Rodionov
Galina Rodionov, Yavne IL
Patent application number | Description | Published |
---|---|---|
20110117085 | MONOCLONAL ANTIBODIES FOR TUMOR TREATMENT - The present invention relates to methods for inhibiting tumor growth, increasing survival of a subject having a tumor and inducing protection against tumor recurrence in a mammal. The methods comprise administering a humanized monoclonal antibody comprising CDR regions derived from the murine monoclonal antibody designated mBAT-1, in combination with at least one chemotherapeutic agent. | 05-19-2011 |
20140302032 | MONOCLONAL ANTIBODIES FOR TUMOR TREATMENT - A method of treating a tumor or enhancing survival of a subject having a tumor. The method includes (i) administering to a subject in need thereof an effective amount of a humanized monoclonal antibody or a fragment thereof, wherein the antibody or the fragment thereof has all complementarity determining regions of murine monoclonal antibody BAT (mBAT-1) and a framework region (FR) from an acceptor human immunoglobulin, or modified therefrom; and (ii) administering to the subject an effective amount of at least one chemotherapeutic agent selected from the group consisting of: 5-fluorouracil, cytarabine, oxaliplatin, paclitaxel and combinations thereof. The humanized antibody is administered between 1 and 30 days after commencing chemotherapy or substantially simultaneously or concurrently or according to an overlapping schedule with the at least one chemotherapeutic agent to thereby treat the tumor or enhance the survival of the subject having the tumor. | 10-09-2014 |
Igor Leonidovich Rodionov, Pushchino RU
Patent application number | Description | Published |
---|---|---|
20090142364 | Method for finding novel peptide immunostimulatory adjuvants, compositions and methods of use - The invention describes production of an adjuvant with biological activities related to N-acetylglucosaminyl-β1-4-N-acetylmuramyl-alanyl-D-isoglutamine (GMDP), a commonly used enhancer of the immune response. It was found in the present invention that the drawbacks of GMDP can be avoided by replacing it with a peptide that does not have any direct structural relationship with GMDP. | 06-04-2009 |
Igor Leonidovich Rodionov, Moscow RU
Patent application number | Description | Published |
---|---|---|
20120021430 | FUNCTIONAL LIPID CONSTRUCTS - The invention relates to methods for effecting qualitative and quantitative changes in the functional moieties expressed at the surface of cells and multi-cellular structures, and functional lipid constructs for use in such methods. In particular, the invention relates to functional lipid constructs and their use in diagnostic and therapeutic applications, including serodiagnosis, where the functional moiety is a carbohydrate, peptide, chemically reactive group, conjugator or fluorophore. | 01-26-2012 |
20140350217 | FUNCTIONAL LIPID CONSTRUCTS - The invention relates to methods for effecting qualitative and quantitative changes in the functional moieties expressed at the surface of cells and multi-cellular structures, and functional lipid constructs for use in such methods. In particular, the invention relates to functional lipid constructs and their use in diagnostic and therapeutic applications, including serodiagnosis, where the functional moiety is a carbohydrate, peptide, chemically reactive group, conjugator or fluorophore. | 11-27-2014 |
Igor Leonidovich Rodionov, Puschino RU
Patent application number | Description | Published |
---|---|---|
20140161723 | IN VIVO METHODS OF MONITORING BIODISTRIBUTION - Functional-lipid constructs of the structure F-S-L are disclosed, wherein F comprises a tyrosine or histidine residue, S is a spacer covalently linking F to L and L is a lipid. The functional residue may be iodinated and used to radiolabel a biological entity with 1251 and the iodinated constructs are used in a non-invasive method of monitoring the distribution of a biological entity in vivo. | 06-12-2014 |
Mikhail Rodionov, North York CA
Patent application number | Description | Published |
---|---|---|
20150271988 | METERING APPARATUSES FOR SECTIONAL CONTROL - A metering apparatus for distributing an agricultural product in a field has a meterbox configured for association with a hopper for receiving agricultural product from the hopper. A rotatable metering element is disposed within a chamber in the meterbox, and the rotating metering element is configured to deliver the agricultural product at a regulated rate from the hopper through the chamber to a product distribution line. Delivery of the agricultural product to the product distribution line may be selectively stopped by a reversibly inflatable seal between the metering element and an outlet to the distribution line, a reversible seal formed by contact between the metering element and an inlet from the hopper to the chamber, or a disengagement structure for disengaging the agricultural product from the metering element while the metering element continues to rotate. | 10-01-2015 |
Mikhail Rodionov, Markham CA
Patent application number | Description | Published |
---|---|---|
20090027106 | Substantially Zero Temperature Coefficient Bias Generator - In an embodiment, a bias generator circuit comprises a first circuit and a second circuit. The first circuit includes a first input coupled to a voltage source and a first output that provides a first output current having a substantially non-zero temperature coefficient. The first circuit comprises a first transistor and a second transistor. The second circuit includes a second input that receives the first output current from the first circuit and a second output that provides a second output current. The second circuit comprises a third transistor and a fourth transistor. The second output current has a substantially zero temperature coefficient dependent on (i) a difference between an effective channel size of the first transistor and an effective channel size of the second transistor, and (ii) a difference between an effective channel size of the third transistor and an effective channel size of the fourth transistor. | 01-29-2009 |
Mikhail Rodionov, Toronto CA
Patent application number | Description | Published |
---|---|---|
20110132627 | RESILIENTLY MOUNTED AGRICULTURAL TOOL AND IMPLEMENT THEREWITH - Disclosed are mounting means for agricultural tools, for example tillage assemblies, that comprise a resilient element and a horizontal pivot axis. This allows upward and rearward deflection of a tillage blade of the assembly in response to impact with obstacles. Tillage implements comprising the foregoing assemblies are also disclosed. In certain embodiments, the assemblies advantageously allow lateral deflection of at least a support arm of the assembly in response to impact with obstacles, which may be enhanced by providing a pivot means of the assembly with a resilient bushing. The resilient element and/or the resilient bushing may comprise elastomeric materials. | 06-09-2011 |
Mikhail Rodionov, Ebina-Shi JP
Patent application number | Description | Published |
---|---|---|
20140020387 | POWER GENERATING SYSTEM - In one embodiment, a power generating system includes; a flow dividing unit configured to divide a first heat medium supplied thereto to a first flow path and a second flow path; and a heat accumulating unit configured to accumulate the first heat medium sent thereto via the second flow path and deliver the first heat medium at a temporally leveled flow rate. The system further includes: a heat exchanging unit configured to transfer heat from the first heat medium sent thereto via the first flow path and the first heat medium delivered thereto from the heat accumulating unit, to a second heat medium that is lower in boiling point than the first heat medium; and a turbine configured to rotationally move with the second heat medium to which heat has been transferred by the heat exchanging unit. | 01-23-2014 |
20140033707 | POWER PLANT AND HEAT SUPPLY METHOD - According to one embodiment, a power plant includes a solar heat collector which collects solar heat and then supplies the solar heat to a heat medium. The power plant includes a heat exchanger which changes a secondary medium into steam by heat exchange with the heat medium. The power plant includes a turbine. The power plant includes a temperature sensor which detects the temperature of the heat medium. The power plant includes and a controller which supplies the heat medium with heat obtained by the conversion of an output variation component having a period shorter than a predetermined value in electricity generated by a wind power generator when the temperature does not satisfy a predetermined condition associated with the driving of the turbine. | 02-06-2014 |
20140116046 | POWER GENERATING SYSTEM - A flasher separates a geothermal fluid into steam and hot water. A steam turbine is driven by being supplied with the separated steam as a working medium. An evaporator is supplied with the steam from the steam turbine as a first heating medium, which is thereafter supplied to a first preheater via the evaporator. A superheater is supplied with the hot water separated by the flasher as a second heating medium, which is thereafter supplied to a second preheater via the superheater. A medium turbine is driven by being supplied, as a working medium, with a low-boiling-point medium having been heat-exchanged sequentially in the first preheater, the second preheater, the evaporator, and the superheater. In the evaporator and the first preheater, the low-boiling-point medium and the first heating medium are heat-exchanged. In the superheater and the second preheater, the low-boiling-point medium and the second heating medium are heat-exchanged. | 05-01-2014 |
Mikhail Rodionov, Ebina JP
Patent application number | Description | Published |
---|---|---|
20150145254 | POWER GENERATION SYSTEM - Electric power obtained by wind power generation is used effectively. A power generation system in an embodiment includes: a wind power generation apparatus; a solar thermal power generation apparatus; and an electrothermal converting unit. The solar thermal power generation apparatus includes: a heater heating a heating medium by solar heat; and a heat exchanger exchanging heat of the heating medium heated by the heater and heat of a working fluid to operate a drive mechanism of a power generator. The electrothermal converting unit converts part of electric power generated by the wind power generation apparatus into heat to heat the heating medium. | 05-28-2015 |
Petr Ivanovich Rodionov, Moskovskaya Obl. RU
Patent application number | Description | Published |
---|---|---|
20090312235 | Method for producing insulin in the form of an oral preparation - The invention belongs to pharmacology and medicine, particularly, to endocrinology. | 12-17-2009 |
Valentin O. Rodionov, Rockville, MD US
Patent application number | Description | Published |
---|---|---|
20100197871 | LIGANDS FOR COPPER-CATALYZED AZIDE-ALKYNE CYCLOADDITION REACTIONS - Ligands useful for promoting copper-catalyzed azide-alkyne cycloaddition reactions comprise a compound represented by structural Formula (I) as described in the specification, wherein in Formula (I) Z | 08-05-2010 |