Patent application number | Description | Published |
20080242653 | Cyclopropyl amine derivatives - Compounds of formula (I) | 10-02-2008 |
20090054420 | BICYCLIC-SUBSTITUTED AMINES AS HISTAMINE-3 RECEPTOR LIGANDS - Compounds of formula (I) | 02-26-2009 |
20090105267 | OCTAHYDRO-PYRROLO[3,4-B]PYRROLE N-OXIDES - The invention relates to octahydro-pyrrolo[3,4-b]pyrrole N-oxides as prodrugs of CNS-active compounds, compositions comprising such compounds, methods for making the compounds, salts, and polymorphs, and methods of treating conditions and disorders using such compounds and compositions. Octahydro-pyrrolo[3,4-b]pyrrole N-oxides of formula (I) are prodrugs of histamine-3 antagonists, and are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Octahydro-pyrrolo[3,4-b]pyrrole N-oxide compounds, methods for using such compounds, compositions for making them, and processes for preparing such compounds are disclosed herein. | 04-23-2009 |
20090163464 | BENZOTHIAZOLE AND BENZOOXAZOLE DERIVATIVES AND METHODS OF USE - Compounds of formula (I) are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Also disclosed are pharmaceutical compositions of compounds of formula (I), methods for using such compounds and compositions, and a process for preparing the compounds. | 06-25-2009 |
20090221648 | COMPOSITIONS FOR TREATMENT OF COGNITIVE DISORDERS - The present invention relates to compositions for treatment of cognitive deficits. Such compositions can have a nicotinic acetylcholine receptor ligand, of either α4β2 subtype or α7 nicotinic acetylcholine subtype, and a histamine-3 receptor ligand, a method of using the same, and a related article of manufacture. Combinations of such active agents with psychostimulants or monoamine reuptake inhibitors also is contemplated. | 09-03-2009 |
20090253678 | MACROCYCLIC PYRIMIDINE DERIVATIVES - Macrocyclic pyrimidine compounds, compositions comprising such compounds, methods for making the compounds, and methods of treating and preventing the progression of diseases, conditions, and disorders using such compounds and compositions are described herein. | 10-08-2009 |
20090270364 | SUBSTITUTED PYRIMIDINE DERIVATIVES - The present application describes substituted pyrimidine compounds of formula (I) | 10-29-2009 |
20090326222 | BENZOTHIAZOLE CYCLOBUTYL AMINE DERIVATIVES - Compounds of formula (I) | 12-31-2009 |
20100004256 | HETEROARYL-FUSED MACROCYCLIC PYRIMIDINE DERIVATIVES - Heteroaryl-fused macrocyclic 2,4-diaminopyrimidine compounds of formula (I) | 01-07-2010 |
20100016344 | AMINO HETEROCYCLIC LINKED PYRIMIDINE DERIVATIVES - Macrocyclic benzofused pyrimidine compounds, compositions comprising such compounds, methods for making the compounds, and methods of treating and preventing the progression of diseases, conditions and disorders using such compounds and compositions are described herein. | 01-21-2010 |
20100273778 | TREATMENT OF OSTEOARTHRITIS PAIN - This invention discloses a method of treatment of osteoarthritis pain by administration of a histamine H | 10-28-2010 |
20100298291 | FUSED BICYCLIC-SUBSTITUTED AMINES AS HISTAMINE-3 RECEPTOR LIGANDS - Compounds of formula (I) | 11-25-2010 |
20100331294 | 4-SUBSTITUTED-2-AMINO-PYRIMIDINE DERIVATIVES - Compounds of the formula | 12-30-2010 |
20110098285 | BICYCLIC-SUBSTITUTED AMINES AS HISTAMINE-3 RECEPTOR LIGANDS - Compounds of formula (I) | 04-28-2011 |
20120108637 | Fused Bicyclic-Substituted Amines as Histamine-3 Receptor Ligands - Compounds of formula (I) | 05-03-2012 |
20120164070 | BENZOTHIAZOLE AND BENZOOXAZOLE DERIVATIVES AND METHODS OF USE - Compounds of formula (I) | 06-28-2012 |
20130040940 | MERCAPTOAMIDINE DERIVATIVES AND METHODS OF USE - Compounds of formula (I) | 02-14-2013 |