Patent application number | Description | Published |
20100028979 | METHODS AND APPARATUS FOR ORGAN SUPPORT - An organ support apparatus includes: (a) a fluid circuit defining upstream and downstream legs adapted to be connected to an organ to be supported; (b) a circulation pump connected to the fluid circuit for circulating a process fluid through the fluid circuit and the organ; and (c) a first waveform generator connected to the fluid circuit for impressing a preselected pressure waveform on the process fluid. | 02-04-2010 |
20100030211 | IRREVERSIBLE ELECTROPORATION TO TREAT ABERRANT CELL MASSES - The present invention provides methods, devices, and systems for in vivo treatment of cell proliferative disorders. The invention can be used to treat solid tumors, such as brain tumors. The methods rely on non-thermal irreversible electroporation (IRE) to cause cell death in treated tumors. | 02-04-2010 |
20110106221 | TREATMENT PLANNING FOR ELECTROPORATION-BASED THERAPIES - The present invention provides systems, methods, and devices for electroporation-based therapies (EBTs). Embodiments provide patient-specific treatment protocols derived by the numerical modeling of 3D reconstructions of target tissue from images taken of the tissue, and optionally accounting for one or more of physical constraints or dynamic tissue properties. The present invention further relates to systems, methods, and devices for delivering bipolar electric pulses for irreversible electroporation exhibiting reduced or no damage to tissue typically associated with an EBT-induced excessive charge delivered to the tissue. | 05-05-2011 |
20120116152 | ARTICULATING ORGAN SUPPORT - An organ support apparatus includes: an enclosure having a floor, opposed side walls, opposed end walls, and a lid; a first support pad disposed on the floor of the enclosure, the first support pad comprising a plurality of inflatable and flexible chambers; and an inflation apparatus coupled to the chambers and operable to individually inflate or deflate each chamber. | 05-10-2012 |
20130102059 | METHODS AND APPARATUS FOR ORGAN SUPPORT - An organ support apparatus includes: (a) a fluid circuit defining upstream and downstream legs adapted to be connected to an organ to be supported; (b) a circulation pump connected to the fluid circuit for circulating a process fluid through the fluid circuit and the organ; and (c) a first waveform generator connected to the fluid circuit for impressing a preselected pressure waveform on the process fluid. | 04-25-2013 |
20130253415 | IRREVERSIBLE ELECTROPORATION USING TISSUE VASCULATURE TO TREAT ABERRANT CELL MASSES OR CREATE TISSUE SCAFFOLDS - The present invention relates to the field of medical treatment of diseases and disorders, as well as the field of biomedical engineering. Embodiments of the invention relate to the delivery of Irreversible Electroporation (IRE) through the vasculature of organs to treat tumors embedded deep within the tissue or organ, or to decellularize organs to produce a scaffold from existing animal tissue with the existing vasculature intact. In particular, methods of administering non-thermal irreversible electroporation (IRE) in vivo are provided for the treatment of tumors located in vascularized tissues and organs. Embodiments of the invention further provide scaffolds and tissues from natural sources created using IRE ex vivo to remove cellular debris, maximize recellularization potential, and minimize foreign body immune response. The engineered tissues can be used in methods of treating subjects, such as those in need of tissue replacement or augmentation. | 09-26-2013 |
20130338627 | FIBER ARRAY FOR OPTICAL IMAGING AND THERAPEUTICS - The present invention relates to the field of optical imaging and therapeutics. More particularly, embodiments of the present invention provide minimally-invasive Fiberoptic Microneedle Devices (FMDs) for light-based therapeutics, which physically penetrate tissue and deliver light directly into the target area below the skin surface. Embodiments of the invention enable depth-selective and deep photothermal therapeutics and include methods of treating cancer, methods of re-shaping or removing adipose tissue, and methods of delivering drugs or co-delivering drugs and energy to selected tissue. | 12-19-2013 |
Patent application number | Description | Published |
20090036016 | NONWOVEN FROM BULKED FILAMENT TOW - A nonwoven material has a plurality of randomly oriented and bulked crimped filaments, a plurality of point bonds interconnecting said crimped filaments into a fixed, 3-dimensional structure, and either a surface portion of said fixed, 3-dimensional structure having a greater density than an inner portion of said 3-dimensional structure or an external surface of said fixed, 3-dimensional structure being substantially free of any protruding filaments. The nonwoven material is made by: bulking a filament tow, fixing the bulked tow into a 3-dimensional structure, and calendering the 3-dimensional structure. | 02-05-2009 |
20090151738 | DEGRADABLE CIGARETTE FILTER - A degradable cigarette filter includes a filter element of a bloomed cellulose acetate tow, a plug wrap surrounding the filter element, and either a coating or a pill in contact with the tow. The coating and/or pill may be composed of a material adapted to catalyze hydrolysis of the cellulose acetate tow and a water-soluble matrix material. The material may be an acid, an acid salt, a base, and/or a bacterium adapted to generate an acid. The coating may be applied to the tow, the plug wrap, or both. The pill may be placed in the filter element. When water contacts the water-soluble matrix material, the material adapted to catalyze hydrolysis is released and catalyzes the hydrolysis, and subsequent degradation, of the cellulose acetate tow. The foregoing is also applicable to articles made of cellulose esters. | 06-18-2009 |
20090287131 | WOUND CARE PRODUCT MADE FROM BULKED FILAMENT TOW - A wound care product is a nonwoven fabric made of filaments bulked from a tow and fixed into a 3-dimensional structure. | 11-19-2009 |
20110174324 | DEGRADABLE CIGARETTE FILTER: PILL WITH MULTILAYERED COATING - A degradable cigarette filter includes a filter element of a bloomed cellulose acetate tow and a plug wrap surrounding the filter element, and a pill dispersed in the tow. The pill includes a material adapted to catalyze hydrolysis of the cellulose acetate tow that is encapsulated with an inner layer of a water soluble or water permeable material and an outer layer of a cellulose acetate having a D.S. in the range of 2.0-2.6. | 07-21-2011 |
20110240045 | ENVIRONMENTALLY DEGRADABLE CIGARETTE FILTER - An environmentally degradable cigarette filter includes a filter element of a bloomed cellulose acetate tow and a plug wrap surrounding said filter element. A weak organic acid and a pH adjusted inorganic ester salt are encapsulated in a matrix material which is in contact with the tow. The pH adjusted inorganic ester salt has a pH less than or equal to 8. When the cigarette filter is discarded into the environment, water liberates the weak acid and the ester salt from the matrix material. The weak acid hydrolyzes the ester liberating a strong acid. The strong acid catalyzes the degradation of the cellulose acetate tow. (The weak acid also hydrolyzes the cellulose acetate tow, but after the strong acid is generated, the strong acid becomes the dominant acid catalyst for the cellulose acetate tow degradation.) | 10-06-2011 |
20130032158 | Apparatuses, Systems, and Associated Methods for Forming Porous Masses for Smoke Filters - High-throughput production methods for manufacturing porous masses suitable for use in conjunction with smoking devices may include continuously combining a matrix material and a paper wrapper to form a desired cross-sectional shape where the matrix material is confined by the paper wrapper, the matrix material comprising a binder particle and an active particle; heating at least a portion of the matrix material so as to bind the matrix material at a plurality of contact points, thereby forming a porous mass length, wherein heating involves irradiating with microwave radiation at least a portion of the matrix material; cooling the porous mass length; and cutting the porous mass length radially thereby producing a porous mass. | 02-07-2013 |
20130046089 | ACETYLATION OF CELLULOSE IN DENSIFIED GAS - Cellulose acetates and processes for producing same. The process involves esterifying a cellulose containing material in the presence of a densified gas such as supercritical carbon dioxide to form a cellulose acetate product having a degree of substitution less than 3. The cellulose acetate preferably is sulfate-free. | 02-21-2013 |
20130066250 | WOUND CARE PRODUCT MADE FROM BULKED FILAMENT TOW - A wound care product is a nonwoven fabric made of filaments bulked from a tow and fixed into a 3-dimensional structure. | 03-14-2013 |
20130214447 | Apparatuses, Systems, and Associated Methods for Forming Porous Masses for Smoke Filter - A system for producing porous masses may include a mold cavity disposed along the material path, at least one hopper before at least a portion of the mold cavity for feeding a matrix material to the material path, a heat source in thermal communication with at least a first portion of the material path, and a cutter disposed along the material path after the first portion of the material path. | 08-22-2013 |
20130220349 | DEFORMABLE TABLET WITH WATER TRIGGERED CATALYST RELEASE - A tablet contains reagents with catalytic activity, release of which is triggered by exposure of the tablet to water. A malleable capsule includes: (a) a flexible polymer; (b) a plasticizer; and (c) a catalyst disposed within the capsule, wherein a portion of the catalyst is released from the capsule upon exposure of the capsule to water. | 08-29-2013 |
20130221563 | Apparatuses, Systems, and Associated Methods for Forming Porous Masses for Smoke Filter - A system for producing porous masses may include a mold cavity disposed along the material path, at least one hopper before at least a portion of the mold cavity for feeding a matrix material to the material path, a heat source in thermal communication with at least a first portion of the material path, and a cutter disposed along the material path after the first portion of the material path. | 08-29-2013 |
20130240133 | NONWOVEN FROM BULKED FILAMENT TOW - A nonwoven material has a plurality of randomly oriented and bulked crimped filaments, a plurality of point bonds interconnecting said crimped filaments into a fixed, 3-dimensional structure, and either a surface portion of said fixed, 3-dimensional structure having a greater density than an inner portion of said 3-dimensional structure or an external surface of said fixed, 3-dimensional structure being substantially free of any protruding filaments. The nonwoven material is made by: bulking a filament tow, fixing the bulked tow into a 3-dimensional structure, and calendering the 3-dimensional structure. | 09-19-2013 |
20130298923 | Apparatuses, Systems, and Associated Methods for Forming Porous Masses for Smoke Filter - A system for producing porous masses may include a mold cavity disposed along the material path, at least one hopper before at least a portion of the mold cavity for feeding a matrix material to the material path, a heat source in thermal communication with at least a first portion of the material path, and a cutter disposed along the material path after the first portion of the material path. | 11-14-2013 |
20140070465 | APPARATUSES, SYSTEMS, AND ASSOCIATED METHODS FOR FORMING POROUS MASSES FOR SMOKE FILTERS - High-throughput production apparatuses, systems, and associated methods may include pneumatic dense phase feeding. For example, a method may involve feeding via pneumatic dense phase feeding a matrix material into a mold cavity to form a desired cross-sectional shape, the matrix material comprising a binder particle and an active particle; heating (e.g., via microwave irradiation) at least a portion of the matrix material so as to bind the matrix material at a plurality of contact points thereby forming a porous mass length; cooling the porous mass length; and cutting the porous mass length radially thereby producing a porous mass. In some instances, the matrix material may include a plurality of active particles, a plurality of binder particles (optionally having a hydrophilic surface modification), and optionally a microwave enhancement additive. | 03-13-2014 |
20140076340 | APPARATUSES, SYSTEMS, AND ASSOCIATED METHODS FOR FORMING POROUS MASSES FOR SMOKE FILTERS - High-throughput production apparatuses, systems, and associated methods may include pneumatic dense phase feeding. For example, a method may involve feeding via pneumatic dense phase feeding a matrix material into a mold cavity to form a desired cross-sectional shape, the matrix material comprising a binder particle and an active particle; heating (e.g., via microwave irradiation) at least a portion of the matrix material so as to bind the matrix material at a plurality of contact points thereby forming a porous mass length; cooling the porous mass length; and cutting the porous mass length radially thereby producing a porous mass. In some instances, the matrix material may include a plurality of active particles, a plurality of binder particles (optionally having a hydrophilic surface modification), and optionally a microwave enhancement additive. | 03-20-2014 |
20140261475 | APPARATUSES, SYSTEMS, AND ASSOCIATED METHODS FOR FORMING ORGANIC POROUS MASSES FOR FLAVORED SMOKE FILTERS - Organic porous masses may be used in flavored smoke filters. Production of organic porous masses may involve introducing a matrix material into a mold cavity, the matrix material comprising a plurality of binder particles, a plurality of organic particles, and a microwave enhancement additive; heating at least a portion of the matrix material so as to bind the matrix material at a plurality of contact points, thereby forming an organic porous mass length, wherein heating involves irradiating with microwave radiation the at least a portion of the matrix material; and cutting the organic porous mass length radially thereby yielding an organic porous mass. | 09-18-2014 |
20140261502 | SMOKE FILTERS FOR REDUCING COMPONENTS IN A SMOKE STREAM - Smoke filters that reduce the concentration of carbon monoxide and phenols in a smoke stream may include a porous mass section comprising a plurality of active particles, a plurality of binder particles, and an active coating disposed on at least a portion of the active particles and the binder particles, wherein the active particles and the binder particles are bound together at a plurality of contact points; and a filter section. In some instances, a filter may include a porous mass section comprising a plurality of active particles and a plurality of binder particles, wherein the active particles and the binder particles are bound together at a plurality of contact points without an adhesive; and a filter section comprising an active dopant. | 09-18-2014 |
20140263301 | CONFIGURABLE SHIPPING CONTAINER - Shipping containers for porous masses may include a bottom lid having a rectangular lid bottom and four bottom rims that are each continuous with the lid bottom; a tray comprising a tray bottom and four tray sidewalls that are each continuous with the tray bottom defining an interior with an open top; and a top lid having a rectangular lid top and four top rims that are each continuous with the lid top, wherein the tray is configured to be placed on a bottom lid with the bottom rims surrounding a portion of the tray with a top lid placed over the top of the tray with the top rims surrounding a portion of the tray. | 09-18-2014 |
20150014405 | TAGGED CELLULOSE ESTER FILMS - Cellulose ester films may include taggants to provide for product authentication and counterfeit identification, especially in packaging applications. In some instances, a tagged cellulose ester film may include cellulose ester, a plasticizer, and a taggant, wherein the taggant comprises at least one taggant component selected from the group consisting of an elemental marker, a molecular fluorophore, a particulate fluorophore, and any combination thereof. | 01-15-2015 |
20150017419 | Tagged Porous Masses - Porous masses that include taggants may provide for product authentication and counterfeit identification, especially products like smoking device filters and smoking devices. In some instances, a tagged porous mass may include a plurality of binder particles; a taggant that comprises at least one taggant component selected from the group consisting of an elemental marker, a molecular fluorophore, a particulate fluorophore, and any combination thereof; a plurality of second particles, wherein the second particles comprise at least one selected from the group consisting of active particles, organic particles, and any combination thereof; and wherein the binder particles are bound to the second particles at sintered contact points. | 01-15-2015 |