Patent application number | Description | Published |
20120171161 | COMPOSITIONS COMPRISING PLACENTAL STEM CELLS AND PLATELET RICH PLASMA, AND METHODS OF USE THEREOF - Provided herein are compositions comprising placental stem cells and platelet rich plasma. Also provided herein are methods of treating an individual suffering from a disease or condition that would benefit from reduced inflammation, promotion of angiogenesis, and enhanced healing, comprising administering a therapeutically effective amount of a composition comprising placental stem cells and platelet rich plasma, as described herein, to said individual in an amount and for a time sufficient for detectable improvement of said disease or condition. | 07-05-2012 |
20120171180 | COMPOSITIONS COMPRISING AMNION DERIVED ADHERENT CELLS AND PLATELET-RICH PLASMA - Provided herein are methods of using amnion derived adherent cells, and populations of, and compositions comprising, such cells, in the modulation of an immune response. In various embodiments, the immune response is graft-versus-host disease, an allergy, asthma, or an immune-related disease or disorder, e.g., an autoimmune disease. | 07-05-2012 |
20150017140 | ORGANOIDS COMPRISING DECELLULARIZED AND REPOPULATED PLACENTAL VASCULAR SCAFFOLD - Provided herein are organoids comprising decellularized placental vascular scaffold comprising, or consisting of, a decellularized placental vascular scaffold, and methods of making and using the same. | 01-15-2015 |
20150017663 | IDENTIFICATION OF ANTITUMOR COMPOUNDS USING PLACENTA - Provided herein are methods of evaluating potential antitumor compounds, and thereby identifying antitumor compounds, using placenta or a portion thereof and tumor cells, and compositions for accomplishing the same. In one embodiment, provided herein is a method of determining whether a potential antitumor compound is effective against a plurality of tumor cells, comprising introducing a plurality of tumor cells to, e.g., into or onto, a mammalian placenta or portion thereof; contacting said plurality of tumor cells for a period of time with said antitumor compound; and determining whether said antitumor compound is effective against said tumor cells, wherein said antitumor compound is effective against said tumor cells if said antitumor compound over said period of time reduces the number of said tumor cells or reduces the growth rate of said tumor cells. | 01-15-2015 |
20150224226 | METHODS OF TISSUE GENERATION - Provided herein are methods of generating tissues and organs in vitro or ex vivo comprising depositing cells and extracellular matrix onto a surface, as well as methods of using such tissues and organs. In one embodiment, the cells and ECM used in accordance with the methods for generating tissues (e.g., three-dimensional tissues) and organs described herein are deposited as part of the same composition. In another embodiment, the cells and ECM used in accordance with the methods for generating tissues (e.g., three-dimensional tissues) and organs described herein are deposited as part of different compositions. | 08-13-2015 |
20150246072 | METHODS OF TISSUE GENERATION - Provided herein are methods for forming three-dimensional tissues in vivo. In one embodiment, provided herein is a method for forming a three-dimensional tissue in vivo, comprising depositing on a surface that is in or on a subject at least one composition that comprises cells. In another embodiment, provided herein is a method for forming a three-dimensional tissue in vivo, comprising depositing on a surface that is in or on a subject at least one composition that comprises cells and at least one composition that comprises an extracellular matrix (ECM). In another embodiment, provided herein is a method for forming a three-dimensional tissue in vivo, comprising depositing on a surface that is in or on a subject at least one composition that comprises cells, at least one composition that comprises an extracellular matrix (ECM), and at least one other additional components. | 09-03-2015 |
20150313948 | TREATING ORAL LESIONS USING PLACENTAL EXTRACELLULAR MATRIX - Provided herein are uses of compositions comprising extracellular matrix (ECM) and compositions comprising ECM components in the treatment of non-dental oral lesions. | 11-05-2015 |
20160030635 | IMPROVED METHOD OF MAKING EXTRACELLULAR MATRIX COMPOSITIONS - Provided herein are methods of producing extracellular matrix (ECM) that are superior to previously-described methods. Extracellular matrix (ECM) comprises protein that forms many structures in the body including tendons, ligaments, and sheets that support skin and internal organs. There remains a need in the art for ECM compositions that have improved cell attachment characteristics and methods of making such ECM compositions. | 02-04-2016 |