Nguy
Darren Nguy, Derrimut AU
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20140154233 | METHOD OF PURIFYING THERAPEUTIC PROTEINS - The present invention relates generally to a method of reducing the level of plasminogen and/or tissue plasminogen activator and/or other protease(s) in a solution comprising fibrinogen and/or Factor VIII and/or von Willebrand factor (VWF), the method comprising: (i) passing a feedstock comprising fibrinogen and/or Factor VIII and/or VWF through a hydrophobic charge-induction chromatographic resin under conditions selected such that the plasminogen and/or tissue plasminogen activator and/or other protease(s) is bound to the resin; and (ii) recovering the solution comprising fibrinogen and/or Factor VIII and/or VWF which passes through the resin; wherein the concentration of the plasminogen and/or tissue plasminogen activator and/or protease(s) in the recovered solution is reduced by at least 50% compared to the feedstock. Also provided are solutions and pharmaceutical formulations comprising the fibrinogen and/or Factor VIII and/or VWF recovered by such methods, and uses thereof. | 06-05-2014 |
20150158906 | Method of Purifying Therapeutic Proteins - The present invention relates generally to a method of reducing the level of at least one protein selected from the group consisting of plasminogen, tissue plasminogen activator and other protease(s) in a solution comprising at least one protein selected from the group consisting of fibrinogen, Factor VIII and von Willebrand factor (VWF), the method comprising: | 06-11-2015 |
Darren Nguy, Derrimut, Victoria AU
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20150366947 | A Method of Purifying Therapeutic Proteins - The present invention relates generally to a method of reducing the level of at least one protein selected from the group consisting of plasminogen, tissue plasminogen activator and other protease(s) in a solution comprising at least one protein selected from the group consisting of fibrinogen, Factor VIII and von Willebrand factor (VWF), the method comprising: (i) passing a feedstock comprising at least one protein selected from the group consisting of fibrinogen, Factor VIII and VWF through a hydrophobic charge-induction chromatographic resin under conditions selected such that at least one protein selected from the group consisting of plasminogen, tissue plasminogen activator and other protease(s) present in the feedstock is bound to the resin; and (ii) recovering a solution comprising the at least one protein selected from the group consisting of fibrinogen, Factor VIII and VWF which passes through the resin, wherein the concentration of the at least one protein selected from the group consisting of plasminogen, tissue plasminogen activator and other protease(s) in the solution is reduced by at least 50% compared to the feedstock. Also provided are solutions and pharmaceutical formulations comprising the fibrinogen and/or Factor VIII and/or VWF recovered by such methods, and uses thereof. | 12-24-2015 |
Vi Nguy, Calgary CA
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20080236840 | THERMAL ACTUATOR - An embodiment of a system for disconnecting a first element from a second element at a desired position in a wellbore includes a disconnect tool containing an expandable material, the disconnect tool being actuatable from a locked position, wherein the first and the second elements are interconnected, to an unlocked position, wherein the first and the second element are disconnected, upon a determined expansion of the expandable material in response to a temperature at the desired position. | 10-02-2008 |
20090206552 | SHAPE MEMORY (ALLOY) HERMETIC SEAL AND THREADED JOINT INCORPORATING SAME - A hermetic seal includes a face seal ring having a first end sealing face and a second end sealing face, a first sealing profile in contact with the first end sealing face, and a second sealing profile in contact with the second end sealing face. The face seal ring comprises a shape memory material. A hermetically-sealed, threaded joint includes a pin sub defining a first sealing profile, a box sub defining a second sealing profile, and a face seal ring comprising a shape memory material. The pin sub is threadedly engaged with the box sub. The face seal ring has a first end sealing face in contact with the first sealing profile and a second end sealing face in contact with the second sealing profile. The face seal ring is disposed about the pin sub. | 08-20-2009 |
20110073210 | COILED TUBING HAVING A CAPILLARY WINDOW AND METHOD FOR MAKING SAME - A coiled tubing assembly includes coiled tubing having a side wall that defines an opening and an insert covering the opening and affixed to the coiled tubing. The coiled tubing has a longitudinal axis. The insert defines a capillary window therethrough. The opening and the insert include ends that are non-perpendicular to the longitudinal axis. A method of making a coiled tubing assembly includes providing coiled tubing defining a side wall opening and pulling a capillary tube into the interior of the coiled tubing through the side wall opening. The method further includes attaching the capillary tube to a capillary window of an insert for covering the side wall opening and affixing the insert to the coiled tubing. | 03-31-2011 |
20120186814 | System And Method For Preserving A Hydraulic Packer - A technique facilitates use of a hydraulically actuated packer in a high temperature, downhole environment. The packer is actuated by directing pressurized fluid to the packer and routing the fluid to an actuation region of the packer to provide the force for setting the packer. A thermal isolation member is positioned in the packer along the pressurized fluid flow path and activates upon exposure to heat. Once the thermal isolation member is fully activated, flow is blocked along the pressurized fluid flow path which prevents return flow of pressurized fluid. | 07-26-2012 |
Vi Nguy, Shanghai CN
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20140208570 | Method for Making a Coiled Tubing Assembly - A coiled tubing assembly includes coiled tubing having a side wall that defines an opening and an insert covering the opening and affixed to the coiled tubing. The coiled tubing has a longitudinal axis. The insert defines a capillary window therethrough. The opening and the insert include ends that are non-perpendicular to the longitudinal axis. A method of making a coiled tubing assembly includes providing coiled tubing defining a side wall opening and pulling a capillary tube into the interior of the coiled tubing through the side wall opening. The method further includes attaching the capillary tube to a capillary window of an insert for covering the side wall opening and affixing the insert to the coiled tubing. | 07-31-2014 |
Vi (jim) Nguy, Calgary CA
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20110259595 | Mechanical Sliding Sleeve - A mechanical sliding sleeve ( | 10-27-2011 |
20110260451 | Barrier Seal and Assembly Incorporating Same - A barrier seal includes a bulkhead having a first end, a second end and a surface extending between the first end and the second end. The barrier seal further includes a rib extending radially outwardly from the surface of the bulkhead. The rib defines a first sealing profile extending from a first side of the rib and a second sealing profile extending from a second side of the rib. | 10-27-2011 |
Vi Van Nguy, Shanghai CN
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20160053555 | CABLE PROTECTOR SYSTEM - A technique provides a cable protector in the form of a modular unit having a protector shell and at least one removable insert. The removable insert is constructed with gaps which are sized to grippingly engage a cable. Accordingly, a properly sized removable insert is selected for use with a given cable and then inserted into the protector shell. The cable protector may then be secured to a tubing, e.g. a well tubing, by an appropriate tubing coupling. In some embodiments, the tubing coupling is coupled about the tubing via a threaded fastener which may be held in place by a back off preventer. | 02-25-2016 |