Srinivasan, Mountain View
Maithreyan Srinivasan, Mountain View, CA US
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20090053724 | System and method for adaptive reagent control in nucleic acid sequencing - An embodiment of a method for adaptive reagent control is described that comprising a) introducing a first concentration of an enzyme reagent into a reaction environment with a reaction substrate, where the enzyme reagent and reaction substrate are constituent parts of a sequencing process; b) measuring a level of activity of the first concentration of the enzyme reagent in the reaction environment, where the level of activity comprises a measurable product of a reaction between the enzyme reagent and the reaction substrate; c) identifying an optimal concentration using the measured level of activity of the first concentration; and d) performing the sequencing process in the reaction environment using the optimal concentration of the enzyme reagent, where the sequencing process comprises an iterative series of sequencing reactions. | 02-26-2009 |
20090105959 | System and method for identification of individual samples from a multiplex mixture - An embodiment of an identifier element for identifying an origin of a template nucleic acid molecule is described that comprises a nucleic acid element comprising a sequence composition that enables detection of an introduced error in sequence data generated from the nucleic acid element and correction of the introduced error, where the nucleic acid element is constructed to couple with the end of a template nucleic acid molecule and identifies an origin of the template nucleic acid molecule. | 04-23-2009 |
20100267043 | System and method for identification of individual samples from a multiplex mixture - An embodiment of an identifier element for identifying an origin of a template nucleic acid molecule is described that comprises a nucleic acid element comprising a sequence composition that enables detection of an introduced error in sequence data generated from the nucleic acid element and correction of the introduced error, where the nucleic acid element is constructed to couple with the end of a template nucleic acid molecule and identifies an origin of the template nucleic acid molecule. | 10-21-2010 |
Mathreyan Srinivasan, Mountain View, CA US
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20100222232 | ENRICHMENT AND SEQUENCE ANALYSIS OF GENOMIC REGIONS - The present invention provides novel methods for reducing the complexity of preferably a genomic sample for further analysis such as direct DNA sequencing, resequencing or SNP calling. The methods use pre-selected immobilized oligonucleotide probes to capture target nucleic acid molecules from a sample containing denatured, fragmented (genomic) nucleic acids for reducing the genetic complexity of the original population of nucleic acid molecules. | 09-02-2010 |
Mukund Srinivasan, Mountain View, CA US
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20100278191 | Hierarchical Rate Limiting of Control Packets - Line cards receive control packets and perform a hierarchical rate limiting on those control packets. A set of identifier keys are extracted from the control packets and the protocol of those control packets are determined. At a first level, the control packets are rate limited per unique set of identifier keys per protocol. Those packets which fail the first rate limiting level are dropped. Those packets which pass the first rate limiting level are rate limited at a second level per protocol type. Those packets which fail the second level rate limiting are dropped while those packets which pass the second level rate limiting are sent to the control card for further processing. | 11-04-2010 |
20120195323 | HIERARCHICAL RATE LIMITING OF CONTROL PACKETS - Line cards receive control packets and perform a hierarchical rate limiting on those control packets. A set of identifier keys are extracted from the control packets and the protocol of those control packets are determined. At a first level, the control packets are rate limited per unique set of identifier keys per protocol. Those packets which fail the first rate limiting level are dropped. Those packets which pass the first rate limiting level are rate limited at a second level per protocol type. Those packets which fail the second level rate limiting are dropped while those packets which pass the second level rate limiting are sent to the control card for further processing. | 08-02-2012 |
Ravi Srinivasan, Mountain View, CA US
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20090137926 | Apparatus and Methods for Repetitive Microjet Drug Delivery - An active, transdermal delivery system includes a support structure and a fluid reservoir within the support structure configured to contain a fluid to be delivered transdermally. There is also at least one exit orifice defined in the support structure that is in communication with the fluid reservoir. The orifice has a diameter of between about 1 μm and 500 μm. Furthermore, a repeatable activation means is disposed within the support structure and is in cooperation with the exit orifice for ejection of fluid in response to an activation signal. | 05-28-2009 |
Seshadri Srinivasan, Mountain View, CA US
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20090069675 | Adaptive motion imaging in medical diagnostic ultrasound imaging - Motion imaging in medical diagnostic ultrasound is adaptive. Clutter or threshold processing adapts as a function of data for different locations or for different times. Spatial filtering adapts as a function of data at different spatial locations at a same time. The steering angle may be set as a function of region based on the vessel orientation and maximum velocity. The region of interest for motion imaging may be expanded to counteract, at least in part, a shift due to the steering angle. | 03-12-2009 |
20100022884 | SPECTRAL DOPPLER WITH MULTIPLE SPATIALLY DISTINCT GATES - Spatially distinct Spectral Doppler information is displayed. A spectrum is determined for each of a plurality of spatial locations, such as associated with different receive beams. Given a plurality of spectra at different spatial locations, an image may be generated as a function of the spectra. For example, a two-dimensional image has display values for different pixels or locations derived from one or more characteristics of the spectra, such as the maximum velocity with energy above a threshold for each location. As another example, the spectrum from the set of spectra with the highest maximum velocity is selected for generating a spectral strip display. | 01-28-2010 |