Patent application number | Description | Published |
20090117549 | Aptamer-based methods for identifying cellular biomarkers - In this invention, a biomarker discovery method has been developed using specific biotin-labeled oligonucleotide ligands and magnetic streptavidin beads. In one embodiment, the oligonucleotide ligands are firstly generated by whole-cell based SELEX technique. Such ligands can recognize target cells with high affinity and specificity and can distinguish cells that are closely related to target cells even in patient samples. The targets of these oligonucleotide ligands are significant biomarkers for certain cells. These important biomarkers can be captured by forming complexes with biotin-labeled oligonucleotide ligands and collecting the complexes using magnetic streptavidin beads, whereupon the captured biomarkers are analyzed to identify the biomarkers. Analysis of biomarkers include HPLC-Mass Spectroscopy analysis, polyacrylamide gel electrophoresis, flow cytometry, and the like. The identified biomarkers can be used for pathological diagnosis and therapeutic applications. Using the disclosed methods, highly specific biomarkers of any kinds of cells, in particular cancer cells, can easily be identified without prior knowledge of the existence of such biomarkers. | 05-07-2009 |
20090130650 | Methods for the production of highly sensitive and specific cell surface probes - A system and method for producing an oligonucleotide having a high affinity for extracellular or cell surface markers on a target cell. The resultant oligonucleotide probe can be used to detect a target biomolecule, in particular a cancer cell or infectious agent such as a bacterium, virus, or fungus, comprising an aptamer having a high affinity for the biomolecule, wherein at least one labeled dye is attached to the aptamer. The labeled dye causes the aptamer to emit a baseline, non-visible emission. When the aptamer (also referred to herein as a probe) of the invention interacts with a target biomolecule, the fluorescence emission changes from the baseline emission to an emission that is visually detectable. | 05-21-2009 |
20110124015 | APTAMER-BASED METHODS FOR IDENTIFYING CELLULAR BIOMARKERS - In this invention, a biomarker discovery method has been developed using specific biotin-labeled oligonucleotide ligands and magnetic streptavidin beads. In one embodiment, the oligonucleotide ligands are firstly generated by whole-cell based SELEX technique. Such ligands can recognize target cells with high affinity and specificity and can distinguish cells that are closely related to target cells even in patient samples. The targets of these oligonucleotide ligands are significant biomarkers for certain cells. These important biomarkers can be captured by forming complexes with biotin-labeled oligonucleotide ligands and collecting the complexes using magnetic streptavidin beads, whereupon the captured biomarkers are analyzed to identify the biomarkers. Analysis of biomarkers include HPLC-Mass Spectroscopy analysis, polyacrylamide gel electrophoresis, flow cytometry, and the like. The identified biomarkers can be used for pathological diagnosis and therapeutic applications. Using the disclosed methods, highly specific biomarkers of any kinds of cells, in particular cancer cells, can easily be identified without prior knowledge of the existence of such biomarkers. | 05-26-2011 |
Patent application number | Description | Published |
20110037886 | Wafer level camera module with molded housing and method of manufacturing - A disclosed method of manufacturing a camera module includes providing an optical assembly, providing an integrated circuit image capture device (ICD), fixing the optical assembly directly to the ICD, then forming a housing directly over the optical assembly. The method further includes forming the housing over the ICD and the optical assembly via transfer molding. The method further includes forming solder balls on the rear surface of the ICD so as to enable the camera module to be reflow soldered to a host device. In an alternative embodiment of the present invention, the method includes providing a second ICD, providing a second optical assembly, providing a housing substrate, fixing the first optical assembly over the first ICD, fixing the second optical assembly over the second ICD, and forming the housing substrate over both the first and second optical assemblies. The alternative method further includes separating the housing substrate in to a first portion formed over the first optical assembly and second portion formed over the second optical assembly, providing a second housing substrate, and forming the second housing substrate over the first and second portions. | 02-17-2011 |
20110115974 | Integrated lens and chip assembly for a digital camera - A integrated camera module ( | 05-19-2011 |
20110299848 | Camera Module with Premolded Lens Housing and Method of Manufacture - A novel digital camera module includes an image capture device, a circuit substrate, a lens unit and a housing that is mounted to the circuit substrate before the image capture device is mounted to the circuit substrate. In one particular embodiment, the housing is formed onto the circuit substrate via molding. The housing includes a bore to receive the lens unit, with the diameter of the bore being larger than the diagonal of the image capture device such that image capture device can be mounted to the circuit substrate through the bore. In another particular embodiment, the circuit substrate includes an aperture so as to facilitate the flip-chip bonding of the image capture device. The order in which the image capture device and the housing are coupled to the circuit substrate helps prevent damage to the image capture device during the mounting of the housing to the circuit substrate. | 12-08-2011 |
20140047711 | METHOD FOR MOUNTING PROTECTIVE COVERS OVER IMAGE CAPTURE DEVICES AND DEVICES MANUFACTURED THEREBY - A method for manufacturing camera modules including image capture devices with protective covers is disclosed. The method includes providing a unitary transparent substrate including a plurality of individual protective covers, providing a unitary component substrate including a plurality of individual component parts, bonding the unitary transparent substrate to the unitary component substrate, dividing the transparent substrate into a plurality of discrete protective covers, and separating the component parts from one another. According to one particular method, the component substrate is a semiconductor wafer having a plurality of integrated electronic image capture devices formed therein. According to another particular method, the component substrate is a circuit board having a plurality of individual device circuit boards formed therein. | 02-20-2014 |
Patent application number | Description | Published |
20100215021 | ACCESS NETWORK HANDOVER FOR A MOBILE TELEVISION SYSTEM - A method and apparatus are described for content delivery, including receiving content from a first network, moving into a coverage area of a second network, performing a handover, receiving content from the second network and dropping any duplicate content packets. Also described are a method and apparatus for content delivery including receiving content from a first network, performing a handover, receiving content from a second network, determining if any content is missing and requesting the missing content. | 08-26-2010 |
20130044916 | METHOD AND APPARATUS OF PUSH & PULL GESTURE RECOGNITION IN 3D SYSTEM - The present invention provides method and apparatus of PUSH & PULL gesture recognition in 3D system. The method comprising determining whether the gesture is PUSH or PULL as a function of distances from the object performing the gesture to the cameras and the characteristics of moving traces of the object in the image planes of the two cameras. | 02-21-2013 |
20130286170 | METHOD AND APPARATUS FOR PROVIDING MONO-VISION IN MULTI-VIEW SYSTEM - It is provided a method for providing mono-vision in a multi-view system comprising at least two views of the same scene and at least one viewing zone, wherein, each viewing zone is provided with two views, and the at least two views are arranged in a way that two adjacent views among the at least two views are provided to each viewing zone so as to provide stereo-vision. The method comprises the steps of receiving an instruction requesting a viewing zone to provide mono-vision; and rearranging the at least two views in a way that two views provided to the viewing zone that provides mono-vision are of the same view as one among the at least two views. An apparatus thereof is also provided. | 10-31-2013 |
Patent application number | Description | Published |
20100138869 | METHOD AND DEVICE FOR GENERATING ELECTRONIC SERVICE GUIDE - A method for generating Electronic Service Guide, comprising steps of: obtaining user information from a user in a digital video broadcasting network; generating a first Electronic Service Guide as a function of the user information, wherein the first Electronic Service Guide lists services provided by the digital video broadcasting network and associated with the user information; and sending the first Electronic Service Guide to the user. | 06-03-2010 |
20100202405 | ACCESS NETWORK HANDOVER FOR A MOBILE TELEVISION SYSTEM - A method and apparatus are described for performing a handover in a content delivery system, including performing the handover from a first network to a second network at a protocol layer determined based on whether a content stream identification file used by said first network is paired with a content stream identification file used by said second network. Also described are a method and apparatus for performing a handover in a content delivery system, including performing the handover from a first network to a second network at a protocol layer determined based on whether a same content stream identification file used by the first network is used by the second network. Further described are a method and apparatus for performing a handover in a content delivery system, including performing the handover from a first network to a second network at one of an application layer, a network layer and a media access control layer. | 08-12-2010 |
20100250655 | Methods for delivering and receiving interactive multimedia - A method used in a service providing device for delivering interactive multimedia content to a plurality of client devices, comprising: receiving a request for the interactive multimedia content, from at least one of the plurality of client devices; disabling the plurality of client devices from sending the request to the service providing device, according to a predetermined condition; and delivering the interactive multimedia content to the plurality of client devices. | 09-30-2010 |