Patent application number | Description | Published |
20100249246 | Therapeutic Compounds - A (−)-stereoisomer of formula (I): (formula I), wherein X is H or F; or a pharmaceutically acceptable salt or prodrug thereof, is useful as an anesthetic. | 09-30-2010 |
20100292346 | Stereoisomers Propofol Therapeutic Compounds - A (−)-stereoisomer of formula (I): [insert formula (I) wherein X is H or F; or a pharmaceutically acceptable salt or prodrug thereof, useful as an anesthetic. | 11-18-2010 |
20110124685 | Anesthetic Compounds - The invention provides novel phenolic ester local anesthetic compounds. The invention also provides pharmaceutical compositions that include such compounds as well as methods for making such compounds and compositions and methods for using such compounds and compositions to induce and/or maintain anesthesia and/or analgesia. | 05-26-2011 |
20110262359 | COMPOSITIONS COMPRISING ENZYME-CLEAVABLE PRODRUGS OF ACTIVE AGENTS AND INHIBITORS THEREOF - The present disclosure provides pharmaceutical compositions, and their methods of use, where the pharmaceutical compositions comprise a prodrug that provides enzymatically-controlled release of a drug and an enzyme inhibitor that interacts with the enzyme(s) that mediates the enzymatically-controlled release of the drug from the prodrug so as to attenuate enzymatic cleavage of the prodrug. The disclosure provides pharmaceutical compositions which comprise an enzyme inhibitor and a prodrug that contains an enzyme-cleavable moiety that, when cleaved, facilitates release of the drug. | 10-27-2011 |
20120196939 | Therapeutic Compounds - A (−)-stereoisomer of formula (I): (formula I), wherein X is H or F; or a pharmaceutically acceptable salt or pro drug thereof, is useful as an anesthetic. | 08-02-2012 |
20120283335 | Analogs of Propofol, Preparation Thereof and Use as Anesthetics - Compounds of formula (I) wherein X is H or F and pharmaceutically acceptable salts thereof are useful as anesthetics. | 11-08-2012 |