Stanley, GB
Christopher J. Stanley, Cambridgeshire GB
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20120009595 | BINDING OF AGGREGATED FORMS OF PROTEINS - Aggregating proteins such as IgG, are bound selectively in the presence of the non-aggregated protein using a polyionic binding agent such as dextran sulphate or pentosan (anionic), or polyamine compounds such as pDADMAC (cationic) under selective binding conditions including the use of n-lauroylsarcosine at mildly alkaline pH, and may then be assayed. | 01-12-2012 |
Christopher J. Stanley, Huntingdon GB
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20100184054 | BINDING OF PATHOLOGICAL FORMS OF PRION PROTEINS - A process for the selective binding of an aggregating abnormal form of a protein in the presence of the nonaggregating normal form of the protein, including contacting under selective binding conditions a material containing both the abnormal and normal forms with a binding agent which is a polyionic material having a binding avidity for the aggregating form of the protein as present in the sample. | 07-22-2010 |
Christopher John Stanley, London GB
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20100035859 | TREATMENT OF PROTEIN AGGREGATION DISEASES - A method of treatment for the prevention or therapy of a protein aggregation disease includes the administration in combination of a first active medicament and a second active medicament, wherein the first active medicament is active to impede aggregation of amyloid protein and the second active medicament is active to disaggregate previously formed aggregates of amyloid protein. | 02-11-2010 |
20100143883 | CAPTURE OF MYCOBACTERIA LIKE MICRO-ORGANISMS - A method for the capture from a sample of micro-organisms having a hydrophobic surface, which method includes contacting the micro-organisms with a capture reagent, which capture reagent has both a hydrophobic character whereby the capture reagent binds the micro-organisms by hydrophobic interaction therewith and a polar character, the capture reagent either being present on a surface and capturing the micro-organisms thereto, or being present in solution, the method then further including capturing the micro-organisms to a surface by binding the capture reagent to the surface by polar interaction between the surface and the capture reagent. | 06-10-2010 |
Christopher John Stanley, Cambridge GB
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20100291564 | Methods for Detection of Micro-Organisms - NAD-dependent ligase is identified as an indicator of micro-organisms in a sample. A method of detecting the presence of an NAD-dependent ligase expressing micro-organism in a sample comprises the steps of: (a) contacting the sample with a nucleic acid molecule which acts as a substrate for NAD-dependent ligase activity in the sample, (b) incubating the thus contacted sample under conditions suitable for NAD-dependent ligase activity; and (c) specifically determining the presence of a ligated nucleic acid molecule resulting from the action of the NAD-dependent ligase on the substrate nucleic acid molecule to indicate the presence of the NAD-dependent ligase expressing micro-organism. The method has a number of applications and kits for carrying out the methods are also provided. Lysostaphin preparations substantially free from nuclease and/or ligase contaminants are produced by heating a lysostaphin preparation which contains nuclease and/or ligase contaminants under conditions whereby nuclease and/or ligase activity is reduced whereas endopeptidase activity of the lysostaphin is substantially unaffected. | 11-18-2010 |
20130171689 | CAPTURE OF MICRO-ORGANISMS - Micro-organisms, including fungi, viruses and bacteria such as | 07-04-2013 |
Colin Stanley, Glasgow GB
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20100218819 | SEMICONDUCTOR OPTOELECTRONIC DEVICES AND METHODS FOR MAKING SEMICONDUCTOR OPTOELECTRONIC DEVICES - A semiconductor-based optoelectronic device such as a solar cell has an n-type layer and a p-type layer, together forming a p-n junction. Contact regions are formed on the device, with light-receiving regions between contact regions. A window layer is formed over the n-type layer or the p-type layer at the light-receiving region, the window layer promoting reduced carrier recombination at the surface of the n-type or p-type layer, and/or reflection of minority carriers in the n-type or p-type layer towards the p-n junction. The device has a window protection layer formed over the window layer, the window protection layer providing protection from degradation of the window layer during manufacture and/or operation of the device. For GaAs-based devices the window layer may be Al0.9Ga0.1As and the window protection layer may be GaAs. Additionally, an AlAs etch stop layer may be provided over the window protection layer. | 09-02-2010 |
Colin Roy Stanley, Glasglow GB
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20090206319 | SEMICONDUCTOR DEVICE FOR GENERATING AN OSCILLATING VOLTAGE - A semiconductor device which displays an oscillating voltage due to the creation of charge domains which includes a plurality of semiconductor layers and at least two electrodes spaced from one another in the direction of the layers, an upper of which has a composition and/or dimensions predetermined so that a charge therein balances a depletion from a surface charge of the upper layer on application of a potential difference across said electrodes. The electrodes may be in contact solely with the upper layer. A method of manufacturing the device is also provided. | 08-20-2009 |
Emily Stanley, West Sussex GB
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20100105660 | ORGANIC COMPOUNDS75074 - A compound of formula (I), or tautomers, or stereoisomers, or solvates, or pharmaceutically acceptable salts thereof, wherein M | 04-29-2010 |
20110152261 | Organic compounds - There are described cyclohexyl amide derivatives useful as corticotropin releasing (CRF | 06-23-2011 |
Emily Stanley, Horsham GB
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20100035898 | Organic compounds - There are described cyclohexyl amide derivatives useful as corticotropin releasing factor (CRF | 02-11-2010 |
20140088105 | Cyclohexyl Amide Derivatives and Their Use as CRF-1 Receptor Antagonists - There are described cyclohexyl amide derivatives useful as corticotropin releasing factor (CRF | 03-27-2014 |
20140171403 | Autotaxin inhibitors - The present invention relates to novel compounds that are autotaxin inhibitors, processes for their preparation, pharmaceutical compositions and medicaments containing them and to their use in diseases and disorders mediated by autotaxin. | 06-19-2014 |
20140171404 | Autotaxin inhibitors - The present invention relates to novel compounds that are autotaxin inhibitors, processes for their preparation, pharmaceutical compositions and medicaments containing them and to their use in the treatment of an ATX-dependent or ATX-mediated disease or condition. | 06-19-2014 |
Felix Stanley, Derby GB
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20140192049 | MEDIAL SURFACE GENERATION - A method of generating a medial mesh of an object. The method first includes obtaining a surface mesh of the object. Define a set of node normal vectors, each having its origin at a node and being directed towards the interior of the object. For each node: select a node normal from the set having their origins at that node; define a sphere wherein a surface of the sphere includes the node and the centre point is positioned at a scalar multiple of the node normal; increment the centre point along the scalar multiple; iterate until the surface of the sphere includes another node or element. The centre point is recorded as a medial point and the diameter as a thickness. The medial mesh is generated from the set of medial points and object thicknesses. | 07-10-2014 |
Giles Stanley, Chandlers Ford GB
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20080262562 | Energy Harvester for an Implant Device - This invention relates to the use of an electromagnetic generator and a pressure bladder located within a biological body in such a position to take advantage of the pressure fluctuations found within that body to produce electrical power. The invention uses these pressure fluctuations to displace the moving parts of a generator, to produce electricity in accordance with the Faraday principal, to power implanted devices. | 10-23-2008 |
Jeremy James Stanley, Basildon GB
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20130140013 | RADIATOR FIN - A radiator fin ( | 06-06-2013 |
20130160479 | SOUND-ATTENUATING HOUSING - Sound-attenuating housing ( | 06-27-2013 |
John Christopher Stanley, Cambridgeshire GB
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20090098539 | Methods and Kits for Detecting an Enzyme Capable of Modifying a Nucleic Acid - An improved method of detecting an enzyme in a sample, which enzyme is capable of adding or removing a chemical moiety to or from a nucleic acid molecule, thereby conferring the nucleic acid molecule with the ability to be extended to generate a novel detectable nucleic acid molecule, comprises the steps of allowing the sample to be tested for the presence of the enzyme to interact with the nucleic acid molecule; and testing for interaction of the enzyme with the nucleic acid molecule by detecting the novel nucleic acid molecule generated only in the presence of the enzyme. The preferred enzyme is a phosphatase. The methods have a number of applications, for example in enhancing the sensitivity of immunoassays, for detecting pathogen associated phosphatase, for diagnosing certain conditions and for detecting specific contaminants in a sample. | 04-16-2009 |
John K. Stanley, Lancashire GB
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20080255600 | Endoscopic Dissector - A dissection device comprising an elongate cannula having proximal and distal ends and a central axis and arranged to receive at least a remote viewing device therein, a handle arranged to be attached to the proximal end of the elongate cannula and a dissection tip arranged to be attached to the distal end of the elongate cannula, the dissection tip comprising a curved hollow shroud that when the dissection tip is orientated for use defines a substantially concave working cavity having an open underside, the hollow shroud comprising a pair of laterally extending lateral extensions, each wing extending from an opposing lateral portion of the periphery of the hollow shroud. | 10-16-2008 |
Martin Stanley, Grantham GB
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20140346308 | SYSTEM FOR STRENGTHENING POLES - Disclosed is a system for strengthening a pole comprising a support element for supporting the pole; and fastening means for securing the support element to the pole; wherein the fastening means comprises a pair of mutually engaging fastening parts, including a bolt part and a corresponding nut part adapted to engage with the bolt part; and wherein the support element comprises an aperture adapted to receive a first one of the pair of fastening parts, and wherein at least one of the aperture and the first fastening part is shaped to prevent rotation of the first fastening part when located in the aperture. | 11-27-2014 |
Martin Luke Stanley, Newcastle Upon Tyne GB
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20140283125 | FACIAL RECOGNITION-BASED INFORMATION DISCOVERY - A system and method thereof for control, by a user, regarding information made publicly available about the user to authorized services and/or applications based on an image of the face of the user. A system and method thereof for obtaining user-related information based on facial recognition. | 09-18-2014 |
Maurice Stanley, Worcestershire GB
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20090287452 | Method and Apparatus for Accurate Footwear and Garment Fitting - The invention relates to an improved method of providing customers with indications of whether certain articles, for instance footwear or clothing, will fit that customer and to making recommendations for articles that will fit. The method takes body size data regarding the size/shape of the appropriate body part of the customer and compares the data against a reference body size/shape associated with an article. The reference body size is obtained from the recorded body sizes of previous customers who are known to fit the particular article. A match between the current customer's body size and the reference body size for an article is an indication that such article will fit that customer. The present invention thus avoids any need to obtain any size information about the article itself and can generate the reference body size data through normal retail practices. The invention is particularly applicable to the fitting of shoes. | 11-19-2009 |
20120236288 | Range Based Sensing - Ranging apparatus capable of projecting patterns of structured light tailored for use at particular ranges or depth regimes. Detected light points in a scene can be compared to pre-determined pattern templates to provide a simple and low cost gesture recognition system, for example as an interface to a smartphone or PDA. A structured light generator can be adapted to switch back and forth between said first and second structured patterns, either automatically according to a timing control, or adaptively in response to sensed information from the illuminated scene. Alternatively the structured light generator can be adapted to project the first and second patterns simultaneously. Separate light generators may be employed for the different patterns, or alternatively components can be shared. | 09-20-2012 |
Maurice Stanley, Malvern GB
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20080204853 | SPATIAL LIGHT MODULATOR - A spatial light modulator system includes an optically addressable spatial light modulator (OASLM) and an electrical addressable spatial light modulator (EASLM) arranged to transmit light onto the OASLM. A first controller is configured to address the EASLM with both a positive image and a negative image. A second controller is configured to apply a first bipolar voltage pulse to the OASLM associated with reception of the positive image and apply a second bipolar voltage pulse to the OASLM associated with reception of the negative image. | 08-28-2008 |
20080211836 | DRIVE SYSTEM FOR AN OPTICALLY ADDRESSED SPATIAL LIGHT MODULATOR - A system includes a driving apparatus configured to operate on an optically addressed spatial light modulator (OASLM) including a modulation layer notionally divided into a plurality of separately addressable segments. A pulse generator is configured to provide one or more voltage patterns and an optical pattern generator configured to provide one or more optical patterns of light. For each segment of the OASLM, the driving apparatus is further configured to write, over a predetermined number of write operations, a predetermined amount of light associated with the one or more optical patterns. The driving apparatus is configured to apply a reset pulse associated with the one or more voltage patterns, such that a resulting net charge on the modulation layer is zero. | 09-04-2008 |
20080278780 | HOLOGRAPHIC IMAGING SYSTEMS - A holographic imaging system includes an electrical addressable spatial light modulator (EASLM) and an optically addressable spatial light modulator (OASLM). A read light is configured to illuminate the OASLM, and a controller is configured to address the EASLM with both positive and negative sub-images and transmit the positive and negative sub-images to the OASLM. The controller is further configured to address the OASLM with an operating voltage, wherein the read light generates a holographic image comprised of diffraction patterns from the positive and negative sub-images. | 11-13-2008 |
20120069412 | HOLOGRAPHIC IMAGING SYSTEMS - A holographic imaging system includes an electrical addressable spatial light modulator (EASLM) and an optically addressable spatial light modulator (OASLM). A read light is configured to illuminate the OASLM, and a controller is configured to address the EASLM with both positive and negative sub-images and transmit the positive and negative sub-images to the OASLM. The controller is further configured to address the OASLM with an operating voltage, wherein the read light generates a holographic image comprised of diffraction patterns from the positive and negative sub-images. | 03-22-2012 |
20120300489 | Light Generator - A structured light generator for illuminating a scene comprising a light source and a light guide comprising a tube having a longitudinal axis and having substantially reflective sides arranged to project an array of distinct images of the light source towards the scene in the manner of a kaleidoscope, wherein including a light deflection element to redirect light so that the projection axis and the light guide axis are angled with respect to one another. In this way the light guide, which is typically an elongate structure, can be ‘folded’ away from the direction of light projection, which offers advantages in terms of packaging of the light generator where thickness in the direction of projection is desirably minimised. | 11-29-2012 |
Paul Stanley, Edinburgh GB
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20090326353 | PROCESSING AND DETECTING BASELINE CHANGES IN SIGNALS - According to embodiments, systems and methods for detecting the occurrence of events from a signal are provided. A signal processing system may analyze baseline changes and changes in signal characteristics to detect events from a signal. The system may also detect events by analyzing energy parameters and artifacts in a scalogram of the signal. Further, the system may detect events by analyzing both the signal and its corresponding scalogram. | 12-31-2009 |
Russell Stanley, Basingstoke GB
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20130120570 | METHOD, APPARATUS AND SYSTEM FOR PRIORITISING CONTENT FOR DISTRIBUTION - A method of prioritising content for distribution from a camera to a server over an Internet Protocol (IP) network, the method comprising: storing a plurality of audio and/or video data packages to be distributed to the server over the IP network; obtaining information indicating the priority at which each audio and/or video package is to be distributed over the IP network, the priority being determined in accordance with the content of the audio and/or video package; and sending each audio and/or video data package over the IP network, the order in which each audio and/or video data package is sent being determined in accordance with the indicated priority. | 05-16-2013 |
Steven Stanley, Risley GB
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20110017924 | NOVEL RADIATION DETECTOR - The invention provides a device for the detection and mapping of radiation, the device comprising a polymeric core located within an external shell material, wherein the polymeric core comprises at least one radiation sensitive component and the external sheath comprises a collimation sheath. Preferably, the polymeric core comprises a spherical core which is encased within the external shell. The external shell is preferably comprised of a metal, most preferably lead or tungsten. The invention also provides a method for the detection and mapping of radiation in a location, which comprises: (a) placing a device according to the invention in the location to be investigated; (b) allowing the device to remain in the location and be exposed to the radiation for a predetermined length of time; (c) removing the device from the location; (d) removing the polymeric core from the external shell; and (e) analysing said polymeric core by means of an optical analysis technique applying a software-based image reconstruction algorithm in order to determine the location, form and intensity of said radiation. The device and method of the invention facilitate the detection and mapping of radiation, and find particular use in mapping the location, intensity and identity of radio-logical hazards in 3 dimensions in sites such as active cells, gloveboxes, other active plants and confined spaces. Advantages over the prior art include the lack of requirement for an electrical supply, and the ability to deal with high radiation backgrounds and to be deployed in confined or restricted spaces. | 01-27-2011 |
Steven Anthony Stanley, Chester GB
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20140174912 | APPLICATION OF COATING MATERIALS - The invention relates to apparatus and a method for applying coatings to substrates such as, for example, a lens or electronic component. The apparatus includes a coating chamber in which there is provided one or more magnetrons which include, typically, an at least partially oxidised metal or metal alloy. A carrier is provided for the substrates to be moved and held in the coating chamber and the carrier is formed from a plurality of units on which the substrates are positioned and the units can be brought together to form the carrier. | 06-26-2014 |
Steven John Stanley, Lancashire GB
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20130234033 | NOVEL RADIATION DETECTOR - The invention provides a device for the detection and mapping of radiation, the device comprising a polymeric core ( | 09-12-2013 |
Steven John Stanley, Warrington Cheshire GB
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20120138806 | NOVEL RADIATION DETECTOR - The invention provides a device for the detection of elevated levels of radiation in remote locations, the device comprising a scintillator crystal and a variable length fibre optic cable. Preferably, the scintillator comprises an inorganic scintillator and the fibre optic cable comprises a metal coated fibre optic cable. The device preferably also comprises a light measurement device which co-operates with recording means such that the radiation levels of the environment in which the device is deployed may be determined. The device has potential widespread application in the nuclear industry, for the monitoring of products, processes and/or facilities that exhibit very high levels of radiation. | 06-07-2012 |
Timothy Stanley, Hertfordshire GB
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20130237579 | STABLE PHARMACEUTICAL COMPOSITIONS COMPRISING ONE OR MORE HMG-COA REDUCTAS INHIBITIORS - The present invention relates to stable pharmaceutical compositions comprising one or more HMG-CoA reductase inhibitors, processes for preparing the stable compositions and uses for the compositions. The stable pharmaceutical compositions of the invention may be used, in particular, for the treatment of hyperlipoproteinemia and atherosclerosis. | 09-12-2013 |
Warren Roy Stanley, Hattfield GB
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20140028998 | Fluid-Borne Particle Detector - There is disclosed improved apparatus and methods for detection of shape, size and intrinsic fluorescence properties of a fluid borne particle wherein the apparatus comprises a laser, two light sources, two detectors, and optionally a third detector. The apparatus is particularly suitable for detection of airborne biological particles. | 01-30-2014 |
Warren Roy Stanley, Herts GB
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20100328665 | FLUID-BORNE PARTICLE DETECTOR - There is disclosed improved apparatus and methods for detection of shape, size and intrinsic fluorescence properties of a fluid borne particle wherein the apparatus comprises a laser, two light sources, two detectors, and optionally a third detector. The apparatus is particularly suitable for detection of airbone biological particles. | 12-30-2010 |