Patent application number | Description | Published |
20080227188 | Biosensor with Optically Matched Substrate - The matching of refractive index of a nanoporous membrane with an analyte solution used with the membrane for use in a sensor is described. Scattering of the excitation and/or emitted light is reduced by matching the refractive indices. This improves efficiency when the porous translucent membrane is used in flow-through or flow-over sensors such as biosensors. | 09-18-2008 |
20080245971 | Biosensors with Improved Sensitivity - A sensor is described for use with at least one optical detector ( | 10-09-2008 |
20080257071 | Microfluidic Device with Porous Membrane and an Unbranched Channel - The invention relates to a microfluidic device for detection of a substance in a sample fluid, and to a cartridge for performing a biological assay, containing such a device. The microfluidic device comprises two housing parts ( | 10-23-2008 |
20090126459 | FUNCTIONAL ASSEMBLY AND METHOD OF OBTAINING IT - The invention relates to a functional assembly, for instance a biosensor, and to a method to obtain it. The assembly comprises a functional element ( | 05-21-2009 |
20090130025 | APPARATUS AND METHODS FOR THE PRODUCTION OF ULTRASOUND CONTRAST AGENTS - Disclosed is a method of making gas bubbles in a liquid, the bubbles having substantially uniform size suitable for responding to ultrasound or other diagnostic tools. Gas (P | 05-21-2009 |
20090309049 | MULTI-COLOR BIOSENSOR - A detection system is described ( | 12-17-2009 |
20090311798 | SE(R)RS DISPLACEMENT ASSAY - A detection method is described for detecting an analyte, in particular nucleic acids, in a sample using SE(R)RS, without the need for labeling of the analyte. The detection method is based on the displacement of a labeled surrogate target probe from a capture probe by the analyte in the sample. The present invention also provides a corresponding detection system, to a disposable cartridge for use in such a system, and to a combination of surrogate target probe and capture probe. | 12-17-2009 |
20100055666 | BIOSENSOR WITH EVANESCENT WAVEGUIDE AND INTEGRATED SENSOR - The present invention is directed to a waveguide sensor as well as to an evanescent field induced evanescent field induced sensor system for use in diagnostic housing and an integrated waveguide sensor comprising: a waveguide layer,—capture compounds applied on the upper surface of said waveguide layer for | 03-04-2010 |
20100173131 | PHASE-SEPARATED COMPOSITE FOR MICROFLUIDIC APPLICATIONS - The invention relates to phase-separated composite for microfluidic applications, whereby the polymerization/phase separation is performed in such a way that a top-layer of a certain ratio to the height of the composite is achieved in order to ensure the stability of the composite. | 07-08-2010 |
20100266450 | MICROFLUIDIC DEVICE AND METHOD OF MANUFACTURING THE SAME AND SENSOR INCORPORATING THE SAME - The present invention provides a microf luidic device, for instance for molecular sieving or for detecting a target substance in a sample fluid. The device comprises a first substrate ( | 10-21-2010 |
20100270478 | DETECTION SYSTEM AND METHOD - A detection system, comprising: a radiation source ( | 10-28-2010 |
20110101243 | MICROARRAY CHARACTERIZATION SYSTEM AND METHOD - A system and method is described for detecting a plurality of analytes in a sample. The characterization system ( | 05-05-2011 |
20110168918 | DETECTION SYSTEM AND METHOD - A detection system combines an excitation radiation source ( | 07-14-2011 |
20120100630 | MIXER WITH ZERO DEAD VOLUME AND METHOD FOR MIXING - The invention relates to a micro fluidics system ( | 04-26-2012 |
20120115246 | MICROFLUIDIC DEVICE COMPRISING SENSOR - The invention relates to a microfluidic device for performing detection of a substance in a liquid sample, wherein a cavity ( | 05-10-2012 |
20120165219 | DEVICES AND METHODS FOR MICROARRAY SELECTION - The present invention relates to a device for the specific selection of target molecules, comprising: (a) at least one reaction zone comprising a microarray, wherein the microarray comprises a substrate, on which one or more species of capture molecules are immobilized, comprising one or more temperature control and/or regulating units for controlling and/or regulating the temperature within the zone; (b) at least one non-reaction zone comprising one or more temperature control and/or regulating units for controlling and/or regulating the temperature within the zone, which is in fluid connection with the reaction zone; and (c) at least one transportation means capable of generating and/or regulating a fluid flow between said reaction zone (a) and said non-reaction zone comprising one or more temperature control and/or regulating units (b). The present invention further relates to a device for the specific selection of target molecules wherein the immobilized capture molecules are organized in the microarray in the form of spots, elongated spots and/or lines. In a further aspect the present invention relates to a method of specifically selecting target molecules, comprising the introducing a medium to such a device, performing interaction reactions in a reaction zone, transporting not interacted or not bound target molecules to a zone allowing reactivation of the target molecules and performing additional interaction reactions with the reactivated target molecules at the reaction zone, as well as the use of such a device for specifically selecting target molecules, e.g. for target enrichment also referred to as microarray based genome selection (MGS) in the literature. | 06-28-2012 |
20120225446 | PREPARATION OF THIN LAYERS OF A FLUID CONTAINING CELLS FOR ANALYSIS - Apparatus for producing thin layers of a fluid sample for analysis, has a two dimensional array of analysis chambers ( | 09-06-2012 |
20150079585 | DNA SEQUENCING WITH REAGENT RECYCLING ON WIREGRID - The present invention relates to DNA sequencing with reagent cycling on the wiregrid. The sequencing approach suggested with which allows to use a single fluid with no washing steps. Based on strong optical confinement and of excitation light and of cleavage light, the sequencing reaction can be read-out without washing the surface. Stepwise sequencing is achieved by using nucleotides with optically cleavable blocking moietys. After read-out the built in nucleotide is deblocked by cleavage light through the same substrate. This ensures that only bound nucleotides will be unblocked. | 03-19-2015 |