Patent application number | Description | Published |
20090209593 | NOVEL ANTIBACTERIAL AGENTS - This invention relates to novel macrolides, to the preparation of novel macrolides, to the use of such novel macrolides for preventing, treating, or ameliorating various conditions, and to the use of such novel macrolides as antibacterial agents. | 08-20-2009 |
20100210543 | Aldehyde-Tagged Protein-Based Drug Carriers and Methods of Use - The disclosure provides aldehyde-tagged protein carriers that can be covalently and site-specifically bound to drug to provide a drug-containing scaffold. The invention also encompasses methods of production of such drug-containing scaffolds and intermediates, as well as methods of use. | 08-19-2010 |
20120183566 | Aldehyde-Tagged Immunoglobulin Polypeptides and Methods of Use Thereof - The present disclosure provides aldehyde-tagged immunoglobulin (Ig) polypeptides that can be converted by a formylglycine-generating enzyme to produce a 2-formylglycine (FGly)-modified Ig polypeptide. An FGly-modified Ig polypeptide can be covalently and site-specifically bound to a moiety of interest to provide an Ig conjugate. The disclosure also encompasses methods of production of such aldehyde-tagged Ig polypeptides, FGly-modified Ig polypeptides, and Ig conjugates, as well as methods of use of same. | 07-19-2012 |