Reem
Reem Al-Hejailan, Riyadh SA
Patent application number | Description | Published |
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20140075585 | Tetraspanin CD82 as a Diagnostic and/or Therapeutic Module for Xenograft Recognition and/or Rejection - The present invention relates to CD82 polypeptides of the mammalian tetraspanin CD82 protein family for use in the diagnosis, prevention and/or treatment of xenograft recognition and/or rejection. The present invention furthermore relates to CD82 knockout and transgenic animals and their cells, tissues and organs. The present invention furthermore relates to antibodies against a CD82 polypeptide, pharmaceutical compositions comprising at least one inhibitor of a CD82 polypeptide or comprising cells, tissues and organs of animals in which the CD82 level, expression and/or activity is modified, and their use in the diagnosis, prevention and/or treatment of xenograft recognition and/or rejection. The present invention furthermore relates to methods of diagnosing xenograft recognition and/or rejection and methods for the prevention and/or treatment of xenograft recognition and/or rejection as well as methods of xenotransplantation. | 03-13-2014 |
Reem Almarzouqi, Al Ain AE
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20120210820 | LOWER EXTREMITY VEHICLE NAVIGATION CONTROL SYSTEM - A lower extremity vehicle navigation control system for driving a vehicle with one or more lower extremities is disclosed. The system may include a steering engagement surface, a brake engagement surface, and an acceleration control engagement surface positioned between a driver's seat and a vehicle floor forming a driver's compartment such that a driver may use his lower extremity to steer the vehicle, to brake and to accelerate. Each of the engagement surfaces may be in relative proximity to each other such that a driver may easily move his lower extremity between contact with each of the engagement surfaces. The system may also include gear shifting arm and a foot activated ignition system, both of which may be operable by one or more lower extremities of a driver of a vehicle. | 08-23-2012 |
Reem Al-Olaby, Cairo EG
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20150328329 | LIGANDS THAT TARGET HCV-E2 BINDING SITES ON CD81 AND THERAPEUTIC METHODS USING THEM - Ligands that target the HCV-E2 binding site and methods of making and using them. A series of ligand binding sites on the large extracellular loop of the open conformation of CD81 have been identified. Several important sites were located in regions identified by mutational studies to be the site of E2 binding. Ligands that recognize these sites were identified. Linking together two or three ligands that bind with low or moderate affinities to different structurally unique sites on a target protein were used to generate small molecule ligand conjugates that exhibit very high affinities to their CD81 targets. Hybrid ligand molecules were also designed using fragment-based drug design methods to generate analogs of the ligands that bind more tightly to the protein than the parent compounds. Identification and design of groups of compounds that bind to CD81 for use as therapeutics for treating patients infected by Hepatitis C virus and other viruses that interact with CD81. By binding to CD81, these molecules can block 1) HCV and other viral entry into cells (infection), 2) inflammatory responses caused by HCV and other viral infections, and 3) the induction of HCV associated cancers. | 11-19-2015 |
Reem Bensimhon, Tel Aviv IL
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20120192055 | DISTRIBUTED DOCUMENT CO-AUTHORING AND PROCESSING - A method and a device are disclosed including plug-in software components that are integrated with document processing software suites. The plug-in software components provide a set of integrated interfaces for collaborative document processing in conjunction with multiple remote file, data, and application service providers. The set of interfaces enable coauthoring a document, document merging, discovering and displaying context-sensitive metadata on a software dashboard based on permissions associated with the metadata and/or a client computing device, caching, symmetric distributed document merge with the multiple service providers, and integrated search and insertion of multimedia data in documents, among others. The documents typically include, but are not limited to formatted text documents, spreadsheet documents, and slide presentation documents. | 07-26-2012 |
20120192064 | DISTRIBUTED DOCUMENT PROCESSING AND MANAGEMENT - A method and a device are disclosed including plug-in software components that are integrated with document processing software suites. The plug-in software components provide a set of integrated interfaces for collaborative document processing in conjunction with multiple remote file, data, and application service providers. The set of interfaces enable coauthoring a document, document merging, displaying context-sensitive metadata on a software dashboard, caching, symmetric distributed document merge with the multiple service providers, and integrated search and insertion of multimedia data in documents, among others. The documents typically include, but are not limited to formatted text documents, spreadsheet documents, and slide presentation documents. | 07-26-2012 |
20150331841 | DISTRIBUTED DOCUMENT CO-AUTHORING AND PROCESSING - A method and a device are disclosed including plug-in software components that are integrated with document processing software suites. The plug-in software components provide a set of integrated interfaces for collaborative document processing in conjunction with multiple remote file, data, and application service providers. The set of interfaces enable coauthoring a document, document merging, discovering and displaying context-sensitive metadata on a software dashboard based on permissions associated with the metadata and/or a client computing device, caching, symmetric distributed document merge with the multiple service providers, and integrated search and insertion of multimedia data in documents, among others. The documents typically include, but are not limited to formatted text documents, spreadsheet documents, and slide presentation documents. | 11-19-2015 |
Reem Miari, Sakhnin IL
Patent application number | Description | Published |
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20100297083 | Polynucleotides and Polypeptide of Human KV1.3, Compositions Comprising Same and Methods of Using Same - An isolated polypeptide comprising, contiguously, a first amino acid sequence being at least 90% homologous to amino acid coordinates 1-398 of SEQ ID NO: 2, a tryptophan residue and a second amino acid sequence being at least 90% homologous to amino acid coordinates 400-523 of SEQ ID NO: 2. Also provided are polynucleotide sequences encoding this polypeptide and uses of same in the treatment of medical conditions associated with ion channel insufficiency. | 11-25-2010 |
20150118187 | MICRO-ORGANS PROVIDING SUSTAINED DELIVERY OF A THERAPEUTIC POLYPEPTIDE AND METHODS OF USE THEREOF - The present invention is directed to long-lasting therapeutic formulations and their methods of use wherein the formulation comprises a genetically modified micro-organ that comprises a nucleic acid sequence operably linked to one or more regulatory sequences. The present invention is further directed to methods providing sustained expression of therapeutic polypeptides and prolonged therapeutic effects, such as erythropoietin and interferon. | 04-30-2015 |
Reem Smoum, Jerusalem IL
Patent application number | Description | Published |
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20110046222 | FATTY ACID AMIDES AND USES THEREOF - Provided are fatty acid amides of amino acids, uses thereof and pharmaceutical compositions including them. | 02-24-2011 |