Ottens
Andrew K. Ottens, Gainesville, FL US
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20080204043 | Real-Time Assessment of Biomarkers for Disease - A system and methods, thereof, monitor biomarkers from a patient suffering from neural injury in real-time. The system comprises a quartz crystal microbalance wherein a capture molecule specific for certain biomarkers is diagnostic of the type of neural injury, location of neural injury and the degree of severity of neural injury. The system, in particular, provides real-time continuous monitoring of a patient. | 08-28-2008 |
Andrew K. Ottens, Glen Allen, VA US
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20100047817 | Synaptotagmin and Collapsin Response Mediator Protein as Biomarkers for Traumatic Brain Injury - Collapsin response mediator proteins (CRMPs) decreased in tissue and increased in biological fluids after neural injury from traumatic brain injury (TBI). Significant decreases of CRMP1, CRMP2, CRMP4 and CRMP5 were accompanied by the appearance of distinct 58 kDa (CRMP-2) or 55 kDa (CRMP-4) breakdown products from proteolytic cleavage by calpain. Synaptotagmin breakdown products were also associated with TBI and could be detected along with intact protein in human cerebral spinal fluid (CSF). Both biomarkers were detected in human biofluid and related to recovery from traumatic brain injury. | 02-25-2010 |
20120196307 | SYNAPTOTAGMIN AND COLLAPSIN RESPONSE MEDIATOR PROTEIN AS BIOMARKERS FOR TRAUMATIC BRAIN INJURY - Collapsin response mediator proteins (CRMPs) decreased in tissue and increased in biological samples after neural injury from traumatic brain injury (TBI). Significant decreases of CRMP1, CRMP2, CRMP4 and CRMP5 were accompanied by the appearance of distinct 58 kDa (CRMP-2) or 55 kDa (CRMP-4) breakdown products from proteolytic cleavage by calpain. Synaptotagmin breakdown products were also associated with TBI and could be detected along with intact protein in human cerebral spinal fluid (biological samples). Both biomarkers were detected in human biofluid and related to recovery from traumatic brain injury. | 08-02-2012 |
Benjamin Ottens, Hamburg DE
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20150216608 | ADAPTER IDENTIFICATION OF A REPROCESSING DEVICE FOR SURGICAL INSTRUMENTS - An adapter device for use in a reprocessing device for reprocessing surgical instruments. The adapter device including: at least one first fluid attachment, on an inlet side for connection to a coupling device of the reprocessing device; at least one second fluid attachment, on an outlet side for connection to the surgical instrument, the at least one second fluid attachment being adapted geometrically to an attachment of the surgical instrument; and an adapter identification feature that is detectable by the reprocessing device. Also provided is a reprocessing system having a reprocessing device for reprocessing surgical instruments and having the adapter device. The reprocessing device including: the coupling device for connecting to the adapter device; and a detection device which detects, with the adapter device connected to the reprocessing device, the adapter identification feature of the adapter device. | 08-06-2015 |
Joost Jeroen Ottens, Velhoven NL
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20090303455 | LITHOGRAPHIC APPARATUS AND DEVICE MANUFACTURING METHOD - A porous member is used in a liquid removal system of an immersion lithographic projection apparatus to smooth uneven flows. A pressure differential across the porous member may be maintained at below the bubble point of the porous member so that a single-phase liquid flow is obtained. Alternatively, the porous member may be used to reduce unevenness in a two-phase flow. | 12-10-2009 |
Joost Jeroen Ottens, Tr Veldhoven NL
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20110096307 | LITHOGRAPHIC APPARATUS AND DEVICE MANUFACTURING METHOD - An immersion lithographic apparatus is disclosed in which at least a part of the liquid supply system (which provides liquid between the projection system and the substrate) is moveable in a plane substantially parallel to a top surface of the substrate during scanning. The part is moved to reduce the relative velocity between that part and the substrate so that the speed at which the substrate may be moved relative to the projection system may be increased. | 04-28-2011 |
Marcel Ottens, Leiden NL
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20080274953 | Method of Preparing a Protein Aggregate and a Pharmaceutical Preparation - The invention relates to a method of preparing a protein aggregate, wherein an aqueous protein solution is acidified with a pH that lies above the isoelectric point of the protein. In accordance with the invention, a first protein, which through acidification is able to form a protein aggregate, is acidified in the presence of a second protein in the aqueous solution in order to form a coaggregate comprising the first and second protein, wherein the second protein under identical temperature conditions and pH does not form a protein aggregate in the absence of the first protein. Acidification preferably occurs with the aid of CO | 11-06-2008 |
Timothy S. Ottens, Stanton, MO US
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20110034332 | Herbicidal compositions containing N-phosphonomethyl glycine and an auxin herbicide - Herbicidal compositions are provided which cause rapid symptomology while delivering long term control of regrowth of plants. The herbicidal concentrate compositions comprise N-phosphonomethylglycine or a herbicidal derivative thereof, an auxin herbicide or a herbicidal derivative thereof, and at least one surfactant. Also provided is a method for killing or controlling the growth of certain plants by contacting the foliage of the plants with the diluted concentrate composition. | 02-10-2011 |
20140364313 | HERBICIDAL COMPOSITIONS CONTAINING N-PHOSPHONOMETHYL GLYCINE AND AN AUXIN HERBICIDE - Herbicidal compositions are provided which cause rapid symptomology while delivering long term control of regrowth of plants. The herbicidal concentrate compositions comprise N-phosphonomethylglycine or a herbicidal derivative thereof, an auxin herbicide or a herbicidal derivative thereof, and at least one surfactant. Also provided is a method for killing or controlling the growth of certain plants by contacting the foliage of the plants with the diluted concentrate composition. | 12-11-2014 |