Neethling
Francisca A. Neethling, Tuscola, TX US
Patent application number | Description | Published |
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20090075304 | METHODS OF ASSAYING VACCINE POTENCY - The present invention is related to methods of assaying potency of a vaccine composition, wherein the potency is a pre-defined minimum level of potential biological activity for the vaccine composition. The method includes providing a vaccine composition and delivering same to an antigen presenting cell, wherein the vaccine composition is processed into peptides and the peptides are presented by MHC complexes on the cell surface. An agent, such as a T cell receptor mimic, that is reactive against a specific peptide/MHC complex is provided and reacted with the vaccine-treated antigen presenting cell, whereby the agent binds to the cell surface of the vaccine-treated antigen presenting cell if the specific peptide/MHC complex recognized by the agent is present on the cell surface. A density of the specific peptide/MHC complex on the surface of the vaccine-treated antigen presenting cell is measured by agent binding. The potency of the vaccine is then determined based upon the measured density of specific peptide/MHC complex present on the surface of the vaccine-treated antigen presenting cell. | 03-19-2009 |
Marthinus Phillipus Neethling, Randburg ZA
Patent application number | Description | Published |
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20150312424 | MANAGING OF CONSUMPTION TYPE SERVICE CONTRACTS - The invention relates to a method for managing contracts for consumption type services which includes smoothing requests for enactment of UE contracts, by determining a time-to-live in respect of each UE contract, determining an estimate of the number of concurrent requests for contracts to occur at predetermined future time intervals, and modifying the actual issued time-to-live in respect of at least some of the enacted UE contracts to minimize network load. The method also extends to determining a trust-rating for at least some of the UE's contracted to a service provider for the consumption type service and modifying the trust-rating for such UE over time to more accurately reflect the actual trustworthiness of contract requests emanating from such UE. | 10-29-2015 |
Rufus Stephanus Neethling, Gemiston ZA
William Morris Leonard Neethling, Booragoon AU
Patent application number | Description | Published |
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20130122583 | STERILIZATION PROCESS - The present invention relates to a process for sterilizing implantable biomaterials. In particular, the invention relates to a process for sterilizing collagen-containing implantable biomaterials and storage thereafter. | 05-16-2013 |