Patent application number | Description | Published |
20090008452 | PRODUCT PACKAGING INCLUDING DIGITAL DATA - Light sensitive materials applied in shipping materials, including security seals and tear tape, for authentication, discrimination and recognition of items. | 01-08-2009 |
20090035539 | PIRACY PROTECTED RECORDING MEDIA - An optical medium piracy system employing a state-change material in association with a digital data indicia, wherein when state-change material is activated to change state, the optical medium moves from an unreadable to a readable condition, or from a less readable to more readable condition. | 02-05-2009 |
20100254535 | REMOTE CIRCUIT LOCKING SWITCH SYSTEM - A method and apparatus for remotely controlling access to the components of an optically interconnected information processing infrastructure is presented. Access to the infrastructure is controlled independently of the infrastructure operating system. | 10-07-2010 |
20110192239 | DEVICES FOR COLLECTION AND STABILIZATION OF BIOMARKERS IN LIQUID SAMPLES - Device for collection and stabilization of biomarkers in liquid samples. In at least one embodiment of a fluid collection device, the device comprises a housing having a top end, a bottom end, and a tubular compartment therethrough, a swab connected to bottom end of the housing and in fluid communication with the tubular compartment, the swab designed to collect a body fluid, and a stabilizing agent contained within the fluid collection device, the stabilizing agent capable of completely or substantially preventing the degradation or inactivation of a diagnostic agent in a bodily fluid upon receipt of the bodily fluid into the fluid collection device. Optionally, the stabilizing agent may be coupled to the swab, and/or contained within the tubular compartment of the housing. | 08-11-2011 |
20110194996 | TRANSPORT CONTAINER FOR STABILIZED LIQUID SAMPLES - Transport container for stabilized liquid samples. In at least one embodiment of a system for the transport of biological samples, the transport system comprises an inner container having at an opening and least one rigid chamber for containing a body fluid comprising at least one diagnostic marker, a stabilizing agent contained within the inner container, the stabilizing agent capable of completely or substantially preventing the degradation or inactivation of a diagnostic agent for at least twenty four hours following interaction with the diagnostic agent, a securing device for closing the opening of the inner container, wherein the stabilizing agent is linked to a solid support, and wherein the inner container is comprised of a material resistant to fracture. | 08-11-2011 |
20110195394 | SYSTEMS AND METHODS FOR DIAGNOSING VIRAL INFECTIONS - Systems and methods for diagnosing viral infections. According to at least one embodiment of a stabilizing system of the present disclosure, the system comprises a stabilizing agent useful to completely or substantially prevent degradation or inactivation of a diagnostic marker for a viral infection in a body fluid comprising the diagnostic marker and a detection agent capable of detecting the diagnostic marker | 08-11-2011 |
20110195395 | RINSE COMPOSITION FOR THE STABILIZATION OF DIAGNOSTIC BIOMARKERS - Rinse composition for the stabilization of diagnostic biomarkers. In at least one embodiment of a rinse useful to stabilize a diagnostic marker, the rinse comprises a stabilizing agent useful to completely or substantially prevent degradation or inactivation of a diagnostic marker in saliva, and a liquid. | 08-11-2011 |
20110195396 | CHEWABLE COMPOSITIONS FOR THE STABILIZATION OF DIAGNOSTIC BIOMARKERS - Chewable compositions for the stabilization of diagnostic biomarkers. In at least one embodiment of a chewing gum composition useful to stabilize a diagnostic marker, the a chewing gum composition comprises a stabilizing agent useful to completely or substantially prevent degradation or inactivation of a diagnostic marker in saliva, and a liquid. | 08-11-2011 |
20110195397 | DRINK MIXTURE FOR THE STABILIZATION OF DIAGNOSTIC BIOMARKERS - Drink mixture for the stabilization of diagnostic biomarkers. In at least one embodiment of an ingestible beverage useful to stabilize a diagnostic marker, the rinse comprises a stabilizing agent useful to completely or substantially prevent degradation or inactivation of a diagnostic marker in saliva, and a liquid. | 08-11-2011 |
20110195398 | SYSTEMS AND METHODS FOR DETECTING INSULIN RESISTANCE BIOMARKERS - Systems and methods for detecting insulin resistance biomarkers. At least one embodiment of a system of the present disclosure comprises a stabilizing agent useful to completely or substantially prevent degradation or inactivation of a diagnostic marker for insulin resistance or glucose intolerance in a body fluid comprising the diagnostic marker, and a detection agent capable of detecting the diagnostic marker. | 08-11-2011 |
20110195399 | SYSTEMS AND METHODS FOR THE INHIBITION OF GALACTOSE OXIDASE - Systems and methods for the inhibition of galactose oxidase. According to least one embodiment of a stabilizing system of the present disclosure, the system comprises a stabilizing agent useful to completely or substantially prevent degradation or inactivation of a diagnostic marker by galactose oxidase in a body fluid including the diagnostic marker. The stabilizing system also includes a detection agent capable of detecting the diagnostic marker. | 08-11-2011 |
20110195400 | SYSTEMS AND METHODS FOR DIAGNOSING CANCER - Systems and methods for diagnosing cancer. According to at least one embodiment of a stabilizing system of the present disclosure, the system comprises a stabilizing agent useful to completely or substantially prevent degradation or inactivation of a diagnostic marker for cancer in a body fluid comprising the diagnostic marker and a detection agent capable of detecting the diagnostic marker. | 08-11-2011 |
20110195401 | SYSTEMS AND METHODS FOR DETERMINING FOOD ALLERGIES - Systems and methods for determining food allergies. In at least one embodiment of a system of the present disclosure, the system comprises a stabilizing agent useful to completely or substantially prevent degradation or inactivation of a diagnostic marker for a food allergy in a body fluid comprising the diagnostic marker and a detection agent capable of detecting the diagnostic marker. | 08-11-2011 |
20110195402 | SYSTEMS AND METHODS FOR DETECTING DRUG USE - Systems and methods for detecting drug use. In at least one embodiment of a system of the present disclosure, the system comprises a stabilizing agent useful to completely or substantially prevent degradation or inactivation of a diagnostic marker indicative of drug use in a body fluid, comprising the diagnostic marker, and a detection agent capable of detecting the diagnostic marker. | 08-11-2011 |
20110195403 | SYSTEMS AND METHODS FOR FERTILITY ANALYSIS - Systems and methods for fertility analysis. In at least one embodiment of a system of the present disclosure, the system comprises a stabilizing agent useful to completely or substantially prevent degradation or inactivation of a diagnostic marker for fertility in a body fluid comprising the diagnostic marker, and a detection agent capable of detecting the diagnostic agent. In an exemplary embodiment, the stabilizing agent may be selected from the group consisting of a protease inhibitor, a DNase inhibitor, and a RNase inhibitor. | 08-11-2011 |
20110195404 | SYSTEMS AND METHODS FOR DETERMINING CALCIUM LEVELS - Systems and methods for determining calcium levels. In at least one embodiment of a system of the present disclosure, the system comprises a stabilizing agent useful to completely or substantially prevent degradation or inactivation of a diagnostic marker for circulating calcium in a body fluid comprising the diagnostic marker, and a detection agent capable of detecting the diagnostic agent. | 08-11-2011 |
20110195421 | METHODS OF IDENTIFYING BIOMARKERS FOR CANCER - Methods of Identifying Biomarkers for Cancer. According to at least one embodiment of a method of identifying diagnostic markers of cancer of the present disclosure, the method comprises the steps of contacting a body fluid of a diseased subject having a cancer with a stabilizing agent capable of completely or substantially preventing the degradation or inactivation of a diagnostic marker, analyzing the stabilized body fluid to determine at last one property of the diagnostic marker to create a cancer profile, comparing the cancer profile with a control profile of a healthy subject not having the cancer, wherein the control profile is created in a like manner to the cancer profile, and generating a cancer identifier panel from the compared cancer profile, wherein the cancer identifier panel contains at least one cancer diagnostic marker indicative of the cancer. | 08-11-2011 |
20110195422 | METHODS FOR DETERMINING THE EFFICIENCY OF A THERAPEUTIC - Methods for determining the efficiency of a therapeutic. In at least one embodiment of a method of determining the efficacy of a therapeutic compound, the method comprises the steps of treating a subject having a disease state with an effective amount of therapeutic compound, harvesting at least one cell from the subject following a treatment with the therapeutic compound, bringing the at least one cell into contact with a stabilizing compound capable of completely or substantially preventing the degradation or inactivation of a diagnostic marker for the disease state, analyzing the at least one stabilized cell for the at least one diagnostic marker, creating a marker profile from at least one result determined from analyzing the at least one stabilized cell, and comparing the marker profile with at least one previous marker profile to determine efficacy of the therapeutic compound on the disease state. | 08-11-2011 |
20110195423 | SYSTEMS AND METHODS FOR DIAGNOSING BACTERIAL INFECTIONS - Systems and methods for diagnosing bacterial infections. According to at least one embodiment of a system of the present disclosure, the system a stabilizing agent useful to completely or substantially prevent degradation or inactivation of a diagnostic marker for a bacterial infection in a body fluid comprising the diagnostic marker and a detection agent capable of detecting the diagnostic marker. | 08-11-2011 |
20110195424 | SYSTEMS AND METHODS FOR DIAGNOSING FUNGAL INFECTIONS - Systems and methods for diagnosing fungal infections. According to at least one embodiment of a stabilizing system of the present disclosure, the system comprises a stabilizing agent useful to completely or substantially prevent degradation or inactivation of a diagnostic marker for a fungal infection in a body fluid comprising the diagnostic marker and a detection agent capable of detecting the diagnostic marker. | 08-11-2011 |
20110195425 | SYSTEMS AND METHODS FOR DIAGNOSING PARASITE INFECTIONS - Systems and methods for diagnosing parasite infections. According to at least one embodiment of a stabilizing system of the present disclosure, a stabilizing system comprises a stabilizing agent useful to completely or substantially prevent degradation or inactivation of a diagnostic marker for a parasite infection in a body fluid comprising the diagnostic marker and a detection agent capable of detecting the diagnostic marker. | 08-11-2011 |
20110195427 | SYSTEMS AND METHODS FOR DETECTING PREGNANCY - Systems and methods for detecting pregnancy. In at least one embodiment of a system of the present disclosure, the system comprises a stabilizing agent useful to completely or substantially prevent degradation or inactivation of a diagnostic marker for pregnancy in a body fluid comprising the diagnostic marker, and a detection agent capable of detecting the diagnostic agent. | 08-11-2011 |
20110195439 | SYSTEMS AND METHODS FOR DETERMINING CARDIAC CONDITIONS - Systems and methods for determining cardiac conditions. According to at least one embodiment of a stabilizing system of the present disclosure, the system comprises a stabilizing agent useful to completely or substantially prevent degradation or inactivation of a diagnostic marker for cardiovascular disease in a body fluid comprising the diagnostic marker and a detection agent capable of detecting the diagnostic marker. | 08-11-2011 |
20110195440 | SYSTEMS AND METHODS FOR IDENTIFYING ALLERGIES - Systems and methods for identifying allergies. In at least one embodiment of a system of the present disclosure, the system comprises a stabilizing agent useful to completely or substantially prevent degradation or inactivation of a diagnostic marker for a non-food allergy in a body fluid comprising the diagnostic marker and a detection agent capable of detecting the diagnostic marker. | 08-11-2011 |
20110195487 | SAMPLE CONTAINER FOR BIOMARKER MAINTENANCE - Sample container for biomarker maintenance. In at least one embodiment of a system for stabilizing a diagnostic marker of the present disclosure, the system comprises a sample container having an opening and least one rigid chamber for containing a body fluid, the body fluid comprising at least one diagnostic marker, a stabilizing agent contained within the sample container, the stabilizing agent capable of completely or substantially preventing the degradation or inactivation of the diagnostic marker, and a securing device for closing the opening of the sample container, wherein the stabilizing agent is coupled to a solid support. In an exemplary embodiment of a system of the present disclosure, the stabilizing agent may be adsorbed to the solid support. | 08-11-2011 |
20110195488 | DEVICES FOR COLLECTION AND STABILIZATION OF BIOMARKERS IN LIQUID SAMPLES - Device for collection and stabilization of biomarkers in liquid samples. In at least one embodiment of a fluid collection device, the device comprises a first tube operable to receive a body fluid, a second tube operable to dispense a body fluid, and a suction device operably connected to the second opening of the first tube and the first end of the second tube, wherein the suction device is operable to produce negative pressure through the first tube and is operable to exert positive pressure through the second tube. An embodiment of the devices also comprises a stabilizing agent contained within the fluid collection device, the stabilizing agent capable of completely or substantially preventing the degradation or inactivation of a diagnostic agent in a body fluid upon receipt of the body fluid into the fluid collection device. | 08-11-2011 |
20110195491 | DEVICES AND SYSTEMS FOR BIOMARKER DETECTION - Devices and systems for biomarker detection. In at least one embodiment of a device for analyzing the presence or absence of a diagnostic marker to be detected in a body fluid, the device comprises a container, wherein the container houses a sample reservoir having a sample input port in fluid connection with at least one detector array, wherein the detector array comprises at least one detector comprising a reaction chamber comprising an immobilized capture molecule, a stabilizing agent contained within the sample reservoir, the stabilizing agent useful to completely or substantially prevent degradation or inactivation of a diagnostic marker, and a reagent contained within the detector array, the reagent capable of undergoing a colorimetric reaction or displaying an optically detectable signal and capable of reacting with the diagnostic marker. | 08-11-2011 |
20110195508 | SYSTEMS AND METHODS FOR HEMOGLOBIN ANALYSIS - Systems and methods for hemoglobin analysis. At least one embodiment of a stabilizing system comprises a stabilizing agent useful to completely or substantially prevent degradation or inactivation of a glycosylated hemoglobin (HbA1c) in a body fluid and a detection agent capable of detecting the HbA1c. | 08-11-2011 |
20110195851 | SYSTEMS AND METHODS FOR DETERMINING THERAPEUTIC POTENTIAL - Systems and methods for determining therapeutic potential. In at least one embodiment of a system of the present disclosure, the system comprises a detection platform, a computer processor and a database. The processor, in at least one embodiment of a method of the present disclosure, has and executes a software program operational to determine a binding characteristic of the detection agent and a stabilized diagnostic marker in each of the plurality of detection sites on the platform, compare the binding characteristic, and determining the stabilizing agent with the greatest effect on the binding characteristic between the detection agent and the diagnostic marker. Further, at least one embodiment of a system for determining the therapeutic potential of a therapeutic compound of the present disclosure is able to generate a binding record using the compared binding characteristics, and deliver the binding record to a recipient. | 08-11-2011 |
20110195855 | SYSTEMS AND METHODS FOR IMPROVING BIOMARKER AVAILABILITY - Systems and Methods for Improving Biomarker Availability. In at least one embodiment of a computer-implemented method of improving diagnostic marker availability, the method comprises the steps of introducing a predetermined diagnostic marker for cancer into a plurality of detection sites of a detection platform, introducing a stabilization agent into each of the plurality of detection sites containing the predetermined diagnostic marker for cancer, introducing a detection agent into each of the plurality of detection sites having a stabilized diagnostic agent, determining a binding characteristic of the detection agent and the stabilized diagnostic agent in each of the plurality of detection sites with a processor, and computationally comparing the binding characteristic among each of the plurality of detection sites with the processor, wherein the comparison of binding characteristics is capable of determining the stabilizing agent with the greater effect on the binding characteristic between the detection agent and the diagnostic agent. | 08-11-2011 |
20110195856 | METHODS OF DETERMINING STABILIZATION COMPOUNDS FOR PREDICTIVE BIOMARKERS - Methods of determining stabilization compounds for predictive biomarkers. According to at least one embodiment of a method of the present disclosure, the method comprises introducing a diagnostic marker and a stabilization agent to a detection platform, mixing the diagnostic marker and stabilization agent, and determining their binding characteristics. | 08-11-2011 |
20110195857 | SYSTEMS FOR ANALYZING STABILIZED BIOMARKERS - Systems for analyzing stabilized biomarkers. In at least one embodiment of a system for the detection of a diagnostic marker of the present disclosure, the system comprises a detection platform comprising a plurality of detection wells housed in a solid matrix, wherein the detection wells contain a plurality of diagnostic markers and at least one competitor molecule, wherein the plurality of diagnostic markers and at least one control molecule are each bound to a paramagnetic particle. An embodiment of the system of the present disclosure further comprises a detection system capable of receiving the detection platform, exerting a magnetic field upon a surface of the detection platform, and determining at least one characteristic of the diagnostic marker. | 08-11-2011 |
20110195858 | SYSTEMS AND METHODS OF ANALYZING BIOMARKER LEVELS - Systems and methods of analyzing biomarker levels. In at least one embodiment of a method of analyzing biomarker levels, the method comprises the steps of combining a body fluid comprising a diagnostic marker with a stabilization agent for an incubation period, introducing the stabilized body fluid into a detection platform, combining a detection agent with the stabilized body fluid, determining an interaction characteristic of the detection agent and the diagnostic marker of the stabilized body fluid using a detection device in communication with a processor, comparing the interaction characteristic with a plurality of indexed interaction records contained on a database in communication with the processor to determine an identity and concentration of the detection marker, generating a report of the identity and concentration of the detection marker in the body fluid, and delivering the report to a recipient. | 08-11-2011 |
20110195859 | SYSTEMS AND METHODS FOR THE DETECTION OF BIOMARKERS - System and methods for the detection of biomarkers. In at least one embodiment of a system for the detection of a diagnostic marker in a body fluid of the present disclosure, the system comprises a diagnostic device comprising a plurality of test wells, wherein each test well is capable of containing at least one detection agent, a detection device capable of interacting with the diagnostic device, wherein the detection device is capable of detecting an interaction between the at least one detection agent and a diagnostic marker in at least one of the plurality of test wells, and a stabilization agent contained within at least one of the plurality of test wells, the stabilization agent capable of completely or substantially preventing the degradation or inactivation of the detection agent or the diagnostic marker. | 08-11-2011 |
20110195871 | SYSTEMS AND METHODS OF SCREENING BIOMARKERS IN BODILY FLUIDS - Systems and methods of screening biomarkers in bodily fluids. According to at least one embodiment of the system for analyzing stabilizing agents of the present disclosure, the system comprises a detection platform comprising a plurality of detection sites each capable of receiving a diagnostic marker, a stabilization agent, and a detection agent. The system, in at least one embodiment, further comprises a detection device capable of determining a binding characteristic between the detection agent and the diagnostic marker in the detection sites. Further, the system may also be able to compare the binding characteristic among a plurality of detection markers to order the level of effect of the stabilizing agents assayed on the binding characteristic between the detection agent and the diagnostic agent. | 08-11-2011 |
20110195873 | SYSTEMS AND METHODS FOR THE DETECTION OF BIOMARKERS - Systems and methods for the detection of biomarkers. In at least one embodiment of a microarray system of the present disclosure, the microarray system comprises a microarray product comprising at least 100 diagnostic markers/cm | 08-11-2011 |
20110195874 | SYSTEMS AND METHODS FOR BIOMARKER ANALYSIS - Systems and methods of biomarker analysis. In at least one embodiment of a system for determining the therapeutic potential of a therapeutic compound the present disclosure, the system comprises a detection platform, a computer database capable of receiving a plurality of binding characteristics, a processor operably coupled to the computer database and the detection platform. In at least one embodiment, the processor has and executes a software program operational to determine a binding characteristic of the detection agent and a stabilized diagnostic agent in each of the plurality of detection sites, compare the binding characteristic among each of the plurality of detection sites, wherein the comparison of binding characteristics is capable of determining the stabilizing agent with the greatest effect on the binding characteristic between the detection agent and the diagnostic agent, generate a binding record using the compared binding characteristics, and deliver the binding record to a recipient. | 08-11-2011 |
20110196085 | BIOMARKER STABILIZING AGENTS - Biomarker stabilizing agents. In at least one embodiment of a stabilizing bead of the present disclosure, the stabilizing bead comprises a latex particle having a carboxylate group, and a stabilizing agent functionally coupled to the latex particle, wherein the stabilizing agent is capable of completely or substantially preventing the degradation or inactivation of a diagnostic agent in close proximity to the stabilizing agent. Optionally, an embodiment of a stabilizing bead may further comprise at least one of human serum albumin (HSA) and bovine serum albumin (BSA). Moreover, an embodiment of a stabilizing bead of the present disclosure may further comprise a linker group coupled to latex particle. | 08-11-2011 |
20120065896 | BIOLOGICAL AND CHEMICAL TEST MEDIA AND SYSTEM - An apparatus and method for performing medical, biological or chemical tests in the field is disclosed. In some embodiments, the test media comprises a special purpose optical disc which is read, after application of the test specimen and subsequent processing, using commonly available CD, DVD, High Definition DVD or Blu-Ray optical disc players. | 03-15-2012 |
20120164674 | DEVICES AND WASHES FOR BIOMARKER STABILIZATION - Herein are disclosed compositions, washes, rinses, devices, systems and methods for biomarker stabilization, in part in bodily fluids, as well as methods and formulations for improving the sampling and testing of fluids for biomarkers. Included in the disclosure are exemplary embodiments of rinses or washes containing a stabilizing agent to prevent the destruction of a diagnostic agent or biomarker and exemplary systems for the detection of diagnostic biomarkers in a bodily fluid | 06-28-2012 |
20130157373 | SYSTEMS AND METHODS FOR HEMOGLOBIN ANALYSIS - Systems and methods for hemoglobin analysis. At least one embodiment of a stabilizing system comprises a stabilizing agent useful to completely or substantially prevent degradation or inactivation of a glycosylated hemoglobin (HbA1c) in a body fluid and a detection agent capable of detecting the HbA1c. | 06-20-2013 |
20130184186 | SYSTEMS AND METHODS FOR THE DETECTION OF BIOMARKERS - Systems and methods for the detection of biomarkers. In at least one embodiment of a microarray system of the present disclosure, the microarray system comprises a microarray product comprising at least 100 diagnostic markers/cm | 07-18-2013 |
20130184187 | SYSTEMS AND METHODS FOR BIOMARKER ANALYSIS - Systems and methods of biomarker analysis. In at least one embodiment of a system for determining the therapeutic potential of a therapeutic compound the present disclosure, the system comprises a detection platform, a computer database capable of receiving a plurality of binding characteristics, a processor operably coupled to the computer database and the detection platform. In at least one embodiment, the processor has and executes a software program operational to determine a binding characteristic of the detection agent and a stabilized diagnostic agent in each of the plurality of detection sites, compare the binding characteristic among each of the plurality of detection sites, wherein the comparison of binding characteristics is capable of determining the stabilizing agent with the greatest effect on the binding characteristic between the detection agent and the diagnostic agent, generate a binding record using the compared binding characteristics, and deliver the binding record to a recipient. | 07-18-2013 |
20130339752 | REMOTE CIRCUIT LOCKING SWITCH SYSTEM - A method and apparatus for remotely controlling access to the components of an optically interconnected information processing infrastructure is presented. Access to the infrastructure is controlled independently of the infrastructure operating system. | 12-19-2013 |
20140155282 | METHODS OF DETERMINING STABILIZATION COMPOUNDS FOR PREDICTIVE BIOMARKERS - Methods of determining stabilization compounds for predictive biomarkers. According to at least one embodiment of a method of the present disclosure, the method comprises introducing a diagnostic marker and a stabilization agent to a detection platform, mixing the diagnostic marker and stabilization agent, and determining their binding characteristics. Additionally, the method may further comprise generating a report based on the binding characteristics and delivering the report to a recipient. | 06-05-2014 |