Manthey
Arne Manthey, Lachnersts DE
Patent application number | Description | Published |
---|---|---|
20110066275 | PRODUCTION MANAGEMENT SYSTEM - A monitoring system includes a control circuit configured to determine scrap values, yield values, and remainder values for at least a first operation and a second operation. The control circuit is configured to transmit one or more display signals. The one or more display signals include instructions to display a first operation status bar and a second operation status bar. The first operation status bar includes a first operation yield value, a first operation scrap value, and a first operation remainder value. The second operation status bar includes a second operation yield value, a second operation scrap value, and a second operation remainder value. | 03-17-2011 |
Arne Manthey, Mannheim DE
Patent application number | Description | Published |
---|---|---|
20140278737 | PRESENTING CHARACTERISTICS OF CUSTOMER ACCOUNTS - In general, the subject matter described in this disclosure can be embodied in methods, systems, and program products. Multiple customer accounts for which to display a graph that illustrates differences between characteristics of the multiple customer accounts are identified. A display of the graph that illustrates the differences between the characteristics of the multiple customer accounts is presented. User input that interacts with the displayed graph to select the user interface elements for a subset of the multiple customers is received. The selected user interface elements are presented in a different manner than the indication for those of the multiple customers that have not been selected. | 09-18-2014 |
Carl Manthey, Chester Springs, PA US
Patent application number | Description | Published |
---|---|---|
20120302573 | METHODS OF INHIBITING PRO MATRIX METALLOPROTEINASE ACTIVATION - This invention relates to methods for preventing, treating or ameliorating an MMP9 and/or MMP13 mediated syndrome, disorder or disease comprising administering to a subject in need thereof an effective amount of a compound listed in the examples section of this specification, or a form, composition or medicament thereof. Disorders treated and/or prevented include rheumatoid arthritis. | 11-29-2012 |
20130040994 | Methods of Treatment Using Allosteric Processing Inhibitors for Matrix Metalloproteinases - The present invention includes a crystal comprising a complex of the pro form of a matrix metalloprotease (proMMP) and a small-molecule allosteric processing inhibitor that inhibits that activation of the proMMP, methods for identifying small-molecule allosteric processing inhibitors that inhibit the activation of a proMMP, and methods of treatment using small-molecule allosteric processing inhibitors that inhibit the activation of a proMMP. The present invention relates to the crystal structure of a complex of proMMP9 bound to a small-molecule allosteric processing inhibitor that inhibits activation of proMMP9. The invention further relates to the use of the methods and the crystal and related structural information for designing, selecting and/or optimizing small-molecule allosteric processing inhibitors that inhibit activation of proMMP9 and proMMP9 homologues. The present invention also relates to the use of small-molecule allosteric processing inhibitors for the treatment of diseases mediated by inappropriate matrix metalloproteinase (MMP) activity. | 02-14-2013 |
Carl L. Manthey, Chester Springs, PA US
Patent application number | Description | Published |
---|---|---|
20160015700 | 4-CYANO-N-(2-(4,4-DIMETHYLCYCLOHEX-1-EN-1-YL)-6-(2,2,6,6-TETRAMETHYLTETRAH- YDRO-2H-PYRAN-4-YL)PYRIDIN-3-YL)-1H-IMIDAZOLE-2-CARBOXAMIDE FOR THE TREATMENT OF HODGKIN'S LYMPHOMA - The present invention is directed to methods for the treatment of Hodgkin's lymphoma comprising administering to a patient in need thereof, a therapeutically effective amount of 4-cyano-N-(2-(4,4-dimethylcyclohex-1-en-1-yl)-6 -(2,2,6,6-tetramethyltetrahydro-2H-pyran-4-yl)pyridin-3-yl)-1H-imidazole-2-carboxamide as mono-therapy or as combination or co-therapy with one or more chemotherapeutic agent or chemotherapy regimens. | 01-21-2016 |
Carl L. Manthey, Downingtown, PA US
Patent application number | Description | Published |
---|---|---|
20090148883 | BIOMARKER FOR ASSESSING RESPONSE TO FMS TREATMENT - A biomarker that correlates to treatment with drugs that inhibit FMS is disclosed. This biomarker has been shown to have utility in assessing response to the compounds. The plasma level of the biomarker is increased upon treatment with FMS inhibitor compounds, thus indicating that this biomarker is involved in FMS activity. | 06-11-2009 |
Carl M. Manthey, Chester Springs, PA US
Patent application number | Description | Published |
---|---|---|
20140005225 | METHOD OF INHIBITING C-KIT KINASE | 01-02-2014 |
20150094520 | METHOD OF INHIBITING C-KIT KINASE - A method of reducing or inhibiting kinase activity of C-KIT in a cell or a subject, and the use of such compounds for preventing or treating in a subject a cell proliferative disorder and/or disorders related to C-KIT using a compound of the present invention: | 04-02-2015 |
Christian Manthey, Duisburg DE
Patent application number | Description | Published |
---|---|---|
20110036599 | EXTINGUISHING FIRES AND SUPPRESSING EXPLOSIONS - A fire extinguishing or explosion suppression device comprises a chamber and a nozzle. The nozzle defines a discharge pathway from the chamber. The chamber has an inlet for pressure-driven introduction of a liquid into the chamber. The chamber is shaped so that a gas contained in the chamber before the introduction of the liquid is entrained into the liquid during the pressure driven introduction of the liquid such that a mixture of the liquid and the gas is discharged through the nozzle to create a mist for extinguishing a fire or suppression of an explosion. After the gas has been discharged from the chamber, the nozzle produces a spray having a core of larger liquid droplets with the core being surrounded by smaller liquid droplets. | 02-17-2011 |
David M. Manthey, Kent, WA US
Patent application number | Description | Published |
---|---|---|
20090008388 | MULTI-USE CARRIER - A single unit cardboard carrier is transformed from a collapsed state into an expanded multi-use carrier with a minimum of assembly actions. A preferred embodiment of the multi-use carrier has a central chamber, a plurality of vessel apertures located around the centered chamber, and has a handle spanning across the chamber. | 01-08-2009 |
20110139639 | MULTI-USE CARRIER - A single unit cardboard carrier is transformed from a collapsed state into an expanded multi-use carrier with a minimum of assembly actions. A preferred embodiment of the multi-use carrier has a central chamber, a plurality of vessel apertures located around the centered chamber, and has a handle spanning across the chamber. | 06-16-2011 |
Jeffrey A. Manthey, Iowa City, IA US
Patent application number | Description | Published |
---|---|---|
20100075383 | METHODS FOR AMPLIFYING POLYMERIC NUCLEIC ACIDS - The invention provides compositions and methods for amplifying nucleic acid polymer sequences in a high complexity nucleic acid sample. The unique compositions of the invention include a primer set composed of a mixture of two types of primers for DNA synthesis. For extension in one direction, the primers all contain modifications that destroy their ability to serve as templates that can be copied by DNA polymerases. For extension in the opposite direction the set includes at least one primer that can serve as a template and be replicated by DNA polymerases throughout its length. The method can be carried out by mixing the nucleic acid polymer sequence of interest with the set of DNA synthesis primers in an amplification reaction mixture. The reaction mixture is then subjected to temperature cycling analogous to the temperature cycling in PCR reactions. At least one primer in the primer set hybridizes to the nucleic acid polymer. It is preferred that the non-replicable primer hybridizes to the nucleic acid polymer and is extended to produce an extension product that contains sequence from the nucleic acid polymer to which the replicable primer then hybridizes. Of course, if the nucleic acid polymer is double stranded, both the replicable and nonreplicable primers will hybridize and be extended by DNA polymerase. | 03-25-2010 |
Jeffrey A. Manthey, North Liberty, IA US
Patent application number | Description | Published |
---|---|---|
20110117559 | SMALL RNA DETECTION ASSAYS - The present invention comprises use of cleavable primers to perform qPCR detection of cDNA made from small RNA species. The cleavable primers offer improved specificity over standard PCR primers and are the method is compatible with a variety of methods to introduce priming sites at the 5′-end and 3′-end of the small RNA species. | 05-19-2011 |
John A. Manthey, Stanwood, WA US
Patent application number | Description | Published |
---|---|---|
20110167009 | CONTROLLED-VENDOR MANUFACTURING METHODS - Embodiments of the invention are directed to manufacturing a medical device in a way that minimizes the possibility of defects. Because of the general increasing desire to eliminate lead from the environment, electronic producers are removing lead from their manufacturing processes. The lead had beneficial qualities, however, in that it prevented other metals, in particular tin, from developing “whiskers,” believed to be caused from thermal and mechanical stress of the tin parts or components. Removing the lead has caused an increasing incidence of failure in electronic devices. Many vendors, believing that lead-free devices are universally desirable, routinely substitute lead-free components for components that previously contained lead. Oftentimes these substitutions are made without knowledge of the buyer. Some devices, in particular life-saving devices, may be adversely affected by such a substitution. Embodiments of the invention prevent non-specified goods from being assembled into the medical device by generating evidence or requiring that vendors generate evidence of component composition for particular components that may be at risk for premature failure in the medical device. | 07-07-2011 |
Katja Manthey, Berlin DE
Patent application number | Description | Published |
---|---|---|
20120152704 | Casing Of A Circuit Breaker, In Particular Of A Circuit Breaker For Nominal Currents Above 250A - A casing of a circuit breaker for nominal currents above 250A that enables at least one rigid busbar to be swung in to make contact with at least one switching pole attached in the casing. The casing may include a bottom section that cuboidally includes a rectangular base area and two rectangular side faces connected to the base area and running parallel to one another. Adjacent side faces are connected to one another via at least two stays which are arranged away from the opposing openings, delimited by the side faces, of the cuboidal bottom section, so that a switching pole can be inserted between the stays into the bottom section and so that a rigid busbar can be swung in at one of the two openings in order to make contact with the switching pole, when busbar and bottom section are each premounted, for example in a switching cabinet. | 06-21-2012 |
20120186957 | Electric Switch - An electric switch is disclosed including an at least two-part housing including a first housing part, a second housing part connected to the first housing part and including at least one pole cartridge which is enclosed by the two-part housing and is preassembled in the second housing part. In at least one embodiment, the first housing part is connected to the pole cartridge with the aid of at least one fastening device. | 07-26-2012 |
20130056338 | METHOD FOR LOCKING A COVER OF AN ELECTRICAL SWITCH - A device is disclosed including a removable cover of a housing of an electrical switch and a handle. In at least one embodiment, the handle, by way of its position, switches the electrical switch between different states. Further, the handle is connected to the housing and the handle includes a contour which is embodied, at least in one position of the handle, to interact with the cover for locking the removable cover. | 03-07-2013 |
Kevin W. Manthey, Alpharetta, GA US
Patent application number | Description | Published |
---|---|---|
20140122455 | Systems and Methods for Intelligent Parallel Searching - Systems and methods are provided for conducting intelligent parallel searches of data sources. A search engine receives a request to access target data that is stored in at least one of multiple data sources. Each data source has a candidate index. The search engine extracts inquiry parameters from the request. The inquiry parameters corresponds to sub-indices of respective general indices. Each general index includes an index of relationships between data from at least two of the data sources. Each sub-index includes a subset of the respective general index. The search engine performs parallel searches of the general indices common to the data sources. Each parallel search includes searching the sub-indices based on corresponding inquiry parameters for the sub-indices. The search engine performs additional parallel searches of the candidate indices based on results of the parallel searches. The search engine extracts an output from results of the additional parallel searches. | 05-01-2014 |
Pierre Manthey, Oberursel DE
Patent application number | Description | Published |
---|---|---|
20150233641 | MACHINE FOR THE THERMAL TREATMENT OF BULK MATERIAL - This invention relates to a machine for the thermal treatment of bulk material, in particular a sintering or pelletizing machine, comprising a travelling grate ( | 08-20-2015 |
Robert Manthey, Corinda AU
Patent application number | Description | Published |
---|---|---|
20090187382 | REMOTE PUMPING STATION MONITORING - The present invention relates to a monitoring method for monitoring a remote pumping station in communication with a computational device via the Internet. An embodiment of a method may comprise requesting, using the computational device, pumping station information from the pumping station. The pumping station information may then be received by the computational device. The pumping station information may be in the form of a pumping station profile. In one embodiment, information from the pumping station profile is displayed on a display of the computational device. The information displayed would typically comprise the water level, and indicators of the activation set points and deactivation set points for the pumps. | 07-23-2009 |