Patent application number | Description | Published |
20100228045 | BIOCOMPATIBLE SUSPENSION STABILIZER FOR DISPERSING INORGANIC NANOPARTICLES INTO AQUEOUS SOLUTION - The present invention relates to a suspension stabilizer for dispersing inorganic nanoparticles into aqueous medium. More particularly, the present invention is directed to a biocompatible suspension stabilizer which comprises phosphoryl domain having an affinity to the surface of an inorganic nanoparticle and poly(ethylene glycol) having an affinity to the aqueous medium, and which is prepared by reacting a biocompatible poly(ethylene glycol)-derivatized polymer with phosphine oxide having a leaving group. | 09-09-2010 |
20100247423 | GOETHITE NANOTUBE AND PROCESS FOR PREPARING THEREOF - The present invention relates to a goethite nanotube. Particularly, the present invention is directed to goethite nanotubes, which can be used as a catalyst relating to environment or a drug delivery system, and process for preparing the goethite nanotube, and process for preparing magnetite and hematite nanoparticles. | 09-30-2010 |
20110098453 | MAGNETIC NANOCOMPOSITE, AND PROCESS FOR SELECTIVE BINDING, SEPARATION AND PURIFICATION OF PROTEIN USING THE SAME - The present invention relates to a magnetic nanocomposite, a process for production thereof, a reusable protein-binding agent for separation of a protein including the magnetic nanocomposite, and a process for selective binding, separation and purification of a protein using the magnetic nanocomposite. In particular, the present invention is directed to a magnetic nanocomposite with a magnetic nanoparticle core of a magnetic nanoparticle, a silica shell coating said core, and a nanoparticle layer of a fourth period transition metal oxide, which coats said silica shell, a process for production of the magnetic nanocomposite, a reusable protein-binding agent the magnetic nanocomposite, and a process for selective binding, separation and purification of a protein using the magnetic nanocomposite. | 04-28-2011 |
20110303869 | CUBIC OR OCTAHEDRAL SHAPED FERRITE NANOPARTICLES AND METHOD FOR PREPARING THEREOF - The present invention relates to cubic or octahedral ferrite nanoparticles and a method for preparing the same. In particular, the present invention is directed to a ferrite nanocube which is superparamagnetic or ferromagnetic, and a method for preparing a ferrite nanocube, comprising heating a mixture of a metal precursor, a surfactant and a solvent. | 12-15-2011 |
20120114564 | MRI T1 CONTRASTING AGENT COMPRISING MANGANESE OXIDE NANOPARTICLE - The present invention relates to the use of and method for using MnO nanoparticles as MRI T1 contrasting agents which reduces T1 of tissue. More specifically, the present invention is directed to MRI T1 contrasting agent comprising MnO nanoparticle coated with a biocompatible material bound to a biologically active material such as a targeting agent, for example tumor marker etc., and methods for diagnosis and treatment of tumor etc. using said MRI T1 contrasting agent, thereby obtaining more detailed images than the conventional MRI T1-weighted images. The MRI T1 contrasting agent of the present invention allows a high resolution anatomic imaging by emphasizing T1 contrast images between tissues based on the difference of accumulation of the contrasting agent in tissues. Also, the MRI T1 contrasting agent of the present invention enables to visualize cellular distribution due to its high intracellular uptake. The MRI T1 contrasting agent of the present invention can be used for target-specific diagnosis and treatment of various diseases such as tumor etc. when targeting agents binding to disease-specific biomarkers are conjugated to the surface of nanoparticles. | 05-10-2012 |
20130065995 | Surface-Modified Tantalum Oxide Nanoparticles, Preparation Method Thereof, and Contrast Medium for X-Ray Computed Tomography and Highly Dielectric Thin Film Using Same - The present invention relates to a surface-modified tantalum oxide nanoparticle, a method for preparation thereof, a contrast agent (medium) for X-ray computed tomography, and a highly dielectric (high- | 03-14-2013 |
20130133484 | Method for the Mass Production of Silver Nanoparticles Having a Uniform Size - The present invention relates to a process for preparing uniform silver nanoparticles. In particular, the present invention is directed to a process for preparing silver nanoparticles comprising: (i) heating a mixture of a silver precursor and a surfactant under inert atmosphere to prepare silver nanoparticles; and (ii) separating the silver nanoparticles from the reaction products of the step (i). | 05-30-2013 |
20130272965 | Biocompatible Agent for Dispersing Nanoparticles into an Aqueous Medium Using Mussel Adhesive Protein-Mimetic Polymer - Provided are a mussel adhesive protein-mimetic dispersion stabilizing agent to disperse nanoparticles in an aqueous medium, a colloidal solution including nanoparticles dispersed and stabilized by the dispersion stabilizing agent, and a contrast agent including the colloidal solution. More particularly, the mussel adhesive protein-mimetic dispersion stabilizer is a polyethyleneimine-graft-(poly-ethyleneglycol;polyDOPA) PEI-graft-(PEG;PDOPA). The graft polymer is formed of two parts. One is polyethyleneglycol grafted with a polyethyleneime which has an affinity to an aqueous medium, and the other is polyDOPA which has an affinity to the surface of nanoparticles. Because of those characteristics, the stabilizer shows a stable dispersion of nano particles in the aqueous medium. | 10-17-2013 |
20130323182 | METHOD OF PREPARING IRON OXIDE NANOPARTICLES COATED WITH HYDROPHILIC MATERIAL, AND MAGNETIC RESONANCE IMAGING CONTRAST AGENT USING THE SAME - The present invention relates to a method of preparing biocompatible iron oxide nanoparticles by coating iron oxide nanoparticles having improved magnetism via annealing treatment using salt particles with a hydrophilic material and to a magnetic resonance imaging (MRI) contrast agent including the iron oxide nanoparticles prepared thereby. Among hydrophilic materials, carboxymethyl dextran (CM-dextran) is the most efficient in terms of stabilizing the annealed iron oxide nanoparticles and exhibiting contrast effects. | 12-05-2013 |
20140023594 | MRI CONTRAST AGENT FOR LYMPHOGRAPHY BASED ON IRON OXIDE NANOPARTICLES AND METHOD FOR IMAGING LYMPH NODE USING THE SAME - Provided are a contrast agent for contrast imaging lymph node, which includes iron oxide nanoparticles dispersed and stabilized in an aqueous medium by a mussel adhesive protein-mimetic copolymer, a method for contrast enhanced lymphography using the foregoing contrast agent, and a method for diagnosis of lymph node cancers using the foregoing contrast agent. Using such a mussel adhesive protein-mimetic copolymer, the surface of iron oxide is modified and dispersed well in water to prepare a colloidal solution, which in turn forms the contrast agent containing the colloidal solution. The inventive contrast agent does not have toxicity and is easily taken up to the lymph node to exhibit excellent contrast imaging effects. The contrast agent of the present invention is useful for diagnosis of metastatic cancers. | 01-23-2014 |
20150079162 | CERIA NANOCOMPLEX, PHARMACEUTICAL COMPOSITION COMPRISING SAID CERIA NANOCOMPLEX, AND METHOD FOR PREPARING SAME - The present invention relates to ceria nanocomposite, pharmaceutical composition comprising the ceria nanocomposite, and method for preparing same. More particularly, the present invention is directed to a ceria nanocomposite comprising a ceria nanoparticle, wherein the ceria nanoparticle is encapsulated with a surfactant and the surfactant is encapsulated with polyethylene glycol-phospholipid, pharmaceutical composition for preventing or treating ischemic stroke comprising thereof and method for preparing the same. | 03-19-2015 |