Patent application number | Description | Published |
20090281192 | Process for the Preparation of and Crystalline Forms of Optical Enantiomers of Modafinil - The invention relates to a polymorphic form of (−)-modafinil that produces a powder X-ray diffraction spectrum comprising intensity peaks corresponding to interplanar spacings of about 12.38, 8.58, 7.34, 5.00 and 4.09 Å, and a process for the preparation thereof. | 11-12-2009 |
20090281193 | Process for the Preparation of and Crystalline Forms of Optical Enantiomers of Modafinil - The invention relates to a polymorphic form of (−)-modafinil that produces a powder X-ray diffraction spectrum comprising intensity peaks corresponding to interplanar spacings of about 9.45, 7.15, 5.13, 4.15 and 3.67 Å, and a process for the preparation thereof. | 11-12-2009 |
20100022653 | Process for the Preparation of and Crystalline Forms of Optical Enantiomers of Modafinil - The invention relates to a polymorphic form of (−)-modafinil that produces a powder X-ray diffraction spectrum comprising intensity peaks corresponding to interplanar spacings of about 8.54, 4.56, and 3.78 Å, and a process for the preparation thereof. | 01-28-2010 |
20100048718 | Process for the Preparation of and Crystalline Forms of Optical Enantiomers of Modafinil - The invention relates to a polymorphic form of (−)-modafinil that produces a powder X-ray diffraction spectrum comprising intensity peaks corresponding to interplanar spacings of about 5.23, 5.03, 4.22 and 4.10 Å, and a process for the preparation thereof. | 02-25-2010 |
20100048719 | Process for the Preparation of and Crystalline Forms of Optical Enantiomers of Modafinil - The invention relates to a polymorphic form of (−)-modafinil that produces a powder X-ray diffraction spectrum comprising intensity peaks corresponding to interplanar spacings of about 12.31, 8.54, 7.27 and 3.62 Å, and a process for the preparation thereof. | 02-25-2010 |
20100048720 | Process for the Preparation of and Crystalline Forms of Optical Enantiomers of Modafinil - The invention relates to a polymorphic form of (−)-modafinil that produces a powder X-ray diffraction spectrum comprising intensity peaks corresponding to interplanar spacings of about 14.14, 10.66, 7.80 and 4.02 Å, and a process for the preparation thereof. | 02-25-2010 |
Patent application number | Description | Published |
20090148454 | Peptide Domain Required For Interaction Between The Envelope of a Virus Pertaining to The Herv-W Interference Group and an Hasct Receptor - The invention relates to a peptide domain required for interaction between the envelope of a virus pertaining to the HERV-W interference group and a hASCT receptor, comprising an N end point and a C end point. Said peptide domain is defined, at the N end point thereof, by a pattern formed by the amino acids L (Z)-proline-cysteine-X-cysteine in which Z is any amino acid, is a whole number between 2 and 30, and X is any amino acid, and at the C end point thereof, by a pattern formed by the amino acids serine-aspartic acid-Xa-Xb-Xc-Xd-Xe-aspartic acid-Xf-Xg-(Z) in which Xa, Xb, Xc, Xd, Xe, Xf, Xg are any amino acids, Z is any amino acid, B is a whole number between 15 and 25, preferably 20. The peptide domain comprises, between the N end point and the C end point, at least one pattern selected from the following patterns: a pattern formed by the amino acids cysteine-X2-X3-X4-X5-X6-cysteine in which X2, X3, X4, X5, X6 are any amino acids, and a pattern formed by the amino acids cysteine-X7-X8-X9-X10-X11-X12-X13-X14-X15-cysteine-trytophane in which X7, X8, X9, X10, X11, X12, X13, X14, X15 are any amino acids. | 06-11-2009 |
20100285448 | RETROVIRAL NUCLEIC MATERIAL AND NUCLEOTIDE FRAGMENTS, IN PARTICULAR ASSOCIATED WITH MULTIPLE SCLEROSIS AND/OR RHEUMATOID ARTHRITIS, FOR DIAGNOSTIC, PROPHYLACTIC AND THERAPEUTIC USES - An isolated polynucleotide having a nucleotide sequence selected from the group consisting of (a) SEQ ID NO: 21, (b) the full-length sequences encoding a polypeptide having a peptide sequence selected from the group consisting of SEQ ID NOs: 25 and 26, and (c) the full-length complementary sequences to the sequences set forth in (a) or (b). | 11-11-2010 |
20100330580 | METHOD FOR THE IN VITRO DIAGNOSIS OR PROGNOSIS OF TESTICULAR CANCER - A method for in vitro diagnosis or prognosis of testicular cancer in a biological sample from a patient suspected of suffering from testicular cancer, having a step of detecting the presence or absence of methylation of CpG dinucleotides in at least one genomic DNA target sequence of the sample, the target sequence being selected from at least one of the sequences identified in SEQ ID NOS: 1 to 7 or from at least one sequence which exhibits at least 99% identity with one of the sequences identified in SEQ ID NOS: 1 to 7 and the sequences complementary thereto; to the DNA sequences and to the use thereof as a testicular cancer marker. | 12-30-2010 |
20100330581 | METHOD FOR IN VITRO DIAGNOSIS OR PROGNOSIS OF TESTICULAR CANCER - The invention relates to a method for in vitro diagnosis or prognosis of testicular cancer which comprises a step of detecting the presence or absence of at least one expression product from at least one nucleic acid sequence selected from the sequences identified in SEQ ID NOS: 1 to 6 or from the sequences which exhibit at least 99% identity with one of the sequences identified in SEQ ID NOS: 1 to 6, to isolated nucleic acid sequences and to the use thereof as a testicular cancer marker. | 12-30-2010 |
20120190569 | ENDOGENETIC RETROVIRAL SEQUENCES, ASSOCIATED WITH AUTOIMMUNE DISEASES OR WITH PREGNANCY DISORDERS - A genomic retroviral nucleic material, in an isolated or purified state, at least partially functional or non-functional, wherein the genome comprises a reference nucleotide sequence selected from the group including sequences of SEQ ID NOs: 1-15, their complementary sequences, and their equivalent sequences, in particular, nucleotide sequences having, for every series of 100 contiguous monomers, at least 70% and preferably at least 90% homology with the sequences of SEQ ID NOs: 1-15. | 07-26-2012 |
20130115602 | ENDOGENETIC RETROVIRAL SEQUENCES, ASSOCIATED WITH AUTOIMMUNE DISEASES OR WITH PREGNANCY DISORDERS - A genomic retroviral nucleic material, in an isolated or purified state, at least partially functional or non-functional, wherein the genome comprises a reference nucleotide sequence selected from the group including sequences of SEQ ID NOs: 1-15, their complementary sequences, and their equivalent sequences, in particular, nucleotide sequences having, for every series of 100 contiguous monomers, at least 70% and preferably at least 90% homology with the sequences of SEQ ID NOs: 1-15. | 05-09-2013 |
20130172209 | METHOD FOR IN VITRO DIAGNOSIS OR PROGNOSIS OF TESTICULAR CANCER - The invention relates to a method for in vitro diagnosis or prognosis of testicular cancer which comprises a step of detecting the presence or absence of at least one expression product from at least one nucleic acid sequence selected from the sequences identified in SEQ ID NOS: 1 to 6 or from the sequences which exhibit at least 99% identity with one of the sequences identified in SEQ ID NOS: 1 to 6, to isolated nucleic acid sequences and to the use thereof as a testicular cancer marker. | 07-04-2013 |
20140349857 | METHOD FOR IN VITRO DIAGNOSIS OR PROGNOSIS OF COLON CANCER - The present invention relates to a method for in vitro diagnosis or prognosis of colon cancer, including a step of detecting at least one expression product of at least one HERV nucleic acid sequence, the use of said isolated nucleic acid sequences as a molecular marker/molecular markers, and a kit including at least one specific binding partner for at least one expression product of the HERV nucleic acid sequences. | 11-27-2014 |
20140349875 | METHOD FOR THE IN VITRO DIAGNOSIS OR PROGNOSIS OF TESTICULAR CANCER - A method for in vitro diagnosis of testicular cancer includes (i) obtaining a biological sample from a patient suspected of having testicular cancer, (ii) performing an assay to determine the methylation status of CpG dinucleotides in a genomic DNA target sequence, the DNA target sequence being the 5′ LTR U3 promoter sequence of the ERVWE1 locus, optionally further including an activator sequence directly upstream of the 5′ LTR U3 promoter sequence, and (iii) diagnosing the patient with testicular cancer when the DNA target sequence is hypomethylated as compared to a methylation status indicative of the absence of testicular cancer. | 11-27-2014 |
20140370503 | METHOD FOR THE DIAGNOSIS OR PROGNOSIS, IN VITRO, OF PROSTATE CANCER - The present invention relates to a method for the in vitro diagnosis or prognosis of prostate cancer, which includes a step of detecting at least one expression product of at least one HERV nucleic acid sequence, the use of said nucleic acid sequences, once isolated, as one or more molecular marker(s) and a kit comprising at least one specific binding partner of at least one of the expression products of the HERV nucleic acid sequences. | 12-18-2014 |
20150018222 | METHOD FOR IN VITRO DIAGNOSIS OR PROGNOSIS OF BREAST CANCER - The present invention relates to a method for the in vitro diagnosis or prognosis of breast cancer, which includes a step of detecting at least one expression product of at least one HERV nucleic acid sequence, the use of said nucleic acid sequences, once isolated, as one or more molecular marker(s) and a kit including at least one specific binding partner of at least one of the expression products of the HERV nucleic acid sequences. | 01-15-2015 |
20150065368 | METHOD FOR THE IN VITRO DIAGNOSIS OR PROGNOSIS OF OVARIAN CANCER - The present invention relates to a method for the in vitro diagnosis or prognosis of ovarian cancer, which includes a step of detecting at least one expression product of at least one HERV nucleic acid sequence, the use of said nucleic acid sequences, once isolated, as one or more molecular marker(s) and a kit including at least one specific binding partner of at least one of the expression products of the HERV nucleic acid sequences. | 03-05-2015 |
20150065369 | METHOD FOR THE DIAGNOSIS OR PROGNOSIS, IN VITRO, OF TESTICULAR CANCER - The subject matter of the present invention is a method for the diagnosis or prognosis, in vitro, of testicular cancer, which includes a step of detecting at least one expression product of at least one HERV nucleic acid sequence, the use of said nucleic acid sequences, which have been isolated, as a molecular marker or molecular markers, and a kit including at least one binding partner specific for at least one of the expression products of the HERV nucleic acid sequences. | 03-05-2015 |
Patent application number | Description | Published |
20080312171 | Tetracycline-Dependent Regulation of Rna Interference - The present invention relates to a tetracycline dependent gene regulatory system or composition controlling the expression of a target gene in a cell and to methods using said system or composition. The present invention more specifically discloses compositions, vectors and methods allowing tetracycline-controlled expression of short-hairpin RNAs (shRNAs), and demonstrates inducible, reversible and stable RNA interference (RNAi) using the same in a cell. The invention can be used to cause reversible control of the expression of any gene and may therefore find applications in the fields of mammalian, in particular human, genetics and molecular therapeutics, in cell and gene therapy, research as well as in genetic studies using transgenic animals. | 12-18-2008 |
20100098664 | Lentiviral vectors allowing RNAi mediated inhibition of GFAP and vimentin expression - The present invention relates to method for preventing, treating or alleviating a central nervous system (CNS) disorder using a non replicative lentivirus comprising a lentiviral genome comprising a nucleic acid sequence producing at least one functional miRNA, at least one functional shRNA and/or at least one functional siRNA, preferably derived from said shRNA, said miRNA, shRNA or siRNA being designed to silence the expression of a gene that encodes a protein of the astrocyte cytoskeleton. The present invention further relates to compositions and kits comprising such a lentivirus as well as to uses thereof. | 04-22-2010 |
20100100978 | RNAi MEDIATED EXPRESSION INHIBITION OF A CHOLINERGIC PROTEIN - The present invention relates to nucleic acid sequences producing at least one functional miRNA, at least one functional shRNA and/or at least one functional siRNA, said miRNA, shRNA or siRNA being designed to silence the expression of a gene that encodes a cholinergic protein. The present invention further relates to compositions and kits comprising such nucleic acid sequences as well as to uses thereof. | 04-22-2010 |
20130210739 | BHLH PROTEINS AND THEIR USE AS DRUGS - The present invention relates to at least one protein belonging to the bHLH family and/or at least a nucleic acid molecule coding for the bHLH proteins as drug. | 08-15-2013 |
Patent application number | Description | Published |
20090327420 | CONTROLLED SHARING OF PERSONAL DATA - A first user of a first communicating object shares personal data in response to a request from a second user. The shared data are associated with a reference of the second user in the first communicating object and are transmitted to the second communicating object in order to be recorded therein in association with a reference of the first user. The first user controls the shared personal data from the first communicating object by transmitting a control instruction to the second communicating object. The instruction contains at least the reference of the first user in order to find the personal data of the first user in association with the reference in the second communicating object, and to treat the personal data according to the transmitted control instruction. | 12-31-2009 |
20100287248 | METHOD AND OBJECT FOR EXTRACTING CONTENT HAVING A COMMERCIAL ASPECT FROM A MESSAGE EMITTED IN A RADIOCOMMUNICATION NETWORK - In order to broadcast a commercial content corresponding to the centres of interest of a user of a communicating object, the disclosed method involves generating a message including at least one piece of commercial content associated with at least one piece of meta-information characterising the subject concerned by the commercial content. The method is implemented by the object for extracting a piece of commercial content from the message only if the piece of meta-information of the content corresponds to a piece of meta-information characterising a centre of interest of the user. | 11-11-2010 |
20110119695 | METHOD OF DETECTING TV OFF EVENT ON A MOBILE TERMINAL EQUIPMENT - The invention is a method of detecting a TV off event happening on a mobile terminal equipment which is assumed to receive a broadcast service. A portable electronic device is connected to the mobile terminal equipment and, the mobile terminal equipment sends periodic commands to the portable electronic device. The mobile terminal equipment sends control messages to the portable electronic device. The control messages are related to the broadcast service. The method includes the steps of identifying a duration either according to receipt of two periodic commands of a first type or according to data contained in control messages, and identifying the TV off event if no control message has been received during that duration. | 05-19-2011 |
20120173482 | METHOD FOR ENRICHMENT AN ELECTRONIC PHONE BOOK PROVOKED BY A CHANGE IN THE ASSOCIATED TERMINAL, AND ASSOCIATED DEVICE - The invention relates to a method for the enrichment of an electronic directory stored in a first electronic communication device, based on the changes in a second electronic communication device and by the application of decisional rules. The changes can also be related to a change in the hardware or software functionalities or to a modification of data contained in said second device. | 07-05-2012 |
20140080444 | METHOD FOR UPDATING SECURE ELEMENTS INCLUDED IN TERMINALS OF A TELECOMMUNICATION NETWORK AND CORRESPONDING UPDATE SERVER - The invention relates, in particular, to a method for updating secure elements included in terminals of a telecommunication network. The terminals connect, for recurring updates and according to a first order, to a server of the network such that said server can transmit data thereto. In the context of a process for updating the secure elements, the method comprises transmitting messages requesting connection to the secure elements such that the latter connect to the server. According to the invention, the method comprises the prioritized transmission of the messages requesting connection to the secure elements in an order that is the reverse of the first order, in order to update, on a prioritized basis, the last secure elements that were updated by the recurrent updates from the start of the update process. | 03-20-2014 |
Patent application number | Description | Published |
20100138124 | HILL START ASSISTANCE METHOD AND ASSOCIATED DEVICE - A hill start assistance method for a vehicle held in a stationary position by a braking system supplying a braking pressure, the braking system connected to a master cylinder controlled by a pressure transmitted by a user via a brake pedal. The method includes, upon detection of the release of pressure from the brake pedal by a pressure sensor: triggering a time-out; calculating a minimum pressure for holding the vehicle in a stationary position; and adjusting the braking pressure using the braking system such as to reduce the braking pressure in the braking system progressively. The system acts as a pressure regulator, and at the end of the time-out at the latest, the braking pressure is equal to a target pressure that is at least equal to the minimum pressure for holding the vehicle stationary. | 06-03-2010 |
20100138129 | HILL START ASSISTANCE METHOD FOR MOTOR VEHICLES - A hill start assistance method for a user of a vehicle having a braking system and an electronic braking control, provided with at least one master cylinder pressure sensor, whereby the pressure on each caliper of the vehicle can be controlled. The method includes: estimating the torque transmitted by the clutch, recording information corresponding to the value of the master cylinder pressure resulting from a user's actuation of the brake pedal, and recording the information recorded corresponding to the value of the master cylinder pressure when the user actuates the brake pedal again by pressing harder on the pedal or partially releasing same. When the user releases the brake pedal fully, the braking system maintains the pressure on the calipers for a predetermined period of time, as a function of a pressure set value equal to the value of the last item of information recorded. | 06-03-2010 |
20100235064 | ASSISTANCE DEVICE FOR UPHILL MOVEMENTS OF AN AUTOMOBILE - An assistance device for uphill movements of an automobile, including a first assistance calculator controlling a parking brake and automatically controlling release thereof when it is activated and when driving torque transmitted by a clutch is higher than a minimum threshold for maintaining the vehicle on a slope, a second assistance calculator controlling the driving brake and automatically controlling and maintaining its activation when it has been activated, when it is determined that the vehicle is immobile and when the clutch torque is lower than the minimum threshold, and automatically controlling the release thereof when it is activated and when the clutch torque is higher than the threshold, and a mechanism determining immobility of the vehicle, estimating the clutch torque, estimating the slope, and calculating a threshold. | 09-16-2010 |
20100241328 | METHOD FOR HILL START ASSISTANCE FOR MOTOR VEHICLE - A method for hill start assistance for a motor vehicle and to an associated device that includes a clutch and a transmission between the clutch and driving wheels of the vehicle. The method determines the torque of the clutch for maintaining the vehicle in an immobile position based on a known engine torque, wherein the torque of the clutch is determined by taking into account a portion of the engine torque dedicated to operation of constituent mechanisms of the vehicle other than the clutch. | 09-23-2010 |
20110202245 | METHOD FOR ASSISTING WITH HILL STARTS - A method for assisting a motor vehicle with a hill start, the motor vehicle having previously been held stationary when parked by a brake. The method measures inclination of the vehicle, previously establishes a map between engine torque and engine speed, defines, within the map, an authorized zone and a forbidden zone, provides a vehicle engine speed value, provides a vehicle engine torque value, deduces from these coordinates of the engine operating point within the map, and releases the brake automatically only if the coordinates of the operating point lie within the authorized zone of the map. | 08-18-2011 |
20120179351 | METHOD FOR CONTROLLING AN ADAPTIVE CRUISE CONTROL SYSTEM AND ASSOCIATED CONTROL SYSTEM - A control of a motor vehicle adaptive cruise control system in which a computer of the control system receives a set point speed value and information relating to the speed unit from an instrument panel computer via a CAN bus. The information relating to the speed unit received at the moment of activation of the cruise control system is stored in memory, and throughout the time for which the cruise control system is activated, any change in the information relating to the speed unit received by comparison with the information stored in memory is monitored. If need be, an information item relating to a speed unit fault is generated. | 07-12-2012 |