Regula
Christoph Regula, Bremen DE
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20130280539 | Method for connecting substrates, and composite structure obtainable thereby - The invention relates to a method for connecting substrates including depositing a plasma polymer layer on each of a first and a second substrate by means of atmospheric pressure plasma and bringing the plasma polymer layers in contact with each other. In a variant of the method, only the first substrate is provided with a plasma polymer layer and connected to a second substrate, the surface of which can react with the plasma polymer layer. The invention further relates to composite structures which can be obtained with such methods. | 10-24-2013 |
Duane R. Regula, Forest Hill, MD US
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20080236360 | Cover for stringed instruments | 10-02-2008 |
Jack Regula, Chapel Hill, NC US
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20120166690 | MULTI-ROOT SHARING OF SINGLE-ROOT INPUT/OUTPUT VIRTUALIZATION - In a first embodiment of the present invention, a method for multi-root sharing of a plurality of single root input/output virtualization (SR-IOV) endpoints is provided, the method comprising: CSR redirection to a management processor which either acts as a proxy to execute the CSR request on behalf of the host or filters it and performs an alternate action, downstream routing of memory mapped I/O request packets through the switch in the host's address space and address translation with VF BAR granularity, upstream routing of requests originated by I/O devices by table lookup indexed by Requester ID, and requester ID translation using a fixed local-global RID offset. | 06-28-2012 |
20120167085 | SHARING MULTIPLE VIRTUAL FUNCTIONS TO A HOST USING A PSEUDO PHYSICAL FUNCTION - A method is provided comprising: enumerating a group of available virtual functions corresponding to the physical function; mapping the group of available virtual functions to a non-transparent port of the switch by creating a copy of a configuration space for the physical function while assigning unique vendor and device identifications for different classes of devices, wherein the mapping creates a pseudo physical function exposing a subset of the SR-IOV capability from the configuration space for the physical function; receiving a request to access the physical function from the single host; and providing the pseudo physical function to the single host for loading on the single host, in response to the receiving of the request, wherein the pseudo physical function is designed to call management functions of the single host to enable the group of available virtual functions in a local hierarchy of the single host. | 06-28-2012 |
20120173945 | PARALLEL PACKETIZED INTERCONNECT WITH SIMPLIFIED DATA LINK LAYER - In a first embodiment of the present invention, a method for error-correcting in a parallel interconnect transmitting device is provided, the method comprising: detecting a frame transition in a transmission from the transmitting device to a parallel interconnect receiving device; tracking time between the frame transition and a transition of a response signal corresponding to the frame transition received from the receiving device; detecting an error in the transmission; and restarting a portion of the transmission in response to the error, wherein the size of the portion of the transmission to restart is based upon the tracked time between the frame transition and the transition of a response signal corresponding to the frame transition. | 07-05-2012 |
20130010636 | THREE DIMENSIONAL FAT TREE NETWORKS - In a first embodiment of the present invention, a non-blocking switch fabric is provided comprising: a first set of intra-domain switches; a second set of intra-domain switches; a set of inter-domain switches located centrally between the first set of intra-domain switches and the second set of intra-domain switches, wherein each of the ports of each of the inter-domain switches is connected to an intra-domain switch from the first or second set of intra-domain switches. | 01-10-2013 |
20130024595 | PCI EXPRESS SWITCH WITH LOGICAL DEVICE CAPABILITY - A PCIe switch implements a logical device for use by connected host systems. The logical device is created by logical device enabling software running on a host management system. The logical device is able to consolidate one or more physical devices or may be entirely software-based. Commands from the connected host are processed in the command and response queues in the host and are also reflected in shadow queues stored in the management system. A DMA engine associated with the connected host is set up to automatically trigger on queues in the connected (local) host. Commands are sent to the physical devices to complete the work and a completion signal is sent to the management software and a response to the work is sent directly to the connected host, which is not aware that the logical device is non-existent and is implemented by software in the management system. | 01-24-2013 |
20140122765 | METHOD AND APPARATUS FOR SECURING AND SEGREGATING HOST TO HOST MESSAGING ON PCIE FABRIC - A PCIe fabric includes at least one PCIe switch. The fabric may be used to connect multiple hosts. The PCIe switch implements security and segregation measures for host-to-host message communication. A management entity defines a Virtual PCIe Fabric ID (VPFID). The VPFID is used to enforce security and segregation. The fabric ID may be extended to be used in switch fabrics with other point-to-point protocols. | 05-01-2014 |
20150019789 | METHOD AND APPARATUS FOR SECURING AND SEGREGATING HOST TO HOST MESSAGING ON PCIE FABRIC - A PCIe fabric includes at least one PCIe switch. The fabric may be used to connect multiple hosts. The PCIe switch implements security and segregation measures for host-to-host message communication. A management entity defines a Virtual PCIe Fabric ID (VPFID). The VPFID is used to enforce security and segregation. The fabric ID may be extended to be used in switch fabrics with other point-to-point protocols. | 01-15-2015 |
Jack Regula, Durham, NC US
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20140237156 | MULTI-PATH ID ROUTING IN A PCIE EXPRESS FABRIC ENVIRONMENT - PCIe is a point-to-point protocol. A PCIe switch fabric has multi-path routing supported by adding an ID routing prefix to a packet entering the switch fabric. The routing is converted within the switch fabric from address routing to ID routing, where the ID is within a Global Space of the switch fabric. Rules are provided to select optimum routes for packets within the switch fabric, including rules for ordered traffic, unordered traffic, and for utilizing congestion feedback. In one implementation a destination lookup table is used to define the ID routing prefix for an incoming packet. The ID routing prefix may be removed at a destination host port of the switch fabric. | 08-21-2014 |
Jay Regula, Miramar, FL US
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20080243959 | Apparatus and method for backing up computer files - An apparatus and method for backing up computer files comprising a portable housing, nonvolatile memory within the housing, an interface on the housing for communication between the nonvolatile memory and the computing device, and a software application in the nonvolatile memory. Using the software application, files are designated on the computing device for backing up. Copies of the designated files are made by the application and stored in the nonvolatile memory. The software application may also be used to designate backed up files in the nonvolatile memory for restoration on the computing device. Copies of the designated files are made by the application and restored on the computing device. | 10-02-2008 |
Jeorg Thomas Regula, Munchen DE
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20150064735 | METHOD FOR THE DETERMINATION OF SEQUENCE VARIANTS OF POLYPEPTIDES - The current invention is directed to a method for determining amino acid sequence mutations in a produced polypeptide, comprising the following steps of a) providing a sample of a produced polypeptide, b) incubating the polypeptide in the sample with a protease, c) performing a two dimensional analysis using reversed phase chromatography coupled with a high resolution mass spectroscopy (FT-ICR/FT-orbitrap) and MS/MS analysis of the amino acid sequence fragments of the peptides, d) data evaluation by comparing the LC-MS data sets obtained for the samples side by side with the data set of a reference sample, by searching for differences in the signal intensities at given retention times and by evaluation of differential signals with respect to amino acid sequence mutations. The reference sample for data evaluation (d) can be either a well characterized standard or one of the samples to be analyzed. | 03-05-2015 |
Jeorg Thomas Regula, Muenchen DE
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20120322093 | METHOD FOR THE DETERMINATION OF SEQUENCE VARIANTS OF POLYPEPTIDES - The current invention is directed to a method for determining amino acid sequence mutations in a produced polypeptide, comprising the following steps of a) providing a sample of a produced polypeptide, b) incubating the polypeptide in the sample with a protease, c) performing a two dimensional analysis using reversed phase chromatography coupled with a high resolution mass spectroscopy (FT-ICR/FT-orbitrap) and MS/MS analysis of the amino acid sequence fragments of the peptides, d) data evaluation by comparing the LC-MS data sets obtained for the samples side by side with the data set of a reference sample, by searching for differences in the signal intensities at given retention times and by evaluation of differential signals with respect to amino acid sequence mutations. The reference sample for data evaluation (d) can be either a well characterized standard or one of the samples to be analyzed. | 12-20-2012 |
Joerg Regula, Muenchen DE
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20110009317 | CONJUGATES OF INSULIN-LIKE GROWTH FACTOR-1 AND POLY(ETHYLENE GLYCOL) - A conjugate consisting of an insulin-like growth factor-1 (IGF-I) variant and one or two poly(ethylene glycol) group(s), characterized in that said IGF-I variant has an amino acid alteration at up to three amino acid positions 27, 37, 65, 68 of the wild-type IGF-I amino acid sequence so that one or two of said amino acids is/are lysine and amino acid 27 is a polar amino acid but not lysine, is conjugated via the primary amino group(s) of said lysine(s) and said poly(ethylene glycol) group(s) have an overall molecular weight of from 20 to 100 kDa is disclosed. This conjugate is useful for the treatment of neurodegenerative disorders like Alzheimer's Disease. | 01-13-2011 |
20120322732 | CONJUGATES OF INSULIN-LIKE GROWTH FACTOR-1 AND POLY(ETHYLENE GLYCOL) - A conjugate consisting of an insulin-like growth factor-1 (IGF-I) variant and one or two poly(ethylene glycol) group(s), characterized in that said IGF-I variant has an amino acid alteration at up to three amino acid positions 27, 37, 65, 68 of the wild-type IGF-I amino acid sequence so that one or two of said amino acids is/are lysine and amino acid 27 is a polar amino acid but not lysine, is conjugated via the primary amino group(s) of said lysine(s) and said poly(ethylene glycol) group(s) have an overall molecular weight of from 20 to 100 kDa is disclosed. This conjugate is useful for the treatment of neurodegenerative disorders like Alzheimer's Disease. | 12-20-2012 |
Joerg Thomas Regula, Muenc Hen DE
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20100261216 | STABILITY TESTING OF ANTIBODIES - Antibodies are biological macromolecules which may be subject to modification and degradation processes. A new LC/MS-based method for separating and characterizing antibody-specific degradation products is described in the present application which comprises an enzymatic digestion step to cleave the heavy chain using the enzyme IdeS. | 10-14-2010 |
Joerg Thomas Regula, Muenchuen DE
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20110293613 | BISPECIFIC ANTIBODIES - The present invention relates to bispecific antibodies, methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof. | 12-01-2011 |
Joseph C Regula, Broadview Heights, OH US
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20130192162 | CONVERTIBLE FLOOR MAT APPARATUS AND METHOD - A floor mat having a first surface, and a second surface; and a friction-increasing element removably affixed to the second surface. | 08-01-2013 |
20140275330 | DUAL PURPOSE COATING - A protective floor covering or desk pad comprising a body having an upper and lower planar surface and a copolymer resin coating on the lower planar surface. | 09-18-2014 |
20150065605 | DUAL PURPOSE COATING - A protective floor covering or desk pad comprising a body having an upper and lower planar surface and a copolymer resin coating on the lower planar surface. | 03-05-2015 |
Tiberius Regula, Bad Aibling DE
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20100116717 | METHOD FOR THE DESULFURIZATION OF FUELS AND HIGHLY ACTIVE NICKEL CARRIER CATALYST BASED ON ALUMINUM OXIDE SUITABLE FOR SAID METHOD - A highly active nickel carrier catalyst based on aluminium oxide has a nickel content of approximately 20 to 70 wt.-% (as Ni) and optionally comprises a bonding agent and optionally a promoter, selected from the compounds of Mg, Ti, Pb, Pt, Ba, Ca and/or Cu, wherein the size of the Ni crystallites in the reduced state is in the range of approximately 3.5 to 4.5 nm and the distortion factor of the Ni crystallites is approximately 2 to 5%. In a method for the reduction of the content of sulphur compounds in hydrocarbon-based fuels by selective adsorption of the sulphur compounds on a nickel catalyst, a nickel catalyst based on aluminium oxide is used, particularly the nickel catalyst described above. A nickel catalyst based on aluminium oxide may be used for reducing the sulphur compound content in hydrocarbon-based fuels by selective adsorption of the sulphur compounds on said catalyst and/or for the hydrogenation of aromatic compounds. | 05-13-2010 |