Patent application number | Description | Published |
20090048272 | PREPARATION OF PALIPERIDONE - Processes for preparing paliperidone. | 02-19-2009 |
20100261908 | PROCESSES FOR THE PREPARATION OF PRASUGREL , AND ITS SALTS AND POLYMORPHS - Processes for the preparation of prasugrel and its pharmaceutically acceptable salts thereof. Also disclosed are polymorphic forms of prasugrel hydrochloride and processes for their preparation. | 10-14-2010 |
20110201800 | AZACITIDINE PROCESS AND POLYMORPHS - Processes for preparing azacitidine. Further included are processes for the preparation of crystalline azacitidine crystalline Form (I) and mixtures of azacitidine crystalline Forms (I) and (II). | 08-18-2011 |
20110218360 | PREPARATION OF RASAGILINE AND SALTS THEREOF - The present invention relates to processes for the preparation of rasagiline mesylate. Also provided is rasagiline mesylate having 90 volume percent of the particles (D | 09-08-2011 |
20110224443 | PREPARATION OF FOSAMPRENAVIR CALCIUM - Process for preparation of fosamprenavir and its intermediate salts using novel phthalimide intermediates. | 09-15-2011 |
20130165662 | PREPARATION OF FEBUXOSTAT - Processes for preparing febuxostat. | 06-27-2013 |
20140155588 | AZACITIDINE PROCESS AND POLYMORPHS - Processes for preparing azacitidine. Further included are processes for the preparation of crystalline azacitidine crystalline Form I and mixtures of azacitidine crystalline Forms I and II. | 06-05-2014 |
Patent application number | Description | Published |
20080312536 | Oscillating Phased-Array Ultrasound Imaging Catheter System - A dynamic ultrasound image catheter includes a catheter body with an acoustic window on the distal end, an ultrasound phased array transducer assembly configured to rotate within the acoustic window through an angle of rotation, an acoustic coupling fluid filling a gap between the transducer array and the acoustic window, and a drive motor at the proximal end of the catheter body that is configured to rotate the transducer array. The drive motor may transmit a rotational force to the ultrasound phased array transducer by a drive wire or by tension wires coupled to drive spools. A system processor coupled to the drive motor controls rotation of the transducer array and estimates the angular orientation of the transducer array. By taking ultrasound images at increments through the angle of rotation, the dynamic ultrasound image catheter can obtain images spanning a volume which can be processed to generate three-dimensional composite images. | 12-18-2008 |
20090005679 | Ultrasound Image Processing To Render Three-Dimensional Images From Two-Dimensional Images - Methods for processing two-dimensional ultrasound images from an intracardiac ultrasound imaging catheter provide improved image quality and enable generating three-dimensional composite images of the heart. Two-dimensional ultrasound images are obtained and stored in conjunction with correlating information, such as time or an electrocardiogram. Images related to particular conditions or configurations of the heart can be processed in combination to reduce image noise and increase resolution. Images may be processed to recognize structure edges, and the location of structure edges used to generate cartoon rendered images of the structure. Structure locations may be averaged over several images to remove noise, distortions and blurring from movement. | 01-01-2009 |
20110251960 | Medical Data Encryption for Communication Over a Vulnerable System - A method for securing patient medical information for communication over a potentially vulnerable system includes separating patient's medical file into a demographics layer and a data layer, separately encrypting the demographic layer and data layer using different encryption keys, and providing servers in a communication and processing system with a decryption key for the layer processed by such server. Medical file data may be separated into more than two layers. Users accessing the system are authenticated using standard techniques. By separately encrypting different parts of a patient medical record, processing and communication of patient medical files by intermediary servers is enabled without risking disclosure of sensitive patient information if such servers are compromised. | 10-13-2011 |
20120022355 | Integrated electrophysiology and ultrasound imaging system - An integrated electrophysiology and ultrasound imaging system includes a workstation, electrophysiology processing circuits, a compact ultrasound imaging system having a combination of an isolation circuit, an ultrasound signal generator, and a beam former within a single unit. The integrated workstation provides a single control interface and data display for the electrophysiology and ultrasound imaging subsystems. Integrating the control of electrophysiology and ultrasound imaging equipment within a single workstation reduces clinician workload. | 01-26-2012 |
20120113108 | ULTRASOUND IMAGE PROCESSING TO RENDER THREE-DIMENSIONAL IMAGES FROM TWO-DIMENSIONAL IMAGES - Methods for processing two-dimensional ultrasound images from an intracardiac ultrasound imaging catheter provide improved image quality and enable generating three-dimensional composite images of the heart. Two-dimensional ultrasound images are obtained and stored in conjunction with correlating information, such as time or an electrocardiogram. Images related to particular conditions or configurations of the heart can be processed in combination to reduce image noise and increase resolution. Images may be processed to recognize structure edges, and the location of structure edges used to generate cartoon rendered images of the structure. Structure locations may be averaged over several images to remove noise, distortions and blurring from movement. | 05-10-2012 |
20130217997 | Method and apparatus for localizing an ultrasound catheter - An imaging system is provided with an ultrasound catheter and a controller coupled to the ultrasound catheter. The catheter includes a localizer sensor configured to generate positional information for the ultrasound catheter, and an imaging ultrasound sensor having a restricted field of view. The controller co-registers images from the imaging ultrasound sensor with positional information from the localizer sensor. | 08-22-2013 |
20140152653 | Ultrasound image processing to render three-dimensional images from two-dimensional images - Methods for processing two-dimensional ultrasound images from an intracardiac ultrasound imaging catheter provide improved image quality and enable generating three-dimensional composite images of the heart. Two-dimensional ultrasound images are obtained and stored in conjunction with correlating information, such as time or an electrocardiogram. Images related to particular conditions or configurations of the heart can be processed in combination to reduce image noise and increase resolution. Images may be processed to recognize structure edges, and the location of structure edges used to generate cartoon rendered images of the structure. Structure locations may be averaged over several images to remove noise, distortions and blurring from movement. | 06-05-2014 |
20140364719 | Method and apparatus for localizing an ultrasound catheter - An imaging system is provided with an ultrasound catheter and a controller coupled to the ultrasound catheter. The catheter includes a localizer sensor configured to generate positional information for the ultrasound catheter, and an imaging ultrasound sensor having a restricted field of view. The controller co-registers images from the imaging ultrasound sensor with positional information from the localizer sensor. | 12-11-2014 |
Patent application number | Description | Published |
20110128793 | PREAMBLE DETECTION AND POSTAMBLE CLOSURE FOR A MEMORY INTERFACE CONTROLLER - A memory controller, such as a memory controller for reading data received from a DDR SDRAM memory, may detect the beginning and end of a read cycle. The memory controller may include a preamble detection circuit to receive a strobe signal and output a first control signal indicating detection of a preamble window in the strobe signal that indicates a beginning of the read cycle, where the first control signal is delayed based on a selectable delay period applied to the first control signal. The memory controller may further include a first gate to, based on the first control signal, either output the strobe signal for reading of the data lines or block the strobe signal, and the control logic to set an amount of the selectable delay period for the preamble detection circuit. | 06-02-2011 |
20110235446 | WRITE STROBE GENERATION FOR A MEMORY INTERFACE CONTROLLER - A memory controller includes a circuit to generate a strobe signal for write operations to a DDR SDRAM. The circuit efficiently generates a glitch free strobe signal for a group of data lines. In one implementation, the memory controller includes a write data generation circuits to each transmit a data signal to the memory on a data line, the write data generation circuits being controlled by write enable signals. A write strobe generation circuit generates the strobe signal and the write enable signals, the strobe signal including a preamble window to signal the beginning of the data burst, a data transfer window, and a postamble window to signal the end of the data burst, the write strobe generation circuit generating the write enable signals a half memory cycle early and terminating the write enable signals a half memory cycle late with respect to the data signals generated by the write data generation circuits. | 09-29-2011 |
20130111156 | FLEXIBLE PIN ALLOCATION | 05-02-2013 |
Patent application number | Description | Published |
20120158670 | FINGERPRINTS DATASTORE AND STALE FINGERPRINT REMOVAL IN DE-DUPLICATION ENVIRONMENTS - A storage server is coupled to a storage device that stores blocks of data, and generates a fingerprint for each data block stored on the storage device. The storage server creates a fingerprints datastore that is divided into a primary datastore and a secondary datastore. The primary datastore comprises a single entry for each unique fingerprint and the secondary datastore comprises an entry having an identical fingerprint as an entry in the primary datastore. The storage server merges entries in a changelog with the entries in the primary datastore to identify duplicate data blocks in the storage device and frees the identified duplicate data blocks in the storage device. The storage server stores the entries that correspond to the freed data blocks to a third datastore and overwrites the primary datastore with the entries from the merged data that correspond to the unique fingerprints to create an updated primary datastore. | 06-21-2012 |
20140188952 | READING DATA WITHOUT AN INDIRECTION LOGICAL REFERENCE IDENTIFIER IN A SYSTEM THAT USES INDIRECTION ACCESS - A server that caches data in a storage system includes a data access manager that accesses data with a physical location identifier instead of a logical block reference identifier used by a filesystem that manages the cached data. The data access manager provisions a buffer from a pool of buffers maintained by the filesystem, and associates the provisioned buffer with a cache location separate from a buffer cache maintained by the filesystem. The data access manager issues a read for the data with the physical location identifier to obtain the data, and stores the data in the cache location separate from the buffer cache in the provisioned buffer. The data access manager performs a validity check on the obtained data and discards the obtained data when the validity check fails. The data access manager provides access to the buffer to a requesting program. | 07-03-2014 |
20150026424 | SYSTEMS, METHODS, AND COMPUTER PROGRAM PRODUCTS PROVIDING CHANGE LOGGING IN A DEDUPLICATION PROCESS - A method performed in a network storage system, the method including receiving a plurality of data blocks at a secondary storage subsystem from a primary storage subsystem, generating a first log that includes a first plurality of entries, one entry for each of the data blocks, in which each entry of the first plurality of entries includes a name for a respective data block and a fingerprint of the respective data block, receiving metadata at the secondary storage subsystem from the primary storage subsystem, the metadata describing relationships between the plurality of blocks and a plurality of files, generating a second log that includes a second plurality of entries, and merging the first log with the second log to generate a change log. | 01-22-2015 |
20150039572 | SYSTEM AND METHOD FOR REMOVING OVERLAPPING RANGES FROM A FLAT SORTED DATA STRUCTURE - A system and method efficiently removes ranges of entries from a flat sorted data structure, such as a fingerprint database, of a storage system. The ranges of entries represent fingerprints that have become stale, i.e., are not representative of current states of corresponding blocks in the file system, due to various file system operations such as, e.g., deletion of a data block without overwriting its contents. A deduplication module of a file system executing on the storage system performs a fingerprint verification procedure to remove the stale fingerprints from the fingerprint database. As part of the fingerprint verification procedure, the deduplication module performs an attributes intersect range calculation (AIRC) procedure on the stale fingerprint data structure to compute a set of non-overlapping and latest consistency point (CP) ranges. During the AIRC procedure, an inode associated with a data container, e.g., a file, is selected and the FBN tuple of each deleted data block in the file is sorted in a predefined, e.g., increasing, FBN order. The AIRC procedure then identifies the most recent fingerprint associated with a deleted data block. The output from the AIRC procedure, i.e., the set of non-overlapping and latest CP ranges, is then used to remove stale fingerprints associated with that deleted block (as well as each other deleted data block) from the fingerprint database. Notably, only a single pass through the fingerprint database is required to identify the set of non-overlapping and latest CP ranges, thereby improving efficiency of the storage system. | 02-05-2015 |
Patent application number | Description | Published |
20090243659 | METHOD AND DEVICE FOR DETECTING THE ABSENCE OF A PERIODIC SIGNAL - A method and device may determine the absence of a periodic signal or the absence of an edge of the periodic signal. The periodic signal may be a transmitted clock signal in a forwarded clock architecture. The periodic signal may be delayed by a fixed phase difference to produce a delayed periodic signal. The phase difference between the periodic signal and the delayed periodic signal may be determined. If the determined phase difference is above or below the fixed phase difference by a predetermined amount or more the periodic signal may be missing an edge. If the absence of the periodic signal or the absence of the edge of the periodic signal is detected, an error signal may be asserted. The error signal may be an in-band reset signal. | 10-01-2009 |
20100327936 | METHOD AND APPARATUS FOR DETERMINING WITHIN-DIE AND ACROSS-DIE VARIATION OF ANALOG CIRCUITS - Described herein is the method and apparatus for determining frequency of an oscillator coupled with one or more analog devices, and for determining within-die or across-die variations in an analog property associated with the one or more analog devices, the determining based on the oscillator frequency. The analog property includes output signal swing, bandwidth, offset, gain, and delay line linearity and range. The one or more analog devices include input-output (I/O) buffer, analog amplifier, and delay line. The method further comprises updating a simulation model file based on the determining of the within-die and/or across-die variations of the analog property. | 12-30-2010 |
20110148486 | CONTROLLED CLOCK GENERATION - Methods and systems to generate multiple phases of a clock may include a delay locked loop (DLL) to generate a bias signal to control a delay time through DLL delay elements in response to a first clock, and a plurality of a quadrature slave delay lines (SDLs), each to generate a plurality of successively phase shifted clocks over a quadrant of a corresponding selected phase of a second clock. The SDLs may be biased with the DLL bias signal to control phase differences between the generated clocks. One or more phase interpolators, such as contention based phase interpolators, may be coupled to outputs of each SDL. A frequency of the second clock may be equal to or greater than a frequency of the first clock. The SDLs may be implemented with fewer delay elements than the DLL. | 06-23-2011 |
20110148498 | DIGITAL QUADRATURE PHASE CORRECTION - Methods and systems to adjust a phase difference between signals, such as to perform quadrature phase correction. First and second signals are digitally compared, such as with exclusive OR circuitry, to provide a comparison signal having a duty cycle representative of a phase difference between the signals. A phase delay of one or both of the first and second signals is adjusted until the duty cycle of the comparison signal corresponds to a desired phase difference. In a clock and data recovery system, the signals may correspond to a zero degree phase of a first phase interpolator and a ninety degree phase of a second phase interpolator, and digital codes to the first and second phase interpolators may be adjusted to provide a fifty percent duty cycle in the comparison signal. | 06-23-2011 |
20110285469 | METHOD AND APPARATUS FOR DETERMINING WITHIN-DIE AND ACROSS-DIE VARIATION OF ANALOG CIRCUITS - Described herein is the method and apparatus for determining frequency of an oscillator coupled with one or more analog devices, and for determining within-die or across-die variations in an analog property associated with the one or more analog devices, the determining based on the oscillator frequency. The analog property includes output signal swing, bandwidth, offset, gain, and delay line linearity and range. The one or more analog devices include input-output (I/O) buffer, analog amplifier, and delay line. The method further comprises updating a simulation model file based on the determining of the within-die and/or across-die variations of the analog property. | 11-24-2011 |
20110298501 | Methods and Apparatuses for Delay-Locked Loops and Phase-Locked Loops - A low power delay-locked loop (DLL) is presented. In one embodiment, the DLL includes a phase detector which includes a reference input and a feedback input to determine a phase difference. The DLL also includes a controller to determine whether to provide a signal to both the reference input and the feedback input such that the reference input and the feedback input receive an identical input, for example, during low power operation. | 12-08-2011 |
20120019285 | METHOD AND APPARATUS FOR FAST WAKE-UP OF ANALOG BIASES - Described herein is a method and apparatus to wake-up analog bias signals with minimum delay. The apparatus comprises a first logic unit operable to adjust a signal level of a gated bias signal via a first predetermined signal in response to a power-down event; a comparator operable to compare the gated bias signal with an un-gated bias signal, and operable to generate an output signal indicating the comparison result; and a self-timed logic unit coupled to the comparator and operable to generate a wake-up signal in response to an end of the power-down event and the output signal. | 01-26-2012 |
Patent application number | Description | Published |
20130135578 | ELECTRICAL INTERCONNECTS IN AN ELECTRONIC CONTACT LENS - Ophthalmic lenses, including contact lenses may be enhanced through the incorporation of both active and passive electrical components. Electrical interconnects and die attachment configurations are required to ensure electrical connectivity between the components and the optic portion of the lens as well as providing a means for mounting planar devices on spherical surfaces. Electrical interconnects and die attachment for powered ophthalmic devices, including contact lenses includes realizing conductive traces on optical plastic, attaching planar dies to spherical surfaces and underfilling, overmolding and light blocking to complete the lens. | 05-30-2013 |
20130152386 | METHODS AND APPARATUS TO FORM ELECTRICAL INTERCONNECTS ON OPHTHALMIC DEVICES - Methods and apparatus for forming interconnects on the surfaces of three dimensional substrates, including ophthalmic devices incorporating one or more electrical components may be utilized to provide high quality electrical and mechanical connections. | 06-20-2013 |
20130174978 | METHODS AND APPARATUS TO FORM ELECTRICAL INTERCONNECTS ON OPHTHALMIC DEVICES - Methods and apparatus for forming interconnects on the surfaces of three dimensional substrates, including ophthalmic devices incorporating one or more electrical components may be utilized to provide high quality electrical and mechanical connections. | 07-11-2013 |
20130284691 | HIGH-DENSITY MASK FOR THREE-DIMENSIONAL SUBSTRATES AND METHODS FOR MAKING THE SAME - A method for fabricating high-density masks for non-planar or three-dimensional substrates utilizes a mandrel having one or more precision forms machined therein. Once the mandrel with one or more forms is fabricated, one or more mask blanks may be constructed thereon. The final masks may be cut from one or more mask blanks. | 10-31-2013 |
20150077658 | VARIABLE OPTIC OPHTHALMIC DEVICE INCLUDING SHAPED LIQUID CRYSTAL ELEMENTS AND POLARIZING ELEMENTS - This invention discloses methods and apparatus for providing an ophthalmic lens of variable optical power. The variable optic insert may have surfaces within that have differing radii of curvature. The variable optic insert may also comprise polarizing elements. In some embodiments, the variable optic insert may affect polarization components of light differently and enable a bifocal type ophthalmic device. An energy source is capable of powering the variable optic insert included within the ophthalmic lens. In some embodiments, an ophthalmic lens is cast-molded from a silicone hydrogel. The various ophthalmic lens entities may include electroactive liquid crystal layers to electrically control refractive characteristics. | 03-19-2015 |
20150077659 | VARIABLE OPTIC OPHTHALMIC DEVICE INCLUDING SHAPED LIQUID CRYSTAL ELEMENTS WITH NANO-SCALED DROPLETS OF LIQUID CRYSTAL - This invention discloses methods and apparatus for providing a variable optic insert into an ophthalmic lens. The variable optic insert may have surfaces within that have differing radii of curvature. A liquid crystal layer may be used to provide a variable optic function and in some embodiments, the liquid crystal layer may comprise droplets that are nano-scaled. An energy source is capable of powering the variable optic insert included within the ophthalmic lens. In some embodiments, an ophthalmic lens is cast-molded from a silicone hydrogel. The various ophthalmic lens entities may include electroactive liquid crystal layers to electrically control refractive characteristics. | 03-19-2015 |
20150077660 | METHOD AND APPARATUS FOR OPHTHALMIC DEVICES COMPRISING DIELECTRICS AND NANO-SCALED DROPLETS OF LIQUID CRYSTAL - This invention discloses methods and apparatus for providing a variable optic insert into an ophthalmic lens. The variable optic insert may have surfaces within that have differing radii of curvature. A liquid crystal layer may be used to provide a variable optic function and in some embodiments, the liquid crystal layer may comprise droplets that are nano-scaled. An energy source is capable of powering the variable optic insert included within the ophthalmic lens. In some embodiments, an ophthalmic lens is cast-molded from a silicone hydrogel. The various ophthalmic lens entities may include electroactive liquid crystal layers to electrically control refractive characteristics. | 03-19-2015 |
20150077661 | METHOD AND APPARATUS FOR OPHTHALMIC DEVICES INCLUDING SHAPED LIQUID CRYSTAL POLYMER NETWORKED REGIONS OF LIQUID CRYSTAL - The present invention relates to methods and apparatus for providing a variable optic insert into an ophthalmic lens. The variable optic insert may have surfaces within that have differing radii of curvature. A liquid crystal layer may be used to provide a variable optic function and in some embodiments, the liquid crystal layer may comprise polymer networked regions of interstitially located liquid crystal material. An energy source is capable of powering the variable optic insert included within the ophthalmic lens. In some embodiments, an ophthalmic lens is cast-molded from a silicone hydrogel. The various ophthalmic lens entities may include electroactive liquid crystal layers to electrically control refractive characteristics. | 03-19-2015 |
20150077662 | METHOD AND APPARATUS FOR OPHTHALMIC DEVICES COMPRISING DIELECTRICS AND LIQUID CRYSTAL POLYMER NETWORKS - The present invention relates to methods and apparatus for providing a variable optic insert into an ophthalmic lens. The variable optic insert may have surfaces within that have differing radii of curvature. A liquid crystal layer may be used to provide a variable optic function and in some embodiments, the liquid crystal layer may comprise polymer networked regions of interstitially located liquid crystal material. An energy source is capable of powering the variable optic insert included within the ophthalmic lens. In some embodiments, an ophthalmic lens is cast-molded from a silicone hydrogel. The various ophthalmic lens entities may include electroactive liquid crystal layers to electrically control refractive characteristics. | 03-19-2015 |
20150077663 | METHOD AND APPARATUS FOR OPHTHALMIC DEVICES INCLUDING HYBRID ALIGNMENT LAYERS AND SHAPED LIQUID CRYSTAL LAYERS - The present invention discloses methods and apparatus for providing a variable optic insert into an ophthalmic lens. The variable optic insert may have surfaces within that have differing radii of curvature. A liquid crystal layer may be used to provide a variable optic function and in some embodiments, an alignment layer for the liquid crystal layer may be patterned in a hybrid manner. The patterning may allow for the lowering of the minimum electrical potential required to cause a shift in orientation of liquid crystal molecules within the ophthalmic device. An energy source is capable of powering the variable optic insert included within the ophthalmic lens. In some embodiments, an ophthalmic lens is cast-molded from a silicone hydrogel. The various ophthalmic lens entities may include electroactive liquid crystal layers to electrically control optical characteristics. | 03-19-2015 |
20150077699 | METHOD AND APPARATUS FOR OPHTHALMIC DEVICES INCLUDING GRADIENT-INDEXED LIQUID CRYSTAL LAYERS AND SHAPED DIELECTRIC LAYERS - This invention discloses methods and apparatus for providing a variable optic insert into an ophthalmic lens. A liquid crystal layer may be used to provide a variable optic function and in some embodiments, an alignment layer for the liquid crystal layer may be patterned in a radially dependent manner. The patterning may allow for the index of refraction of the optic device to vary in a gradient indexed or GRIN manner. At least a first layer of dielectric material that may vary in thickness at least across the optic zone of the device may aid in defining an electric field across the liquid crystal layer. An energy source is capable of powering the variable optic insert included within the ophthalmic lens. In some embodiments, an ophthalmic lens is cast-molded from a silicone hydrogel. The various ophthalmic lens entities may include electroactive liquid crystal layers to electrically control optical characteristics. | 03-19-2015 |
20150077700 | METHODS AND APPARATUS FOR OPHTHALMIC DEVICES INCLUDING CYCLOIDALLY ORIENTED LIQUID CRYSTAL LAYERS - This invention discloses methods and apparatus for providing a variable optic insert into an ophthalmic lens. A liquid crystal layer may be used to provide a variable optic function and in some examples, an alignment layer for the liquid crystal layer may be patterned in a cycloidally dependent manner. The patterning may allow for a polarization dependent lens in some examples. An energy source is capable of powering the variable optic insert included within the ophthalmic lens. In some examples, an ophthalmic lens is cast-molded from a silicone hydrogel. The various ophthalmic lens entities may include electroactive liquid crystal layers to electrically control optical characteristics. | 03-19-2015 |
20150081016 | METHODS AND APPARATUS FOR OPHTHALMIC DEVICES INCLUDING CYCLOIDALLY ORIENTED LIQUID CRYSTAL LAYERS - This invention discloses methods and apparatus for providing a variable optic insert into an ophthalmic lens. A liquid crystal layer may be used to provide a variable optic function and in some examples, an alignment layer for the liquid crystal layer may be patterned in a cycloidally dependent manner. The patterning may allow for a polarization dependent lens in some examples. An energy source is capable of powering the variable optic insert included within the ophthalmic lens. In some examples, an ophthalmic lens is cast-molded from a silicone hydrogel. The various ophthalmic lens entities may include electroactive liquid crystal layers to electrically control optical characteristics. | 03-19-2015 |
Patent application number | Description | Published |
20120177715 | HEPARIN COFACTOR II FRAGMENTS WITH ANTI-INFLAMMATORY AND ANTI-COAGULANT ACTIVITY - The present invention provides polypeptides comprising or consisting of an amino acid sequence derived from a naturally occurring protein which modulates blood coagulation, or a fragment, variant, fusion or derivative thereof, or a fusion of said fragment, variant or derivative thereof, for use in the treatment or prevention of inflammation and/or excessive coagulation of the blood. Related aspects of the invention provide isolated polypeptides comprising or consisting of an amino acid sequence of SEQ ID NOS: 1 to 3, or a fragment, variant, fusion or derivative thereof, or a fusion of said fragment, variant or derivative thereof, which exhibit an anti-inflammatory activity, together with isolated nucleic acid molecules, vectors and host cells for making the same. Additionally provided are pharmaceutical compositions comprising a polypeptide of the invention, as well as methods of use of the same in the treatment and/or prevention of inflammation and/or excessive coagulation. | 07-12-2012 |
20120189673 | POLYPEPTIDES AND USES THEREOF - The present invention provides polypeptides comprising or consisting of an amino acid sequence derived from a naturally occurring protein which modulates blood coagulation, or a fragment, variant, fusion or derivative thereof, or a fusion of said fragment, variant or derivative thereof, for use in the treatment or prevention of inflammation and/or excessive coagulation of the blood. Related aspects of the invention provide isolated polypeptides comprising or consisting of an amino acid sequence of SEQ ID NOs: 1 to 11, or a fragment, variant, fusion or derivative thereof, or a fusion of said fragment, variant or derivative thereof which exhibit an anti-inflammatory and/or anti-coagulant activity, together with isolated nucleic acid molecules, vectors and host cells for making the same. Additionally provided are pharmaceutical compositions comprising a polypeptide of the invention, as well as methods of use of the same in the treatment and/or prevention of inflammation and/or excessive coagulation. | 07-26-2012 |
Patent application number | Description | Published |
20120193046 | BIOMASS PRETREATMENT - A method for lignocellulose conversion to sugar with improvements in yield and rate of sugar production has been developed by using ionic liquid pretreatment. This new pretreatment strategy substantially improves the efficiency (in terms of yield and reaction rates) of saccharification of lignocellulosic biomass. Cellulose and hemicellulose, when hydrolyzed into their sugars, can be converted into ethanol fuel through well established fermentation technologies. These sugars also form the feedstocks for production of variety of chemicals and polymers. The complex structure of biomass requires proper pretreatment to enable efficient saccharification of cellulose and hemicellulose components to their constituent sugars. Current pretreatment approaches suffer from slow reaction rates of cellulose hydrolysis (by using the enzyme cellulase) and low yields. | 08-02-2012 |
20130292331 | IONIC LIQUID RECOVERY AND PURIFICATION IN BIOMASS TREATMENT PROCESSES - The invention includes a process for recovering ionic liquids used in the treatment of biomass for production of biofuels and other biomass-based products. Ionic liquid recovery and purification minimizes waste production and enhances process profitability. | 11-07-2013 |
20140004563 | METHOD AND APPARATUS FOR TREATMENT OF BIOMASS SUBSTRATES | 01-02-2014 |
20140026567 | THERMAL ENERGY CONVERSION TO ELECTRICITY - A system or methodology for converting thermal energy obtained from solar thermal, photovoltaic, geothermal or industrial waste heat into electrical power is disclosed. The energy efficient way of transferring two steams of liquid solutions containing different concentrations of ionic species is disclosed. The combination of thermal gradient in addition to concentration gradient to improve efficiency, reduce or avoid fouling is disclosed. This invention describes a method of efficient ion migration from concentrated stream to dilute stream thereby improving DC power generation process. The utilization of solar thermal energy from solar collector or concentrating photovoltaic (CPV) generator system or solar thermal power generation (CSP) system provides the additional driving force for ions transport from concentrated stream to dilute stream, apart from the concentration grading to generating power. The thermal power is also used to bring back the diluted steam to original concentration in the reverse Electro dialysis system. The utilization of CPV process heat or solar or waste heat for bringing back the dilute stream into the concentrated stream for next operation of ions gradient power generation is also disclosed in this invention. | 01-30-2014 |
20140273104 | PRETREATMENT AND FRACTIONATION OF LIGNOCELLULOSIC BIOMASS - Method and apparatus for enhanced production of sugars and lignin via fractionation of lignocellulosic biomass through sequential ionic liquid pretreatment and mild alkaline treatment. The resulting biomass is easily fractionated and amenable to efficient and rapid hydrolysis and catalytic conversion to valuable products with high recovery of the enzymes used in the hydrolysis. | 09-18-2014 |
20140342420 | PRODUCTION OF BIO-BUTANOL AND RELATED PRODUCTS - The present invention provides a method for the production of an alkanol from biomass. The method for producing an alkanol, including n-butanol, comprises fermenting a carbohydrate to produce a diacid and converting the diacid into an alkanol by solution chemistry or solid phase chemistry. The carbohydrate may be derived or extracted from a lignocellulose, an algae, a grain, or a starch containing root. | 11-20-2014 |
Patent application number | Description | Published |
20120101760 | Method of Enabling Calibration of a Current Transformer, and Associated Apparatus - An improved current transformer apparatus includes a current transformer upon which are stored a number of calibration values which can be used when connecting the current transformer to a metering device. An improved method of enabling calibration of the current transformer involves deriving from a signal detected from the current transformer a number of calibration values for the current transformer and storing the calibration values in a storage disposed on the current transformer. A metering device retrieves from the storage the calibration values and applies the calibration values to a signal from the current transformer to generate a calibrated output. | 04-26-2012 |
20120101765 | Method of Identifying a Current Transformer Situated About a Conductor, and Associated Metering Device - An improved method of determining that a current transformer is situated about a conductor includes applying a predefined load to a particular conductor from among a plurality of conductors and making a determination from a signal detected from a particular current transformer responsive to the predefined load that the particular current transformer is situated about the particular conductor. An improved metering device having an algorithm for identifying the predefined load is also disclosed. | 04-26-2012 |
20140022082 | METHOD AND APPARATUS OF IDENTIFYING OR LOCATING CURRENT SENSORS - An energy monitoring system for a power conductor includes a base unit, a sensor cable, and a current sensor. The base unit includes a first indicator circuit and a first resistance electrically connected to a voltage source. The sensor cable includes a conductor. The current sensor is electrically connected to the base unit by the sensor cable. The current sensor includes a second resistance and a second indicator. The first resistance and the first indicator circuit are electrically connected to the second resistance and the second indicator by the conductor. | 01-23-2014 |
20140022083 | METHOD AND APPARATUS OF LOCATING CURRENT SENSORS - An energy monitoring system for a power conductor includes a base unit; a sensor cable; and a current sensor electrically connected to the base unit by the sensor cable. The base unit includes a first indicator circuit having a first indicator. The current sensor includes a second indicator. The first indicator circuit controls the first indicator and the second indicator to turn on simultaneously. | 01-23-2014 |
Patent application number | Description | Published |
20110293631 | MAST CELL MARKERS AND PREVENTION, DIAGNOSIS, AND THERAPY FOR CHRONIC PELVIC PAIN SYNDROME - The present invention provides compositions and methods for detection, diagnosis, treatment and/or prevention of chronic pelvic pain syndrome. In particular, the present invention provides biomarkers of chronic pelvic pain syndrome (e.g., mast cell markers (e.g., tryptase)), and/or inhibition of mast cell function (e g inhibition of MCP-1 and/or MIP-1α) to treat or prevent chronic pelvic pain syndrome. | 12-01-2011 |
20140079718 | MAST CELL MARKERS AND PREVENTION, DIAGNOSIS, AND THERAPY FOR CHRONIC PELVIC PAIN SYNDROME - The present invention provides compositions and methods for detection, diagnosis, treatment and/or prevention of chronic pelvic pain syndrome. In particular, the present invention provides biomarkers of chronic pelvic pain syndrome (e.g., mast cell markers (e.g., tryptase)), and/or inhibition of mast cell function (e.g. inhibition of MCP-1 and/or MIP-1α) to treat or prevent chronic pelvic pain syndrome. | 03-20-2014 |
Patent application number | Description | Published |
20080261900 | Compositions and Methods for Treating, Reducing, Ameliorating, or Preventing Infections Caused by Antibacterial Drug-Resistant Bacteria - Compositions comprise a fluoroquinolone having Formulae I-VIII for treating, reducing, ameliorating, or preventing infections caused by some bacteria that are resistant to an antibacterial drug. Methods for treating, reducing, ameliorating, or preventing such infections use such compositions. | 10-23-2008 |
20090196845 | OPTHALMIC COMPOSITIONS WITH AN AMPHOTERIC SURFACTANT AND AN ANIONIC BIOPOLYMER - Ophthalmic compositions that comprise 0.1 ppm to 50 ppm of a cationic antimicrobial component selected from the group consisting of biguanides, polymeric biguanides, quaternium ammonium compounds and any one mixture thereof; 0.005 wt. % to 2 wt. % of an anionic biopolymer; and 0.01 wt. % to 2 wt. % of an amphoteric surfactant of general formula I | 08-06-2009 |
20100105662 | Besifloxacin Ophthalmic Composition for the Treatment or Control of Infection - A composition comprises besifloxacin in an amount effective for treating or controlling an infection caused by an antibiotic-resistant bacterium. Such a composition can be administered to a subject for the treatment or control of bacterial conjunctivitis caused bay an antibiotic-resistant bacterium. | 04-29-2010 |
20120196840 | Compositions and Methods for Treating, Reducing, Ameliorating, or Preventing Infections - Compositions for treating, reducing, ameliorating, or preventing infections comprise a fluoroquinolone having Formulae I-VIII and an additional anti-infective agent. Methods for treating, reducing, ameliorating, or preventing such infection use such compositions. Such compositions and methods can be effective against mixed types of pathogens including certain antibiotic-resistant microbial pathogens found in such infections. | 08-02-2012 |
Patent application number | Description | Published |
20120036282 | SMART CARD DRIVEN DEVICE CONFIGURATION CHANGES - A smart card determines if the smart card has been inserted into a device, and retrieves a device identifier and at least one application configuration value from the device if the smart card has been inserted into the device. The smart card compares the retrieved device identifier and the at least one application configuration value with a device identifier and at least one application configuration value previously stored in the smart card. The smart card causes the retrieved device identifier and the at least one application configuration value to be sent to an Over The Air (OTA) server if the comparison indicates that the retrieved device identifier or the at least one application configuration value is different than the previously stored device identifier or the at least one application configuration value, so that the OTA server can supply application parameter changes to the mobile device for future device operation. | 02-09-2012 |
20120106443 | UNIVERSAL INTEGRATED CIRCUIT CARD ACTIVATION IN A HYBRID NETWORK - A universal integrated circuit card (UICC) may include a universal subscriber identity module (USIM); a code division multiple access (CDMA) subscriber identity module (CSIM); a memory to store instructions; and a processor. The processor may execute instructions to determine a type of wireless access network available to a user equipment (UE) associated with the UICC; perform activation of the UICC using the USIM, in response to detecting a CDMA enhanced High Rate Packet Data (eHRPD) network, a Global System for Mobile Communication (GSM) access network, or a Long Term Evolution (LTE) access network; and perform activation of the UICC using the CSIM, in response to detecting an available CDMA access network other than a CDMA eHRPD access network. | 05-03-2012 |
20120106533 | UNIVERSAL INTEGRATED CIRCUIT CARD UPDATES IN A HYBRID NETWORK - A universal integrated circuit card (UICC) may include a universal subscriber identity module (USIM); a code division multiple access (CDMA) subscriber identity module (CSIM); a memory to store instructions; and a processor. The processor may execute instructions to determine a type of wireless access network available to a user equipment (UE) associated with the UICC; perform updates of the UICC using the USIM, in response to detecting a CDMA enhanced High Rate Packet Data (eHRPD) network, a Global System for Mobile Communication (GSM) access network, or a Long Term Evolution (LTE) access network; and perform updates of the UICC using the CSIM, in response to detecting an available CDMA access network other than a CDMA eHRPD access network. | 05-03-2012 |
20120233357 | SMART CARD DRIVEN DEVICE CONFIGURATION CHANGES - A smart card determines if the smart card has been inserted into a device, and retrieves a device identifier and at least one application configuration value from the device if the smart card has been inserted into the device. The smart card compares the retrieved device identifier and the at least one application configuration value with a device identifier and at least one application configuration value previously stored in the smart card. The smart card causes the retrieved device identifier and the at least one application configuration value to be sent to an Over The Air (OTA) server if the comparison indicates that the retrieved device identifier or the at least one application configuration value is different than the previously stored device identifier or the at least one application configuration value, so that the OTA server can supply application parameter changes to the mobile device for future device operation. | 09-13-2012 |
20130252584 | AUTOMATIC OSCILLATING BIP SESSION FOR SIM SELF-REACTIVATION - A method and article of manufacture to reactivate a user identity card for a mobile station that communicates with a network is described. The user identity card is initially activated with the network. The user identity card has a unique identifier. Activation includes communicating with the mobile station from the network and programming the user identity card with network parameters. The network parameters programmed on the user identity card are then cleared after a preset period of time. The user identity card is reset to an unactivated state and then the user identity card can be reactivated with the network. | 09-26-2013 |
20140025537 | VERIFYING ACCESSORY COMPATIBILITY WITH A MOBILE DEVICE - Systems and techniques for providing an automated interface that enables a user of a mobile station to quickly determine whether a hardware accessory or mobile station accessory of interest is compatible with the mobile station are provided. A determination is made whether or not the mobile station accessory product is compatible with the mobile station based on the type of the mobile station and information identifying the mobile station accessory product. A message or notification indicating whether or not the mobile station accessory product is compatible with the first mobile station is automatically displayed to the user of the mobile station via an interface provided at the mobile station. | 01-23-2014 |
20140181959 | SECURE ELEMENT BIOMETRIC AUTHENTICATION SYSTEM - An input device may be in communication with an application processor, wherein the input device may be configured to receive an input and the application processor may be configured to translate the input to a received template. A secure element may be in communication with the application processor and configured to receive the received template from the application processor. The secure element may include a matcher and an enrolled template database. The matcher may be configured to compare the received template from the application processor with an enrolled template within the enrolled template database and return a match status based on the comparison. | 06-26-2014 |
20140183962 | DUAL MODE WIRELESS CHARGING SOURCE AND SINK - A first device may have a processor and a power management system configured to receive a request from a second device. The first device may receive attribute data from the second device and compare the attribute data of the second device to attribute data of the first device. The first device may then determine whether the second device is a qualifying device based on the comparison and it may also determine a power transfer mode of the first device based on whether the device is a qualifying device and on the attribute data of the first and second device. | 07-03-2014 |
20140279024 | SYSTEM FOR AND METHOD FOR A CONSUMER EXPERIENCE PLATFORM - Exemplary embodiments provide a campaign tool that enables content providers to bid for the opportunity to transmit their content mobile devices associated with consumers though a cloud based computing environment. The campaign tool is hosted by another entity. The content may be any of a variety of different contents types and may be tailored to be relevant to the consumer. The campaign tool may have a bidding system that implements one or more algorithms to manage the bidding process. The content is pushed to the mobile device following an affirmative action, such as an NFC tap, by the consumer. | 09-18-2014 |
Patent application number | Description | Published |
20080253286 | Available bandwidth estimation - Feature vectors for nodes in a network are computed based on a network metric. Clusters of the nodes are formed based on the feature vectors. A cluster head is selected for each cluster. Available bandwidths between the cluster head and nodes outside the cluster are determined. The available bandwidths between the cluster head and the nodes outside the cluster may be used as estimations of available bandwidths for the nodes in the cluster. | 10-16-2008 |
20110188372 | MINIMIZING PATHOLOGICAL FLOODING OF A NETWORK - In a method for minimizing pathological flooding of a network using a destination node, a packet is received from a source node at the destination node. The packet is transmitted from the source node to the destination node along a path. A determination is made by a node whether the packet indicates a possibility of pathological flooding. In response to a determination that the packet indicates a possibility of pathological flooding, a dummy packet is forwarded along the path to the source node. | 08-04-2011 |
20110261831 | Dynamic Priority Queue Level Assignment for a Network Flow - Forwarding a flow in a network includes receiving the flow at a switch, determining an optimized priority queue level of the flow at the switch, and forwarding the flow via the switch using an optimized priority queue level of the flow at the switch. The flow passes through a plurality of switches, including the switch, in the network, and the optimized priority queue level of the flow at the switch is different from a priority queue level of the flow at a second switch of the plurality of switches. The second switch routes the flow at the second switch using the different priority queue level for the flow. | 10-27-2011 |
20110273988 | Distributing decision making in a centralized flow routing system - Local rules for managing flows devolved from a central controller are received at a switch. The central controller determines a global set of rules for managing flows. The switch receives a packet from a flow from a network and determines whether a metric for the flow satisfies a dynamic condition to trigger a metric report to the central controller. In response to a determination that the metric for the flow at the switch satisfies the dynamic condition to trigger a metric report to the central controller, the switch sends a metric report to the central controller, and the switch then receives an instruction to manage the flow from the central controller. In response to a determination that the metric for the flow at the switch does not satisfy the dynamic condition to trigger the metric report to the central controller, the switch manages the flow using the local rules for managing flows. | 11-10-2011 |
20120131222 | ELEPHANT FLOW DETECTION IN A COMPUTING DEVICE - Example embodiments relate to elephant flow detection in a computing device. In example embodiments, a computing device may monitor a socket for a given flow. The computing device may then determine whether the flow is an elephant flow based on the monitoring of the socket. If so, the computing device may signal the network that transmits the flow that the flow is an elephant flow. | 05-24-2012 |