Patent application number | Description | Published |
20080318916 | Novel alpha glucosidase inhibitors from lichens - This invention is directed to a novel method for the inhibition of α-glucosidase enzyme and thus treating diabetes, viral infections, fungal infections, autoimmune function disorders and obesity using compounds derived as lichen metabolites; more specifically, this includes the therapeutic applications of methylorsellinate (2,4-dihydroxy-6-methylbenzoate, Compound I), methyl-β-orinolcarboxylate (2,4-dihydroxy-3,6-dimethylbenzoate, Compound II) and zeorin (6,22-hopanediol, Compound III). | 12-25-2008 |
20090048332 | Natural Novel Antioxidants - New antioxidants derived from lichen extracts are reported; lecanoric acid, erythrin, sekikaic acid, and lobaric acid were reported as potent natural antioxidants for the treatment of disease and protection of products from the effect of oxidizing components. | 02-19-2009 |
20090136434 | Tyrosinase enzyme inhibitors from fungal hydroxylation of tibolone - Seven new and one known metabolites of tibolone were obtained by incubation of tibolone with various fungi. Their structures were elucidated by means of a homo and heteronuclear 2D NMR and by HREI-MS techniques. The relative stereochemistry was deduced by 2D NOESY experiment. These metabolites of tibolone were strong inhibitors of tyrosine enzyme and thus useful in producing skin lightning and preserving fruits and vegetables. | 05-28-2009 |
20130018025 | Anticancer CompoundAANM Saifullah;AACI KarachiAACO PKAAGP Saifullah; Karachi PKAANM Khan; SaifullahAACI KarachiAACO PKAAGP Khan; Saifullah Karachi PKAANM Azizuddin;AACI KarachiAACO PKAAGP Azizuddin; Karachi PKAANM Kashif; MuhammadAACI KarachiAACO PKAAGP Kashif; Muhammad Karachi PKAANM Dar; AhsanaAACI KarachiAACO PKAAGP Dar; Ahsana Karachi PKAANM Choudhary; Muhammad IqbalAACI KarachiAACO PKAAGP Choudhary; Muhammad Iqbal Karachi PK - cell suspension culture is used to metabolize dianabol to yield potent anticarcinogenic 17β-hydroxy-17α-methyl-5α-androst-1-en-3-one, which can also be synthesized. | 01-17-2013 |
20140200189 | ARTONI I TO TREAT RESISTANT INFECTIOUS STAPHYLOCOCCUS AUREUS - Artonin I is reported to treat multi-drug resistant | 07-17-2014 |
20140221429 | HETEROCYCLIC SCHIFF'S BASES AS NOVEL AND NEW ANTIGLYCATION AGENTS - The invention provides that heterocyclic Schiff bases posses protein antiglycation potential in hyperglycemia. The novel antiglycation agents 3-6 showed a moderate to potent antiglycation activity. | 08-07-2014 |
20140256754 | QUINAZOLINES AS B-GLUCURONIDASE NOVEL INHIBITORS - Quinazoline derivatives 1-25, (2-[3,4-bis(methyloxy)phenyl]quinazolin-4-(3H)-one) and 2-[2-(ethyloxy)phenyl]quinazoline-4-(3H)-one) are reported as β-glucuronidase inhibitors useful in the treatment of β-glucuronidase hyperactivity disorders. | 09-11-2014 |
20150038543 | ANTI-GLYCATION PROPERTIES OF OXINDOLE DERIVATIVES - This invention provides a series of new oxindole derivatives 1-21, evaluated for their antiglycation potential by using in vitro BSA-MG glycation model. These derivatives showed a varying degree of antiglycation activity with IC | 02-05-2015 |
20150051286 | ANTHRANILIC ACID DERIVATIVES: NOVEL INHIBITORS OF ADVANCED GLYCATION END-PRODUCTS (AGES) FORMATION - Anthranilic acid derivatives are used to inhibit the formation of advanced glycation end products to reduce complications in diabetes. | 02-19-2015 |
20150080580 | THIOUREA DERIVATIVES AS a-CHYMOTRYPSIN INHIBITORS - α-Chymotrypsin inhibitors of thiourea class are reported that could be potent inhibitors of proteases, elastases, proteasomes, NS3 and NS4 serine protease of hepatitis C virus, dengue virus, etc. Compounds | 03-19-2015 |