Patent application number | Description | Published |
20090191216 | Antibody or a fragment thereof, having neutralizing activity against HIV - The invention relates to a monoclonal antibody or a fragment thereof, recognizing a peptide of sequence set forth as SEQ ID NO 7 or an analogue thereof, wherein the complementarity determining region 3 (CDR3) of its H chain variable region comprises the peptide sequence set forth as SEQ ID NO 1 or a functional analogue thereof. | 07-30-2009 |
20090202622 | VIROSOME-LIKE VESICLES COMPRISING GP41-DERIVED ANTIGENS - The present invention relates to a virosome-like vesicle comprising at least a gp41-derived antigen or an analogue thereof, said gp41-derived antigen being located to the external surface of and/or encapsulated inside said vesicle and being in a convenient configuration for conferring said virosome-like vesicle with an ability to induce an immune response against a gp41 protein or a human immunodeficiency virus (HIV). | 08-13-2009 |
20090232826 | Antibody or a fragment thereof, having neutralizing activity against hiv but not against il2 - The invention relates to a monoclonal antibody or a fragment thereof comprising in the H chain variable region at least one complementarity determining region (CDR) selected among CDR1, CDR2 and CDR3 having, respectively, an amino acids sequence set forth as SEQ ID NO 1, SEQ ID NO 2, SEQ ID NO 3 or functional analogues thereof. | 09-17-2009 |
20110311614 | SPLITTING GP41 - The present invention deals with a method for therapeutic or prophylactic treatment of HIV, in particular a prophylactic vaccinal method, comprising at least: administering to a patient a first antigen comprising the broadly neutralizing epitopes of the Membrane Proximal Ectodomain Region (MPER) of gp41, and administering to the same patient a second antigen comprising a modified polypeptide comprising three contiguous segments N, L and C represented by the formula N-L-C and comprising: a N-helix region of gp41(N), a C-helix region of gp41(C), and a connecting loop comprising a synthetic linker (L) between the N and C-helices, the linker replacing amino acids 593-617 of gp41, the numbering scheme being based upon the prototypic isolate HIV-1 HxB2 Clade B strain, said polypeptide comprising the calveolin-1 neutralizing and 98.6 D epitopes, but not 2F5 and 4E10 epitopes, not the fusion peptide, the polypeptide having a minimal immunogenic cross-reactivity with human interleukin 2. | 12-22-2011 |
20150051152 | PEPTIDE INCREASING FUSIOGENIC CAPACITY OF A GAMETE - The invention relates to a cyclic peptide increasing the fusiogenic capacity of the oocyte arising from the disintegrin loop of fertilin beta, to a pharmaceutical composition comprising said cyclic peptide and to the use thereof, particularly in order to supplement culture media used to carry out in vitro fertilization. | 02-19-2015 |
Patent application number | Description | Published |
20110117740 | METHOD FOR POLISHING HETEROSTRUCTURES - A polishing method for a heterostructure of at least one relaxed superficial heteroepitaxial layer on a substrate made of a different material. The method includes a first chemical mechanical polishing step of the surface of the heteroepitaxial layer performed with a polishing cloth having a first compressibility ratio and with a polishing solution having a first silica particle concentration. The first chemical mechanical polishing step is followed by a second chemical mechanical polishing step of the surface of the heteroepitaxial layer, with the second step being performed with a polishing cloth having a second compressibility ratio, higher than the first compressibility ratio, and with a polishing solution having a second silica particle concentration, lower than the first concentration. By this method, improved surface roughness is achieved. | 05-19-2011 |
20120280367 | METHOD FOR MANUFACTURING A SEMICONDUCTOR SUBSTRATE - The invention relates to a method for manufacturing a semiconductor substrate by providing a seed support layer and a handle support layer, forming at least one semiconductor layer, in particular of a Group III/V-semiconductor material, over the seed support layer, wherein the at least one semiconductor layer is in a strained state, forming a bonding layer over the at least one semiconductor layer, forming a bonding layer over the handle support layer, and bonding the seed and handle substrates together to obtain a donor-handle compound, by direct bonding between the bonding layer of the seed substrate and the bonding layer of the handle substrate. At least one of the bonding layer of the seed substrate and the bonding layer of the handle substrate includes a silicon nitride. | 11-08-2012 |
Patent application number | Description | Published |
20100209902 | Use of a Globin, a Globin Protomer or an Extracellular Hemoglobin for the Preservation of Organs, Tissues, Organ and Tissue Cells and Cell Cultures - The invention relates to the use of at least one globin and/or at least one globin protomer and/or at least one naturally extracellular native hemoglobin for the preservation of organs, tissues, organ and tissue cells and cell cultures. | 08-19-2010 |
20100234275 | Use Of A High Molecular Weight Extracellular Hemoglobin For The Manufacture Of A Medicament For Treating And/Or Preventing Diseases By Inhibition Of Calcium - The present invent ion relates to the use of a high molecular weight extracellular hemoglobin for the manufacture of a medicament for treating and/or preventing diseases by inhibition of calcium. Advantageously, the extracellular hemoglobin is obtained from Annelids. In particular, the invention concerns the use of a high molecular weight extracellular hemoglobin for the manufacture of a medicament for treating and/or preventing cardiovascular diseases, such as hypertension, angina such as angina pectoris, Raynaud's disease, arteriopathy, tachycardia, vasospasm, ischemia, myocardial infarct ion, congestive heart failure, arrhythmia or cerebrovacular accident. | 09-16-2010 |
20100278887 | Use of a Haemoglobin for the Preparation of Dressings and Resulting Dressings - The invention relates to the use of a haemoglobin for the preparation of dressings and to the resulting dressings. | 11-04-2010 |
20140113274 | ORGAN-PRESERVING COMPOSITION AND USES - The invention relates to the use of a composition comprising at least one globin, one globin protomer or one extracellular hemoglobin of Annelida, a stabilizing solution and/or a solution for conserving organs, said composition having a temperature of between 0° C. and 37° C., for preserving an organ in a donation after brain death donor or a donation after cardiac death donor. | 04-24-2014 |
20150190343 | ANNELID HAEMOGLOBIN LYOPHILISATION PROCESS - The present invention relates to a lyophilizate comprising at least one globin, one globin protomer or one extracellular hemoglobin of annelids, and a stabilizer chosen from disaccharides, polyols and antioxidants. The present invention also relates to a composition comprising: a solution comprising at least one globin, one globin protomer or one extracellular hemoglobin of annelids, and a stabilizer chosen from disaccharides, polyols and antioxidants. | 07-09-2015 |
Patent application number | Description | Published |
20110180089 | Container, a Device Including Such a Container, the Use of Such a Device, and a Method of Applying a Composition on the Nails - Container for receiving a composition, a device including such a container, a use and a method for applying the composition contained in such a container on the nails, the container comprising a side wall that extends along a central axis between a bottom and an opening, the side wall presenting a first outside constriction shaped to receive two adjacent fingers, other than the thumb, of a first hand of a user. The side wall also includes a second outside constriction shaped to receive two adjacent fingers, other than the thumb of a second hand of the same user, the second constriction being spaced apart from the first constriction along the central axis. | 07-28-2011 |
20130146078 | Container, a Device Including Such a Container, the Use of Such a Device and a Method of Applying a Composition on the Nails - Container for receiving a composition, a device including such a container, a use and a method for applying the composition contained in such a container on the nails, the container comprising a side wall that extends along a central axis between a bottom and an opening, the side wall presenting a first outside constriction shaped to receive two adjacent fingers, other than the thumb, of a first hand of a user. The side wall also includes a second outside constriction shaped to receive two adjacent fingers, other than the thumb of a second hand of the same user, the second constriction being spaced apart from the first constriction along the central axis. | 06-13-2013 |