Patent application number | Description | Published |
20090136935 | Dye Compounds - The present disclosure provides compounds that may be used as chromogens, fluorochromes, or as both. Said compounds may further be used as substrate for at least one enzyme, wherein said enzyme is capable of processing an aromatic amine group (—NH | 05-28-2009 |
20110229975 | Hybridization Compositions and Methods - The invention provides methods and compositions for hybridizing at least one molecule to a target. The invention may, for example, eliminate the use of or reduce the dependence on formamide in hybridization. Compositions for use in the invention include an aqueous composition comprising at least one nucleic acid sequence and at least one polar aprotic solvent in an amount effective to denature double-stranded nucleotide sequences. | 09-22-2011 |
20110230664 | NEW DYE COMPOUNDS - The present disclosure provides compounds that may be used as chromogens, fluorochromes, or as both. Said compounds may further be used as substrate for at least one enzyme, wherein said enzyme is capable of processing an aromatic amine group (—NH | 09-22-2011 |
20110281263 | Compositions and Methods for Detection of Chromosomal Aberrations with Novel Hybridization Buffers - The present invention provides compositions and methods for the detection of nucleic acid sequences associated with chromosomal aberrations. The invention may, for example, eliminate the use of or reduce the dependence on formamide in hybridization. Compositions for use in the invention include an aqueous composition comprising at least one nucleic acid sequence and at least one polar aprotic solvent in an amount effective to denature double-stranded nucleotide sequences. | 11-17-2011 |
Patent application number | Description | Published |
20100105030 | NUCLEIC ACID BASE PAIRS - The invention relates to non-natural bases and base pairs that expand the normal DNA-based encoding system. Compositions herein may comprise at least one non-natural base that may interact with another base via a Watson Crick-type hydrogen bonding geometry and/or a Hoogsteen-type hydrogen bonding geometry. The bases may be used in a molecular entity, such as an oligomer or any other entity wherein the bases are attached to a backbone. For example, they may be comprised in DNA, RNA, or PNA, or a variety of other nucleic acid-type systems. | 04-29-2010 |
20100221705 | IN SITU HYBRIDIZATION DETECTION METHOD - The invention provides compositions and methods for the detection of targets in a sample; in particular, an in situ hybridization (ISH) sample. Probes and detectable labels may be provided in multiple layers in order to increase the flexibility of a detection system, and to allow for amplification to enhance the signal from a target. The layers may be created by incorporating probes and detectable labels into larger molecular units that interact through nucleic acids base-pairing, including peptide-nucleic acid (PNA) base-pairing. Optional non-natural bases allow for degenerate base pairing schemes. The compositions and methods are also compatible with immunohistochemistry (IHC), immunocytochemistry (ICC), flow cytometry, enzyme immuno-assays (EIA), enzyme linked immuno-assays (ELISA), blotting methods (e.g. Western, Southern, and Northern), labeling inside electrophoresis systems or on surfaces or arrays, and precipitation, among other general detection assay formats. The invention is also compatible with many different types of targets, probes, and detectable labels. | 09-02-2010 |
20100285467 | RAPID AND SENSITIVE METHOD FOR DETECTION OF BIOLOGICAL TARGETS - The present invention relates to a method of biological labeling that occurs via a free radical chain reaction. The labeling occurs due to deposition of a detectable reporter molecule from a media comprising a substance comprising at least two moieties of a peroxidase enzyme substrate (termed herein ‘cross-linker’) in a target site comprising peroxidase activity and a biological marker. The labeling reaction described herein may generally be used to detect targets in a host of experimental schemes for detecting and visualizing a biological or chemical target, including immunohistochemistry (IHC), in situ hybridization (ISH), antibody-based staining methods such as ELISA, Southern, Northern, and Western blotting, and others. | 11-11-2010 |
20140315204 | Immunohistochemistry Detection Method - The invention provides compositions and methods for the detection of targets in a sample; in particular, an immunohistochemistry (IHC) sample. Probes and detectable labels may be provided in multiple layers in order to increase the flexibility of a detection system, and to allow for amplification to enhance the signal from a target. The layers may be created by incorporating probes and detectable labels into larger molecular units that interact through nucleic acids base-pairing, including peptide-nucleic acid (PNA) base-pairing. Optional non-natural bases allow for degenerate base pairing schemes. The compositions and methods are compatible with immunohistochemistry (THC), but also could be used in immunocytochemistry (ICC), in situ hybridization (ISH), flow cytometry, enzyme immuno-assays (EIA), enzyme linked immuno-assays (ELISA), blotting methods (e.g. Western, Southern, and Northern), labeling inside electrophoresis systems or on surfaces or arrays, and precipitation, among other general detection assay formats. The invention is also compatible with many different types of targets, probes, and detectable labels. | 10-23-2014 |
Patent application number | Description | Published |
20090041260 | Active noise cancellation in hearing devices - Disclosed is a hearing device system comprising at least one hearing aid circuitry and at least one active noise cancellation unit, the at least one hearing aid circuitry comprises at least one input transducer adapted to convert a first audio signal to an electric audio signal; a signal processor connected to the at least one input transducer and adapted to process said electric audio signal by at least partially correcting for a hearing loss of a user; an output transducer adapted to generate from at least said processed electric audio signal a sound pressure in an ear canal of the user, whereby the generated sound pressure is at least partially corrected for the hearing loss of the user; the at least one active noise cancellation unit being adapted to provide an active noise cancellation signal adapted to perform active noise cancellation of an acoustical signal entering the ear canal in addition to said generated sound pressure, wherein the hearing device system further comprises a combiner unit adapted to combine the processed electric audio signal with the active noise cancellation signal, to obtain a combined signal and to provide the combined signal to the output transducer. | 02-12-2009 |
20100195858 | HEARING DEVICE - The invention relates to a hearing device | 08-05-2010 |
20110096948 | HEARING INSTRUMENT COMPRISING A DIVIDED WAX FILTER - The invention relates to a hearing instrument comprising an ITE-part adapted for being positioned in the ear canal of a user, the ITE-part comprising a housing comprising first and second openings adapted for facing towards the ear drum when said ITE-part is mounted in the ear canal, said first and second openings being adapted to allow first and second functional elements of the ITE-part to be in communication with the ear canal, the hearing instrument further comprising a wax filter adapted to fully or partially cover said first and second openings. The invention further relates to the use of a hearing instrument, to a method of wax protection in a hearing instrument and to a wax filter. The object of the present invention is to provide an alternative solution to protect relevant parts of a hearing aid against wax deposition. The problem is solved in that the wax filter comprises at least first and second distinctly different parts for covering respectively, said first and second openings, each of said first and second distinctly different parts of the wax filter being individually optimized. This has the advantage of providing a flexible one-piece wax filter that is optimized according to need. The invention may e.g. be used for the hearing instruments comprising an in-the-ear-part. | 04-28-2011 |
20120169454 | LISTENING SYSTEM COMPRISING AN ALERTING DEVICE AND A LISTENING DEVICE - A listening system that eases the acknowledgement of ‘alarm signals’, as e.g. issued by alarm indicators, in the environment of a user in difficult listening situations. The listening system is adapted to issue specific ALARM mode signals to the user corresponding to said external alarm signals, when said listening system is in an ALARM mode. An advantage of the present system is that a user is able to take notice of alarms from normal indicators even in case of a hearing impairment and/or when located in a noisy environment. The system may e.g. be used for the hearing instruments, ear protection devices, earphones, headsets or combinations thereof. | 07-05-2012 |
20140072157 | MAGNETIC CONNECTOR - Acoustic duct connector for an acoustic duct of the type being used for real ear measurements, the acoustic duct connector comprising a first surface portion and a first acoustic duct exiting from said first surface portion, and comprising a first magnetical component for engaging to a second magnetical component comprised by a receiving connector such, that an airborne sound signal can propagate from the first acoustic duct to a second acoustic duct exiting from a second surface portion of the receiving connector when the acoustic duct connector and the receiving connector are connected to each other. | 03-13-2014 |
20140321682 | HEARING ASSISTANCE DEVICE WITH A LOW-POWER MODE - A portable hearing assistance device comprises an input unit, an output unit, a forward path between the input unit and the output unit, and an energy source for energizing components of the hearing assistance device. The hearing assistance device further comprises a control unit to control activation (or deactivation) of a low-power mode of operation of the hearing assistance device. When the low-power mode is activated—the draw of current from said energy source is reduced compared to a normal mode of operation of the device, the activation (or deactivation) being influenced by a combination of at least two different control input signals to the control unit, each control input signal being a signal selected from 1) signals relating to current physical environment, 2) signals relating to current acoustic environment, 3) signals relating to current wearer state, and 4) signals relating to current state or operation mode. | 10-30-2014 |
20140376756 | EAR STRAP FOR A PROBE TUBE - An ear strap is disclosed. The ear strap comprises attachment means configured to be attached to a tube. The ear strap has a flexible member configured to be placed within the concha of the ear and to be held in place by the concha of the ear. The flexible member is configured to take a form that fits the shape of the concha of the ear. The ear strap comprises means for adjusting the position of the tube relative to the attachment means. | 12-25-2014 |
20150049892 | EXTERNAL MICROPHONE ARRAY AND HEARING AID USING IT - An external microphone array is configured to be used with a hearing aid and comprises a number of microphones configured to detect one or more sound signals from a sound source and means for wirelessly sending the detected sound signal to at least one hearing aid. The external microphone array comprises means for automatically determining the direction of the sound source either by: a) receiving a wireless signal transmitted from a remote control; b) by receiving acoustic signals picked up by the hearing aid(s) and by further comparing the signals with signals received by the external microphone array. The external microphone array may e.g. take the form of a sphere, a hemi-sphere or a neckband. | 02-19-2015 |
20150078601 | FILTER MEMBER - A replaceable filter member for a hearing aid device is disclosed. The filter member comprising an unit with a housing configured to be inserted into the ear canal of a user of the hearing aid device. The filter member is configured to prevent ear wax from entering an opening in the housing. The filter member is a one-piece body that is configured to cover several openings in the unit while being attached to the unit. | 03-19-2015 |
20150230036 | HEARING AID DEVICE COMPRISING A SENSOR MEMBER - A hearing aid device is disclosed. The hearing aid device comprises means to improve, augment and/or protect the hearing capability of a user by receiving acoustic signals from the surroundings of the user, generating corresponding audio signals, possibly modifying the audio signals and providing the possibly modified audio signals as audible signals to at least one of the user's ears. The hearing aid device comprises a sensor member for detecting the movement and/or acceleration and/or orientation (or spatial position) of the hearing aid device. The hearing aid device comprises at least two hearing aid microphones and a control unit for determining the position or a deviation from an intended position of the hearing aid device or hearing aid microphones. The hearing aid device is configured to compensate for a possible dislocation of the hearing aid microphones. | 08-13-2015 |