Stapels
Christopher Stapels, Mills, MA US
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20150285921 | POSITION SENSITIVE SOLID-STATE PHOTOMULTIPLIERS, SYSTEMS AND METHODS - An integrated silicon solid state photomultiplier (SSPM) device includes a pixel unit including an array of more than 2×2 p-n photodiodes on a common substrate, a signal division network electrically connected to each photodiode, where the signal division network includes four output connections, a signal output measurement unit, a processing unit configured to identify the photodiode generating a signal or a center of mass of photodiodes generating a signal, and a global receiving unit. | 10-08-2015 |
Martha Stapels, Bellingham, MA US
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20150087073 | METHODS FOR QUANTIFYING POLYPEPTIDES USING MASS SPECTROMETRY - A method for identifying a polypeptide a specimen can include (i) treating a specimen suspected of comprising an insulin with a base; (ii) extracting a first fraction of the treated specimen by solid phase extraction using a mixed mode or polymeric reversed-phase media and a first solvent comprising an acid; (iii) separating a component of the first fraction by liquid chromatography using a chromatographic surface including a hydrophobic surface group and one or more ionizable modifiers, and a second solvent comprising an acid; and (iv) analyzing the component of the first fraction by mass spectroscopy, thereby identifying the polypeptide, if present, using a signal corresponding to a sequence fragment ion from the polypeptide. The signal can correspond to an intact multiply charged precursor fragment selected in a first quadrupole and its corresponding sequence fragment ion selected in a final quadrupole. | 03-26-2015 |
Martha Degen Stapels, Millis, MA US
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20110226941 | Techniques For Performing Retention-Time Matching Of Precursor And Product Ions And For Constructing Precursor And Product Ion Spectra - Techniques are described for matching a precursor ion with one or more related product ions, including providing a plurality of input data sets obtained from a plurality of injections, each of the plurality of input data sets including a same precursor ion and one or more product ions, normalizing the plurality of input data sets in accordance with a single retention time for the precursor ion, for each of the plurality of input data sets, determining which product ions are within a predetermined retention time window with respect to the single retention time for the precursor ion, and if a product ion is within the predetermined retention time window in at least one of the plurality of input data sets, determining that the product ion is related to the precursor ion having the single retention time | 09-22-2011 |
20120171773 | Temperature Control Of Enrichment And Separation Columns In Chromatography - A method of analyzing samples includes loading a sufficient quantity of the sample onto a trap column to overload the trap column; heating an analytical column and the trap column to a greater temperature than the analytical column; and pumping a solvent, to the trap column, having a solvent composition profile that, in cooperation with a temperature differential, causes at least some of the components to elute sequentially from the trap column to the analytical column and focus on the analytical column prior to eluting from the analytical column; or optionally: loading a small-molecule sample onto a cooled portion of an analytical column; heating the analytical column; and pumping a solvent, to the heated analytical column, to elute the components from the analytical column. Chromatographic separation includes: a trap column; a separation column; a trap-column heater; a separation-column heater; a solvent pump unit; and a control unit can be used. | 07-05-2012 |
Michael Stapels, Kleve DE
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20130239985 | CLEANSING COMPOSITION - A cleansing composition containing the following components (A) and (B): (A) an ether carboxylate of Formula (1) R | 09-19-2013 |
Rob Stapels, Janiksenlinna FI
Patent application number | Description | Published |
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20100071480 | Load Measuring Device, Manufacturing Method for the Device and Control Method Using the Device - A load measuring device for measuring a load acting on an elastically deformable member, has a distance sensor for measuring a length change in response to a deformation of the deformable member under a load. The sensor has a sensing element and a reference element arranged such that a portion of the elastically deformable member is interposed between the sensing element and the reference element. For paper manufacturing or finishing, two members between which the load is measured are cooperating rolls, at least one of which is provided with an elastic cover. One of the rolls includes the sensing element and the other roll includes the reference element. Alternatively, the two members are a roll and a cooperating belt, one having an elastic cover. Also, the sensing element and the reference element may be formed in one and the same member. | 03-25-2010 |