Patent application number | Description | Published |
20100195048 | Adaptive Optics Line Scanning Ophthalmoscope - A first optical module scans a portion of an eye with a line of light, descans reflected light from the scanned portion of the eye and confocally provides output light in a line focus configuration. A detection device detects the output light and images the portion of the eye. A second optical module detects an optical distortion and corrects the optical distortion in the line of light scanned on the portion of the eye. | 08-05-2010 |
20110234978 | Multi-functional Adaptive Optics Retinal Imaging - An optical apparatus includes a system of optical components capable of operating in a scanning laser ophthalmoscope (SLO) mode and an optical coherence tomography (OCT) mode. The system of optical components includes a first optical module for the SLO mode, a second optical module for the OCT mode, and a first scanning device. The first optical module for the SLO mode includes a first source adapted to provide a first imaging beam for the SLO mode and a first detection device configured to receive a first signal associated with a first image of a retina of an eye. The second optical module for the OCT mode includes a second source adapted to provide a second imaging beam for the OCT mode and a second detection device configured to receive a second signal associated with a second image of the retina. The first scanning device is configured to move the first imaging beam along the retina in the slow axis of the SLO mode to acquire the first image and (ii) to move the second imaging beam along the retina in the fast axis of the OCT mode to acquire the second image. | 09-29-2011 |
20120101390 | Multi-Modal Imaging for Diagnosis of Early Stage Epithelial Cancers - Epithelial cancer screening can include a staining tissue with a cancer targeting agent, identifying a potentially cancerous lesion using fluorescence imaging, and imaging the potentially cancerous lesion for a cancer diagnosis using optical coherence tomography. | 04-26-2012 |
20120294328 | Optical Coherence Tomography (OCT) Freeze Drying Microscopy - A product critical temperature during freeze drying is determined. The product is imaged using optical coherence tomography (“OCT”). The product is freeze dried while the temperature of the product is measured. The product critical temperature is the temperature at which a product structure event occurs during freeze drying. | 11-22-2012 |
20130229620 | Enhanced Sensitivity Line Field Detection - A retinal imaging device includes an optical system configured to (i) scan a portion of the retina of the eye with a line of light, (ii) descan reflected light from the scanned portion of the retina, and (iii) provide output light in a line focus configuration. The device includes a detection device including a linear array of asymmetric pixels having at least a 2:1 ratio of length to width, a detection device with multiple adjacent linear arrays, and/or a detection device using a time delay and integration (TDI) architecture. | 09-05-2013 |
20140031677 | Apparatus and Method for Aiding Needle Biopsies - A handheld optical coherence tomography imaging and tissue sampling system and method of imaging and sampling a tissue is disclosed. The method includes inserting a catheter probe into a biopsy needle. The biopsy needle can be attached to a hand-held scanning and sampling device. The biopsy needle is maneuvered to an investigation site. A three-dimensional image of the tissue at the investigation site is captured with the catheter probe. | 01-30-2014 |
20140213897 | Combined Reflectance Confocal Microscopy-Optical Coherence Tomography System for Imaging of Biological Tissue - A dual-modality apparatus for imaging of biological tissue includes a reflectance confocal microscopy (RCM) imaging apparatus and an optical coherence tomography (OCT) imaging apparatus. A first optical component reflects a first beam of light provided by a RCM imaging apparatus towards a sample and passes a second beam of light provided by an OCT imaging apparatus towards the sample, such that the first and second beam of lights share at least a portion of an imaging path. | 07-31-2014 |
20140247425 | Multi-Functional Adaptive Optics Retinal Imaging - An optical apparatus includes a system of optical components capable of operating in a scanning laser ophthalmoscope (SLO) mode and an optical coherence tomography (OCT) mode. The system of optical components includes a first optical module for the SLO mode, a second optical module for the OCT mode, and a first scanning device. The first optical module for the SLO mode includes a first source adapted to provide a first imaging beam for the SLO mode and a first detection device configured to receive a first signal associated with a first image of a retina of an eye. The second optical module for the OCT mode includes a second source adapted to provide a second imaging beam for the OCT mode and a second detection device configured to receive a second signal associated with a second image of the retina. The first scanning device is configured to move the first imaging beam along the retina in the slow axis of the SLO mode to acquire the first image and (ii) to move the second imaging beam along the retina in the fast axis of the OCT mode to acquire the second image. | 09-04-2014 |
20140268040 | Multimodal Ocular Imager - An imaging probe for imaging a sample includes at least one light source that provides light to a sample. The imaging probe also includes a first imaging objective that focuses a first light reflected from the sample and a second light reflected from the sample, such that the first light and the second light share at least a portion of an imaging path. The imaging probe also includes a first optical component that receives the first light and the second light from the first imaging objective, directs the first light towards an imaging camera to obtain a first image of the sample, and directs the second light toward an optical coherence tomography (OCT) imaging apparatus to obtain a second image of the sample. | 09-18-2014 |
20150063406 | Optical Coherence Tomography (OCT) Freeze Drying Microscopy - A product critical temperature during freeze drying is determined. The product is imaged using optical coherence tomography (“OCT”). The product is freeze dried while the temperature of the product is measured. The product critical temperature is the temperature at which a product structure event occurs during freeze drying. | 03-05-2015 |