Péter
Péter Ács, Pecs HU
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20110098255 | COMBINATION OF A PARP INHIBITOR AND AN AKT KINASE ACTIVATING COMPOUND - The primary subject of the invention is the use of a PARP inhibitor and an Akt kinase activating compound in combination in the treatment of pathological conditions related to PARP activation and/or that could benefit from Akt activation. A further subject of the invention is the use of a PARP inhibitor and an Akt kinase activating compound in combination for the preparation of pharmaceutical composition or kit for the treatment of a pathological condition related to PARP activation. The invention also relates to pharmaceutical composition, which contains a PARP-inhibitor and an Akt kinase activating compound together with auxiliaries generally used in pharmacy. | 04-28-2011 |
Péter Ács, Pecs HU
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20110098255 | COMBINATION OF A PARP INHIBITOR AND AN AKT KINASE ACTIVATING COMPOUND - The primary subject of the invention is the use of a PARP inhibitor and an Akt kinase activating compound in combination in the treatment of pathological conditions related to PARP activation and/or that could benefit from Akt activation. A further subject of the invention is the use of a PARP inhibitor and an Akt kinase activating compound in combination for the preparation of pharmaceutical composition or kit for the treatment of a pathological condition related to PARP activation. The invention also relates to pharmaceutical composition, which contains a PARP-inhibitor and an Akt kinase activating compound together with auxiliaries generally used in pharmacy. | 04-28-2011 |
Péter ArÁnyi, Budapest HU
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20110118305 | COMPOUNDS - Heterocyclic amides useful as inhibitors of dipeptylpeptidase-IV (DPP-IV) enzyme, process for the preparation thereof and intermediates therefore. | 05-19-2011 |
Péter Bagossi, Debrecen HU
Péter Banhegyi, Budapest HU
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20090298842 | Novel therapeutic targets for the treatment of mycobacterial infections and compounds useful therefor - Described herein is the discovery that certain mycobacterial serine/threonine protein kinases, particularly protein kinase G (PknG), are effective therapeutic targets for the treatment of mycobacterial infections. Furthermore, the present application refers to the use of mycobacterial serine/threonine protein kinases for developing methods for detection and determination of these kinases for recognizing and monitoring diseases and for controlling therapy of diseases. Additionally disclosed are novel 4,5,6,7-tetrahydrobenzo[b]thiophene compounds, benzo(g)quinoxaline compounds, and pharmaceutically acceptable salts thereof, and methods of using such compounds and salts thereof for the prophylaxis and/or treatment of virally and/or bacterially induced infections, particularly mycobacteria-induced infections, including opportunistic infections, as well as pharmaceutical compositions containing at least one 4,5,6,7-tetrahydrobenzo[b]thiophene compound and/or benzo(g)quinoxaline compound and/or pharmaceutically acceptable salts thereof in a pharmaceutically acceptable carrier. | 12-03-2009 |
Péter Benkö, Budapest HU
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20110078163 | METHOD AND SYSTEM FOR NETWORK FAULT MANAGEMENT - Methods of processing record data are presented, together with a Central Management Node for processing record data, and Management Subsystem DataBases for providing a record data set and matching record data. Triggered by service related network fault event, a key table comprising at least one key type is determined, based on a focus target record and related to the network fault event is determined, which key table is used in the step matching the at least one key with record data sets in determined Management Subsystem Databases. Matched results are merged, whereafter a service performance indicator may be determined, based on which a multi-layer water flow analysis of subsystem specific performance related indicators can be obtained. This analysis may be successfully used to reveal the location of the service related network fault. | 03-31-2011 |
20110093592 | IMS PERFORMANCE MONITORING - A method and apparatus enabling performance monitoring in packet-switched IP networks such as those configured according to an IP multimedia subsystem, IMS, architecture. Performance is monitored by reconstructing selected control signaling sequences. The control signaling sequences, which are typically executed according a signaling protocol such as the Session Initiation Protocol, SIP, are reconstructed by parsing the contents of monitoring request headers configured, modified, and attached to control messages according to the present invention. The header includes at least an IMS monitoring ID field ( | 04-21-2011 |
20110173165 | MANAGEMENT OF PERFORMANCE DATA - A method of handling performance data comprising a set of events is described. An event record for each event is stored as a set of blocks, each block containing one or more attributes of the event. The storage space occupied by each event record in is then reduced in discrete steps, each step including a reduction process that reduces the size of one of the set of blocks. This enables the provision of intermediate records between events and counters so that new event records contain complete details of their event, older event records contain less information, and even older event records may contain only high-level (counter) information. | 07-14-2011 |
20120275331 | Random Data Stream Sampling - There is provided a method of sampling data elements from a data stream for subsequent analysis, the data stream comprising a plurality of data elements, wherein each data element has a respective unique quasi-random identifier determined from a set of identifiers, the method comprising selecting data elements from the data stream whose identifiers are within a first element selection range to give a set of selected data elements, the first element selection range being a subset of the set of identifiers; wherein, once the set of selected data elements comprises a predetermined number of data elements, the method further comprises: determining a second element selection range as a proper subset of the first element selection range; discarding data elements from the set of selected data elements whose identifiers are not within the second element selection range; and selecting at least one further data element from the data stream whose identifier is within the second element selection range for the set of selected data elements. | 11-01-2012 |
Péter Benkö, Budapest HU
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20100156622 | POLL-BASED ALARM HANDLING SYSTEM AND METHOD - A system and method of handling poll-based alarms. The method begins by detecting a high-priority problem in a network. Next, network elements in the network related to the high-priority problem are mapped. The mapping step includes grouping network elements into focus groups wherein each focus group includes network elements having the same alarm. The mapped network elements are then polled for alarms. The polled alarms of the network elements are then correlated and processed. | 06-24-2010 |
20110078163 | METHOD AND SYSTEM FOR NETWORK FAULT MANAGEMENT - Methods of processing record data are presented, together with a Central Management Node for processing record data, and Management Subsystem DataBases for providing a record data set and matching record data. Triggered by service related network fault event, a key table comprising at least one key type is determined, based on a focus target record and related to the network fault event is determined, which key table is used in the step matching the at least one key with record data sets in determined Management Subsystem Databases. Matched results are merged, whereafter a service performance indicator may be determined, based on which a multi-layer water flow analysis of subsystem specific performance related indicators can be obtained. This analysis may be successfully used to reveal the location of the service related network fault. | 03-31-2011 |
20110093592 | IMS PERFORMANCE MONITORING - A method and apparatus enabling performance monitoring in packet-switched IP networks such as those configured according to an IP multimedia subsystem, IMS, architecture. Performance is monitored by reconstructing selected control signaling sequences. The control signaling sequences, which are typically executed according a signaling protocol such as the Session Initiation Protocol, SIP, are reconstructed by parsing the contents of monitoring request headers configured, modified, and attached to control messages according to the present invention. The header includes at least an IMS monitoring ID field ( | 04-21-2011 |
20110202593 | FOCUSED SAMPLING OF TERMINAL REPORTS IN A WIRELESS COMMUNICATION NETWORK - A performance management system and method are described herein that can control which client terminal(s) (e.g., mobile terminal(s)) are to provide Quality of Experience, QoE, report(s) and also control a level of detail for the requested QoE report(s). | 08-18-2011 |
Péter Ferdinandy, Szeged HU
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20100087362 | USE OF BIGLYCAN OR ENHANCERS OF BIGLYCAN ACTIVITY IN THE PREPARATION OF PHARMACEUTICAL COMPOSITIONS - The present invention relates to the use of biglycan or enhancers of biglycan activity in the preparation of pharmaceutical compositions having anti-atherosclerotic and anti-ischemic effect, and to the use of them in methods for preventing and treating the atherosclerotic and ischemid (e.g. cardiac) diseases. The invention also relates to screening methods by which biglycan or enhancers of biglycan activity can be identified. | 04-08-2010 |
20130303572 | NOVEL INHIBITORS OF MATRIX METALLOPROTEINASES - Compounds of general formula (I), salts or solvates thereof and pharmaceutical compositions containing same: | 11-14-2013 |
Péter Ferdinandy, Szeged HU
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20100087362 | USE OF BIGLYCAN OR ENHANCERS OF BIGLYCAN ACTIVITY IN THE PREPARATION OF PHARMACEUTICAL COMPOSITIONS - The present invention relates to the use of biglycan or enhancers of biglycan activity in the preparation of pharmaceutical compositions having anti-atherosclerotic and anti-ischemic effect, and to the use of them in methods for preventing and treating the atherosclerotic and ischemid (e.g. cardiac) diseases. The invention also relates to screening methods by which biglycan or enhancers of biglycan activity can be identified. | 04-08-2010 |
20130303572 | NOVEL INHIBITORS OF MATRIX METALLOPROTEINASES - Compounds of general formula (I), salts or solvates thereof and pharmaceutical compositions containing same: | 11-14-2013 |
Péter HolobrÁdi, Budaors HU
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20120217794 | TRACTION-SLIP CONTROLLED BRAKE SYSTEM OF A MOTOR VEHICLE APPROACHING STOPS - A traction-slip controlled vehicle brake system having a) a service-brake valve, which generates an actuation-dependent pressure at an outlet port; b) a valve device, in a first operating position, establishes a connection from a pressure medium reserve and, in a second operating position, from a 2/2 solenoid valve to a brake actuator; c) the solenoid valve being connected to the outlet port of the service-brake valve and to a first connection of the valve device. The solenoid valve and valve device are controllable by a control device to d) allow the solenoid valve to switch open and the valve device to switch to the first operating position for traction-slip control; e) and a brake pressure generated at a predetermined level based on the pressure medium from the pressure medium supply in the brake actuator; the solenoid valve being switched closed and the valve device to the first operating position. | 08-30-2012 |
Péter Klein, Budapest HU
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20110106223 | LIGHT THERAPY SKIN CARE DEVICE - The invention is a light therapy skin care device that includes light sources in a layout that is configured for lighting of human body's given skin surfaces (B) or its parts. Among light sources, there is a UV light emitting and a UV-free light emitting device, the light sources are connected to a controlled driver unit. The light sources are divided in two groups, where in the first group there are ( | 05-05-2011 |
Péter Klein, Budapest HU
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20110106223 | LIGHT THERAPY SKIN CARE DEVICE - The invention is a light therapy skin care device that includes light sources in a layout that is configured for lighting of human body's given skin surfaces (B) or its parts. Among light sources, there is a UV light emitting and a UV-free light emitting device, the light sources are connected to a controlled driver unit. The light sources are divided in two groups, where in the first group there are ( | 05-05-2011 |
Péter Klivényi, Szeged HU
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20130172346 | USE OF KYNURENIC ACID AMIDE DERIVATIVES FOR THE TREATMENT OF HUNTINGTON'S DISEASE - The invention is directed to kynurenic acid analogues and pharmaceutically acceptable salts thereof and pharmaceutical compositions containing said compounds for treating the symptoms of Huntington's disease and preventing the development of the symptoms. | 07-04-2013 |
Péter Krajcsi, Budapest HU
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20100021927 | CHOLESTEROL LOADED INSECT CELL MEMBRANES AS TEST SYSTEMS FOR ABC TRANSPORTER PROTEINS - The invention provides for a novel cholesterol loaded insect cell membrane preparation having an increased cholesterol level as compared to physiological cholesterol levels of insect cell membranes or to control insect cell membrane preparations without cholesterol loading, wherein said cholesterol loaded membrane preparation comprises an ABC transporter protein having an increased substrate transport activity due to increased cholesterol level of the membrane. The invention also relates to reagent kits comprising the preparations of the invention. The invention also relates to methods for manufacturing said preparations and methods for measuring any type of activity of the ABC transporters present in the cholesterol loaded membranes as well as studying or testing compounds and interaction of compounds and ABC transporters, in this assay systems. The invention also provides for a test system useful for testing whether ABC transporter proteins can be activated by cholesterol in an insect cell membrane. | 01-28-2010 |
Péter Krajcsi, Budapest HU
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20100021927 | CHOLESTEROL LOADED INSECT CELL MEMBRANES AS TEST SYSTEMS FOR ABC TRANSPORTER PROTEINS - The invention provides for a novel cholesterol loaded insect cell membrane preparation having an increased cholesterol level as compared to physiological cholesterol levels of insect cell membranes or to control insect cell membrane preparations without cholesterol loading, wherein said cholesterol loaded membrane preparation comprises an ABC transporter protein having an increased substrate transport activity due to increased cholesterol level of the membrane. The invention also relates to reagent kits comprising the preparations of the invention. The invention also relates to methods for manufacturing said preparations and methods for measuring any type of activity of the ABC transporters present in the cholesterol loaded membranes as well as studying or testing compounds and interaction of compounds and ABC transporters, in this assay systems. The invention also provides for a test system useful for testing whether ABC transporter proteins can be activated by cholesterol in an insect cell membrane. | 01-28-2010 |
Péter Literati Nagy, Budapest HU
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20090214677 | Pharmaceutical Composition Containing an Extract of a Solidago Species - An extract of a part of a | 08-27-2009 |
Péter Mátyus, Budapest, HU
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20110263567 | COMPOUNDS FOR INHIBITING SEMICARBAZIDE-SENSITIVE AMINE OXIDASE (SSAO) / VASCULAR ADHESION PROTEIN-1 (VAP-1) AND USES THEREOF FOR TREATMENT AND PREVENTION OF DISEASES - The present invention relates to compounds of general formula (i) having an oxime moiety or a pharmaceutically acceptable salt, hydrate or solvate thereof and its use for inhibiting semicarbazide-sensitive amine oxidase (SSAO), also known as vascular adhesion protein-1 (VAP-1), a pharmaceutical composition comprising the compound or a salt, hydrate or solvate thereof as an active ingredient, a method for the prevention or the treatment of a SSAO/VAP-1 related disease, said diseases including acute or chronic inflammatory diseases, diseases related to carbohydrate metabolism, diabetes-associated complications, diabetic retinopathy and macular oedema, diseases related to adipocyte or smooth muscle dysfunctions, neurodegenerative diseases and vascular diseases. | 10-27-2011 |
Péter Németh, Pécs HU
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20110136140 | DIAGNOSIS OF SYSTEMIC DISEASES - It has been found that the pattern of recognized topo I epitopes is different between dcSSc, IcSSc and SLE patients. Fragment F4 (amino acid (AA) 450-600) was recognized by all patients tested. Fragment F1 (AA 5-30) and Fragment F8 (AA 350-400) represent characteristic epitopes for dcSSc and SLE, respectively. The invention relates to diagnostic uses and methods as well as kits for use in diagnosis. | 06-09-2011 |
Péter Onódy, Hungary HU
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20130083868 | COMBINED COMPLEX REAL MODE DELTA-SIGMA ADC - A delta-sigma analog-to-digital converter (ADC) is disclosed. In one embodiment, the delta-sigma ADC includes a dual mode resonator and a plurality of switches. The delta-sigma ADC is configured to operate in a real modulation mode or a complex modulation mode based on settings of the plurality of switches. | 04-04-2013 |
Péter Onódy, Budapest HU
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20130082720 | RC CALIBRATION USING CHOPPING - A method and apparatus for determining an RC (resistive-capacitive) time constant is disclosed. In one embodiment, a method comprises determining a first period of oscillation when an oscillator is operating in a first configuration. The method further the method further comprises determining a second period of oscillation when the oscillator is operating in a second configuration. A measurement circuit is configured to determine a resistive-capacitive (RC) time constant of the oscillator by determining a mean of the first and second periods. | 04-04-2013 |
Péter Slégel, Budapest HU
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20130030183 | PROCESS FOR PREPARING A PHARMACEUTICAL COMPOUND - The object of the present invention is a one-pot process for preparing the 2-acetoxy-5-(2-fluoro-α-cyclopropyl-carbonyl-benzyl)-4,5,6,7-tetrahydro-4H-tieno[3,2-c]-pyridine (prasugrel) of the formula (I) by reacting the 5,6,7,7a-tetrahydro-4H-tieno[3,2-c]-pyridine-2-on of the formula (II) with 2-bromo-1-cyclopropyl-2-(2-fluorophenyl)-etanone of the formula (III) or with 2-chloro-1-cyclopropyl-2-(2-fluorphenyl)-etanone of the formula (IIIa) and acetylating of the formed compound of the formula (IV), wherein the reaction is carried out in the presence of an organic base with an acetylation agent without isolating the compound of the formula (IV). The coupling and acetylation are carried out in the presence of the same organic base such as triethylamine, N,N-diisopropyl-ethylamine or pyridine. At the end of the process the prasugrel of the formula (I) is purified by recrystallization from an organic solvent or a mixture of solvents. | 01-31-2013 |
Péter Soldos, Budapest HU
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20130123084 | EQUIPMENT FOR IMPROVING PHYSICAL FITNESS - The invention discloses an equipment for improving physical fitness, whose primary aspect is muscle strengthening. Another objective of the invention, besides maximizing muscle development, is to minimize the risk of injury during and after practices. The invention has a comfortable, tailor-made design shell ( | 05-16-2013 |
Péter Szakály, Kormend HU
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20120167671 | METHOD AND APPARATUS FOR TESTING TRANSDERMAL MEDICAMENTS - The invention relates to an apparatus and method for testing transdermal medicaments, wherein the sample tested in a membrane penetration cell resides in the open sample compartment of said cell and is exposed to environmental factors such as temperature, air flow, light and air humidity during testing the absorption and penetration. | 07-05-2012 |
Péter Szegõ, Budapest HU
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20130195974 | PH-DEPENDENT GRADUAL RELEASE PHARMACEUTICAL COMPOSITION - The invention concerns a pH-dependent gradual sustained release composition for increasing the pH in the upper part of the small intestines. Particles of the composition are provided with a multilayer polymer coating of specific structure which ensures the gradual release of the active agent in the range of pH 4.5 to 5.5. A process for preparing said composition is also claimed. | 08-01-2013 |
Péter Széll, Budapest HU
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20110125381 | BRAKE SYSTEM AND METHOD FOR CONTROLLING A VEHICLE BRAKE - The brake system for motor vehicles has a brake pedal unit having a sensor, which has an intelligence of its own in the form of an electronic processing unit, which directly calculates actuating signals for brake actuators. Furthermore, the brake system has a central electronic control unit, which ascertains actuating signals for the actuators on the basis of an analog or digital signal of the mentioned sensor or of an additional sensor. The actuators have an intelligence of their own in the form of an electronic processing unit, which verifies whether the actuating signal coming from the central electronic control unit is valid. If this is the case, then the actuators are controlled by this signal, otherwise on the basis of the actuating signal calculated by the sensor. | 05-26-2011 |
Péter Szentiványi, Szeged HU
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20120260994 | METHOD AND APPARATUS FOR HANDLING GASES - The invention relates to an apparatus and a method for handling gases, the apparatus comprising an inlet gas duct ( | 10-18-2012 |
Péter Szolgay, Budapest HU
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20100110026 | TACTILE SENSOR AND SIGNAL PROCESSING METHOD FOR A TACTILE SENSOR - The invention is a signal processing method for a tactile sensor, said tactile sensor having a tactile surface and elementary sensors ( | 05-06-2010 |
Péter Szolgay, Budapest HU
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20100110026 | TACTILE SENSOR AND SIGNAL PROCESSING METHOD FOR A TACTILE SENSOR - The invention is a signal processing method for a tactile sensor, said tactile sensor having a tactile surface and elementary sensors ( | 05-06-2010 |
Péter Teleki, Dunaujvaros HU
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20130070883 | METHOD OF UTILIZING NUCLEAR REACTIONS OF NEUTRONS TO PRODUCE PRIMARILY LANTHANIDES AND/OR PLATINUM METALS - The method according to the invention is accomplished via neutrons ( | 03-21-2013 |
Péter Tömör, Mougins Le Haut FR
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20120303955 | Security Association Management - A method and system for managing IPsec Security Associations in a Security Association Database (SADB) in an IP network is described. At a key management application, a domain extension header is inserted into a PF_KEY message containing instructions to a key engine unit. The domain extension header identifies a domain within the Security Association Database. The PF_KEY message is sent to the key engine unit, which carries out the instructions only for Security Associations in the domain of the Security Association Database indicated by the domain extension header. | 11-29-2012 |
Péter Tömör, Mougins Le Haut FR
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20120303955 | Security Association Management - A method and system for managing IPsec Security Associations in a Security Association Database (SADB) in an IP network is described. At a key management application, a domain extension header is inserted into a PF_KEY message containing instructions to a key engine unit. The domain extension header identifies a domain within the Security Association Database. The PF_KEY message is sent to the key engine unit, which carries out the instructions only for Security Associations in the domain of the Security Association Database indicated by the domain extension header. | 11-29-2012 |
Péter Tömpe, Budapest HU
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20090306117 | ROSUVASTATIN ZINC SALT - The present invention is related to rosuvastatin zinc salt of the Formula (I), process for preparation thereof and medicinal products containing said salt. Rosuvastatin zinc salt according to the present invention is prepared by reacting rosuvastatin with a zinc alcoholate, zinc enolate or an inorganic or organic zinc salt and isolating the thus obtained rosuvastatin zinc salt (2:1). | 12-10-2009 |
Péter Tömpe, Budapest HU
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20090306117 | ROSUVASTATIN ZINC SALT - The present invention is related to rosuvastatin zinc salt of the Formula (I), process for preparation thereof and medicinal products containing said salt. Rosuvastatin zinc salt according to the present invention is prepared by reacting rosuvastatin with a zinc alcoholate, zinc enolate or an inorganic or organic zinc salt and isolating the thus obtained rosuvastatin zinc salt (2:1). | 12-10-2009 |
Péter Tonka-Nagy, Budapest HU
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20130259904 | PRASUGREL CONTAINING QUICKLY RELEASED STABLE ORAL PHARMACEUTICAL COMPOSITIONS - Prasugrel containing quickly released stable oral pharmaceutical compositions containing micronized prasugrel base, and starch or a starch derivative, and processes for the preparation thereof, and the use thereof for treating atherothrombotic events of patients suffering from acute coronary syndrome in which patients were subjected to percutaneous coronary intervention. | 10-03-2013 |
Péter Tóth-Miklós, Budapest HU
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20110256523 | OPTICAL FLOW CYTOMETER AND METHOD OF INVESTIGATION - The present invention relates to a flow cytometer ( | 10-20-2011 |
Péter Vaderna, Budapest HU
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20110173165 | MANAGEMENT OF PERFORMANCE DATA - A method of handling performance data comprising a set of events is described. An event record for each event is stored as a set of blocks, each block containing one or more attributes of the event. The storage space occupied by each event record in is then reduced in discrete steps, each step including a reduction process that reduces the size of one of the set of blocks. This enables the provision of intermediate records between events and counters so that new event records contain complete details of their event, older event records contain less information, and even older event records may contain only high-level (counter) information. | 07-14-2011 |
Péter Várnai, Budapest HU
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20130195830 | PERORALLY APPLICABLE PREPARATION CONTAINING HISTAMINASE OF VEGETABLE ORIGIN, RESISTANT TO PEPSIN AND TRYPSIN AND A PROCESS FOR PRODUCING IT - The subject of the invention is a perorally applicable preparation of vegetable origin, resistant to pepsin and trypsin, based on histaminase, optionally for the use as an agent for improving digestion, reducing appetite or reducing body weight. The preparation of the invention is a pressed juice—which is optionally in lyophilized form—obtained from seedlings of pea ( | 08-01-2013 |