Munafo
Alain Munafo, Tartegnin CH
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20090186040 | DOSING METHODS FOR TREATING AUTOIMMUNE DISEASES USING A TACI-Ig FUSION PROTEIN SUCH AS ATACICEPT - In various embodiments, the present invention provides methods, compositions, dosing, and administration schedules for treatment of autoimmune diseases, including systemic erythematosus (SLE), for example, comprising administering to a patient in need of such treatment a TACI-Ig fusion molecule such as atacicept. In one embodiment, the TACI-Ig fusion molecule is administered in amount sufficient to slow, suppress or inhibit proliferation-inducing functions of BLyS and APRIL, in particular the use of multiple administrations of the fusion molecule at relatively low dose over the course of the treatment. | 07-23-2009 |
20100203017 | Cladribine Regimen for Treating Multiple Sclerosis - The present invention is related to the use of Cladribine for the preparation of a pharmaceutical formulation for the treatment of multiple sclerosis, especially relapsing-remitting multiple sclerosis or early secondary progressive multiple sclerosis, wherein the preparation is to be the orally administered and wherein re-treatments are possible. | 08-12-2010 |
Daniela Munafo, South Hamilton, MA US
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20130157869 | Method for Reducing Adapter-Dimer Formation - Methods are provided for ligating a 3′ adapter and a 5′ adapter to a target polynucleotide so as to avoid adapter dimer formation. Embodiments of the methods include adding a blocking oligonucleotide after the first ligation in which a 3′ adapter is ligated to the target polynucleotide so that the blocking oligonucleotide is capable of hybridizing to excess 3′ adapter and the ligated 3′ adapter. Subsequently, a 5′ adapter is ligated to the target polynucleotide thus avoiding adapter dimer formation. | 06-20-2013 |
20150072870 | Method for Reducing Adapter-Dimer Formation - Methods are provided for ligating a 3′ adapter and a 5′ adapter to a target polynucleotide so as to avoid adapter dimer formation. Embodiments of the methods include adding a blocking oligonucleotide after the first ligation in which a 3′ adapter is ligated to the target polynucleotide so that the blocking oligonucleotide is capable of hybridizing to excess 3′ adapter and the ligated 3′ adapter. Subsequently, a 5′ adapter is ligated to the target polynucleotide thus avoiding adapter dimer formation. | 03-12-2015 |
Dominic Munafo, San Diego, CA US
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20160048671 | SLEEP DATA CHAIN OF CUSTODY - A wearable device includes one or more biometric sensors, each of the one or more biometric sensors gathering biological data from a wearer of the wearable device, the wearable device further having a computer processor for receiving the biological data from the one or more biometric sensors and generating biometric information based on the biological data and according one or more biometrical algorithms, the biometric information including validation information to validate the wearer as a source of the biological data gathered by each of the one or more sensors, the biometric information further including sleep information to provide a sleep profile of the wearer. | 02-18-2016 |
John Munafo, Belterose, NY US
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20110119807 | Article for alleviating bunion deformity and pain - An article for overcoming the inward deforming tendency of the big toe of a person suffering from bunions is herein disclosed. The article is constructed of stretch fabric in the form of a tube sock which transitions in the region encompassing the toes, into two distinct pockets. A first elongated pocket encompasses the second through fifth toes, while the other pocket encompasses the big toe. A gap between the pockets works in combination with multiple layers of elastomeric material knit in a long but narrow band on the outside of the big toe and running down the side of the sock. When the sock is donned, the band of elastomeric material creates compressive restoring forces that draw the big toe pocket, and thus the big toe, outwardly from the other toes. Continuous use of the article serves to stretch tight tendons and toes muscles, and deter bunion pain and deformity. | 05-26-2011 |
John P. Munafo, Hackettstown, NJ US
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20090203926 | PROCESS FOR SELECTIVELY EXTRACTING PROCYANIDINS - A process is described for selectively extracting cocoa procyanidins from an aqueous mixture of cocoa polyphenols by using a particular sequence of solvents to extract selected procyanidin monomers and/or oligomers. The solvents are n-butyl acetate, ethyl acetate, methyl acetate, diethyl ether, or mixtures of methyl acetate and diethyl ether. Preferably, the aqueous mixture of cocoa polyphenols is first extracted with n-butyl acetate. The mixtures of methyl acetate and diethyl ether are between 25:75 and 75:25 (v/v). | 08-13-2009 |
20100183791 | ORGANOLEPTICALLY ENHANCED WHITE CHOCOLATE - This invention is directed to an enhanced white chocolate to which has been added isovaleric acid in an amount effective to provide enhanced organoleptic attributes compared to a conventional white chocolate. The invention is also directed to the preparation of the enhanced white chocolate. | 07-22-2010 |
20140205729 | FLAVOR COMPOSITION AND EDIBLE COMPOSITIONS CONTAINING SAME - A flavor composition containing at least one dipeptide or tripeptide compound that can be used to enhance the taste of edible compositions including sweet goods, such as confectionery goods, and savory goods, such as pet foods. | 07-24-2014 |
20150342231 | FLAVOR COMPOSITION AND EDIBLE COMPOSITIONS CONTAINING SAME - A flavor composition comprising a peptide which comprises pyroglutamic acid or γ-glutamic acid, a second amino acid and optionally a third amino acid. The peptides can be added to a food product to increase saltiness, umami, bitterness, astringency or sourness intensity. | 12-03-2015 |
20160000127 | MANGO FLAVOR COMPOSITIONS - The presently disclosed subject matter is directed to a flavor system, where by specific base flavors are created and manipulated with specific cultivar character components to establish a spectrum of flavors within a target flavor. Specifically, the presently disclosed subject matter discloses mango base flavor compositions containing (a) a furanone compound, (b) an ester compound, (c) an aldehyde compound, (d) a hydrocarbon compound, and (e) a lactone compound. The base flavor compositions can be used alone or in combination with specific cultivar character components to meet flavor preferences across different regions. | 01-07-2016 |
Salvatore Munafo, Santa Venerina (ct) IT
Patent application number | Description | Published |
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20110318432 | COMPOSITIONS FOR THE TREATMENT OF GASTRO-ESOFAGEAL REFLUX DISEASE (GERD) - Oral pharmaceutical, nutraceutical, health foods and medical device compositions based on polysaccharides from | 12-29-2011 |
20120183627 | COMPOSITIONS FOR THE TREATMENT OF HEMORRHOIDS AND RELATED DISEASES - The present invention relates to pharmaceutical, nutraceutical, health foods and medical device compositions comprising polysaccharides from | 07-19-2012 |