsinchu County TW
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20140242794 | Methods of Patterning Small Via Pitch Dimensions - Integrated circuit methods are described. The methods include providing a photomask that includes two main features for two via openings and further includes an optical proximity correction (OPC) feature linking the two main features; forming a hard mask layer on a substrate, the hard mask layer including two trench openings; forming a patterned resist layer over the hard mask layer using the photomask, wherein the patterned resist layer includes a peanut-shaped opening with two end portion aligned with the two trench openings of the hard mask layer, respectively; and performing a first etch process to the substrate using the hard mask layer and the patterned resist layer as a combined etch mask. | 08-28-2014 |
Tzu-Hao Wang, Gueishan Township TW
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20140220025 | NOVEL STIP1 POLYPEPTIDES AND USES THEREOF - The present invention is directed toward pharmaceutical compositions comprising an isolated polypeptide and a pharmaceutically acceptable carrier. The present invention also discloses an antibody or an antigen-binding portion thereof that bind to the isolated polypeptide. Methods of inhibiting cancer cells growth are also disclosed, comprising administering the isolated polypeptide or the antibody described herein to a subject in need thereof. | 08-07-2014 |