Mcdonald, GB
Alan Mcdonald, Antrim GB
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20130146587 | THERMAL STORAGE DEVICE CONTROLLER - A controller providing selective activation of thermal storage devices within a network to balance requirements of a user to manage their heating and the network operator to balance the load available with the load on the network. | 06-13-2013 |
Alan Mcdonald, Lisburn GB
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20150055941 | THERMAL STORAGE DEVICE - An improved thermal store is provided. The thermal decouples the heat output from the thermal store from the energy provided to the heater. | 02-26-2015 |
Alasdair Stewart Mcdonald, Edinburgh GB
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20100213787 | MAGNETIC FLUX CONDUCTING UNIT - The present invention relates to a magnetic flux conducting unit ( | 08-26-2010 |
20140062238 | MODULAR ELECTRICAL MACHINE - A modular electrical machine includes multiple integrated rotor modules releasably mounted upon a power transmission member to form a torus-like structure, wherein each integrated rotor module includes a series of parallel rotor plates spaced apart to provide an air gap between successive rotor plates in the series. The rotor plates hold permanent magnets securely within the air gap. Corresponding stator modules, each made of multiple air-cored coils potted in a resin material to form a blade. Each blade is externally supported with respect to the rotor module and is positioned between the permanent magnets within one of the air gaps between successive rotor plates. | 03-06-2014 |
Andrew Mcdonald, Hampshire GB
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20100014483 | Network Selection - A wireless user device, in radio communication with a first access point of one or more networks with which it could communicate via at least one of a plurality of access points, sends a network selection request to the first access point. If the network wishes to initiate a response from another access point in the same or another network, the first access point forwards the network selection request to one or more neighboring access points, in the same or another network. If any of the neighboring access points is able to communicate with the user device, that neighboring access point sends a response directly to the wireless user device and the wireless user device chooses the most suitable network from the responses sent. | 01-21-2010 |
Andrew Mcdonald, Romsey GB
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20130064222 | NETWORK SELECTION - A wireless user device, in radio communication with a first access point of one or more networks with which it could communicate via at least one of a plurality of access points, sends a network selection request to the first access point. If the network wishes to initiate a response from another access point in the same or another network, the first access point forwards the network selection request to one or more neighboring access points, in the same or another network. If any of the neighboring access points is able to communicate with the user device, that neighboring access point sends a response directly to the wireless user device and the wireless user device chooses the most suitable network from the responses sent. | 03-14-2013 |
Andrew Derek Mcdonald, Romsey GB
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20120218999 | Method and Apparatus for Identifier Correlation - A method of identifier correlation in a communications network, the network comprising: an identifier translator, for translating at least one identifier of a communications packet, wherein a packet which has passed through the identifier translator comprises translated and untranslated identifiers; the method comprising: | 08-30-2012 |
Barry David Mcdonald, Glasgow GB
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20110131496 | SELECTION OF CONTENT TO FORM A PRESENTATION ORDERED SEQUENCE AND OUTPUT THEREOF - A method of selecting content to form a content presentation, the presentation comprising an ordered sequence of selected amounts of content, there being a plurality of items of content available for the presentation, the method comprising: (a) for each of the items of content, determining an associated weight-value based, at least in part, on one or more parameters for the presentation; (b) performing a weighted selection of one of the items of content, the selection being weighted in accordance with the weight-values associated with the items of content; (c) selecting at least a part of the content of the selected item of content to be one of the amounts of content in the ordered sequence of selected amounts of content; and (d) repeating steps (a), (b) and (c) until the presentation is complete. | 06-02-2011 |
Clive Richard Mcdonald, Chester Cheshire GB
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20130000583 | LIQUID FUEL COMPOSITIONS - The present invention provides a liquid fuel composition comprising:—a base fuel suitable for use in an internal combustion engine; and—one or more polyetheramines having formula (I): wherein R is an —NR | 01-03-2013 |
20130000584 | LIQUID FUEL COMPOSITIONS - The present invention provides a method of improving the performance of the lubricant of an internal combustion engine, said method comprising fuelling an internal combustion engine containing the engine lubricant with a liquid fuel composition comprising:—a base fuel suitable for use in an internal combustion engine; and—one or more poly (hydroxycarboxylic acid) derivative having a terminal amine group having formula (III): [Y—CO[O-A-CO] | 01-03-2013 |
Craig Mcdonald, Aberdeen GB
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20150027730 | WELL TREE HUB AND INTERFACE FOR RETRIEVABLE PROCESSING MODULES - The present disclosure relates to providing a hub coupled into a production tree, manifold, or other equipment, and a base module that is attachable to and retrievable from the hub. The base module may be reconfigurable. The base module may be configured to receive other modules that are reconfigurable, wherein the other modules are retrievable from the base module. The hub provides a dedicated space or support at or near the production tree or equipment for using the base module. An interface is provided between the base module and the production tree. A fluid conduit provides a fluid path across or through the interface. The hub may be part of the interface such that the module can fluidly couple to the fluid conduit and the production tree across the interface via the hub. | 01-29-2015 |
David Mcdonald, Newton Aycliffe County Durham GB
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20150051603 | HARDENABLE TWO PART ACRYLIC COMPOSITION - A hardenable two part acrylic composition is described for the treatment of human or animal bone is described. The composition comprises a storage stable liquid first part and a storage stable liquid second part which react with each other upon mixing to form a cement which hardens. The composition further comprises an acrylic monomer component and an initiator component in an amount effective to polymerize the monomer component. The monomer component and the initiator component are generally located in separate parts of the two part composition so that the monomer component is storage stable. The liquid first part comprises emulsion polymerized acrylic polymer particles in a liquid carrier. A method of producing a hardenable two part acrylic composition is also described. The composition is particularly useful in a syringe or caulking gun having at least two barrels. | 02-19-2015 |
David Mcdonald, Country Durham GB
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20110263739 | HARDENABLE TWO PART ACRYLIC COMPOSITION - A hardenable two part acrylic composition, a polymer component of the two part hardenable composition and a method of producing a polymer component of the two part composition are disclosed. The hardenable two part acrylic composition includes an acrylic polymer composition first part and an acrylic monomer composition second part. The acrylic polymer composition first part includes a first type of acrylic polymer particles wherein each first type of acrylic polymer particle is formed of a network of coalesced emulsion polymerized acrylic microparticles or is microporous. The acrylic polymer composition may include emulsion polymerised acrylic polymer particles of particle size between 10 and 2000 nm and includes the use of acrylic polymer particles formed of a network of coalesced emulsion polymerized acrylic microparticles as a dough time reduction agent in a hardenable two part acrylic composition. | 10-27-2011 |
Donald Farquhar Mcdonald, London GB
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20100184213 | APOCRINE CELL LINE - An apocrine cell line is obtained by the steps of isolating an apocrine cell from primary tissue, culturing the isolated cell in a first culture medium, removing unattached cells from the first culture medium and transferring said unattached cells to a second culture medium comprising an effective concentration of a phorbol ester, and thereby establishing an apocrine cell line exhibiting long-term proliferation capability, which after many cultures is indicative of indefinite proliferation. | 07-22-2010 |
Gary Peter Mcdonald, Glasgow GB
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20140114392 | METHOD AND APPARATUS FOR CONTROLLING THE DEPLOYMENT OF A STENT - A control system for deploying a stent graft ( | 04-24-2014 |
20140114393 | STENT ELEMENT - There is provided a stent element comprising a central portion with two arms extending therefrom, optionally in a V-shaped or Y-shaped configuration. The arms of the stent-element are resiliently deformable to facilitate packing and suitable material for forming the stent-element is nitinol or PEEK. The stent element can be used to stabilise two adjacent ring stents on a stent graft by attachment to the graft material between the ring stents, for example by sewing. The stent element stabilises the ring stent without risk of fracture. A stent graft having two ring stents and the stent element located between the ring stents is also described. | 04-24-2014 |
20140121761 | STENT AND STENT GRAFT PROSTHESIS - There is provided a stent member a plurality of spaced stent elements for location on a tubular graft, wherein a first stent element is located in a first location on said graft, and wherein a second stent element is located in a second location or said graft, and wherein the second stent element comprises a saddle shaped stent. The first stent element includes a ring shaped (circular) stent. The second stent element includes at least one, preferably 2 to 5, saddle shaped stents. Optionally a third stent element comprising from 1 to 10 saddle shaped stents is also present. The stents are typically form a continuous loop of an elongate member of resilient material such as nitinol or PEEK. A stent graft comprising a tubular sleeve to which the stent member is attached is also described, as is the use of the prosthesis for treatment of vascular disorders such as aortic aneurysm. | 05-01-2014 |
George Mcdonald, Castel GB
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20120067962 | FOLDED SHEET ARTICLE AND METHOD OF MANUFACTURING THE SAME - A folded sheet article comprising a sheet material having a first set of folds defining segments of the sheet material and an electrically conductive pattern on a segment of the sheet material that does not extend across a fold in an unfolded state. | 03-22-2012 |
George Wallace Mcdonald, Channel Islands GB
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20100148486 | Sheet articles - The invention provides a sheet article comprising a cover ( | 06-17-2010 |
20150306896 | APPARATUS FOR, AND METHOD OF, MANUFACTURE OF A FOLDED-SUBSTRATE ARTICLE - A method and apparatus are provided for the manufacture of an article made up of a number of elements, including a resilient element, that are bonded together during the manufacturing process. The apparatus incudes a guide track which defines a path along which the elements travel during the manufacturing process and a compression frame provided along at least part of the length of the track for compressing the resilient element as the resilient member travels along the path defined by the guide track. The process includes moving a combination of article precursor elements together along the guide track rails such that the compression frame acts to press the elements together during bonding. The method and apparatus minimize misalignment of the elements and thereby improve quality of the finished article as well increasing production rates compared to conventional methods and apparatus. | 10-29-2015 |
Gregor J. Mcdonald, Malvern GB
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20090034969 | CORRELATION APPARATUS - This invention relates to a pattern recognition correlator in which a serial input data signal is converted into a parallel data signal for correlation with one or more reference data signals. The invention relates to use of a demultiplexer in such a correlation apparatus to reduce the data update rate for the subsequent components. The invention also relates to the use of a series of latch circuits to provide serial to parallel conversion of the input data signal in the electrical domain. | 02-05-2009 |
Gregor John Mcdonald, Malvern GB
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20100027087 | IMPROVEMENTS TO OPTICAL CORRELATION APPARATUS - An optical correlation apparatus is taught which provides a parallel optical signal having a phase modulation representing input data to which a parallel phase modulation based on reference data is applied. In the event of correlation the resulting wavefront is planar and can be interferometrically coupled to give a high intensity signal. The invention involves use of parallel amplitude modulation means for selectively blocking the optical signal in one or more of the channels of the parallel optical signal which allows different sized reference data strings to be searched more easily and also aids in calibration. | 02-04-2010 |
Gregor John Mcdonald, Upton Upon Severn GB
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20100002281 | OPTICAL CLOCK - An optical clock comprises a laser oscillator and modulating means arranged to cooperate with the laser oscillator to produce a series a series of phase-modulated optical pulses. The optical clock further comprises an optical fibre arranged to provide compression of the optical pulses, and may also comprise a step-recovery diode arranged to pulse-pick pulses output from the fibre to produce a series of optical clock pulses, depending on the mode of operation of the modulating means. Phase-modulation is carried out a frequency which provides sufficient linewidth broadening to inhibit stimulated Brillouin scattering within the optical fibre. An optical clock of the invention provides a robust and reliable alternative to clocks based on modelocked lasers, and may be assembled from inexpensive, commonly-available components. The repetition rate of a clock of the invention may easily be adjusted by electronic means. Unlike many modelocked lasers, a clock of the invention does not require precise optical alignment. | 01-07-2010 |
20110116687 | METHOD AND APPARATUS FOR OBJECT CLASSIFICATION - A method of classifying an object, in particular of classifying a vehicle by evaluating the degree of correlation between an image data set corresponding to an image of at least part of the vehicle and each of a plurality of reference data sets each of which corresponds to a reference image of a vehicle comprises the steps of establishing the vehicle's aspect and selecting the plurality of reference data sets from a larger group of such data sets on the basis of the vehicle's aspect. By selecting from the larger group only those reference data sets which correspond to the vehicle's aspect, faster classification is achieved for a given level of processing resources. Alternatively, for a given processing or classification rate, the level of processing resources may be reduced compared to the prior art. | 05-19-2011 |
Gregor John Mcdonald, Worcestershire GB
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20100265491 | RANGE-FINDING METHOD AND APPARATUS - Range-finding apparatus comprises a source of pulsed radiation of variable repetition rate and a beam-splitter for dividing the pulsed radiation into two portions which are directed respectively to a local retro-reflector and to a retro-reflector co-located with a remote target the range of which is to be determined. The source, beam-splitter and retro-reflectors are arranged in the form of Michelson interferometer together with a detector. The repetition rate of the source is tuned to frequencies f such that round-trip distance to the remote target is mc/f where m is an integer, this condition being detected by observing a heterodyne signal at the detector. Two such frequencies enable range to be determined. The precision with which range is determined may be increased by carrying out interferometry using the two portions. The accuracy of the method does not depend on absolute range (as with triangulation) and is not limited by the speed of timing electronics, as is the case for time-of-flight techniques. | 10-21-2010 |
Gregor John Mcdonald, Upton-On-Severn GB
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20110002029 | OPTICAL CLOCK - An optical clock for generating a series of optical clock pulses, comprises a laser source for generating output having a plurality of spectral components λ | 01-06-2011 |
James Mcdonald, East Sussex GB
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20120239859 | APPLICATION PROFILING IN A DATA STORAGE ARRAY - Method and apparatus for application profiling in a multi-device data storage array. In accordance with various embodiments, a storage array is formed of independent data storage devices that form a fast pool and a slow pool of said devices, such as solid-state drives (SSDs) and hard disc drives (HDDs). A controller is adapted to migrate a distributed data set stored across a first plurality of the devices in the slow pool to a second plurality of said devices in the fast pool. The controller carries out the migration responsive to a hint that a selected application is about to be executed that utilizes the distributed data set, and responsive to a return on investment (ROI) determination that an estimated cost of said migration will be outweighed by an overall improved data transfer capacity of the storage array over a predetermined minimum payback period of time. | 09-20-2012 |
James C. Mcdonald, Suffolk GB
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20110010312 | COMMUNICATIONS NETWORK - A multi-use service charging protocol is disclosed. A data structure ( | 01-13-2011 |
James Peter Mcdonald, Aberdeen GB
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20120189472 | POWER UNIT - A hydraulic power unit for subsea use is disclosed. The power unit includes a housing containing a fluid, an electric motor mounted in the housing, a distribution pump, a heat exchange unit provided externally to the housing and at least one distribution conduit in fluid communication with the heat exchange unit and the housing. | 07-26-2012 |
James R. Mcdonald, Stewarton GB
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20110264398 | Fibre Optic Sensor System - A combined pressure and temperature sensor, the sensor comprising at least one first optical sensing element of a first type and at least one second optical sensing element of a second type, wherein the sensor is adapted to compensate for temperature and/or pressure effects in the first or second optical sensing element using a response of the other of the second or first optical sensing elements. | 10-27-2011 |
Jennifer Laura Mcdonald, Henleaze GB
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20120216670 | ARMOUR - There is disclosed armour having an outer metallic layer, an inner fibre composite layer, and a supporting framework between the inner and outer layers. The supporting framework can include projections from the outer layer arranged to mechanically interlock with the fibres of the fibre composite, and can be arranged to provide an open region between the inner and outer layers that can be filled with a functional filler material. | 08-30-2012 |
Jennifer Laura Mcdonald, Avon GB
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20100207299 | METHODS OF FABRICATING STRUCTURAL ELEMENTS - A method of fabricating structural elements on the surface of a component is provided. The structural elements are configured to modify flow of a fluid passing over the surface. Conveniently, the fabrication is performed using a Direct Write technique. A three dimensional element is formed by depositing material on the surface, and subsequently curing the deposited material. | 08-19-2010 |
Jennifer Laura Mcdonald, Bristol GB
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20100171792 | Direct Write and Additive Manufacturing Processes - A Direct Write method of forming components on a substrate by deposition of ink by thermally curing the ink in situ, which method overcomes the need for curing by placing the substrate in an oven. The curing is performed in an exemplary embodiment using an induction coil ( | 07-08-2010 |
Ken Mcdonald, Oxford GB
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20130096699 | ASSET HEALTH MONITORING - A machine management system, including one or more sensors arranged to take readings of one or more operating variables for a machine. Data processing equipment is arranged to receive data indicative of said operating variable readings for the machine and to analyse the received operational data to determine a probability distribution there-for. The processing equipment includes one or more modules of machine-readable code for assigning a value to one or more Stable distribution parameters in dependence on the received operational data, and a departure in the machine operation from a predetermined normal operating condition is determined from the assigned distribution parameter. | 04-18-2013 |
Kenneth Mcdonald, Leeds Yorkshire GB
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20100251990 | Engine - An engine comprising a first section having a first face and a second section having a second face, the first and second faces being opposed to one another and arranged for relative rotation, the first face comprising at least one chamber, the second face comprising a plurality of discrete regions each being associated with a discrete stage of a combustion cycle, wherein the first and second faces are arranged such that relative rotation thereof causes the at least one chamber of the first face to be exposed to the discrete regions of the second face. | 10-07-2010 |
Lee Mcdonald, Nottinghamshire GB
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20140191964 | Headset Computer with Head Tracking Input Used For Inertial Control - A Head-tracker is built into a headset computer as a user input device. A user interface navigation tool utilizes the head tracking but with inertial control. The navigation tool is formed of two different sized circles concentrically depicted, and a pointer. The pointer is moveable within the two circles defining inner and outer boundaries. The pointer represents user's head position and movement sensed by the head tracker. The HSC displays a document and pans (navigates) the document as a function of user head movement sensed by the head tracker and illustrated by the navigation tool. The direction of movement of the pointer depicted in the navigation tool defines pan direction of the displayed document. Pan speed of the displayed document is defined based on position of the pointer, with respect to the inner and outer circle boundaries in the navigation tool. | 07-10-2014 |
Lynn Mcdonald, Bristol GB
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20090127406 | AILERON ACTUATOR BRACKET - An aircraft wing comprising: a trailing edge cove extending in a span-wise direction along a trailing edge of the wing, the trailing edge cove having a front face, a top face and a bottom face; an actuator bracket which is mounted to the front and top faces of the trailing edge cove, but not to its bottom face; an aileron actuator coupled at one end to an aileron and at the other end to the actuator bracket, the aileron actuator being adjustable from a retracted position to a deployed position to deploy the aileron; and a channel extending in a span-wise direction along the wing and positioned below the actuator bracket. | 05-21-2009 |
Michael Mcdonald, Surrey GB
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20100124534 | IMMUNOTHERAPEUTIC METHOD - The present invention provides a method of monitoring the efficacy of an immunotherapy in a mammalian subject, wherein the subject has been administered an immunotherapy, wherein the immunotherapy comprises a viral vector containing a polynucleotide encoding an antigen, wherein the viral vector is capable of transducing cells in the mammalian subject to cause the cells to express the antigen; the method comprising: | 05-20-2010 |
Neil Mcdonald, Staffordshire GB
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20130125666 | VARIABLE TORQUE RATE TEST JOINT - In a variable torque rate test joint, screw-threaded first and second elements are rotated relative to one another by a tool under test. At least one spring beam is cantilevered over a pivot point to exert an axial force between the first and second elements and the torque rate of the test joint can be varied by moving the pivot point to change the axial force. The first element may be a shaft that is fixed during testing and the second element is a nut rotatably mounted on the shaft, whereby the element rotated by the tool has a minimal moment of inertia. Whichever of the first and second elements is held stationary during the test may be mounted in a hub that is locked during the test but can be rotated at the end of the test to reset the test joint. Measurements may be made of the torque and the rotation angle to derive an actual torque rate of the joint, which allows correction of errors by moving the pivot point. | 05-23-2013 |
Neil Mcdonald, Edinburgh GB
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20140134110 | OPTICAL IMAGING PROBES - The present invention relates to methods of visualising cells especially although not exclusively in vivo using a dye, such as a dendrimer-dye molecule or polybranched-dye molecule which is internalised by the cells and thus permits subsequent visualisation by confocal fluorescence endomicroscopy or other optical detectors. There is also provided internally quenched probes for use in visualising cells especially although not exclusively in vivo by confocal fluorescence endomicroscopy and the use of internally quenched probes in combination with confocal fluorescence endomicroscopy, for visualising cells by virtue of internalisation and dequenching of a probe by the cells. In a particular embodiment the cells are activated neutrophils, such as within the lung of a subject. | 05-15-2014 |
Nick Mcdonald, Edinburgh GB
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20110005832 | OFFSHORE THERMAL TREATMENT OF DRILL CUTTINGS FED FROM A BULK TRANSFER SYSTEM - A system for offshore disposal of drill cuttings including a cleaning system for treating contaminated drill cuttings into drill cuttings and contaminants; a transport system for moving the drill cuttings; a slurrification system for making a slurry of the treated drill cuttings; and a cuttings re-injection system for injecting the slurry into a well. | 01-13-2011 |
Nick Mcdonald, Stonehaven GB
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20080210466 | OFFSHORE THERMAL TREATMENT OF DRILL CUTTINGS FED FROM A BULK TRANSFER SYSTEM - A system for offshore treatment of drill cuttings that includes a first pressurized vessel configured to receive contaminated drill cuttings and adapted to allow a compressed gas be introduced therein as the sole means for inducing movement of said contaminated drill cuttings in the first pressurized vessel whereby at least a portion of the contaminated drill cuttings is discharged from the first pressurized vessel; and a reactor unit in fluid connection with the first pressurized vessel for separating the contaminated drill cuttings into drill cuttings and contaminants, wherein the reactor unit includes a processing chamber having at least one inlet and outlet; and a rotor mounted in the processing chamber, the rotor including a shaft; and a plurality of fixed rotor arms extending radially from the shaft is disclosed. | 09-04-2008 |
Paul Mcdonald, Swindon GB
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20080268840 | Apparatus and Method for Controlling a Radio Bearer Reconfiguration - An apparatus for controlling a radio bearer reconfiguration in a cellular communication system, such as a UMTS communication system, comprises a reconfiguration instigator ( | 10-30-2008 |
Philip Mcdonald, Yorkshire GB
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20150375491 | APPARATUS AND METHOD FOR PRODUCING A LAMINATE - An apparatus ( | 12-31-2015 |
Simon Mcdonald, Zug GB
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20090182712 | Systems and methods for rapid delivery of media content - In one embodiment of the present invention, a system is provided that includes at least one computer for receiving from a user a search query that includes at least one search term. A first portion of a set of data that includes the first portion and a second portion of data, is transmitted from a first source. The computer determines whether or not to transmit at least a portion of the set of data to the user from a second source based upon the presence of the at least one search term within only the second portion of the set of data. | 07-16-2009 |
Thomas Oliver Mcdonald, Liverpool GB
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20140212501 | COMPOSITIONS OF LOPINAVIR - The present invention relates to a solid composition and an aqueous dispersion comprising nanoparticles of the anti-retroviral drug lopinavir. The solid composition and aqueous dispersion additionally comprise a mixture of a hydrophilic polymer and a surfactant. The surfactant is selected from vitamin-E-polyethylene glycol-succinate (Vit-E-PEG-succinate), a polyoxyethylene sorbitan fatty acid ester, N-alkyldimethylbenzylammonium chloride, sodium deoxycholate, dioctyl sodium sulfosuccinate, polyethyleneglycol-12-hydroxystearate, polyvinyl alcohol (PVA), and a block copolymer of polyoxyethylene and polyoxypropylene, or a combination thereof. The hydrophilic polymer is suitably selected from polyvinyl alcohol (PVA), a polyvinyl alcohol-polyethylene glycol graft copolymer, a block copolymer of polyoxyethylene and polyoxypropylene, polyethylene glycol, hydroxypropyl methyl cellulose (HPMC), and polyvinylpyrrolidone, or a combination thereof. The present invention also relates to processes for preparing both the solid composition and the aqueous dispersion, as well as to their use in therapy for the treatment and/or prevention of retroviral infections such as human immunodeficiency virus (HIV). | 07-31-2014 |
20140220140 | COMPOSITIONS OF EFAVIRENZ - The present inventions relates to a solid composition and an aqueous dispersion comprising nanoparticles of the anti-retroviral drug efavirenz. The solid composition and aqueous dispersion additionally comprise a mixture of a hydrophilic polymer and a surfactant. The surfactant is selected from vitamin-E-polyethylene glycol-succinate (Vit-E-PEG-succinate), a polyoxyethylene sorbitan fatty acid ester, N-alkyldimethylbenzylammonium chloride, sodium deoxycholate, dioctyl sodium sulfosuccinate, polyethyleneglycol-12-hydroxystearate, polyvinyl alcohol (PVA), and a block copolymer of polyoxyethylene and polyoxypropylene, or a combination thereof. The hydrophilic polymer is suitably selected from polyvinyl alcohol (PVA), a polyvinyl alcohol-polyethylene glycol graft copolymer, a block copolymer of polyoxyethylene and polyoxypropylene, polyethylene glycol, hydroxypropyl methyl cellulose (HPMC), and polyvinylpyrrolidone, or a combination thereof. The present invention also relates to processes for preparing both the solid composition and the aqueous dispersion, as well as to their use in therapy for the treatment and/or prevention of retroviral infections such as human immunodeficiency virus (HIV). | 08-07-2014 |
20140220141 | COMPOSITIONS OF LOPINAVIR AND RITONAVIR - The present inventions relates to a solid composition and an aqueous dispersion comprising nanoparticles of the anti-retroviral drugs lopinavir and ritonavir. The solid composition and aqueous dispersion additionally comprise a mixture of a hydrophilic polymer and a surfactant. The surfactant is selected from vitamin-E-polyethylene glycol-succinate (Vit-E-PEG-succinate), a polyoxyethylene sorbitan fatty acid ester, N-alkyldimethylbenzylammonium chloride, sodium deoxycholate, dioctyl sodium sulfosuccinate, polyethyleneglycol-12-hydroxystearate, polyvinyl alcohol (PVA), and a block copolymer of polyoxyethylene and polyoxypropylene, or a combination thereof. The hydrophilic polymer is suitably selected from polyvinyl alcohol (PVA), a polyvinyl alcohol-polyethylene glycol graft copolymer, a block copolymer of polyoxyethylene and polyoxypropylene, polyethylene glycol, hydroxypropyl methyl cellulose (HPMC), and polyvinylpyrrolidone, or a combination thereof. The present invention also relates to processes for preparing both the solid composition and the aqueous dispersion, as well as to their use in therapy for the treatment and/or prevention of retroviral infections such as human immunodeficiency virus (HIV). | 08-07-2014 |
Tony Mcdonald, Romsey GB
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20140232585 | OBJECT DETECTOR - An object detector comprising: a transmitter arranged to generate a transmit signal; a transmit loop antenna, coupled to said transmitter and arranged to radiate said transmit signal; and a receive loop antenna arranged to generate a receive signal from received radio waves; wherein said received radio waves include said radiated transmit signal and, in the presence of objects within range of the device which reradiate said transmit signal, one or more radio waves reradiated by such objects; said receive signal includes a component corresponding to said transmit signal and, in the presence of reradiated radio waves, one or more components corresponding to said reradiated radio waves; and said object detector further comprises a signal detector, coupled to said receive loop antenna and said transmitter, the signal detector arranged to detect changes in the amplitude and/or phase of said receive signal which are due to changes in said components corresponding to said reradiated radio waves. | 08-21-2014 |