Patent application number | Description | Published |
20100081802 | Synthesis of Phosphitylated Compounds Using a Quaternary Heterocyclic Activator - A method for preparing a phosphitylated compound comprising the step of: -reacting hydroxyl containing compound with a phosphitylating agent in the presence of an activator having the formula (I) wherein R=alkyl, cycloalkyl, aryl, aralkyl, heteroalkyl, heteroaryl R | 04-01-2010 |
20100087635 | PURIFICATION OF OLIGONUCLEOTIDES - A method for purifying a protected oligonucleotide comprising the steps of:
| 04-08-2010 |
20110065909 | SYNTHESIS OF OLIGONUCLEOTIDES - A method for preparing an oligonucleotide comprising the steps of | 03-17-2011 |
20120316328 | SYNTHESIS OF PHOSPHITYLATED COMPOUNDS USING A QUATERNARY HETEROCYCLIC ACTIVATOR - A method for preparing a phosphitylated compound comprising the step of:—reacting a hydroxyl containing compound with a phosphitylating agent in the presence of an activator having the formula (I) wherein R=alkyl, cycloalkyl, aryl, aralkyl, heteroalkyl, heteroaryl R | 12-13-2012 |
20120322994 | SYNTHESIS OF OLIGONUCLEOTIDES - A method for preparing an oligonucleotide comprising the steps of
| 12-20-2012 |
20130066061 | PURIFICATION OF OLIGONUCLEOTIDES - A method for purifying a protected oligonucleotide comprising the steps of:
| 03-14-2013 |
20130303745 | Synthesis of oligonucleotides - A method for preparing an oligonucleotide comprising the steps of synthesizing a phosphoramidite by reacting a hydroxyl-containing compound of formula (A) with a phosphitylating agent in the presence of an activator compound of formula (I), to prepare a phosphitylated compound, then coupling the phosphitylated compound without isolation with a second compound having the formula (A), wherein R | 11-14-2013 |
Patent application number | Description | Published |
20100081802 | Synthesis of Phosphitylated Compounds Using a Quaternary Heterocyclic Activator - A method for preparing a phosphitylated compound comprising the step of: -reacting hydroxyl containing compound with a phosphitylating agent in the presence of an activator having the formula (I) wherein R=alkyl, cycloalkyl, aryl, aralkyl, heteroalkyl, heteroaryl R | 04-01-2010 |
20110065909 | SYNTHESIS OF OLIGONUCLEOTIDES - A method for preparing an oligonucleotide comprising the steps of | 03-17-2011 |
20110201799 | Synthesis of oligonucleotides - A method for preparing an oligonucleotide comprising the steps of a) providing a hydroxyl containing compound having formula (1), wherein B is a heterocyclic base, and radicals R | 08-18-2011 |
20120316328 | SYNTHESIS OF PHOSPHITYLATED COMPOUNDS USING A QUATERNARY HETEROCYCLIC ACTIVATOR - A method for preparing a phosphitylated compound comprising the step of:—reacting a hydroxyl containing compound with a phosphitylating agent in the presence of an activator having the formula (I) wherein R=alkyl, cycloalkyl, aryl, aralkyl, heteroalkyl, heteroaryl R | 12-13-2012 |
20120322994 | SYNTHESIS OF OLIGONUCLEOTIDES - A method for preparing an oligonucleotide comprising the steps of
| 12-20-2012 |
20130066061 | PURIFICATION OF OLIGONUCLEOTIDES - A method for purifying a protected oligonucleotide comprising the steps of:
| 03-14-2013 |