Matteucci
Andrea Matteucci, Esslingen DE
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20140230523 | DEVICE AND METHOD FOR MEASURING THE PARTICLE CONCENTRATION IN AN AEROSOL - A device for measuring the particle concentration in an aerosol using a flow tube includes a cavity in which there is a sleeve, the cavity branching off from the flow tube. The sleeve includes, at its end facing away from the flow tube, a collar. The collar encircles the periphery of the sleeve and is fastened at the periphery of the cavity. There is one or more inflow openings in the collar. At least one outflow opening is in an end of the sleeve, which end extends into the flow tube. A measuring chamber is also included in the cavity on the side of the sleeve facing away from the flow tube. | 08-21-2014 |
Andrea Matteucci, Stuttgart DE
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20150077749 | DEVICE FOR CALIBRATING A SCATTEROMETER - A calibration device is described for calibrating a scatterometer, which is designed in particular for measuring a particle concentration in exhaust gases of motor vehicles. The calibration device has at least one scattering body which emits scattered light having a defined intensity and distribution when irradiated with a light beam, the scattering body having an emission surface for the scattered light, to which is assigned at least one light sensor for detecting the scattered light exiting the emission surface. A screening body having at least one screen opening through which the scattered light exits in the direction of the at least one light sensor is assigned to the emission surface of the scattering body. | 03-19-2015 |
20150128688 | METHOD FOR DETECTING A DEVIATION OF A COMPRESSION PRESSURE OF ONE CYLINDER FROM THAT OF ANOTHER CYLINDER OF AN INTERNAL COMBUSTION ENGINE - In a method for detecting a deviation of a compression pressure of one cylinder from that of another cylinder of an internal combustion engine having at least two cylinders, the rotational speed of a crankshaft of the internal combustion engine is reduced from a starting rotational speed to a target rotational speed; the actual rotational speed is detected; a curve of a change of the actual rotational speed per angle unit of the crankshaft is determined as a curve of a rotational speed gradient; the curve of the rotational speed gradient is subjected to order analysis; and a deviation of the compression pressure of one cylinder from that of another cylinder is detected when an amplitude of a selected order lies above a permissible threshold value. | 05-14-2015 |
Mizio Matteucci, Essex GB
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20120077815 | Fused Pyridine And Pyrazine Derivatives As Kinase Inhibitors - A series of amino-substituted fused pyridine and pyrazine derivatives, in particular amino-substituted quinoline and quinoxaline derivatives, being selective inhibitors of PI3 kinase enzymes, are accordingly of benefit in medicine, for example in the treatment of inflammatory, autoimmune, cardiovascular, neurodegenerative, metabolic, oncological, nociceptive or ophthalmic conditions. | 03-29-2012 |
20120095005 | Fused Bicyclic Pyrazole Derivatives As Kinase Inhibitors - A series of substituted pyrazolo[1,5-α][1,3,5]triazine and pyrazolo[1,5-αj-pyrimidine derivatives, being selective inhibitors of PI3 kinase enzymes, are accordingly of benefit in medicine, for example in the treatment of inflammatory, autoimmune, cardiovascular, neurodegenerative, metabolic, oncological, nociceptive or ophthalmic conditions. Formula (I). | 04-19-2012 |
Mizio Matteucci, Saffron Walden Essex GB
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20130012517 | Quinoline and Quinoxaline Derivatives as Kinase Inhibitors - A series of quinoline and quinoxaline derivatives, substituted by an optionally substituted bicyclic heteroaryl moiety consisting of two fused six-membered aromatic rings attached via an alkylene chain optionally linked to a heteroatom, being selective inhibitors of PI3 kinase enzymes, are accordingly of benefit in medicine, for example in the treatment of inflammatory, autoimmune, cardiovascular, neurodegenerative, metabolic, oncological, nociceptive or ophthalmic conditions. | 01-10-2013 |
20130018057 | Quinoline and Quinoxaline Derivatives as Kinase InhibitorsAANM Burli; RolandAACI Saffron Walden EssexAACO GBAAGP Burli; Roland Saffron Walden Essex GBAANM Haughan; Alan FindlayAACI Saffron Walden EssexAACO GBAAGP Haughan; Alan Findlay Saffron Walden Essex GBAANM Matteucci; M zioAACI Saffron Walden EssexAACO GBAAGP Matteucci; M zio Saffron Walden Essex GBAANM Owens; Andrew PateAACI Saffron Walden EssexAACO GBAAGP Owens; Andrew Pate Saffron Walden Essex GBAANM Raphy; GillesAACI Saffron Walden EssexAACO GBAAGP Raphy; Gilles Saffron Walden Essex GBAANM Sharpe; AndrewAACI Saffron Walden EssexAACO GBAAGP Sharpe; Andrew Saffron Walden Essex GB - A series of quinoline and quinoxaline derivatives, substituted by a fused bicyclic pyridine or pyrimidine moiety attached via an alkylene chain optionally linked to a heteroatom, being selective inhibitors of P13 kinase enzymes, are accordingly of benefit in medicine, for example in the treatment of inflammatory, autoimmune, cardiovascular, neurodegenerative, metabolic, oncological, nociceptive or ophthalmic conditions. | 01-17-2013 |
Mizio Matteucci, Saffron Walden GB
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20130079321 | PYRAZOL-4-YL-HETEROCYCLYL-CARBOXAMIDE COMPOUNDS AND METHODS OF USE - Pyrazol-4-yl-heterocyclyl-carboxamide compounds of Formula I, including stereoisomers, geometric isomers, tautomers, and pharmaceutically acceptable salts thereof, wherein X is thiazolyl, pyrazinyl, pyridinyl, or pyrimidinyl, are useful for inhibiting Pim kinase, and for treating disorders such as cancer mediated by Pim kinase. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed. | 03-28-2013 |
20140080801 | PYRAZOL-4-YL-HETEROCYCLYL-CARBOXAMIDE COMPOUNDS AND METHODS OF USE - Pyrazol-4-yl-heterocyclyl-carboxamide compounds of Formula I, including stereoisomers, geometric isomers, tautomers, and pharmaceutically acceptable salts thereof, wherein X is thiazolyl, pyrazinyl, pyridinyl, or pyrimidinyl, are useful for inhibiting Pim kinase, and for treating disorders such as cancer mediated by Pim kinase. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed. | 03-20-2014 |
Paul Brendon Matteucci, Coogee AU
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20160082250 | MULTI-SOURCE STIMULATION - A system and method are described for stimulating excitable tissue. The system includes a monopolar stimulation source that generates a sub-threshold field in the vicinity of the excitable tissue, the sub-threshold field being below a threshold at which activation of the excitable tissue occurs. One or more local stimulation sources generate a local field, which in combination with the sub-threshold field exceeds the threshold of the excitable tissue. | 03-24-2016 |