Maciag
Anna E. Maciag, Frederick, MD US
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20120238518 | DIAZENIUMDIOLATED COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHOD OF TREATING CANCER - Disclosed is a method of treating cancer in a patient comprising administering to the patient an effective amount of a diazeniumdiolated (N | 09-20-2012 |
20140315865 | HYBRID DIAZENIUMDIOLATED COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHOD OF TREATING CANCER - Disclosed are hybrid compounds that release both nitric oxide and a moiety that inhibits poly (ADP-ribose) polymerase (PARP), e.g., a compound or a pharmaceutically acceptable salt thereof of formula (I), wherein R | 10-23-2014 |
Carla Maciag, Wilmington, DE US
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20100168130 | Diarylmethyl Piperazine Derivatives, Preparations Thereof and Uses Thereof - Compounds of general formula: | 07-01-2010 |
20120149717 | Diarylmethyl Piperazine Derivatives, Preparations Thereof and Uses Thereof - Compounds of general formula: | 06-14-2012 |
Dan Maciag, Essexville, MI US
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20120318810 | CONTAINER HAVING ENHANCED WALL INTEGRITY AND ALIGNMENT ELEMENT - A container having enhanced wall integrity and a rotational element is provided that includes a sidewall having polygonal cross-sectional shape and an alignment structure formed therein. The alignment structure is adapted for orienting the container with respect to a second container such that the panel sections of the containers become parallel with one another and the containers may be fully nested one within the other. The alignment structure can be recessed into the sidewall to form peaks and valleys along an inner surface of the container. The peaks include first and second faces sloping in opposite directions designed to direct corners of the first container's sidewall toward the interior valleys of the second container in order to orient the containers as they are stacked. | 12-20-2012 |
Kathleen Ann Murphy Maciag, Cincinnati, OH US
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20120330262 | Absorbent Article With Waistband Having Contraction - A disposable absorbent article comprising a first waist region, a second waist region, a crotch region disposed between the first waist region and second waist region; a first waist edge and a second waist edge; the disposable absorbent article comprising a first waistband near the first waist edge and a second waistband near the second waist edge, wherein the Front-to-Back Delta Chassis Contraction is greater than about 9.0%. | 12-27-2012 |
Lorraine A. Maciag, South Freeport, ME US
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20090123565 | Copper-dependent non-traditional pro-inflammatory cytokine export and methods, compositions and kits relating thereto - The present invention relates to the discovery that non-traditional export of certain pro-inflammatory cytokines lacking a signal sequence from a cell can be inhibited by copper chelation and/or administration to the cell of a truncated form of S100A13 lacking the basic residue portion. Further, copper chelation inhibits, inter alia, neointima formation, macrophage infiltration and associated inflammation, cell proliferation, secretion of extracellular matrix, intimal thickening, adventitial angiogenesis, restenosis, and the like, associated with vascular vessel injury. Thus, the present invention provides novel methods of preventing and treating, and for identifying novel compounds also useful as therapeutics for, such conditions. | 05-14-2009 |
Paulo Maciag, Princeton, NJ US
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20090186051 | Compositions comprising HMW-MAA and fragments thereof, and methods of use thereof - This invention provides recombinant polypeptides comprising a fragment of a High Molecular Weight Melanoma-Associated Antigen (HMW-MAA), recombinant | 07-23-2009 |
20090202587 | COMPOSITIONS COMPRISING HMW-MAA AND FRAGMENTS THEREOF, AND METHODS OF USE THEREOF - This invention provides recombinant polypeptides comprising a fragment of a High Molecular Weight Melanoma-Associated Antigen (HMW-MAA), recombinant | 08-13-2009 |
Paulo Maciag, Robbinsville, NJ US
Patent application number | Description | Published |
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20110129499 | DUAL DELIVERY SYSTEM FOR HETEROLOGOUS ANTIGENS - Provided herein are recombinant | 06-02-2011 |
20120114685 | COMPOSITIONS COMPRISING ANGIOGENIC FACTORS AND METHODS OF USE THEREOF - The present invention provides recombinant | 05-10-2012 |
20140248304 | NON-HEMOLYTIC LLO FUSION PROTEINS AND METHODS OF UTILIZING SAME - The present invention provides recombinant proteins or peptides comprising a mutated listeriolysin O (LLO) protein or fragment thereof, comprising a substitution or internal deletion of the cholesterol-binding domain or a portion thereof, fusion proteins or peptides comprising same, nucleotide molecules encoding same, and vaccine vectors comprising or encoding same. The present invention also provides methods of utilizing recombinant proteins, peptides, nucleotide molecules, and vaccine vectors of the present invention to induce an immune response to a peptide of interest. | 09-04-2014 |
Paulo Maciag, Long Grove, IL US
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20140335120 | DUAL DELIVERY SYSTEM FOR HETEROLOGOUS ANTIGENS - Provided herein are recombinant | 11-13-2014 |
Paulo Maciag, Northbrook, IL US
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20140314708 | DUAL DELIVERY SYSTEM FOR HETEROLOGOUS ANTIGENS - Provided herein are recombinant | 10-23-2014 |
20150079034 | COMPOSITIONS COMPRISING ANGIOGENIC FACTORS AND METHODS OF USE THEREOF - The present invention provides recombinant | 03-19-2015 |
Paulo C. Maciag, Long Grove, IL US
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20150238584 | COMPOSITIONS AND METHODS FOR PREVENTION OF ESCAPE MUTATION IN THE TREATMENT OF HER2/NEU OVER-EXPRESSING TUMORS - This invention provides compositions and methods for treating and vaccinating against a Her2/neu antigen-expressing tumor and inducing an immune response against dominant in a non-human animal. | 08-27-2015 |
Paulo Cesar Maciag, Princeton, NJ US
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20090081248 | Non-hemolytic LLO fusion proteins and methods of utilizing same - The present invention provides recombinant proteins or peptides comprising a mutated listeriolysin O (LLO) protein or fragment thereof, comprising a substitution or internal deletion of the cholesterol-binding domain or a portion thereof, fusion proteins or peptides comprising same, nucleotide molecules encoding same, and vaccine vectors comprising or encoding same. The present invention also provides methods of utilizing recombinant proteins, peptides, nucleotide molecules, and vaccine vectors of the present invention to induce an immune response to a peptide of interest. | 03-26-2009 |
Thomas Maciag, Portland, ME US
Patent application number | Description | Published |
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20090123565 | Copper-dependent non-traditional pro-inflammatory cytokine export and methods, compositions and kits relating thereto - The present invention relates to the discovery that non-traditional export of certain pro-inflammatory cytokines lacking a signal sequence from a cell can be inhibited by copper chelation and/or administration to the cell of a truncated form of S100A13 lacking the basic residue portion. Further, copper chelation inhibits, inter alia, neointima formation, macrophage infiltration and associated inflammation, cell proliferation, secretion of extracellular matrix, intimal thickening, adventitial angiogenesis, restenosis, and the like, associated with vascular vessel injury. Thus, the present invention provides novel methods of preventing and treating, and for identifying novel compounds also useful as therapeutics for, such conditions. | 05-14-2009 |